Dr Vijay Marakala

Biochemistry

SIMS & RC

8/16/2013 2:47 AM

Metabolism

Sum of all the chemical transformations taking place in a cell or organism,

occurs through a series of enzyme-catalyzed reactions that constitute

metabolic pathways.8/16/2013

2:47 AM

8/16/2013 2:47 AM

Precursor Intermediates Product

Metabolite

s 8/16/2013

2:47 AM

Intermediary metabolism

Combined activities of all the metabolic pathways that interconvert precursors, metabolites, and products

8/16/2013 2:47 AM

CatabolismAnabolism

8/16/2013 2:47 AM

CatabolismAnabolism

8/16/2013 2:47 AM

8/16/2013 2:47 AM

8/16/2013 2:47 AM

Methods of study of Intermediary metabolism

Use of whole organisms or its components

Use of metabolic probes

Use of isotopes

8/16/2013 2:47 AM

Use of whole organism or its components

Whole organism

Isolated organs

Organ slices

Intact cells8/16/2013

2:47 AM

Methods of study of Intermediary metabolism

Use of whole organisms or its components

Use of metabolic probes

Use of isotopes

8/16/2013 2:47 AM

Utility of metabolic probes

Inhibitors Mutants

8/16/2013 2:47 AM