Introduction to MBI and euSysbio programmes MBI/euSysbio Orientation Event for Aalto students...
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Transcript of Introduction to MBI and euSysbio programmes MBI/euSysbio Orientation Event for Aalto students...
Introduction to MBI and euSysbio programmes
MBI/euSysbio Orientation Event for Aalto studentsSeptember 7nd, 2012Juho Rousu
Two MSc Programmes
• euSysbio – Computational and Systems Biology– Erasmus Mundus programme jointly offered by KTH, Sweden
and IST, Portugal– Double degree programme, studies in two universities (e.g. 1st
year Aalto – 2nd year KTH or IST, and vice versa)
• MBI – Bioinformatics– In collaboration with University of Helsinki– Degree granted by Aalto
• Common coursebase, different degree structure• Biological studies offered by University of Helsinki for
both programmes• Internships & MSc thesis topics in research groups
euSysbio MBI
Academic staff – MBI/euSysbio at Aalto
Department of Information and Computer Science (ICS)• Merger of
• The Laboratory of Computer and Information Science
• The Laboratory for Theoretical Computer Science
• General research theme:• Advanced computational methods for modelling, analysing, and solving complex tasks in technology and in science
• Three centres of Excellence in Research• CoE in Computational Inference Research (Prof. Samuel Kaski, Prof. Erik Aurell)
• Algorithmic Data Analysis CoE (Prof. Juho Rousu, Jaakko Hollmen)
• CoE in Molecular Systems Immunology and Physiology Research (Prof. Harri Lähdesmäki)
Where everything happens
euSysbio: additional locations
Building blocks of bioinformatics and computational systems biology
Data analysisData mining
Statistical modeling
Signal processing Machine learning Computational sciences
Computer science& Algorithms
Software & databases Biology & medicineBiotechnology
Computational systems biology & Bioinformatics
Related research groups
• Internship positions and thesis topics come from research groups
• ICS department• Computational systems biology (Lähdesmäki)• Kernel Machines, Pattern Analysis, and Computational Biology
(Rousu)• Statistical machine learning and bioinformatics (Kaski)• Parsimonious modelling (Hollmen)
• Other institutes• University of Helsinki (Dozens of biological/biomedical research
groups)• VTT Technical Research Center of Finland (across the road)• Companies (Orion, Valio, …)
Example Thesis topics
• “Computational Comparative Study of blood TCR repertoire: Celiac Disease patients versus Controls”
• “Bayesian Integrative Modelling of Metabolic and Transcriptional Data Using Pathway Information”
• “Modeling the dynamics of human neuromagnetic brain rhythms”
•“Type 1 diabetes biomarkers in human whole blood transcriptome”
•“Effects of computational methods to detect copy number variation in autism research”
• “Computational analysis to reveal combinatorial histone modifications”
• ”Comparison of Metagenomic Data by identifying enriched Pathways in Metabolic Networks”
• ”Performance analysis of inverse covariance estimation methods for inferring biological networks from genomic data”
Closing Words
• MBI&euSysbio programmes are challenging, be prepared to work hard– If your mathematics and statistics skills are dusty, time to brush up
• Obtaining 60 credits per year is not a trivial task– If you feel you are not keeping up with the courses, please be in
contact with us (tutors, Kirsti, Juho) early rather than late • Good grades are important
– to get good internship/MSc thesis opportunities/Phd studies/employment
• Be punctual with deadlines of coursework– late submissions may result to lower grades for courses and thesis– euSysbio: failing to complete enough credits may cause problems
with your scholarship payments• Finally: enjoy Aalto and Finland!