IMAGING TECHNOLOGIES IN BIOMEDICAL...

13
PROCEEDINGS OF THE 4 th INTERNATIONAL CONFERENCE ON IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information - Bridging the Gap Milos Conference Centre G. Eliopoulos Milos Island, Greece 22-28 September 2007 Editors Roland Itti University Claude Bernard, Lyon, France Efstathios Stiliaris University of Athens and IASA, Athens, Greece

Transcript of IMAGING TECHNOLOGIES IN BIOMEDICAL...

Page 1: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information

PPRROOCCEEEEDDIINNGGSS OOFF TTHHEE 44tthh IINNTTEERRNNAATTIIOONNAALL CCOONNFFEERREENNCCEE OONN

IIMMAAGGIINNGG TTEECCHHNNOOLLOOGGIIEESS IINN BBIIOOMMEEDDIICCAALL

SSCCIIEENNCCEESS

FFrroomm MMeeddiiccaall IImmaaggeess ttoo CClliinniiccaall IInnffoorrmmaattiioonn -- BBrriiddggiinngg tthhee GGaapp

MMiillooss CCoonnffeerreennccee CCeennttrree GG.. EElliiooppoouullooss

MMiillooss IIssllaanndd,, GGrreeeeccee 2222--2288 SSeepptteemmbbeerr 22000077

Editors RRoollaanndd IIttttii University Claude Bernard, Lyon, France EEffssttaatthhiiooss SSttiilliiaarriiss UUnniivveerrssiittyy ooff AAtthheennss aanndd IIAASSAA,, AAtthheennss,, GGrreeeeccee

Page 2: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information
Page 3: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information

FFoorreewwoorrdd

The fourth edition of the ITBS series focused on the theme: “From Medical Images to Clinical Information - Bridging the Gap” was, like the previous ones, the occasion to share both the scientific and technical aspects of medical imaging as well as the clinical implications of recent progress in this field. This kind of meeting is a unique opportunity to bring physicists and engineers together with imaging physicians, in the warm atmosphere of a Greek island. A multidisciplinary approach is the key of the success of this initiative of a group of Greek specialists from both sides, which started in 2001. Designed as a workshop with only a limited number of participants, around one hundred, ITBS 2007 demonstrated nevertheless a substantial program of 75 scientific presentations – 41 oral and 34 posters – coming from 12 countries, not only from Europe, but also from Taiwan (15 papers), Iran (6), the USA (3), China and Ukraine. In addition 9 invited conferences and 4 presentations from industry contributed to the high level scientific event. In contrast with morphological or anatomical imaging, molecular imaging reflects life, normal or abnormal, and its impact on medical diagnosis or follow-up of diseases is of major importance. Despite the rich biological content of the pictures, a crucial question has to be faced: the displayed information is it a true – and even an accurate quantitative – image of reality? Several problems such as radiation attenuation artefacts or lack of proportionality between molecular activity and imaging signal have to be considered. Progress in imaging starts with optimization of the equipment which captures the signal coming from the patient. The improvement of an imaging device is therefore a matter of use of the most adequate radiation and the best way to detect the latent image transported by the radiation. Research work turns around crystals, or combination of crystals, with promising characteristics in terms of sensitivity and spatial resolution, use of non-ionizing radiations, original designs for picture acquisition geometry. In many cases the size of the human body is a limiting factor with regard of the field of view. Technical solutions which cannot be used for large organs can find valuable applications when a smaller field of view is acceptable or even better than a large one. Significant examples where a limited detector size with higher resolution is an advantage are in mammography or small animal imaging. Besides dedicated new or improved instrumentation for humans, small animals represent an alternative population for research and also a technical challenge in terms of spatial resolution of imaging modalities. Improving the contrast of an image between various structures is also an important goal which justifies the development of new contrast media or radiopharmaceuticals. The objective of functional or molecular imaging is the description of the biological behaviour of organs or tissues, looking at metabolism, receptors or cellular activity. Each new molecule opens the field of functional knowledge and diagnosis. There is probably a quite unlimited future for radiochemistry and radiopharmacy. Tremendous efforts made to improve image quality, or to combine imaging modalities for more precise investigations, raise the question of clinical validation of new techniques with correlatively the crucial question of the choice of the comparator, i.e. the reference technique. This is also valid, and even more critical, when a computer is supposed to help the physician by adding artificial intelligence to the human thinking.

Page 4: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information

ITBS in Milos Island is the place where all pertinent questions turning around medical imaging can be discussed. All kind of radiation detectors, 3D imaging designs, imaging agents or modalities, image processing methods, computerized diagnosis and clinical applications are within the scope of ITBS and the next 2009 issue will certainly afford a new amount of innovation.

Roland Itti Nuclear Medicine

Lyon, France

Page 5: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information

LLiisstt ooff PPaarrttiicciippaannttss

TITLE SURNAME FIRST NAME

AFFILIATION

Ms. Andreou Maria Physics Department, University of Athens, GR

Dr. Archimandritis Spyridon N.C.S.R. "Demokritos", GR

Mr. Arikidis Nikolaos Department of Medical Physics, University of Patras, GR

Mr. Bardies Manuel INSERM U601, Nantes, FR

Dr. Beer Simone Central Institute for Electronics, Forschungszentrum Juelich, DE

Dr. Boniatis Ioannis Department of Medical Physics, University of Patras, GR

Dr. Bonissent Alain CPPM, Marseille, FR Ms. Camarda Manuela Dip. di Fisica, University di Pisa, IT Dr. Carney Jonathan University of Pittsburgh, USA Dr. Cassol Brunner Franca CPPM/IN2P3 (CNRS), Marseille, FR Dr. Costaridou Lena University of Patras, GR

Mr. Daskalakis Antonios Department of Medical Physics, University of Patras, GR

Dr. Delis Harry University of Patras, GR Mr. Gayshan Vadim ScintiTech, Inc., Waltham, USA

Mr. Georgiev Verislav Department of Medical Physics, University of Patras, GR

Prof. Giokaris Nikos University of Athens & IASA, GR Prof. Goris Michael Stanford University School of Medicine, USA Ms. Gourni Eleni N.C.S.R. "Demokritos", GR Mr. Gouskos Loukas Physics Department, University of Athens, GR Prof. Hofmann Michael Molecular Imaging and Therapy, Bern, CH Dr. Houzard Claire Hopital Lyon Sud, FR Prof. Hsiao Ing-Tsung Chang Gung University, TW

Prof. Itti Roland Nuclear Medicine, Groupement Hospitalier Est, Lyon, FR

Dr. Kalyvas Nektarios Technological Institution of Athens, GR Dr. Kam Boen Liong Erasmus MC, Rotterdam, NL Mr. Kantemiris Ioannis Physics Department, University of Athens, GR Prof. Karabarbounis Andreas University of Athens & IASA, GR Dr. Karaiskos Pantelis Medical School, University of Athens, GR Dr. Karanasiou Irene National Technical University of Athens, GR

Prof. Kerek Andras Royal Institute Of Technology, Physics Dept, Stockholm, SE

Dr. Knoop Bernd Hannover Medical School, Clinic For Nuclear Medicine, DE

Ms. Kokkinou Evdoxia Department of Medical Physics, University of Patras, GR

Mr. Korfiatis Panagiotis Department of Medical Physics, University of Patras, GR

Mr. Koutalonis Matthaios Department of Medical Physics, University of Patras, GR

Mr. Lagares Juan Ignacio

CIEMAT, Madrid, ES

Page 6: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information

Dr. Lanconelli Nico INFN Bologna, IT

Dr. Le Pape Alain Small Animal Imaging Center-CDTA-CNRS, Orleans, FR

Mr. Liang Chia-Hao National Yang Ming University, Taipei, TW Ms. Magkrioti Christiana N.C.S.R. "Demokritos", GR Prof. Maintas Dimitris Institute of Isotopic Studies, Athens, GR Ms. Mathikoloni Dorita University of Athens, Physics Department, GR

Ms. Michopoulou Sofia Department of Medical Physics, University of Patras, GR

Mr. Moutsatsos Argyrios University of Athens, Medical School, GR Mr. Ozdemir Mahir Sinan Gent University, BE Dr. Papagiannis Panagiotis University of Athens, Medical School, GR Mr. Petrokokkinos Loukas University of Athens, Physics Department, GR Ms. Polychronopoulou Athanasia University of Athens, Physics Department, GR Mr. Rault Erwann Gent University, BE

Mr. Sakellaris Taxiarchis Department of Medical Physics, University of Patras, GR

Ms. Salpea Paraskevi NCSR Demokritos, Department of Biology, GR Mr. Seremetis Dimitrios ENGEFALOS, GR Prof. Stiliaris Efstathios University of Athens & IASA, GR Ms. Stiliari Joanna University of Athens, Physics Department, GR Dr. Tekabe Yared Columbia University, USA Mr. Thanasas Dimitris University of Athens, Physics Department, GR Prof. Todd-Pokropek Andrew University College London, UK Mr. Valais Ioannis Technological Educational Institute, GR Mr. Van Holen Roel Gent University, BE Mr. Verhaeghe Jeroen Gent University, BE Dr. Weitzel Thilo Insel Spital Bern, Dept. Nuclear Medicine, CH Ms. Yeh Mai-Yu Chang Gung University, Tao-Yuan, TW

Mr. Zhou Rong Institute of Medical Physics and Engineering, Beijing, PRC

Ms. Zioga Maria University of Athens, Physics Department, GR

Page 7: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information

CCoonnffeerreennccee PPhhoottooss

Page 8: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information
Page 9: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information
Page 10: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information
Page 11: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information
Page 12: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information
Page 13: IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCESej.iop.org/pdf-nfs/jinst/ITBS07_Proceedings_reduced.pdf · IMAGING TECHNOLOGIES IN BIOMEDICAL SCIENCES From Medical Images to Clinical Information

TThhee IITTBBSS 22000077 CCoonnffeerreennccee wwaass oorrggaanniizzeedd bbyy

TThhee IInnssttiittuuttee ooff AAcccceelleerraattiinngg SSyysstteemmss && AApppplliiccaattiioonnss ((IIAASSAA))

aanndd

TThhee NNaattiioonnaall && KKaappooddiissttrriiaann UUnniivveerrssiittyy ooff AAtthheennss

aanndd ssuuppppoorrtteedd bbyy

TThhee SS&&BB IInndduussttrriiaall MMiinneerraallss SS..AA..

TThhee GGrreeeekk MMiinniissttrryy ooff EEdduuccaattiioonn