Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells...

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Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD

Transcript of Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells...

Page 1: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Howard County 4th Annual Health & Wellness ExpoMay 1, 2015

Boost Your Brain:Regenerate Cells Critical to

Memory & Learning

Majid Fotuhi, MD PhD

Page 2: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

New Discoveries

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Page 3: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

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“This book may be the most important you’ll ever read. Certainly, what Dr. Fotuhi teaches in this book has

changed my life.”

Michael Roizen, M.D. Chairman of the Wellness Institute- The Cleveland Clinic

Page 4: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

“Dr. Fotuhi has summarized the latest discoveries that show how we can grow our

brains bigger and stronger…”

Mehmet Oz, M.D.

The Dr. Oz Show

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Page 5: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Objectives What happens to our brain

with aging? How to reverse age-related

brain atrophy? Brain Fitness Program

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Page 6: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Short-term: HippocampusLong-term: Cortex

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Cortex Hippocampus

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Hippocampus

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Beautiful Neurons in Hippocampus

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With Aging, Hippocampus Atrophies Faster

than the Rest of the Brain

Hippocampus shrinks by about 0.5% per year after age 50

That is the reason memory lapses become more frequent after age 50

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What CausesAtrophy in Hippocampus?

Obesity Stroke

Sleep Apnea

ConcussionAlzheimer’s

Diabetes

Hypertension

Stress

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Less Brain Volume in Patients with Sleep Apnea

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Am J Respir Crit Care Med 2002; 166:1382–7

Page 12: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Obesity Shrinks the Brain

Associated with reduced brain volume

Ward, et al., 2005

Slows cognitive function

Debette, et al., 2011

Brains of overweight and obese individuals appeared 8 and 16 years older, respectively

Raji, et al., 2010

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Brain Research Volume 1280, 14 July 2009, Pages 186–194

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Multiple Risk Factors Shrink the Hippocampus

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MultipleRisk Factors

No Risk Factors

HippocampusHippocampus

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Smaller Hippocampus in football players, With or Without Documented

Concussion

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Singh et al, JAMA 2014

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Stress Shrinks Brain Cells in Hippocampus

StressControl

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Depression Shrinks the Brain

The number of days of depression is associated with the severity of hippocampal atrophy

Sheline, et al, (1996). PNAS, 93(9);3908-13.

Depression is associated with impaired memory, executive function and processing speed

Egger et al, (2008). Psychiatry Research: Neuroimaging; 164(3): 237-44)

Sheline, (1996). PNAS, 93(9);3908-13.

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Page 17: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Why do we forget names?

Hypertension Diabetes Alcoholism Depression Heart failure Obesity High cholesterol Head trauma Aging

Poor sleep Too much work Information overload Too many

responsibilities Fatigue Poor attention Poor diet “Can’t do it”

mentality

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Page 18: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

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DiabetesHypertensionObesitySleep ApneaHead TraumaGenesStress

Physical FitnessCognitive StimulationBrain-healthy DietMeditation

Page 19: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Objectives What happens to our brain

with aging? How to reverse age-related

brain atrophy? Brain Fitness Program

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6 Steps to Grow Your Brain

1. Get Fit

2. Tease Your Memory

3. Mediterranean Diet – DHA-EPA

4. Sleep Well

5. Focus Your Mind

6. Start Today

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1. Get Fit: Hippocampus Grows Bigger with Exercise

Erikson, PNAS 2011

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Page 22: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Arch Gen Psychiatry, 2010

Hippocampus Grows Biggerwith Exercise, Even After 3

Months

After

Before

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More Exercise: More Brain Cells

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Draganski et al. J Neurosci 2006; 26:6314–7

2. Tease Your Memory: Hippocampus Grows Bigger with

Memorization Training

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3. “Mediterranean Diet” plus DHA-EPA

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More DHA-EPA: Bigger Hippocampus

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Pottala J V et al. Neurology 2014;82:435-442

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4. Sleep Well: Hippocampus Grows Bigger with Treatment of Sleep Apnea

Canesa, American Journal of Respiratory Medicine, 2011

Page 28: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

5. Focus Your Mind: Hippocampus Grows Bigger with

Meditation

28Holzel , Psychiatric Research, 2011

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Neurofeedback

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Performed by a certified EEG neurofeedback specialist

Live EEG feedback is provided through auditory and visual responses to help the patient move brain activity towards an optimal state

Benefits are long-lasting

Page 30: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Neurofeedback Improves Brain Function and Increases Volume of

Cortex

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Ghaziri et al. Clin EEG Neurosci 2013; 44 (4) 265-72

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6. Start Today: Hippocampus Grows Bigger When You Start

Early

Page 32: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Objectives What happens to our brain

with aging? How to reverse age-related

brain atrophy? Brain Fitness Program

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Page 33: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Brain Fitness Program

Initial appointmen

twith

neurologist

Diagnostics Follow-Up

Brain Fitness

Program: Level 1

Level 2

Level 3

Other StandardTreatment

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Page 34: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

BFP: Evaluating &Treating All Causes of anxiety and depression

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BFP

MedicineN

euro

logy

Psychology

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DiabetesHypertensionObesitySleep ApneaHead TraumaGenesStress

Brain-healthy DietPhysical FitnessCognitive StimulationMeditation

Page 36: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

Brain Fitness Program: Goals

Short Term Think faster Remember more Improve efficiency

of problem solving Sharpen focus React quicker Enhance self

esteem Brighten mood

Long Term Help to regrow brain

cells in hippocampus Establish a brain

healthy lifestyle change that results in lifelong benefits

Reduce risk of dementia in late-life

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Page 37: Howard County 4 th Annual Health & Wellness Expo May 1, 2015 Boost Your Brain: Regenerate Cells Critical to Memory & Learning Majid Fotuhi, MD PhD.

THANK YOU!

[email protected]

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