THE SPHERONIZATION COMPANY

Celebrating 50 Years as market leader in manufacturing and developing

equipment for the production of pellets or extrudate (beads or spheroids) by Extrusion

and Spheronization™ from Caleva®.

ABOUT USA market leader in manufacturing and developing equipment

for the production of pellets (beads or spheroids) by Extrusion

and Spheronization™

HISTORY

For over 50 years Caleva Process Solutions have designed and

manufactured high quality products that have shaped the way

our clients understand extrusion and spheronization.

We work in close partnership with our customers from various

backgrounds in their developments that surround the need to

make pellets and extrudates using the processes of extrusion

and spheronization.

If you are involved in the pharmaceutical, catalyst or ceramic

industries (beads) and are thinking about extrusion and

spheronization to make pellets then talk to Caleva.

DISTRIBUTORSWHERE WE OPERATE

EUROPE

THE AMERICAS

ASIA

MIDDLE EAST AND AFRICA

CALEVA MULTI LAB

A single bench top unit offering you advantages for university

teaching that is cost effective to purchase, easy and safe to

use and is robust in the hands of student users.

Offers best use of your benchtop space. You will have a safer

and more efficient work environment. “Tool-Less Technology”

reduces cleaning time and increases interaction of your students.

Suitable for a wide range of material, from easily mixed pharmaceutical

formulations to less easy to mix catalyst and inorganic mixes for the

petrochemical industry.

Use batches from 10g up to 100g whilst

saving your bench space and offering you a

high level of flexibility for your student groups

TABLET AND PELLET

MINI COATER DRIERYou can achieve excellent uniformity within and between

batches whilst reducing your product cost and overcome

limited product availability.

Ease of use together with the possibility to coat very small

batches makes the MCD-2 particularly attractive both for

university teaching and research laboratories.

From a single tablet up to about 150 tablets

From a few grams to about 60 grams of small pellets

From a single capsule to a "small handful"

MIXER TORQUE

RHEOMETERThe Caleva Mixer Torque Rheometer is well established as a

valuable formulation development, formulation research and

production quality control tool.

It will uniquely provide you with quantitative and reproducible

measurement of the rheology of a wet mass.

Having this information will enable you to optimize your

formulations in the least possible time. It will enable you

to investigate product and excipient quality issues in a

quantitative and meaningful way.

The data can be used as part of scale-up and the instrument

can also be used for quality control in production. The MTR-3

is designed to enable the user to quantify the consistency

properties of a wet mass.

MULTI BOWL

SPHERONIZER

EXTRUDER AND SPHERONIZER WITH

BATCH SIZE FLEXIBILITY

FROM 50 GRAMS TO 1.5 KG

If you plan to work with batch sizes from between 50 g and

1500 g then this Caleva kit will give you the flexibility you need.

The Multi-Bowl Spheronization Kit is designed for your

laboratory bench-top and includes the following 2 pieces

The Caleva bench-top screen Extruder 20 and Caleva

Multi Bowl Spheronizer base with a 250mm, 120 mm,

85mm or 60mm diameter bowl.

VARIABLE DENSITY KITEXTRUDER AND SPHERONIZER WITH BATCH SIZE

FLEXIBILITY FROM 50 GRAMS TO 1.5 KG

The Caleva variable Density Kit will allow you to develop pellets

with different densities, thus widening your chance of

achieving a successful formulation. The kit is made up of the

Caleva Variable Density Extruder and the Multi Bowl Benchtop

Spheronizer with a 250 mm diameter bowl attached.

The Caleva Bench-top Variable Density Extruder and Caleva

Multi Bowl Spheronizer base with a 250mm, 120 mm,

85mm or 60mm diameter bowl.

HIGH DENSITY KIT

EXTRUDER AND SPHERONIZER WITH

BATCH SIZE FLEXIBILITY

FROM 2 TO 8 KGs

The Caleva Gear Extruder high density Extrusion and Spheronization

kit is a small scale production kit with an output between about 40

to 60 kg per hour linked with a Caleva Spheronizer 500.

The Caleva gear extruder 40 and Caleva

Spheronizer 500 base with 500mm diameter bowl.

50KG PER HOUR

SPHERONIZER KIT

EXTRUDER AND SPHERONIZER WITH

BATCH SIZE FLEXIBILITY

FROM 250 GRAMS TO 4 KG

The 50 kg/h system for your product development, and for

your contract manufacture. You can clean it quickly and

change your products regularly. This rapid cleaning allows

you to work with different products in the same equipment

leading a more efficient use of your time and resources.

The Caleva screen Extruder 35 and Caleva

Spheronizer 380 base with a 380mm diameter bowl.

100KG PER HOUR

SPHERONIZER KIT

EXTRUDER AND SPHERONIZER

WITH BATCH SIZE FLEXIBILITY

FROM 1 TO 8 KG

With the Caleva 100 kg/hour System you can easily dismantle

and clean this equipment to allow you to work with different

products using this “easy to clean” system. Do you want to

spend more time producing and less time cleaning!

The Caleva screen Extruder 35 and Caleva

Spheronizer 500 base with a 500mm diameter bowl.

150KG PER HOUR

SPHERONIZER KIT

EXTRUDER AND SPHERONIZER

WITH BATCH SIZE FLEXIBILITY

FROM 2 TO 15 KG

Product trials show that this very compact yet efficient

extruder can produce in excess of 250 kg of extrudate

per hour using axial extrusion.

Other die patterns and shapes suitable for “industrial”

materials in the catalyst and petrochemical industries

are available and are proving to be extremely successful..

The Caleva twin screw Extruder TSE70 and Caleva

Spheronizer 700 base with a 700mm diameter bowl.

VARIABLE DENSITY TWIN

SCREW EXTRUDER

PRODUCTION EXTRUDER WITH

THROUGHPUT CAPACITY

OF UP TO 250 KG PER HOUR

Product trials show that this very compact yet efficient

extruder can produce in excess of 250 kg of extrudate

per hour using axial extrusion.

Other die patterns and shapes suitable for “industrial”

materials in the catalyst and petrochemical industries

are available and are proving to be extremely successful..

APPLICATION NOTES & INTERESTING BLOG

ARTICLESSAVE TIME AND COST IN YOUR PRODUCT DEVELOPMENT with the Mixer Torque Rheometer

A PRACTICAL EXAMPLE OF OF “END POINT” DETERMINATION USING THE CALEVA MIXER TORQUE RHEOMETER RESULTS OF A MIXING TRIAL USING THE CALEVA MULTI LAB MIXER/GRANULATOR WITH SOME DIFFICULT MATERIALS

Caleva Mixer Torque Rheometer - The importance of mixing time for your formulation development and production

What type of extruder do I need?

It is possible to purchase extruders and spheronizers at a lower price .... but will it cost you more in the longer term?

Mini Coater Drier results - can they be used in the scale up of process development?

Coating of very small capsules with the Caleva Mini Coater Drier

What characteristics should my extrudate have?

Are you working with thick, viscous or sticky granulations?

How do I mix very small batches of my product?

Can you help with my cosmetics formulation?

Catalyst Pellets cracked! The strange apple sauce method