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RADIO PHARMACYAN INTRODUCTION TO ITS

CLINICAL APPLICATIONS

By Rini Agustin

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Do you know radioactive?

SRA plus syndroma kutanius

Chernobyl

An accident in Radiography industry, in

Yanango, Lima PERU

Ir-192 (37 Ci / 1,37 TBq), 20 Feb. 1999

What is your mind if you hear

radioctive ?

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Radioactive is not always something that we

affraid of it, but it is also helpfull to human life

Clinical application of Radioactive

In Nuclear Medicine

- in the form of diagnostics, treatment, reasearch and clinical trials.

Radiopharmacy = Nuclear Pharmacymedicinal products for use in diagnosis and therapy =

radiopharmaceuticals

http://en.wikipedia.org/wiki/File:New_radiation_symbol_ISO_21482.svghttp://en.wikipedia.org/wiki/File:New_radiation_symbol_ISO_21482.svghttp://en.wikipedia.org/wiki/File:New_radiation_symbol_ISO_21482.svghttp://images.google.com.sa/imgres?imgurl=http://www.ehs.psu.edu/images/rad_sign02.gif&imgrefurl=http://doctorpistachio.blogspot.com/2006/12/j-funk-does-radioactivity.html&usg=__NKa3JmmLSqcKBZG631Ea93zw-Vw=&h=812&w=734&sz=68&hl=ar&start=49&itbs=1&tbnid=k6ZCPxvQkXxaNM:&tbnh=144&tbnw=130&prev=/images?q=radioactivity&gbv=2&ndsp=18&hl=ar&safe=active&sa=N&start=36

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Radioactive in the diagnosis of disease

(diagnostic radiopharmaceuticals)

to image the organs which have a problem correctly and clearly

Barium swallowexamination of upper GI tract

Non-imaging diagnostics

Radioactive Isotope labelling for tracing

i.e. More specific tests for thyroid function, renal function and

vitamin adsorption.

used in tracer techniques for measuring physiological parameters

(e.g. 51Cr-EDTAfor measuring glomerular filtration rate).

Radiopharmaceuticals for diagnostic imaging

(e.g.99mTC-methylene diphosphonate (MDP) used in bone scanning,

Non-osseus

uptake Tc-99m MDP : Pulmonary Carcinoma).

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Radioactive for therapyTreatment of disease:

(therapeutic radiopharmaceuticals)

Chromic phosphate P32 for lung, ovarian, uterine, andprostate cancers

Sodium iodideI 131for thyroid cancer

Samarium Sm 153for cancerous bone tissue

Sodium phosphate P 32for cancerous bone tissue and other types of cancers

Strontium chloride Sr 89for cancerous bone tissue

Palliative treatment - refers to the management of symptoms when the

underlying disease is untreatable or terminal. Radiotherapy may aid in

prolonging the life of dying patients.

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Conclusion

The use of Radioactive in clinical application : in

nuclear medicine and radiopharmacy, medicinal

products used for diagnostic and therapy

It require very specialist radioactive substances, A

specialist discipline, Specialslicensure, specialist

knowledge and skill