Ian Graham et al. European Heart Journal 2007;28:2375-414
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Transcript of Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
Classes of recommendations
Ian Graham et al. European Heart Journal 2007;28:2375-414
Levels of evidence
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
All deaths from circulatory disease in EuropeAll ages - Year 2000 or circa
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
The relationship of total cholesterol (TC):HDL cholesterol ratio to 10-year fatal CVD events in men and women aged 60 years with and without risk
factors, based on a risk function derived from the SCORE project
Ian Graham et al. European Heart Journal 2007;28:2375-414
Impact of combinations of risk factors on risk
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
Advantages in using the SCORE risk chart
• Intuitive, easy to use tool• Takes account of the multifactorial nature of CVD• Estimates risk of all atherosclerotic CVD, not just CHD• Allows flexibility in management - if an ideal risk factor level
cannot be achieved, total risk can still be reduced by reducing other risk factors
• Allows a more objective assessment of risk over time • Establishes a common language of risk for clinicians• Shows how risk increases with age• The new relative risk chart helps to illustrate how a young person
with a low absolute risk may be at a substantially higher and reducible relative risk.
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
Ian Graham et al. European Heart Journal 2007;28:2375-414
SCORE chart: 10-year risk of fatal CVD in populations at high CVD risk based on the following risk factors: age, gender,
smoking, systolic blood pressure, and total cholesterol
Ian Graham et al. European Heart Journal 2007;28:2375-414
SCORE chart: 10-year risk of fatal CVD in populations at low CVD risk based on the following risk factors: age, gender,
smoking, systolic blood pressure, and total cholesterol
Ian Graham et al. European Heart Journal 2007;28:2375-414
SCORE chart: 10-year risk of fatal CVD in populations at high CVD risk based on the following risk factors: age, gender, smoking,
systolic blood pressure, and total cholesterol: HDL cholesterol ratio
Ian Graham et al. European Heart Journal 2007;28:2375-414
SCORE chart: 10-year risk of fatal CVD in populations at low CVD risk based on the following risk factors: age, gender, smoking,
systolic blood pressure, and total cholesterol: HDL cholesterol ratio
Ian Graham et al. European Heart Journal 2007;28:2375-414
Relative risk chart
Ian Graham et al. European Heart Journal 2007;28:2375-414