Innovation through Bioscience · Adooq Bioscience Kinase Inhibitors Catalog 2014-2015 Adooq...

Adooq Bioscience

Kinase Inhibitors Catalog 2014-2015

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Adooq Bioscience is one of the world leading suppliers of high-performance life-science reagents and reference compounds for the research fields. Now, Adooq has more than 4200 products with validated biological and pharmacological activities, and an unique collection of over 2000 inhibitors on HDAC, PI3K, Apoptosis and more signaling pathways in stock.

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III IVCathepsin 34Histone demethylases 34Stem Cell Differentiation 34

GSK-3 / Wnt / Hedgehog .............................. 35γ-Secretase 35Hedgehog 35Wnt 35β-catenin 36GSK-3 36Smoothened 36

Transporters ......................................................... 37ATPase 37Multidrug Transporters 37Sodium-dependent Glucose Cotransporter (SGLT) 37Monocarboxylate transporters (MCT) 37Neurotransmitter Transporters 38AMPA receptor 38

Ion Channels ........................................................ 38Calcium Channels 38P-gp 38CRM1 38Ligand-gated Ion Channels 38Sodium Channels 39Potassium Channels 39Chloride Channels 39Cystic Fibrosis Transmembrane Regulator (CFTR) 39Transient Receptor Potential Channels 40

AMPK / Insulin Receptor ............................... 40AMPK 40

ATM / ATR ........................................................ 40ATM 40NMDA Receptors 40ATR 40

7-TM Receptors ................................................. 415-HT Receptors 41Adrenergic Receptors 41Acetylcholine Muscarinic Receptors 42Histamine Receptors 42Dopamine Receptors 42Opioid Receptors 42GABA Receptors 42Purinergic (P2Y) Receptors 42Metabotropic glutamate receptors (mGluR) 43Angiotensin Receptors 43Melatonin Receptors 43Peptide Receptors 43Smoothened Receptors 43Chemokine Receptors (CCR5) 43G Protein 43Platelet-Activating Factor (PAF) Receptors 43Endothelin Receptors 43P2X Receptor 43LPA Receptor 43Prostanoid Receptors 43Adenosine Receptors 44Cannabinoid Receptors 44Neurotensin Receptors 44

Endocrinology / Hormones ............................ 44Pregnane X Receptors 44Estrogen Receptors 44Leukotriene receptor 44Orexin Receptors 44Somatostatin Receptors 44NK1 Receptors 44Protease-Activated Receptors (PAR) 44

Progesterone Receptors 44Renin-angiotensin-aldosterone system (RAAS) 45Androgen Receptors 45PPAR 45Liver X receptors (LXRs) 45Aromatase 46Retinoic Acid Receptors 46Glucocorticoid receptors 46

Transferases .......................................................... 46Glucocorticoid receptors 46Vitamin D Receptors 46GnRH receptor 46GPR 46Phosphorylases 46Methyltransferases 47Protein Prenyltransferases 47FPTase 47Histone Methyltransferase 47Histone Acetyltransferases 47DNA Methyltransferases 47

Ubiquitin .............................................................. 48activating enzyme E1 48E3 ubiquitin ligase 48DUB 48

Others .................................................................... 48Other inhibitors 48p97 48Carbonic Anhydrase 54Cholinesterase 54Casein Kinase 2 54Soluble guanylyl cyclase (sGC) 54Reagents 54Integrin Receptors 54Toll-like Receptors 54Beta-secretase (BACE) 54LRRK2 54MELK 54β-lactamase 55Gluconeogenesis 55Cholinesterases 55Aldose Reductase 55Nitric Oxide Signaling 55Adenylyl Cyclase 55IDH1 55LSD1 inhibitor 55Casein Kinase 1 55Lipoxygenase 55Sigma-1 receptor 55

Contents Contents

ContentsApoptosis .................................................................1

Bcl-2 Family 1Caspase 1p53 1TNF-α� 1IAP 1RasGAP (Ras- P21) 2PERK 2

Angiogenesis ............................................................2EGFR / HER2 2MDM2 2Apoptosis Inducers 2FGFR 3PDGFR 3VEGFR 3Vascular Disrupting Agent (VDA) 4HIF 5

MAPK ......................................................................5MEK/ERK 55-alpha-reductase 5Antiangiogenics 5p38-MAPK 6JNK/c-Jun 6Raf 6

Cell Cycle .................................................................7Checkpoint Kinase 7cyclin-dependent kinases (CDKs) 8Checkpoint Control Kinases 9Aurora Kinase 9PARP 9Polo-like kinases (PLKs) 10Rho-Kinase (ROCKs) 10Topoisomerase 11Microtubules 11Synthases / Synthetases 12RNA/DNA Polymerase 12Telomerase 12Ligases 12Reverse Transcriptase 12

Cell Metabolism .................................................. 13Cytochrome P450 13Mitosis 13β-Amyloid 14Phosphodiesterases (PDEs) 14Hydroxylases 14Dihydrofolate reductase (DHFR) 15Dehydrogenases 15Cyclooxygenase (COX) 15Antimetabolite 16Histone Deacetylase (HDAC) 16Sir2-like Family Deacetylases (sirtuins) 17Monoamine Oxidase (MAO) 17Factor Xa 17Kinesin Spindle Protein 18DNA, RNA and Protein Synthesis 18CYP17 18Phospholipases 19Lipid Metabolism 19FAAH 19CETP 19DNA Methyltransferases 19HMG-CoA Reductase 19Neuronal Metabolism 19IDO 19

PI3K / Akt / mTOR........................................ 20Akt 20Ferroptosis 20PI3-Kinase (PI3K) 20mTOR 22PDK1 23

Receptor Tyrosine Kinases ................................. 23EGFR/HER2 23DNA-dependent protein kinase (DNA-PK) 23Ribosomal S6 protein kinases (RSK) 23FGFR 24PDGFR 24VEGFR 24Type 1 insulin-like growth factor receptor (IGF-1R) 24FLT3 (FMS-like tyrosine kinase 3) 25c-MET 25ALK 25BCR-ABL 26FAK 26SRC 26c-Kit 27Spleen tyrosine kinase (Syk) 27Tie-2 27Bone Morphogenetic Proteins (BMP) 28Bruton's tyrosine kinase 28

NF-kB/IkB .......................................................... 28NF-kB 28Axl 28Tyrosine kinase 28Trk Receptors 28Cytokines 29IKK 29

JAK / Stat ............................................................ 29JAK 29Stat 29Pim Kinase 29

TGF-β / Smad ................................................... 30TGF-β�/ Smad Inhibitors 30Protein Kinase C (PKC) 30

Proteases ................................................................ 30Caspase 30Protein Kinase A 30Protein kinase D (PKD) 30Proteasome 30HCV Protease 31HIV Protease 32Heat Shock Proteins (HSP) 32Aminopeptidase 33Integrase 33Dipeptidyl Peptidase IV (DPP-4) 33Thrombin 33Angiotensin-Converting Enzyme (ACE) 33Matrix Metalloprotease 33Other Proteases 33MMP 34

Epigenetics ............................................................ 34Bromodomain 34

Stem Cells ............................................................. 34Stem Cell Proliferation 34


1 2

ApoptosisBcl-2 FamilyA10022 ABT-263 (Navitoclax)

A10255 ABT-737

A10665 Obatoclax mesylate (GX15-070)

A10955 TW-37

A11448 HA14-1

A12500 ABT-199

A12743 BM-1074

A12823 Sabutoclax

A12907 BAM 7

A13578 AT101

ABT-737 is a pan-Bcl-2 inhibitor. IC50 values ranged from 192 nM (the pre-B cell line Hal-01) to <10 μM (Nalm-6, K562 and HL-60).*Available package size: 5,10,50,100mg

CaspaseA10984 VX-765

A11090 PAC-1

A11944 Apoptosis Activator 2

A12373 Z-VAD-FMK

A13070 LY573636 (Tasisulam)

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID.*Available package size: 10,25,50,100mg

VX-765 is a novel Caspase-1 inhibitor,which is an enzyme that controls the generation of two cytokines, IL-1b and IL-18.*Available package size: 5,10,50,100mg

p53

A10491 JNJ 26854165

A11931 RITA (NSC 652287)

A11943 Tenovin-1

A12305 Tenovin-6

A12449 Pifithrin-u

A12450 Pifithrin-beta

A12451 Pifithrin-alpha

A12930 NSC 319726

A13581 PRIMA-1

A13727 Tenovin-3

JNJ-26854165 is one of p53-activating agents and synergizes with AraC or doxorubicin to induce p53-mediated apoptosis and may provide a novel therapeutic approach for the treatment of acute leukemias.*Available package size: 5,10,50,100mg

TNF-αA10522 Lenalidomide (CC-5013)

A10743 Pomalidomide (CC-4047)

A11957 Bay 11-7821

A11973 Necrostatin-1

A12748 QNZ

IAPA11002 YM155

A11163 AT-406

A11928 LCL-161

A12738 Birinapant (TL32711)

YM155 is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.*Available package size: 5,10,25,100mg

RasGAP (Ras- P21)

A10935 Tipifarnib (Zarnestra)

A11225 Pluripotin (SC-1)

A11930 PF-3758309

PF-3758309 is a small-molecule p21-activated kinase inhibitor inhibiting oncogenic signaling and tumor growth.*Available package size: 5,10,25,50mg

MDM2

A10657 Nutlin-3

A11179 NSC-207895 (XI-006)

A11501 Nutlin 3a

A11502 Nutlin 3b

A13582 MDM2 Inhibitor

MDM2 antagonist Nutlin-3 is a potent inducer of apoptosis.*Available package size: 5,25,50,100mg

Apoptosis Inducers

A10582 Methylprednisolone

A11279 FK866

A11635 Cyclophosphamide monohydrate

A11988 Gambogic acid

PERKA12792 GSK2606414

A13577 GSK2656157

A13816 ISRIB (trans-isomer)

Apoptosis Apoptosis

A13750 Hypothemycin

AngiogenesisEGFR / HER2A10043 AEE788

A10047 AG-490

A10053 Tyrphostin AG 879

A10062 AST-6

A10116 AZD8931

A10141 BIBW2992 (Afatinib)

A10210 Chrysophanic acid (Chrysophanol)

A10211 Canertinib (CI-1033)

A10242 CP-724714

AG-490 is a selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and ErbB2 respectively).*Available package size: 10,50,100,200mg

BIBW2992 (Afatinib) is tyrosine kinase inhibitor (TKI) that irreversibly inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.*Available package size: 5,10,25,100mg

A10362 Erlotinib Hydrochloride

A10422 Gefitinib (Iressa)

A10514 Lapatinib Ditosylate

A10612 Mubritinib (TAK 165)

A10638 Neratinib (HKI-272)

A10678 OSI-420

A10702 PD153035 (HCl salt)

A10706 Pelitinib (EKB-569)


3 4

A11028 AV-412

A11051 PF299804

A11057 XL647

A11155 AST-1306

A11158 ARRY334543

A11209 BMS 599626 (AC480)

A11236 TAK-285

A11263 BMS-690514

A11334 BIBX 1382

ARRY-380 is an ErbB-2 inhibitor that selectively binds to and inhibits the phosphorylation of ErbB-2, resulting in growth inhibition and death of ErbB-2-expressing tumor cells.*Available package size: 5,10,50,100mg

TAK-285 is an investigational HER2/EGFR inhibitor that penetrates the CNS in Rats with an Intact Blood Brain Barrier (BBB).*Available package size: 5,10,25,50mg

A11407 Apatinib (YN968D1)

A11558 SU-5402

A11752 Lapatinib (free base)

A11948 AP26113

A11949 AG-17

A12448 Butein

BIBX 1382 is a cell-permeable pyrimido-pyrimidine compound that acts as a potent, reversible, ATP-competitive, and highly selective inhibitor of EGFR.*Available package size: 5,10,25mg

PKC 412 is a broad spectrum protein kinase inhibitor. Inhibits conventional PKC isoforms (α, β, γ), PDFRβ, VEGFR2, Syk, PKCη, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Displays potent antitumor activity.*Available package size: 5,10,25mg

FGFRA10703 PD173074

A11075 AZD4547

A11159 BGJ398 (NVP-BGJ398)

A11244 LY 2874455

PDGFRA10504 KRN 633

A10880 Sunitinib Malate

A10903 Telatinib (BAY 57-9352)

A11052 Crenolanib (CP-868596)

A11350 CP-673451

A11581 Toceranib (PHA 291639, SU 11654)

A11753 MK-2461

A11978 Delphinidin chloride

Toceranib is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ.*Available package size: 5,10,25,50mg

VEGFR

A10025 Linifanib (ABT-869)

Linifanib (ABT-869) is a structurally novel, potent inhibitor of RTK, VEGF and PDGF with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGFR-β, KDR, and CSF-1R, respectively. *Available package size: 5,10,50,100mg

Angiogenesis Angiogenesis

A10049 Albendazole

A10101 Tivozanib (AV-951)

A10103 Axitinib

A10137 Bibf1120 (Vargatef)

BIBF1120 (Vargatef ) is a novel triple angiokinase inhibitor that inhibits three growth factor receptors simultaneously: VEGFR, PDGF and FGFR. *Available package size: 5,10,50,100mg

Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM.*Available package size: 5,10,50,200mg

A10162 Brivanib alaninate (BMS-582664)

A10185 Cediranib (AZD2171)

A10204 Chloroxine

A10248 CYC116

A10254 Brivanib (BMS-540215)

A10259 Imatinib (Gleevec)

A10340 E7080 (Lenvatinib)

E7080 is a multi-kinase inhibitor that inhibits both VEGFR2 and VEGFR3 kinases.*Available package size: 5,10,50,100mg

A10495 Kaempferol

A10502 Ki8751

A10608 Motesanib Diphosphate (AMG-706)

A10699 Pazopanib Hydrochloride (GW786034)

A10893 Taxifolin

A10953 TSU-68 (SU6668)

TSU-68 (SU-6668) is an inhibitor of RTKs involved in VEGF, bFGF and PDGF signaling, which inhibits endothelial cell proliferation.*Available package size: 5,10,50,100mg

A10963 Vandetanib (ZD6474)

A10967 Vatalanib (PTK787) 2HCl Base

A10996 XL184 free base (Cabozantinib)

A10990 WZ3146

A10991 WZ4002

A10992 WZ8040

A11022 AG-1478 (Tyrphostin AG-1478)

A11027 Arry-380

A12650 PKC 412

A12867 CGP-52411

A12868 ARRY-543


A13681 AZD-9291

A13718 Icotinib Hydrochloride

A13755 CNX-2006

A13825 Icotinib

XL184 free base (Cabozantinib) is a small molecule designed to inhibit multiple receptor tyrosine kinases, specifically MET and VEGFR2.*Available package size: 5,10,50,100mg

SU 5416 is an inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and RET.*Available package size: 10,25,50,100mg

TPT-260 is a thiophene thiourea derivative.*Available package size: 5,10,25,50mg

A11396 E-7050 (Golvatinib)

A11496 Motesanib (AMG706)

A11557 SU14813

A11772 CP-547632

A11954 ZM 323881 hydrochloride


A12027 (-)-Catechin gallate

A12437 SU 5416 (Semaxinib)

A13234 SKLB1002

A13377 SAR131675

A13465 SKLB610

A13966 TPT-260 (Dihydrochloride)

Vascular Disrupting Agent (VDA)

A10324 DMXAA (ASA404)


5 6

HIFA10012 2-Methoxyestradiol

A11237 FG-4592

A11924 IOX 2

A12883 FM19G11

A12921 HIF-C2

A12978 BAY 87-2243

FG-4592 is a novel hypoxia inducible factor prolyl hydroxylase inhibitor, in CKD anemia.*Available package size: 10,25,50,100mg

5-alpha-reductase

A10037 Aciclovir (Acyclovir)

A10188 Cefditoren pivoxil

A10338 Dutasteride (Avodart)

A10387 Finasteride

A10631 Nefiracetam (Translon)

AntiangiogenicsA12601 Combretastatin A4

Combretastatin A4 is an antitumor, anti-angiogenic and antimetastatic agent, in vitro and in vivo. Inhibits tubulin polymerization.*Available package size: 10,25,50,100mg

DMXAA (ASA404) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.*Available package size: 5,25,50,100mg

A10654 NPI-2358 (Plinabulin)

MAPK

Angiogenesis

MEK/ERK

A10089 AS703026

A10115 AZD8330

A10150 BIX02188

A10151 BIX 02189

BIX02188 is a potent and selective inhibitor of MEK5.*Available package size: 5,10,50,100mg

A10212 PD184352 (CI-1040)

A10256 PD0325901

PD0325901 is MEK inhibitor and non-competitive with ATP, Kiapp of 1 nM against activated MEK1 and MEK2.*Available package size: 5,10,25,100mg

A10257 AZD6244 (Selumetinib)

A10453 Honokiol

A10704 PD318088

A10705 PD98059

PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase.*Available package size: 10,50,100,200mg

A10957 U0126-EtOH

A11029 GSK1120212 (JTP-74057, Trametinib)

A11040 TAK-733

A11247 RO4927350

RO4927350 is a potent and highly selective non-ATP-competitive MEK1/2 inhibitor.*Available package size: 5,10,25,50mg

A11441 GDC-0973

A11493 MEK162 (ARRY-438162)

A11794 VRT752271

A12002 Arctigenin

A12505 TCS ERK 11e (VX-11e)

A12824 SCH772984

A12866 Refametinib (RDEA-119, BAY 86-9766)

A13135 Kobe0065

A13272 RO4987655

A13420 GDC0994

A14019 RO5126766

SCH772984 is a novel, specific inhibitor of ERK-1/2 with IC50 of 4 nM and 1 nM, respectively.*Available package size: 5,10,25,50mg

p38-MAPK

A10092 Asiatic acid

A10148 Doramapimod (BIRB-796)

JNK/c-Jun

A10860 SP600125

A11296 AS 602801 (Bentamapimod)

A11352 CC-401

A11969 TCS JNK 5a

RO5126766, also known as CH5126766, is a protein kinase inhibitor specific for the Raf and MEK mitogen-activated protein kinases (MAPKs) with potential anti-neoplastic activity.*Available package size: 5,10,25mg

A10545 LY2228820

A10823 SB 202190

A10824 SB 203580

Doramapimod (BIRB 796) is a small molecule inhibitor of p38 MAPK,which plays a critical role in regulating the production of proinflammatory cytokines.*Available package size: 5,10,50,100mg

SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.*Available package size: 25,50,100,200mg

A10976 Vinorelbine (Navelbine)

A10982 VX-702

A10983 VX-745

A11078 PH-797804

A11221 PD 169316

A11321 Skepinone-L

A11562 SB 239063

A11582 TAK-715

A12021 Asiaticoside

A12408 ML-3043

A12770 Talmapimod (SCIO-469)

Talmapimod (SCIO-469) is a selective, ATP-competitive p38 inhibitor (IC50 = 9 nM for p38α in vitro).*Available package size: 10,25,50,100mg

TCS JNK 5a is a highly selective inhibitor of JNK2 and JNK3 (pIC50 values are 6.7, 6.5, <5.0 and <4.8 for JNK3, JNK2, JNK1 and p38?? respectively).*Available package size: 10,25,50mg

A12749 JNK-IN-8

Raf

A10001 Sorafenib (Nexavar)

A10002 PLX-4720

A10420 GDC-0879

A10661 NVP-BHG712

A10739 PLX4032 (Vemurafenib)

MAPK


7 8

A10773 RAF265 (CHIR-265)

A10774 Raf265 derivative

A10829 SB590885

A11063 AZ628

A11077 ZM 336372

A11240 MLN2480 (BIIB-024)

A11333 BRAF inhibitor

A11381 Dabrafenib (GSK2118436A)

A11436 GW 5074

A12578 Kobe2602

A12739 PF-04880594

A12891 Diazepinomicin

A13226 LGX 818

LGX818 is an orally available Raf kinase inhibitor with potential antineoplastic activity.*Available package size: 1,5,10,25mg

Dabrafenib is a potent and selective inhibitor of B-RAF protein kinase carrying V600E mutation, currently in clinical trial.*Available package size: 5,25,50,100mg

RAF265 (CHIR-265) is an oral, highly selective RAF and VEGFR kinase inhibitor, which is to control or normalize VEGFR-2 along with the inhibition of B-raf and c-Raf mutation to prevent cancers.*Available package size: 5,10,25,50mg

PLX4032 (Vemurafenib) also known as RG7204, Vemurafenib, R7204; RO5185426. PLX4032 is a B-raf inhibitor with an IC50 of 44 nM.*Available package size: 10,50,100,200mg

A13323 TAK-632

A13525 L-779450

Cell CycleCheckpoint KinaseA10113 AZD7762

A10599 MK-1775

cyclin-dependent kinases (CDKs)

MK-1775 is a potent and selective Wee1 kinase inhibitor in vitro and in vivo.*Available package size: 5,10,25,50mg

A11036 LY2603618 (IC-83)

A11046 CHIR-124

CHIR-124 is a novel and potent Chk1 inhibitor (IC50: 0.32 nM and 697 nM for Chk1 and Chk2 respectively).*Available package size: 5,10,25,100mg

A11108 CCT241533

A11167 SCH 900776 (MK-8776)

A11520 PF 477736

A12703 SCH900776

SCH900776 is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.*Available package size: 5,10,25,50mg

A13403 ZCL-278

A13575 BML-277

A10093 AT7519

AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation.*Available package size: 5,25,50,100mg

A10163 BS-181 HCl

A10390 Flavopiridol (Alvocidib)

Flavopiridol (Alvocidib) is a cyclin-dependent kinase inhibitor under clinical development for the treatment of chronic lymphocytic leukemia.*Available package size: 5,10,25,50mg

MAPK Cell Cycle

PD 0332991 HCl is an orally available pyrido-pyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.*Available package size: 5,10,25,50mg

SNS-032 (BMS-387032) is a highly selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9, with in vitro growth inhibitory effects and ability to induce apoptosis in malignant B cells.*Available package size: 5,10,50,100mg

Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC₅₀ = 400 nM), CDK2/cyclin A (IC₅₀ = 680nM) , CDK5 (IC₅₀ = 850nM) and with much less effect other kinases.*Available package size: 10,50,100mg

P276-00, a novel cyclin-dependent inhibitor induces G1-G2 arrest, shows antitumor activity on cisplatin-resistant cells and significant in vivo efficacy in tumor models.*Available package size: 5,10,25mg

BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity.*Available package size: 5,10,25,50mg

A10494 JNJ-7706621

A10701 PD 0332991 HCl

A10716 PHA-793887

A10806 Roscovitine (Seliciclib)

A10850 SNS-032 (BMS-387032)

A11045 Flavopiridol HCl

A11047 PHA-848125 (Milciclib)

A11105 AZD5438

A11129 Dinaciclib (SCH 727965)

A11154 BMS-265246

A11164 PHA-767491

A11190 R547

A11220 Kenpaullone

A11313 AT7519 HCl

A11347 CGP60474

A12352 Purvalanol B

A12438 NU 6102

A12742 BAY 1000394

A12989 LY2835219

A13454 SB1317 (TG-02)

A13547 P276-00

A13549 LEE011

A13677 BMS-863233 (XL-413)

A13721 TG003


9 10

Checkpoint Control Kinases

A11036 LY2603618 (IC-83)

A11108 CCT241533

Aurora KinaseA10004 MLN8237 (Alisertib)

A10095 AT9283

A10100 Aurora A Inhibitor I

A10109 AZD1152-HQPA (Barasertib)

A10184 CCT129202

A10248 CYC116

A10448 Hesperadin

A10601 MLN8054

A10714 PHA-680632

A10715 Danusertib (PHA-739358)

A10851 SNS-314

A10981 VX-680 (MK-0457, Tozasertib)

A11009 ZM-447439

A11066 AMG 900

A11067 TAK-901

A11081 CCT137690

A11168 GSK1070916

A11171 PF-03814735

A11410 MK-5108 (VX-689)

MLN8237 (Alisertib) is a selective Aurora kinase A inhibitor with a median IC50 of 61 nM.*Available package size: 5,10,50,200mg

AZD 1152-HQPA is a highly potent and selective inhibitor of Aurora B, with Ki values to be 0.36 (Aurora B) and 1369 nM (Aurora A) respectively and has a high specificity versus a panel of 50 other kinases.*Available package size: 5,10,50,200mg

Hesperadin is a human Aurora B inhibitor with an IC50 of 40 nM for the prevention of the phosphorylation of substrate.*Available package size: 5,10,50,100mg

VX-680 is a potent and selective small-molecule inhibitor of the Aurora kinases.*Available package size: 25,50,100,250mg

PARP

MK-5108, also known as VX-689, is a competitive inhibitor of the ATP-binding site of aurora A kinase.*Available package size: 5,10,50,100mg

A-966492 displayed high potency against the poly(ADP-ribose) polymerase-1 (PARP-1) enzyme with a K(i) of 1 nM and an EC(50) of 1 nM in a whole cell assay.*Available package size: 5,10,50,100mg

ABT-888(Veliparib) is a potential anti-cancer drug acting as a PARP inhibitor.*Available package size: 10,50,100,200mg

A13250 Reversine

A13396 MK-8745

Cell Cycle

A10019 A-966492

A10026 ABT-888 (Veliparib)

A10045 AG-014699 (Rucaparib)

Polo-like kinases (PLKs)

Rho-Kinase (ROCKs)

A10134 BI 2536

A10381 Fasudil HCl (HA-1077)

A10046 AG14361

A10111 Olaparib (AZD2281)

A10164 BSI-201 (Iniparib)

BMN-673 is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity.*Available package size: 5,10,25,50mg

BI 2536 is a selective inhibitor of Plk1, which inhibits Plk1 enzyme activity at low nanomolar concentrations.*Available package size: 5,10,50,100mg

A10135 BI6727 (Volasertib)

A10442 GSK461364

A10452 HMN-214

A10673 ON-01910

ON-01910 is selectively cytotoxic for chronic lymphocytic leukemia cells through a dual mechanism of action involving PI3K/AKT inhibition and induction of oxidative stress.*Available package size: 5,10,50,100mg

A11146 TAK-960

TAK-960 is a novel, orally available, selective inhibitor of polo-like kinase 1, shows broad-spectrum preclinical antitumor activity.*Available package size: 5,10,50,100mg

A11438 GW843682X

A12429 MLN 0905

A13245 RO3280

AG-014699 (Rucaparib) is a PARP inhibitor that inhibits poly(ADP-ribose) polymerase (PARP) is a key enzyme in DNA repair.*Available package size: 5,25,50,100mg

BSI-201 is a potent inhibitor of PARP-1 and has been shown to cross the blood-brain barrier.*Available package size: 10,50,100,200mg

A10475 INO-1001

A10909 Tenofovir Disoproxil Fumarate

A11026 MK-4827

MK-4827 is a novel potent, orally bioavailable PARP-1 and PARP-2 inhibitor.*Available package size: 5,10mg

A11243 BMN673

A12393 AZD-2461

A12665 PJ 34 hydrochloride

A12750 UPF 1069

A13731 JW 55

Cell Cycle

Fasudil HCl is a cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM).*Available package size: 250,500mg

A10441 GSK429286A

A10928 Thiazovivin

Thiazovivin is a selective inhibitor of Rho-associated kinase (ROCK).*Available package size: 5,10,25,50mg

A11001 Y-27632 dihydrochloride


11 12

TopoisomeraseA10041 Adriamycin

A10071 Amonafide (AS1413)

A10174 Camptothecin

A10194 Cerubidine

A10345 Epirubicin Hydrochloride

A10373 Etoposide (VP-16)

A10465 Idarubicin HCl

SR 3677 dihydrochloride is a potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).*Available package size: 10,25,50,100mg

A12740 EHop-016

A13067 RKI-1447

RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.*Available package size: 5,10,25,50mg

A13785 HA-1077 dihydrochloride

Idarubicin is an anthracycline antibiotic that is an anti-leukemia agent with higher DNA binding capacity and greater cytotoxicity than daunorubicin.*Available package size: 5,10,50,100mg

MicrotubulesA10024 ABT-751

A10238 Colchicine

A10264 CYT997

A10477 Irbesartan (Avapro)

A10478 Irinotecan

A10479 Irinotecan HCl Trihydrate (Campto)

A10596 Mitoxantrone Hydrochloride

A10609 Moxifloxacin HCl

A10735 Pirarubicin

Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.*Available package size: 50,100,200mg

A10740 Podophyllotoxin

A10939 Topotecan HCl (Hycamtin)

Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death.*Available package size: 10,25,50,100mg

A11231 Exatecan mesylate

CYT997 is a novel anti-cancer vascular disrupting agent (VDA). In vitro, CYT997 is shown to potently inhibit the proliferation of vascular endothelial growth factor-stimulated human umbilical vein endothelial cells (IC(50) 3.7 ± 1.8 nM) and cause significant morphological changes at 100 nM, including membrane blebbing.*Available package size: 5,10,50,100mg

A10326 Docetaxel (Taxotere)

A10359 Epothilone A

A10360 Epothilone B (EPO906)

A11861 Flumequine

A11902 Pefloxacin mesylate

A11997 (S)-10-Hydroxycamptothecin

A12011 SN 38

SN 38 is the active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor).*Available package size: 50,100,250mg

Y-27632 is a Rho-Associated Coil Kinase (ROCK) inhibitor that increases the cloning efficiency of human embryonic stem cells (hESCs).*Available package size: 5,10,25,50mg

A11610 Y-33075

A12348 GSK 269962

A12546 NSC 23766

A12674 SR 3677 dihydrochloride

A12663 Amrubicin

A13059 Beta-Lapachone

Cell Cycle Cell Cycle

A10689 Paclitaxel (Taxol)

Paclitaxel (Taxol) is a mitotic inhibitor that stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division.*Available package size: 10,50,100,200mg

A10740 Podophyllotoxin

A10973 Vincristine sulfate

A10975 Vinflunine Tartrate

A11412 Epothilone D

Epothilone B is a macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis.*Available package size: 2,5,10,25mg

Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy.*Available package size: 1,2,5,10mg

A11449 Ixabepilone

A11617 Vinblastine

A12591 Cevipabulin (TTI-237)

A12804 Eribulin Mesylate

A13081 Fosbretabulin disodium (CA4P)

A13219 Nocodazole

A13735 CW069

A13827 CK-636

Synthases / SynthetasesA10050 Alendronate sodium hydrate

A10776 Raltitrexed (Tomudex)

A12992 HQL-79

A13583 1400W Dihydrochloride

RNA/DNA Polymerase

A10908 Tenofovir (Viread)

A11115 Abacavir

A11120 Abacavir sulfate

A11590 T-705 (Favipiravir)

A13239 Actinomycin D

A13274 Delavirdine mesylate

T-705, a substituted pyrazine compound, has been found to exhibit potent anti-influenza virus activity in vitro and in vivo.*Available package size: 10,25,50,100mg

TelomeraseA10140 BIBR 1532

Ligases

A10884 TAME

BIBR 1532 is a selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively).*Available package size: 10,50,100,200mg

A10240 Costunolide

A11999 Betulinic acid

A13093 Amsacrine

A13206 GENZ-644282

Reverse Transcriptase

A10039 Adefovir dipivoxil

A10349 Emtricitabine

A10639 Nevirapine (Viramune)

A10908 Tenofovir (Viread)


13 14

MitosisA13872 INH1

Lersivirine (UK-453,061) is a next-generation nonnucleoside reverse transcriptase inhibitor, active against wild-type HIV-1 and several nonnucleoside reverse transcriptase inhibitor-resistant strains.*Available package size: 5,10,25,50mg

Tenofovir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood.*Available package size: 10,25,50,100mg

A10909 Tenofovir Disoproxil Fumarate

A11115 Abacavir

A11120 Abacavir sulfate

A12443 MK-1439

MK-1439 is a non-nucleoside reverse transcriptase inhibitor.*Available package size: 5,10,25,50mg

A12587 Dapivirine

A12667 Lersivirine (UK-453061)

Cell Metabolism

Cell Cycle

Cytochrome P450A10020 Abiraterone (CB-7598)

A10081 Apigenin

A10102 Avasimibe (CI-1011)

A10120 Baicalein

A10200 Chloramphenicol

A10234 Clotrimazole

A10498 Ketoconazole

A10578 Methoxsalen (Oxsoralen)

A10625 Naringenin

A10853 Sodium Danshensu

A10978 Voriconazole (Vfend)

A11044 TAK-700 (Orteronel)

Abiraterone (CB-7598) inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1), an enzyme which is expressed in testicular, adrenal, and prostatic tumor tissues.*Available package size: 5,10,50,100mg

TAK-700 (Orteronel) is an oral, non-steroidal androgen synthesis inhibitor that selectively inhibits the 17,20 lyase enzyme.*Available package size: 5,10,50,100mg

A11058 Abiraterone Acetate (CB7630)

A11138 TOK-001 (Galeterone)

A11144 TH-302

A11277 Cobicistat(GS-9350)

A11481 Luliconazole

A11865 Hydroxyflutamide

A11977 TMS

A12544 PF 4981517

A13361 ABT

A13365 3-Cyano-7-ethoxycoumarin

TOK-001 (Galeterone) is both an androgen receptor antagonist and CYP17A1 inhibitor.*Available package size: 5,10,50,100mg

β-AmyloidA10312 Dimebon dihydrochloride

A12647 Ro 90-7501

Phosphodiesterases (PDEs)A10216 Cilomilast (SB-207499)

A10217 Cilostazol

A10449 Hesperetin

A10464 Icariin

A10541 Luteolin

A10592 Milrinone (Primacor)

A10733 Pimobendan (Vetmedin)

A10804 Roflumilast

A10805 Rolipram

A10965 Vardenafil

A11019 Ibudilast (KC-404)

A11073 GSK256066

A11191 PF-2545920

A11289 Apremilast (CC 10004)

A11326 Bay 60-7550

A12550 Zardaverine

A12619 Avanafil

A12776 AN2728

A13121 PF-04447943

A13722 Deltarasin-HClCilomilast is orally active and acts as a selective Phosphodiesterase-4 i n h i b i t o r w i t h a n t i i n f l a m m a t o r y e f f e c t s t h a t t a r g e t bronchoconstriction, mucus hypersecretion, and airway remodeling associated with COPD.*Available package size: 5,10,50,100mg

Pimobendan (Vetmedin) is a calcium sensitizer with positive inotropic and vasodilator effects. It is also a selective inhibitor of phosphodiesterase III (PDE3).*Available package size: 5,10,50,100mg

Ibudilast, a pharmacologic phosphodiesterase inhibitor, prevents human immunodeficiency Virus-1 Tat-Mediated activation of microglial cells.*Available package size: 10,50,100mg

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.*Available package size: 2,5,10,25mg

Deltarasin is a novel small molecule inhibiting the KRAS PDEδ interaction and thus impairing oncogenic KRAS signalling.*Available package size: 5,10,25mg

A13366 Mephenytoin

A13367 Methoxyresorufin

Cell Metabolism

Hydroxylases

A10485 Isotretinoin

A10542 LX 1606 Hippurate

A10637 Nepicastat (free base) (SYN-117)

LX 1606 hippurate is an orally bioavailable, small-molecule, t r y p to p h a n hyd rox yl a s e ( T P H ) i n h i b i to r w i t h p o te n t i a l antiserotonergic activity.*Available package size: 5,10,50,100mg

Nepicastat is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.*Available package size: 5,10,50,100mg


15 16

Dihydrofolate reductase (DHFR)A10021 Methotrexate (Abitrexate)

A10655 NSC 131463 (DAMPA)

A10707 Pemetrexed (Alimta)

A12796 Trimetrexate

Dehydrogenases

A10780 Ranolazine

A11403 MK-8245

A11682 Gimeracil

A11786 CPI-613

A11172 Nepicastat hydrochloride

A11183 PF-3845

A11785 LX 1606

A12833 Ro 61-8048

A13363 Metyrapone

A13998 DMOG

Trimetrexate is a quinazoline derivative. It is a dihydrofolate reductase inhibitor.*Available package size: 5,10,25,50mg

A12385 CGP 3466B maleate

A12442 Brequinar

A12902 AGI-5198 (IDH-C35)

CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities.*Available package size: 5,10,25,50mg

Cyclooxygenase (COX)

A10030 Acetaminophen

A10090 Asaraldehyde (Asaronaldehyde)

A10193 Celecoxib

A10304 Diclofenac sodium

A10382 Febuxostat (TEI-6720)

A10461 Ibuprofen (Advil)

A10462 Ibuprofen Lysine (NeoProfen)

A10474 Indomethacin (Indocid, Indocin)

A10623 Naproxen sodium

A10720 Phenylbutazone

A10736 Piroxicam (Feldene)

A12903 AGI-6780

A12925 JK 184

AGI-5198, also know as IDH-C35, is the a very potent and selective mutant IDH1 inhibitor that was shown to potential anticancer activity.*Available package size: 5,10,25,50mg

Piroxicam is an effective and potent inhibitor of prostaglandin synthesis and a Cox-1 and Cox-2 inhibitor.*Available package size: 250,500mg

A10749 Pravadoline (WIN 48098)

A10878 Sulindac (Clinoril)

A11292 Alvimopan (ADL 8-2698)

A11464 Iguratimod (T 614)

A11686 Flunixin meglumine

A11692 Acemetacin (Emflex)

A11693 Tolfenamic acid

A11694 Nimesulide

A11695 Lornoxicam (Xefo)

A11697 Licofelone

Licofelone is a dual COX/LOX inhibitor, being considered as a treatment for osteoarthritis. It may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase). Licofelone is the first drug to inhibit both.*Available package size: 5,10,50,100mg

A11906 Phenacetin

A11918 Rofecoxib (Vioxx)

A11986 ATB-337

A12434 (S)-(+)-Flurbiprofen

A13116 NS-398

NS-398 is a COX-2 inhibitor used in the study of the function of cyclooxygenases.*Available package size: 10,25,50,100mg

A13244 Bromfenac sodium

A13332 FK 3311

A13342 Valdecoxib

A13572 Parecoxib

AntimetaboliteA10177 Capecitabine (Xeloda)

Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. *Available package size: 1,5g

A10183 Carmofur

A10223 Cladribine

A10251 Flupirtine maleate

Flupirtine maleate is a Non-opioid analgesic with muscle relaxant properties.*Available package size: 10,25,100mg

A10286 Daphnetin

A10292 Decitabine

Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.*Available package size: 10,25,50,100mg

Cell MetabolismCell Metabolism

A10395 Fludarabine Phosphate (Fludara)

A10396 Fludarabine (Fludara)

Histone Deacetylase (HDAC)

A10122 Belinostat (PXD101)

Belinostat (PXD101) is a HDAC inhibitor that inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM.*Available package size: 10,50,100,200mg

A10179 Carbamazepine

A10246 CUDC-101

CUDC-101 is a novel compound which inhibits multiple targets, which is designed to inhibit HDAC, EGFR and Her2.*Available package size: 10,50,100,200mg

A10337 Droxinostat

A10488 ITF2357 (Givinostat)

A10492 JNJ-26481585

A10516 LAQ824 (NVP-LAQ824)

LAQ824 (NVP-LAQ824) is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.*Available package size: 10,50,100mg

A10518 LBH589 (Panobinostat)

A10560 MC1568

MC1568 is a member of HDAC inhibitors that inhibits the histone deacetylase class II by modifying the genetic expression of various important genes of cell cycle mostly at G1 phase, resulting in the death of breast cancer cells by apoptosis.*Available package size: 10,25,50,100mg

A10586 MGCD0103 (Mocetinostat)

A10611 MS-275 (Entinostat)

A10700 PCI-24781

A10764 Pyroxamide (NSC 696085)

A10830 SB939

A10947 Trichostatin-A (TSA)


17 18A10954 Tubacin

A10979 Vorinostat (SAHA)

A11037 AR-42 (HDAC-42)

A11042 Tubastatin A HCl

A11152 PCI-34051

PCI-34051 is a specific and potent histone deacetylase 8 (HDAC8) inhibitor, with >200-fold selectivity over the other HDAC isoforms.*Available package size: 10,25,50,100mg

A11153 CUDC-907

A11920 Romidepsin (FK228 ,Depsipeptide)

A11940 ACY-1215 (Rocilinostat)

A11964 CI994 (Tacedinaline)

CI-994 is a histone deacetylase (HDAC) inhibitor and induces histone hyperacetylation in living cells.*Available package size: 10,50,100mg

A12556 Resminostat

Sir2-like Family Deacetylases (sirtuins)A10377 EX 527

A12722 Scriptaid

A12745 Apicidin

A12911 BRD9757

A13218 RGFP966

Resminostat, also known as RAS2410, is a potent inhibitor of histone deacetylase (HDAC) classes I and II. It binds to and inhibits HDACs leading to an accumulation of highly acetylated histones.*Available package size: 10,25,50,100mg

Kinesin Spindle ProteinA10486 Ispinesib (SB-715992)

Monoamine Oxidase (MAO)A10078 Aniracetam

A10818 Safinamide Mesylate (FCE28073)

A11722 Rasagiline mesylate

Factor XaA10082 Apixaban (BMS-562247-01)

A10785 Resveratrol

A10862 SRT1720

EX 527 is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor*Available package size: 5,10,25,100mg

SRT1720 is an inhibitor developed intended as a small-molecule activator of the sirtuin subtype SIRT1.*Available package size: 5,10,50,200mg

A12527 Inauhzin

A12904 AK-7

Rasagiline is an irreversible inhibitor of monoamine oxidase used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.*Available package size: 50,100mg

A11777 SL251188

A11885 Moclobemide

A13294 Safinamide

A13353 Bifemelane hydrochloride

Apixaban is an anticoagulant for the prevention of venous thromboembolism and venous thromboembolic events.*Available package size: 5,10,50,100mg

A10158 BMS-740808

A10800 Rivaroxaban (Xarelto)

A12411 Rivaroxaban Diol

A12518 Betrixaban

A12870 Razaxaban

A12871 Letaxaban (TAK-442)

A13878 ABT333


DNA, RNA and Protein SynthesisA10036 Cycloheximide (Actidione)

A10152 Bleomycin sulfate

A10182 Carboplatin

A10221 Cisplatin

A10224 Clafen (Cyclophosphamide)

A10228 Clofarabine

A10281 Dacarbazine

A10346 Oxaliplatin (Eloxatin)

A10392 Floxuridine

A10466 Ifosfamide

A10532 Lincomycin hydrochloride (U-10149A)

A10568 Mercaptopurine

A10597 Mizoribine

A10632 Nelarabine (Arranon)

A10828 SB 743921

A11050 Arry-520

A11170 AZ 3146

A11976 Monastrol

Ispinesib (SB-715992) is a potent inhibitor of kinesin spindle protein, a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis.*Available package size: 5,10,50,100mg

AZ 3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). It interferes with chromosome alignment and overrides spindle assembly checkpoint and also Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.*Available package size: 5,10,50,100mg

A11065 CX-5461

CX-5461 is a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage.*Available package size: 5,10,50,100mg

A11147 CCT239065

A11179 NSC-207895 (XI-006)

A11803 Azithromycin (Zithromax)

A11804 Adenine sulfate

A12326 INNO-206 (Aldoxorubicin)

Aldoxorubicin, also known as INNO-206, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity.*Available package size: 10,25,50,100mg

A12409 Epirubicin

CYP17A11044 TAK-700 (Orteronel)

A11138 TOK-001 (Galeterone)

Epirubicin is a cell-permeable antitumor antibiotic. A stereoisomer of Doxorubicin that exhibits reduced cardiotoxicity. Epirubicin’s antitumor actions are mediated by targeting and inhibiting Topo II (topoisomerase II).*Available package size: 10,25,50,100mg

A12890 Thiostrepton

TOK-001 (Galeterone) is both an androgen receptor antagonist and CYP17A1 inhibitor.*Available package size: 5,10,50,100mg


19 20

Lipid Metabolism

A11230 PF 429242

FAAHA11049 URB597

CETP

PF 429242 is a reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease.*Available package size: 10,25,50,100mg

A11242 Torcetrapib (CP-529414)

A12318 SC-26196

URB597 is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH).*Available package size: 5,25,50,100mg

A12420 JNJ 1661010

JNJ 1661010 is a selective and reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50 = 12nM).*Available package size: 10,25,50,100mg

A11084 Anacetrapib (MK-0859)

DNA MethyltransferasesA10105 Azacitidine(Vidaza)

A10292 Decitabine

A12744 SGI-110

HMG-CoA Reductase

A10737 Pitavastatin calcium (Livalo)

Neuronal MetabolismA12404 ONO 2506

A13004 INCB024360

A12916 Ferrostatin-1 (ethyl ester)

A13247 Ferrostatin-1 (Fer-1)

A13822 Erastin

IDO

Ferroptosis

Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis.*Available package size: 10,25,50,100mg

A11800 Atorvastatin calcium

A11877 Lovastatin (Mevacor)

A11912 Pravastatin sodium

A13709 Mevastatin

A13743 Atorvastatin

I N C B 0 2 4 3 6 0 i s a n o ra l ly ava i l a b l e hyd rox ya m i d i n e a n d inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities.*Available package size: 5,10,25,50mg

ONO 2506 inhibits S100B synthesis in activated cultured astrocytes.*Available package size: 10,25,50,100mg

A11213 JTT-705 (Dalcetrapib)

A11397 Evacetrapib (LY2484595)

Anacetrapib (MK-0859) is a CETP inhibitor being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease.*Available package size: 5,10,50,100mg

Phospholipases

A10206 Chlorpromazine hydrochloride

A10548 LY315920 (Varespladib)

LY315920 (Varespladib) is an inhibitor of the IIa, V, and X isoforms of secretory phospholipase A2 (sPLA2).*Available package size: 5,10,50,100mg

PI3K / Akt / mTOR


AktA10003 MK-2206 dihydrochloride

A10094 AT7867

AT7867 is a novel and potent inhibitor of both AKT and the downstream kinase p70 S6 kinase (p70S6K) and also of protein kinase A.*Available package size: 10,25,50,100mg

A10453 Honokiol

A10709 Perifosine (NSC-639966)

A11024 PF-04691502

A11030 GSK690693

A11031 CCT128930

A11032 PHT-427

A11033 Triciribine phosphate (NSC-280594)

A11034 A-674563

A11246 GDC-0068

A11286 AKT inhibitor VIII (AKTI-1/2)

A11287 A-443654

A11759 AZD5363

A12877 KP372-1

A13210 Triciribine

Triciribine, also known as API-2, suppresses the phosphorylation level and kinase activity of Akt.*Available package size: 10,25,50,100mg

PI3-Kinase (PI3K)A10088 AS-605240

A10112 AZD6482

A10133 BEZ235 (NVP-BEZ235)

A10172 CAL-101 (GS-1101)

A10421 GDC-0941

A10438 GSK1059615

A10463 IC-87114

A13460 Deguelin

IC-87114 was the first isoform-selective PI3K inhibitor: p110M-NM-4(IC50 = 0.13 M-BM-5M) vs. p110M-NM-1(IC50 = 200 M-BM-5M), p110M-NM-2(IC50 = 16 M-BM-5M) and p110M-NM-3(IC50 = 61 M-BM-5M).*Available package size: 5,10,25,100mg

A10547 LY294002

A10693 Palomid 529 (P529)

Palomid 529 is a dual TORC1/2 inhibitor of the PI3K/Akt/mTOR pathway having broad activity in angiogenesis and cellular proliferation*Available package size: 10,50,100,200mg

A10727 PIK-293

A10728 PIK-294

A11409 Cyproterone acetate

A13515 TAK-700 (salt)


21 22

PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110δ-selective inhibitors that has been reported.*Available package size: 5,10,50,100mg

A10729 PIK-75

A10730 PIK-90

A10731 PIK-93

A10765 Quercetin dihydrate (Sophoretin)

A10766 Quercetin (Sophoretin)

A10922 TG100-115

TG100-115 inhibits PI3K γ and -δ(IC50 values of 83 and 235 nM, respectively).*Available package size: 5,10,25,100mg

A10923 TGX-221

A10995 XL147

A10997 XL765

A11014 ZSTK474

Z S T K 4 7 4 i s a n AT P - c o m p e t i t i v e i n h i b i t o r o f c l a s s I phosphatidylinositol 3 kinase isoforms.*Available package size: 10,25,50,100mg

A11016 BKM120 (NVP-BKM120)

A11023 GDC-0980 (RG7422)

A11035 GSK2126458

A11064 YM201636

A11089 PKI-402

A11098 NU-7441 (KU-57788)

A11099 AS-252424

AS-252424 is a potent inhibitor of PI3K with selectivity for the γ isoform. It inhibits human recombinant PI3Kγ, α, β, and δ with IC50 values of 30, 940, 20,000, and 20,000 nM respectively.*Available package size: 5,10,50,100mg

A11151 3-Methyladenine

A11161 Wortmannin

A11162 NVP-BGT226

A11169 CH5132799

A11196 CAY10505

A11197 AS-604850

AS-604850 inhibited MCP-1-mediated monocyte chemotaxis with an IC50 value of 21 µM and reduced RANTES-induced peritoneal neutrophil recruitment in a murine model of leukocyte chemotaxis with an ED50 value of 42.4 mg/kg.*Available package size: 5,10,50,100mg

A11198 D-106669

A11202 A66

A11207 PP121

A11261 PX-866

A11328 BYL719

PP121 is a dual inhibitor of receptor tyrosine kinases (RTKs) (IC50 < 0.02 μM for Abl, Src, VEGFR-2 and PDGFR) and PI 3-K family kinases (IC50 < 0.06 μM for p110α, DNA-PK and mTOR).*Available package size: 10,25,50,100mg

PX-866 is a small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic activity.*Available package size: 5,10,25,50mg

BLY719 is an orally bioavailable phosph-atidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.*Available package size: 5,10,25,50mg

A11363 CZC24832

A11511 NVP-BAG956

A11766 BAY 80-6946

A11784 GSK2636771

A11956 TG 100713

A12422 IPI-145

A12480 VS-5584

A12704 SF1126

A12831 GDC-0032

A12935 PF-04979064

IPI-145, also known as INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities.*Available package size: 5,10,25,50mg

PF-04979064 is a highly potent and orally bioavailable PI3K/mTOR dual inhibitor.*Available package size: 2,5,10mg

A13021 HS-173

A13224 KU 0060648

A13879 CNX-1351

PI3K / Akt / mTOR PI3K / Akt / mTOR

mTOR

A10114 AZD8055

AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.*Available package size: 10,25,50,100mg

A10295 Deforolimus (Ridaforolimus)

A10374 Everolimus (RAD001)

A10505 KU-0063794

A10746 PP242

KU-0063794 is a selective inhibitor of mammalian target of rapamycin (mTOR) (IC50 ~10 nM for mTORC1 and mTORC2 respectively).*Available package size: 5,25,50,100mg

PP242 is a potent and selective mTOR inhibitor in both mTORC1 and mTORC2.*Available package size: 5,10,50,100mg

A10782 Rapamycin (Sirolimus)

A10906 Temsirolimus (Torisel)

A10989 WYE-354

WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of PI3K α (IC50 = 1026 nM) and other kinases.*Available package size: 5,10,25,50mg

A11038 WYE-125132 (WYE-132)

A11056 OSI-027

A11079 PKI-587

A11187 WYE-687

A11188 WAY-600

A11303 AZD2014

AZD2014 is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor.*Available package size: 5,10,25,50mg

INK 128 is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity.*Available package size: 5,10,25,50mg

A11443 GDC-0349

A11461 INK 128


23 24

DNA-dependent protein kinase (DNA-PK)A10726 PI-103

Ribosomal S6 protein kinases (RSK)

A11160 SL 0101-1

A11423 FMK

A11755 PF 4708671

A12452 BI-D1870

PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110α), and mTOR.*Available package size: 5,10,25,50mg

A11098 NU-7441 (KU-57788)

A11778 Compound 401

A12752 NU7026PDK1A10681 OSU-03012

A11148 BX-795

A11149 BX-912

BX-795 is a potent PDK1 inhibitor that blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines in culture or induced apoptosis.*Available package size: 10,25,50,100mg

A11511 NVP-BAG956

A12767 GSK 2334470

A13484 PS 48

A11587 Torin 1

A11950 Zotarolimus

A12395 XL388

Torin 2 is a potent and selective mTOR inhibitor (IC50 = 2.1 nM). Displays 800-fold cellular selectivity for mTOR over PI3K (cellular EC50 values are 0.25 and 200 nM for mTOR and PI3K respectively).*Available package size: 10,25,50,100mg

Receptor Tyrosine KinasesEGFR/HER2A10043 AEE788

A10047 AG-490


A10062 AST-6

A10116 AZD8931

A10141 BIBW2992 (Afatinib)

A10210 Chrysophanic acid (Chrysophanol)

A10211 Canertinib (CI-1033)

A10242 CP-724714

A10362 Erlotinib Hydrochloride

A10422 Gefitinib (Iressa)

A10514 Lapatinib Ditosylate

A10612 Mubritinib (TAK 165)

A10638 Neratinib (HKI-272)

A10678 OSI-420

A10702 PD153035 (HCl salt)

A10706 Pelitinib (EKB-569)

A10990 WZ3146

A10991 WZ4002

A10992 WZ8040

A11022 AG-1478 (Tyrphostin AG-1478)

A11027 Arry-380

A11028 AV-412

A11051 PF299804

A11057 XL647

A11155 AST-1306

A11158 ARRY334543

A11209 BMS 599626 (AC480)

A11236 TAK-285

A11263 BMS-690514

A11334 BIBX 1382


FGFRA10703 PD173074

A11075 AZD4547

A11159 BGJ398 (NVP-BGJ398)

A11244 LY 2874455

PDGFRA10504 KRN 633

A10880 Sunitinib Malate

A10903 Telatinib (BAY 57-9352)

A11052 Crenolanib (CP-868596)

A11350 CP-673451

A11581 Toceranib (PHA 291639, SU 11654)

A11753 MK-2461


VEGFR

A10025 Linifanib (ABT-869)

A10049 Albendazole

A10101 Tivozanib (AV-951)

A10103 Axitinib

A10137 Bibf1120 (Vargatef)

A10162 Brivanib alaninate (BMS-582664)

A10185 Cediranib (AZD2171)

A10204 Chloroxine

A10248 CYC116

A10254 Brivanib (BMS-540215)

A10259 Imatinib (Gleevec)

A10340 E7080 (Lenvatinib)

A10495 Kaempferol

A10502 Ki8751

A10504 KRN 633

A10608 Motesanib Diphosphate (AMG-706)

A10699 Pazopanib Hydrochloride (GW786034)

A10893 Taxifolin

A10953 TSU-68 (SU6668)

A11586 Torin 2

PI3K / Akt / mTOR

A11558 SU-5402

A11752 Lapatinib (free base)

A11948 AP26113

A11949 AG-17

A12448 Butein

A12650 PKC 412

A12867 CGP-52411

A12868 ARRY-543


A13681 AZD-9291

A13718 Icotinib Hydrochloride

A13755 CNX-2006

A13825 Icotinib

A10963 Vandetanib (ZD6474)

A10967 Vatalanib (PTK787) 2HCl


A11263 BMS-690514



A11496 Motesanib (AMG706)

A11557 SU14813

A11772 CP-547632




A12027 (-)-Catechin gallate

A12437 SU 5416 (Semaxinib)

A13234 SKLB1002

A13377 SAR131675

A13465 SKLB610

A13966 TPT-260 (Dihydrochloride)

Type 1 insulin-like growth factor receptor (IGF-1R)A10440 GSK1904529A

A10658 NVP-ADW742

A11021 NVP-AEW541

NVP-AEW541 is a selective IGF-1R kinase inhibitor that inhibits the autophosphorylation activity of IGF-1R (IC50 = 0.086 uM) and prevents IGF-1-mediated survival and proliferation of MCF-7 cells (IC50 = 0.16 and 1.64 uM, respectively).*Available package size: 2,5,10,25mg

A11053 OSI-906

OSI-906 is a potential first-in-class selective small molecule, dual kinase inhibitor of both insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR).*Available package size: 5,10,50,100mg

A11054 BMS-536924

A11059 BMS-754807

A11400 AG-1024 (Tyrphostin)

A11951 PQ 401

A12195 Picropodophyllin

A13069 XL-228

Receptor Tyrosine Kinases


25 26

FLT3 (FMS-like tyrosine kinase 3)A10027 AC220 (Quizartinib)

c-META10063 AMG 208

A10153 BMS-777607

A10198 Dovitinib Dilactic acid

A10352 ENMD-2076

A10508 KW-2449

A10887 Tandutinib (MLN518)

A11411 Dovitinib (TKI-258)

A12427 TCS 359

A13454 SB1317 (TG-02)

AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor with IC50 of 0.56 ± 0.3 nM and >10 mM for MC4-11 and A375, respectively.*Available package size: 5,10,50,200mg

ENMD-2076 is a novel, orally-active antimitotic and antiangiogenic molecule inhibits Aurora A as well as tyrosine kinases that drive tumor vascularization, including VEGFR2 (KDR), PDGFR and the FGF receptors.*Available package size: 5,10,50,100mg

Dovitinib is a small-molecule multitargeted receptor tyrosine kinase inhibitor, which inhibits Ba/F3 cells transformed to IL3 independence by ZNF198-FGFR1 or BCR-FGFR1 with IC50 values of 150 nM and 90 nM, respectively.*Available package size: 10,25,50,100mg

BMS-777607 is a MET tyrosine kinase inhibitor that binds to c-Met protein, or HGFR, preventing binding of HGF and disrupting the MET signaling pathway.*Available package size: 5,10,50,100mg

A10154 BMS-794833

A10493 JNJ-38877605

A10587 MGCD-265

ALK

A10662 TAE684

MGCD265 is a multitargeted tyrosine kinase inhibitor that binds to and inhibits the phosphorylation of several RTKs, including the c-Met receptor (HGFR); the Tek/Tie-2 receptor; VEGFR types 1, 2, and 3; and MST1R.*Available package size: 5,10,50,100mg

A10610 MP470 (MP-470)

A10711 PF-04217903

A10713 PHA-665752

A10839 SGX-523

A10869 SU11274

A10998 Foretinib (GSK1363089, XL880)

A11055 AMG-458

A11087 ARQ 197

ARQ-197 is a selective inhibitor of the c-Met receptor tyrosine kinase.*Available package size: 10,50,100,200mg

A11132 INCB28060

INCB28060, a novel inhibitor of c-MET kinase. INCB28060 exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10,000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines.*Available package size: 5,10,25,50mg

A11150 NVP-BVU972

A11257 EMD-1214063


TAE684 is a inhibitor of ALK and also a potent inhibitor of LRRK2 kinase activity (IC(50) of 7.8nM against wild-type LRRK2, 6.1nM against the G2019S mutant).*Available package size: 5,10,50,100mg

A10712 PF-2341066 (Crizotinib)

A10826 SB 431542

A11083 GW788388

A11134 CH5424802

A11175 GSK1838705A

A11205 LDN193189

LDN193189 is a highly potent small molecule BMP inhibitor that inhibits BMP type I receptors ALK2 (IC50: 5 nM), ALK3 (IC50: 30 nM) and ALK6 (TGFβ1/BMP signaling) and subsequent SMAD phosphorylation.*Available package size: 2,5,25,50mg

BCR-ABL

A11773 ASP3026

A11948 AP26113

A13065 AZD3463

A13238 LDK-378

LDK378 is a highly selective, orally bioavailable and ATP-competitive small molecule inhibitor of ALK (Anaplastic Lymphoma Kinase), a receptor tyrosine kinase considered to be an important lung cancer drug target.*Available package size: 5,10,25,50mg

A13744 CEP-28122

A10080 AP24534 (Ponatinib)

AP24534 (Ponatinib) is a potent multi-kinase and pan-BCR-ABL inhibitor.*Available package size: 10,25,50,100mg

A10119 Bafetinib (INNO-406)

A10408 FTY720 (Fingolimod)

A10468 Imatinib Mesylate

A10644 Nilotinib (AMN-107)

Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.*Available package size: 25,50,100,200mg

A10988 WP1130 ( Degrasyn )

A11200 DCC-2036 (Rebastinib)

A11439 GNF 2

GNF 2 is a Bcr-abl inhibitor that inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells.*Available package size: 10,25,50mg

SRC

A13120 PD173955

A13237 GNF-5

FAKA11142 PF 431396

A11192 PF-562271

PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities.*Available package size: 5,10,50,100mg

A11235 PF 573228

A11929 PF-04554878

A12580 PF-00562271




27 28

A10290 Dasatinib (BMS-354825)

A11020 PCI-32765

PCI-32765 is an orally bioavailable small-molecule inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.*Available package size: 5,10,25,100mg

A11177 KX2-391

A12214 KX1-004

A12417 MLR 1023

A12723 PP2

A12724 PP1

PP2 is a selective inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 4 and 5 nM respectively). Displays > 10000-fold selectivity over ZAP-70 and JAK2. Moderately inhibits CSK (IC50 = 0.73 μM).*Available package size: 10,25,50,100mg

A13232 1-NA-PP1

A13290 A-419259

A13573 PP1 Analog II, 1NM-PP1

A13821 CGP77675

c-Kit

Spleen tyrosine kinase (Syk)

A10250 Regorafenib (BAY 73-4506)

A10558 Masitinib (AB1010)

A10161 Bosutinib (SKI-606)

Masitinib (AB1010) is a protein tyrosine kinase inhibitor.*Available package size: 10,25,50,100mg

A10679 OSI-930

A11518 Pazopanib(GW-786034)

Bosutinib (SKI-606) is a tyrosine kinase inhibitor undergoing research for use in the treatment of cancer.*Available package size: 10,50,100,200mg

A10769 R406

R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.*Available package size: 2,5,10,25mg

A10770 R406 (freebase)

A10771 R935788

A11320 BAY 61-3606

A11926 R788 (Fostamatinib)

A11952 P505-15

A12162 Piceatannol

A12731 PRT062607 HCL

A13884 GS-9973

GS-9973 is an oral inhibitor of spleen tyrosine kinase (Syk), with potential antineoplastic activity.*Available package size: 10,25,50,100mg

Tie-2A10932 Tie2 kinase inhibitor

A13456 AMG-Tie2-1

Bone Morphogenetic Proteins (BMP)

AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC50 <1 nM).*Available package size: 5,10,25,50mg

A10108 Saracatinib (AZD0530)

Saracatinib (AZD0530) is a highly selective, orally available, dual-specific Src/Abl kinase inhibitor with IC50 of 2.7 and 30 nM for c-Src and Abl kinase, respectively.*Available package size: 10,25,100,200mg

A10959 UK-383367

Bruton's tyrosine kinaseA11020 PCI-32765

A11348 CGI1746

A12706 GDC-0834

A13202 AVL-292

UK-383367 is a potent and selective inhibitor of BMP-1.*Available package size: 10,25,50,100mg

A12820 DMH-1

A12821 LDN-212854

AVL-292 is a highly selective, covalent Btk inhibitor.*Available package size: 5,10,25,50mg

A13233 CNX-774

CNX-774 is a potent Btk inhibitor (IC50 < 1 nM).*Available package size: 5,10,25,50mg

Axl

Tyrosine kinase

A10153 BMS-777607


A13741 R428

A11472 Ki 20227

A13587 AG-1288

A13589 AG 957

Trk Receptors

A13730 GNF 5837

GNF-5837 is a potent, selective, and orally bioavailable pan-TRK inhibitor that inhibited tumor growth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF.*Available package size: 10,25,50,100mg

Tyrphostin AG 957 is a potent tyrosine kinase inhibitor. Selectively blocks the tyrosine kinase activity of human p210bcr-abl (Ki = 750 nM) over p140c-abl (Ki = 10 μM).*Available package size: 5,10,25,50mg

NF-kB/IkBNF-kBA10293 Deferasirox

Deferasirox is a rationally-designed oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias.*Available package size: 5,10,25,50mg

A11318 BMS 345541

A11338 Bay 65-1942 HCl

A11339 Bay 65-1942

A11821 Bindarit

A12669 Teglarinad chloride




29 30

Cytokines

IKK

A10881 Suplatast tosilate

A12548 VGX-1027

A10535 Lomustine (CeeNU)

A11579 TPCA-1

A12746 SC-514

QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling.*Available package size: 5,10,25,50mg

SC-514 is an orally active, ATP-competitive IKKβ inhibitor (IC50 = 3 - 12 μM) that displays > 10-fold selectivity over 28 other kinases including JNK, p38, MK2 and ERK.*Available package size: 10,25,50,100mg

A12836 IKK-16

A12837 IMD 0354

A13108 PHA 408

A12748 QNZ

JAK / StatJAKA10095 AT9283

A10104 AZ-960

A10110 AZD1480

A10241 CP-690550 (Tofacitinib citrate)

A10263 Cyt387

AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM.*Available package size: 5,10,50,200mg

A10546 LY2784544

A11041 INCB018424 (Ruxolitinib)

A11082 TG-101348

A11180 TG101209

A11193 NVP-BSK805

A11241 BMS-911543

A11329 Baricitinib (LY3009104)

A11795 WP1066

A12394 XL019

CYT387 is an inhibitor of Janus kinases JAK1 and JAK2, acting as an ATP competitor with IC50 values of 11 and 18 nM, respectively.*Available package size: 10,25,50,200mg

A12808 CEP33779

A13082 PF-03394197 (oclacitinib)

A13162 GLPG0634

A13454 SB1317 (TG-02)

A13457 JAK Inhibitor I

A14049 WHI-P 154

Stat

Pim Kinase

A10838 SGI-1776 (free base)

A11945 SMI-4a

A11967 TCS PIM-1 4a

A12896 CX-6258

A10244 Cryptotanshinone

A10395 Fludarabine Phosphate (Fludara)

A10396 Fludarabine (Fludara)

A10817 S3I-201 (NSC 74859)

S3I-201 (NSC 74859) is a novel inhibitor of Stat3 that inhibits Stat3, Stat3 complex formation and Stat3-DNA binding activity in vitro (IC50 = 86 ± 33 µM) and Stat3-dependent transcriptional activities.*Available package size: 5,10,50,100mg

NF-kB/IkB

TGF-β / SmadTGF-β�/ Smad Inhibitors

A10827 SB 525334

Protein Kinase C (PKC)

A10196 Chelerythrine Chloride

A10356 LY317615 (Enzastaurin)

Protein Kinase AA11935 H 89 dihydrochloride

Protein kinase D (PKD)

A12416 CID 2011756

A12423 kb NB 142-70

A13804 CID 755673

H 89 dihydrochloride is a cell-permeable, selective, reversible, ATP-competitive and potent inhibitor of protein kinase.*Available package size: 10,,25,50,100mg

A11010 Zoledronic Acid

A11060 CX-4945 (Silmitasertib)

A11554 Sotrastaurin (AEB071)

Sotrastaurin is a protein kinase C inhibitor for the prevention of transplant rejection and treatment of psoriasis.*Available package size: 5,10,25,50mg

SB525334 is a selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC50 = 14.3 nM). Inhibits TGF-β1-induced smad2/3 nuclear localization and TGF-βRI-induced mRNA expression in kidney cells.*Available package size: 5,10,50,100mg

A11017 LY2157299

A11133 LY2109761

A11157 SB-505124

SB-505124 is a selective inhibitor of transforming growth factor-β type I receptor (ALK5), ALK4 and ALK7 (IC50 values are 47 and 129 nM for ALK5 and ALK4 respectively).*Available package size: 5,25,50,100mg

A11405 Astragaloside A

A11762 RepSox (SJN 2511)

A12358 A 83-01

A12924 ITD-1

TGF-β / Smad

A12399 Ruboxistaurin (LY333531)

A12419 Go 6976

A13094 alpha-Amyloid Precursor Protein Modulator

A13197 GF 109203X

ProteasesCaspaseA10984 VX-765

A11090 PAC-1

A11944 Apoptosis Activator 2

A12373 Z-VAD-FMK

A13070 LY573636 (Tasisulam)

ProteasomeA10085 Artemether (SM-224)

A10160 Bortezomib (Velcade)

A10284 Danoprevir (RG7227)

A10320 Disulfiram

A10600 MLN2238


31 32A10602 MLN9708

MLN9708 is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome.*Available package size: 5,10,50,100mg

A10617 Nafamostat mesylate

A11043 MG-132

MG-132 is a potent cell-permeable inhibitor of proteasome (IC50 = 100 nM) and calpain (IC50 = 1.2 μM).*Available package size: 10,25,50,100mg

A11145 CEP-18770

CEP-18770 is a novel orally active proteasome inhibitor with a favorable tumor selectivity profile for the treatment of MM and other malignancies responsive to proteasome inhibition.*Available package size: 5,10,50,100mg

A11278 PR-171 (Carfilzomib)

PR-171 (Carfilzomib) is a tetrapeptide epoxyketone and a selective proteasome inhibitor. It is an analog of epoxomicin.*Available package size: 5,10,25,50mg

HCV ProteaseA10159 BMS-790052

A10902 Telaprevir (VX-950)

A10980 VX-222

A11522 Pralatrexate

A12003 (-)-Gallocatechin

A12768 Lactacystin

A12933 P 22077

A13711 Gliotoxin

A14048 PSI

VX-222 is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase that is being investigated for the treatment of hepatitis C virus infection.*Available package size: 5,10,50,100mg

A11295 Asunaprevir (BMS-650032)

Asunaprevir is an inhibitor of the viral enzyme serine protease NS3.*Available package size: 5,10,25,50mg

A11332 Boceprevir (SCH-503034)

Boceprevir is a protease inhibitor used as a treatment for hepatitis C genotype 1.*Available package size: 5,10,25,50mg

A11335 Balapiravir (R1626)

A11336 BMS-790052 2HCl

A11343 Ciluprevir (BILN 2061)

A11519 PSI-6130

A11529 PSI-7977

A11530 PSI-6206

A11583 Tegobuvir (GS-9190)

A12357 BMS-790052

A12374 VCH-916

A13105 Setrobuvir (ANA-598)

A13118 Celgosivir

A13155 Ledipasvir (GS 5885)

Ledipasvir is an inhibitor of the hepatitis C virus HCV NS5A protein.*Available package size: 5,10,25,50mg

HIV ProteaseA10096 Atazanavir sulfate (BMS-232632-05)

A10097 Atazanavir

A10512 Lamivudine

A10537 Lopinavir (ABT-378)

Proteases Proteases

Lopinavir is an inhibitor of the HIV protease.*Available package size: 10,100,200mg

A10799 Ritonavir

Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.*Available package size: 10,25,50,100mg

A11378 Saquinavir

A11853 Darunavir Ethanolate (Prezista)

A11871 Indinavir sulfate

A11985 Amprenavir

Amprenavir is an human immunodeficiency virus (HIV) protease inhibitor with IC50 of 14.6 ± 12.5 ng/ml for wild-type HIV isolates*Available package size: 5,10,25,50mg

A12583 Fosamprenavir

A13156 GSK2838232A

Heat Shock Proteins (HSP)

A10010 17-AAG (KOS953)

A10011 17-DMAG HCl (Alvespimycin)

A10143 BIIB021

BIIB021 is an oral fully synthetic Hsp90 inhibitor that selectively and potently inhibits the molecular chaperone Hsp90 thereby inhibiting the proper assembly of multiple oncogenic proteins involved in tumor growth and survival.*Available package size: 5,10,50,100mg

A10178 Capsaicin

A10343 Elesclomol

A10659 AUY922 (NVP-AUY922)

AUY922 (NVP-AUY922) is highly potent and oral inhibitor of Hsp90 with IC50=21 nM in Hsp90 FP binding assay and inhibits proliferation of various human cancer cell lines in vitro, with GI50 average 9 nM.*Available package size: 5,10,25,100mg

A10660 NVP-BEP800

A11025 Geldanamycin

A11062 AT13387

A11074 PF-04929113 (SNX-5422)

A11130 PU-H71

A11131 MPC-3100

A11189 SNX-2112

A11195 KW-2478

KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.*Available package size: 5,10,50,100mg

A11251 XL-888

A11269 IPI-504 (Retaspimycin hydrochloride)

A11272 IPI-493

IPI-493 is a potent and orally bioavailable HSP90 inhibitor with Ki of 21 nM.*Available package size: 1,2,5,10mg


33 34

Aminopeptidase

A10208 CHR2797 (Tosedostat)

Integrase

A10042 Fluorouracil (Adrucil)

A10156 BMS-707035

A10347 Elvitegravir (GS-9137)

Dipeptidyl Peptidase IV (DPP-4)A10430 Glimepiride

A10848 Sitagliptin phosphate monohydrate

A11109 Saxagliptin (BMS-477118)

A11224 Linagliptin (BI-1356)

A11768 Radicicol

A12388 MKT 077

A12648 CUDC-305 (DEBIO-0932 )

A12850 HSP-990

A13351 VER 155008

A13817 VER-50589

Elvitegravir (GS-9137) is a potent inhibitor of the strand-transfer step of integration mediated by human immunodeficiency virus type 1 (HIV-1) integrase.*Available package size: 10,50,100mg

A10775 Raltegravir (MK-0518)

Raltegravir (MK-0518) targets integrase, an HIV enzyme that integrates the viral genetic material into human chromosomes, a critical step in the pathogenesis of HIV.*Available package size: 5,10,50,100mg

A11068 S/GSK1349572

A11135 MK-2048

Angiotensin-Converting Enzyme (ACE)

A10670 Olmesartan (RNH6270, CS-088)

A10710 Perindopril Erbumine (Aceon)

A11317 Moxonidine

A11615 Olmesartan medoxomil

A11738 Captopril

A11748 Fosinopril sodium

A11867 Imidapril (Tanatril)

A11876 Lisinopril (Zestril)

A12769 Zofenopril calcium

Matrix Metalloprotease

Other Proteases

A11345 CTS-1027

A12985 Batimastat (BB-94)

A11764 Camostat mesylate

A12928 MI 2

MMP CathepsinA12826 Marimastat

A12848 4-epi-Chlortetracycline Hydrochloride

A13072 NSC 405020

A12020 Balicatib

A13256 CA-074

ThrombinA10138 BIBR 953 (Dabigatran, Pradaxa)

A12528 Vildagliptin

A13311 Alogliptin Benzoate

A13312 Trelagliptin Succinate (SYR-472)

Linagliptin is a DPP-4 inhibitor, an enzyme that degrades the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).*Available package size: 5,10,50,100mg

A11331 BCX 1470

A11517 Otamixaban (FXV 673)

BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro.*Available package size: 5,10,25,50mg

A11325 BCX 1470 methanesulfonate

BIBR 953 (Dabigatran, Pradaxa) has shown antithrombotic efficacy in animal models of thrombosis, with a rapid onset of action and predictable pharmacodynamic response.*Available package size: 5,10,50,100mg

Proteases Proteases

Epigenetics

Stem Cells

Stem Cell ProliferationA12922 ID 8

Stem Cell Differentiation

A12926 Kartogenin

BromodomainA11440 GSK 525762A (I-BET-762)

A11783 GSK 1210151A (I-BET151)

(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor.*Available package size: 5,10,25,50mg

GSK1210151A is a novel selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4.*Available package size: 5,10,25,50mg

A12545 PFI-1

A12729 (+)-JQ1

Histone demethylases

A12918 GSK J1

A13246 OG-L002

A13358 Tranylcypromine hydrochloride

GSK J1 is a potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX.*Available package size: 10,25,50,100mg

A12948 UNC1215

A13068 CPI-203

A13163 Bromosporine

A13165 I-CBP112

A13227 SGC-CBP30

A13717 UNC 669

A13749 MS436

A13890 OTX015

A14015 GSK2801


35 36

GSK-3 / Wnt / Hedgehogγ-Secretase

A10157 BMS-708163

A10288 DAPT (GSI-IX)

Hedgehog

A10249 Cyclopamine

A10258 GDC-0449 (Vismodegib)

A11048 LY2940680

DAPT (GSI-IX) is an inhibitor of γ-secretase that causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures with IC50 values of 115 and 200 nM for total Aβ and Aβ42 respectively.*Available package size: 5,10,50,100mg

A10802 RO4929097

A10836 Semagacestat (LY450139)

A11174 YO-01027

YO-01027 is a dipeptidic γ-secretase inhibitor, an antiAlzheimer agent.*Available package size: 5,10,25,50mg

A11176 LY-411575

LY-411575 is a selective, cell permeable, small molecule gamma secretase inhibitor.*Available package size: 5,10,50,100mg

A11194 MK-0752

A11337 BMS 433796

A11393 E 2012

A11776 LY2811376

A12433 Flurizan

A12444 BMS 299897

A13815 FLI-06

GDC-0449 (Vismodegib) is a more potent novel and specific synthetic oral hedgehog pathway inhibitor with an IC50 of 3 nM.*Available package size: 25,50,200mg

A11351 TAK-441

A11442 GANT 58

A12418 HhAntag

A12920 Hh-Ag1.5

A13095 SANT-1

A13252 GANT61

WntA10994 XAV 939

β-catenin

A12737 IWR-1-endo

A13795 FH535

GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.*Available package size: 10,25,50,100mg

XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively). *Available package size: 10,25,50,100mg

A12362 KY02111

A12707 IWP-2

A12737 IWR-1-endo

A12816 LGK-974

LGK974 is a highly potent, selective and orally bioavailable Porcupine inhibitor (Wnt signaling antagonist) with an IC50 <1 nM in the Wnt signaling reporter assay and Porcupine binding assay.*Available package size: 5,10,25,50mg

GSK-3A10199 CHIR-99021

CHIR99021 is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively.*Available package size: 2,5,25,100mg

A10471 Indirubin

A10825 SB 216763

A11061 SB 415286

GSK-3 / Wnt / Hedgehog

GSK-3 / Wnt / Hedgehog

SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM. *Available package size: 10,25,50,100mg

A11085 CHIR-98014

CHIR-98014 is a very potent, selective, cell-permeable reversible inhibitor of GSK-3.*Available package size: 5,10,50,100mg

A11143 SB-705498

A11223 TWS119

TWS119 is a 4,6 disubstituted pyrrolopyrimidine that potently inhibits GSK3β with an IC50 value of 30 nM.1 At 400 nM.*Available package size: 5,10,25,50mg

A11592 Tideglusib

A11941 TDZD-8

TDZD-8 protects the brain against I/R injury by inhibiting GSK-3beta activity.*Available package size: 5,10,25,50mg

A12741 LY2090314

A12819 AZD1080

A13060 AZD2858

A13728 AR-A 014418

Smoothened

A11480 Purmorphamine

A12774 LDE225 Diphosphate

LDE225 is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity.*Available package size: 5,10,25,50mg

A12775 PF-5274857

A13204 BMS-833923 (XL-139)

BMS-833923 (or XL-139) is an orally bioavailable small-molecule SMO (Smoothened) inhibitor with potential antineoplastic activity.*Available package size: 5,10,25,50mg

A13881 PF-04449913

IWP-2 is an inactivator of Porcn function and inhibitor of Wnt production, and blocks beta-catenin accumulation. Wnt/b-catenin ('canonical') pathway maintains transcriptional programs that enable stem cells to remain multipotent.*Available package size: 5,10,25,100mg

A12951 Wnt-C59

A13978 IWP-L6


37 38

TransportersATPase

A10086 Artemisinin

A10213 Ciclopirox

A12024 Bufotalin

A12032 Cinobufagin

A12726 Dynasore

A12755 Ouabain

A13283 Rostafuroxin (PST-2238)

A13647 (-)-Blebbistcitin

A10669 Oligomycin A

A10672 Omeprazole

A11156 Brefeldin A

A11408 PF 3716556

A11696 Pantoprazole (Protonix)

Bufalin is a cardiotonic steroid originally isolated from the Chinese toad venom.*Available package size: 10,25,50,100mg

Ciclopirox is currently being investigated as an alternative treatment to ketoconazole for seborrhoeic dermatitis as it suppresses growth of the yeast Malassezia furfur.It acts by inhibiting the membrane transfer system by interrupting the Na+ K+ ATPase.*Available package size: 10,25,50,100mg

Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion.*Available package size: 100,500mg

A11933 KB-R7943 mesylate

A11961 Bafilomycin A1

A12022 Bufalin

A12023 Resibufogenin

Rostafuroxin (PST-2238) is an ouabain-inhibitor counteracting specific forms of hypertension.*Available package size: 5,10,25,50mg

Multidrug Transporters

A10549 LY335979

A11080 PSC-833

A12324 Elacridar

Elacridar is a prototypical BCRP inhibitor which inhibits the Bcrp1-mediated transport.*Available package size: 5,10,25,50mg

Neurotransmitter Transporters

AMPA receptor

P-gp

CRM1

A10222 Citalopram Hydrobromide

A10319 Dipyridamole

A11919 Reboxetine mesylate

A11960 LY 2183240

A13099 UCPH 101

A12349 Ampalex (CX-516)

A12424 LY404187

A12425 LY450108

A13109 NBQX

A13882 DNQX

A14010 IEM 1754 Dihydrobromide

A11584 Tariquidar (XR9576)

A12004 Cynarin

A12363 Selamectin

A12582 KPT-330

A12975 KPT185

KPT185 is a selective CRM1 inhibitor. KPT-185 significantly inhibits leukemia cell proliferation with IC50 ranging from 100 nM to 500 nM, and induces cell-cycle arrest and apoptosis of AML cell lines and primary AML blasts.*Available package size: 10,25,50,100mg

Monocarboxylate transporters (MCT)

A10155 EGT1442

A10285 Dapagliflozin (BMS512148)

A11293 AR-C155858

A13372 CHC

AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10.*Available package size: 5,10,25mg

A11100 Canagliflozin

A12440 Empagliflozin

A12680 LX-4211

A12690 Tofogliflozin

Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.*Available package size: 5,10,50,100mg

Sodium-dependent Glucose Cotransporter (SGLT)

Transporters Transporters

Ion ChannelsCalcium ChannelsA10068 Amlodipine

A10069 Amlodipine besylate (Norvasc)

A10215 Cilnidipine

A10219 AMG-073 HCl (Cinacalcet HCl)

AMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium.*Available package size: 10,50,100mg

A10309 Diethylstilbestrol

A10311 Diltiazem HCl

A10487 Isradipine

A10553 Manidipine (Manyper)

A10554 Manidipine dihydrochloride

A10643 Nifedipine

A10645 Nimodipine

A10921 Tetrandrine (Fanchinine)

A11140 NPS-2143 (SB-262470)

A11206 CK-1827452 (Omecamtiv mecarbil)

CK-1827452 is a selective cardiac specific myosin activator.*Available package size: 5,10,50,100mg

A11219 Azelnidipine

A11314 AMG 073 (Cinacalcet)

A11729 Lacidipine

A11730 Benidipine hydrochloride

A11731 Nilvadipine (ARC029)

A11746 Clevidipine

A12684 Pinaverium Bromide

A13989 BAPTA tetrapotassium

A14023 BAPTA/AM

BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures.*Available package size: 25,50,100mg

Ligand-gated Ion Channels

A10006 (-)-Huperzine A

A10414 Gabapentin Hydrochloride

A10444 GYKI-52466 dihydrochloride

A10490 Ivermectin

A10748 Prasugrel (Effient)

A10966 Varenicline

A11107 GW791343 HCl


39 40

Sodium ChannelsA10064 Amiloride hydrochloride

A10510 Lacosamide

A10530 Lidocaine (Alphacaine)

A10721 Phenytoin (Lepitoin)

A10722 Phenytoin sodium (Dilantin)

A10795 Riluzole (Rilutek)

A11102 PF-04971729

A11234 A 803467

Potassium ChannelsA10433 Glyburide

A10593 Minoxidil (U-10858)

A10629 Nateglinide (Starlix)

A10641 Nicorandil

A10783 Repaglinide

A11239 TAK-438

A11233 PNU 282987

PNU 282987 is a drug that acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors.*Available package size: 10,25,50,100mg

A11290 A-867744

A11701 Ondansetron (Zofran)

A11708 Memantine hydrochloride

A11862 Felbamate

A11873 Lamotrigine

A11947 TCN 201

A12426 SDZ 220-581

A12681 Methyllycaconitine citrate

A12751 NMDA

A13784 Bretazenil

A 803467 is a selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively).*Available package size: 10,25,50,100mg

A11602 Vinpocetine

A11715 Proparacaine HCl

A11728 Amiloride hydrochloride dihydrate

A11750 Ibutilide fumarate

A13760 QX 314 chloride

TAK-438 is a novel potassium-competitive acid blocker.*Available package size: 2,5,10,25mg

QX 314 chloride is a membrane impermeable quaternary derivative of lidocaine, a voltage-activated Na+ channel blocker.*Available package size: 50,100,250mg

Chloride Channels

Cystic Fibrosis Transmembrane Regulator (CFTR)

A10985 VX-770 (Ivacaftor)

A13339 Talniflumate

A10758 PTC124 (Ataluren)

A11884 Mitiglinide calcium

A11922 Retigabine (Ezogabine)

A11934 NS 309

A12783 TRAM-34

A12857 E-4031 dihydrochloride

PTC124 also known as Ataluren is CFTR-G542X nonsense allele inhibitor.*Available package size: 10,25,50,100mg

A10986 VX-809

A12519 VX-661

A13000 PPQ-102

A13511 IOWH032

A13723 CFTR-Inhibitor-IINMDA ReceptorsA13729 MDL 29951Transient Receptor Potential Channels

A12353 A 967079

A 967079 is a selective TRPA1 channel blocker (IC50 values are 67 and 289 nM at human and rat TRPA1 receptors respectively).*Available package size: 10,25,50,100mg

A12932 Optovin

A13278 HC-030031

A13333 Flufenamic acid

A13560 Icilin

A11521 PAP-1 (5-(4-Phenoxybutoxy)psoralen)

PAP-1 is a selective inhibitor of Kv1.3, voltage-gated potassium channel. PAP-1 (EC50=2 nM) potently inhibits human T effector memory cell proliferation and delayed hypersensitivity.*Available package size: 5,10,25,50mg

VX-770 (Ivacaftor) is known as a CFTR potentiator.*Available package size: 5,10,50,100mg

A10985 VX-770 (Ivacaftor)

MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo.*Available package size: 5,10,25,50mg

AMPK / Insulin ReceptorAMPK

A10028 Acadesine (Aicar,NSC 105823)

A10717 Phenformin hydrochloride

A11071 A-769662

A-769662 is a new activator of AMP-activated protein kinase (AMPK).*Available package size: 5,10,50,100mg

A11970 BML-275

BML-275 is a cell-permeable pyrazolopyrimidine compound shown to be an AMP-activated protein kinase (AMPK) and fatty acid synthase inhibitor.*Available package size: 5,10,50mg

ATM / ATRATM

A10506 KU-55933

KU-55933 is an ATM inhibitor by suppressing cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.*Available package size: 5,10,50,100mg

A10507 KU-60019

A11086 CP-466722

A11605 VE-821

A13191 CGK 733

A13205 AZ-20

ATRA13289 VE-822

A13328 ETP-46464

VE-822 is an potent ATR inhibitor.*Available package size: 5,10,25,50mg

Ion Channels Ion Channels


41 42

7-TM Receptors5-HT Receptors

Adrenergic ReceptorsA10017 5-hydroxytryptophan (5-HTP)

A10048 Agomelatine

A10091 Asenapine maleate

A10231 Clomipramine hydrochloride

A10287 Dapoxetine hydrochloride

A10437 Granisetron Hydrochloride

A10497 Ketanserin (Vulketan Gel)

A10588 Mianserin hydrochloride

A10607 Mosapride citrate

A10624 Naratriptan

A10667 Olanzapine (LY170053)

A10674 Ondansetron HCl (GR 38032F)

A10691 Paliperidone

A10759 Puerarin (Kakonein)

A10797 Risperidone (Risperdal)

A10931 Tianeptine sodium

A11106 LY310762

A11116 Vilazodone

A11165 RS-127445

A11178 BRL-15572

A11182 WAY-100635

A11208 BMY 7378

A11226 Tropisetron (ICS 205930)

A11310 Alosetron

A11418 Eletriptan hydrobromide

A11702 Mirtazapine

A11703 Trazodone hydrochloride

A11704 Urapidil hydrochloride

A11705 Duloxetine

A11717 Duloxetine HCl

A11743 Tegaserod maleate

A11771 Prucalopride

A11799 Almotriptan malate (Axert)

A11801 Aripiprazole (Abilify)

A11925 SB269970 HCl

A12378 Lorcaserin

A12521 Lu AE58054

A12598 lorcaserin hydrochloride (APD-356)

A12602 Vortioxetine hydrobromide

A13075 Eletriptan

A13092 NAD 299 hydrochloride (Robalzotan)

A13267 PRX-08066

A13293 Tandospirone

A13757 PU 02

A13762 N-Desmethylclozapine

A13766 SDZ 205-557 HCl

A13767 Tropanserin

A13833 RU 24969 hemisuccinate

A10052 Alfuzosin HCl

A10149 Bisoprolol fumarate

A10232 Clonidine hydrochloride

A10296 Dehydroepiandrosterone

A10298 Detomidine hydrochloride

A10325 Dobutamine hydrochloride

A10334 Doxazosin mesylate

A10484 Isoprenaline HCl

A10555 Maprotiline hydrochloride

A10618 Naftopidil (Flivas)

A10619 Naftopidil Dihydrochloride

A10630 Nebivolol HCl

A10686 Oxymetazoline hydrochloride

A10719 Phenoxybenzamine hydrochloride

A10794 Rilmenidine

A10819 Salbutamol sulfate (Albuterol)

A10882 Synephrine (Oxedrine)

A11229 Metroprolol succinate

A11666 Phenylephrine hydrochloride

A11668 DL-Adrenaline

A11713 Metoprolol tartrate

A11721 Betaxolol

A11732 Formoterol hemifumarate

A11733 Betaxolol hydrochloride

A11734 Phentolamine mesilate

A11740 Terazosin hydrochloride

A11788 Salmeterol

A11807 Adrenalone HCl

A11843 Carvedilol

A11868 Ivabradine HCl (Procoralan)

A11905 Procaterol HCl

A11914 Prazosin HCl

A11923 ARN-509

A12657 Tamsulosin

A12795 Arformoterol tartrate

A12844 Formoterol

A13080 Tetrahydrozoline Hydrochloride

A13225 ICI 118,551 hydrochloride

A13406 Bisoprolol

A13413 Medetomidine hydrochloride

A13419 Octopamine hydrochloride

A13422 Pindolol

A13738 Nebivolol

Acetylcholine Muscarinic Receptors

Histamine Receptors

A10032 Acetylcysteine

A10098 Atropine

A10147 Biperiden hydrochloride

A10180 Bethanechol chloride

A10386 Fesoterodine fumarate (Toviaz)

A10416 Galanthamine hydrobromide

A10417 Gallamine triethiodide

A10476 Ipratropium bromide

A10480 Irsogladine

A10579 Methscopolamine bromide

A10635 Neostigmine bromide (Prostigmin)

A10684 Oxybutynin

A10803 Rocuronium bromide

A10808 SVT-40776 (Tarafenacin)

A10937 Tolterodine tartrate (Detrol LA)

A11166 5-hydroxymethyl tolterodine

A11203 PNU-120596

A11215 Solifenacin succinate

A11706 Tropicamide

A11712 Orphenadrine citrate

A11719 Rivastigmine tartrate

A11975 Methoctramine hydrate

A11987 Darifenacin

A13071 Arecoline

A10117 Azelastine hydrochloride (Allergodil)

A10195 Cetirizine Dihydrochloride

A10205 Chlorpheniramine maleate

A10218 Cimetidine

A10226 Clemastine fumarate

A10538 Loratadine

A10671 Olopatadine hydrochloride

A11117 Ciproxifan maleate

A11222 Rupatadine

A11340 Bepotastine Besilate

A11360 Ciproxifan

A11699 Brompheniramine

A11709 Cyproheptadine hydrochloride

A11724 Mizolastine

A11859 Fexofenadine HCl

A11921 Roxatidine acetate hydrochloride

A12356 Rupatadine Fumarate

A12661 Bilastine

A12713 JNJ7777120

A12845 Bepotastine

A13086 Metiamide

Dopamine Receptors

A10061 Amfebutamone (Bupropion)

A10067 Amisulpride

A10125 Benserazide hydrochloride (Serazide)

A10236 Clozapine

A10329 Domperidone

A10331 Dopamine hydrochloride

A10446 Haloperidol (Haldol)

A10747 Pramipexole 2HCl monohyrate

A10956 U 95666E

A11118 Rotigotine hydrochloride

A11119 Thioridazine hydrochloride

A11341 B-HT 920 2HCl

A11553 Rotigotine

A11559 SB-277011

A11720 Fenoldopam

A11824 Blonanserin

A11915 Ropinirole

A11916 Ropinirole HCl

A11937 GBR-12935 dihydrochloride

A11998 Rotundine

A12415 BP897

A12536 Pramipexole dihydrochloride

A12991 GR 103691

A13087 Naxagolide

A13694 L-741626

A13844 Cabergoline

7-TM Receptors 7-TM Receptors

Opioid ReceptorsA10350 Enalapril maleate

A10561 MCOPPB trihydrochloride

A11072 ADL5859 HCl

A11076 JTC-801

A11210 BRL 52537 hydrochloride

A11322 BAN ORL 24

A11718 Trimebutine

A13843 Nalmefene hydrochloride

GABA Receptors

A10121 Baicalin

A10397 Flumazenil

A10412 Furosemide

A10413 Gabapentin

A10754 Primidone (Mysoline)

A10849 SKF 89976A hydrochloride

A12590 (+)-Bicuculline

A12689 Phenazepam

A13696 2-Hydroxysaclofen

A13726 AWD 131-138

Purinergic (P2Y) Receptors


43 44A10233 Clopidogrel (Plavix)

A11238 Ticagrelor (AZD6140)

A11486 MRS 2578

Metabotropic glutamate receptors (mGluR)A10544 LY2140023 (LY404039)

A11126 BINA

A11181 ADX-47273

A11754 VU 0357121

A11968 CTEP

A12467 VU 0361737

A12589 MPEP hydrochloride

A12664 VU 0364439

A12705 PHCCC

A13123 LY 379268

A13236 MPEP HCl

A13758 SIB 1757

A13759 SIB 1893

Angiotensin ReceptorsA10891 Tasosartan

A10905 Telmisartan

A11121 Eprosartan

A11775 Azilsartan (TAK-536)

A13747 Eprosartan mesylate

Melatonin ReceptorsA10564 Melatonin

Peptide ReceptorsA10598 MK 3207 hydrochloride

A11255 MK-0974 (Telcagepant)

A11567 SB-408124

A11594 Tolvaptan

A11820 Prostaglandin E1 (PGE1)

A11979 YIL 781

A12158 BIIE 0246

A12350 Ozarelix

A12351 Desmopressin

A12646 Melanotan II

A12790 Parathyroid Hormone 1-34, Human

A12860 THIQ

A13102 BMS-927711

Smoothened Receptors

A10520 LDE225 (NVP-LDE225)

Chemokine Receptors (CCR5)

A10556 Maraviroc (UK-427857)

A10971 Vicriviroc Malate

A11097 SRT3109

A11104 INCB 3284 dimesylate

A11127 MK-0812

A11315 AMD 070

A11555 SCH-527123

A11577 SRT3190

A11953 AMD 3465 Hexahydrobromide

A12383 Reparixin

A12588 WZ811

A12596 MSX-122

A13074 AMD3100 (Plerixafor)

G Protein

A11228 QS 11

A11373 CCG-63802

A12912 CASIN

A13886 EHT 1864

Platelet-Activating Factor (PAF) ReceptorsA10429 Ginkgolide B

A11739 Ginkgolide A

Endothelin Receptors

A11006 Zibotentan (ZD4054)

A11091 Bosentan

A11291 Ambrisentan (BSF 208075)

A11564 Sitaxsentan sodium (TBC-11251)

P2X ReceptorA11107 GW791343 HCl

A11316 A 740003

A11473 KN-62

A11690 Ticlopidine hydrochloride

A11972 NF 279

A12412 A-317491 sodium salt hydrate

LPA ReceptorA10501 Ki16425

A11966 Ki16198

Prostanoid ReceptorsA10688 Ozagrel(OKY-046)

A11483 Laropiprant (MK0524)

A11742 Ozagrel hydrochloride

A13498 Cloprostenol (sodium salt)

A13751 BAY-u 3405

Adenosine Receptors

A10040 Adenosine

A10066 Aminophylline

A10339 Dyphylline

A11451 Istradefylline (KW-6002)

A11560 SYN-115

A11619 CGS 21680 hydrochloride

A12695 SCH 442416

A12846 Tamsulosin hydrochloride

A13745 CVT 6883

Cannabinoid Receptors

A11253 GW842166X

A11513 Org 27569

A11547 Rimonabant (SR141716)

A11780 JWH 133

A11932 WIN 55,212-2 mesylate

A11938 BML-190

A11939 MDA 19

A11942 CP 945598 hydrochloride

A12849 AB-FUBINACA

A12914 AM251

Neurotensin ReceptorsA11770 SR 48692

Leukotriene receptorA11607 MK-0679 (Verlukast)

A11908 Pranlukast (ONO 1078)

A13090 LY 255283

Orexin ReceptorsA11500 MK-4305 (Suvorexant)

A12651 SB-649868

A12786 SB 334867

A13439 TCS 1102

Somatostatin ReceptorsA12782 Octreotide

NK1 ReceptorsA13103 GW679769 (Casopitant)

A13104 Ibodutant (MEN 15596)

Protease-Activated Receptors (PAR)A13495 ML 161

Endocrinology / Hormones

7-TM Receptors 7-TM Receptors

Pregnane X ReceptorsA10791 Rifampin

A11700 Meclizine dihydrochloride

A11909 Pregnenolone

Estrogen ReceptorsA10230 Clomifene citrate

A10308 Dienogest

A10336 Drospirenone

A10375 Evista (Raloxifene Hydrochloride)

A10410 Fulvestrant (Faslodex)

A10439 GSK1292263

A10451 Hexestrol

A10550 LY500307

A10591 Mifepristone (Mifeprex)

A11018 TAK-875

TAK-875 is a potent, selective, and orally bioavailable GPR40 agonist.*Available package size: 5,10,50,100mg

A11665 Bazedoxifene acetate

A11667 Ethisterone

A11965 GW9508

A12083 Liquiritigenin

A13299 XCT 790

A13740 Zearalenone

Progesterone ReceptorsA10336 Drospirenone

A10529 Levonorgestrel

A10885 Tamoxifen Citrate


45 46

Renin-angiotensin-aldosterone system (RAAS)A10123 Benazepril hydrochloride

A10175 Candesartan (Atacand)

Candesartan is an angiotensin receptor blocker (also called an angiotensin-II receptor antagonist or an AIIRA).*Available package size: 5,10,50,100mg

A10176 Candesartan cilexetil (Atacand)

A10351 Enalaprilat dihydrate

A10810 Rosuvastatin calcium (Crestor)

A11122 Rosuvastatin

A11123 Aliskiren hemifumarate

A11184 Clinofibrate

A11616 Aliskiren (CGP 60536)

A11736 Quinapril hydrochloride

A11745 Moexipril hydrochloride

A11747 Cilazapril monohydrate

A11749 Temocapril

A13201 PD 123319 ditrifluoroacetate

Androgen ReceptorsA10008 (R)-Bicalutamide

A10009 17 alpha-propionate

A10076 Andarine (GTX-007)

A10142 Bicalutamide (Casodex)

A10253 Ostarine (MK-2866)

PPARA10424 Gemfibrozil (Lopid)

A10807 Rosiglitazone (BRL-49653)

PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin AT2 receptor antagonist. IC50 values are 34 and 210 nM in rat adrenal tissue and brain respectively.*Available package size: 10,25,50,100mg

Ostarine is an androgen receptor modulator (SARM).*Available package size: 5,10,50,200mg

A10562 MDV3100

MDV3100 is androgen-receptor inhibitor. Highly recommended inhibitor in AR research.*Available package size: 5,10,25,50mg

A12396 AZD3514

A12805 BMS564929

A13398 Bopindolol malonate

A13407 Clenbuterol hydrochloride

Rosiglitazone works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin.*Available package size: 25,50,100,200mg

A10809 Rosiglitazone maleate

A11137 Cetaben

A11437 GW 501516

A11727 Ciprofibrate

A11981 Troglitazone

A11982 GW 7647

A11983 L-165,041

A11984 GW 9662

A12360 pirinixic acid (WY 14643)

A12391 GSK-3787

A12392 GSK 0660

A12413 GW6471

Liver X receptors (LXRs)

A11141 GW4064

A11186 WAY-362450

A11204 GW3965 HCl


GW3965 HCl is a selective and orally active liver X receptor (LXR) full agonist.*Available package size: 5,10,50,100mg

A12166 Mogroside II A2

A12652 T0901317

A12865 Cerpegin

AromataseA10075 Anastrozole

A10378 Exemestane

A10523 Letrozole

Retinoic Acid ReceptorsA11792 AM 580

A11793 CD 437

A12430 Palovarotene

A13113 Talarozole

Letrozole is an Aromatase inhibitor. CGS 20267 is a new non-steroidal compound which potently inhibits aromatase in vitro (IC50 of 11.5 nM) and in vivo (ED50 of 1–3 μg/kg p.o.)*Available package size: 10,50,100mg

A10563 Megestrol Acetate

A11088 Fadrozole


Glucocorticoid receptors

A10457 Hydrocortisone(Cortisol)

A11860 Fluticasone propionate

Vitamin D Receptors

A11413 Ercalcidiol

GnRH receptorA12375 NBI-42902

A12376 SR 144528

GPR

A13186 AZD1981

AZD1981, as a potent antagonist in a disease relevant cell system, inhibits DK-PGD2-induced CD11b expression in human eosinophils with IC50 of 10 nM.*Available package size: 5,10,25mg

A12613 Abarelix Acetate

A12840 Degarelix acetate

A12862 Ganirelix

SR 144528 displays a Ki value of 0.6 nM for rat spleen and human recombinant CB2 receptors and a Ki value of 400 nM for rat brain and human recombinant CB1 receptors.*Available package size: 5,10,25,50mg

TransferasesGlucocorticoid receptorsA11199 A 922500

A 922500 is a diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50 values are 7 and 24 nM at human and mouse DGAT-1 respectively).*Available package size: 5,10,50,100mg

A11415 Etomoxir

Etomoxir is an inhibitor of carnitine palmitoyltransferase A (CPT1), which is required for the oxidation of long-chain acyl CoA esters. Also a strong inhibitor of mitochondrial CPT1 and a candidate as an anti-diabetic drug.*Available package size: 5,10,25,50mg

PhosphorylasesA11173 CP-91149


47 48

MethyltransferasesA11763 BIX 01294

A13110 Opicapone (BIA 9-1067)

Protein PrenyltransferasesA12368 FTI 277

A14020 LB42708

FPTaseA12328 Lonafarnib (SCH66336)

BIX 01294 is a G9a- l ike protein and G9a histone lys ine methyltransferase inhibitor.*Available package size: 10,25,50,100mg

Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.*Available package size: 5,10,25,50mg

Histone Methyltransferase

A11377 DZNep

3 Deazaneplanocin A (DZNep) is a cyclopentenyl analog of 3-deazaadenosine, originally synthesized as an inhibitor of S-adenosyl-L-homocysteine hydrolase.*Available package size: 1,2,5,10mg

A12439 EPZ005687

EPZ005687 is a potent inhibitor of EZH2 (K(i) of 24 nM).*Available package size: 5,10,25,50mg

A12712 EPZ-6438

A12735 EPZ-5676

A12812 Chaetocin

A12941 SGC 0946

EPZ-5676 is a small molecule inhibitor of histone methyltransferase with potential antineoplastic activity.*Available package size: 5,10,25,50mg

SGC 0946 is a potent DOT1L methyltransferase inhibitor that blocks H3K79 methylation in A431 cells and MCF10A cells.*Available package size: 5,10,25,50mg

Histone Acetyltransferases

DNA Methyltransferases

A12814 Garcinol

A12815 C646

A13378 NU 9056

A12785 Lomeguatrib

A12983 EPZ004777

A13114 GSK343

A13194 UNC0646

A13200 UNC0321

A13690 UNC 0638

UNC 0638 is a selective inhibitor of G9a and GLP histone lysine methyltransferases.*Available package size: 10,25,50mg

Ubiquitinactivating enzyme E1

p97

DUB

E3 ubiquitin ligase

A13254 PYR-41

A13253 SMER-3

A12715 LDN-57444

A13190 PR-619

A12377 NMS-873

A12736 DBeq

NMS-873 is a potent and specific small molecule allosteric inhibitor of the ATPase VCP/p97 (IC50 ~0.03 uM), identified by a high-throughput screening.*Available package size: 5,10,25,50mg

P005091 is a selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2 uM).*Available package size: 10,25,50mg

PYR-41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM).*Available package size: 10,25,50,100mg

A13209 IU1

A13277 P005091

PR-619 is a cell-permeable, reversible, and broad-spectrum inhibitor of the deubiquitinylating enzymes (DUBs).*Available package size: 5,10,25,50mg

Transferases Ubiquitin

OthersOther inhibitorsA10005 (-)-Epigallocatechin gallate

A10013 3-Indolebutyric acid

A10014 4-Demethylepipodophyllotoxin

A10015 4-Methylumbelliferone (4-MU)

A10016 5-Aminolevulinic acid hydrochloride

A10018 7-Aminocephalosporanic acid

A10023 ABT-492

A10029 Acarbose

A10031 Acetanilide

A10033 Acipimox

A10034 Acitazanolast

A10035 Acitretin

A10038 Adapalene

A10044 Aesculin (Esculin)

A10051 Alfacalcidol

A10054 Alizarin

A10055 Allopurinol

A10056 Allopurinol sodium

A10057 Aloe-emodin

A10058 Aloin (Barbaloin)

A10059 Altretamine

A10065 Aminocaproic acid (Amicar)

A10070 Ammonium Glycyrrhizinate (AMGZ)

A10072 Amorolfine Hydrochloride


49 50

A10169 Busulfan (Myleran, Busulfex)

A10170 Butylscopolamine BR

A10171 Caffeic acid

A10173 Calcitriol (Rocaltrol)

A10181 Carbidopa

A10186 Cefaclor

A10187 Cefdinir

A10189 Cefoselis sulfate

A10190 Cefprozil hydrate (Cefzil)

A10191 Ceftiofur hydrochloride

A10192 Celastrol

A10197 Chenodeoxycholic acid

A10201 Chlormezanone (Trancopal)

A10202 Chlorogenic acid

A10203 Chlorothiazide

A10207 Chlorprothixene

A10209 Chrysin

A10214 Cidofovir (Vistide)

A10220 Cinchonidine

A10225 Clarithromycin

A10227 Clindamycin hydrochloride

A10229 Clofibrate

A10235 Cloxacillin sodium

A10237 Coenzyme Q10 (CoQ10)

A10239 Cortisone acetate

A10243 Crotamiton

A10245 Crystal violet

A10247 Curcumol

A10252 Dihydromyricetin (Ampeloptin)

A10260 Cyclosporin A

A10261 Bryostatin 1

A10262 Cyclovirobuxin D (Bebuxine)

A10265 Cytarabine

A10266 Cytisine (Baphitoxine, Sophorine)

A10282 Daidzein

A10283 Daidzin

A10289 Daptomycin

A10291 D-Cycloserine

A10294 Deflazacort

A10297 Desonide

A10299 Dexamethasone

A10300 Dexrazoxane Hydrochloride

A10302 D-glutamine

A10305 Diclofensine

A10306 Didanosine

A10307 Dienestrol

A10310 Dihydroartemisinin

A10313 Dimesna (BNP7787)

A10314 Dioscin (Collettiside III)

A10315 Diosgenin

A10316 Diosmetin

A10317 Diosmin

A10318 Diphenhydramine hcl

A10321 Divalproex sodium

A10322 DL-Carnitine hydrochloride

A10323 D-Mannitol

A10327 Docosanol

A10328 Dofetilide

A10332 Doripenem Hydrate

A10333 Dorzolamide HCL

A10335 Doxercalciferol

A10341 Ecdysone

A10342 Econazole nitrate

A10348 Emodin

A10353 Glycyrrhetinic acid (Enoxolone)

A10361 Ergosterol

A10376 Evodiamine (Isoevodiamine)

A10379 Ezetimibe (Zetia)

A10388 Fisetin (Fustel)

A10389 FK-506

A10394 Flucytosine

A10406 Formononetin (Formononetol)

A10407 Tegafur

A10409 Fudosteine

A10411 Fumalic acid (Ferulic acid)

A10415 Gadodiamide (Omniscan)

A10418 Gastrodin (Gastrodine)

A10423 Gemcitabine HCl (Gemzar)

A10426 Genistin (Genistoside)

A10427 Gentamycin sulfate (Gentacycol)

A10428 Gestodene

A10432 L-Glutamine

A10434 Glycyrrhizic acid

A10435 Gossypol

A10436 Gramine

A10443 Guaifenesin (Guaiphenesin)

A10445 Gynostemma Extract

A10447 Hematoxylin (Hydroxybrazilin)

A10450 Hesperidin

A10454 Hordenine

A10455 Hydralazine hydrochloride

A10456 Hydrochlorothiazide

A10458 Hydroxocobalamin (Vitamin B12a)

A10459 Hydroxyurea

A10460 Hyodeoxycholic acid

A10467 Iloperidone

A10469 Imiquimod (Aldara)

A10470 Indapamide (Lozol)

A10472 Indocyanine green

A10473 Indole-3-carbinol

A10481 Isoconazole nitrate

A10482 Isoliquiritigenin

A10489 Itraconazole (Sporanox)

A10503 Kinetin

A10509 L(+)-Rhamnose Monohydrate

A10515 Lappaconite Hydrobromide

A10517 L-Ascorbyl 6-palmitate

A10521 Leflunomide

A10524 Leucovorin Calcium

A10531 Limonin

A10533 Linezolid (PNU-100766)

A10539 Loteprednol Etabonate

A10540 Lubiprostone

A10543 LY2886721

A10551 Magnolol

A10552 Malotilate

A10557 Marbofloxacin

A10565 Meloxicam (Mobic)

A10567 Meprednisone (Betapar)

A10569 Meropenem

A10572 Mestranol

A10573 Metformin hydrochloride

A10574 Methacycline HCl (Physiomycine)

A10575 Methazolastone

A10581 Methyl Hesperidin

A10584 Metolazone

A10594 Mitotane

A10595 Mitoxantrone

A10605 Morin hydrate

A10613 Mycophenolate mofetil (CellCept)

A10614 Mycophenolic acid

A10615 Myricetin (Cannabiscetin)

A10073 Amphotericin B

A10074 Amygdalin

A10077 Andrographolide

A10083 Aprepitant (MK-0869)

A10084 Arbutin (Uva, p-Arbutin)

A10087 Artesunate

A10099 Azomycin (2-Nitroimidazole)

A10106 Azalomycin-B

A10107 Azathioprine

A10118 Aztreonam (Azactam, Cayston)

A10124 Bendamustine HCl (SDX-105)

A10126 Berberine Hydrochloride

A10127 Bergenin (Cuscutin)

A10128 Beta Carotene

A10129 Betamethasone

A10130 Betamethasone dipropionate

A10131 Betamethasone valerate

A10136 Biapenem

A10139 BIBR-1048 (Dabigatran etexilate)

A10144 Bilobalide

A10145 Bimatoprost (Lumigan)

A10146 Biochanin A (4-Methylgenistein)

A10165 BTZ043 (BTZ038, BTZ044)

A10166 Budesonide

A10167 Bumetanide

A10168 Bupivacaine hydrochloride

A10616 Myricitrin (Myricitrine)

A10621 Nanchangmycin

A10626 Naringin (Naringoside)

A10627 Naringin Dihydrochalcone

A10628 Natamycin (Pimaricin)

A10633 Neohesperidin

A10634 Neohesperidin dihydrochalcone

A10636 Nepafenac

A10651 Nobiletin (Hexamethoxyflavone)

A10652 Norfloxacin (Norxacin)

A10656 Phenprocoumon

A10663 NXY-059 (Cerovive)

A10666 Ofloxacin (DL8280)

A10668 Oleanolic Acid (Caryophyllin)

A10675 Oridonin (Isodonol)

A10676 Orlistat

A10677 Orotic acid (6-Carboxyuracil)

A10680 OstholeA10682 Oxacillin sodium monohydrate

A10685 Oxymatrine (Matrine N-oxide)

A10687 Oxytetracycline (Terramycin)

A10690 Paeonol (Peonol)

A10692 Palmatine chloride

A10694 Pamidronate Disodium

A10698 Parthenolide ((-)-Parthenolide)

A10708 Pentagastrin

A10723 Phloretin (Dihydronaringenin)

A10724 Phlorizin (Phloridzin)

A10725 Vanoxerine 2HCl (GBR-12909)

A10732 Pimecrolimus

A10734 Piperine (1-Piperoylpiperidine)

A10738 Pizotifen malate

A10741 Polydatin (Piceid)

A10744 Posaconazole

A10750 Praziquantel (Biltricide)

A10752 Prednisone (Adasone)

A10753 Prilocaine

A10758 PTC124 (Ataluren)

A10767 Quetiapine fumarate

A10772 Racecadotril (Acetorphan)

A10777 Ramelteon (TAK-375)

A10786 Rhein (Monorhein)

A10787 Rheochrysidin (Physcione)

A10790 Rifabutin

A10792 Rifapentine (Priftin)

A10793 Rifaximin (Xifaxan)

A10796 Risedronate sodium

A10814 Rutaecarpine (Rutecarpine)

A10815 Rutin (Rutoside)

A10820 Salicin (Salicoside, Salicine)

A10821 Salidroside (Rhodioloside)

A10822 Salinomycin (Procoxacin)

A10831 Sclareol

Others Others


51 52A10832 Sclareolide (Norambreinolide)

A10837 Sesamin (Fagarol)

A10840 Shikimic acid (Shikimate)

A10842 Silibinin (Silybin)

A10844 Silymarin (Silybin B)

A10846 Sinomenine (Cucoline)

A10854 Sodium orthovanadate

A10857 Sophocarpine

A10861 Spectinomycin HCl

A10864 Staurosporine

A10866 STF-62247

A10867 Stigmasterol (Stigmasterin)

A10868 Streptozotocin (Zanosar)

A10888 Tangeretin (Tangeritin)

A10889 Tanshinone I

A10890 Tanshinone IIA (Tanshinone B)

A10892 Taurine

A10894 Tazarotene

A10910 Tenoxicam

A10912 Terbinafine hydrochloride (Lamisil)

A10913 Plerixafor 8HCl (DB06809)

A10918 Indacaterol

A10920 Tetrahydropapaverine hydrochloride

A10925 Theobromine (3,7-Dimethylxanthine)

A10933 Tigecycline

A10942 Tranilast (SB 252218)

A10952 Troxerutin

A10961 Ursolic acid (Malol)

A10964 Vanillylacetone

A10986 VX-809

A10993 Xanthone (Genicide)

A11003 Yohimbine hydrochloride (Antagonil)

A11015 β-Sitosterol

A11069 Fosaprepitant dimeglumine

A11070 AG-L-59687

A11093 Nitisinone

A11094 Bexarotene (LGD1069)

A11095 URB754

A11096 UR-144

A11103 BAPTA

A11110 Folinic acid calcium salt (Leucovorin)

A11111 Rasagiline

A11113 Pneumocandin B0

A11124 Peramivir

A11128 Laquinimod (ABR-215062)

A11136 INCB8761 (PF-4136309)

A11139 Retapamulin (SB-275833)

A11185 Ribitol (Adonitol)

A11201 BMS-806 (BMS 378806)

A11214 Lurasidone (SM13496)

A11216 Entecavir

A11227 Chaetominine

A11232 Troxacitabine (SGX-145)

A11260 MLN4924

A11265 Odanacatib (MK-0822)

A11283 P005672 HCl

A11284 Cefozopran

A11294 Anguizole

A11297 Adoprazine (SLV313)

A11298 Adarotene (ST1926)

A11299 Avibactam

A11300 ASC-J9

A11301 Avosentan (SPP301)

A11302 Armodafinil

A11312 Azaphen (Pipofezine)

A11319 BMS-509744

A11323 Bardoxolone methyl (RTA 402)

A11324 Bardoxolone (CDDO)

A11330 Besifloxacin HCl

A11342 Calcipotriol monohydrate

A11346 Calcipotriol

A11359 CB 300919

A11362 Calcitetrol

A11364 Caspofungin Acetate

A11367 Calcifediol

A11401 PA-824

A11404 Chondroitin sulfate

A11406 LY2608204

A11420 Fagomine

A11435 GSK-923295

A11495 MK 0893

A11497 MK-2894

A11499 MLN4924 (HCL Salt)

A11542 Rilpivirine (R 278474, TMC 278)

A11561 Salmefamol

A11585 TMC353121

A11591 Tedizolid (TR-701)

A11593 Tonabersat (SB-220453)

A11613 Zanamivir

A11614 Zaurategrast (CDP323)

A11632 Cephalomannine

A11641 Pranoprofen

A11645 Ganciclovir

A11648 Sulbactam

A11652 Clindamycin palmitate HCl

A11653 Oseltamivir phosphate (Tamiflu)

A11654 Oxibendazole

A11655 Tioconazole

A11656 Flubendazole (Flutelmium)

A11657 Tolnaftate

A11658 Balofloxacin

A11659 Sarafloxacin hydrochloride

A11660 Prulifloxacin (Pruvel)

A11661 Rimantadine (Flumadine)

A11662 Isepamicin

A11663 Arbidol HCl

A11664 Telithromycin (Ketek)

A11669 L-Thyroxine

A11670 Noradrenaline bitartrate monohydrate

A11671 Inulin

A11672 ATP (Adenosine-Triphosphate)

A11674 Epalrestat

A11675 Risedronic acid (Actonel)

A11676 Alibendol

A11677 Genipin

A11678 Miglitol (Glyset)

A11679 NAD+

A11680 Pioglitazone (Actos)

A11681 Strontium ranelate (Protelos)

A11683 Cyclocytidine

A11684 Etidronate (Didronel)

A11685 Pamidronic acid

A11687 Prednisolone acetate (Omnipred)

A11688 Fluocinonide(Vanos)

A11689 Fenoprofen calcium

A11691 Mometasone furoate

A11698 Aspartame

A11707 Idebenone

A11710 Pramiracetam

A11711 Carisoprodol

A11714 Lafutidine

A11716 Adiphenine HCl

A11723 Naltrexone HCl

A11725 Edaravone (MCI-186)

A11726 Heparin sodium

A11735 Geniposide

A11737 Buflomedil HCl

A11741 Moxonidine HCl

A11744 Mecarbinate

A11751 Probucol

A11756 MK-0517 (Fosaprepitant)

A11757 GSK126

A11761 Merck SIP Agonist

A11769 Loxiglumide (CR1505)

A11774 Argatroban

A11781 PF 670462

A11783 GSK 1210151A (I-BET151)

A11787 Aminopterin

A11802 Atracurium besylate

A11805 Amidopyrine

A11806 Azacyclonol

A11808 Articaine HCl

A11809 Altrenogest

A11829 Butenafine HCl

A11831 Cabazitaxel

A11840 ENOblock (AP-III-a4)

A11852 Fenticonazole nitrate

A11870 Ibandronate sodium

A11874 Levosimendan

A11878 Iopromide

A11894 Nadifloxacin

A11904 Paroxetine HCl

A11910 Pyridoxine HCl

A11911 Pidotimod

A11936 ML 7 hydrochloride

A11946 OC 000459

A11958 Moxalactam Sodium

A11959 GW2580

A11963 Y320

A11973 Necrostatin-1

A11974 GW 4869

A11989 Apocynin (Acetovanillone)

A11991 Schisandrin B

A12000 Guanosine

A12026 Carnosic Acid

A12159 Ezatiostat

A12161 Catharanthine sulfate

A12163 Fenretinide

A12258 HPGDS inhibitor 1

A12323 Efaproxiral

A12325 Indisulam (E7070)

A12345 Anamorelin HCl

A12346 Anamorelin

A12347 cis-(Z)-Flupentixol dihydrochloride

A12355 Nipradilol

A12361 Pristinamycin

A12364 Nalbuphine Hydrochloride

A12365 CHIR-090

A12369 Stiripentol

A12370 ANX-510

A12380 Quarfloxin (CX-3543)

A12389 Benperidol

A12400 MifaMurtide

A12406 Apaziquone

A12407 TMPA

A12428 WF 11899A

A12432 ALPHA-ERGOCRYPTINE

A12441 Halofuginone

A12479 Siramesine Hydrochloride

A12547 Lithocholic acid

A12568 Tirasemtiv

A12569 Ametantrone

A12579 Nalfurafine hydrochloride

A12581 P7C3-A20

A12592 Ascomycin

A12634 MBX-2982

A12654 Ombrabulin

A12658 Verteporfin

A12660 Carebastine

A12666 AZ 23

A12668 Pemetrexed disodium

A12673 Pyronaridine Tetraphosphate

Others Others


53 54A12676 Salubrinal

A12686 Eltrombopag

A12687 JNJ-28312141A12691 Palifosfamide

A12696 Vancomycin

A12698 Telavancin

A12727 AMG517

A12747 JZL184

A12753 RC-3095

A12754 Tirapazamine

A12756 Cyclamic Acid

A12771 Acolbifene (EM 652, SCH57068)

A12773 Bleomycin hydrochloride

A12780 Freselestat

A12781 Ibutamoren mesylate (MK-677)

A12784 Embramine

A12793 Vofopitant (GR 205171)

A12797 Miglustat hydrochloride

A12799 Prochloraz manganese

A12801 Sapacitabine (CYC682)

A12802 Ibutamoren (MK-677)

A12803 Cardiolipin

A12806 Ravuconazole

A12807 Ceftobiprole medocaril

A12818 Doripenem

A12832 Vorapaxar (SCH 530348)

A12835 MK7622

A12838 NQDI 1

A12843 Cangrelor (AR-C69931)

A12847 a-Apo-oxytetracycline

A12852 D2PM hydrochloride

A12859 GKA50

A12861 Mirabegron

A12863 Lomifyllin

A12864 Delamanid

A12873 Tafenoquine

A12876 Pyrintegrin

A12878 SNT-207858

A12879 Tepoxalin

A12887 4-Epi Minocycline

A12895 Thiamet G

A12899 PluriSln 1

A12905 AR7

A12906 BAF312

A12908 Bioymifi

A12909 JNJ-40411813

A12910 Lupulone

A12913 Cilliobrevin D

A12931 OAC1

A12934 P7C3

A12945 StemRegenin 1 (SR1)

A12954 Monomethyl auristatin E

A12990 Lobucavir

A13007 TTNPB

A13032 AT 56

A13036 Siramesine

A13046 N6022

A13073 Clemizole

A13084 Arbidol

A13085 LODENOSINE

A13088 Trimipramine

A13089 ent Naxagolide Hydrochloride

A13091 Nimorazole

A13096 Panipenem

A13097 Ioversol

A13098 Tipiracil

A13100 Triphendiol (NV-196)

A13101 ME-143

A13106 GSK221149A (Retosiban)

A13111 R1530

A13112 GGTI-2418

A13117 NSC348884

A13119 Balamapimod (MKI-833)

A13122 Amsilarotene (TAC-101)

A13124 SNT-207707

A13134 CP-640186

A13150 XEN445

A13157 TEMPOL

A13167 AMG-47a

A13187 RI-1

A13188 SRPIN340

A13195 UNC0631

A13207 Pirodavir

A13215 (Glp1)-Apelin-13

A13230 TP808

A13235 NVP-231

A13242 Quinacrine 2HCl

A13243 Apramycin Sulfate

A13248 MGL-3196

A13251 GS-9620

A13261 Nolatrexed Dihydrochloride

A13268 Ansamitocin P-3

A13269 Caspofungin

A13270 Micafungin

A13271 Fidaxomicin

A13276 KN-93

A13279 Flurazepam dihydrochloride

A13281 Pyrroloquinoline quinone

A13292 Arzoxifene HCl

A13296 SP-420

A13297 Deferitrin (GT-56-252)

A13300 Palosuran

A13310 MK-3102

A13324 BAY57-1293

A13331 laxogenin

A13354 Harmane

A13360 ML 171

A13369 5-BrdU

A13370 BCH

A13404 FABP4 Inhibitor

A13410 Imipramine Hydrochloride

A13411 Isotetrandrine

A13455 GSK369796

A13475 SF1670

A13516 Coluracetam

A13520 Isatoribine monohydrate

A13530 Flumatinib mesylate

A13570 ML314

A13642 Etofenamate

A13663 Nifuratel

A13667 Geranylgeranylacetone

A13668 Levomefolate Calcium

A13692 PTZ-343

A13693 Gemcitabine elaidate

A13708 Atovaquone

A13716 AR-231453

A13719 Treprostinil

A13725 10058-F4

A13732 TGR5-Receptor-Agonist

A13733 NSI-189

A13734 ZLN005

A13739 SCH 54292

A13742 TC-DAPK6

A13746 FAI

A13748 GNE-7915

A13756 Cambendazole

A13764 ST 101(ZSET1446)

A13768 AdipoRon

A13783 Tirofiban Hydrochloride Hydrate

A13807 BMS303141

A13814 Atglistatin

A13819 TG 100801

A13820 TG 100572

A13826 PTC-209

A13828 APY29

A13830 (S)-Reticuline

A13831 PX 12

A13832 RPI-1

A13835 PF-06687859

A13876 C7280948

A13883 CGP 57380

A13887 TP-434

A13983 ATB 346A13990 Fosfluconazole

A14018 Chlorin E6

A14033 NHS-Biotin

A14035 Biotin Hydrazide

A14040 Biotin-X-NHS

A14041 BMPS

A14050 WW298

A14051 WK23

A14052 YH249

A14070 TAPI-1

A14071 NVP-AAM077 Tetrasodium Hydrate

A14072 STF 118804

Carbonic AnhydraseA10303 Diclofenamide

A11673 Tioxolone

A11765 Brinzolamide

CholinesteraseA10330 Donepezil hydrochloride

A13079 Donepezil

A13584 A-3 Hydrochloride

Casein Kinase 2A10344 Ellagic acid

Soluble guanylyl cyclase (sGC)A11549 Riociguat (BAY 63-2521)

A12402 YC-1

A11980 TPEN

Reagents

Integrin ReceptorsA12371 Cilengitide trifluoroacetate

A12372 Cilengitide

A12787 Firategrast (SB 683699)

Toll-like ReceptorsA12683 Toll-Like Receptor 7 Ligand II

A12841 VTX-2337

Others Others

Beta-secretase (BACE)A12825 AZD3839

A13249 AZD5423

LRRK2A12798 GSK2578215A

A12919 HG-10-102-01

A13448 CZC-25146

A13969 GNE0877

MELK

Alphabetical Product Index

Adooq Bioscience Email: [email protected] Phone: 1-866-930-6790 Fax: 1-866-333-9607Adooq Bioscience LLC. © 2015

55A12851 OTSSP167

β-lactamaseA12384 Clavulanic acid

GluconeogenesisA10419 Gatifloxacin

CholinesterasesA13079 Donepezil

Aldose ReductaseA13083 Tolrestat

Nitric Oxide SignalingA13359 Diphenyleneiodonium chloride

Adenylyl CyclaseA12917 Forskolin

A13586 NKY 80

IDH1A12923 IDH-C227

LSD1 inhibitorA12927 LSD1-C76

Casein Kinase 1

Sigma-1 receptor

Lipoxygenase

A13574 LH 846

A13949 D4476

A13346 MK 886

A12504 S1RA

Others

A 740003 ------------------------------------------------------ 43A 803467 ------------------------------------------------------ 39A 83-01 -------------------------------------------------------- 30A 922500 ------------------------------------------------------ 46A 967079 ------------------------------------------------------ 40A-3 Hydrochloride ------------------------------------------ 54A-317491 sodium salt hydrate --------------------------- 43A-419259 ----------------------------------------------------- 27A-443654 ----------------------------------------------------- 20A66 ------------------------------------------------------------- 21A-674563 ----------------------------------------------------- 20A-769662 ----------------------------------------------------- 40A-867744 ----------------------------------------------------- 39A-966492 -------------------------------------------------------9a-Apo-oxytetracycline -------------------------------------- 53Abacavir --------------------------------------------------- 12,13Abacavir sulfate ------------------------------------------ 12,13Abarelix Acetate --------------------------------------------- 46AB-FUBINACA ------------------------------------------------ 44Abiraterone (CB-7598)------------------------------------- 13Abiraterone Acetate (CB7630) --------------------------- 13ABT ------------------------------------------------------------- 13ABT-199 ---------------------------------------------------------1ABT-263 (Navitoclax) ----------------------------------------1ABT333 -------------------------------------------------------- 18ABT-492 ------------------------------------------------------- 48ABT-737 ---------------------------------------------------------1ABT-751 ------------------------------------------------------- 11ABT-888 (Veliparib) ------------------------------------------9AC220 (Quizartinib) ---------------------------------------- 25Acadesine (Aicar,NSC 105823) --------------------------- 40Acarbose ------------------------------------------------------ 48Acemetacin (Emflex) --------------------------------------- 15Acetaminophen ---------------------------------------------- 15Acetanilide ---------------------------------------------------- 48Acetylcysteine ------------------------------------------------ 42Aciclovir (Acyclovir) ------------------------------------------5Acipimox ----------------------------------------------------- 48Acitazanolast ------------------------------------------------- 48Acitretin ------------------------------------------------------- 48Acolbifene (EM 652, SCH57068) ------------------------- 53Actinomycin D ----------------------------------------------- 12ACY-1215 (Rocilinostat) ----------------------------------- 17Adapalene ---------------------------------------------------- 48Adarotene (ST1926) ---------------------------------------- 51Adefovir dipivoxil ------------------------------------------- 12Adenine sulfate ---------------------------------------------- 18Adenosine ----------------------------------------------------- 44Adiphenine HCl ---------------------------------------------- 52AdipoRon ----------------------------------------------------- 54ADL5859 HCl ------------------------------------------------- 42Adoprazine (SLV313) --------------------------------------- 51Adrenalone HCl ---------------------------------------------- 41Adriamycin --------------------------------------------------- 11ADX-47273 --------------------------------------------------- 43AEE788 ------------------------------------------------------2,23Aesculin (Esculin) ------------------------------------------- 48AG 957 --------------------------------------------------------- 28AG-014699 (Rucaparib) -------------------------------------9AG-1024 (Tyrphostin) -------------------------------------- 24AG-1288 ------------------------------------------------------- 28AG14361 ----------------------------------------------------- 10AG-1478 (Tyrphostin AG-1478) -----------------------3,23AG-17 --------------------------------------------------------3,24AG-490 ------------------------------------------------------2,23AGI-5198 (IDH-C35) ---------------------------------------- 15AGI-6780 ------------------------------------------------------ 15AG-L-59687 -------------------------------------------------- 51Agomelatine -------------------------------------------------- 41AK-7 ----------------------------------------------------------- 17AKT inhibitor VIII (AKTI-1/2) ---------------------------- 20Albendazole ------------------------------------------------4,24Alendronate sodium hydrate ----------------------------- 12Alfacalcidol --------------------------------------------------- 48Alfuzosin HCl ------------------------------------------------- 41Alibendol ------------------------------------------------------ 52Aliskiren (CGP 60536) ------------------------------------- 45Aliskiren hemifumarate ------------------------------------ 45Alizarin -------------------------------------------------------- 48Allopurinol --------------------------------------------------- 48Allopurinol sodium ----------------------------------------- 48Almotriptan malate (Axert) ------------------------------- 41Aloe-emodin -------------------------------------------------- 48Alogliptin Benzoate ----------------------------------------- 33Aloin (Barbaloin) -------------------------------------------- 48Alosetron ------------------------------------------------------ 41

alpha-Amyloid Precursor Protein Modulator ---------- 30ALPHA-ERGOCRYPTINE ----------------------------------- 52Altrenogest --------------------------------------------------- 52Altretamine --------------------------------------------------- 48Alvimopan (ADL 8-2698) ---------------------------------- 15AM 580 -------------------------------------------------------- 46AM251 --------------------------------------------------------- 44Ambrisentan (BSF 208075) ------------------------------- 43AMD 070 ------------------------------------------------------ 43AMD 3465 Hexahydrobromide --------------------------- 43AMD3100 (Plerixafor) ------------------------------------- 43Ametantrone ------------------------------------------------- 52Amfebutamone (Bupropion) ------------------------------ 42AMG 073 (Cinacalcet) -------------------------------------- 38AMG 208 ------------------------------------------------------ 25AMG 900 --------------------------------------------------------9AMG-073 HCl (Cinacalcet HCl) --------------------------- 38AMG-458 ------------------------------------------------------ 25AMG-47a ------------------------------------------------------ 53AMG517 ------------------------------------------------------- 53AMG-Tie2-1 -------------------------------------------------- 27Amidopyrine ------------------------------------------------- 52Amiloride hydrochloride ---------------------------------- 39Amiloride hydrochloride dihydrate --------------------- 39Aminocaproic acid (Amicar) ------------------------------ 48Aminophylline ----------------------------------------------- 44Aminopterin -------------------------------------------------- 52Amisulpride -------------------------------------------------- 42Amlodipine --------------------------------------------------- 38Amlodipine besylate (Norvasc) -------------------------- 38Ammonium Glycyrrhizinate (AMGZ) -------------------- 48Amonafide (AS1413) --------------------------------------- 11Amorolfine Hydrochloride -------------------------------- 48Ampalex (CX-516) ------------------------------------------- 38Amphotericin B ---------------------------------------------- 49Amprenavir --------------------------------------------------- 32Amrubicin ---------------------------------------------------- 11Amsacrine ---------------------------------------------------- 12Amsilarotene (TAC-101) ----------------------------------- 53Amygdalin ---------------------------------------------------- 49AN2728 ------------------------------------------------------- 14Anacetrapib (MK-0859) ------------------------------------ 19Anamorelin -------------------------------------------------- 52Anamorelin HCl ---------------------------------------------- 52Anastrozole --------------------------------------------------- 46Andarine (GTX-007) ---------------------------------------- 45Andrographolide -------------------------------------------- 49Anguizole ----------------------------------------------------- 51Aniracetam --------------------------------------------------- 17Ansamitocin P-3 --------------------------------------------- 53ANX-510 ------------------------------------------------------- 52AP24534 (Ponatinib) --------------------------------------- 26AP26113 ----------------------------------------------------3,24AP26113 ------------------------------------------------------ 26Apatinib (YN968D1) --------------------------------------3,24Apatinib (YN968D1) --------------------------------------- 24Apaziquone --------------------------------------------------- 52Apicidin ------------------------------------------------------- 17Apigenin ------------------------------------------------------- 13Apixaban (BMS-562247-01) ------------------------------ 17Apocynin (Acetovanillone) -------------------------------- 52Apoptosis Activator 2-------------------------------------1,30Apramycin Sulfate ------------------------------------------- 53Apremilast (CC 10004) ------------------------------------- 14Aprepitant (MK-0869) ------------------------------------- 49APY29 --------------------------------------------------------- 54AR-231453 --------------------------------------------------- 54AR-42 (HDAC-42) ------------------------------------------- 17AR7 ------------------------------------------------------------- 53AR-A 014418 ------------------------------------------------- 36Arbidol -------------------------------------------------------- 53Arbidol HCl --------------------------------------------------- 51Arbutin (Uva, p-Arbutin) ---------------------------------- 49AR-C155858 -------------------------------------------------- 37Arctigenin -------------------------------------------------------6Arecoline ------------------------------------------------------ 42Arformoterol tartrate--------------------------------------- 41Argatroban --------------------------------------------------- 52Aripiprazole (Abilify) --------------------------------------- 41Armodafinil --------------------------------------------------- 51ARN-509 ------------------------------------------------------ 41ARQ 197 ------------------------------------------------------- 25ARRY334543 -----------------------------------------------3,23Arry-380 ----------------------------------------------------3,23Arry-520 ------------------------------------------------------ 18ARRY-543 ---------------------------------------------------3,24Artemether (SM-224) -------------------------------------- 30Artemisinin --------------------------------------------------- 37Artesunate ---------------------------------------------------- 49Articaine HCl ------------------------------------------------- 52Arzoxifene HCl ----------------------------------------------- 53

AS 602801 (Bentamapimod) -------------------------------6AS-252424 ---------------------------------------------------- 21AS-604850 ---------------------------------------------------- 21AS-605240 ---------------------------------------------------- 20AS703026 -------------------------------------------------------5Asaraldehyde (Asaronaldehyde) ------------------------- 15ASC-J9 --------------------------------------------------------- 51Ascomycin ---------------------------------------------------- 52Asenapine maleate ------------------------------------------ 41Asiatic acid -----------------------------------------------------6Asiaticoside -----------------------------------------------------6ASP3026 ------------------------------------------------------ 26Aspartame ---------------------------------------------------- 52AST-1306 ----------------------------------------------------3,23AST-6 ---------------------------------------------------------2,23Astragaloside A ---------------------------------------------- 30Asunaprevir (BMS-650032) ------------------------------ 31AT 56 ----------------------------------------------------------- 53AT101 ------------------------------------------------------------1AT13387 ------------------------------------------------------ 32AT-406 -----------------------------------------------------------2AT7519 ----------------------------------------------------------8AT7519 HCl -----------------------------------------------------8AT7867 -------------------------------------------------------- 20AT9283 -------------------------------------------------------- 29AT9283 ---------------------------------------------------------9Atazanavir ---------------------------------------------------- 32Atazanavir sulfate (BMS-232632-05) ------------------- 32ATB 346 ------------------------------------------------------- 54ATB-337 ------------------------------------------------------- 15Atglistatin ----------------------------------------------------- 54Atorvastatin -------------------------------------------------- 19Atorvastatin calcium ---------------------------------------- 19Atovaquone --------------------------------------------------- 54ATP (Adenosine-Triphosphate) -------------------------- 52Atracurium besylate ---------------------------------------- 52Atropine ------------------------------------------------------ 42Aurora A Inhibitor I -------------------------------------------9AUY922 (NVP-AUY922) ------------------------------------ 32AV-412 -------------------------------------------------------3,23Avanafil -------------------------------------------------------- 14Avasimibe (CI-1011)---------------------------------------- 13Avibactam ----------------------------------------------------- 51AVL-292 ------------------------------------------------------- 28Avosentan (SPP301) ---------------------------------------- 51AWD 131-138 ------------------------------------------------ 42Axitinib ------------------------------------------------------4,24AZ 23 ----------------------------------------------------------- 52AZ 3146 ------------------------------------------------------- 18AZ-20 ---------------------------------------------------------- 40AZ628 ------------------------------------------------------------7AZ-960 --------------------------------------------------------- 29Azacitidine(Vidaza) ----------------------------------------- 19Azacyclonol --------------------------------------------------- 52Azalomycin-B ------------------------------------------------ 49Azaphen (Pipofezine) -------------------------------------- 51Azathioprine ------------------------------------------------- 49AZD1080 ------------------------------------------------------ 36AZD1152-HQPA (Barasertib) -------------------------------9AZD1480 ------------------------------------------------------ 29AZD1981 ------------------------------------------------------ 46AZD2014 ------------------------------------------------------ 22AZD-2461 ----------------------------------------------------- 10AZD2858 ------------------------------------------------------ 36AZD3463 ------------------------------------------------------ 26AZD3514 ------------------------------------------------------ 45AZD3839 ------------------------------------------------------ 54AZD4547 ----------------------------------------------------3,24AZD5363 ------------------------------------------------------ 20AZD5423 ------------------------------------------------------ 54AZD5438 --------------------------------------------------------8AZD6244 (Selumetinib) -------------------------------------5AZD6482 ------------------------------------------------------ 20AZD7762 --------------------------------------------------------7AZD8055 ------------------------------------------------------ 22AZD8330 -------------------------------------------------------5AZD8931 ----------------------------------------------------2,23AZD-9291 ---------------------------------------------------3,24Azelastine hydrochloride (Allergodil) ------------------ 42Azelnidipine -------------------------------------------------- 38Azilsartan (TAK-536) --------------------------------------- 43Azithromycin (Zithromax) -------------------------------- 18Azomycin (2-Nitroimidazole) ----------------------------- 49Aztreonam (Azactam, Cayston) -------------------------- 49

A

B

Alphabetical Product Index Alphabetical Product Index

Adooq Bioscience Adooq BioscienceEmail: [email protected] Phone: 1-866-930-6790 Fax: 1-866-333-9607 Email: [email protected] Phone: 1-866-930-6790 Fax: 1-866-333-9607

BAF312 -------------------------------------------------------- 53Bafetinib (INNO-406) -------------------------------------- 26Baicalein ------------------------------------------------------ 13Baicalin -------------------------------------------------------- 42Balamapimod (MKI-833) ---------------------------------- 53Balapiravir (R1626) ---------------------------------------- 31Balicatib ------------------------------------------------------- 34Balofloxacin -------------------------------------------------- 51BAM 7 ------------------------------------------------------------1BAN ORL 24 -------------------------------------------------- 42BAPTA --------------------------------------------------------- 51BAPTA tetrapotassium ------------------------------------- 38BAPTA/AM --------------------------------------------------- 38Bardoxolone (CDDO) --------------------------------------- 51Bardoxolone methyl (RTA 402) -------------------------- 51Baricitinib (LY3009104) ----------------------------------- 29Batimastat (BB-94) ----------------------------------------- 33BAY 1000394 ---------------------------------------------------8Bay 11-7821 ----------------------------------------------------1Bay 60-7550 -------------------------------------------------- 14BAY 61-3606 ------------------------------------------------- 27Bay 65-1942 -------------------------------------------------- 28Bay 65-1942 HCl -------------------------------------------- 28BAY 80-6946 ------------------------------------------------- 21BAY 87-2243 ---------------------------------------------------5BAY57-1293 -------------------------------------------------- 53BAY-u 3405 --------------------------------------------------- 43Bazedoxifene acetate --------------------------------------- 44BCH------------------------------------------------------------- 54BCX 1470------------------------------------------------------ 33BCX 1470 methanesulfonate ------------------------------ 33Belinostat (PXD101) ---------------------------------------- 16Benazepril hydrochloride --------------------------------- 45Bendamustine HCl (SDX-105) ---------------------------- 49Benidipine hydrochloride --------------------------------- 38Benperidol ---------------------------------------------------- 52Benserazide hydrochloride (Serazide) ------------------ 42Bepotastine --------------------------------------------------- 42Bepotastine Besilate ---------------------------------------- 42Berberine Hydrochloride ---------------------------------- 49Bergenin (Cuscutin) ---------------------------------------- 49Besifloxacin HCl --------------------------------------------- 51Beta Carotene ------------------------------------------------ 49Beta-Lapachone --------------------------------------------- 11Betamethasone ---------------------------------------------- 49Betamethasone dipropionate ----------------------------- 49Betamethasone valerate ---------------------------------- 49Betaxolol ------------------------------------------------------ 41Betaxolol hydrochloride ----------------------------------- 41Bethanechol chloride --------------------------------------- 42Betrixaban ---------------------------------------------------- 18Betulinic acid ------------------------------------------------- 12Bexarotene (LGD1069) ------------------------------------ 51BEZ235 (NVP-BEZ235) ------------------------------------ 20BGJ398 (NVP-BGJ398) -----------------------------------3,24B-HT 920 2HCl ----------------------------------------------- 42BI 2536 -------------------------------------------------------- 10BI6727 (Volasertib) ----------------------------------------- 10Biapenem ----------------------------------------------------- 49Bibf1120 (Vargatef) --------------------------------------4,24BIBR 1532 ---------------------------------------------------- 12BIBR 953 (Dabigatran, Pradaxa) ------------------------- 33BIBR-1048 (Dabigatran etexilate) ----------------------- 49BIBW2992 (Afatinib) -------------------------------------2,23BIBX 1382 --------------------------------------------------3,23Bicalutamide (Casodex) ------------------------------------ 45BI-D1870 ------------------------------------------------------ 23Bifemelane hydrochloride --------------------------------- 17BIIB021 ------------------------------------------------------- 32BIIE 0246 ----------------------------------------------------- 43Bilastine ------------------------------------------------------- 42Bilobalide ----------------------------------------------------- 49Bimatoprost (Lumigan) ------------------------------------ 49BINA ----------------------------------------------------------- 43Bindarit ------------------------------------------------------- 28Biochanin A (4-Methylgenistein) ------------------------ 49Biotin Hydrazide -------------------------------------------- 54Biotin-X-NHS ------------------------------------------------- 54Bioymifi ------------------------------------------------------- 53Biperiden hydrochloride ----------------------------------- 42Birinapant (TL32711) ----------------------------------------2Bisoprolol ----------------------------------------------------- 41Bisoprolol fumarate ---------------------------------------- 41BIX 01294 ----------------------------------------------------- 47BIX 02189 ------------------------------------------------------5BIX02188 -------------------------------------------------------5BKM120 (NVP-BKM120) ---------------------------------- 21Bleomycin hydrochloride ---------------------------------- 53Bleomycin sulfate ------------------------------------------- 18Blonanserin -------------------------------------------------- 42BM-1074 --------------------------------------------------------1

BML-190 ------------------------------------------------------ 44BML-275 ------------------------------------------------------ 40BML-277 --------------------------------------------------------8BMN673 ------------------------------------------------------- 10BMPS ----------------------------------------------------------- 54BMS 299897 -------------------------------------------------- 35BMS 345541 -------------------------------------------------- 28BMS 433796 -------------------------------------------------- 35BMS 599626 (AC480) ------------------------------------3,23BMS-265246 ---------------------------------------------------8BMS303141 -------------------------------------------------- 54BMS-509744 ------------------------------------------------- 51BMS-536924 ------------------------------------------------- 24BMS564929 -------------------------------------------------- 45BMS-690514 -----------------------------------------------3,23BMS-690514 ------------------------------------------------- 24BMS-707035 ------------------------------------------------- 33BMS-708163 ------------------------------------------------- 35BMS-740808 ------------------------------------------------- 18BMS-754807 ------------------------------------------------- 24BMS-777607 ------------------------------------------------- 25BMS-777607 ------------------------------------------------- 28BMS-790052 --------------------------------------------- 31,31BMS-790052 2HCl ------------------------------------------ 31BMS-794833 ------------------------------------------------- 25BMS-806 (BMS 378806) ----------------------------------- 51BMS-833923 (XL-139) ------------------------------------- 36BMS-863233 (XL-413) ---------------------------------------8BMS-911543 ------------------------------------------------- 29BMS-927711 ------------------------------------------------- 43BMY 7378 ----------------------------------------------------- 41Boceprevir (SCH-503034) --------------------------------- 31Bopindolol malonate --------------------------------------- 45Bortezomib (Velcade) -------------------------------------- 30Bosentan ------------------------------------------------------ 43Bosutinib (SKI-606) ---------------------------------------- 27BP897 ---------------------------------------------------------- 42BRAF inhibitor -------------------------------------------------7BRD9757 ------------------------------------------------------ 17Brefeldin A ---------------------------------------------------- 37Brequinar ----------------------------------------------------- 15Bretazenil ----------------------------------------------------- 39Brinzolamide ------------------------------------------------- 54Brivanib (BMS-540215) ---------------------------------4,24Brivanib alaninate (BMS-582664) ---------------------4,24BRL 52537 hydrochloride --------------------------------- 42BRL-15572 --------------------------------------------------- 41Bromfenac sodium ------------------------------------------ 16Bromosporine ------------------------------------------------ 34Brompheniramine ------------------------------------------ 42Bryostatin 1 -------------------------------------------------- 49BS-181 HCl------------------------------------------------------8BSI-201 (Iniparib) ------------------------------------------ 10BTZ043 (BTZ038, BTZ044) ------------------------------- 49Budesonide --------------------------------------------------- 49Bufalin --------------------------------------------------------- 37Buflomedil HCl ----------------------------------------------- 52Bufotalin ------------------------------------------------------ 37Bumetanide -------------------------------------------------- 49Bupivacaine hydrochloride -------------------------------- 49Busulfan (Myleran, Busulfex) ----------------------------- 49Butein --------------------------------------------------------3,24Butenafine HCl ----------------------------------------------- 52Butylscopolamine BR -------------------------------------- 49BX-795 --------------------------------------------------------- 23BX-912 --------------------------------------------------------- 23BYL719 -------------------------------------------------------- 21

CC646 ----------------------------------------------------------- 47C7280948 ----------------------------------------------------- 54CA-074 --------------------------------------------------------- 34Cabazitaxel --------------------------------------------------- 52Cabergoline --------------------------------------------------- 42Caffeic acid ---------------------------------------------------- 49CAL-101 (GS-1101) ----------------------------------------- 20Calcifediol ----------------------------------------------------- 51Calcipotriol --------------------------------------------------- 51Calcipotriol monohydrate --------------------------------- 51Calcitetrol ----------------------------------------------------- 51Calcitriol (Rocaltrol) ---------------------------------------- 49Cambendazole ----------------------------------------------- 54Camostat mesylate ------------------------------------------ 33Camptothecin ------------------------------------------------ 11Canagliflozin ------------------------------------------------- 37Candesartan (Atacand)------------------------------------- 45

Candesartan cilexetil (Atacand) -------------------------- 45Canertinib (CI-1033) -------------------------------------2,23Cangrelor (AR-C69931) ------------------------------------ 53Capecitabine (Xeloda) -------------------------------------- 16Capsaicin ------------------------------------------------------ 32Captopril ------------------------------------------------------ 33Carbamazepine ---------------------------------------------- 16Carbidopa ----------------------------------------------------- 49Carboplatin --------------------------------------------------- 18Cardiolipin ---------------------------------------------------- 53Carebastine --------------------------------------------------- 52Carisoprodol ------------------------------------------------- 52Carmofur ------------------------------------------------------ 16Carnosic Acid ------------------------------------------------- 52Carvedilol ----------------------------------------------------- 41CASIN ---------------------------------------------------------- 43Caspofungin -------------------------------------------------- 53Caspofungin Acetate ---------------------------------------- 51Catharanthine sulfate--------------------------------------- 52CAY10505 ----------------------------------------------------- 21CB 300919 ---------------------------------------------------- 51CC-401 -----------------------------------------------------------6CCG-63802 ---------------------------------------------------- 43CCT128930 --------------------------------------------------- 20CCT129202 -----------------------------------------------------9CCT137690 -----------------------------------------------------9CCT239065 --------------------------------------------------- 18CCT241533 -----------------------------------------------------9CCT241533 ----------------------------------------------------7CD 437 --------------------------------------------------------- 46Cediranib (AZD2171) ------------------------------------4,24Cefaclor -------------------------------------------------------- 49Cefdinir -------------------------------------------------------- 49Cefditoren pivoxil ---------------------------------------------5Cefoselis sulfate---------------------------------------------- 49Cefozopran --------------------------------------------------- 51Cefprozil hydrate (Cefzil) ---------------------------------- 49Ceftiofur hydrochloride ------------------------------------ 49Ceftobiprole medocaril ------------------------------------- 53Celastrol ------------------------------------------------------- 49Celecoxib ------------------------------------------------------ 15Celgosivir ----------------------------------------------------- 31CEP-18770 ---------------------------------------------------- 31CEP-28122 ---------------------------------------------------- 26CEP33779 ----------------------------------------------------- 29Cephalomannine -------------------------------------------- 51Cerpegin ------------------------------------------------------- 46Cerubidine ---------------------------------------------------- 11Cetaben -------------------------------------------------------- 45Cetirizine Dihydrochloride -------------------------------- 42Cevipabulin (TTI-237) ------------------------------------- 12CFTR-Inhibitor-II -------------------------------------------- 40CGI1746 ------------------------------------------------------- 28CGK 733 ------------------------------------------------------- 40CGP 3466B maleate ----------------------------------------- 15CGP 57380 ---------------------------------------------------- 54CGP-52411 --------------------------------------------------3,24CGP60474-------------------------------------------------------8CGP77675----------------------------------------------------- 27CGS 21680 hydrochloride --------------------------------- 44CH5132799 --------------------------------------------------- 21CH5424802 --------------------------------------------------- 26Chaetocin ----------------------------------------------------- 47Chaetominine ------------------------------------------------ 51CHC ------------------------------------------------------------- 38Chelerythrine Chloride ------------------------------------- 30Chenodeoxycholic acid ------------------------------------- 49CHIR-090 ----------------------------------------------------- 52CHIR-124 --------------------------------------------------------7CHIR-98014 -------------------------------------------------- 36CHIR-99021 -------------------------------------------------- 36Chloramphenicol -------------------------------------------- 13Chlorin E6----------------------------------------------------- 54Chlormezanone (Trancopal) ------------------------------ 49Chlorogenic acid --------------------------------------------- 49Chlorothiazide ----------------------------------------------- 49Chloroxine --------------------------------------------------4,24Chlorpheniramine maleate -------------------------------- 42Chlorpromazine hydrochloride -------------------------- 19Chlorprothixene --------------------------------------------- 49Chondroitin sulfate ----------------------------------------- 51CHR2797 (Tosedostat) ------------------------------------- 33Chrysin -------------------------------------------------------- 49Chrysophanic acid (Chrysophanol) --------------------2,23CI994 (Tacedinaline) --------------------------------------- 17Ciclopirox ----------------------------------------------------- 37CID 2011756 ------------------------------------------------- 30CID 755673 --------------------------------------------------- 30Cidofovir (Vistide) ------------------------------------------ 49Cilazapril monohydrate ------------------------------------ 45Cilengitide ---------------------------------------------------- 54

Cilengitide trifluoroacetate-------------------------------- 54Cilliobrevin D------------------------------------------------- 53Cilnidipine ---------------------------------------------------- 38Cilomilast (SB-207499) ------------------------------------ 14Cilostazol ------------------------------------------------------ 14Ciluprevir (BILN 2061) ------------------------------------ 31Cimetidine ---------------------------------------------------- 42Cinchonidine ------------------------------------------------- 49Cinobufagin --------------------------------------------------- 37Ciprofibrate --------------------------------------------------- 45Ciproxifan ----------------------------------------------------- 42Ciproxifan maleate ------------------------------------------ 42cis-(Z)-Flupentixol dihydrochloride --------------------- 52Cisplatin ------------------------------------------------------- 18Citalopram Hydrobromide -------------------------------- 38CK-1827452 (Omecamtiv mecarbil) -------------------- 38CK-636 --------------------------------------------------------- 12Cladribine ----------------------------------------------------- 16Clafen (Cyclophosphamide) ------------------------------- 18Clarithromycin ----------------------------------------------- 49Clavulanic acid ---------------------------------------------- 55Clemastine fumarate---------------------------------------- 42Clemizole------------------------------------------------------ 53Clenbuterol hydrochloride -------------------------------- 45Clevidipine ---------------------------------------------------- 38Clindamycin hydrochloride ------------------------------- 49Clindamycin palmitate HCl -------------------------------- 51Clinofibrate --------------------------------------------------- 45Clofarabine --------------------------------------------------- 18Clofibrate ----------------------------------------------------- 49Clomifene citrate -------------------------------------------- 44Clomipramine hydrochloride ----------------------------- 41Clonidine hydrochloride ----------------------------------- 41Clopidogrel (Plavix)----------------------------------------- 43Cloprostenol (sodium salt) -------------------------------- 43Clotrimazole -------------------------------------------------- 13Cloxacillin sodium ------------------------------------------- 49Clozapine ----------------------------------------------------- 42CNX-1351 ----------------------------------------------------- 22CNX-2006 ---------------------------------------------------3,24CNX-774 ------------------------------------------------------- 28Cobicistat(GS-9350) ---------------------------------------- 13Coenzyme Q10 (CoQ10) ----------------------------------- 49Colchicine ----------------------------------------------------- 11Coluracetam -------------------------------------------------- 54Combretastatin A4 --------------------------------------------5Compound 401 ---------------------------------------------- 23Cortisone acetate -------------------------------------------- 49Costunolide --------------------------------------------------- 12CP 945598 hydrochloride --------------------------------- 44CP-466722 ---------------------------------------------------- 40CP-547632 --------------------------------------------------4,24CP-640186 --------------------------------------------------- 53CP-673451 --------------------------------------------------3,24CP-690550 (Tofacitinib citrate) -------------------------- 29CP-724714 --------------------------------------------------2,23CP-91149 ----------------------------------------------------- 46CPI-203 -------------------------------------------------------- 34CPI-613 -------------------------------------------------------- 15Crenolanib (CP-868596) ---------------------------------3,24Crotamiton---------------------------------------------------- 49Cryptotanshinone ------------------------------------------- 29Crystal violet ------------------------------------------------- 49CTEP ----------------------------------------------------------- 43CTS-1027 ----------------------------------------------------- 33CUDC-101 ----------------------------------------------------- 16CUDC-305 (DEBIO-0932 ) --------------------------------- 33CUDC-907 ----------------------------------------------------- 17Curcumol ------------------------------------------------------ 49CVT 6883 ----------------------------------------------------- 44CW069 --------------------------------------------------------- 12CX-4945 (Silmitasertib) ------------------------------------ 30CX-5461 ------------------------------------------------------- 18CX-6258 ------------------------------------------------------- 29CYC116 ------------------------------------------------------4,24CYC116 ---------------------------------------------------------9Cyclamic Acid ------------------------------------------------ 53Cyclocytidine ------------------------------------------------- 52Cycloheximide (Actidione) -------------------------------- 18Cyclopamine -------------------------------------------------- 35Cyclophosphamide monohydrate --------------------------2Cyclosporin A ------------------------------------------------ 49Cyclovirobuxin D (Bebuxine) ----------------------------- 49Cynarin ------------------------------------------------------- 38Cyproheptadine hydrochloride -------------------------- 42Cyproterone acetate ---------------------------------------- 19Cyt387 --------------------------------------------------------- 29CYT997 -------------------------------------------------------- 11Cytarabine ---------------------------------------------------- 49Cytisine (Baphitoxine, Sophorine) ----------------------- 49CZC24832 ----------------------------------------------------- 21

CZC-25146 --------------------------------------------------- 54

DD-106669 ----------------------------------------------------- 21D2PM hydrochloride --------------------------------------- 53D4476 --------------------------------------------------------- 55Dabrafenib (GSK2118436A) -------------------------------7Dacarbazine -------------------------------------------------- 18Daidzein ------------------------------------------------------- 49Daidzin -------------------------------------------------------- 49Danoprevir (RG7227) -------------------------------------- 30Danusertib (PHA-739358) ----------------------------------9Dapagliflozin (BMS512148) ------------------------------ 37Daphnetin ----------------------------------------------------- 16Dapivirine ----------------------------------------------------- 13Dapoxetine hydrochloride --------------------------------- 41DAPT (GSI-IX) ------------------------------------------------ 35Daptomycin --------------------------------------------------- 49Darifenacin --------------------------------------------------- 42Darunavir Ethanolate (Prezista) ------------------------- 32Dasatinib (BMS-354825) ---------------------------------- 27DBeq ----------------------------------------------------------- 48DCC-2036 (Rebastinib) ------------------------------------ 26D-Cycloserine ------------------------------------------------ 49Decitabine ---------------------------------------------------- 16Decitabine ---------------------------------------------------- 19Deferasirox --------------------------------------------------- 28Deferitrin (GT-56-252) ------------------------------------- 53Deflazacort --------------------------------------------------- 49Deforolimus (Ridaforolimus) ----------------------------- 22Degarelix acetate -------------------------------------------- 46Deguelin ------------------------------------------------------- 20Dehydroepiandrosterone ---------------------------------- 41Delamanid ---------------------------------------------------- 53Delavirdine mesylate --------------------------------------- 12Delphinidin chloride --------------------------------------3,24Delphinidin chloride --------------------------------------- 24Deltarasin-HCl ----------------------------------------------- 14Desmopressin ------------------------------------------------ 43Desonide ------------------------------------------------------ 49Detomidine hydrochloride -------------------------------- 41Dexamethasone ---------------------------------------------- 49Dexrazoxane Hydrochloride ------------------------------ 49D-glutamine -------------------------------------------------- 49Diazepinomicin ------------------------------------------------7Diclofenac sodium ------------------------------------------ 15Diclofenamide ------------------------------------------------ 54Diclofensine -------------------------------------------------- 49Didanosine ---------------------------------------------------- 49Dienestrol ----------------------------------------------------- 49Dienogest ----------------------------------------------------- 44Diethylstilbestrol -------------------------------------------- 38Dihydroartemisinin ----------------------------------------- 49Dihydromyricetin (Ampeloptin) ------------------------- 49Diltiazem HCl ------------------------------------------------- 38Dimebon dihydrochloride --------------------------------- 14Dimesna (BNP7787) ---------------------------------------- 49Dinaciclib (SCH 727965) ------------------------------------8Dioscin (Collettiside III) ----------------------------------- 49Diosgenin ----------------------------------------------------- 49Diosmetin ----------------------------------------------------- 49Diosmin ------------------------------------------------------- 49Diphenhydramine hcl -------------------------------------- 49Diphenyleneiodonium chloride -------------------------- 55Dipyridamole------------------------------------------------- 38Disulfiram ----------------------------------------------------- 30Divalproex sodium ------------------------------------------ 49DL-Adrenaline ----------------------------------------------- 41DL-Carnitine hydrochloride ------------------------------- 49D-Mannitol ---------------------------------------------------- 49DMH-1 --------------------------------------------------------- 28DMOG ---------------------------------------------------------- 15DMXAA (ASA404) ---------------------------------------------4DNQX ---------------------------------------------------------- 38Dobutamine hydrochloride ------------------------------- 41Docetaxel (Taxotere) --------------------------------------- 12Docosanol ----------------------------------------------------- 49Dofetilide------------------------------------------------------ 49Domperidone ------------------------------------------------ 42Donepezil ----------------------------------------------------- 54Donepezil ----------------------------------------------------- 55Donepezil hydrochloride ---------------------------------- 54Dopamine hydrochloride ---------------------------------- 42Doramapimod (BIRB-796) ----------------------------------6Doripenem ---------------------------------------------------- 53Doripenem Hydrate ----------------------------------------- 49

Dorzolamide HCL ------------------------------------------- 49Dovitinib (TKI-258) ----------------------------------------- 25Dovitinib Dilactic acid -------------------------------------- 25Doxazosin mesylate ----------------------------------------- 41Doxercalciferol ----------------------------------------------- 49Drospirenone ------------------------------------------------ 44Drospirenone ------------------------------------------------ 44Droxinostat --------------------------------------------------- 16Duloxetine ---------------------------------------------------- 41Duloxetine HCl ----------------------------------------------- 41Dutasteride (Avodart) ----------------------------------------5Dynasore ------------------------------------------------------ 37Dyphylline ---------------------------------------------------- 44

EE 2012 --------------------------------------------------------- 35E-4031 dihydrochloride ----------------------------------- 39E-7050 (Golvatinib) -----------------------------------4,24,25E7080 (Lenvatinib) ---------------------------------------4,24Ecdysone ------------------------------------------------------ 49Econazole nitrate -------------------------------------------- 49Edaravone (MCI-186) -------------------------------------- 52Efaproxiral ---------------------------------------------------- 52EGT1442 ------------------------------------------------------ 37EHop-016 ----------------------------------------------------- 11EHT 1864 ----------------------------------------------------- 43Elacridar ------------------------------------------------------ 37Elesclomol ---------------------------------------------------- 32Eletriptan ----------------------------------------------------- 41Eletriptan hydrobromide ---------------------------------- 41Ellagic acid ---------------------------------------------------- 54Eltrombopag ------------------------------------------------- 53Elvitegravir (GS-9137) ------------------------------------- 33Embramine --------------------------------------------------- 53EMD-1214063 ----------------------------------------------- 25Emodin -------------------------------------------------------- 49Empagliflozin ------------------------------------------------ 37Emtricitabine ------------------------------------------------ 12Enalapril maleate ------------------------------------------- 42Enalaprilat dihydrate --------------------------------------- 45ENMD-2076 -------------------------------------------------- 25ENOblock (AP-III-a4) --------------------------------------- 52ent Naxagolide Hydrochloride ---------------------------- 53Entecavir ------------------------------------------------------ 51Epalrestat ----------------------------------------------------- 52Epirubicin ----------------------------------------------------- 18Epirubicin Hydrochloride --------------------------------- 11Epothilone A ------------------------------------------------- 12Epothilone B (EPO906) ------------------------------------ 12Epothilone D ------------------------------------------------- 12Eprosartan ---------------------------------------------------- 43Eprosartan mesylate ---------------------------------------- 43EPZ004777 --------------------------------------------------- 47EPZ005687 --------------------------------------------------- 47EPZ-5676 ----------------------------------------------------- 47EPZ-6438 ----------------------------------------------------- 47Erastin --------------------------------------------------------- 20Ercalcidiol ---------------------------------------------------- 46Ergosterol ----------------------------------------------------- 49Eribulin Mesylate -------------------------------------------- 12Erlotinib Hydrochloride ---------------------------------2,23Ethisterone --------------------------------------------------- 44Etidronate (Didronel) -------------------------------------- 52Etofenamate -------------------------------------------------- 54Etomoxir ------------------------------------------------------ 46Etoposide (VP-16)------------------------------------------- 11ETP-46464 ---------------------------------------------------- 40Evacetrapib (LY2484595) --------------------------------- 19Everolimus (RAD001) -------------------------------------- 22Evista (Raloxifene Hydrochloride) ----------------------- 44Evodiamine (Isoevodiamine) ----------------------------- 49EX 527 --------------------------------------------------------- 17Exatecan mesylate ------------------------------------------ 11Exemestane --------------------------------------------------- 46Ezatiostat ----------------------------------------------------- 52Ezetimibe (Zetia) ------------------------------------------- 49

FFABP4 Inhibitor --------------------------------------------- 54Fadrozole ----------------------------------------------------- 46Fagomine------------------------------------------------------ 51FAI ------------------------------------------------------------- 54Fasudil HCl (HA-1077) ------------------------------------- 10



Febuxostat (TEI-6720) ------------------------------------- 15Felbamate ----------------------------------------------------- 39Fenoldopam -------------------------------------------------- 42Fenoprofen calcium ----------------------------------------- 52Fenretinide --------------------------------------------------- 52Fenticonazole nitrate --------------------------------------- 52Ferrostatin-1 (ethyl ester) --------------------------------- 20Ferrostatin-1 (Fer-1) --------------------------------------- 20Fesoterodine fumarate (Toviaz) -------------------------- 42Fexofenadine HCl -------------------------------------------- 42FG-4592 ---------------------------------------------------------5FH535 --------------------------------------------------------- 36Fidaxomicin -------------------------------------------------- 53Finasteride------------------------------------------------------5Firategrast (SB 683699) ----------------------------------- 54Fisetin (Fustel) ----------------------------------------------- 49FK 3311 ------------------------------------------------------- 16FK-506 --------------------------------------------------------- 49FK866 ------------------------------------------------------------2Flavopiridol (Alvocidib) --------------------------------------8Flavopiridol HCl -----------------------------------------------8FLI-06 ---------------------------------------------------------- 35Floxuridine --------------------------------------------------- 18Flubendazole (Flutelmium) ------------------------------- 51Flucytosine --------------------------------------------------- 49Fludarabine (Fludara) -------------------------------------- 29Fludarabine (Fludara) ------------------------------------- 16Fludarabine Phosphate (Fludara)------------------------ 29Fludarabine Phosphate (Fludara) ----------------------- 16Flufenamic acid ---------------------------------------------- 40Flumatinib mesylate ---------------------------------------- 54Flumazenil ---------------------------------------------------- 42Flumequine --------------------------------------------------- 11Flunixin meglumine ---------------------------------------- 15Fluocinonide(Vanos) --------------------------------------- 52Fluorouracil (Adrucil) -------------------------------------- 33Flupirtine maleate ------------------------------------------ 16Flurazepam dihydrochloride------------------------------ 53Flurizan ------------------------------------------------------- 35Fluticasone propionate ------------------------------------ 46FM19G11--------------------------------------------------------5FMK ------------------------------------------------------------ 23Folinic acid calcium salt (Leucovorin) ------------------ 51Foretinib (GSK1363089, XL880) ------------------------- 25Formononetin (Formononetol) -------------------------- 49Formoterol ---------------------------------------------------- 41Formoterol hemifumarate --------------------------------- 41Forskolin ------------------------------------------------------ 55Fosamprenavir ----------------------------------------------- 32Fosaprepitant dimeglumine ------------------------------- 51Fosbretabulin disodium (CA4P) -------------------------- 12Fosfluconazole ----------------------------------------------- 54Fosinopril sodium ------------------------------------------- 33Freselestat ---------------------------------------------------- 53FTI 277 -------------------------------------------------------- 47FTY720 (Fingolimod) -------------------------------------- 26Fudosteine ---------------------------------------------------- 49Fulvestrant (Faslodex) ------------------------------------- 44Fumalic acid (Ferulic acid) -------------------------------- 49Furosemide --------------------------------------------------- 42

GGabapentin --------------------------------------------------- 42Gabapentin Hydrochloride -------------------------------- 38Gadodiamide (Omniscan) --------------------------------- 49Galanthamine hydrobromide ----------------------------- 42Gallamine triethiodide ------------------------------------- 42Gambogic acid -------------------------------------------------2Ganciclovir ---------------------------------------------------- 51Ganirelix ------------------------------------------------------ 46GANT 58 ------------------------------------------------------- 35GANT61 ------------------------------------------------------- 35Garcinol ------------------------------------------------------- 47Gastrodin (Gastrodine) ------------------------------------ 49Gatifloxacin -------------------------------------------------- 55GBR-12935 dihydrochloride ------------------------------ 42GDC-0032 ----------------------------------------------------- 22GDC-0068 ----------------------------------------------------- 20GDC-0349 ----------------------------------------------------- 22GDC-0449 (Vismodegib) ----------------------------------- 35GDC-0834 ----------------------------------------------------- 28GDC-0879 -------------------------------------------------------6GDC-0941 ----------------------------------------------------- 20GDC-0973 -------------------------------------------------------6GDC-0980 (RG7422) --------------------------------------- 21GDC0994 -------------------------------------------------------6Gefitinib (Iressa) ------------------------------------------2,23

Geldanamycin ------------------------------------------------ 32Gemcitabine elaidate --------------------------------------- 54Gemcitabine HCl (Gemzar) -------------------------------- 49Gemfibrozil (Lopid) ----------------------------------------- 45Genipin -------------------------------------------------------- 52Geniposide ---------------------------------------------------- 52Genistin (Genistoside)-------------------------------------- 49Gentamycin sulfate (Gentacycol) ------------------------- 50GENZ-644282 ------------------------------------------------ 12Geranylgeranylacetone ------------------------------------- 54Gestodene ----------------------------------------------------- 50GF 109203X -------------------------------------------------- 30GGTI-2418 ---------------------------------------------------- 53Gimeracil ------------------------------------------------------ 15Ginkgolide A -------------------------------------------------- 43Ginkgolide B -------------------------------------------------- 43GKA50 --------------------------------------------------------- 53Glimepiride --------------------------------------------------- 33Gliotoxin ------------------------------------------------------ 31GLPG0634 -------------------------------------------------- 29Glyburide ----------------------------------------------------- 39Glycyrrhetinic acid (Enoxolone) ------------------------- 49Glycyrrhizic acid --------------------------------------------- 50GNE0877 ------------------------------------------------------ 54GNE-7915 ----------------------------------------------------- 54GNF 2 ---------------------------------------------------------- 26GNF 5837 ----------------------------------------------------- 28GNF-5 ---------------------------------------------------------- 26Go 6976 ------------------------------------------------------- 30Gossypol ------------------------------------------------------ 50GR 103691 ---------------------------------------------------- 42Gramine ------------------------------------------------------- 50Granisetron Hydrochloride-------------------------------- 41GS-9620 ------------------------------------------------------- 53GS-9973 ------------------------------------------------------- 27GSK 0660------------------------------------------------------ 45GSK 1210151A (I-BET151) --------------------------- 34,52GSK 2334470------------------------------------------------- 23GSK 269962 -------------------------------------------------- 11GSK 525762A (I-BET-762) -------------------------------- 34GSK J1 ---------------------------------------------------------- 34GSK1059615 ------------------------------------------------- 20GSK1070916 ---------------------------------------------------9GSK1120212 (JTP-74057, Trametinib) -------------------5GSK126 -------------------------------------------------------- 52GSK1292263 ------------------------------------------------- 44GSK1838705A ----------------------------------------------- 26GSK1904529A ----------------------------------------------- 24GSK2126458 ------------------------------------------------- 21GSK221149A (Retosiban) --------------------------------- 53GSK256066 --------------------------------------------------- 14GSK2578215A ----------------------------------------------- 54GSK2606414 ---------------------------------------------------2GSK2636771 ------------------------------------------------- 22GSK2656157 ---------------------------------------------------2GSK2801 ------------------------------------------------------ 34GSK2838232A ----------------------------------------------- 32GSK343 -------------------------------------------------------- 47GSK369796 --------------------------------------------------- 54GSK-3787 ----------------------------------------------------- 45GSK429286A ------------------------------------------------- 10GSK461364 --------------------------------------------------- 10GSK690693 --------------------------------------------------- 20GSK-923295 -------------------------------------------------- 51Guaifenesin (Guaiphenesin) ------------------------------ 50Guanosine ----------------------------------------------------- 52GW 4869 ------------------------------------------------------ 52GW 501516 --------------------------------------------------- 45GW 5074 --------------------------------------------------------7GW 7647 ------------------------------------------------------ 45GW 9662 ------------------------------------------------------ 45GW2580 ------------------------------------------------------- 52GW3965 HCl -------------------------------------------------- 45GW4064 ------------------------------------------------------- 45GW6471 ------------------------------------------------------- 45GW679769 (Casopitant) ----------------------------------- 44GW788388 --------------------------------------------------- 26GW791343 HCl ------------------------------------------ 38,43GW842166X -------------------------------------------------- 44GW843682X -------------------------------------------------- 10GW9508 ------------------------------------------------------- 44GYKI-52466 dihydrochloride ----------------------------- 38Gynostemma Extract --------------------------------------- 50

H

H 89 dihydrochloride --------------------------------------- 30HA-1077 dihydrochloride --------------------------------- 11HA14-1 ----------------------------------------------------------1Halofuginone ------------------------------------------------- 52Haloperidol (Haldol) --------------------------------------- 42Harmane ------------------------------------------------------ 53HC-030031 --------------------------------------------------- 40Hematoxylin (Hydroxybrazilin) -------------------------- 50Heparin sodium --------------------------------------------- 52Hesperadin -----------------------------------------------------9Hesperetin ---------------------------------------------------- 14Hesperidin ---------------------------------------------------- 50Hexestrol ------------------------------------------------------ 44HG-10-102-01------------------------------------------------ 54Hh-Ag1.5 ------------------------------------------------------ 35HhAntag ------------------------------------------------------- 35HIF-C2 -----------------------------------------------------------5HMN-214------------------------------------------------------ 10Honokiol --------------------------------------------------------5Honokiol ------------------------------------------------------ 20Hordenine ---------------------------------------------------- 50HPGDS inhibitor 1 ------------------------------------------- 52HQL-79 -------------------------------------------------------- 12HS-173--------------------------------------------------------- 22HSP-990 ------------------------------------------------------- 33Hydralazine hydrochloride -------------------------------- 50Hydrochlorothiazide ---------------------------------------- 50Hydrocortisone(Cortisol) ---------------------------------- 46Hydroxocobalamin (Vitamin B12a) --------------------- 50Hydroxyflutamide ------------------------------------------- 13Hydroxyurea ------------------------------------------------- 50Hyodeoxycholic acid ---------------------------------------- 50Hypothemycin -------------------------------------------------2

IIbandronate sodium ---------------------------------------- 52Ibodutant (MEN 15596) ----------------------------------- 44Ibudilast (KC-404) ------------------------------------------ 14Ibuprofen (Advil) -------------------------------------------- 15Ibuprofen Lysine (NeoProfen) ---------------------------- 15Ibutamoren (MK-677) -------------------------------------- 53Ibutamoren mesylate (MK-677)-------------------------- 53Ibutilide fumarate ------------------------------------------- 39IC-87114 ------------------------------------------------------ 20Icariin ---------------------------------------------------------- 14I-CBP112 ------------------------------------------------------ 34ICI 118,551 hydrochloride -------------------------------- 41Icilin ------------------------------------------------------------ 40Icotinib ------------------------------------------------------3,24Icotinib Hydrochloride -----------------------------------3,24ID 8 ------------------------------------------------------------- 34Idarubicin HCl------------------------------------------------ 11Idebenone ---------------------------------------------------- 52IDH-C227 ----------------------------------------------------- 55IEM 1754 Dihydrobromide -------------------------------- 38Ifosfamide----------------------------------------------------- 18Iguratimod (T 614) ----------------------------------------- 15IKK-16 --------------------------------------------------------- 29Iloperidone --------------------------------------------------- 50Imatinib (Gleevec) ----------------------------------------4,24Imatinib Mesylate ------------------------------------------- 26IMD 0354 ----------------------------------------------------- 29Imidapril (Tanatril) ----------------------------------------- 33Imipramine Hydrochloride -------------------------------- 54Imiquimod (Aldara) ---------------------------------------- 50Inauhzin ------------------------------------------------------- 17INCB 3284 dimesylate -------------------------------------- 43INCB018424 (Ruxolitinib) -------------------------------- 29INCB024360-------------------------------------------------- 20INCB28060 --------------------------------------------------- 25INCB8761 (PF-4136309) ---------------------------------- 51Indacaterol --------------------------------------------------- 51Indapamide (Lozol) ----------------------------------------- 50Indinavir sulfate --------------------------------------------- 32Indirubin ------------------------------------------------------ 36Indisulam (E7070) ------------------------------------------ 52Indocyanine green ------------------------------------------ 50Indole-3-carbinol -------------------------------------------- 50Indomethacin (Indocid, Indocin) ------------------------ 15INH1 ----------------------------------------------------------- 13INK 128-------------------------------------------------------- 22INNO-206 (Aldoxorubicin) -------------------------------- 18INO-1001 ----------------------------------------------------- 10Inulin ---------------------------------------------------------- 52Iopromide ----------------------------------------------------- 52Ioversol -------------------------------------------------------- 53IOWH032 ----------------------------------------------------- 40

IOX 2 -------------------------------------------------------------5IPI-145 -------------------------------------------------------- 22IPI-493 -------------------------------------------------------- 32IPI-504 (Retaspimycin hydrochloride) ----------------- 32Ipratropium bromide --------------------------------------- 42Irbesartan (Avapro) ---------------------------------------- 11Irinotecan ----------------------------------------------------- 11Irinotecan HCl Trihydrate (Campto) -------------------- 11Irsogladine ---------------------------------------------------- 42Isatoribine monohydrate ---------------------------------- 54Isepamicin ---------------------------------------------------- 51Isoconazole nitrate ------------------------------------------ 50Isoliquiritigenin --------------------------------------------- 50Isoprenaline HCl --------------------------------------------- 41Isotetrandrine------------------------------------------------ 54Isotretinoin --------------------------------------------------- 14Ispinesib (SB-715992) ------------------------------------- 18Isradipine ----------------------------------------------------- 38ISRIB (trans-isomer) -----------------------------------------2Istradefylline (KW-6002) ---------------------------------- 44ITD-1 ----------------------------------------------------------- 30ITF2357 (Givinostat) --------------------------------------- 16Itraconazole (Sporanox) ----------------------------------- 50IU1-------------------------------------------------------------- 48Ivabradine HCl (Procoralan) ------------------------------ 41Ivermectin ---------------------------------------------------- 38IWP-2 ---------------------------------------------------------- 36IWP-L6 -------------------------------------------------------- 36IWR-1-endo -------------------------------------------------- 36Ixabepilone --------------------------------------------------- 12

JJAK Inhibitor I ------------------------------------------------ 29JK 184 ---------------------------------------------------------- 15JNJ 1661010 -------------------------------------------------- 19JNJ 26854165 --------------------------------------------------1JNJ-26481585 ------------------------------------------------ 16JNJ-28312141 ------------------------------------------------ 53JNJ-38877605 ----------------------------------------------- 25JNJ-40411813 ------------------------------------------------ 53JNJ-7706621----------------------------------------------------8JNJ7777120--------------------------------------------------- 42JNK-IN-8 ---------------------------------------------------------6JTC-801 -------------------------------------------------------- 42JTT-705 (Dalcetrapib) -------------------------------------- 19JW 55 ---------------------------------------------------------- 10JWH 133 ------------------------------------------------------- 44JZL184 --------------------------------------------------------- 53

KKaempferol -------------------------------------------------4,24Kartogenin ---------------------------------------------------- 34kb NB 142-70 ------------------------------------------------ 30KB-R7943 mesylate ----------------------------------------- 37Kenpaullone ----------------------------------------------------8Ketanserin (Vulketan Gel) --------------------------------- 41Ketoconazole ------------------------------------------------- 13Ki 20227 ------------------------------------------------------ 28Ki16198 ------------------------------------------------------- 43Ki16425 ------------------------------------------------------- 43Ki8751 -------------------------------------------------------4,24Kinetin --------------------------------------------------------- 50KN-62 ---------------------------------------------------------- 43KN-93 ---------------------------------------------------------- 53Kobe0065 -------------------------------------------------------6Kobe2602 -------------------------------------------------------7KP372-1 ------------------------------------------------------- 20KPT185 -------------------------------------------------------- 38KPT-330 ------------------------------------------------------ 38KRN 633 -----------------------------------------------------3,24KU 0060648 -------------------------------------------------- 22KU-0063794 -------------------------------------------------- 22KU-55933 ----------------------------------------------------- 40KU-60019 ----------------------------------------------------- 40KW-2449 ------------------------------------------------------ 25KW-2478 ------------------------------------------------------ 32KX1-004 ------------------------------------------------------ 27KX2-391 ------------------------------------------------------- 27KY02111 ------------------------------------------------------ 36

LL(+)-Rhamnose Monohydrate ---------------------------- 50L-165,041 ----------------------------------------------------- 45L-741626 ----------------------------------------------------- 42L-779450 -------------------------------------------------------7Lacidipine ----------------------------------------------------- 38Lacosamide --------------------------------------------------- 39Lactacystin ---------------------------------------------------- 31Lafutidine ----------------------------------------------------- 52Lamivudine --------------------------------------------------- 32Lamotrigine -------------------------------------------------- 39Lapatinib (free base) -------------------------------------3,24Lapatinib Ditosylate --------------------------------------2,23Lappaconite Hydrobromide ------------------------------- 50LAQ824 (NVP-LAQ824) ------------------------------------ 16Laquinimod (ABR-215062) ------------------------------- 51Laropiprant (MK0524) ------------------------------------- 43L-Ascorbyl 6-palmitate ------------------------------------- 50laxogenin ------------------------------------------------------ 53LB42708 ------------------------------------------------------ 47LBH589 (Panobinostat) ------------------------------------ 16LCL-161 ---------------------------------------------------------2LDE225 (NVP-LDE225) ------------------------------------ 43LDE225 Diphosphate -------------------------------------- 36LDK-378 ------------------------------------------------------- 26LDN193189 -------------------------------------------------- 26LDN-212854 ------------------------------------------------- 28LDN-57444 --------------------------------------------------- 48Ledipasvir (GS 5885) --------------------------------------- 31LEE011 ----------------------------------------------------------8Leflunomide -------------------------------------------------- 50Lenalidomide (CC-5013) ------------------------------------1Lersivirine (UK-453061) ---------------------------------- 13Letaxaban (TAK-442) --------------------------------------- 18Letrozole ------------------------------------------------------ 46Leucovorin Calcium ----------------------------------------- 50Levomefolate Calcium -------------------------------------- 54Levonorgestrel ----------------------------------------------- 44Levosimendan ----------------------------------------------- 52LGK-974 ------------------------------------------------------- 36L-Glutamine -------------------------------------------------- 50LGX 818 ---------------------------------------------------------7LH 846 --------------------------------------------------------- 55Licofelone ----------------------------------------------------- 15Lidocaine (Alphacaine) ------------------------------------ 39Limonin ------------------------------------------------------- 50Linagliptin (BI-1356) --------------------------------------- 33Lincomycin hydrochloride (U-10149A) ---------------- 18Linezolid (PNU-100766)----------------------------------- 50Linifanib (ABT-869) --------------------------------------3,24Liquiritigenin ------------------------------------------------ 44Lisinopril (Zestril) ------------------------------------------ 33Lithocholic acid ---------------------------------------------- 52Lobucavir ----------------------------------------------------- 53LODENOSINE ------------------------------------------------- 53Lomeguatrib-------------------------------------------------- 47Lomifyllin ----------------------------------------------------- 53Lomustine (CeeNU) ----------------------------------------- 29Lonafarnib (SCH66336) ----------------------------------- 47Lopinavir (ABT-378) ---------------------------------------- 32Loratadine ---------------------------------------------------- 42Lorcaserin ---------------------------------------------------- 41lorcaserin hydrochloride (APD-356) -------------------- 41Lornoxicam (Xefo) ------------------------------------------ 15Loteprednol Etabonate ------------------------------------- 50Lovastatin (Mevacor) --------------------------------------- 19Loxiglumide (CR1505) ------------------------------------- 52LSD1-C76 ----------------------------------------------------- 55L-Thyroxine --------------------------------------------------- 52Lu AE58054 -------------------------------------------------- 41Lubiprostone ------------------------------------------------- 50Luliconazole -------------------------------------------------- 13Lupulone ------------------------------------------------------ 53Lurasidone (SM13496) ------------------------------------ 51Luteolin ------------------------------------------------------- 14LX 1606 ------------------------------------------------------- 15LX 1606 Hippurate ------------------------------------------ 14LX-4211 ------------------------------------------------------- 37LY 2183240 --------------------------------------------------- 38LY 255283 ---------------------------------------------------- 44LY 2874455 -------------------------------------------------3,24LY 379268 ---------------------------------------------------- 43LY2090314 --------------------------------------------------- 36LY2109761 --------------------------------------------------- 30LY2140023 (LY404039) ----------------------------------- 43LY2157299 --------------------------------------------------- 30LY2228820 -----------------------------------------------------6

LY2603618 (IC-83) ---------------------------------------- 7,9LY2608204 --------------------------------------------------- 51LY2784544 --------------------------------------------------- 29LY2811376 --------------------------------------------------- 35LY2835219 -----------------------------------------------------8LY2886721 --------------------------------------------------- 50LY294002 ----------------------------------------------------- 20LY2940680 --------------------------------------------------- 35LY310762 ----------------------------------------------------- 41LY315920 (Varespladib) ----------------------------------- 19LY317615 (Enzastaurin) ----------------------------------- 30LY335979 ----------------------------------------------------- 37LY404187 ----------------------------------------------------- 38LY-411575 ---------------------------------------------------- 35LY450108 ----------------------------------------------------- 38LY500307 ----------------------------------------------------- 44LY573636 (Tasisulam) -----------------------------------1,30

MMagnolol ------------------------------------------------------ 50Malotilate ----------------------------------------------------- 50Manidipine (Manyper) ------------------------------------- 38Manidipine dihydrochloride ------------------------------ 38Maprotiline hydrochloride -------------------------------- 41Maraviroc (UK-427857) ----------------------------------- 43Marbofloxacin ------------------------------------------------ 50Marimastat --------------------------------------------------- 34Masitinib (AB1010) ----------------------------------------- 27MBX-2982 ----------------------------------------------------- 52MC1568 ------------------------------------------------------- 16MCOPPB trihydrochloride --------------------------------- 42MDA 19 -------------------------------------------------------- 44MDL 29951 --------------------------------------------------- 40MDM2 Inhibitor -----------------------------------------------2ME-143 -------------------------------------------------------- 53Mecarbinate -------------------------------------------------- 52Meclizine dihydrochloride--------------------------------- 44Medetomidine hydrochloride ----------------------------- 41Megestrol Acetate ------------------------------------------- 46MEK162 (ARRY-438162) ------------------------------------6Melanotan II -------------------------------------------------- 43Melatonin ----------------------------------------------------- 43Meloxicam (Mobic) ----------------------------------------- 50Memantine hydrochloride --------------------------------- 39Mephenytoin ------------------------------------------------- 14Meprednisone (Betapar) ---------------------------------- 50Mercaptopurine --------------------------------------------- 18Merck SIP Agonist ------------------------------------------- 52Meropenem --------------------------------------------------- 50Mestranol ----------------------------------------------------- 50Metformin hydrochloride ---------------------------------- 50Methacycline HCl (Physiomycine) ----------------------- 50Methazolastone ---------------------------------------------- 50Methoctramine hydrate ------------------------------------ 42Methotrexate (Abitrexate) --------------------------------- 15Methoxsalen (Oxsoralen) ---------------------------------- 13Methoxyresorufin ------------------------------------------- 14Methscopolamine bromide -------------------------------- 42Methyl Hesperidin ------------------------------------------ 50Methyllycaconitine citrate --------------------------------- 39Methylprednisolone ------------------------------------------2Metiamide ---------------------------------------------------- 42Metolazone --------------------------------------------------- 50Metoprolol tartrate ----------------------------------------- 41Metroprolol succinate -------------------------------------- 41Metyrapone --------------------------------------------------- 15Mevastatin ---------------------------------------------------- 19MG-132 -------------------------------------------------------- 31MGCD0103 (Mocetinostat) -------------------------------- 16MGCD-265 --------------------------------------------------- 25MGL-3196----------------------------------------------------- 53MI 2 ------------------------------------------------------------ 33Mianserin hydrochloride ---------------------------------- 41Micafungin ---------------------------------------------------- 53MifaMurtide -------------------------------------------------- 52Mifepristone (Mifeprex) ----------------------------------- 44Miglitol (Glyset) --------------------------------------------- 52Miglustat hydrochloride ----------------------------------- 53Milrinone (Primacor) --------------------------------------- 14Minoxidil (U-10858) ---------------------------------------- 39Mirabegron --------------------------------------------------- 53Mirtazapine --------------------------------------------------- 41Mitiglinide calcium ------------------------------------------ 39Mitotane ------------------------------------------------------- 50Mitoxantrone ------------------------------------------------- 50Mitoxantrone Hydrochloride ----------------------------- 11



Mizolastine --------------------------------------------------- 42Mizoribine ---------------------------------------------------- 18MK 0893 ------------------------------------------------------ 51MK 3207 hydrochloride ------------------------------------ 43MK 886 ------------------------------------------------------- 55MK-0517 (Fosaprepitant) --------------------------------- 52MK-0679 (Verlukast) --------------------------------------- 44MK-0752 ------------------------------------------------------ 35MK-0812 ------------------------------------------------------ 43MK-0974 (Telcagepant) ------------------------------------ 43MK-1439 ------------------------------------------------------ 13MK-1775 --------------------------------------------------------7MK-2048 ------------------------------------------------------ 33MK-2206 dihydrochloride --------------------------------- 20MK-2461 ----------------------------------------------------3,24MK-2894 ------------------------------------------------------ 51MK-3102 ------------------------------------------------------ 53MK-4305 (Suvorexant) ------------------------------------- 44MK-4827 ------------------------------------------------------ 10MK-5108 (VX-689) --------------------------------------------9MK7622 ------------------------------------------------------- 53MK-8245 ------------------------------------------------------ 15MK-8745 --------------------------------------------------------9MKT 077 ------------------------------------------------------ 33ML 161 -------------------------------------------------------- 44ML 171 -------------------------------------------------------- 54ML 7 hydrochloride ----------------------------------------- 52ML-3043 --------------------------------------------------------6ML314 --------------------------------------------------------- 54MLN 0905 ----------------------------------------------------- 10MLN2238 ----------------------------------------------------- 30MLN2480 (BIIB-024) -----------------------------------------7MLN4924 ----------------------------------------------------- 51MLN4924 (HCL Salt)---------------------------------------- 51MLN8054 -------------------------------------------------------9MLN8237 (Alisertib) -----------------------------------------9MLN9708 ----------------------------------------------------- 31MLR 1023 ----------------------------------------------------- 27Moclobemide ------------------------------------------------- 17Moexipril hydrochloride ----------------------------------- 45Mogroside II A2 ---------------------------------------------- 46Mometasone furoate ---------------------------------------- 52Monastrol ----------------------------------------------------- 18Monomethyl auristatin E ---------------------------------- 53Morin hydrate ------------------------------------------------ 50Mosapride citrate ------------------------------------------- 41Motesanib (AMG706)-------------------------------------4,24Motesanib Diphosphate (AMG-706)-------------------4,24Moxalactam Sodium ---------------------------------------- 52Moxifloxacin HCl --------------------------------------------- 11Moxonidine --------------------------------------------------- 33Moxonidine HCl ---------------------------------------------- 52MP470 (MP-470) -------------------------------------------- 25MPC-3100 ----------------------------------------------------- 32MPEP HCl ----------------------------------------------------- 43MPEP hydrochloride ---------------------------------------- 43MRS 2578 ----------------------------------------------------- 43MS-275 (Entinostat) ---------------------------------------- 16MS436 -------------------------------------------------------- 34MSX-122 ------------------------------------------------------- 43Mubritinib (TAK 165) ------------------------------------2,23Mycophenolate mofetil (CellCept) ----------------------- 50Mycophenolic acid ------------------------------------------ 50Myricetin (Cannabiscetin) --------------------------------- 50Myricitrin (Myricitrine) ------------------------------------ 50

NN6022 --------------------------------------------------------- 53NAD 299 hydrochloride (Robalzotan) ------------------ 41NAD+ ----------------------------------------------------------- 52Nadifloxacin -------------------------------------------------- 52Nafamostat mesylate --------------------------------------- 31Naftopidil (Flivas) ------------------------------------------- 41Naftopidil Dihydrochloride -------------------------------- 41Nalbuphine Hydrochloride -------------------------------- 52Nalfurafine hydrochloride --------------------------------- 52Nalmefene hydrochloride --------------------------------- 42Naltrexone HCl ----------------------------------------------- 52Nanchangmycin---------------------------------------------- 50Naproxen sodium ------------------------------------------- 15Naratriptan --------------------------------------------------- 41Naringenin ---------------------------------------------------- 13Naringin (Naringoside) ------------------------------------ 50Naringin Dihydrochalcone -------------------------------- 50Natamycin (Pimaricin) ------------------------------------- 50Nateglinide (Starlix) ---------------------------------------- 39Naxagolide ---------------------------------------------------- 42

NBI-42902 ---------------------------------------------------- 46NBQX ----------------------------------------------------------- 38N-Desmethylclozapine ------------------------------------- 41Nebivolol ----------------------------------------------------- 41Nebivolol HCl ------------------------------------------------- 41Necrostatin-1 ----------------------------------------------1,52Nefiracetam (Translon) --------------------------------------5Nelarabine (Arranon) -------------------------------------- 18Neohesperidin ----------------------------------------------- 50Neohesperidin dihydrochalcone ------------------------ 50Neostigmine bromide (Prostigmin) --------------------- 42Nepafenac ----------------------------------------------------- 50Nepicastat (free base) (SYN-117) ------------------------ 14Nepicastat hydrochloride ---------------------------------- 15Neratinib (HKI-272) --------------------------------------2,23Nevirapine (Viramune) ------------------------------------ 12NF 279 --------------------------------------------------------- 43NHS-Biotin ---------------------------------------------------- 54Nicorandil ----------------------------------------------------- 39Nifedipine ----------------------------------------------------- 38Nifuratel ------------------------------------------------------- 54Nilotinib (AMN-107) --------------------------------------- 26Nilvadipine (ARC029) ------------------------------------- 38Nimesulide --------------------------------------------------- 15Nimodipine --------------------------------------------------- 38Nimorazole --------------------------------------------------- 53Nipradilol ----------------------------------------------------- 52Nitisinone ----------------------------------------------------- 51NKY 80 -------------------------------------------------------- 55NMDA ---------------------------------------------------------- 39NMS-873 ------------------------------------------------------ 48Nobiletin (Hexamethoxyflavone) ------------------------ 50Nocodazole --------------------------------------------------- 12Nolatrexed Dihydrochloride ------------------------------ 53Noradrenaline bitartrate monohydrate ----------------- 52Norfloxacin (Norxacin) ------------------------------------- 50NPI-2358 (Plinabulin) ----------------------------------------5NPS-2143 (SB-262470) ------------------------------------ 38NQDI 1 --------------------------------------------------------- 53NS 309 --------------------------------------------------------- 39NS-398 --------------------------------------------------------- 15NSC 131463 (DAMPA) -------------------------------------- 15NSC 23766 ---------------------------------------------------- 11NSC 319726 ----------------------------------------------------1NSC 405020 -------------------------------------------------- 34NSC-207895 (XI-006) ------------------------------------2,18NSC348884 --------------------------------------------------- 53NSI-189 -------------------------------------------------------- 54NU 6102 ---------------------------------------------------------8NU 9056 ------------------------------------------------------- 47NU7026 ------------------------------------------------------- 23NU-7441 (KU-57788) ---------------------------------- 21,23Nutlin 3a --------------------------------------------------------2Nutlin 3b --------------------------------------------------------2Nutlin-3 ---------------------------------------------------------2NVP-231 ------------------------------------------------------- 53NVP-AAM077 Tetrasodium Hydrate -------------------- 54NVP-ADW742 ------------------------------------------------ 24NVP-AEW541 ------------------------------------------------ 24NVP-BAG956 --------------------------------------------- 21,23NVP-BEP800 ------------------------------------------------- 32NVP-BGT226 ------------------------------------------------- 21NVP-BHG712 ---------------------------------------------------6NVP-BSK805 ------------------------------------------------- 29NVP-BVU972 ------------------------------------------------- 25NXY-059 (Cerovive) ----------------------------------------- 50

OOAC1 ----------------------------------------------------------- 53Obatoclax mesylate (GX15-070) ---------------------------1OC 000459 ---------------------------------------------------- 52Octopamine hydrochloride -------------------------------- 41Octreotide----------------------------------------------------- 44Odanacatib (MK-0822) ------------------------------------- 51Ofloxacin (DL8280) ----------------------------------------- 50OG-L002 ------------------------------------------------------- 34Olanzapine (LY170053) ------------------------------------ 41Olaparib (AZD2281) ---------------------------------------- 10Oleanolic Acid (Caryophyllin) ---------------------------- 50Oligomycin A ------------------------------------------------- 37Olmesartan (RNH6270, CS-088) ------------------------- 33Olmesartan medoxomil ------------------------------------ 33Olopatadine hydrochloride -------------------------------- 42Ombrabulin --------------------------------------------------- 52Omeprazole --------------------------------------------------- 37ON-01910 ----------------------------------------------------- 10Ondansetron (Zofran) -------------------------------------- 39

Ondansetron HCl (GR 38032F) --------------------------- 41ONO 2506 ----------------------------------------------------- 19Opicapone (BIA 9-1067) ----------------------------------- 47Optovin -------------------------------------------------------- 40Org 27569 ---------------------------------------------------- 44Oridonin (Isodonol) ---------------------------------------- 50Orlistat -------------------------------------------------------- 50Orotic acid (6-Carboxyuracil) ----------------------------- 50Orphenadrine citrate --------------------------------------- 42Oseltamivir phosphate (Tamiflu) ------------------------ 51OSI-027 -------------------------------------------------------- 22OSI-420 -----------------------------------------------------2,23OSI-906 -------------------------------------------------------- 24OSI-930 -------------------------------------------------------- 27Ostarine (MK-2866) ---------------------------------------- 45Osthole -------------------------------------------------------- 50OSU-03012 --------------------------------------------------- 23Otamixaban (FXV 673) ------------------------------------- 33OTSSP167 ---------------------------------------------------- 55OTX015 -------------------------------------------------------- 34Ouabain ------------------------------------------------------- 37Oxacillin sodium monohydrate -------------------------- 50Oxaliplatin (Eloxatin) --------------------------------------- 18Oxibendazole ------------------------------------------------- 51Oxybutynin --------------------------------------------------- 42Oxymatrine (Matrine N-oxide) --------------------------- 50Oxymetazoline hydrochloride ---------------------------- 41Oxytetracycline (Terramycin) ---------------------------- 50Ozagrel hydrochloride ------------------------------------- 43Ozagrel(OKY-046) ------------------------------------------- 43Ozarelix-------------------------------------------------------- 43

PP 22077 ------------------------------------------------------- 31P005091 ------------------------------------------------------ 48P005672 HCl ------------------------------------------------ 51P276-00 ---------------------------------------------------------8P505-15 ------------------------------------------------------- 27P7C3 ----------------------------------------------------------- 53P7C3-A20 ----------------------------------------------------- 52PA-824 --------------------------------------------------------- 51PAC-1 --------------------------------------------------------1,30Paclitaxel (Taxol) -------------------------------------------- 12Paeonol (Peonol) -------------------------------------------- 50Palifosfamide ------------------------------------------------- 53Paliperidone -------------------------------------------------- 41Palmatine chloride ------------------------------------------ 50Palomid 529 (P529) ---------------------------------------- 20Palosuran ----------------------------------------------------- 53Palovarotene ------------------------------------------------- 46Pamidronate Disodium ------------------------------------ 50Pamidronic acid --------------------------------------------- 52Panipenem ---------------------------------------------------- 53Pantoprazole (Protonix) ----------------------------------- 37PAP-1 (5-(4-Phenoxybutoxy)psoralen) ----------------- 39Parathyroid Hormone 1-34, Human --------------------- 43Parecoxib ----------------------------------------------------- 16Paroxetine HCl ----------------------------------------------- 52Parthenolide ((-)-Parthenolide) -------------------------- 50Pazopanib Hydrochloride (GW786034) --------------4,24Pazopanib(GW-786034) ----------------------------------- 27PCI-24781 ---------------------------------------------------- 16PCI-32765 ---------------------------------------------------- 27PCI-32765 ---------------------------------------------------- 28PCI-34051 ---------------------------------------------------- 17PD 0332991 HCl -----------------------------------------------8PD 123319 ditrifluoroacetate ---------------------------- 45PD 169316 ------------------------------------------------------6PD0325901 -----------------------------------------------------5PD153035 (HCl salt) --------------------------------------2,23PD173074 --------------------------------------------------3,24PD173955 ---------------------------------------------------- 26PD184352 (CI-1040) ----------------------------------------5PD318088 ------------------------------------------------------5PD98059 --------------------------------------------------------5Pefloxacin mesylate ----------------------------------------- 11Pelitinib (EKB-569) ---------------------------------------2,23Pemetrexed (Alimta) --------------------------------------- 15Pemetrexed disodium -------------------------------------- 52Pentagastrin -------------------------------------------------- 50Peramivir ----------------------------------------------------- 51Perifosine (NSC-639966) ---------------------------------- 20Perindopril Erbumine (Aceon) --------------------------- 33PF 3716556 -------------------------------------------------- 37PF 429242 ---------------------------------------------------- 19PF 431396 --------------------------------------------------- 26PF 4708671 -------------------------------------------------- 23

PF 477736 ------------------------------------------------------7PF 4981517 -------------------------------------------------- 13PF 573228 ---------------------------------------------------- 26PF 670462 ---------------------------------------------------- 52PF-00562271------------------------------------------------- 26PF-03394197 (oclacitinib) -------------------------------- 29PF-03814735---------------------------------------------------9PF-04217903 ------------------------------------------------ 25PF-04447943------------------------------------------------- 14PF-04449913------------------------------------------------- 36PF-04554878------------------------------------------------- 26PF-04691502------------------------------------------------- 20PF-04880594---------------------------------------------------7PF-04929113 (SNX-5422) --------------------------------- 32PF-04971729------------------------------------------------- 39PF-04979064------------------------------------------------- 22PF-06687859------------------------------------------------- 54PF-2341066 (Crizotinib) ---------------------------------- 26PF-2545920 -------------------------------------------------- 14PF299804 ---------------------------------------------------3,23PF-3758309 ----------------------------------------------------2PF-3845 ------------------------------------------------------- 15PF-5274857 -------------------------------------------------- 36PF-562271 ---------------------------------------------------- 26PFI-1 ----------------------------------------------------------- 34PH-797804 -----------------------------------------------------6PHA 408 ------------------------------------------------------- 29PHA-665752-------------------------------------------------- 25PHA-680632----------------------------------------------------9PHA-767491----------------------------------------------------8PHA-793887----------------------------------------------------8PHA-848125 (Milciclib) --------------------------------------8PHCCC --------------------------------------------------------- 43Phenacetin ---------------------------------------------------- 15Phenazepam -------------------------------------------------- 42Phenformin hydrochloride -------------------------------- 40Phenoxybenzamine hydrochloride ---------------------- 41Phenprocoumon --------------------------------------------- 50Phentolamine mesilate ------------------------------------- 41Phenylbutazone --------------------------------------------- 15Phenylephrine hydrochloride ---------------------------- 41Phenytoin (Lepitoin) --------------------------------------- 39Phenytoin sodium (Dilantin) ----------------------------- 39Phloretin (Dihydronaringenin) --------------------------- 50Phlorizin (Phloridzin) -------------------------------------- 50PHT-427 ------------------------------------------------------- 20PI-103 --------------------------------------------------------- 23Piceatannol -------------------------------------------------- 27Picropodophyllin -------------------------------------------- 24Pidotimod ----------------------------------------------------- 52Pifithrin-alpha -------------------------------------------------1Pifithrin-beta ---------------------------------------------------1Pifithrin-u -------------------------------------------------------1PIK-293 -------------------------------------------------------- 20PIK-294 -------------------------------------------------------- 20PIK-75 --------------------------------------------------------- 21PIK-90 --------------------------------------------------------- 21PIK-93 --------------------------------------------------------- 21Pimecrolimus ------------------------------------------------ 50Pimobendan (Vetmedin) ----------------------------------- 14Pinaverium Bromide --------------------------------------- 38Pindolol ------------------------------------------------------- 41Pioglitazone (Actos) ---------------------------------------- 52Piperine (1-Piperoylpiperidine) ------------------------- 50Pirarubicin ---------------------------------------------------- 11pirinixic acid (WY 14643) --------------------------------- 45Pirodavir ------------------------------------------------------ 53Piroxicam (Feldene) ---------------------------------------- 15Pitavastatin calcium (Livalo) ------------------------------ 19Pizotifen malate --------------------------------------------- 50PJ 34 hydrochloride ----------------------------------------- 10PKC 412 -----------------------------------------------------3,24PKI-402-------------------------------------------------------- 21PKI-587-------------------------------------------------------- 22Plerixafor 8HCl (DB06809) ------------------------------- 51Pluripotin (SC-1) ----------------------------------------------2PluriSln 1------------------------------------------------------ 53PLX4032 (Vemurafenib) -------------------------------------6PLX-4720--------------------------------------------------------6Pneumocandin B0 ------------------------------------------- 51PNU 282987 -------------------------------------------------- 39PNU-120596 ------------------------------------------------- 42Podophyllotoxin ----------------------------------------- 11,12Polydatin (Piceid) ------------------------------------------- 50Pomalidomide (CC-4047) -----------------------------------1Posaconazole ------------------------------------------------- 50PP1 ------------------------------------------------------------- 27PP1 Analog II, 1NM-PP1 ----------------------------------- 27PP121 ---------------------------------------------------------- 21PP2 ------------------------------------------------------------- 27PP242 ---------------------------------------------------------- 22

PPQ-102 ------------------------------------------------------- 40PQ 401 --------------------------------------------------------- 24PR-171 (Carfilzomib) --------------------------------------- 31PR-619 --------------------------------------------------------- 48Pralatrexate -------------------------------------------------- 31Pramipexole 2HCl monohyrate --------------------------- 42Pramipexole dihydrochloride ----------------------------- 42Pramiracetam ------------------------------------------------ 52Pranlukast (ONO 1078) ------------------------------------ 44Pranoprofen -------------------------------------------------- 51Prasugrel (Effient) ------------------------------------------ 38Pravadoline (WIN 48098) --------------------------------- 15Pravastatin sodium ----------------------------------------- 19Praziquantel (Biltricide) ----------------------------------- 50Prazosin HCl -------------------------------------------------- 41Prednisolone acetate (Omnipred) ----------------------- 52Prednisone (Adasone) ------------------------------------- 50Pregnenolone ------------------------------------------------ 44Prilocaine ----------------------------------------------------- 50PRIMA-1 ---------------------------------------------------------1Primidone (Mysoline) -------------------------------------- 42Pristinamycin ------------------------------------------------ 52Probucol------------------------------------------------------- 52Procaterol HCl ----------------------------------------------- 41Prochloraz manganese ------------------------------------- 53Proparacaine HCl -------------------------------------------- 39Prostaglandin E1 (PGE1) ---------------------------------- 43PRT062607 HCL --------------------------------------------- 27Prucalopride ------------------------------------------------- 41Prulifloxacin (Pruvel) --------------------------------------- 51PRX-08066 ---------------------------------------------------- 41PS 48 ----------------------------------------------------------- 23PSC-833 ------------------------------------------------------- 37PSI -------------------------------------------------------------- 31PSI-6130 ------------------------------------------------------ 31PSI-6206 ------------------------------------------------------ 31PSI-7977 ------------------------------------------------------ 31PTC124 (Ataluren) ------------------------------------------ 50PTC124 (Ataluren) ----------------------------------------- 39PTC-209 ------------------------------------------------------- 54PTZ-343 ------------------------------------------------------- 54PU 02 ---------------------------------------------------------- 41Puerarin (Kakonein) ---------------------------------------- 41PU-H71 -------------------------------------------------------- 32Purmorphamine --------------------------------------------- 36Purvalanol B ----------------------------------------------------8PX 12 ----------------------------------------------------------- 54PX-866 --------------------------------------------------------- 21PYR-41 --------------------------------------------------------- 48Pyridoxine HCl ----------------------------------------------- 52Pyrintegrin --------------------------------------------------- 53Pyronaridine Tetraphosphate ---------------------------- 52Pyroxamide (NSC 696085) -------------------------------- 16Pyrroloquinoline quinone --------------------------------- 53

QQNZ ----------------------------------------------------------1,29QS 11 ----------------------------------------------------------- 43Quarfloxin (CX-3543) --------------------------------------- 52Quercetin (Sophoretin) ------------------------------------ 21Quercetin dihydrate (Sophoretin) ----------------------- 21Quetiapine fumarate ---------------------------------------- 50Quinacrine 2HCl --------------------------------------------- 53Quinapril hydrochloride ----------------------------------- 45QX 314 chloride---------------------------------------------- 39

RR1530 ---------------------------------------------------------- 53R406 ----------------------------------------------------------- 27R406 (freebase) --------------------------------------------- 27R428 ----------------------------------------------------------- 28R547 -------------------------------------------------------------8R788 (Fostamatinib) --------------------------------------- 27R935788 ------------------------------------------------------ 27Racecadotril (Acetorphan) -------------------------------- 50Radicicol ------------------------------------------------------ 33RAF265 (CHIR-265) ------------------------------------------7Raf265 derivative ---------------------------------------------7Raltegravir (MK-0518) ------------------------------------- 33Raltitrexed (Tomudex) ------------------------------------- 12Ramelteon (TAK-375) -------------------------------------- 50Ranolazine ---------------------------------------------------- 15

Rapamycin (Sirolimus) ------------------------------------- 22Rasagiline ----------------------------------------------------- 51Rasagiline mesylate ----------------------------------------- 17Ravuconazole ------------------------------------------------ 53Razaxaban ---------------------------------------------------- 18RC-3095 ------------------------------------------------------- 53Reboxetine mesylate ---------------------------------------- 38Refametinib (RDEA-119, BAY 86-9766) ------------------6Regorafenib (BAY 73-4506) ------------------------------- 27Repaglinide --------------------------------------------------- 39Reparixin ------------------------------------------------------ 43RepSox (SJN 2511) ------------------------------------------ 30Resibufogenin ------------------------------------------------ 37Resminostat ------------------------------------------------- 17Resveratrol --------------------------------------------------- 17Retapamulin (SB-275833) -------------------------------- 51Retigabine (Ezogabine) ------------------------------------ 39Reversine -------------------------------------------------------9RGFP966 ------------------------------------------------------ 17Rhein (Monorhein) ----------------------------------------- 50Rheochrysidin (Physcione) ------------------------------- 50RI-1 ------------------------------------------------------------- 53Ribitol (Adonitol) ------------------------------------------- 51Rifabutin ------------------------------------------------------ 50Rifampin ------------------------------------------------------ 44Rifapentine (Priftin) ---------------------------------------- 50Rifaximin (Xifaxan) ----------------------------------------- 50Rilmenidine -------------------------------------------------- 41Rilpivirine (R 278474, TMC 278) ------------------------ 51Riluzole (Rilutek) ------------------------------------------- 39Rimantadine (Flumadine) --------------------------------- 51Rimonabant (SR141716) ---------------------------------- 44Riociguat (BAY 63-2521) ---------------------------------- 54Risedronate sodium ---------------------------------------- 50Risedronic acid (Actonel) ---------------------------------- 52Risperidone (Risperdal) ----------------------------------- 41RITA (NSC 652287) -------------------------------------------1Ritonavir ------------------------------------------------------ 32Rivaroxaban (Xarelto) -------------------------------------- 18Rivaroxaban Diol -------------------------------------------- 18Rivastigmine tartrate --------------------------------------- 42RKI-1447 ------------------------------------------------------ 11Ro 61-8048 --------------------------------------------------- 15Ro 90-7501 --------------------------------------------------- 14RO3280 -------------------------------------------------------- 10RO4927350 -----------------------------------------------------5RO4929097 --------------------------------------------------- 35RO4987655 -----------------------------------------------------6RO5126766 -----------------------------------------------------6Rocuronium bromide --------------------------------------- 42Rofecoxib (Vioxx) ------------------------------------------- 15Roflumilast --------------------------------------------------- 14Rolipram ------------------------------------------------------ 14Romidepsin (FK228 ,Depsipeptide) --------------------- 17Ropinirole ----------------------------------------------------- 42Ropinirole HCl ----------------------------------------------- 42Roscovitine (Seliciclib) ---------------------------------------8Rosiglitazone (BRL-49653) ------------------------------- 45Rosiglitazone maleate -------------------------------------- 45Rostafuroxin (PST-2238) ---------------------------------- 37Rosuvastatin -------------------------------------------------- 45Rosuvastatin calcium (Crestor) -------------------------- 45Rotigotine ----------------------------------------------------- 42Rotigotine hydrochloride ---------------------------------- 42Rotundine ----------------------------------------------------- 42Roxatidine acetate hydrochloride ------------------------ 42RPI-1 ----------------------------------------------------------- 54RS-127445 ---------------------------------------------------- 41RU 24969 hemisuccinate ---------------------------------- 41Ruboxistaurin (LY333531) -------------------------------- 30Rupatadine --------------------------------------------------- 42Rupatadine Fumarate -------------------------------------- 42Rutaecarpine (Rutecarpine) ------------------------------ 50Rutin (Rutoside) --------------------------------------------- 50

SS/GSK1349572 ---------------------------------------------- 33S1RA ----------------------------------------------------------- 55S3I-201 (NSC 74859) --------------------------------------- 29Sabutoclax ------------------------------------------------------1Safinamide ---------------------------------------------------- 17Safinamide Mesylate (FCE28073) ----------------------- 17Salbutamol sulfate (Albuterol) --------------------------- 41Salicin (Salicoside, Salicine) ------------------------------- 50Salidroside (Rhodioloside) -------------------------------- 50Salinomycin (Procoxacin) --------------------------------- 50



Salmefamol --------------------------------------------------- 51Salmeterol ---------------------------------------------------- 41Salubrinal ----------------------------------------------------- 53SANT-1 --------------------------------------------------------- 35Sapacitabine (CYC682) ------------------------------------- 53Saquinavir ---------------------------------------------------- 32SAR131675 -------------------------------------------------4,24Saracatinib (AZD0530)------------------------------------- 27Sarafloxacin hydrochloride -------------------------------- 51Saxagliptin (BMS-477118) -------------------------------- 33SB 202190 ------------------------------------------------------6SB 203580 ------------------------------------------------------6SB 216763 ---------------------------------------------------- 36SB 239063 ------------------------------------------------------6SB 334867 ---------------------------------------------------- 44SB 415286 --------------------------------------------------- 36SB 431542 ---------------------------------------------------- 26SB 525334 ---------------------------------------------------- 30SB 743921 ---------------------------------------------------- 18SB1317 (TG-02) ---------------------------------------8,25,29SB269970 HCl------------------------------------------------ 41SB-277011 ---------------------------------------------------- 42SB-408124 ---------------------------------------------------- 43SB-505124 ---------------------------------------------------- 30SB590885 -------------------------------------------------------7SB-649868 ---------------------------------------------------- 44SB-705498 ---------------------------------------------------- 36SB939 ---------------------------------------------------------- 16SC-26196 ------------------------------------------------------ 19SC-514 --------------------------------------------------------- 29SCH 442416 -------------------------------------------------- 44SCH 54292 ---------------------------------------------------- 54SCH 900776 (MK-8776) -------------------------------------7SCH-527123 -------------------------------------------------- 43SCH772984 -----------------------------------------------------6SCH900776 -----------------------------------------------------7Schisandrin B ------------------------------------------------ 52Sclareol -------------------------------------------------------- 50Sclareolide (Norambreinolide) --------------------------- 51Scriptaid------------------------------------------------------- 17SDZ 205-557 HCl -------------------------------------------- 41SDZ 220-581 ------------------------------------------------- 39Selamectin ---------------------------------------------------- 38Semagacestat (LY450139) --------------------------------- 35Sesamin (Fagarol) ------------------------------------------- 51Setrobuvir (ANA-598) -------------------------------------- 31SF1126 -------------------------------------------------------- 22SF1670 -------------------------------------------------------- 54SGC 0946 ------------------------------------------------------ 47SGC-CBP30 --------------------------------------------------- 34SGI-110 -------------------------------------------------------- 19SGI-1776 (free base) ---------------------------------------- 29SGX-523 ------------------------------------------------------- 25Shikimic acid (Shikimate) --------------------------------- 51SIB 1757 ------------------------------------------------------ 43SIB 1893 ------------------------------------------------------ 43Silibinin (Silybin) -------------------------------------------- 51Silymarin (Silybin B)---------------------------------------- 51Sinomenine (Cucoline) ------------------------------------- 51Siramesine ---------------------------------------------------- 53Siramesine Hydrochloride --------------------------------- 52Sitagliptin phosphate monohydrate -------------------- 33Sitaxsentan sodium (TBC-11251) ----------------------- 43Skepinone-L ---------------------------------------------------6SKF 89976A hydrochloride ------------------------------- 42SKLB1002 ---------------------------------------------------4,24SKLB610 ----------------------------------------------------4,24SL 0101-1 ----------------------------------------------------- 23SL251188 ----------------------------------------------------- 17SMER-3 -------------------------------------------------------- 48SMI-4a --------------------------------------------------------- 29SN 38 ----------------------------------------------------------- 11SNS-032 (BMS-387032) -------------------------------------8SNS-314 ---------------------------------------------------------9SNT-207707 -------------------------------------------------- 53SNT-207858 -------------------------------------------------- 53SNX-2112 ----------------------------------------------------- 32Sodium Danshensu ----------------------------------------- 13Sodium orthovanadate ------------------------------------- 51Solifenacin succinate --------------------------------------- 42Sophocarpine ------------------------------------------------ 51Sorafenib (Nexavar) ------------------------------------------6Sotrastaurin (AEB071) ------------------------------------- 30SP-420 --------------------------------------------------------- 53SP600125 -------------------------------------------------------6Spectinomycin HCl ------------------------------------------ 51SR 144528 ---------------------------------------------------- 46SR 3677 dihydrochloride ---------------------------------- 11SR 48692 ------------------------------------------------------ 44SRPIN340 ----------------------------------------------------- 53SRT1720 ------------------------------------------------------ 17

SRT3109 ------------------------------------------------------ 43SRT3190 ------------------------------------------------------ 43ST 101(ZSET1446) ------------------------------------------ 54Staurosporine ------------------------------------------------ 51StemRegenin 1 (SR1) --------------------------------------- 53STF 118804 --------------------------------------------------- 54STF-62247 ---------------------------------------------------- 51Stigmasterol (Stigmasterin) ------------------------------- 51Stiripentol ---------------------------------------------------- 52Streptozotocin (Zanosar) ---------------------------------- 51Strontium ranelate (Protelos) ---------------------------- 52SU 5416 (Semaxinib) -------------------------------------4,24SU11274 ------------------------------------------------------ 25SU14813 ----------------------------------------------------4,24SU-5402 -----------------------------------------------------3,24Sulbactam ----------------------------------------------------- 51Sulindac (Clinoril) ------------------------------------------ 15Sunitinib Malate -------------------------------------------3,24Suplatast tosilate -------------------------------------------- 29SVT-40776 (Tarafenacin) ---------------------------------- 42SYN-115 ------------------------------------------------------- 44Synephrine (Oxedrine) ------------------------------------- 41

TT0901317 ----------------------------------------------------- 46T-705 (Favipiravir) ------------------------------------------ 12TAE684 -------------------------------------------------------- 25Tafenoquine -------------------------------------------------- 53TAK-285 -----------------------------------------------------3,23TAK-438 ------------------------------------------------------- 39TAK-441 ------------------------------------------------------- 35TAK-632 ---------------------------------------------------------7TAK-700 (Orteronel) --------------------------------------- 13TAK-700 (Orteronel) --------------------------------------- 18TAK-700 (salt) ----------------------------------------------- 19TAK-715 ---------------------------------------------------------6TAK-733 ---------------------------------------------------------5TAK-875 ------------------------------------------------------- 44TAK-901 ---------------------------------------------------------9TAK-960 ------------------------------------------------------- 10Talarozole ----------------------------------------------------- 46Talmapimod (SCIO-469) -------------------------------------6Talniflumate -------------------------------------------------- 39TAME ---------------------------------------------------------- 12Tamoxifen Citrate ------------------------------------------- 44Tamsulosin --------------------------------------------------- 41Tamsulosin hydrochloride --------------------------------- 44Tandospirone ------------------------------------------------ 41Tandutinib (MLN518) -------------------------------------- 25Tangeretin (Tangeritin) ------------------------------------ 51Tanshinone I-------------------------------------------------- 51Tanshinone IIA (Tanshinone B) -------------------------- 51TAPI-1 --------------------------------------------------------- 54Tariquidar (XR9576) --------------------------------------- 38Tasosartan ---------------------------------------------------- 43Taurine -------------------------------------------------------- 51Taxifolin ----------------------------------------------------4,24Tazarotene ---------------------------------------------------- 51TC-DAPK6 ----------------------------------------------------- 54TCN 201 ------------------------------------------------------- 39TCS 1102 ------------------------------------------------------ 44TCS 359-------------------------------------------------------- 25TCS ERK 11e (VX-11e) ---------------------------------------6TCS JNK 5a ------------------------------------------------------6TCS PIM-1 4a ------------------------------------------------- 29TDZD-8 ------------------------------------------------------- 36Tedizolid (TR-701) ------------------------------------------ 51Tegafur -------------------------------------------------------- 49Tegaserod maleate ------------------------------------------ 41Teglarinad chloride ----------------------------------------- 28Tegobuvir (GS-9190) --------------------------------------- 31Telaprevir (VX-950)----------------------------------------- 31Telatinib (BAY 57-9352) ---------------------------------3,24Telavancin ---------------------------------------------------- 53Telithromycin (Ketek) -------------------------------------- 52Telmisartan --------------------------------------------------- 43Temocapril ---------------------------------------------------- 45TEMPOL ------------------------------------------------------- 53Temsirolimus (Torisel) ------------------------------------- 22Tenofovir (Viread) ------------------------------------------ 12Tenofovir (Viread) ------------------------------------------ 12Tenofovir Disoproxil Fumarate --------------------------- 10Tenofovir Disoproxil Fumarate -------------------------- 13Tenovin-1 -------------------------------------------------------1Tenovin-3 -------------------------------------------------------1Tenovin-6 -------------------------------------------------------1

Tenoxicam ---------------------------------------------------- 51Tepoxalin ------------------------------------------------------ 53Terazosin hydrochloride ----------------------------------- 41Terbinafine hydrochloride (Lamisil) -------------------- 51Tetrahydropapaverine hydrochloride ------------------- 51Tetrahydrozoline Hydrochloride ------------------------- 41Tetrandrine (Fanchinine) ---------------------------------- 38TG 100572 ---------------------------------------------------- 54TG 100713 ---------------------------------------------------- 22TG 100801 ---------------------------------------------------- 54TG003------------------------------------------------------------8TG100-115---------------------------------------------------- 21TG101209----------------------------------------------------- 29TG-101348---------------------------------------------------- 29TGR5-Receptor-Agonist ------------------------------------ 54TGX-221 ------------------------------------------------------- 21TH-302 -------------------------------------------------------- 13Theobromine (3,7-Dimethylxanthine) ------------------ 51Thiamet G ----------------------------------------------------- 53Thiazovivin --------------------------------------------------- 10Thioridazine hydrochloride ------------------------------- 42Thiostrepton ------------------------------------------------- 18THIQ ----------------------------------------------------------- 43Tianeptine sodium ------------------------------------------ 41Ticagrelor (AZD6140) -------------------------------------- 43Ticlopidine hydrochloride --------------------------------- 43Tideglusib ----------------------------------------------------- 36Tie2 kinase inhibitor --------------------------------------- 27Tigecycline ---------------------------------------------------- 51Tioconazole --------------------------------------------------- 51Tioxolone ----------------------------------------------------- 54Tipifarnib (Zarnestra) ----------------------------------------2Tipiracil ------------------------------------------------------- 53Tirapazamine ------------------------------------------------ 53Tirasemtiv ---------------------------------------------------- 52Tirofiban Hydrochloride Hydrate ------------------------ 54Tivozanib (AV-951) ---------------------------------------4,24TMC353121 -------------------------------------------------- 51TMPA ---------------------------------------------------------- 52TMS ------------------------------------------------------------ 13Toceranib (PHA 291639, SU 11654) ------------------3,24Tofogliflozin -------------------------------------------------- 37TOK-001 (Galeterone) -------------------------------------- 13TOK-001 (Galeterone) ------------------------------------- 18Tolfenamic acid ---------------------------------------------- 15Toll-Like Receptor 7 Ligand II ---------------------------- 54Tolnaftate ----------------------------------------------------- 51Tolrestat ------------------------------------------------------ 55Tolterodine tartrate (Detrol LA) ------------------------- 42Tolvaptan ----------------------------------------------------- 43Tonabersat (SB-220453) ---------------------------------- 51Topotecan HCl (Hycamtin) -------------------------------- 11Torcetrapib (CP-529414) ---------------------------------- 19Torin 1 --------------------------------------------------------- 23Torin 2 --------------------------------------------------------- 23TP-434 --------------------------------------------------------- 54TP808 ---------------------------------------------------------- 53TPCA-1 -------------------------------------------------------- 29TPEN ---------------------------------------------------------- 54TPT-260 (Dihydrochloride) -----------------------------4,24TRAM-34 ------------------------------------------------------ 39Tranilast (SB 252218) -------------------------------------- 51Tranylcypromine hydrochloride ------------------------- 34Trazodone hydrochloride ---------------------------------- 41Trelagliptin Succinate (SYR-472) ------------------------ 33Treprostinil --------------------------------------------------- 54Trichostatin-A (TSA)---------------------------------------- 16Triciribine ---------------------------------------------------- 20Triciribine phosphate (NSC-280594) ------------------- 20Trimebutine -------------------------------------------------- 42Trimetrexate ------------------------------------------------- 15Trimipramine ------------------------------------------------ 53Triphendiol (NV-196) -------------------------------------- 53Troglitazone -------------------------------------------------- 45Tropanserin -------------------------------------------------- 41Tropicamide -------------------------------------------------- 42Tropisetron (ICS 205930) --------------------------------- 41Troxacitabine (SGX-145) ----------------------------------- 51Troxerutin ---------------------------------------------------- 51TSU-68 (SU6668) -----------------------------------------4,24TTNPB --------------------------------------------------------- 53Tubacin -------------------------------------------------------- 17Tubastatin A HCl--------------------------------------------- 17TW-37 -----------------------------------------------------------1TWS119 ------------------------------------------------------- 36Tyrphostin AG 183 ----------------------------------------3,24Tyrphostin AG 879 ----------------------------------------2,23

UU 95666E ----------------------------------------------------- 42U0126-EtOH ----------------------------------------------------5UCPH 101 ----------------------------------------------------- 38UK-383367 --------------------------------------------------- 28UNC 0638 ----------------------------------------------------- 47UNC 669 ------------------------------------------------------- 34UNC0321 ------------------------------------------------------ 47UNC0631 ------------------------------------------------------ 53UNC0646 ------------------------------------------------------ 47UNC1215 ------------------------------------------------------ 34UPF 1069 ----------------------------------------------------- 10UR-144 -------------------------------------------------------- 51Urapidil hydrochloride ------------------------------------- 41URB597 ------------------------------------------------------- 19URB754 ------------------------------------------------------- 51Ursolic acid (Malol) ----------------------------------------- 51

VValdecoxib ---------------------------------------------------- 16Vancomycin --------------------------------------------------- 53Vandetanib (ZD6474) ------------------------------------4,24Vanillylacetone ----------------------------------------------- 51Vanoxerine 2HCl (GBR-12909) --------------------------- 50Vardenafil ----------------------------------------------------- 14Varenicline ---------------------------------------------------- 38Vatalanib (PTK787) 2HCl ---------------------------------- 24Vatalanib (PTK787) 2HCl Base ----------------------------4VCH-916 ------------------------------------------------------- 31VE-821 --------------------------------------------------------- 40VE-822 --------------------------------------------------------- 40VER 155008 -------------------------------------------------- 33VER-50589 --------------------------------------------------- 33Verteporfin --------------------------------------------------- 52VGX-1027 ----------------------------------------------------- 29Vicriviroc Malate -------------------------------------------- 43Vilazodone ---------------------------------------------------- 41Vildagliptin --------------------------------------------------- 33Vinblastine---------------------------------------------------- 12Vincristine sulfate ------------------------------------------- 12Vinflunine Tartrate ------------------------------------------ 12Vinorelbine (Navelbine) -------------------------------------6Vinpocetine --------------------------------------------------- 39Vofopitant (GR 205171) ----------------------------------- 53Vorapaxar (SCH 530348) ---------------------------------- 53Voriconazole (Vfend) --------------------------------------- 13Vorinostat (SAHA) ------------------------------------------ 17Vortioxetine hydrobromide ------------------------------- 41VRT752271 ----------------------------------------------------6VS-5584 ------------------------------------------------------- 22VTX-2337 ----------------------------------------------------- 54VU 0357121 -------------------------------------------------- 43VU 0361737 -------------------------------------------------- 43VU 0364439 -------------------------------------------------- 43VX-222 --------------------------------------------------------- 31VX-661 --------------------------------------------------------- 40VX-680 (MK-0457, Tozasertib) -----------------------------9VX-702 -----------------------------------------------------------6VX-745 -----------------------------------------------------------6VX-765 -------------------------------------------------------1,30VX-770 (Ivacaftor) ------------------------------------------ 39VX-809 ----------------------------------------------------- 40,51

WWAY-100635-------------------------------------------------- 41WAY-362450-------------------------------------------------- 45WAY-600------------------------------------------------------- 22WF 11899A --------------------------------------------------- 52WHI-P 154 ---------------------------------------------------- 29WIN 55,212-2 mesylate ------------------------------------ 44WK23 ---------------------------------------------------------- 54Wnt-C59 ------------------------------------------------------- 36Wortmannin -------------------------------------------------- 21WP1066 ------------------------------------------------------- 29WP1130 ( Degrasyn ) --------------------------------------- 26WW298 -------------------------------------------------------- 54WYE-125132 (WYE-132) ---------------------------------- 22WYE-354 ------------------------------------------------------ 22WYE-687 ------------------------------------------------------ 22

WZ3146 -----------------------------------------------------3,23WZ4002 -----------------------------------------------------3,23WZ8040 -----------------------------------------------------3,23WZ811 --------------------------------------------------------- 43

XXanthone (Genicide) ---------------------------------------- 51XAV 939 ------------------------------------------------------- 35XCT 790 ------------------------------------------------------- 44XEN445 ------------------------------------------------------- 53XL019 ---------------------------------------------------------- 29XL147 ---------------------------------------------------------- 21XL184 free base (Cabozantinib) --------------------4,24,28XL-228 --------------------------------------------------------- 24XL388 ---------------------------------------------------------- 23XL647 --------------------------------------------------------3,23XL765 ---------------------------------------------------------- 21XL-888 --------------------------------------------------------- 32

YY-27632 dihydrochloride ---------------------------------- 10Y320 ----------------------------------------------------------- 52Y-33075 ------------------------------------------------------- 11YC-1 ------------------------------------------------------------ 54YH249 --------------------------------------------------------- 54YIL 781 -------------------------------------------------------- 43YM155 -----------------------------------------------------------1YM201636 ---------------------------------------------------- 21YO-01027 ----------------------------------------------------- 35Yohimbine hydrochloride (Antagonil) ------------------ 51

ZZanamivir ----------------------------------------------------- 51Zardaverine --------------------------------------------------- 14Zaurategrast (CDP323) ------------------------------------ 51ZCL-278 ---------------------------------------------------------8Zearalenone -------------------------------------------------- 44Zibotentan (ZD4054) --------------------------------------- 43ZLN005 -------------------------------------------------------- 54ZM 306416 hydrochloride-------------------------------4,24ZM 323881 hydrochloride-------------------------------4,24ZM 336372 -----------------------------------------------------7ZM-447439 -----------------------------------------------------9Zofenopril calcium ------------------------------------------ 33Zoledronic Acid ---------------------------------------------- 30Zotarolimus -------------------------------------------------- 23ZSTK474 ------------------------------------------------------ 21Z-VAD-FMK -------------------------------------------------1,30

Othersβ-Sitosterol --------------------------------------------------- 51(-)-Blebbistcitin ---------------------------------------------- 37(-)-Catechin gallate----------------------------------------4,24(-)-Epigallocatechin gallate ------------------------------- 48(-)-Gallocatechin -------------------------------------------- 31(-)-Huperzine A ---------------------------------------------- 38(+)-Bicuculline ----------------------------------------------- 42(+)-JQ1 --------------------------------------------------------- 34(Glp1)-Apelin-13 -------------------------------------------- 53(R)-Bicalutamide -------------------------------------------- 45(S)-(+)-Flurbiprofen ---------------------------------------- 15(S)-10-Hydroxycamptothecin----------------------------- 11(S)-Reticuline ------------------------------------------------ 5410058-F4 ----------------------------------------------------- 541400W Dihydrochloride ----------------------------------- 1217 alpha-propionate ---------------------------------------- 4517-AAG (KOS953) ------------------------------------------- 3217-DMAG HCl (Alvespimycin) ---------------------------- 321-NA-PP1------------------------------------------------------ 272-Hydroxysaclofen ------------------------------------------ 422-Methoxyestradiol -------------------------------------------53-Cyano-7-ethoxycoumarin ------------------------------- 133-Indolebutyric acid ---------------------------------------- 483-Methyladenine -------------------------------------------- 214-Demethylepipodophyllotoxin -------------------------- 48

4-Epi Minocycline ------------------------------------------- 534-epi-Chlortetracycline Hydrochloride ----------------- 344-Methylumbelliferone (4-MU) -------------------------- 485-Aminolevulinic acid hydrochloride ------------------- 485-BrdU --------------------------------------------------------- 545-hydroxymethyl tolterodine ----------------------------- 425-hydroxytryptophan (5-HTP) --------------------------- 417-Aminocephalosporanic acid ---------------------------- 48

Innovation through Bioscience · Adooq Bioscience Kinase Inhibitors Catalog 2014-2015 Adooq...

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Transcript of Innovation through Bioscience · Adooq Bioscience Kinase Inhibitors Catalog 2014-2015 Adooq...