III.trisomy21III.trisomy21III.trisomy21III.trisomy21III.trisomy21
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10/20/11 1 Trisomy 21 • Non-disjunction • Robertsonian Translocation • Mosaicism in meiosis I
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III.trisomy21III.trisomy21III.trisomy21III.trisomy21
Transcript of III.trisomy21III.trisomy21III.trisomy21III.trisomy21III.trisomy21
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10/20/11
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Trisomy 21
Non-disjunction Robertsonian Translocation Mosaicism
in meiosis I
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in meiosis II in meiosis I
24 24 22 22 24 22 23 23
A B C
= chr 21
21
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chr 21
The resulting embryo would be expected to show Trisomy 21 1-2% of clinically recognized Down Syndrome
