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4HospiMedica InternationalJune-July/2020

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although all material in this directory is compiled from sources believed reliable, Publisher cannot be held liablefor any errors, omissions or inaccuracies. Inclusion, or lack of it, in this directory, does not constitute any endorse-ment or expression of other opinion by Publisher with regard to companies, their products or services.

HospiMedica 500Companies in alphabetical order . . 19 Companies by Country . . . . . . . . . . 44

Annual Review 2019Medical Imaging . . . . . . . . . . . . . . . . 5Critical Care . . . . . . . . . . . . . . . . . . . 9surgical Techniques . . . . . . . . . . . . 13Health IT . . . . . . . . . . . . . . . . . . . . 18

BUYER’S GUIDE 2020Medical Imaging . . . . . . . . . . . . . . . 20Critical Care . . . . . . . . . . . . . . . . . . 26surgical Techniques . . . . . . . . . . . . 36Patient Care . . . . . . . . . . . . . . . . . . 42

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5 HospiMedica InternationalJune-July/2020

crystalline Testing Rapidly evaluates Radiation exposure

t esting crystalline insulators found in most modern electronics could fa-cilitate emergency response dosimetry or nuclear forensics, claims a

new study. Developed by researchers at North Carolina State University(NC State; Raleigh, USA; www.ncsu.edu), the new approach relies on test-ing surface mount resistors, found in everything from thumb drives to smart-phones, in order to measure background radiation level. The resistor is firstremoved from the electronic device and placed in a thermally stimulated lu-minescence reader. Spectra reading related to the number of electrons foundin flaws inherent to the sample's crystalline structure are then measured andfed into a custom single aliquot regenerative (SAR) protocol to calculate ra-diation exposure.

world’s First AI-based Algorithms for eD Receive ce certification

Z ebra Medical Vision (Kibbutz Shefa-yim, Israel; www.zebra-med.com)

has received two new CE marked registra-tions for its deep learning algorithms thathelp radiologists and Emergency Room(ER) staff to prioritize acute conditions forthe first time in both CT scans and X-raysand reduce reports turnaround time(RTAT). The artificial intelligence (AI)technology can flag time-critical casessuch as pneumothorax in chest X-rays andbrain bleeds in CT scans. The technologyreduces the time it takes radiologists andER staff to spot acute conditions by 80%,which in turn, improves the quality andtimeliness of treatment.

new Dosimeter MeasuresPhoton and beta Radiation

a Bluetooth-enabled dosimeter withdual detectors addresses internation-

al requirements for independent deep andshallow measurements of both photonand beta radiation. The Mirion Technologies(San Ramon, CA, USA; www.mirion.com)Instadose2 dosimeter provides the abilityto wirelessly capture, transmit, measure,analyze, and report radiation dose expo-sure any time, and is ideally suited forhigh-energy, beta-sensitive environments,including nuclear medicine and radiother-apy settings, for interventional radiology,in nuclear power plants, and in researchfacilities that utilize beta emitting energysources. Instadose2 utilizes BluetoothLow Energy (BLE) to transmit dose data toa variety of devices, eliminating the time-consuming process of badge collection,processing, and redistribution.

Deep Learning Model classifies chest X-Rays

c ombining deep learning (DL) modelswith adjudicated image labels can

help classify clinically important findingson chest X-rays, claims a new study. Re-searchers at Google Health (MountainView, CA; https://health.google), ApolloRadiology International (Hyderabad, In-dia; https://apolloradiologyintl.com), Cal-ifornia Advanced Imaging (Novato, USA;www.cairad.com), and other institutionshave developed DL models that can accu-rately classify four clinically important

chest X-ray findings - pneumothorax, nodules and masses, fractures, and air-space opacities. The target findings were selected in consultation with radi-ologists and clinical colleagues, so as to focus on conditions that are bothcritical for patient care, and for which chest X-ray images alone are an im-portant and accessible first-line imaging study.

new MRI Technique Improves breast cancer Screening

a new magnetic resonance imaging (MRI) waistcoat packed with flexibleradio frequency (RF) coils could screen women for breast cancer faster

and with less disadvantages, claims a new study. Under development at theMedical University of Vienna (MedUni; Austria; www.meduniwien.ac.at),Université de Lorraine (Nancy, France; www.univ-lorraine.fr), and other in-stitutions, the prototype waistcoat device is a mechanically flexible, receive-only array that contains 32 RF coils sewn into the fabric, each consisting ofan 18 centimeter long coaxial cable formed into an eight centimeter wideloop. A receiver unit at the end of the cable feeds the signal into the com-puter. Motion sensors built into the vest monitor the patient so that it cancancel out breathing movements that distort the image.

For more information on news developments listed below, log-on to www.hospimedica.com and type appropriate keyword(s)into search engine to access full story from news archive

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t o p N e W S d e v e l o p M e N t S o F 2 0 1 9



novel Algorithm Shortens MRI Scans to nearly a Minute

a new multicontrast magnetic resonance imaging (MRI) technique cancut down the time needed to complete a scan to about 70 seconds,

claims a new study. Developed by researchers at Karolinska Institutet (KI;Solna, Sweden; www.ki.se), Karolinska University Hospital (Stockholm,Sweden; www.karolinska.se), GE Healthcare (GE, Little Chalfont, UK), andother institutions, the echo planar image mix (EPIMix) MRI technique com-bines contrast T1 -FLAIR, T2 -weighted, diffusion-weighted images (DWI),apparent diffusion coefficient (ADC), T2*-weighted, and T2 -FLAIR imagesinto one multicontrast MRI technique. EPI is capable of acquiring an entireMRI in only a fraction of a second; in single-shot EPI, all the spatial-encodingdata of an image can be obtained after a single radio-frequency excitation,resulting in high-quality images comparable to conventional MRI, but withmajor advantages over conventional MRI that include reduced imagingtime, decreased motion artifact, and the ability to image rapid physiologicprocesses of the human body.

Proton Therapy Lowers Risk of Radiation Therapy Side effects

a new study suggests that cancer patients undergoing proton radiationtherapy (RT), instead of conventional photon treatment, are at a signif-

icantly lower risk of experiencing side effects. Researchers at the Universityof Pennsylvania (Penn; Philadelphia, USA; www.upenn.edu), WashingtonUniversity School of Medicine (WUSTL; St. Louis, MO, USA; https://med-icine.wustl.edu), and other institutions conducted a study involving 1,483cancer patients, 391 of whom received proton therapy and 1,092 who un-derwent photon treatment. The patients suffered from non-metastatic braincancer, head and neck cancer, lung cancer, gastrointestinal cancer, and gy-necologic cancer, and were treated with concurrent chemotherapy and ra-diation. According to lead author Brian Baumann, MD, of Penn andWUSTL, “our clinical experience is that concurrent chemoradiation therapypatients treated with protons, rather than photons, tend to have fewer sideeffects."

novel Magnetic Metamaterial boosts MRI Performance

a new magnetic metamaterial enables a marked boost in radio frequency(RF) field strength, producing clearer MRI images at double the speed.

Developed at Boston University (BU; MA, USA; www.bu.edu), the magnet-ic metamaterial is composed of an array of unit cells featuring metallic he-lices known as helical resonators. The three-centimeter-tall structures, cre-ated from three-dimensional (3D) printed plastic and coils of thin copperwire, can be grouped into a flexible array that is pliable enough to cover aperson’s kneecap, abdomen, head, or any part of the body in need of imag-ing. When the helices array is in position, the resonators interact with themagnetic field of the MRI scanner, boosting the signal-to-noise ratio (SNR).

Ultrasound Monitor Delivers blood Flow Data on Demand

a novel system combines 3D ultrasound imaging with advanced algo-rithms to automate visual and quantitative blood flow monitoring after

surgery. The Sonavex (Baltimore, MD, USA; www.sonavex.com) EchoSuredevice is a portable ultrasound system designed for non-expert users to rap-idly detect postoperative clot formation by automatically identifying loss offlow through blood vessels. Echosure is designed to work with theEchoMark implant, which serves as a marker for soft tissue sites during sur-gery. As a result of its ultrasonic reflective properties, doctors can preciselyvisualize the area during follow-up evaluations. EchoSure uses deep learningalgorithms to derive where the ultrasound beam is coming from, and canthen compute the volumetric flow rate through the vessels of interest so itcan quantify the blood flow rate over time.

Ultrasound-on-chip Transforms Field Diagnostics

a handheld, single-probe whole body system is making ultrasoundtechnology universally accessible and affordable. The Butterfly Net-

work (New York, NY, USA; www.butterflynetwork.com) Butterfly iQ is amulti-mode (M-mode, B-mode, and Color Doppler) ultrasound device lessthan 15 centimeters long and weighing just 313 grams, allowing it to eas-ily fit into a pocket. Butterfly IQ is programmed with 18 preset scanningprograms, which enable diagnostic ultrasound imaging of peripheral ves-sels, including for carotid and arterial studies and procedural guidance;and cardiac, abdominal, urology, gynecological; fetal/obstetric, and mus-culoskeletal use. Jonathan Rothberg, founder and chairman of ButterflyNetwork, said, “Two thirds of the world's population has no access tomedical imaging. Butterfly's Ultrasound-on-a-Chip technology enables alow-cost window into the human body, making high-quality diagnostic im-aging accessible to anyone.”

Pocket Ultrasound Scanners Revolutionize Patient care

a second-generation series of wireless ultrasound scanners put the powerand image quality of larger, more expensive systems in an affordable

device that fits in a pocket. The new Clarius Mobile Health (Clarius; Burn-aby, BC, Canada; https://clarius.com) line-up includes two multipurposescanners for whole body imaging, the convex C3 HD, which operates at afrequency of 2-6 MHz, and the phased array PA HD - Cardiac/EMED,which operates at a frequency of 1-4 MHz. Both systems scan a maximaldepth of 40 cm and are designed for use in abdominal, lung, cardiac,ob/gyn, superficial, and vascular access applications. The second generationdevices are almost half the size of the original devices, but have eight timesthe processing power of most handheld scanners. In addition, four scannersdedicated to specialties such as sports medicine and anesthesia are nowavailable.

Ghost Tomography May Lead to Safer 3D Imaging

a n unconventional approach known as ghost imaging could revolution-ize three-dimensional (3D) tomography screening for early warning

signs of disease. Developed at Australian National University (ANU; Canber-ra; www.anu.edu.au), Monash University (Melbourne, Australia; www.monash.edu), and The European Synchrotron (Grenoble, France; www.esrf.eu), ghost tomography (GT) uses random x-ray intensity patterns to il-luminate an object from various angles, with each beam split in two. Thepattern is recorded in the primary beam, which acts as a reference since itdoes not penetrate the object; the secondary beam passes through the ob-ject, with X-ray transmission recorded by a single-pixel detector. “3D X-rayghost imaging, or ghost tomography, is a completely new field, so there's anopportunity for the scientific community and industry to work together toexplore and develop this exciting innovation,” concluded Dr. Kingston. “Avariation of our approach doesn't require an X-ray camera at all, just a sensor- this would make a 3D medical imaging setup much cheaper.”

AI Accelerates chest X-Ray Analysis

a novel artificial Intelligence (AI) system can dramatically reduce thetime needed to receive an expert radiologist opinion on abnormal

chest X-rays with critical findings, claims a new study. Developed by re-searchers at King’s College London (KCL; UK; www.kcl.ac.uk), the Uni-versity of Warwick (Coventry, UK; https://warwick.ac.uk), and other in-stitutions, the AI system was developed using 470,388 fully anonymizedinstitutional adult chest radiographs acquired from 2007 to 2017. The re-sults revealed that normal chest radiographs (used to diagnose and moni-tor a wide range of conditions affecting the lungs, heart, bones, and softtissues) were detected by the AI system with a sensitivity of 71%, speci-ficity of 95%, PPV of 73%, and NPV of 94%. The average reporting delayusing the algorithms was reduced from 11.2 to just 2.7 days for critical

MEDICAL IMAGINGMEDICAL IMAGING Annual Review 2019Annual Review 2019


imaging findings, and from 7.6 to 4.1 days for urgent imaging findings,when compared with historical data. The study was published on Janu-ary 19, 2019, in Radiology.

Space exploration Technology Provides bedside Imaging capabilities

a new flat-panel source (FPS) makes portable, low-dose, and low-costthree-dimensional (3D) digital tomosynthesis (DT) more accessible.

The Adaptix (Begbroke, UK; www.adaptiximaging.com) FPS is composedof an array of cold cathode field emitters fitted into a sealed unit; eachfield emitter generates a conelet of X-rays, while a proprietary system, de-signed to avoid the common problem of high-voltage switching, allowsfor each X-ray emission to be addressed and individually controlled, thuseliminating large numbers of overlapping X-rays. An additional benefit ofthe flat panel design is that it can cover many different angles, allowingdepth information to be derived through DT.

Surgical Tractography Tool Automates white Matter Segmentation

a n automated segmentation feature visualizes and highlights brainwhite matter bundles of interest instantly, allowing brain surgeons

to identify safer approaches. Part of the Synaptive Medical (Toronto;Canada; www.synaptivemedical.com) Modus Plan surgical planningsoftware tool, The segmentation feature uses 3D visualization overlaidon an anatomical scan derived from preoperative imaging and volumet-ric anatomical and diffusion tensor imaging (DTI) renderings. The auto-mated tract segmentation feature provides surgeons with the ability tominimize disruption of white matter, which is or-ganized into bundles that may correspond to dif-ferent brain functions, and whose particular lo-cation differs on a per-patient basis.

Scanner Produces whole-body PeT Images in Seconds

a modified positron emission tomography(PET) scanner can create three dimensional

(3D) renderings of the entire human body in aslittle as 20 seconds, and with less radioactive ex-posure. Developed by researchers at the Uni-versity of California Davis (UCD; USA; www.ucdavis.edu), the University of Pennsylvania(Philadelphia, PA, USA; www.upenn.edu), Unit-ed Imaging Healthcare (UIH; Shanghai, China;www.united-imaging.com), and other institu-tions, the two-meter long device is made of eightPET scanner rings, each 25 centimeters thick,that can image the entire body at once. By com-bining eight scans into one, total body renderingcan be accomplished in 1/40 of the time of a con-ventional PET scanner, as well as using 1/40 ofthe radiation dose. The modified PET scanner,which is called Explorer, could be especially help-ful for imaging children, who tend to movearound inside a scanner and ruin the measure-ments,

web-based Radiology App enables DIcOM Image Sharing

a new, web-based radiology application en-ables doctors to view, edit, and share images

through any platform (Windows, Android, Linux,iOS) without the need to install any software. TheHNC Virtual Solutions (Wixom, MI, USA; https://hncvirtualsolutions.com) imaging platform al-lows doctors to load a digital imaging and com-munications in medicine (DICOM) image directlyfrom any cloud-based or local source, such as afile folder, CD, laptop, USB flash drive or any oth-er external device, providing access to real-timecommunication and collaboration, as well as of-fering numerous functionalities, such as screensharing, screen recording, messaging, and au-thentication. Once loaded, the image can beshared to anyone in the world without the needto first upload it to a server or cloud.

Mathematical Model Improves Radiation Therapy

a new mathematical model spatially optimizes external beam radiationtherapy (XRT) in order to significantly increase the number of brain tu-

mor cells killed during treatment. Developed at the University of Waterloo(UW; Canada; https://uwaterloo.ca) and the Massachusetts Institute ofTechnology (MIT, Cambridge, MA, USA; www.mit.edu), the new model op-timizes one-step and two-step radiation profiles during the first and secondXRT fractions, while setting a cap on the total dose a patient could receivethroughout treatment. Tumor anatomy was then sectioned into multipleportions, with the area most densely populated with cells being one portionand the remainder of cells the other.

bimodal contrast Agent Advances Medical Imaging

a new study details a two-in-one probe made of a contrast agent for mag-netic resonance imaging (MRI) and a dye for photoacoustic imaging (PI).

Developed at the University of Mons (Belgium; https://web.umons.ac.be) and the Center of Microscopy and Molecular Imaging (CMMI;Charleroi, Belgium; www.cmmi.be), the bimodal agent combines the MRIgadolinium agent Gd-PCTA, and an organic fluorophore dye called ZW800-1.The bimodal probe enhances MRI contrast as strongly as a commercial MRIagent, while at the same time providing a photoacoustic signal similar to theoriginal PAI probe. The probe can thus provide hybrid images with a highanatomical resolution provided by MRI, and precise localization of the contrastagent thanks to PAI. Preliminary relaxometric and photoacoustic characteriza-tions indicate that the bimodal agent fulfills its function. The study was pub-lished on June 26, 2019, in the European Journal of Inorganic Chemistry.


MEDICAL IMAGINGMEDICAL IMAGINGAnnual Review 2019Annual Review 2019

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MR elastography Visualizes Tumor Stiffness and Density

a new study suggests that magnetic resonance (MR) elastography cannoninvasively and quantitatively map the viscoelastic properties of tu-

mors in vivo. Researchers at University College London (UCL, UK;www.ucl.ac.uk), The Royal Marsden NHS Foundation Trust (London, UK;www.royalmarsden.nhs.uk), and the Institute of Cancer Research (ICR;London, UK; www.icr.ac.uk) conducted a study in mice that coupled MRelastography and computational histopathology to interrogate the contribu-tion of collagen to tumor biomechanical phenotype in several different tu-mor types, including breast cancer, pancreatic cancer, medulloblastoma,glioblastoma, and neuroblastoma xenograft.

novel Imaging Technique could Help characterize Thyroid Disorders

a combination of multispectral optoacoustic tomography (MSOT) and ul-trasound can be used for initial evaluation and differential diagnosis of

thyroid disorders, according to a new study. Researchers at University Hos-pital Münster (UKM; Germany; www.ukm.de), Munich Technical Universi-ty (TUM; Germany; www.tum.de), and other institutions conducted a studyto evaluate the viability of using hybrid MSOT/ultrasound to image thyroiddisorders, such as Graves’ disease and thyroid nodules. The results revealedthat hybrid MSOT/ultrasound imaging found significantly higher deoxy-genated hemoglobin and total hemoglobin, as well as significantly lower fatcontent, in Graves' diseases lobes, as compared with healthy controls.When comparing the thyroid nodules imaged with MSOT/ultrasound, ma-lignant thyroid nodules showed significantly lower saturation of hemoglobinand lower fat content than benign nodules. The study was published in theOctober 2019 issue of The Journal of Nuclear Medicine.

AI-based Diagnosis System Detects Over 30 Medical conditions

a new cutting-edge all-in-one medical image diagnosis system named AI-HuB can detect and monitor more than 30 medical conditions from 14

regions of the body. Developed by JLK Inspection (Seoul, South Korea;http://jlkgroup.com), AIHuB conducts analysis from MRI, CT, X-ray andmammography imagery using AI-enabled technology that encompasses awide variety of diagnostic techniques to pinpoint illnesses such as stroke,Alzheimer's and cancer. The ability to provide optimal diagnosis supportbased on deep learning technologies, unique algorithms and imaging proces-sion techniques will be a great benefit to all patients, whether suffering fromminor or major ailments.

AI Algorithm Outperforms Human experts In Identifying cervical Precancer

r esearchers from the National Institutes of Health (Bethesda, MA,USA; www.nih.gov) have developed a computer algorithm that can

analyze digital images of a woman’s cervix and accurately identify precan-cerous changes that require medical attention. The artificial intelligence(AI) approach, called automated visual evaluation, could potentially revo-lutionize cervical cancer screening, especially in low-resource settings.Health workers can easily perform automated visual evaluation by using acell phone or similar camera device for cervical screening and treatmentduring a single visit. Additionally, the approach can be performed withminimal training, making it ideal for countries with limited health care re-sources, where cervical cancer is a leading cause of illness and deathamong women.

new Roadmap Outlines AI Research Priorities for Medical Imaging

a report establishing a research roadmap outlining priorities in founda-tional and translational research in artificial intelligence (AI) for med-

ical imaging has been published in the journal Radiology. A second report ontranslational research in AI focusing on real-world AI problems will be pub-lished in the Journal of the American College of Radiology (JACR;www.acr.org) in early summer of 2019. Both reports are the outcome of aworkshop convened last August by the National Institute of Biomedical Im-aging and Bioengineering at the NIH to explore the future of AI in medicalimaging. The workshop brought together government, industry, academiaand radiology specialty societies to create a roadmap that sets a path forwardfor both foundational research in AI and the translational research necessaryto deliver AI to clinical practice.

new VR Technology Puts Interventional Radiologists Inside 3D blood Vessels

a team of researchers from the University of Washington (Seattle, WA,USA; www.washington.edu) has pioneered virtual reality (VR) technol-

ogy that puts the operator inside 3D blood vessels. By following an anatom-ically correct, dynamic, 3D map of a phantom patient's vessels, intervention-al radiologists can navigate a catheter, a thin flexible tube inserted into ar-teries and veins and steered to any organ in the body, through junctions andangles. The catheter's tip is equipped with sensors that visually represent itsexact location to the VR headset.

Imaging Societies Publish Statement On Use of AI in Radiology

e xperts in the use of artificial intelligence (AI) in radiology from many ofthe world’s leading radiology, medical physics and imaging informatics

groups have published an aspirational statement to guide the developmentof AI in radiology. The multi-society statement focuses on three major areas:data, algorithms and practice. The authoring societies include the AmericanCollege of Radiology (ACR; www.acr.org), European Society of Radiology(ESR; www.myesr.org), Radiological Society of North America (RSNA;www.rsna.org), Society for Imaging Informatics in Medicine (SIIM;https://siim.org), European Society of Medical Imaging Informatics (Eu-SoMII; http://www.eusomii.org), Canadian Association of Radiologists(CAR; https://car.ca) and American Association of Physicists in Medicine(AAPM; www.aapm.org).

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Supraglottic Airway Aids Pre-Hospital Resuscitation

a novelsupraglottic airway device (SAD) creates a non-inflatableanatomical seal of the pharyngeal, laryngeal, and peri-laryngeal

structures. The Intersurgical (Wokingham, UK; www.intersurgical.com)i-gel second-generation SAD is based on a cuff that creates an anatomicalseal during routine or emergency anesthesia, intubation with fiberopticguidance, and for resuscitation. Supraglottic airway devices are used tokeep the upper airway open for unobstructed ventilation. The new de-vices have further improved efficacy and utility by incorporating designchanges that provide more dependable positive-pressure ventilation, arebetter able to act as conduits for tracheal tube placement, and have a re-duced risk of pulmonary aspiration of gastric contents.

Active Irrigation Device Manages Intracranial bleeding

a novel controlled fluid exchange system allows neurosurgeons to ac-tively manage intracranial pressure (ICP) and cerebrospinal fluid

(CSF) drainage. The IRRAS (Stockholm, Sweden; https://irras.com) IR-RAflow device is an ICP monitoring and drainage system designed todrain intracranial fluid in order to reduce ICP in patients when an exter-nal drainage and monitoring system is needed for less than 24 hours. “IR-RAS is focused on the treatment of hemorrhagic strokes that constituteabout fifteen percent of all strokes, but account for over forty percent ofstroke associated deaths,” said Kleanthis Xanthopoulos, PhD, executivechairman of IRRAS. Former systems that relied solely on gravity alone,and as a result, they have been plagued by blockages that can lead to in-efficient drainage and other complications.

Ultrathin Stent Helps Treat coronary Artery Disease

a n ultrathin drug-eluting stent (DES) offers a new hybrid strategy inthe treatment of coronary artery disease (CAD) by offering both ac-

tive and passive components. The Biotronik (Berlin, Germany;www.biotronik.com) Orsiro DES is based on a high performance PRO-Ki-netic Energy double-helix stent platform, which makes use of a uniquecobalt-chromium alloy that allows for thinner (60 µm diameter) stentstruts, while still maintaining optimal radial strength and radiopacity.Ryan Walters, President of Biotronik, said, “Interventionalists can rely onOrsiro's deliverability to treat complex lesions and challenging subgroupsto achieve unprecedented patient outcomes. Patients, physicians andhealth systems deserve the best.”

Automated Health Data Tools Detect Sepsis in newborns

M achine-learning models can identify neonatal intensive care unit(NICU) infants at risk of sepsis hours before clinicians recognize the

life-threatening condition. Researchers at the Children's Hospital ofPhiladelphia (CHOP; PA, USA; www.chop.edu) conducted a retrospec-tive case control study of infants hospitalized in the CHOP NICU be-tween September 2014 and November 2017 who received at least onesepsis evaluation before 12 months of age. “Because early detection andrapid intervention is essential in cases of sepsis, machine-learning toolslike this offer the potential to improve clinical outcomes in these infants,”said lead author Aaron Masino, PhD, of the department of biomedicaland health informatics.

Heart Failure Sensor cuts Hospitalizations in Half

H eart failure (HF) patients show a 58% reduction in hospitalization af-ter implantation of a pulmonary artery (PA) pressure measurement

sensor, claims a new study. The Abbott Vascular (Santa Clara, CA, USA;www.abbott.com) CardioMEMS Sensor is a permanently implantablewireless device that provides PA pressure measurements, including sys-tolic, diastolic, and mean pressures, which can used to monitor cardiacstatus and initiate changes in medical therapy if necessary.

Viscoelastic Heart Patch Treats Myocardial Infarction

a n adhesive epicardial patch could increase the mechanical integrityof damaged left ventricular tissues following a heart attack, claims a

new study. Developed by researchers at Brown University (Providence,RI, USA; www.brown.edu), Fudan University (Shanghai, China; www.fudan.edu.cn), Soochow University (Suzhou, China; www.suda.edu.cn),and other institutions, the ionically crosslinked transparent gel-point ad-

hesive patch (GPAP) is a viscoelastic material that combines both fluidand solid properties. The fluid properties are retained up to a certainamount of stress, at which point the material solidifies and turns stiffer,which can accommodate the cyclic deformation of the myocardium andleft ventricular remodeling following acute and subacute myocardial in-farction (MI).

contour System Reduces Functional Mitral Regurgitation

a n innovative device treats the primary cause of functional mitral re-gurgitation (FMR) by reshaping the anatomy and improving the

function of the mitral valve. The Cardiac Dimensions (Kirkland, WA,USA; www.cardiacdimesions.com) Carillon System is comprised of animplantable device and a proprietary percutaneous catheter delivery sys-tem that together provide a simple transcatheter mitral valve repair(TMVR) solution, by using a jugular vein access to reach the coronary si-nus under fluoroscopic guidance.

iPad System Programs Implanted Pacemaker Devices

a tablet-based management system provides portable and securewireless programming of implanted cardiac devices (ICDs). The

Medtronic (Dublin, Ireland; www.medtronic.com) CareLink SmartSyncdevice manager is a next-generation programmer and pacing system an-alyzer that features a simplified user interface, enhanced security, andBluetooth capabilities to communicate with compatible MedtronicBlueSync devices. The portable, wireless system allows physicians morefreedom to engage with patients as they program and manage cardiacdevices and device data. The SmartSync system includes the CareLinkSmartSync mobile application, a patient connector (telemetry head),and a base station (pacing system analyzer).






Smartphone-controlled Device Modulates Migraine Pain

a novel device worn on the upper arm uses smartphone-controlledelectronic pulses to relieve migraines through conditioned pain

modulation. The Theranica (Netanya, Israel; https://theranica.com) Ner-ivio Migra is indicated for the acute treatment of migraine-- with or with-out aura--in adults who do not have chronic migraine. The device con-sists of a programmable chip responsible not only for the electrical nervestimulation (ENS) and neuromuscular electrical stimulation (NMES) puls-es, but also incorporates features such as therapy efficiency control and asafety mechanism. The wireless device is first connected to a smartphoneapp; when instructed, it generates ENS and NMES pulses, which stimu-late subcutaneous sensory nerves via rubber electrode patches.

Hundreds of Medical Practices Are Ineffective or Misguided

a new study identifies almost 400 existing medical reversals, definedas low-value medical practices that are no better than a prior or less-

er standard of care. Researchers at the Oregon Health & Science Univer-sity (OHSU, Portland, USA; www.ohsu.edu), the University of Chicago(IL, USA; www.uchicago.edu), and other institutions undertook an analy-sis of more than 3,000 randomized controlled trials (RCTs) published inthree leading medical journals. Senior author Vinay Prasad, MD, said,“once an ineffective practice is established, it may be difficult to convincepractitioners to abandon its use. By aiming to test novel treatments rigor-ously before they become widespread, we can reduce the number of re-versals in practice and prevent unnecessary harm to patients.”

Donor kidney Transport System Preserves Organ FunctionA novel organ preservation and transport platform combines hypothermiaand ultrasound to provide optimal conditions during transfer of a trans-planted organ. Transplant Biomedicals’ (Barcelona, Spain; www.transplantbiomed.com) Vivian system is a single-use, disposable organ preser-vation device for kidney transport that is based on hypothermic ultra-sound preservation technology (HUPT), a revolutionary patented tech-nology that leads to superior preservation of organs during ex-vivo condi-tions. HUPT works by activating intrinsic protective mechanisms that aidcell survival and tissue regeneration pathways during injury, as well as in-ducing preservation energy metabolism and inflammatory response re-duction pathways.

bioelectronic Therapy Device exercises Heart Muscle

a novel electroceutical device readjusts the myocardial electrical gra-dient in order to strengthen the weakened heart muscle of car-

diomyopathy patients. Under development by Berlin Heals (Berlin, Ger-many; http://berlinheals.de), C-MIC cardiac microcurrent therapy isbased on an implanted pulse generator that exercises the heart muscleusing electricity, thus stimulating it to renew itself. In a minimally inva-sive procedure, a small microcurrent pulse generator is implanted via twosmall incisions. The system is designed to stimulate the affected heartmuscle, causing it to regenerate.

AI Aids Smart Devices to Detect cardiac Arrest

a new study reveals how a smart speaker can spot a heart attack bydetecting agonal breathing, a brainstem reflex that arises in the set-

ting of severe hypoxia. Developed by researchers at the University ofWashington (UW; Seattle, USA; www.washington.edu), the proof of con-cept tool is installed as an app into a smartphone or a support vector ma-chine (SVM) such as a Google Home or Amazon Alexa speaker in orderto monitor breathing and call for help if needed. Co-corresponding authorJacob Sunshine, MD, of the UW School of Medicine said, “cardiac arrestsare a very common way for people to die, and right now many of themcan go unwitnessed. Part of what makes this technology so compelling isthat it could help us catch more patients in time for them to be treated.”

new Device Improves Advanced Heart Failure Symptoms

a novel implant improves symptoms in patients with advanced heartfailure (HF) who are not suited for other HF devices. The CVRx

(Maple Grove, MN, USA; www.cvrx.com) Barostim Neo System is a sub-cutaneous, implantable device designed to electrically activate barorecep-tors in the carotid sinus in order to alleviate HF and high blood pressure.The system is indicated for patients who have a regular heart rhythm, are

not candidates for a cardiac resynchronization therapy (CRT) device, andhave a left ventricular ejection fraction (LVEF) of less than or equal to35% (below the normal ejection fraction of 55-75%).

Pulmonary Function Testing Platforms Advance Respiratory Diagnostics

t wo new innovative pulmonary function testing (PFT) systems provideuser friendly accessibility for both patients and technicians. The Vyaire

Medical (Chicago, IL, USA; www.vyaire.com) Vyntus ONE is designed tobe a convenient PFT station available in a fixed or mobile configuration.Vyntus ONE can also be expanded to do cardiopulmonary stress testing,creating a single device on minimal footprint. The Vyntus BODY systemconducts plethysmography exams with features similar to the Vyntus ONE,but can accommodate patients of all sizes and mobility in an all-glass testcabin with spacious interior space and a comfortable bench.

AVP cuts Trauma Transfusion needs in Half

G iving low-dose arginine vasopressin (AVP) to patients with traumaand hemorrhagic shock cuts the volume of blood products required

to stabilize them by half, according to a new study. A randomized studyby researchers at the University of Pennsylvania (Penn; Philadelphia, PA,USA; www.upenn.edu) and the Cleveland Clinic (CC; OH, USA; www.my.clevelandclinic.org) determined that low-dose supplementation ofAVP decreases the need for transfused blood products during resuscitation.

Sirolimus coated catheter clears Dysfunctional Hemodialysis Shunts

a novel balloon catheter treats stenotic arteriovenous fistula (AVF) orarteriovenous graft (AVG) vascular access anastomosis. The Concept

Medical (Tampa, FL, USA; www.conceptmedical.com) MagicTouch AVFSirolimus coated balloon catheter is indicated for use in percutaneoustransluminal angioplasty (PTA) of stenotic lesions of dysfunctional nativeAVF or AVG that are 4-12 mm in diameter and up to 100 mm in length.“Our preliminary data using the Magic Touch Sirolimus have been prom-ising to date, with an excellent safety profile and patient acceptability,”said consultant vascular and endovascular Surgeon Tjun Yip Tang, MD,of Singapore General Hospital.

AI Detects congestive Heart Failure From Single Heartbeat

a new study reports successful identification of severe chronic heartfailure (CHF) in 100% of cases using a single heartbeat recording

from an electrocardiogram (ECG). Researchers at the University of Surrey(Guildford, UK; www.surrey.ac.uk), the University of Warwick (Coven-try, UK; https://warwick.ac.uk), and The Organizational NeuroscienceLaboratory (OneLab; London, UK; www.theonelab.org) developed thenovel approach, which is based on artificial intelligence (AI). The tech-nique uses a convolutional neural network (CNN) data tree to detect datapatterns and structures at extremely high efficiency, which accuratelyidentifies CHF on the basis of one raw ECG heartbeat.

novel Anesthesia Monitor evaluates neuromuscular Transmission

a new portable neuromuscular transmission (NMT) monitor for useduring anesthesia features both acceleromyography (AMG) and

electromyography (EMG) modalities. The Xavant Technology (Pretoria,South Africa; www.xavant.com) Stimpod NMS450X monitor enables ob-jective NMT monitoring via AMG (with a reusable sensor) or EMG (witha disposable sensor) in order to manage patients undergoing neuromus-cular block during surgery, or in the intensive care unit (ICU).

new cryotherapy chamber Offers Healing and Restorative benefitsA novel whole-body cryotherapy chamber uses sub-zero temperatures tostimulate the circulatory, nervous, and energy systems within the body,prompting healing, recovery, and longevity. The CryoPod (Cumbria, UK;www.cryopod.com) Chamber includes a range of advanced technologies,including 100% breathable super-chilled air, built in Wi-Fi connectivity,state-of-the-art LCD touch screens, radiofrequency identification (RFID)card access, and a custom biometric monitoring system with displayscreens both within and outside the chamber in order to provide real-time users and staff information. The results can also be transferred andaccessed remotely to enable detailed analysis data of the client's experi-ence.

CRITICAL CARECRITICAL CARE Annual Review 2019Annual Review 2019



Integrated Airway System Reduces Ventilation complications

a comprehensive multi-purpose airway management system protectsthe lungs and tracheal tissues from infections and tissue injury. The

Hospitech Respiration (Kfar Saba, Israel; www.hospitech.co.il) Anapno-Guard system is designed to provide persistent monitoring of leaksaround an endotracheal tube (ETT) cuff and adjust cuff pressure automat-ically to ensure sealing at minimal pressure, minimizing induced pressureon the trachea tissue. In addition, the system evacuates subglottic secre-tions by simultaneous suction and rinsing. Isolation of the lower airwaysenables efficient lung ventilation and reduces the risk of aspiration aroundthe cuff and the consequential ventilator associated pneumonia (VAP).

next-Generation Patient Monitor Promotes Proactive care

a new vital signs monitor calculates risk-based alerts that allow clini-cians to identify subtle signs of patient deterioration. The Royal

Philips (Amsterdam, The Netherlands; www.philips.com) EarlyVue VS30vital signs monitor captures and displays patient data at the bedside, andsecurely transmits it directly into the hospital’s electronic medical record(EMR), supporting gap-free patient records. When conditions requirecloser attention, the VS30 can be switched from spot check to automatic(programmable) interval monitoring of critical vital signs such as nonin-vasive blood pressure, oxygen saturation (SpO₂), pulse, CO₂, and respi-ration rate. The monitor also includes Masimo (Irvine, CA, USA;www.masimo.com) rainbow SET options.

Suspended Animation Successfully Induced in Surgical Patient

F or the first time, a patient cooled by induced hypothermia has beensuccessfully revived, allowing surgeons more time to correct trau-

matic injuries. The new technique, which was developed at the Univer-sity of Maryland School of Medicine (Baltimore, USA; www.medschool.umaryland.edu), is called emergency preservation and resuscitation (EPR),and involves rapidly cooling a person suffering from acute trauma and car-diac arrest to around 10 to 15°C by replacing all of their blood with ice-cold saline. As the patient’s brain activity almost completely stops, theyare then disconnected from the cooling system and their body, whichwould otherwise be classified as dead, is moved to the operating theatre.

Vibro-Acoustic Air Pressure System clears the Airways

a novel technology removes secretions from the airways of patientssuffering from diseases affecting the respiratory tract. Developed at

BGN Technologies (Beer Sheva; Israel; www.bgu.ac.il) through a collab-oration between Ben-Gurion University (BGU; Beer Sheva, Israel; www.bgu.ac.il), Cincinnati Children's Hospital (OH, USA; www.cincinnatichildrens.org), and other institutions, the AeroSelf system simultaneouslyintroduces low-frequency, low-pressure, air flow oscillations and high fre-quency acoustic pulses into the airway and lungs. The system can treatthe core of obstructive airways pathophysiology diseases, the buildup ofmucus in the small airways, in a range of respiratory conditions, such asbronchiolitis, asthma, chronic obstructive pulmonary disease (COPD),and cystic fibrosis (CF).

Robotic entities could Improve Quality of Patient care

I ntroducing social and autonomous robotic health assistants (SARAs) toaid nurses interacting with patients could help overcome overwhelmingschedules and personnel reduction. The SARA consortium, led by BrightCape (Eindhoven, The Netherlands; https://brightcape.nl), Forum ViriumHelsinki (Finland; https://forumvirium.fi), GIM Robotics (Helsinki, Fin-land; https://gimrobotics.fi), the Technical University of Berlin (TUB; Ger-many; www.tu.berlin), and other institutions, is working to introduce ro-bots as largely autonomous social entities in nursing homes and hospitals.Using a system called SARA Home, the robots are accessible from a com-puter or tablet, allowing nurses to elaborate a personalized profile andhealth plan for every patient. SARA robots will be used assist patients com-plete specific exercises several times a week, helping them to improve theirmental and physical fitness. By interacting with the users and presentingthem with such simple exercises, their mental condition could be im-proved, helping to escape deterioration into the second, more acute stageof dementia. Two pilot tests are currently ongoing, in nursing homes in Fin-land and in the Netherlands.

CRITICAL CARECRITICAL CARE Annual Review 2019Annual Review 2019


embolization System Treats Intracranial Aneurysms

a novel intrasaccular flow disruptor helps surgeons achieve embolizationof intracranial wide neck bifurcation aneurysms. The MicroVention (Al-

iso Viejo, CA, USA; www.microvention.com) WEB aneurysm emboliza-tion system is an endovascular, intrasaccular solution for wide neck bifurca-tion aneurysms in the middle cerebral artery (MCA) bifurcation, the internalcarotid artery (ICA) terminus, the anterior communicating artery complex,the basilar artery apex, and any other saccular bifurcation intracranialaneurysm that has a dome diameter of three to 10 mm and a neck size offour 4 mm (or greater), or a dome-to-neck ratio between one and two.

Oxygenator Improves cardiopulmonary bypass care

a novel oxygenator helps minimize the impact of cardiopulmonary by-pass by reducing hemodilution, minimizing inflammatory response,

and providing highly efficient gaseous microemboli (GME) removal. TheTerumo Cardiovascular Group (Ann Arbor, MI, USA; www.terumo-cvs.com) Capiox NX19 Oxygenatorwith UltraPrime Technology is intend-ed for the exchange of gases betweenbloodcells and a gaseous environment,in order to satisfy the oxygenationneeds of adult patients during car-diopulmonary bypass surgery. An inte-grated arterial filter removes non-biologicparticles and emboli and facilitates airbubble removal from the blood flowingthrough the cardiopulmonary bypass cir-cuit. In addition, an integrated heat ex-changer is used to warm or cool bloodand/or perfusion fluid as it flows throughthe device.

novel knee System for Robot-Assisted Surgeries

a new platform for robot-assistedtotal knee replacement (TKR) fea-

tures pre-operative planning tools andintraoperative data to improve surgicalrestoration of natural joint movement.The Zimmer Biomet (Warsaw, IN,USA; www.zimmerbiomet.com) ROSAKnee System is a stereotaxic instru-mentation platform for TKR surgerydesigned to assist the surgeon by pro-viding software-defined spatial bound-aries for orientation and reference in-formation to identify anatomical struc-tures needed for the accurate place-ment of knee implant components.The core of the system includes a tac-tile robotic arm and three-dimensional(3D) visualization software that guidesthe surgeon during the procedure so asto conserve as much of the patient'shealthy bone and surrounding tissue aspossible.

Interventional cryotherapyPlatform Harnesses Liquidnitrogen

a new minimally invasive spraycryotherapy system treats the en-

tire spectrum of esophageal disease,from Barrett's Esophagus (BE) to cancer.The CSA Medical (Lexington, MA, USA;https://rejuvenair.com) truFreeze cryo-therapy system uses an extremely coldliquid nitrogen spray to flash-freeze anddestroy unwanted tissue in patients suf-fering from BE, esophageal cancer, andairway obstructions. The system also

enables tissue rejuvenation from underlying healthy tissue, in contrast tothe scar tissue that forms after heat-based modalities such as radio-fre-quency ablation (RFA).

Redesigned Mesh Sling System Treats Male Urinary Incontinence

a surgically implanted mesh sling system helps relieve stress urinary in-continence (SUI) in men by compressing and supporting the urethra,

helping the bladder to fully close. The Boston Scientific (Natick, MA, USA;www.bostonscientific.com) AdVance XP Male Sling System is designed toplace a SUI suburethral/retrourethral sling using a transobturator placementtechnique. Patients may be continent immediately after the procedure, andmost resume normal daily activities one to two weeks later. The sling itself,which acts as a hammock that repositions and supports the urethra, featuresa heat-sealed edge for fixation and a polypropylene liner that reduces pull-through resistance during sling passage, enabling desired sling placement pri-or to fixation.






Five Factors Linked to Infections Following Orthopedic Surgery

a new study links diabetes, obesity, smoking, prolonged surgery, and lowpre-surgical albumin levels to an increased risk of developing surgical

site infection (SSI). Researchers at Xinjiang Medical University (XJMU;Ürümqi, China; www.xjmu.edu.cn) and the First Hospital of Jilin University(Changchun, China; http://cie.jlu.edu.cn) conducted a retrospective studyinvolving 4,818 patients (60 years of age or older) who underwent electiveorthopedic surgery between January 2014 and September 2017. The resultsrevealed that 74 patients developed SSIs within one year, for an overall inci-dence rate of 3.64%.

Skin bioprinting System Helps Heal extensive wounds

a mobile skin bioprinter that layers dermal fibroblasts and epidermal ker-atinocytes directly into a wound can accelerate contraction and re-ep-

ithelialization, claims a new study. Developed at the Wake Forest Institute forRegenerative Medicine (WFIRM; Winston-Salem, NC, USA; https://school.wakehealth.edu), the mobile bioprinting system first isolates the ma-jor skin cells--dermal fibroblasts and epidermal keratinocytes-- from a smallbiopsy of uninjured tissue. The cells are then expanded and mixed into a hy-drogel and placed into the bioprinter. Using integrated imaging technologythe wound is then scanned; the data is used to direct the print heads onwhich cells to deliver exactly where in the wound, layer by layer.

Resistance-Sensing needle Identifies Target Destinations

a highly sensitive intelligent-injector for tissue-targeting (i2T2) needle candetect changes in resistance in order to properly and safely deliver med-

ication, claims a new study. Developed by researchers at the MassachusettsInstitute of Technology (MIT, Cambridge, MA, USA; www.mit.edu), HarvardMedical School (HMS; Boston, MA, USA; https://hms.harvard.edu), andBrigham and Women’s Hospital (BWH; Boston, MA, USA; www.brighamandwomens.org), the i2T2 intelligent injector is a highly sensitive,completely mechanical device that senses loss of tissue resistance when en-countering a softer tissue or a cavity, causing it to stop advancing the needleand deliver the payload. i2T2 feedback is instantaneous, which allows forbetter tissue targeting and minimal overshoot into an undesired location.

biologic Implant Regrows cartilage and bone

a novel cell-free biomaterial implant repairs cartilage and osteochondraldefects in both traumatic and osteoarthritic joints. The CartiHeal (Kfar

Saba, Israel; www.cartiheal.com) Agili-C implant is designed to provide ascaffold that reproducibly regenerates hyaline cartilage and its underlyingsubchondral bone in a single-step procedure. Once the size of the defect isdetermined, a cavity is prepared in the affected area and the implant is insert-ed in a press fit manner. Blood immediately infiltrates the implant’s intercon-nected pores, initiating a biological cascade culminating in bone and hyalinecartilage regeneration through migration, adhesion, proliferation, and differ-entiation of mesenchymal stem cells (MSCs). Within a few months, the toplayer turns into true hyaline cartilage, while the bottom layer turns to bone,with each tissue genetically identical to the body’s own tissues.

Orthopedic Drill Automatically Measures Depth and Power

a new surgical drill with a graphical user interface (GUI) provides real-time drill-bit location and drilling data for common orthopedic surgical

procedures. The Smart Medical Devices (SMD; Las Vegas, NV, USA; www.smartmeddevices.com) SMARTdrill 6.0 is a surgical drill accurately measuresdepth, torque, and energy in real time, improving patient outcomes. The de-vice’s accurate depth measurements eliminate the need for conventionaldepth gauges that plunge, reduce the number of times x-rays are needed, andenables surgeons to detect impending cortical and joint penetration at variedskive angles without the routine use of fluoroscopy. In addition, it eliminatesthe wasting of screws that were too long or too short during trial sizing.

Transcatheter bleeding Monitor Increases Patient Safety

a novel internal bleeding detector can improve bleed status monitoringduring and after endovascular access procedures. The Saranas (Hous-

ton, TX, USA; www.saranas.com) Early Bird Bleed Monitoring System in-cludes a vascular access sheath with embedded bioimpedance sensors thatare designed to detect and monitor bleeding from vessel injury, which mayoccur during endovascular procedures, such as a transcatheter aortic valvereplacement (TAVR), large bore hemodynamic support device placement, orother complex cardiovascular interventions where the femoral artery or veinis used to obtain vascular access. If the blood vessel is punctured, blood be-

gins to accumulate outside, causing a change in electrical impedance. Thesystem, which was designed and developed with the help of Cambridge Con-sultants (UK; www.cambridgeconsultants.com), can detect this change in re-al time and alert the physician; as there are no outward symptoms of such apuncture, the patient can bleed undetected.

Innovative Anchor System Fixates Sutures to bone

a new implanted anchor system helps orthopedic surgeons secure soft tis-sues to bone in order to facilitate faster healing. The Orthopaedic Im-

plant Company (OIC; Reno, NV, USA; www.orthoimplantcompany.com)OIC Suture Anchor System consists of implantable suture anchors and instru-ments to aid in their implantation, and is intended for the fixation of soft tis-sue to bone in support of a wide range of orthopedic procedures, includingupper extremity rotator cuff repair and biceps tendon reconstruction, andlower extremity lateral collateral ligament repair, medial collateral ligamentrepair, posterior oblique ligament repair, patellar tendon repair, and iliotibialband tendonesis joint capsule repair.

next-Generation Ablation System Treats Atrial Fibrillation

a third-generation technology platform uses laser ablation to perform pul-monary vein isolation (PVI), blocking the abnormal electrical pathways

that cause atrial fibrillation (AF). The CardioFocus (Marlborough, MA, USA;www.cardiofocus.com) HeartLight X3 System combines direct tissue visuali-zation, titratable laser energy, and compliant balloon technology to enableuninterrupted, high-speed, circumferential lesion creation under direct con-trol of the physician, resulting in consistently reduced procedure times. Thesystem is based on a near infrared (NIR) laser and a deflectable sheath thatprovides transseptal access to all four pulmonary veins.

Virtual Reality Platform Helps create Surgical Plans

a n innovative 360-degree virtual reality (VR) technology allows surgeonsto walk inside their patients' anatomy and create a surgical plan. The

Surgical Theater (Mayfield Village, OH, USA; www.surgicaltheater.net) Pre-cision VR medical visualization platform is designed to work on multiple lev-els of interaction with the aid of the Oculus Rift or HTC Vive VR headsets.The VR models are constructed and rendered based upon CT and MRI scans,culminating in a patient-specific 360° virtual tour which can be used to cre-ate an intuitive, immersive approach to patient engagement, surgical plan-ning, resident in training education, and multidisciplinary collaboration.

biologic-based Materials Aid Reconstructive Surgery

N ovel reconstructive materials support soft tissues in plastic and recon-structive surgery patients requiring repair or reinforcement. The TELA

Bio (Malvern, PA, USA; www.telabio.com) Restella reconstructive bioscaf-folds are based on a polymer interwoven through layers of biologic tissue ina patented "lockstitch" pattern, which creates a unique embroidered con-struction with controlled stretch that is highly permeable. The bioscaffoldscan support a variety of surgical techniques and procedures, with an empha-sis on ventral hernia repair and abdominal wall reconstruction.

Aortic Valve System Minimizes Paravalvular Leakage

a new transcatheter aortic valve replacement (TAVR) system for patientswith severe stenosis offers controlled delivery and repositionability. The

Boston Scientific (Natick, MA, USA; www.bostonscientific.com) LOTUSEdge aortic valve system features a proprietary braided Nickel-Titanium (Niti-nol) frame and an adaptive seal technology that conforms to patients’ anato-my in order to create a secure seal, virtually eliminating paravalvular leak(PVL). The deployment technology also allows easy retrieval, repositioning,and redeployment.

Perfusion System Increases Donor Lung Availability

a novel lung preservation system can temporarily ventilate, oxygenate,and perfuse lungs in order to better determine if they are viable for

transplant. The Xvivo Perfusion System (XPS) with STEEN Solution (XvivoPerfusion, Gothenburg, Sweden; www.xvivoperfusion.com) is intended tohouse donor lungs and preserve them prior to transplantation in patientswith end-stage lung disease. The system consists of the XPS perfusion cart,XPS cart software, and an cardiac bypass system with a centrifugal pump, aheater/cooler unit, and a ventilator. The system also includes STEEN solution,a sterile, non-pyrogenic, non-toxic physiological salt solution containing humanserum albumin and dextran, and fluid path and non-fluid path disposables.

Transseptal Access Dilator Facilitates LAA closure

a new dilation system with a larger diameter optimizes left-heart proce-dures that require a large sheath to cross the heart's septum from the

right atrium. The Baylis Medical (Montreal, Canada; www.baylismedical.

SURGICAL TECHNIQUESSURGICAL TECHNIQUESAnnual Review 2019Annual Review 2019

com) ExpanSure Transseptal Dilation System is intended for procedures suchas left-atrial appendage (LAA) closure and balloon ablation for atrial fibrilla-tion (AF). “Baylis is proud to offer a device uniquely designed to optimizetransseptal access, allowing the physician's primary focus to remain on deliv-ering the necessary therapy to the patient,” said Robert Harrison, director ofresearch and development in cardiology at Baylis Medical.

Ultrasonic Surgical Platform Integrates Minimally Invasive Therapeutics

a new ultrasonic surgical platform combines cutting, debridement, andaspiration tools into one unified system. The Misonix (Armingdale, NY,

USA; www.misonix.com) Nexus system includes BoneScalpel, a precision os-cillating tool designed for millimeter-wide cuts in bone while sparing sur-rounding soft tissue; the SonicOne attachment, which provides a debride-ment tool for cleaning wounds and removing damaged tissue or bacterialbiofilms; and the SonaStar ultrasonic aspirator, which removes targeted tis-sues, such as tumors. Stavros Vizirgianakis, President and CEO of Misonix.Said, “Nexus is a key component of our strategy to increase our presence inthe neuro, spine, ortho, wound, and general surgery markets.”

new Augmented Reality Surgical Platform Receives FDA Approval

a new augmented reality (AR) technology platform for surgical applica-tions has received 510(k) clearance for clinical use in the operating

room by the US Food and Drug Administration (FDA). The enterprise Surgi-calAR platform developed by medical technology company Medivis (NewYork, NY, USA; www.medivis.com) integrates the latest advancements in AR,artificial intelligence (AI), and computer vision to advance surgical visualiza-tion, thereby reducing surgical complications and improving patient out-comes while lowering costs for healthcare systems.

Decellularized Regenerative Device Supports cardiac Tissues

a novel epicardial patch supports the atria and the ventricular walls ofhearts that have been thinned or damaged as a result of myocardial in-

farct (MI). The CorMatrix (Rosewell, GA, USA; www.cormatrix.com) CorPATCH is designed to provide host cellular ingrowth and robust angiogenesisin support of adult epicardial structures post MI. It can also be used to treatsequelae secondary to MI that result in a thinning of the left or right ventric-ular walls, aneurysm formation, or for any other areas requiring a patch. TheCor PATCH is made of a multi-laminate sheet of decellularized lyophilizedextracellular matrix (ECM) derived from porcine small intestinal submucosa,which serves as a bioscaffold for vascular ingrowth from adjacent tissues.

biological Sealant Stems Moderate bleeding During Surgery

a n innovative airless spray delivers the clotting proteins fibrinogen andthrombin to stop bleeding when standard bleeding control techniques,

such as sutures, are impractical. The Ethicon Endo-Surgery (Ethicon; Cincin-nati, OH, USA; www.ethicon.com) Vistaseal Open and Laparoscopic dual ap-plicators (available in 35 cm and 45 cm lengths) combine biologics with de-vice technology to address mild to moderate surgical bleeding. The airlessspray products are the result of a broad partnership between Ethicon andplasma-derived medicine manufacturer Grifols (Barcelona, Spain). Thethrombin-catalyzed conversion of fibrinogen to fibrin consists of three re-versible steps, with thrombin being involved in only the first step, which is alimited proteolysis to release fibrinopeptides (FpA and FpB) from fibrinogento produce the fibrin monomer. In the second step, the fibrin monomers com-bine to form intermediate polymers through noncovalent interactions. In thethird and final step, the intermediate polymers aggregate to form the fibrinclot, which stems the bleed.

Vascular closure Device Seals Percutaneous entry Point

a n innovative closure device seals arterial puncture holes following per-cutaneous coronary intervention (PCI) catheter-based vascular proce-

dures. The Vasorum (Dublin, Ireland; http://vasorum.ie) Celt ACD is de-signed to close a femoral arteriotomy following intra-arterial procedures, suchas peripheral or coronary angiography, arterial stents, balloon angioplasty, anddiagnostic or interventional catheterization procedures involving the com-mon femoral artery.

Focal Laser Therapy Destroys breast Tumors

a minimally invasive procedure uses laser induced heat for focal destruc-tion of breast fibroadenomas and tumors of up to two centimeters in

size. During the procedure with the Novian Health (Chicago, Il, USA;https://novianhealth.com) Novilase Laser Therapy System ultrasound or x-ray image-guidance is used to insert the two small probes into and alongsidethe tumor. The laser probe delivers laser energy to provide focal thermal en-ergy, while the thermal probe monitors temperature at the edge of the de-sired ablation zone. Studies have shown that more than 90% of malignantbreast tumors are completely destroyed during one Novilase procedure, withpatients reporting better health-related quality of life outcomes compared tolumpectomy.

Integrated Technology Platform Improves Spine Surgery

a n innovative multiple technology operating room (OR) platform helpssurgeons adopt a more efficient and less disruptive minimally invasive

surgery (MIS) approach in all spine procedures. The NuVasive (San Diego,CA, USA; www.nuvasive.com) Pulse OR platform combines neuromonitor-ing, surgical planning, rod bending, radiation reduction, and imaging andnavigation functions to improve operative workflow, reduce variability andincrease surgical reproducibility. Independent device access allows OR staffto view the various technologies' imaging and insights, simultaneously and inreal time.

Machine Learning Approach Predicts Surgery Duration

a novel artificial intelligence (AI) based statistical model uses large retro-spective datasets to improve estimation of surgical procedures duration.

Researchers at the University of Washington (UW; Seattle, USA; www.washington.edu) and Perimatics (Bellevue, WA, USA; www.perimatics.com) useda dataset that included nearly 47,000 scheduled surgeries performed by 92surgeons at UW between January 2014 and December 2017 in order to de-velop, test, and train machine learning (ML) statistical models that could im-prove operating room (OR) efficiency by better predicting case-time duration.



new catheter Simplifies Persistent AF cryoablation

a novel persistent atrial fibrillation (PsAF) cryoablation catheter that reliesmostly on anatomical markers eliminates the need for electromagnetic

mapping. The Adagio Medical (Laguna Hills, CA, USA; https://adagiomed-ical.com) One Shot+ cryoablation catheter is intended for pulmonary veinisolation (PVI) and other continuous ablation lesions of non-pulmonary-vein targets, using a transseptal procedure to create continuous and focaltransmural lesions on the left and right atrium. The catheter incorporatesdiagnostic electrodes for navigation to the ablation site and real-time mon-itoring of electrograms to confirm lesion creation and only requires a singletransseptal puncture to reach the targets in the left atrium.

Spinal Tether Device Treats Idiopathic Scoliosis

a n innovative spinal tether device corrects idiopathic scoliosis in chil-dren and adolescents who fail to respond to conservative treatment

options, such as external bracing. The Zimmer Biomet (Warsaw, IN, USA;www.zimmerbiomet.com) Tether vertebral body tethering (VBT) system isintended to provide an alternative to growing children and adolescentswith idiopathic scoliosis that do not respond to bracing, and whose spinalcurves are approaching or have reached the range where surgical treatmentis an option. The system includes anchors, vertebral body screws, andsetscrews made of titanium alloys that are placed into the same side of eachvertebra in the curved section of the spine through an incision on the sideof the chest. Idiopathic scoliosis is a sideways curvature of the spine whosecause is unknown. It is the most common spinal deformity in children,most often diagnosed between ages 10 to 18.

breakthrough coronary Sinus Device Improves Myocardial FunctionA novel intermittent occlusion device helps reduce infarct size and im-prove cardiac function following an acute myocardial infarction (AMI). TheMiracor Medical (Awans, Belgium; www.miracormedical.com) PiCSO Im-pulse System consists of a balloon tipped triple-lumen catheter and a driveconsole. The system and concomitant therapy is based on the fact thatcoronary sinus pressure increases when the vessel is occluded and drainageof venous blood into the right atrium is inhibited. As a result, during theocclusion period, normal right atrial blood pressure builds up to reach apressure plateau, without effecting systemic arterial pressure. The risecauses an increase in arterial wedge pressure over the ischemic area.

wound closure System Outperforms Staples and Sutures

a novel skin closure system reduces incision-related problems, providesgreater range of motion, reduces pain, and results in superior scar

quality. The ZipLine Medical (Campbell, CA, USA; www.stryker.com) Pre-placement RE-aligning LOw-tension Closure (PRELOC) system is a non-in-vasive and easy-to-use skin closure device that replaces sutures, staples,and glue for surgical incisions and lacerations. A breathable monofilm base,which is applied before the incision, facilitates re-approximation of incisionedges. Once the zipped tags are pulled, tension in the surrounding skin isbridged over and around the incision, resulting in a low-tension and uni-form distribution of closure forces, unlike point load forces typical of staplesand sutures. Since no skin piercing is involved, there is a reduced risk ofsurgical site infection (SSI) and needle stick injury.

Orthopedic Robotic System Facilitates external Fixation

a smart, robotic external fixation system addresses the two major chal-lenges facing physicians, patient compliance and lack of real-time

feedback. The OrthoSpin (Misgav, Israel; www.orthospin.com) AutoStrutsystem is an external fixator based on the DePuy Synthes (West Chester,PA, USA; www.jnjmedicaldevices.com MaxFrame multi axial correctionsystem, including all its parts and software; but with the six MaxFramestruts substituted by length-adjustable motor-powered AutoStruts. UsingMaxFrame 3D planning software, an accurate treatment plan is generatedvia advanced algorithms, eliminating the need for manual measurement,reducing procedural complexity, radiation exposure, overall costs, andtreatment time.

Rotatable Heart Valve Treats babies and Toddlers

a n innovative pediatric mechanical heart valve provides a new treat-ment option for newborns, infants, and toddlers in need of a mitral or

aortic valve replacement. The Abbott (Abbott Park, IL, USA; www.abbott.com) Masters HP 15mm rotatable mechanical bileaflet heart valve is de-signed to mimic the valve functions of a healthy heart, opening and closingwith each heartbeat and assuring proper blood flow. The valve, which can

be implanted in either the mitral or aortic position, includes pyrolytic car-bon leaflets and orifice rings that provide an 85 degree leaflet opening an-gle to reduces turbulence, and a controlled torque rotation mechanism forintraoperative adjustment. A sewing cuff contains additional suture mark-ers for more accurate placement.

3D-Printed Interbody Implants Facilitate bone Fusion

a n innovative portfolio of three-dimensional (3D) printed titanium in-terbody implants are designed to treat degenerative spine disease by

expediting fusion surgery. The DePuy Synthes (West Chester, PA, USA;www.jnjmedicaldevices.com) CONDUIT Interbody Platform with EIT Cel-lular Titanium Technology provides the fabricated structures with a poros-ity of 80%, which closely mimics the structure and modulus of elasticity ofnatural human cancellous bone. During the spinal fusion procedure, thedegenerated, collapsed disc is removed and replaced with a CONDUIT in-terbody spacer, along with a bone graft, with the intention of restoring nat-ural height and alignment between two adjacent vertebrae. The interbodyimplant is also prepared with roughened nanoscale surface features that tolead to increased adhesion of osteoblasts, compared to conventional titani-um materials. The end result is that the formerly mobile disc space be-tween the two vertebrae fuses into as a single, solid bone.

new Polymer Heart Valve Implanted in First Human Patient

N ext-generation implantable biopolymer heart valves last longer, arecheaper to manufacture and are more biocompatible than currently

available options. Developed at the California Institute of Technology (Cal-tech; Pasadena, USA; www.caltech.edu) and manufactured by Foldax (SaltLake City, UT, USA; https://foldax.com), the Tria heart valve combinesLifePolymer, an advanced biopolymer material, and a patented bioinspireddesign in order to create a heart valve capable of lasting for decades with-out calcification, risk of clotting, or damage to red blood cells (RBCs). Dur-ing testing, one valve has already lasted for 600 million cycles, the equiva-lent of around 15 years, without signs of significant wear and tear.

Implantable Duodenal Liner Improves Insulin Resistance

a new device that combines an intragastric balloon with a connectingsleeve mimics the effects of traditional bariatric surgery on people

with obesity and Type 2 diabetes (T2D). Developed at Sapienza University(Rome, Italy; www.uniroma1.it), Università Cattolica del S. Cuore (UCSC;Rome, Italy; www.unicatt.it), King’s College London (KCL; UK;www.kcl.ac.uk), and other institutions, the Sleeveballoon device consistsof an intra-gastric balloon with a central channel to allow passage of foodinto the proximal small bowel, which is then covered by a sleeve that ex-tends into the duodenum and proximal jejunum. This reduces gastric vol-ume by 2/3, while the sleeve bypasses the proximal small bowel, deliver-ing food directly to the mid-jejunum. The device is intended for use for aperiod of 12-18 months.

Smart navigation Systems Optimize Total Hip Arthroplasty

t he combination of two surgeon-controlled surgical planning and guid-ance platforms optimizes the treatment of total hip arthroplasty (THA)

procedures. The EOS Imaging (Paris, France; www.eos-imaging.com)hipEOS 3.0 is a three dimensional (3D) surgical planning solution that usesweight-bearing standing and sitting EOS images and 2D/3D patient-specif-ic models and datasets to help select and position implants for the bestanatomical fit in order to optimize range of motion, based on each patient’s3D anatomy. This delivers an optimal surgical strategy while taking intoconsideration patient-specific factors that are key criteria for successfulTHA, including hip-spine relationship, leg length discrepancy, femoral off-set and femoral torsion.

3D-Printed Implant Supports Lateral Spinal Fusion

a novel lateral expandable fusion device allows surgeons to achieve up to30 degrees of sagittal spinal correction in skeletally mature patients.

The Stryker (Kalamazoo, MI, USA; www.stryker.com) SAHARA Lateral 3DExpandable Interbody System uses a passive expansion mechanism that canbe intraoperatively adjusted from a lateral approach, or passively adjusted ina staged posterior approach following an osteotomy. SAHARA Lateral is avail-able in a variety of footprints, heights, and lordotic offerings so as to more pre-cisely match a patient's anatomy. The system is intended for use with supple-mental fixation systems, such as the SAHARA anterior lumbar expandablestabilization system, a lordotic device with integrated screw fixation.


SURGICAL TECHNIQUESSURGICAL TECHNIQUES Annual Review 2019Annual Review 2019


17 HospiMedica InternationalJune-July/2020 117HMI-07-20LInkXPReSS cOM

new Imaging Device Identifies Parathyroid Glands During Surgery

a new device that uses autofluorescence imaging to identify theparathyroid glands reduces the incidence of post-thyroidectomy

hypocalcemia. The Fluoptics (Grenoble, France; www.fluoptics.com) Flu-obeam LX is exclusively dedicated to thyroid and parathyroid surgery thatdetects the parathyroid gland by autofluorescence in the near-infrared (nIR)light band, with the aid of an optimized real-time display, a high depth offield, and compatibility with ambient operating room lights. Handheld andeasily manipulated to cover the surgical field, Fluobeam LX offers an opti-mized ergonomics with a joystick that simplifies the navigation and selec-tion of the software functionalities, directly by the surgeon.

novel Technology Provides Real-Time Perfusion MonitoringA new monitoring system offers real-time perfusion feedback, enhancingclinician’s decision-making in the angiography suite. The Pedra Technology(Singapore; www.pedratech.com) Pedra system is a non-invasive, deep tis-sue, real-time tissue perfusion monitor intended for use in peripheral angio-plasty and vascular surgery. The device is based on advanced speckle lasertechnology, providing a simple five-minute, non-invasive test to distinguishbetween ischemic ulcers resulting from peripheral vascular disease (PVD)and neuropathic diabetic foot ulcers (DFUs). The resulting Pedra Blood Per-fusion Index can indicate the need for urgent vascular surgery.

Therapeutic Device Reduces Postoperative Oxygen Desaturations

p eripheral stimulation technology reduces postoperative hypoxemia(oxygen desaturation) in patients at-risk for obstructive sleep apnea

(OSA). The MediPines (Orange County, CA, USA; www.medipines.com)Oxistimulator is a novel peripheral transcutaneous electrical stimulus (TES)device placed on the wrist that is designed to continuously monitor patientoxygenation levels and to reduce desaturations automatically whendeemed necessary. Whenever threshold oxygen saturation (SpO2) levelsare lower than 93%, the Oxistimulator provides an immediate mild electri-cal stimulation, a therapeutic response that is just strong enough to reversethe deterioration, without harm or discomfort to the patient.

new System Facilitates Tympanostomy Tube Delivery

a n innovative tympanostomy (ear tube) delivery system enables place-ment of tubes in the comfort of an office environment. The Tusker

Medical (Menlo Park, CA, USA) Tubes Under Local Anesthesia (Tula) sys-

tem is designed to enable delivery of an ear tube to patients under localanesthesia in a physician's office setting, obviating the need for generalanesthesia. The system is composed of four concentric components thatcut, dilate, shield, and stabilize. The cutter first creates the myringotomy;the dilator opens the incision, while the shield introduces the tympanosto-my tube through the myringotomy. The system is approved for use in bothadults and children as young as six months of age.

balloon Dilation effectively Treats Sleeve Gastrectomy Stenosis

e ndoscopic balloon dilation (EBD) appears to be a safe, minimally inva-sive alternative to surgical revision for sleeve gastrectomy stenosis

(SGS), according to a new study. Researchers at NYU Langone MedicalCenter (New York, NY, USA; www.med.nyu.edu) and Brigham andWomen's Hospital (BWH; Boston, AM, USA; www.brighamandwomens.org) conducted a systematic review and meta-analysis of studies throughJuly 2018 that examined the influence of EBD for SGS. The primary out-come was defined as overall success rate of clinical resolution of SGS ob-structive symptoms with EBD; secondary outcomes included EBD successrates for SGS in proximal or mid-distal location in early and late SGS, andsuccess rate of cases requiring stents or salvage surgery.

FDA to establish Oversight Rules for AI in Medicine

t he US Food and Drug Administration (FDA; Silver Spring, MD, USA;www.fda.gov) is developing a framework for regulating artificial intelli-

gence (AI) products used in medicine that continually adapt based on newdata.In a white paper published in March 2019, the FDA details the criteriathe agency proposes for rules that will be used to determine when and ifmedical products that rely on AI will require FDA review before being com-mercialized. The FDA review may include examination of the underlyingperformance of a product’s algorithms, a manufacturer’s plan to make modi-fications, and the manufacturer’s ability to manage the risks associated withany modifications.

Drone Delivery System Transports Samples between Hospitals

S wiss Post (Bern, Switzerland; www.post.ch) is laying out a drone deliv-ery system to convey laboratory samples between hospitals that will ar-

rive function twice as fast as road transport. A pilot study, carried out in col-laboration with the Federal Office of Civil Aviation, Skyguide, which moni-tors Swiss airspace, and local authorities, will use the drones to transport

urine and blood samples five to ten times a day between University HospitalZürich (USZ; Switzerland; www.en.usz.ch) and the USZ Irchel campus,which are 2.5 kilometers apart. The time savings are expected to help pa-tients, for example those under anesthesia, waiting for laboratory results.

Facial Recognition continuously Monitors IcU Patients

a new study evaluates an automated system that uses facial recognitiontechnology to continuously monitor the safety of patients admitted to

the intensive care unit (ICU). Developed by researchers at Yokohama CityUniversity (Japan; www.yokohama-cu.ac.jp), the system uses ceiling-mount-ed cameras placed above the patients' beds. After collecting about 300 hoursof daytime image data of patients facing the camera in body positions thatshowed their face and eyes clearly, 99 images were subject to a machine-learning (ML) algorithm to analyze them. Based on input from the observa-tional data, especially from around the subject's face, the ML algorithmlearned to identify potential high-risk behavior in a process that resembles theway a human brain learns new information.

Augmented Reality Perceives Real-Time Pain of Patients

a novel augmented reality (AR) platform combines visualization with neu-roimaging to help clinicians map patient pain in real-time. Developed at

the University of Michigan (U-M; Ann Arbor, USA; https://umich.edu), theportable clinical augmented reality and artificial intelligence (CLARAi) isbased on a sensor-outfitted cap that detects changes to blood flow and oxy-genation using functional near-infrared (nIR) spectroscopy. The data is decod-ed using a neural network (NN) algorithm to classify the hemodynamic re-sponse data into color-coded pain and no-pain brain states. At the same time,clinicians wear a Microsoft HoloLens AR glasses, which allows them to viewbrain activity in real time on a reconstructed brain template, while the sub-jects sit in a clinical chair.

Apple Opens iPhone eHR Feature to US Healthcare Organizations

a pple will allow any healthcare organization with a compatible electronichealth record (EHR) to register with its mobile Health Records feature,

which will allow users to securely and privately download their data to a per-sonal health record (PHR) on their iPhone. Compatible EHRs are based onFast Healthcare Interoperability Resources (FHIR), a standards framework forexchanging clinical data over the Internet. There are currently about 300healthcare organizations, labs, and clinics (with over 6,500 locations acrossthe United States) that have registered in the Apple Health Records directoryin the Health app. The EHRs that Apple currently supports include Epic,Cerner, athenahealth, and CPSI, which are capable of plugging into the PHRapp. Patients can download their EHR after presenting their credentials to thepractice or a hospital patient portal.

Digital Avatar Helps Plan Personalized Therapies

a virtual doppelganger that is programmed with a patient’s physiologicaldata could aid in providing a personalized prognosis of treatment. Un-

der development at the Swiss Federal Laboratories for Materials Science andTechnology (Empa; Dübendorf, Switzerland; www.empa.ch), the digital twinrepresents a complex multi-physical skin model fed with data from non-inva-sive sensor systems attached to the human skin. The ostensible transdermalmanikin and a linked-up computer model are then used to simulate humanphysiological responses to drugs and medicines, such as changes in skin tem-perature or perspiration rate, which can then be analyzed in order to enableprecise and personalized dosage of the active agents.

nanodrone Detects Toxic Gases in Hazardous environments

a new study describes an innovative smelling nano aerial vehicle (SNAV)that can detect dangerous compounds in buildings that have collapsed

due to earthquakes or explosions. Developed at the University of Barcelona(UB, Spain; www.ub.edu), the Institute for Bioengineering of Catalonia(IBEC; Barcelona, Spain; www.ibecbarcelona.eu) and Örebro University(ORU; Sweden; www.oru.se ), the SNAV nanodrone weighs just thirty-fivegrams, including two nanometric metal oxide semiconductor (MOX) gas sen-sors that can respond to carbon monoxide (CO), methane (CH4), and otherorganic volatile compounds such as ethanol, acetone and benzene, with a de-tection threshold on the order of one part per million in volume (PPMV), ac-cording to the gas and the sensor used.




Annual Review 2019Annual Review 2019Health IT

China • ChengduTel: (86) [email protected] Medical Imagingspain • BarcelonaTel: (34) [email protected] SourceUsa • Milwaukee, WITel: (1) [email protected] Apparecchi MedicalItaly • BolognaTel: (39) [email protected] DiagnosticsUsa • orlando, FlTel: (1) [email protected] TechnologyChina • shenzhenTel: (86) [email protected] • BallerupTel: (45) [email protected] TechnologyChina • shenzhenTel: (86) [email protected] TechnologiesUsa • los angeles, CaTel: (1) [email protected] MedicalEndoscopyUsa • Miami, FlTel: (1) [email protected]

AmicoCanada • richmond HillTel: (1) [email protected] • seoulTel: (82) [email protected]

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AnalogicUsa • Peabody, MaTel: (1) [email protected] AidUK • BradfordTel: (44) [email protected] MedUK • GranthamTel: (44) 01476-516-200angelmed.co.ukAnke High-Tech Co.China • shenzhenTel: [email protected] China • shenzhenTel: (86) [email protected] MedicalTaiwan • new Taipei CityTel: (886) 2-2268-5568apexmedicalcorp.commarketing@apexmedical.com.twARCOMAswitzerland • KlotenTel: (46) [email protected] MedicalSystems

switzerland • regensdorfTel: (41) [email protected] • MalmöTel: (46) 10-335-4500arjo.comArmstrongMedical IndustriesUsa • lincolnshire, IlTel: (1) 847-913-0101armstrongmedical.comintl@armstrongmedical.comArticomedPoland • WroclawTel: (48) [email protected] LaserTechnologiesGermany • JenaTel: (49) 3641/[email protected] • ZabierzowTel: (48) [email protected] MedicalA Hill-Rom Company

Usa • Caledonia, MITel: (1) 616-698-7100aspensurgical.comcustomerservice@as-pensurgical.comAssut Suturesswitzerland • lausanneTel: (41) [email protected] • anyangTel: (82) [email protected] SpecialityLightingUsa • Hialeah, FlTel: (1) [email protected] MedizintechnikGermany • lenzkirchTel: (49) 7653-6890

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Action ProductsUsa • Hagerstown, MdTel: (1) 301-797-1414actionproducts.comservice@actionproducts.comADANIBelarus • MinskTel: (375) [email protected] • Buenos airesTel: (54) 11 4481 [email protected]

AdvancedInstrumentationsUsa • Miami, FlTel: (1) [email protected] Europe netherlands • Breda Tel: (31) [email protected] InternationalMedicalUsa • Temecula, CaTel: (1) [email protected] ProTaiwan • Changhua CityTel: (886) [email protected] TechnologyChina • shenzhenTel: (86) [email protected] • BeijingTel: (86) [email protected] MedicalSystemsIsrael • Holon

Tel: (972) [email protected] IndustriesUsa • College Point, nYTel: (1) [email protected] Industries, Filtration GroupUsa • st. louis, MoTel: (1) [email protected] HealthcareBelgium • MorstelTel: (32) [email protected] GommaItaly • BolognaTel: (39) [email protected] • Melbourne, FlTel: (1) [email protected] • VilniusTel: (370) [email protected] Projects Germany • nattheimTel: (49) 7321 730 [email protected] • abbott Park, IlTel: (224) 667-6100abbott.comAllgaier InstrumenteGermany • Frittlingen/TuttlingenTel: (49) 7426-9615-0allgaier-instrumente.deinfo@allgaier-instrumente.deAllTech Medical Systems

although all material in this directory is compiled from sources believed reliable, pub-lisher cannot be held liable for any errors, omissions or inaccuracies. Inclusion, orlack of it, in this directory, does not constitute any endorsement or expression of oth-er opinion by publisher with regard to companies, their products or services.


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Celitron MedicalTechnologiesHungary • VácTel: (36) [email protected] SurgicalPakistan • sialkotTel: (92) 52-320-6525surgical@centralsurgical.comcentralsurgical.comCharmcareKorea • seoulTel: (82) [email protected] IndustriesUsa • Ball Ground, GaTel: (1) 770-721-8800chartindustries.comCheirónCzech republic •PragueTel: (42) [email protected] • nanjingTel: (86) [email protected] MedicalChina • BeijingTel: (86) [email protected] • HeidelbergTel: (49) [email protected] Medical ImagingChina • WuxiTel: (86) [email protected] HealthcareUsa • Miami, FlTel: (1) [email protected] • Pittsburgh, PaTel: (1) [email protected]

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DeltronixBrazil • ribeirao PretoTel: (55) 16-4009-5454deltronix.com.brdeltronix@deltronix.com.brDemetechsweden • TäbyTel: (46) [email protected] • Powell, TnTel: (1) [email protected] Lichtswitzerland • GossauTel: (41) [email protected] MedicalUK • aylesbury, BuckinghamshireTel: (44) [email protected] • Webb City, MoTel: (1) [email protected] Medical Device Technologyargentina • Buenos airesTel: (54) [email protected] ItaliaItaly • Bologna Tel: (39) [email protected] • WiesbadenTel: (49) [email protected] IndustrialChina • ChangchunTel: (86) [email protected] InternationalUsa • lewisville, TX Tel: (1) [email protected] ImagingFrance • MontpellierTel: (33) [email protected]

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Greiner Bio-Oneaustria • KremsmuensterTel: (43) [email protected]

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Hitachi HealthcareJapan • TokyoTel: (81) 422-45-6049hitachi.com/healthcareHMB EndoscopyProductsUsa • davie, FlTel: (1) [email protected] • Marlborough, MaTel: (1) [email protected] ElectronicsJapan • Toyohashi CityTel: (81-532) [email protected] AidsUK • northamptonTel: (44) 0-1604-586-501hospitalaids.co.ukinfo@hospitalaids.co.ukHumanmeditekKorea • seoulTel: (82) [email protected] HealthcareUK • CardiffTel: (44) 29-2048-5885huntleigh-diagnostics.comsales@huntleigh-diagnostics.co.ukHuqiu ImagingChina • suzhouTel: (86) [email protected] • Patterson, nYTel: (1) [email protected] Medical EquipmentChina • shenzhenTel: (86) [email protected] • seoulTel: (82) [email protected] Watson Health Usa • Chicago, IlTel: (1) 312-565-6868

ibm.com/watson-healthiCADUsa • nashua, nHTel: (1) [email protected] • Goleta, CaTel: (1) [email protected] MedicalUsa • san Clemente,CaTel: (1) [email protected] • TokyoTel: (81) 3-5700-1111ikegami.com

ILO ElectronicGermany • QuickbornTel: (49) [email protected] • elmsford, nYTel: (1) 914-592-6100imageworkscorporation.comcustserv@imageworkscorporationImaging DiagnosticSystemsUsa • Ft. lauderdale, FlTel: (1) [email protected] DynamicsCanada • Calgary, aBTel: (1) [email protected] SpecialistsUsa • Miami, FlTel: (1) 305-591-8888tisg.netImaxeonaustralia • rydalmere,nsWTel: (61) [email protected] Medicalswitzerland • BuchsTel: (41) [email protected] • seoulTel: (82) [email protected]

Infinium MedicalUsa • largo, FlTel: (1) 727-531-8434infiniummedical.comsales@infiniummedical.comIngenieria Y Tecnicas Clinicasspain • MadridTel: (34) [email protected] • suzhouTel: (86) 512-8766-3622innolcon.comInnomed MedicalHungary • BudapestTel: (36-1) [email protected]

Inomed MedizintechnikGermany • emmendingenTel: (49) [email protected] HealthcareUK • CrawleyTel: (44) 0-1455-840-555inspiration-healthcare.cominfo@inspirationhealthcare.comInstramedBrazil • Porto alegreTel: (55) [email protected]

InteleradCanada • Montreal, QCTel: (1) 514-931-6222intelerad.comINTERmedicspain • BarcelonaTel: (34) 932-656-661inter-medic.net [email protected] BiomedicalUsa • austin, TXTel: (1) [email protected] • Wokingham, BerkshireTel: (44) [email protected]

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Jai SurgicalsIndia • GurgaonTel: (91) [email protected] Honigberg InternationalUsa • deerfield, Il Tel: (1) 847-412-0200jdhintl.com [email protected] • Hayward, CaTel: (1) [email protected]

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China • XuzhouTel: (86) [email protected] ABsweden • BrommaTel: (46) [email protected] Medical DevicesTurkey • ankaraTel: (90) [email protected]

Karl Otto BraunGermany • WolfsteinTel: (49) [email protected] • BeijingTel: (86) [email protected] • Harlow, essexTel: (44) [email protected] & SohnGermany • BalingenTel: (49) [email protected] MedicalEquipmentChina • XuzhouTel: (86) [email protected]@kernelmed.comKimalUK • WorcesterTel: (44) [email protected] Medical EquipmentChina • GuangzhouTel: (86) [email protected] Martin Group Germany • TuttlingenTel: (49) [email protected] Medicalnew Zealand • aucklandTel: (64) [email protected] Minolta Medical & Graphic

Imaging EuropeGermany • langenhagenTel: (49) [email protected] DevelopmentUsa • Jensen Beach, FlTel: (1) [email protected] Medical SystemsUsa • Chester, nYTel: (1) 845 [email protected] TechnologyUsa • st. louis, MoTel: (1) [email protected] UltrasoundUsa • Yorba linda, CaTel: (1) [email protected] Digital X-RayUsa • stratford, CTTel: (1) [email protected] MedicalUsa • Miami, FlTel: (1) [email protected] Medical norway • stavangerTel: (47) [email protected] MedicalChina • shenzhenTel: (86) 755 [email protected] - AB Medica Groupspain • BarcelonaTel: (34) [email protected] • WaalwijkTel: (31) [email protected] Medicaldenmark • Glostrup




Ferno fernointernational.comFinapres Medical systems finapres.comFirst Medical International firstmedus.comFisher & Paykel Healthcare fphcare.comFlaem nuova flaemnuova.itFlexicare Medical flexicare.comFresenius Kabi fresenius-kabi.comFukuda denshi fukuda.co.jpFuturemed futuremed.comGaleMed Corporation galemed.comGe Healthcare gehealthcare.comGeneral Biomedical service generalbiomedical.comGeneral Meditech szmedtech.comGinevri ginevri.comGMMC gmmc-inc.comGreiner Bio-one vacuette.comGrifols grifols.comGuided Therapeutics guidedinc.comGulf Fiberoptics gulffiberoptics.comHamilton Medical hamilton-medical.comHans rudolph rudolphkc.comHard Manufacturing hardmfg.comHarloff harloff.comHeal Force healforce.comHeartland Medical heartlandmedical.comHeartsine Technologies heartsine.comHeine optotechnik heine.comHersill hersill.comHeyer Medical heyermedical.deHillusa hillusa.comHuntleigh huntleigh-diagnostics.co.uki-sens i-sens.comiCrco icrco.comICU Medical icumed.comImaxeon imaxeon.comIMT Medical imtmedical.comInfinium Medical infiniummedical.comIngenieria Y Tecnicas Clinicas itcsal.comInnomed Medical innomed.huInomed Medizintechnik inomed.comInspiration Healthcare inspiration-healthcare.comInstramed instramed.com.brInternational Biomedical int-bio.comIntersurgical intersurgical.comInvacare invacare.comJadaK jadaktech.comJd Honigberg International jdhintl.comJMs jmsna.netJumper Medical equip. jumper-medical.comJW Medical jw-medical.co.krKanmed kanmed.seKare Medical devices karemedical.euKellyMed kelly-med.comKern & sohn kern-sohn.comKernel Medical kernelmed.comKimal kimal.co.ukKM Medical kmmedical.co.nzKorU Medical systems korumedical.comKoven Technology koven.comKX Medical kxmedical.comlaerdal Medical laerdal.comlandwind Medical landwindmedical.comlessa - aB Medica Group lessap.comlMT Medical systems lmt-medicalsystems.comlode lode.nllodox system lodox.comlutech lutechmedical.comMagnamed Tecnologia Medica magnamed.com.brMaltron International maltronint.comMasimo masimo.comMaxtec maxtec.comMed-link electronics med-linket.comMedcaptain Medical Technology medcaptain.com

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Critical Care


[email protected] HealthcareIndia • MumbaiTel: (91) [email protected] • High Wycombe,BuckinghamshireTel: (44) [email protected] • ouluTel: (358) [email protected] Belgium • sorinnesTel: (32) 82 22 30 [email protected] • doral, FlTel: (1) [email protected] • Gaithersburg, MdTel: (1) [email protected] • stutenseeTel: (49) [email protected] • daejeonTel: (82) [email protected] • ribeirao PretoTel: (55) 16-3238-0300medpej.ind.brmedpej@medpej.com.brMedsetMedizintechnikGermany • HamburgTel: (49) [email protected] • GemblouxTel: (32) [email protected] • Minneapolis, MnTel: (1) 763-514-4000medtronic.com

MedvixUsa • Irvine, CaTel: (1) [email protected] • PajuTel: (82) [email protected] ElectronicEquipmentChina • MianyangTel: (86) [email protected] MedicalIsrael • YavneTel: (972) [email protected] MedicalUsa • Clearwater, FlTel: (727) 573-0088mercurymed.comInternationalCustomerservice@mercurymed.comMerivaaraFinland • lahtiTel: (358) [email protected] MedicalUK • rhymney, WalesTel: (44) [email protected] LaboratoriesUsa • lakewood, CoTel: (1) [email protected] MedizintechnikGermany • Benedikt-beuernTel: (49) [email protected] HealthcareProductsTurkey • GaziantepTel: (90) [email protected] • PomeziaTel: (39) [email protected]

Metro InternationalUsa • Wilkes-Barre, PaTel: (1) [email protected] InternationalUsa • long Island City,nYTel: (1) 718-371-6026metropolismedical.comservice@metropolismedical.comMettler ElectronicsUsa • anaheim, CaTel: (1) 714-533-2221mettlerelectronics.commail@mettlerelectronics.comMiconveyTechnologiesChina • shanghaiTel: (86) [email protected] MedicalGreece • athensTel: (30) [email protected] EMEAUK • readingTel: (44) [email protected]’SFrance • lyonTel: (33) 4-72-78-00-40mils.fr [email protected] Medical InternationalChina • shenzhenTel: (86) [email protected] Usa • northbrook, IlTel: (1) [email protected] • MammendorfTel: (49) [email protected] - Medical International ResearchItaly • romeTel: (39) [email protected]

Mirion Technologies

Tel: (45) [email protected] republic • slanyTel: (420) [email protected] • WonjuTel: (82) 1577-8522listem.co.krLMT Medical SystemsGermany • lübeckTel: (49) 451-580-98-0lmtmedicalsystems.cominfo@lmtmedicalsystems.comLodenetherlands • GroningenTel: (31) [email protected] Systems south africa • JohannesburgTel: (27) [email protected] • GunpoTel: (82) [email protected] • YokneamTel: (972) 4-959-9000lumenis.comLutechUsa • ronkonkoma, nYTel: (1) [email protected] Tecnologia MédicaBrazil • são PauloTel: (55) [email protected] PharmaceuticalsUK • staines-Upon-ThamesTel: (44) 017-8463-6700mallinckrodt.comMaltron InternationalUK • rayleighTel: (44) [email protected] • Irvine, CaTel: (1) 949-297-7000

[email protected] • BarcelonaTel: (34) [email protected] • MunichTel: (49) [email protected] EndoscopyGermany • WurmlingenTel: (49) [email protected] • salt lake City, UTTel: (1) [email protected] ElectronicsChina • shenzhenTel: (86) 400-058-0755med-linket.commarketing@med-linket.comMed-XInternationalUsa • Bergenfield, nJTel: (1) [email protected]

Medcaptain Medical TechnologyChina • shenzhenTel: (86) [email protected] BeneluxBelgium • aalstTel: (32) [email protected] Healthcareswitzerland • BaarTel: (41) [email protected] • CharleroiTel: (32) [email protected]

MedGynUsa • addison, IlTel: (1) [email protected]

Medi-Safe Surgicalssouth africa • CapeTownTel: (27) 21-852-5715medi-safe.netinfo@medi-safe.netMedi-TechInternationalUsa • Brooklyn, nYTel: (1) 718-272-6390medi-techintl.commtiorderdesk@medi-techintl.comMediaidUsa • Cerritos, CaTel: (1) [email protected]

MedianaKorea • WonjuTel: (82) [email protected]

Medica Usa • Bedford, MaTel: (1) 781-275-4892medicacorp.comsales@medicacorp.comMedicalIlluminationInternationalUsa • san Fernando, CaTel: (1) [email protected] • TuttlingenTel: (49) [email protected] ElektronikaHungary • BudapestTel: (36) [email protected] • omerTel: (972) [email protected] • TaoyuanTel: (886-3) [email protected] Poland • WarsawTel: (48) [email protected] • Miami, FlTel: (1) 305-406-3931




Medec Benelux medecbenelux.beMedela Healthcare medela.comMedestime medestime.comMedi-Tech International meditechintl.comMediaid mediaidinc.comMediana mediana.co.krMedical Illumination International medillum.comMedical International research spirometry.comMedicor elektronika medicor.huMedima medima.com.plMedimar medimarcorp.comMedion Healthcare medion.co.inMediplus mediplus.co.ukMediracer mediracer.comMedisoft medisoft.beMedlab medlab.euMedset Medizintechnik medset.comMedtronic medtronic.comMeKICs mek.co.krMennen Medical mennenmedical.comMercury Medical mercurymed.comMerlin Medical merlin-medical.co.ukMesa laboratories mesalabs.comMesa Medizintechnik mesamed.deMetro International metro.comMIl’s mils.frMindray Medical International mindray.comMIPM mipm.comMirion Technologies mirion.comMIr Medical International research spirometry.comMyco Medical mycomedical.comnatus Medical natus.comnds surgical Imaging ndssi.comnidek Medical nidekmedical.comnihon Kohden nihonkohden.comnipro Medical nipro-group.comnitrocare nitrocare.com.trnonin Medical nonin.comnoraV Medical norav.comnouvag nouvag.comnova Biomedical novabiomedical.comnovair novairmedical.comnovos Medical systems novos.com.tro-Two Medical Technologies otwo.comokuman Medikal okuman.com.trolidef olidef.com.bromron Healthcare europe omron.euor Technology or-technology.comoricare oricaremed.comosatu bexencardio.comoutpatient supply outpatientsupply.com owen Mumford owenmumford.comPajunk pajunk.comPalco laboratories palcolabs.comParaid Medical systems paraid.co.ukPCI Precision Charts pcicharts.comPekato enterprises pekato.comPenlon penlon.comPerry Health perry-health.comPerlong Medical perlong-china.comPhilips Healthcare philips.com/medicalPhoenix Medical systems phoenixmedicalsystems.comPlasti-Med plasti-med.comPrecision Medical precisionmedical.comPrimedic primedic.comProaCT Medical proactmedical.co.ukProgetti Medical progettimedical.comProjesan Hospital Furniture projesan.com.trQuirumed quirumed.comraumedic raumedic.comreanimed reanimed.comrein Medical reinmedical.comresMed resmed.com

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Usa • Florham Park, nJTel: (1) [email protected] • Farmingdale, nYTel: (1) 631-694-9555misonix.comMitsubishi ElectricVisual and ImagingSystems Usa • Irvine, CaTel: (1) 949-465-6000me-vis.comMöller-WedelGermany • WedelTel: (49) 4103-9377-610moeller-wedeloptical.cominfo@moeller-wedel-optical.comMyco MedicalUsa • apex, nCTel: (1) [email protected] MedicalUsa • Pleasanton, CaTel: (1) 608-829-8500natus.comNDS Surgical ImagingUsa •san Jose, CaTel: (1) [email protected] •roosendaalTel: (31) [email protected]@neorad.noNessler Medizintechnikaustria • InnsbruckTel: (43) [email protected] • Farmingdale, nYTel: (1) [email protected] • danvers, MaTel: (1) [email protected] Medical SystemsChina • shenyangTel: (86) 24-8366-7788neusoftmedical.cominquiries@neusoft.comNewmedicalTechnology

Usa • northbrook, IlTel: (1) [email protected] MedicalUsa • Birmingham, alTel: (1) [email protected] KohdenJapan • TokyoTel: (81) 3-5996-8036nihonkohden.comNilymedIsrael • Tel-avivTel: (972) [email protected] EuropeBelgium • MechelenTel: (32) [email protected] • naganoTel: (81) 26-243-3895nisco-jp.jp

NitrocareTurkey • sivasTel: (90) [email protected]

Nonin MedicalUsa • Plymouth, MnTel: (1) [email protected] MedicalGermany • WiesbadenTel: (49) 6134 [email protected] • BergenTel: (47) [email protected] • ottawa, onTel: (1) [email protected] • GoldachTel: (41) [email protected] BiomedicalUsa • Waltham, MaTel: (1) [email protected]

France • roissy-en-FranceTel: (33) [email protected] • Colmar, PaTel: (1) [email protected] • american Fork, UTTel: (1) [email protected] Medical SystemsTurkey • ankaraTel: (90) [email protected]

NUVOUsa • erie, PaTel: (1) [email protected] MedicalTechnologiesCanada • Brampton, onTel: (1) [email protected] Medikal Turkey • ankaraTel: (90) [email protected] • ribeirao PretoTel: (55) [email protected] • HamburgTel: (49) 40-23773-0olympus-europa.com/[email protected] Healthcare Europenetherlands • HoofddorpTel: (31) [email protected] EndoscopySystemsGermany • sulzbachTel: (49) [email protected] • Colmenar ViejoTel: (34) [email protected]

OR Technology Germany • rostockTel: (49) [email protected] • BarcelonaTel: (34) [email protected] • Quakertown, PaTel: (1) [email protected] • ermuaTel: (34) [email protected] • signal Hill, CaTel: (1) [email protected] SupplyUsa • largo, FlTel: (1) [email protected] MumfordUK • oxfordshireTel: (44) [email protected] • scottsdale, aZTel: (1) [email protected] • GeisingenTel: (49) [email protected] Medical SystemsUK • BirminghamTel: (44) [email protected]

Parker LaboratoriesUsa • Fairfield, nJTel: (1) [email protected]

PaxeramedUsa • newton, Ma

Tel: (1) [email protected]

PCI Precision ChartsUsa • Bohemia, nYTel: (1) [email protected] EnterprisesUsa • Miami, FlTel: (1) [email protected] • abingdon, oxfordshireTel: (44) [email protected] • HamburgTel: (49) [email protected]

Perry HealthUsa • Miami, Fl Tel: (1) [email protected]

Perlong MedicalChina • nanjingTel: (86) [email protected] Healthcarenetherlands • BestTel: (31) [email protected] Medical SystemsIndia • ChennaiTel: (91) 93-8057-1151phoenixmedicalsystems.comexports@pmsind.comPlanmedFinland • HelsinkiTel: (358) [email protected] • IstanbulTel: (90) [email protected]

Korea • Goyang-CityTel: (82) [email protected] • TrevouxTel: (33) [email protected] MedicalUsa • northampton, PaTel: (1) 610-262-6090precisionmedical.cominfo@precisionmedical.comPrestige MedicalUK • BlackburnTel: (44) 1254-682-622prestigemedical.co.uksales@prestigemedical.co.ukPrimedic Germany • rottweilTel: (49) [email protected] MediaUsa • Miami, FlTel: (1) [email protected] MedicalUK • CorbyTel: (44) [email protected] Medical Italy • TurinTel: (39) [email protected] HospitalFurnitureTurkey • KayseriTel: (90) [email protected] • ernéeTel: (33) [email protected] ManufacturingUsa • Queens, nYTel: (1) [email protected]

PTW-FreiburgGermany • Freiburg


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Critical Care


SH MedicalUsa • Miami, FlTel: (1) [email protected] AnesthesiaUsa • Caledonia, MITel: (1) [email protected] ScalesIsrael • Beit KeshetTel: (972) [email protected] Wei USAUsa • Union City, CaTel: (1) [email protected]

Shimadzu MedicalSystemsJapan • KyotoTel: (81) 75-823-1111shimadzu.com

Shina SystemsIsrael • CaesareaTel: (972) [email protected] For MKorea • namyangjuTel: (82) [email protected] • CrespellanoTel: (39) [email protected]

Sibel Groupspain • BarcelonaTel: (34) [email protected] HealthcareGermany • erlangenTel: (49) 69-6682-6602siemens.com/healthcareSino-Hero Bio-MedicalElectronicsChina • shenzhenTel: (86) [email protected] • shantouTel: (86) [email protected]

SismatecBrazil • CuritibaTel: (55) [email protected] • londonTel: (44) [email protected] • elgin, IlTel: (1) [email protected] & NephewUK • WatfordTel: (44) 1923-477-100smith-nephew.comSmiths MedicalUsa • Minneapolis, MnTel: (44) [email protected] EnterprisesUsa • Miami, FlTel: (1) [email protected] MedicalTechnologyUsa • san Francisco, CaTel: (1) 415-666-3980solarismedtech.comsales@solarismedtech.comSoluscopeFrance • aubagneTel: (33) [email protected] TechnologyUsa • Bloomfield, CTTel: (1) [email protected] China • shenzhenTel: (86) [email protected] • Bothell, WaTel: (1) [email protected] • Weybridge, surreyTel: (44) 0-1256-483-481pro.sony.eu/[email protected]

Soyee ProductsKorea • seoulTel: (82) [email protected] HealthcareUsa • snoqualmie, WaTel: (1) 425-396-3300spacelabshealthcare.comSpectrum HealthcareUK • northamptonTel: (44) 01793-762928spectrumhealthcare.co.ukinfo@spectrumhealthcare.co.ukSpencerItaly • CollecchioTel: (39) [email protected] • riese PioTel: (39) [email protected]

StephanGermany • GackenbachTel: (49) [email protected] • la ricamarieTel: (33) [email protected] • Mentor, oHTel: (1) 440-354-2600steris.comSteris LatAmBrazil • são PauloTel: (55) 11-3372-9499sterislatam.com

SterylabItaly • MilanTel: (39) [email protected] • TorshällaTel: (46) [email protected], KarlGermany • TuttlingenTel: (49) [email protected] Medicalswitzerland •TaegerwilenTel: (41) [email protected]

Tel: (49) [email protected] InternationalUsa • Irvine, Ca Tel: (1) [email protected] • ValenciaTel: (34) [email protected]

RadcalUsa • Monrovia, CaTel: (1) [email protected]

RamSoftCanada • Toronto, on Tel: (1) 416-674-1347ramsoft.com RaumedicGermany • HelmbrechtsTel: (49) [email protected] • GebzeTel: (90) [email protected] MedicalGermany •MoenchengladbachTel: (46) [email protected] • BucheonTel: (82) [email protected] Careof AmericaUsa • st. Petersburg, FlTel: (1) 727-573-1595rcai.comResMedUsa • san diego, CaTel: (1) 858-836-5000resmed.comResponse BiomedicalCanada • Vancouver, BCTel: (1) [email protected] Medical Devicesspain • Madrid

Tel: (34) [email protected] ElectronicsUsa • la Fox, IlTel: (1) [email protected] Science &TechnologyChina • BeijingTel: (86) 10-6494-8021ureabreathtests.comchina-richen.com.cnRiester, RudolfGermany • JungingenTel: (49) [email protected] MedicalUK • Peterlee, Co.durhamTel: (44) [email protected] • espelkampTel: (49) [email protected] • BeijingTel: (86) [email protected] • solon, oHTel: (1) [email protected] Electronicssweden • MolndalTel: (46) [email protected] MedizintechnikGermany • FridingenTel: (49) [email protected] • Mineola, nYTel: (1) [email protected] Medical switzerland • ZurichTel: (41) [email protected] • seongnamTel: (82) 2-2194-1000samsungmedison.com

SamtronicBrazil • são PauloTel: (55) [email protected] IndustriesIsrael • ashdodTel: (972) 8-862-8308savion.co.ilSchaerer Medicalswitzerland • MunsingenTel: (41) 31-720-2200schaerermedical.chinfo@schaerermedical.chSchillerswitzerland • BaarTel: (41) [email protected] u. SöhneGermany • WickedeTel: (49) 23-77-84-0schmitz-soehne.comzentrale@schmitz-soehne.deSchwa-MedicoGermany • ehringshausenTel: (49) [email protected] • HamburgTel: (49) [email protected] IndustriesUsa • anaheim, CaTel: (1) [email protected] • linkopingTel: (46) [email protected] • algeteTel: (34) [email protected] Medical UK • suffolkTel: (44) [email protected] HealthcareKorea • seoulTel: (82) [email protected]

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Surgical Techniques



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148 ampronix . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .48– aoCr 2021 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12111 BioFire . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11117 CIrs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17– CIrse 2020 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .15108 Clear Image devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8– eFsUMB . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .44– eUronero 2021 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .45– expomed eurasia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18121 Feather . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21113 Greiner Bio-one . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13– HospiMedica.com . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4106 Innolcon Medical Technology . . . . . . . . . . . . . . . . . . . . . . . .6– International surgical Week . . . . . . . . . . . . . . . . . . . . . . . . .17102 Mayo Clinic laboratories . . . . . . . . . . . . . . . . . . . . . . . . . . . .2103 Medical Fair asia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18105 Parker . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5103 Perry Health . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3122 radcal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23109 sun nuclear . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9– TradeMed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7139 Vicolab . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .39

Vol. 38 no.36-7/2020

HospiMedica International


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