IPT, Vitamin C and QOL
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Transcript of IPT, Vitamin C and QOL
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IPT, Vit C and QOL
2nd Annual RiordanIVC and Cancer Symposium
October 8 & 9, 2010
Bradford S. Weeks, M.D.
www.weeksmd.com [email protected]
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GOALS for this Presentation
1) understand the role of insulin inpotentiating chemotherapeutic benefits
2) understand the theoretical and practicalaspects of Corrective Cancer Care (including Insulin Potentiation Therapy)
3) begin to incorporate side -effect freechemotherapy in your clinical practice.
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Disclaimer:
no commercial interestor
conflict of interest declared
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A Common Understanding of a DOG
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RORY
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New Puppy Syndrome
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Rory really enjoying acar ride with Amelia
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Corrective Medicine and Psychiatry
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Thanks
and Congratulations!
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BSW (c) 2010 Tenzin Choedrak
Abram Hoffer Hugh Riordan David Horrobin
Otto Wolff Rudolf Steiner
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"A physician once told me that nothing arouses somuch bitter enmity and heated arguments among hiscolleagues, as the subject of cancer. This may be dueto the guilty recollections of cancer victims expiringwho might have been saved; or of the memories of patients pronounced hopelessly ill who recovered
under the treatment of a 'quack,' or whomiraculously lived without further treatment.
Possibly these guilt reactions and the remorse overexhausting the money of patients and their relatives
in futile cancer treatments, account for some of thesepsychological manifestations which are expressed inhostility and attack."
Nat Morris (written in 1958)
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Even Bill Gates took some risks in life
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Its not so important whether
you win or lose but rather,how you play the game.
My goal is to improvethe quality and quantity
of your life.
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The Role of Hope
There are no incurable illnesses,
only incurable people.
Paracelsus(1433-1541)
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Insulin Potentiation Therapy forthe Treatment of (people with)
Cancer
Part 1:The History and Rationale
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On July 27, 1921, Canadian scientists Frederick
Banting and Charles Best first isolated insulin andwithin a year, the first human sufferers of diabetes were receiving insulin treatments.
Lilly began manufacturing large doses of purifiedinsulin in November 1922.
In 1926, Donato Perez Garcia had 10 units of
insulin injected intravenously."
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The Development of the IPT Concept
Donato Perez Garcia, Sr., MD (1896 - 1971) first conceived of the therapy in Mexico City in 1926 and named it CellularTherapy to Change the Biophysical Biochemical Constantsof the Blood. Treated infectious illnesses: malaria, syphilisand poliomyelitis before focusing on cancer.
His son, Donato Perez Garcia y Bellon, MD (1930 - 2000) andand grandson - Donato Perez Garcia, Jr., MD (1957 - )followed in his footsteps.
Steven Ayre, MD learned about the therapy in 1975 andbecame the teacher of American doctors.
Bradford Weeks, M.D. learned IPT in 2001 from Dr. Ayreand is a certified clinical instructor in IPT for doctorswishing to learn this methodology.
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From the book, Terapia Celular or Cellular Cancer Therapy through Modification of Blood Physico-Chemical Constants or
Donatian Therapy - written by Donato I & II:
According to Terapia Celullar, an animalstudy with dogs was done in 1930 to testabsorption of anti-syphilis drugs, namely
mercury and NeosalvarsanPrior to this, the doctor had given himself
intramuscular injections.
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A human study with neurosyphillis patients wasconducted in Austin State Hospital in 1937, theresults of which are discussed in a letter by Dr.
Garcia dated September 1937.
On April 10, 1944, TIME magazine published anarticle on Dr. Garcia's "Insulin Shock Therapy,"in which a visit to the San Diego Naval Hospital isdiscussed, where Dr. Garcia treated malaria and
rheumatic fever patients.
Wed like him to come back and do it again.
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According to the timelinewritten by Dr. Donato,
"January 1946 - First breastcancer patient successfully
treated using IPT."
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Find a cure
before I grow
boobs!
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Conventional Chemotherapy
Pros:Powerful drugsEffective at killing cancer
Cons: Powerful drugsEffective at killing patients while killing cancer cellsCost (average oncologist mark up = 400%)Effectiveness rate = 2.1% (!!!)
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Problems with Conventional Chemotherapy1) Adequate intra-cellular concentrations requires
high dose, systemic administration of these drugs.
2) Lack of tissue specificity for drugs.
3) Consequence: Multiple tissue and organ toxicity(side-effects).
4) Note the tragic and little reported facts that 1)chemotherapy and radiation do NOT kill stemcells and 2) 99% of the cells in a cancerous tumorare NON-cancerous
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FACT: ~ 2% of all cancers respond to chemotherapy (!!!??)
FACT: Conventional Chemotherapy hurts more than it helps.
OPINION: The overall contribution of curative and adjuvant cyto - toxic chemotherapy to 5-year survival in adults was estimated to be 2.3% in Australia and 2.1% in the USA . . . chemotherapy only makes a minor contribution to cancer survival.To justify the continued funding and availability of drugs used in
cytotoxic chemotherapy, a rigorous evaluation of the cost-effectiveness and impact on quality of life is urgently required.
Morgan G, Ward R, Barton M. in his article:The contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies.See Clin Oncol (R Coll Radiol). 2004 Dec;16(8):549-60.)
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Why Do Cancer Cells Resist Chemotherapy?
1. resistant cells survive and reproduce survival of the fittest;2. cancer cells mutate and replicate3. gene amplification: hundreds of copies of genes which produce chemo-
inactivating proteins (inc. MDR gene expression).4. P-glycoprotein pump which pumps drug out of cells (inc. MDR expression).5. cancer cells inactivate the pump which brings the drugs into the cells (e.g.
decreased expression folate transporter with MTX).6. cancer cells learn to repair DNA damage caused by some chemo drugs
(inc. nucleoside excision repair with alkylating agents and platinum drugs;inc. O alkyl-guanine alkyl transferase with nitrosureas, procarbazine, andtemozolamide).
7. cancer cells learn to inactivate chemo drugs or decrease their activation(decreased folypolyglutamyl synthetase with MTX or decreaseddeoxycytidine kinase with cytosine arabinoside, fludarabine phosphate, andcladrabine).
8. increased detoxification (increased glutathione or GSH tranferase)
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What would be the Elements of an IdealSolution to this Chemotherapy Dilemma ?
1) To develop a method of differentiating the cancer cellpopulation from the normal cell population.
2) To deliver lowered doses of drug more specificallyinto this differentiated cancer cell population.
3) To maintain and /or enhance chemotherapys cell -killing effectiveness in cancer cells.
4) To reduce / avoid chemo side effects in normal cells.
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Which box are you thinking outside of?
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Insulin Potentiation Therapy
Utilizes Insulin to Modify EndogenousMechanisms of Malignancy
Selectively Targets Cancer CellsEnhances Anti-cancer Drug EffectsVery Low Doses of Chemotherapeutic Agents
Almost Completely Eliminates Dose RelatedSide Effects.
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Insulin Receptors (IRs) & Cancer Cells
# of IRs on cancer cells is much greater than nl cells
IR count correlates with tumor size and histological
grading.
The binding capacity and affinity for 125-I labeledinsulin was found to be 9 times as great in breastcancer cells than normal cells.
IRs do not down regulate as readily and can have1000 fold resistance to receptor down-regulation.
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Mammals have 100 to 100,000insulin receptors per cell.
Cancer cells have from 6 to 17
times more IRs per cell thannon-cancer cells .
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Insulin & Cancer Cells
1) Insulin stimulates cell replication.
2) Insulin is produced by cancer cells (i.e. biopsyspecimens produce insulin)
3) Cytoplasmic B-subunit of Insulin has tyrosine
kinase activity (oncogene product)
4) insulin resistance increases cancer risk.
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Elevated IGF levels
Hodgkins & Non -Hodgkins Lymphoma Renal AdenocarcinomaCervical & Uterine Carcinoma
Breast, Colon, and Lung CarcinomaLymphoblastic leukemiaAmount of IGFs correlates with stageCancer cells have up to 10 times more IGF receptors
on their surfaces.Treatment causes the IGF levels to decrease.
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Insulin and IGF-1 operate autonomouslyat the cellular level within tumors topromote tumor growth.
IGF-1 is the major anabolic hormonewhile insulin regulates and provides
the fuel for these processes.
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Rapidly growing tumors are more sensitive tochemotherapy than slow-growing tumors.
Studies at George Washington University,National Cancer Institute and
M.D. Anderson Hospital & Tumor Institutetested and proved that insulin doespotentiate the effects of chemotherapy.
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Hence, the results of our experimentsindicate that tumor-specific growthstimulatory hormones can be utilized toovercome the cyto-kinetic drug resistance.thereby render subpopulations of tumor
cells vulnerable to the lethal effects of cellcycle-active drugs that otherwise wouldhave remained inert to their effects and
might have constituted a potential source of late treatment failure.
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After IV Insulin:
Membrane EffectImproved drug penetration into cancer cellsUse lower doses to reduce side effectsShorten treatment cycle intervals
Metabolic EffectIncreased proportion in S phase.Increase rate of cell kill per cycle
Cellular Differentiation EffectExcess IR & IGF-R on cancer cellsSpecifically targets cancer smart bomb Relative sparing of normal tissue from toxicity
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In vitro, after adding insulinto an asynchronouspopulation of breast cancer
cells, the S phase fractionwas 66% compared to only
37% in the controls.
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From Treating Cancer with Insulin Potentiation Therapy p 84by Ross Hauser, M.D. 2002 Pub: Beulah Land Press
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Insulin and Appetite
IPT changes the pathophysiology of thefatigued, depressed and anorexic patient.
Insulin stimulates appetiteResults in weight gainProduces euphoria
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Human breast cancer cells have
six times more insulin receptors (1) and ten times more IGF-I receptors(2) than normal tissues in the body.
1) Holdaway IM, Freisen HG. Hormone binding by humanmammary carcinoma. Cancer Res 37:1946-1952, 1977
2) Cullen JK et al. IGF-I receptor expression and functionin HBCC. Cancer Res 50:48-53, 1990
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Insulin enhanced the cytotoxiceffect of methotrexate in MCF-7human breast cancer cells in vitro
by a factor of up to ten thousand.(that is 10,000 fold )
Alabaster O, Vonderhaar BK Shafie SM. Metabolic modification byinsulin enhances methotrexate cytotoxicity in MCF-7 human breastcancer cells. Eur J Cancer Clin Oncol 17:1097-1103, 1981
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Preincubation of MDA-MB-231human breast cancer cells in vitrowith insulin resulted in an increased
intracellular accumulation of ellipticine with a concomitantincrease in cytotoxicity.
Oster JB, Creasey WA. Enhancement of cellular uptake of ellipticine byinsulin preincubation. Eur J Cancer Clin Oncol 1981, 17:1097-1103
Pretreatment with insulin enhances anticancer
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Pretreatment with insulin enhances anticancerfunctions of 5-fluorouracil in humanesophageal and colonic cancer cells
Ke ZOU1,2, Ji-hang JU1,2, Hong XIE1
Conclusion: These data suggest that insulinenhances anticancer functions of 5-FU whenit is treated before 5-FU for the appropriatetime in human esophageal and coloniccancer cell lines.
PUB Acta Pharmacol Sin 2007 May; 28 (5): 721 730 2007
The effect of insulin on chemotherapeutic
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The effect of insulin on chemotherapeuticdrug sensitivity in human esophageal and
lung cancer cellsJIAO Shun-Chang, HUANG Jing,
Conclusion As a reversible metabolic promoter,insulin enhances the cytotoxity of the
chemotherapeutic agents . It is possible to increasethe growth and metabolism of cancer cells first, inorder to enhance the chemosensibility, and thenadminister chemotherapeutic agents, thus
improving their therapeutic effects.
PUB: Natl Med J China, February 10, 2003; Vol 83, No 3, Page 195-197.
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Insulin fuels Cancer
Cancer cells eat glucoseCancer cells have 6x > insulin receptorsInsulin allows greater membrane permeabilityfor glucoseCancer cells have 10x > IGF-1 receptorsIGF-1 increases S phase (growth phase)
Synergetic membrane & metabolic effectElegant medicine: think PO vs. IV ABX
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Summary: Biochemistry of Insulin and Cancer
Glucose is the ONLY fuel cancer cells can useCancer cells have 6 to 17x > IRs than regular cellsCancer cells have 10 x > IGF-1 Rs than regular cells
INS+IR increases delta-9-desaturase which makescancer cells become permeableIGF-1 doubles number of cancer cells in S-phase;
increasing vulnerability to chemotherapy drugs
Cancer cells are selectively targeted so lower doses of chemo drugs preserves immune function
Appetite improves, weight and euphoria increase
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IPT is a chemotherapy-based protocol usinginsulin as a biologic response modifier of theendogenous mechanisms of malignancy.
In IPT, insulin is used to selectively targetcancer cells with lowered doses of chemotherapydrugs, enhancing drug effects on these cells and,
at the same time, effectively reducing dose-related chemotherapy side effects on host normaltissues.
Insulin Potentiation Therapy
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The Nature of Cancer
1) Aggressive or not?2) Curable or not?
3) Infectious or not?4) What is the role of mind/body?
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The Mechanisms of Malignancy
The combination of insulin andIGF-I operates autonomously at thecellular level within tumors, and thisoperation is free from any higherlevel of integrated control
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The Mechanisms of Malignancy (cont.)
The two work together in an autocrine and/orparacrine manner and in a complementaryfashion, with IGF-I being the major anabolic
hormone responsible for mediating messagesabout growth in the tumor, while insulinregulates and provides the fuel for theseprocesses.
Zapf J., Froesch E.R. Insulin-like growth factors/somatomedins:structure, secretion, biological actions and physiological role. Hormone
Res 24:121-130, 1986.
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Nature abhors a vacuum.
Empty or unfilled spaces areunnatural as they go against the
laws of nature and physics.
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Cancer is not the problem.
Cancer is an adaptive responseto the problem.
Toxic blood and tissue is theProblem
Every town has a garbage dump.Solution: make less trash, recycle.
To avoid cancer: eat non-toxic foods and eat less!
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Removing the tumor is the leastimportant step in curing cancer.
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The Three Steps
1) Take down cancer welcome sign2) Enhance immune system3) Reduce or kill cancer cells
Metaphor:Bailing a sinking boat vs. plugging the hole
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The Four Bodies
TheViolin Concert
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Corrective Cancer Care
The Health PyramidThe NETNutritionExerciseThought
LIFESTYLE FACTORS (85%)
Repair the NET Nutrition (get it) Exercise (use it) Thoughts (manage it)
Supplementand / or
Detoxify
Drugs Surgery
Hospital
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Nutrition
What comes in all 7 sensesQuality organic freshAdequate proteinHaelan 951Supplements:
MVMMSoul food
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Supplements
Prevent cancer cells from repairing themselves (caffeine)Force apoptosis (curcumin, tumeric)Support immune system
1. Theanine (increases interferon gamma)
2. Arginine (increases NKC and T-cell function)3. American ginseng (increases T-cell function)4. Melatonin (increases IL-2, epidermal growth factor)5. Avemar (increases T-cell function)6. Vitamin C and others
Prevent Metastases - Modified Citrus Pectin, Heparin,Thalidomide.
All of the above and more: Haelan 951
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Haelan 951
a raw, fermented, organic, non-GMO, whole soyproduct
This product contains all 5 of the super foodsdiscovered in 1991 by the National Cancerinstitute after their $20 million study searchingfor anti-cancer properties in fruits and vegetables:1) Isoflavones 2) Protease Inhibitors 3) Saponins4) Phytosterols 5) Phytic Acid Compounds
(Journal of the National Cancer Institute April 17,1991)
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Haelan 915 Benefits
1) Apoptosis is stimulated:
Clinical Implication: Apoptosis is the healthy,
appropriate cells death which occurs at the righttimes after a cell has lived it full normal life. Incontrast, cancer cells resist apoptosis and liveeternally thereby killing the cancer patient.
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Haelan 915 Benefits (cont.)
2) DNA Repair is enhanced.Clinical Implication: DNA damage is the hallmarkof cancer. If DNA is repaired a cell can stop being
cancerous.
3) Reactivates P-53 Tumor Suppressor GeneClinical Implication: This raises levels of P-21 inbreast, ovarian and prostate cancer cell andthereby suppresses cancer and allows apoptosis.
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Haelan 915 Benefits (cont.)4)P21 gene activity is increased
Clinical Implication: This lifesaving gene isderived from the anti-cancer gene P53 and allowsto cancer call death
5) Anti-angiogenesisClinical Implication: Angiogenesis is the creationof a blood supply to tissues low in oxygen. Withoutthis new blood supply, cancer cells can not grow.Avastin stops angiogenesis by destroying VEGF(vascular endothelial growth factor) systemicallywhich is fatal. Haelan 951 stops angiogenesiswithout destroying VEGF.
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Haelan 915 Benefits (cont.)
6) Reduces exosomesClinical Implication: These are particles thatinhibit immune defense against cancer, they
inhibit both NK cell function and gammainterferon.7) Increases BAX 500% compared with the drug
Doxorubicin (in cases of breast cancer)
Clinical Implication: This is a gene which killscancer cells via allowing apoptosis.
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Haelan 915 Benefits (cont.)
8) Decreases BCL2 200% - in comparison toDoxorubicin (in cases of breast cancer)Clinical Implication: This is a gene which allows
cancer cells to thrive by evading apoptosis.
9) Improves Anti-apoptotic Ratio of BAX/BCL2Clinical Implication: This means that the genesare now fighting cancer by enhancing apoptosis.
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Haelan 915 Benefits (cont.)
10) Reduces Estrogen LevelsClinical Implication: This is an anti-cancer effect
since it also reduces ER-a.
11) Increases Estrogen receptor-beta receptorsClinical Implication: These kill cancers by
increasing the amount of natural chemotoxic
agents like 2-methoxyestradiol as well as theirdelivery to the cancer cell.
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Haelan 915 Benefits (cont.)
12) Decreases Estrogen receptor-alpha receptors ER-a
Clinical Implication: These receptors allow cancercells to thrive and metastasize so they must besuppressed for your health.
13) Improves Ratio- ER-a/ER-b
Clinical Implication: This allows for appropriateapoptosis and restoration of low cancer risk.
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Haelan 915 Benefits (cont.)
14) Decreases the matrix metalloproteinases enzymeClinical Implication: This enzyme erodes collagen
surrounding the tumor and frees cancer stem cellsto spread through out the body creating metastaticdisease.
15) Produces Anti-Cancer metabolites
Clinical Implication: Some of the most important of these are 3-Beta Adiol and 2-methoxyestradiolwhich hunt down and kill cancer stem cells.
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Haelan 915 Benefits (cont.)
16) Prevents Protein Calorie Malnutrition(cachexia or starvation)
Clinical Implication: This reversal of cachexiais life-saving since cachexia kills 80% of cancer patients. We must at all costs avoidthe situation where you starve (no appetite!)
while the cancer gorges itself.
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Haelan 915 Benefits (cont.)
17) Decreases Viral and Bacterial BurdensClinical Implication: Haelan 951 cleans house
and allows the immune system to work
without distraction.
18) Increases function of GADPH gene
expressionClinical Implication: This gene expression isone way to measure cancer die off.
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Haelan 915 Benefits (cont.)
19) Shuts Down NF-kB Mutation PathwayClinical Implication: Cancer cells are smart and
they try to mutate using the NF-kB pathway inorder to escape death when the immune system orthe chemotherapy is applied.
20) Enhances tumor necrosis factor (TNF)
Clinical Implication: TNF is a pillar of our immunesystem required to fight cancer.
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Haelan 915 Benefits (cont.)
21) Non-Specific Immune Stimulation Increased400%
Clinical Implication: the symbiosis of taking aproduct offering the 5 super foods (Haelan 951)and the myriad benefits described above amountto a huge immune boost. It increases macrophagephagocytosis by three-fold and double thenumber of active macrophages.
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Haelan 915 Benefits (cont.)
22) Gives clearer margins for surgical removal of tumors
Clinical Implication: If surgery is indicated, the goalis 1) to remove the cancerous cells and 2) to cut
away leaving a clean margin meaning leaving noresidual cells.
23) Overcomes depression and improves quality of
lifeClinical Implication: When the soul and spirit areless troubled, the immune system thrives.
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Curcumin, the yellow pigment found inthe spice turmeric and a key ingredientin yellow curry inhibits melanoma cellgrowth and stimulates tumor cell death
via apoptosis
potent antioxidant, anti -inflammatoryand cancer terminating effects
CANCER August 15, 2005
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Proteolytic Enzymes (away from food):
1) selectively attack and kill cancer cells2) clean up after themselves (debris)
3) unmask cancer cells ( membrane effect)4) prevent metastatic disease5) offer systemic immune enhancement
6) compelling scientific /clinical record7) excellent risk/benefit ratio
VITAMIN D3
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VITAMIN D3
A preponderance of evidence from the bestobservational studies... has led to the conclusion thatpublic health action is needed.
Primary prevention of these cancers has beenlargely neglected, but we now have proof that theincidence of colon, breast and ovarian cancer can bereduced dramatically by increasing the public's
intake of vitamin D."Professor Cedric Garland the University of San Diego, Californiaafter reviewing 63 recent studies on vitamin D and cancer.
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Vitamin C plus Vitamin K3
1. Vitamin K3 alone has demonstrated anti-tumoractivity against multiple rodent and humancancer cell lines.
2. Synergism noted with doxorubicin, 5 FU,vinblastine, vincristine, mitomycin, bleomycin,cisplatin, mitoxanthrone, MTX, and manyothers.
3. Phase I trials in humans 400-500 mg/day showedno toxicity in combination with mitomycin.Phase II trials of IV K3 (2.5 gms/m2) withmitomycin showed objective response but 30%showed hemolysis (Gold, Cancer Treat Rep, 1986)
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Vitamin C Plus Vitamin K3 contd
1) Vit C and K3 combination showed synergisticactivity in a 100/1 ratio in breast, endometrialand oral epidermoid carcinoma cell lines inconcentrations 10-50 times lower than for theindividual vitamins (Noto, et al, Cancer, 1989).
2) Co administration of C plus K3 with adriamycin,
bleomycin, mitomycin C, vincristine or cisplatinincreased growth inhibitory effect by 3-14 fold(Buc Calderone, et al., Curr. Med. Chem. 2002).
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Vit C and K3: The Mechanism of Action
High levels act via oxidative stress and arecytotoxic via necrosis or autoschizis.
Low levels kill by a non-oxidative mechanisminvolving transcription factors to produceautochizis and apoptosis.
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Vitamin C: Cancers silver bullet
1. Vitamin C alone has been found to have cytotoxic effectsagainst most cancer cell lines in vitro. These in vitroconcentrations are easily achievable in vivo with IV C.The mechanism appears to be intracellular accumulationof H2O2 with low catalase enzyme activity native to
cancer cells. (Dr. Mark Levine, NIH division of Diabetes andKidney diseases).
2. Vit C has also been found to potentiate the effects of chemotherapy drugs (Zaizen, et al., J cancer Res Lin Oncol,1986; Prasad, et al, Pol J Pharmacol and Pharm, 1992; Koch andBiaglow, J Cell Physiol, 1978) and radiation therapy (Hanck, ProgClin Biol Res, 1988).
Oxygen breathing may be a cheaper and safer alternative to
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exogenous erythropoietin (EPO)
Recently discovered normobaric oxygen paradox demonstratesthat renal tissue can be stimulated to increase EPO production via a
simple pattern of oxygen breathing at normal atmosphericpressures. This leads directly to the hypothesis that oxygen
breathing may provide chemotherapy patients with a convenient andinexpensive alternative to ESAs. Stimulating endogenous EPO
production eliminates the small risk of immune system reactionassociated with ESAs. Further, the endogenous physiological EPO
doses provided by this method may be safer, in terms of cancer
mortality, than the exogenous pharmacological doses inherent inESA administration.
Author: R. Burk Medical Hypothesis published on line 5/ 11/ 07
S ifi i i l l i IV
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Specific nutritional supplements given IVafter insulin but before therapeutic moment
Resveratrol Quercetin
Theanine Proline
Glutamine Arginine
Acetyl-L -carnitine Niacinamide
Artemisinin N- Acetyl Cysteine
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Exercise
ActivityDoing justice to what comes inProcessingDigestingExpression
Creativity (our birthright!)
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Thought
CorThotThoughts create feelingFeelings are transientThoughts are directableReason for living
Quality of life
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Case#1: Hodgkins Lymphoma stage IV
65 year old male, otherwise healthyLump on neck no other symptomsPET results February 2010: Multiple areas of
abnormal metabolic activity seen in head and neck.Abnormal metabolic activity seen along retroaorticthoracic lymph node. L3-L4 skeletal lesions.Impression: stage IV Hodgkins lymphoma withmultiple stations of adenopathy in head and neck,chest, abdomen and pelvis.
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Proposed Treatment
Meds: Bleomycin
Assurance: Dont worry. We have anexcellent success rate with HodgkinsLymphoma: 6 months of Hell and then 2 yearsof recovery, but after that, you will be cancer
free.
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Conventional Treatment Course
2 treatments of conventional chemotherapy:Vinblastine, Cytoxan, Adriamycin,Prednisone, Procarbazine, Omeprazole,
ProchlorperazineSide effects: nausea,Never again. Id rather die.
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CCC starting April 2010
1) IPT chemotherapy: Bleomycin 1 unit, Adriamycin 6mg,Dacarbazine 20mg, Vinblastine 1mg.2) HDVC: 50g /450cc sterile water w/ 2cc Magnesium SO43) Alpha Lipoic Acid 600mg in 50cc nl saline4) Homeopathics:
Au Stibium Hyoscyamus Hepar Stannum 6/10Lien Cichorium Lymphocytes 8Thrombocytes 6 Erythrocytes 6
Oral Supplements: Haelan 951, MVMM, Niacin, Selenium,CoQ 10, vitamin D3, LDN 4.5mg
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Clinical Progress
PET/CT 4-14- 10: IMPRESSION: remarkableimprovement since 2-2-10 with near completeresponse. Oncologist: My treatment has kicked in.
Patient goers off protocol: alcohol, sugarPET/CT 6-11- 10: enlarged nodes on both sidesof the neck, supraclavicular space and themediastinum, retrocrural lymph nodes, skeletallesions at L3 L4. Disease progression seencompared to 2-2-10 PET/CT. Patient leapt back on CCC protocol.
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PET: 8/6/10
Head and Neck no evidence of adenopathyno focal lesions to suggest recurrence in the headand neck. Chest no abnormal metabolic activity seen in
nodes no new lesions no suspiciouspulmonary nodes Abdomen: no organomegaly, no adenopathy Skeleton: No focal suspicious lytic or blasticskeletal lesions seen. Impression: No PET CT evidence for residualor recurrent lymphoma.
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Case #2: Leiomyosarcoma (uterine)
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Case #2: Leiomyosarcoma (uterine)stage IV with mets to Lung
51 yr old woman, onset age 47Failed surgery, chemotherapy, and radiation.Gemzar & Taxotere, Adriamycin & Cis Platin, Ifosfamide& Mesna & Adriamycin, Gemzar & Taxotere,Dacarbazine, Yondelis trialPET/ CAT Jan 2010 Innumerable metastatic pulmonarylesions aggressive disease.Tumor markers Jan 2010 CA 125=173, CA 19-9 =70I am shocked it came back so quickly. Put your affairs in orderSeattle oncologist refused more care
CCC i M h 2010
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CCC starting March 2010
1) IPT: Cytoxan 150mg, Gemzar 200mg, Methotrexate 12.5mg2) HDVC: 50g /450cc sterile water w/ magnesium SO43) Alpha Lipoic Acid 600mg in 50cc nl saline
4) Homeopathics:Au Stibium Hyoscyamus Hepar Stannum 6/10Lien Cichorium Lymphocytes 8Thrombocytes 6 Erythrocytes 6
Oral Supplements: Haelan 951, MVMM, Niacin,Selenium, CoQ 10, vitamin D3, LDN 4.5mg
R di hi P
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Radiographic Progress
PET/CAT April 2010: The innumerablebilateral pulmonary metastatic lesions have shownsubstantial decrease in size and number. None of these lesions shows a significant degree of
metabolic activity. Abdomen/pelvis: stable, noevidence of local recurrence of metastatic disease.
PET/CAT July 2010: Essentially all of thepreexisting metastases are smaller and/or lessdense of current exam. No new lung metastasis.
T M k
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Tumor Markers
DATE CA 125 CA 19-9
January 2010 138 41
March 2010 53 33
June 2010 18 49
September 2010 15 35
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Case #3 Fallopian tube cancer
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pwith mets to Lung
67 yr old woman s/p breast cancer 1994(mastectomy with adjuvant chemotherapy andTamoxifen) then fallopian tube cancer 2000 thenrecurrence with mets to lung 2008.Tumor Markers 6/10:
CA 125 = 8883 CA 19-9 = 98PET/CT 5-29- 10: Interval worseningpersistent abnormal uptake, persistenthypermetabolic adenopathy
CCC t ti J 2010
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CCC starting June 2010
1) IPT Chemotherapy drugs: Cisplatin 5-10mg vs.Carboplatin 25-50mg, with Gemzar 50-100-200mg,
2) HDVC: 50g /450cc sterile water w/ magnesium SO43) Alpha Lipoic Acid 600mg in 50cc nl saline
4) Homeopathics:Au Stibium Hyoscyamus Hepar Stannum 6/10Lien Cichorium Lymphocytes 8Thrombocytes 6 Erythrocytes 6
Oral Supplements: Haelan 951, MVMM, Niacin, Selenium,CoQ 10, vitamin D3, LDN 4.5mg
T M k
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Tumor Markers
DATE CA 125 CA 19-9
June 8883 98
July 3249 92
August 1314 60
September 873 40
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The original Come Hither look.
C #4 C l t l Ad i
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Case #4 Colorectal Adenocarcinoma
Nov 2006 A 65 yr old man noted a mass protrudingfrom anus and blood in stool. Thought it washemorrhoids so did nothing for 11 months!
October 2007 doctor does a DRE and notes large massDx from Bx: Stage IV Colorectal Adenocarcinoma
December 2007 CAT rectal mass and liver met 7mm
March 2008 Pt. refused chemo, took radiation (28rounds of external beam) and Arimidex. Doing lotsof nutritional supplements. Comes for IPT.
C 3 C l t l CA td
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Case 3 Colorectal CA contd
CEA 12.3 on 10-22-07He was started on alternating IPT regimen 2X/wk5-FU 250mg, Mitomycin 2mg, Leukovorin 10mg 50 c cnl saline SIVP before the 5-
FU in , IM Intron rectal ozone insuflationalternate with5-FU 250mg, Leukovorin 10mg in 50 cc nl saline with Irinotecan 20mg/cc
orOxaliplatin 10mg with Ribavarin 200mg rectal ozone insuflation
On 12-03-07 CEA 19.8 ng/ml (nl
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IPT: alternating IPT regimen 2X/wk:1) 5-FU 250mg, Mitomycin 2mg, Leukovorin 10mg 50
cc nl saline SIVP before the 5-FUalternate with
2) 5-FU 250mg, Leukovorin 10mg in 50 cc nl salinewith Irinotecan 20mg/cc
or
3) Oxaliplatin 10mg with Ribavarin 200mg
With Intron IM and rectal ozone insuflation
The rest is standard
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The rest is standard
2) HDVC: 50g /450cc sterile H2O w/ mag SO4 2 cc3) Alpha Lipoic Acid 600mg in 50cc nl saline4) Homeopathics:
Au Stibium Hyoscyamus Hepar Stannum 6/10Lien Cichorium Lymphocytes 8Thrombocytes 6 Erythrocytes 6
Oral Supplements: Haelan 951, MVMM, Niacin,Selenium, CoQ 10, vitamin D3, LDN 4.5mg
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CEA REPORTS
Date Results10/22/07 12.312/03/07 19.812/26/07 16.9
01/07/08 15.604/09/08 1.607/09/08 Less than 0.510/19/08 Less than 0.501/21/10, 4/21/10, 7/21/10 - all Less than 0.5The oral chemotherapy chlorine dioxide started 12/14/07.Radiation therapy February through March 2008.Surgery to remove the cancer May 9th of 2008.
November 3 2008
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November 3, 2008
Dear Dr. Weeks,
Attached is a record of my CEA results correlated withtreatment modalities. IPT was very effective with no side-effects and allowed my surgery to be minimal and now I feelfine.
I have been keeping track of the billings for conventionaltreatments. The total for surgery and radiation treatment is in
excess of $150,000 but I do not have an exact figure. If I hadaccepted the chemotherapy that was repeatedly thrust uponme the bill would have been considerably higher. I am gratefulto you and the pioneers who are practicing IPT.
2010 Follow up of Case 3
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2010 Follow-up of Case 3
Dear Brad, It is good to hear from you.My health continues to be good and,
considering all of the surgery, my energyand ability to function and work are good.My emotional health and sense of wellbeing
are also good. IPT was a life saver.
For health maintenance I take a daily dose of
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seawater mineral extract that I make, a tablespoonof wheat germ oil and 1,000 mg of vitamin C.
On every day that the sun does not shine I take10,000 IU of vitamin D-3. About once each week I
take an Iodoral tablet. Each night before bed I take
a 3 mg tablet of melatonin and 1.25 oz of rum.Once every 60 days I take San Pedro cactus extract.
At the first sign of any serious physical problem I
would not hesitate to began a course of MMStreatment. Have you noticed that MMS has nowbeen suppressed by the FDA?
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2) Antioxidants and immune enhancing protocols dot i t f ith IPT b t th h b fit
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not interfere with IPT but rather enhance benefitand are protective of healthy cells and vitality.
3) Patients find the experience not unpleasant (asidefrom the therapeutic moment of low blood sugar).
4) Side-effect free effective chemotherapy is here!
S
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Summaryand
Invitation
Corrective Cancer Care
with Insulin Potentiation Therapy
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The Standard of Care is sub-therapeutic.
Only 10% of conventional oncologists
say they would take the medication theyprescribe if they had cancer.
In contrast, 100% of IPT doctors wouldtake their own medicine!
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"I die by the help of too many physicians."
Alexander the Greaton his deathbed, 323 B.C.
Corrective Cancer Care with IPT
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SafeEffectiveCost-effective
and
The longest continuous cancerchemotherapeutic protocol in thewestern hemisphere (1926-present)
Corrective Cancer Care with IPT cont
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Corrective Cancer Care with IPT cont.
Smart Bomb effect: Excess of insulin-sensitive receptors on human cancercells causes predominance of insulin
effect in cancer cells, sparing normalhost tissues = INCREASED SAFETY
Synergy of insulins membrane and metaboliceffects enhances anticancer drug action incancer cells = INCREASED EFFICACY
Wh ff b d th t d d
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Why we offer beyond the standard
of care therapies?
1) more effective treatment2) more grateful patients3) more personal and professional
satisfaction
Quality of Life
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Quality of Life
1) Appreciate all things at all times2) Laugh and cry3) Be Curious and allow surprises4) Participate (walk the dog!)
and5) Appreciate all over again!
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Rory reminding us to take the time
to stop and smell the flowers!
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Dear Dr. Weeks,After my amazing treatments at
your wonderful clinic, I feel
so fantastic that I thinkI can walk on water.
But I know that you can!
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We all can walk on water.It is only a matter of motivation .
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WELCOME TO VISIT US IN SEATTLE !
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Walking on Ebbys Landing Whidbey Island, with Rory.
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