HpMTANInhibitor Ki Ki*9fpm 0.81 ± 0.01 nM 0.24 ± 0.02 nMPT03-159 0.54 ± 0.17 nM 0.22 ± 0.04 nM

PT02-159 (?) 2.42 ± 0.51 nM 2.33 ± 0.13 nM

PT-02-186 N/A

PCLMT-O-A (?) 0.11 ± 0.03 nM 0.08 ± 0.02 nM

OVZN709 N/A

KC9-156 N/A

KC9-15 (?) N/A

KC8169A N/AJM132A 0.27 ± 0.04 nM .04 ± 0.01 nM

JM129 0.32 ± 0.01 nM N/AJM1-579 N/ADHL-159 0.21 ± 0.05 nM 0.01 ± 0.03 nMDHL140 N/AAIL091486 0.58 ± 0.19 nM 0.41 ± 0.06 nMKC9-15-C N/ABn-D-A 0.29 ± 0.04 nM 0.31 ± 0.08 nMmMe-Phe-A 1.50 ± 0.26 nM 2.11 ± 0.11 nMpMe-phe-A 1.89 ± 0.21 nM 2.63 ± 0.26 nM

SaMTANInhibitor Ki Ki*mMe-Phe-A 0.63 ± 0.10 nM 1.73 ± 0.22 nMpMe-phe-A 0.41 ± 0.09 nM 1.17 ± 0.15 nM