INTEGUMENTARY SYSTEM Slide #10 (926). Skin, monkey

stratum basale

melanocytes

stratum spinosum

keratohyalin granules

stratum granulosum

stratum corneum

Keratin inside denucleated cell shells

stratum lucidum

dermis dermis

Slide #10 (926). Skin, monkey

melanocytes

. The epidermal projections are known as epidermal ridges (rete pegs), while the alternating dermal extensions are termed dermal papillae.

stratum corneum

stratum granulosum

stratum spinosum

stratum basale

Slide #10 (926). Skin, monkey

The elaborate interdigitation of these two layers occurs because INTERDIGITATION INCREASES THE TOTAL AMOUNT OF SURFACE AREA TO FACILITATE ATTACHMENT OF THE EPIDERMIS TO THE DERMIS AND TO INCREASE SURFACE AREA FOR DIFFUSION OF NUTRIENTS AND GASES TO THE EPIDERMIS FROM THE DERMIS

rete pegs dermal papillae.

Epidermal – dermal interface creates unique finger prints

Rete pegs

Finger print

stratum lucidum

dermal papillae.

finger pad

Slide #10 (926). Skin, monkey

Pacinian corpuscle PRESSURE RECEPTOR

20x

Meissner’s corpuscle Light touch receptor

sweat glands

rete peg

rete peg

Skeletal muscle

dermis

Slide #10 (926). Skin, monkey Sweat glands

Myoepithelial cell

Sweat duct

White fat

CCT

DEMO SLIDE BOX 240 - Skin from a digital pad, dog. stratum granulosum stratum lucidum stratum corneum

compound hair follicles

Myoepithelial cells

Slide #19 (449-E001-H-132). Skin, horse

hair follicles

arrector pili muscles

sebaceous glands

sweat glands

Slide #19 (449-E001-H-132). Skin, horse Melanocytes (clear cells on basal layer

nuclei of myoepithelial cells

sweat glands

Slide #19 (449-E001-H-132). Skin, horse Skeletal muscle

nerve

muscular artery

Sebaceous glands

arrector pili muscle Smooth muscle

DEMO SLIDE BOX 215. Demo slide #215a. Skin of metacarpal pad, cat. Pacinian corpuscle

UNILOCULAR ADIPOSE TISSUE (WHITE FAT)

SMOOTH MUSCLE

COLLAGENOUS CONNECTIVE TISSUE (CCT)

ENDOTHELIUM (SIMPLE SQUAMOUS EPITHELIUM) [in a BLOOD vessel]

NERVE

Slide #20 (R-H-82). Skin, rat. sinus (tactile) hair follicles

SINUS HAIRS ARE MOST NUMEROUS ON THE HEAD / FACE REGION ; THE FUNCTION OF SINUS HAIRS IS “TOUCH” RECEPTION OR ORIENTATION OF THE HEAD / FACE (OR TO A LESSER EXTENT YOU COULD SAY THE BODY) IN THE ENVIRONMENT

Slide #20 (R-H-82). Skin, rat. Skeletal muscle

Mast cells

Slide #95 (Rbt 85B). skin and sinus hairs, rabbit.

sinus (tactile) hair follicle

Demo Slide 227 (C-H-4). Anal sac, dog anocutaneous junction

WHITE FAT

cross section of one sac and is lined by keratinized stratified squamous epithelium

apocrine sweat glands, the glands of the anal sac

SKELETAL MUSCLE

Anal sac

Demo Slide 227 (C-H-4). Anal sac, dog

WHITE FAT

SKELETAL MUSCLE

nerve

CCT

ENDOTHELIUM

apocrine sweat glands

White fat

Slide #43 (K9-1). Anal region, dog.

rectoanal junction

non-keratinized epithelium,

the goblet cells among disrupted simple columnar epithelium

Slide #43 (K9-1). Anal region, dog. rectoanal junction and regional skin

non-keratinized epithelium,

Apocrine sweat glands keratinized

epithelium,

Circumanal gland

gut

gut

Slide #43 (K9-1). Anal region, dog.

non-keratinized epithelium,

circumanal glands are considered modified sebaceous glands

keratinized epithelium,

DEMO SLIDE BOX 62 – Anal region, dog.

NONKERATINIZED STRATIFIED SQUAMOUS [EPITHELIUM

KERATINIZED STRATIFIED SQUAMOUS [EPITHELIUM]

SIMPLE COLUMNAR [EPITHELIUM] [= RECTUM ; NOTE GOBLET CELLS ARE PRESENT]

circumanal glands

SMOOTH MUSCLE [= INTERNAL ANAL SPHINCTER] SKELETAL MUSCLE [= EXTERNAL ANAL SPHINCTER]

DEMO SLIDE BOX 62 – Anal region, dog.

Sheep lip slide 83

tactile hair follicle

Slide #83 (SP-1-79). Skin of lip, sheep.

skin

oral cavity

skin adnexa (i.e. hair/hair follicles, sebaceous & sweat glands, arrector pili muscles

NONKERATINIZED STRATIFIED SQUAMOUS [EPITHELIUM] KERATINIZED STRATIFIED SQUAMOUS [EPITHELIUM]

Slide #83 (SP-1-79). Skin of lip, sheep. Mixed glands

SKELETAL MUSCLE

UNILOCULAR ADIPOSE TISSUE (WHITE FAT)

COLLAGENOUS CONNECTIVE TISSUE (CCT)

DEMO SLIDE BOX 27 – Hoof, donkey.

keratinized stratified squamous epithelium

adnexa

rete pegs (epidermal ridges) and dermal papilla

perioplic region with predominant rete pegs dermal papilla

Epidermal – dermal interface

dermis

dermis

rete pegs

dermal papilla dermis dermis

Finger skin finger skin equine hoof

Tubular horn

DEMO SLIDE BOX 27 – Hoof, donkey.

stratum corneum that was produced in the perioplic region is called the STRATUM EXTERNUM

STRATUM EXTERNUM

horn tubules non-tubular or intertubular horn

coronary region = the junction of the epidermis with the dermis.

coronary region

perioplic region

epidermis

dermis

Primary & secondary epidermal laminae

DEMO SLIDE BOX 27 – Hoof, donkey. coronary region

stratum basale (note the melanocytes and melanin pigment) and stratum spinosum

dermis

DEMO BOXES 28, 29. Equine hoof (H&E – BOX 28 & trichrome – BOX 29

Primary & secondary epidermal laminae

horn tubules non-tubular or intertubular horn

DEMO BOXES 28, 29. Equine hoof (H&E – BOX 28 & trichrome – BOX 29

CCT of the corium will stain blue and the epidermal structures will stain red

Primary & secondary epidermal laminae

horn tubules non-tubular or intertubular horn

Equine hoof (H&E – BOX 28) is unique with its secondary epidermal laminae

SECONDARY LAMINAE ALLOW OR PROVIDE INCREASED SURFACE AREA FOR ATTACHMENT OF THE HOOF WALL TO BONE TO HELP SUSPEND THE WEIGHT OF THE HORSE BETWEEN THE HOOF WALL AND THE DISTAL PHALANX

Slide #157 (GT1-63). Hoof, fetal goat ruminants do NOT possess secondary laminae (either epidermal or dermal).

primary epidermal laminae

All cloven hoofed animals (which includes pigs) will have hooves that both grossly and microscopically resemble the ruminant hoof.

Bone = SPONGY (TRABECULAR OR CANCELLOUS)

CORIUM

digital cushion

Slide #157 (GT1-63). Hoof, fetal goat

stratum externum is composed of horn tubules (tubular horn) and intertubular horn, just like the stratum medium

primary epidermal laminae stratum externum

stratum medium

stratum medium stratum externum

Epithelium CCT

DEMO SLIDE BOX 229. Fetal goat hoof.

Primary dermal and epidermal laminae

Hyaline cartilage that forms articular cartilage

nonarticular hyaline cartilage growth plate with the four zones of cartilage

Collagenous connective tissue (CCT),

CCT that is forming tendons

Hair follicles of Integument

adnexa

DEMO SLIDE BOX 159 (1089) –Developing bones and synovial joint, kitten.

primary center of ossification

Zone of reserve (resting) cartilage—this zone appears as an area of typical hyaline cartilage. Zone of proliferative chondrocytes—characterized by chondrocytes that are arranged in rows (like stacks of coins). Zone of mature (hypertrophied) chondrocytes—in this zone, both the chondrocytes and lacunae have enlarged at the expense of the matrix, reducing it (the matrix) to thin strands. Zone of calcified chondrocytes/cartilage matrix—

Zone of erosion and ossification

DEMO SLIDE BOX 229. Fetal goat hoof. Primary dermal and epidermal laminae

Hyaline cartilage

CCT that is forming tendons

Spongy or (trabecular/cancellous) bone and Periostium

DEMO SLIDE BOX 229. Fetal goat hoof.

Integument, including adnexa: Hair Hair follicles Sebaceous glands

Integument, including adnexa:

Arrector pili muscles

bone

hoof Hyaline cartilage

DEMO BOX 216 – Cat claw.

corium

epidermis (including the strata basale, spinosum, and corneum of the wall)

claw

DEMO BOX 216 – Cat claw.

epidermis (including the corneum of the wall, Spinosum, and strata basale)

Corium

DEMO BOX 216 – Cat claw

Region of the coronary border

Claw fold Central (dorsal) ridge

Claw plate

corium

sole

Tip of claw

http://www.ncbi.nlm.nih.gov/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Click%20on%20image%20to%20zoom&p=PMC3&id=2736126_joa0214-0620-f6.jpg