• Probiotics and Nutraceuticals• Microbial genetics• Antimicrobial chemotherapy• Molecular virology, Recombinant DNA technology• Structural Biology and Protein Chemistry• DNA-interacting Molecules• Enzyme Inhibitors• Structure Function of Proteins• Nucleosides as Antivirals• Biomimetic Chemistry of Metals• Computer Simulations of Biomolecules

• Bio Hydrogen Lab• Bio Process Lab • Biochemical & DSP  Lab• Cell & Molecular Biology Lab • Micro & Immunotech Lab • Plant Biotech Lab• Computation Lab• Medical Biotechnology Lab• Fermentation Technology Lab

• Air-lift bioreactor• Atomic absorption

spectrophotometer• Centrifugal evaporator• Darkroom/Cold room /

Radio-isotope facilities• DNA finger printing• ELISA reader• Fermentation Technology• Gas Chromatograph• High speed refrigerated

cooling centrifuge• Liquid nitrogen storage

facility• Milli-Q water purifier

• Netzs Thermal Analyzer (DSC, TGA, DTA)

• Perkin Elmer FT IR Spectrometers

• Perkin Elmer CHN Analyzer

• Digital Polarimeter (JASCO)

• Fluorimeter • CH Electrochemical

Analyzer • Thermal Analyser • UV & Visible

Spectrophotometer• Bruker AC 200 MHz NMR

Spectrometer • Cyclic Voltammeter

Model P9001

1) Magnetic Nano-Particle for Cancer Diagnostics2) Extraction of Chemical from Marine Bacteria

for Chemotherapy3) Anti-Diabetic Drug from a Probiotic Bacterium4) Bench-Scale Technology for Manufacture of

Pro-Biotics5) Non Invasive Sterile Drug and Device

Manufacturing System6) Extraction of Polyphenols from Green Tea

Leaves7) Smart-Reversible Inhibition of Sperm Under

Guidance

• Technology development & transfer for selected medicinal plants: approach through R&D and ex-situ cultivation

• Biosynthetic silk hydrogel extracellular matrix analogues for mammalian cell support and drug delivery

• Studies on the immunomodulatory properties of Aloe vera gel and its products

• Exploring the immunomodulatory potential of mushroom glucan/proteoglucan as Biological response modifier in cancer therapy

• Enantiomeric separation of chiral drugs by micellar electrokinetic capillary chromatography

• A rational approach towards anticancer drugs and chemosensors

• Herbal/ bioproduct development

• Water pipe fermented tobacco products

• Biocatalyst based continuous production of biodiesel

• The UC Berkeley – IIT Kharagpur collaboration focused on biofuels (energy), and biotech (healthcare)

• Indo-Norwegian- Institute collaboration on Characterization of two histidine kinases and their cognate response regulator

Research Hub Strong intellectual capital Produces unparalleled technically

competent students Healthy balance of core and non core

engineering courses Emphasis on hands on, learn as you do

approach Numerous successfully completed projects

USP

• Low cost• high efficiency for detection • better than the conventional

X-ray technique • Perfectly harmless to the body

FEATURES

•Magnetic nano-particle coated with folic acid

•After injection to patient the particle is absorbed selectively by cancer cell and the lesion is easily identified by Magnetic Resonance Imaging

FEATURES

• Biosurfactants isolated from a marine bacterium are found to have significant antimicrobial activity and can be used in chemotherapy.

USP

•Non-hemolytic in nature

•Does not harm normal cell lines due to low concentration

•Shows properties such as metal binding, emulsification

USP

• First anti-hyperglycemic exo-polysaccharide molecule from a pro-biotic

• GRAS(Generally Regarded As Safe) by US FDA

• Potential drug candidate for both type 1 and type 2 diabetes.

• far better results in comparison with standard drugs for type 2 diabetes

• Biodegradable, non- toxic and has no side effects

FEATURES

•An exo- polysaccharide with potential anti-diabetic activity•Produced by simple fermentation and purification process•Characterized in terms of sugar monomers and its ability to reduce blood glucose levels in an animal model.

USP

• Confirms to all the characteristics of a GRAS organism (US FDA)

• Produced endospores can be stored under non-refrigirative condition

• Very high potency and L(+) Lactic acid levels

• Proven to produce bacteriocin like antimicrobial substances, antioxidant exopolysaccharides

FEATURES

•Manufacturing endospores of a pro-biotic bacterium at a lab scale•Can lead to development of some neutrateuticals•Maximum of 6 x 1012 spores/gm have been obtained•The process is optimized and stabilized in a 10 l reactor

USP

• Cost effective (70% less than conventional clean room facility)

• Minimal manufacturing zone is maintained at the best ‘Clean’ conditions

• No requirement of electricity or human operator

• Less particle contamination and transparency maintained by glass or polymeric sheet

FEATURES•Sterile drug or a device manufacturing system with controlled and enclosed micro-environment•All manipulations are performed by magnetic coupling across the enclosure and mini-robots placed within, controlled by electromagnetic coupling•No invasion of operating personnel; gloves; control cords into the manufacturing space

USP• “Green Process“-

absolutely safe for human consumption

FEATURES

•Centrifugation of tea juice, followed by special membrane based filtration process and drying of concentrated liquor to produce 60-70% pure polyphenol powder•Based on water extraction - without addition of any chemicals

USP

• Composition is made to be effective for more than 10 years (long lasting)

• Safe with almost no side effects

• Antimicrobial• Non-surgical• Cost effective

FEATURES

•Non-hormonal male injectable contraceptive in the form of a clear gel

•Within an hour after injecting into the vas deferens, produces an electrical charge to nullify electrical charge of spermatozoa