INNOVATION IN LOCAL DRUG DELIVERY · Adriele Prina-Mello, University Trinity College, Dublin,...

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18 th School for Doctorate in Pharmaceutical Technology INNOVATION IN LOCAL DRUG DELIVERY 25-27 September 2018 Como Abstract: Some diseases of particular anatomic districts are not adequately treated by systemic drug administration, mainly because of the difficulty to reach the district itself. Local drug delivery methods are currently developed to efficiently pathologies of inner ear, eyes, SNC, and to target drugs to tumors. A wide range of delivery systems or devices for local drug delivery have been developed and are currently under clinic evaluation. The school will cover the main topics related to Local Drug Delivery, including issues for designing delivery systems, characterization tools, in vitro/in vivo application and regulatory aspects. The program will include lessons from speakers with different expertise as well as oral presentation by PhD students, in order to provide a comprehensive view on the topic. School Directors: Prof. Bice Conti, Università degli Studi di Pavia, Dipartimento di Scienze del Farmaco, [email protected] Prof. Paola Minghetti, Università degli Studi di Milano, Dipartimento di Scienze Farmaceutiche, [email protected] Scientific Committee: Prof.ssa A.M. Fadda Università degli Studi di Cagliari Prof. P. Caliceti Università degli Studi di Padova Prof. M. Carafa Università di Roma La Sapienza Prof. G. De Rosa Università degli Studi di Napoli Federico II Prof. M. Fresta Università Magna Grecia di Catanzaro Prof. P. Minghetti Università degli Studi di Milano Prof. G. Puglisi Università degli Studi di Catania Organizing Committee Bice Conti, Ida Genta, Rossella Dorati - Università degli Studi di Pavia Paola Minghetti, Francesco Cilurzo, Francesca Selmin, Lucia Zema - Università degli Studi di Milano Segretariat Fondazione Volta

Transcript of INNOVATION IN LOCAL DRUG DELIVERY · Adriele Prina-Mello, University Trinity College, Dublin,...

Page 1: INNOVATION IN LOCAL DRUG DELIVERY · Adriele Prina-Mello, University Trinity College, Dublin, Ireland 12:30 Implantable anti-cancer drug delivery systems David Stepensky, Ben-Gurion

18thSchoolforDoctorateinPharmaceuticalTechnology

INNOVATIONINLOCALDRUGDELIVERY

25-27September2018Como

Abstract:Somediseasesofparticularanatomicdistrictsarenotadequatelytreatedbysystemicdrugadministration,mainlybecauseofthedifficultytoreachthedistrictitself.Localdrugdeliverymethodsarecurrentlydevelopedtoefficientlypathologiesofinnerear,eyes,SNC,andtotargetdrugstotumors.Awiderangeofdeliverysystemsordevicesforlocaldrugdeliveryhavebeendevelopedandarecurrentlyunderclinicevaluation.TheschoolwillcoverthemaintopicsrelatedtoLocalDrugDelivery,includingissuesfordesigningdeliverysystems,characterizationtools,invitro/invivoapplicationandregulatoryaspects.TheprogramwillincludelessonsfromspeakerswithdifferentexpertiseaswellasoralpresentationbyPhDstudents,inordertoprovideacomprehensiveviewonthetopic.

SchoolDirectors:Prof.BiceConti,UniversitàdegliStudidiPavia,DipartimentodiScienzedelFarmaco,[email protected]. Paola Minghetti, Università degli Studi di Milano, Dipartimento di Scienze Farmaceutiche,[email protected]:Prof.ssaA.M.Fadda UniversitàdegliStudidiCagliariProf.P.Caliceti UniversitàdegliStudidiPadovaProf.M.Carafa UniversitàdiRomaLaSapienzaProf.G.DeRosa UniversitàdegliStudidiNapoliFedericoIIProf.M.Fresta UniversitàMagnaGreciadiCatanzaroProf.P.Minghetti UniversitàdegliStudidiMilanoProf.G.Puglisi UniversitàdegliStudidiCataniaOrganizingCommitteeBiceConti,IdaGenta,RossellaDorati-UniversitàdegliStudidiPaviaPaolaMinghetti,FrancescoCilurzo,FrancescaSelmin,LuciaZema-UniversitàdegliStudidiMilanoSegretariatFondazioneVolta

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Program

Day1 Tuesday,25September2018

12:00–14:00 Registration

14:00 Presentationoftheschoolandwelcome

14:20 MemorialofProfessorNevioPicci

Afternoonsession Localdrugdeliveryinorthopedic,andtissueregenerationstrategies

14:30 Boneregeneration:strategieswhentheframefailsFrancoBenazzo,IRCCSPoliclinicoS.Matteo,Pavia

15:00DevelopmentofadvanceddrugdeliverysystemsusingnaturalbasedmaterialsVitorM.Correlo,UniversidadedoMinho,Braga,Portogallo

15:30 ViscoelasticgelsforintraarticularadministrationLauraMayol,UniversitàdegliStudidiNapoliFedericoII

16:00–17:30 DiscussionGroup1Oralpresentation(max4PhDStudents,15min/presentation)

Aperitifandpostersession

Day2 Wednesday,26September2018

Morningsession1 Drugdeliverytoskinandcutaneousannexes

9:00 UV–DamageandBenefitsStevenNisticò,UniversitàdegliStudidiCatanzaro

9:30 TitletobedefinedCarmeloPuglia,UniversitàdegliStudidiCatania

10:00 Drugdeliverytothenail:ChallengesandrecentdevelopmentsBegoñaDelgado-Charro,UniversityofBath,UK

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10:30–11:30 DiscussionGroup2Oralpresentation(max4PhDStudents,15min/presentation)

Coffeebreak

Morningsession2 Intratumordrugdelivery

12:00Treatingpancreaticcancerwithhyperthermia:TranslationalrequirementsAdrielePrina-Mello,UniversityTrinityCollege,Dublin,Ireland

12:30 Implantableanti-cancerdrugdeliverysystemsDavidStepensky,Ben-GurionUniversityofNegev,Beersheba,Israele

Morningsession3 Cardiacdrugdelivery

13:00Cardiacregenerationafteramyocarcialinfractionusingmicroparticlesand/orcells(ratsandpigs)MariaBlanco-Prieto,UniversityofNavarra

Lunchandpostersession

15:00–16:30 DiscussionGroup3Oralpresentation(max4PhDStudents,15min/presentation)

Coffeebreak

Afternoonsession1 Nasalandpulmonarylocaldrugdelivery

17:00 TitletobedefinedLuigiAllegra,UniversitàdegliStudidiMilano

17:30 LungdeliveryforfightinginfectiousdiseasesRuggeroBettini,UniversitàdegliStudidiParma

Discussioninfrontofthelake

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Day3 Thursday,27September2018

Morningsession Drugdeliverytoeyes

9:00-10:00AutologouslimbalstemcelltransplantationinpatientswithlimbalstemecelldeficiencyGiovanniMilazzo,ChiesiFarmaceuticiParma

10:00–11:30 DiscussionGroup4Oralpresentation(max4PhDStudents,15min/presentations

Coffeebreak

12:00–13:30 DiscussionGroup5Oralpresentation(max4PhDStudents,15min/presentation)

Lunch

Afternoonsession Thefutureinthedevelopmentofmedicines

14.45–15.30 Speakertobedefined

15:30–16.15Developmentofadeliverysystemsforalocaladministration–AcasestudyTorkelGren,Recipharm,Solna,Sweden

16:15–16:45 FormulationandStabilityofhighlypotentanticancerdrugsIreneOddone/GiulianaVerdone,BSPPharmaceuticalsS.p.A.

Coffeebreak

17:00–18:30 DiscussionGroup6Oralpresentation(max4PhDStudents,15min/presentations

Socialevent