7/26/2019 Hormonal Secretion of Pancreas

1/17

CNQJNDGF ]KMQKY@ND NB _GDMQKG](_GDMQKG] 7)

FKGQD@DL NAHKMY@RK8

Gt tck kdi nb fkmturk stuikdt scnufi ak gafk tn ednw8

\cgt `s pgdmrkgs.

Kdinmr`dk gdi kxnmr`dk pnrt`nd nb pgdmrkgs,

@dsuf`d skmrkt`nd.

@dsuf`d kbbkmts.

I`gakt`m jkff`tus

_GDMQKG]

G tr`gdlufgr lfgdi, G `nds wc`mccgs antc kxnmr`dk gdikdinmr`dk mkffs, fnmgtki akc`di

tck stnjgmc. G iugf nrlgd cgv`dl twn

budmt`nds8n Kxnmr`dk Budmt`nds.n Kdinmr`dk Budmt`ndsn

KSNMQ@DK B[DMY@ND]8

n Yck kxnmr`dk budmt`nd nb tck pgdmrkgs `s fnmgf`zki `d tckgm`dgr mkffs.

n Gm`dgr mkffs `dvnfvks sydtcks`s gdi skmrkt`nd nb i`lkst`vkhu`mkspgdmrkgt`m hu`mk.

7/26/2019 Hormonal Secretion of Pancreas

2/17

n _fgys gd `jpnrtgdt rnfk dtck i`lkst`nd nb prntk`dsgdi f`p`is.

n Cgs j`fi i`lkst`vk gmt`nd

nd mgrancyirgtks.

KDINMQ@DKB[DMY@ND]8

n _krbnrjki ay tck `sfkts nbFgdlkrcgds.

n @dvnfvks prniumt`nd nbcnrjndks.

n Cujgd pgdmrkgs mndtg`d 71 j`ff`nd `sfkts.

@]FKY] NB FGDLKQCGD]

NQLGD ]P]YKJ] _GDMQKG]

G tr`gdlufgr lfgdi.

Yckrk grk twn i`st`dmt w`tc`d tck pgdmrkgs

Yck kxnmr`dk pnrt`nd nb tck pgdmrkgs `s jgik up nb gm`d` gdi

iumtgf systkjs.

GM@DGQ MKFF] MNDYG@D XPJNLKD

7/26/2019 Hormonal Secretion of Pancreas

3/17

NQLGD ]P]YKJ] _GDMQKG]

Yck kdinmr`dk pnrt`nd nb tck pgdmrkgs `s skrvki aystrumturks mgffki tck `sfkt nb Fgdlkrcgds

7/26/2019 Hormonal Secretion of Pancreas

4/17

n Yck `sfkt nb Fgdlkrcgds cgvk skvkrgfi`st`dmt mkff typks

Gfpcg mkffs-prniumklfumglnd gdi mndst`tutk

gpprnx`jgtk 1;% nb tcktntgf `sfkt mkff dujakr.

Aktg mkffs-tck `dsuf`dprnium`dl mkffs (jghnr`ty nbtck mkffs)

Ikftg mkffs-prniumksnjgtnstgt`d

@D][F@D

Cnrjndk nb dutr`kdt gaudigdmk G prntk`d cnrjndk mnds`st`dl nb twn

gj`dn gm`i mcg`ds f`deki ay i`sufb`ikandis

]ydtcks`zki gs pgrt nb prn`dsuf`d (32 GG)gdi tckd kxm`ski ay kdzyjks, rkfkgs`dl budmt`ndgf `dsuf`d(;7 GG) gdi M pkpt`ik (10 GG).

@dsuf`d `s skmrktki `d rkspndsk tn c`lc afnni sulgr, gftcnulc

g fnw fkvkf nb `dsuf`d `s gfwgys skmrktki ay tck pgdmrkgs. Gbtkr g jkgf, tck gjnudt nb `dsuf`d skmrktki `dtn tck afnni

`dmrkgsks gs tck afnni lfumnsk r`sks.

F`ekw`sk, gs afnni lfumnsk bgffs, `dsuf`d skmrkt`nd ay tckpgdmrkgt`m `sfkt aktg mkffs ikmrkgsks.

@d rkspndsk tn dsuf`d, jusmfk mkffs,, gdi bgt mkffs tgeklfumnsk `d brnj tck afnni, wc`mc uft`jgtkfy fnwkrs tck c`lcafnni lfumnsk fkvkfs agme tn tck dnrjgf rgdlk.

@dsuf`d ]trumturk Fgrlk pnfypkpt`ik ;7 GG (J\ 2???)

Ynw mcg`ds f`deki ay i`sufb`ik andis.

G mcg`d (17 GG)

7/26/2019 Hormonal Secretion of Pancreas

5/17

A mcg`d (=? GG)

= i`sufb`ik andis.

DNQJGF @D][F@D JKYGANF@]J

@dsuf`d `s g pkpt`ik cnrjndk mnjpnski nb ;7 gj`dngm`istcgt `s sydtcks`zki, pgmeglki gdi skmrktki `d tck pgdmrkgt`maktg mkffs.

Yck jghnr rklufgtnr nb `dsuf`d skmrkt`nd `s lfumnsk wc`mc gmtsantc i`rkmtfy gdi ay guljkdt`dl tck gmt`nd nb ntckr `dsuf`dskmrktglnluks.

G r`sk `d tck afnni lfumnsk fkvkfs, mgusks gd jjki`gtkrkfkgsk nb `dsuf`d, prksujgafy tcgt `s stnrki `d tck aktg-mkff

lrgdufks. @b tck skmrktnry st`jufus pkrs`sts, g ikfgykirkspndsk bnffnws, wc`mc `dvnfvks gmt`vk sydtcks`s nb `dsuf`dbrnj tck aktg-mkffs.

Ntckr glkdts, `dmfui`dl `dtkst`dgf cnrjndks gdi mkrtg`dgj`dngm`is (fkum`dk gdi grl`d`dk), gs wkff gs sufbndyfurkgs,st`jufgtk `dsuf`d rkfkgsk.

@D][F@D ]PDYCK]@] @dsuf`d lkdk kdmniks g fgrlk prkmursnr nb `dsuf`d

(prkprn`dsuf`d)

Iur`dl trgdsfgt`nd, tck s`ldgf pkpt`ik `s mfkgvki (prn`dsuf`d)

Iur`dl pgmegl`dl `d lrgdufks ay Lnfl`, prn`dsuf`d `s mfkgvki`dtn `dsuf`d gdi M pkpt`ik

_rntk`d gdi _nfypkpt`ik ]ydtcks`s gdi Qkfkgsk

@dsuf`d sydtcks`s `s st`jufgtki ay lfumnsk nr bkki`dl gdiikmrkgski ay bgst`dl.

Ycrkscnfi nb lfumnsk-st`jufgtki `dsuf`d skmrkt`nd `s 7??jl/if.

Lfumnsk rgp`ify `dmrkgsk tck trgdsfgt`nd nb tck dsuf`d jQDGgdi sfnwfy `dmrkgsks trgdsmr`pt`nd nb tck `dsuf`d lkdk.

7/26/2019 Hormonal Secretion of Pancreas

6/17

_QNYK@D GDI _NFP_K_Y@IK ]PDYCK]@] GDIQKFKG]K

@D][F@D ]PDYCK]@]

FKRKF]

Afnni lfumnsk `s dnrjgffy jg`dtg`dki aktwkkd

7/26/2019 Hormonal Secretion of Pancreas

7/17

Afnni lfumnsk fkvkfs akfnw

7/26/2019 Hormonal Secretion of Pancreas

8/17

n tr`llkrs tck rkfkgsk nb lfymnlkd bnrj f`vkr stnrks gdin ckfps tn rg`sk tck fkvkf nb lfumnsk (sulgr) `d tckn afnnistrkgj.

n Aktg mkffs - rkfkgsk tck cnrjndk `dsuf`d, wc`mc ckfp rklufgtkmgrancyirgtk jktganf`sj `dtn tck afnnistrkgj.

B[DMY@ND] NB @D][F@D

@dsuf`d `s g jghnr gdganf`m cnrjndk. @t s dkmkssgry bnr8n Yrgdsjkjargdk trgdspnrt nb lfumnsk gdi gj`dngm`isn Lfymnlkd bnrjgt`nd `d tck f`vkr gdi sekfktgf jusmfks

n Lfumnsk mndvkrs`nd tn tr`lfymkr`iksn Dumfk`m gm`i sydtcks`sn _rntk`d sydtcks`s

@ts pr`dm`pgf jktganf`m budmt`nd `s tn `dmrkgsk tck rgtk nblfumnsk trgdspnrt `dtn mkrtg`d mkffs `d tck aniy. Ycksk grktck str`gtki jusmfk mkffs, `dmfui`dl jynmgri`gf mkffs,

7/26/2019 Hormonal Secretion of Pancreas

9/17

b`arnafgsts, gdi bgt mkffs, rkprkskdt`dl mnffkmt`vkfy ganut 1/=nb tck kdt`rk aniywk`lct.LF[MN]K @] YCK _Q@JGQP ]Y@J[FGYNQ NB @D][F@D]KMQKY@ND

7/26/2019 Hormonal Secretion of Pancreas

10/17

QKL[FGY@ND NB @D][F@D ]KMQKY@ND

Dn `dsuf`d `s prniumki wckd pfgsjg lfumnsk akfnw ;? jl/if

Cgfb-jgx`jgf `dsuf`d rkspndsk nmmurs gt 7;? jl/if

G jgx`juj `dsuf`d rkspndsk nmmurs gt =?? jl/if

@dsuf`d skmrkt`nd `s a`pcgs`m8n [pnd lfumnsk st`jufgt`ndgd `d`t`gf aurst nb skmrkt`nd (;-7;

j`d.)n Yckd g skmndi pcgsk nb lrgiugf `dmrkjkdt tcgt fgsts gs fndl

gs afnni lfumnsk `s c`lc

@D][F@D ]KMQKY@ND @] A@_CG]@M

7/26/2019 Hormonal Secretion of Pancreas

11/17

@D][F@D ]@LDGF@DL

@D][F@D GMY@ND ND MKFF]8

7/26/2019 Hormonal Secretion of Pancreas

12/17

@D][F@D GMY@ND ND MGQANCPIQGYK JKYGANF@]J8

F`vkr8

]t`jufgtks lfumnsk nx`igt`nd

_rnjntks lfumnsk stnrglk gs lfymnlkd

@dc`a`ts lfymnlkdnfys`s

@dc`a`ts lfumndknlkdks`s

Jusmfk8

]t`jufgtks lfumnsk uptgek (LF[Y9)

_rnjntks lfumnsk stnrglk gs lfymnlkd

@dsuf`d Gmt`nd nd Mgrancyirgtk Jktganf`sj

Gi`pnsk Y`ssuk8

]t`jufgtks lfumnsk trgdspnrt `dtn gi`pnmytks

_rnjntks tck mndvkrs`nd nb lfumnsk dtn tr`lfymkr`iks gdibgtty gm`is

LF[MN]K YQGD]_NQY

LF[Y1 (f`vkr, pgdmrkgs)

LF[Y9, `dsuf`d skds`t`vk trgdspnrtkr (jusmfk, gi`pnsk t`ssuk)

7/26/2019 Hormonal Secretion of Pancreas

13/17

LF[Y= (arg`d)

LFPMNLKD ]PDYCK]@]

]cnrt tkrj stnrglk nb lfumnsk

Gmt`vgtks lfymnlkd sydtcgsk @dc`a`t lfymnlkd pcnspcnryfgsk

Lfymnfys`s `s gfsn st`jufgtki ay `dsuf`d

F`pnlkd`m gdi gdt`f`pnfyt`m

@dsuf`d prnjntks f`pnlkdks`s gdi `dc`a`ts f`pnfys`sn _rnjntks bnrjgt`nd nb -lfymkrnf pcnspcgtk gdi bgtty gm`i

sydtcks`sn ]t`jufgtks bgtty gm`i sydtcgsk (BG])n @dc`a`ts cnrjndk skds`t`vk f`pgsk (C]F)n Gmt`vgtks f`pnprntk`d f`pgsk (F_F)

_rntk`d ]ydtcks`s gdi Iklrgigt`nd

@dsuf`d prnjntks prntk`d gmmujufgt`nd8

]t`jufgtks gj`dn gm`i uptgek

@dmrkgsks tck gmt`v`ty nb prntk`d sydtcks`s

@dc`a`ts prntk`d iklrgigt`nd

GMY@ND NB @D][F@D ND F@RKQ8

GMY@ND NB @D][F@D ND BGY

7/26/2019 Hormonal Secretion of Pancreas

14/17

GMY@ND NB @D][F@D ND J[]MFK

7/26/2019 Hormonal Secretion of Pancreas

15/17

@D][F@D GMY@ND (][JJGQP)8

Inj`dgtks `d Bki ]tgtk Jktganf`sj.

lfumnsk uptgek `d jnst mkffs

lfumnsk usk & stnrglk

prntk`d sydtcks`s

bgt sydtcks`s

I@GAKYK] JKFF@Y[]

7/26/2019 Hormonal Secretion of Pancreas

16/17

I@GAKYK] JKFF@Y[]`s g sydirnjk nb `jpg`rki

mgrancyirgtk, bgt, gdi prntk`d jktganf`sjmguski ay k`tckrfgme nb `dsuf`d skmrkt`nd nr ikmrkgski skds`t`v`ty nb tckt`ssuks tn `dsuf`d.

Y\N LKDKQGF YP_K]8

n Yypk @ i`gaktks,`dsuf`d-ikpkdikdt i`gaktks jkff`tus

(@IIJ)8

Mguski ay fgme nb `dsuf`d skmrkt`nd.

7/26/2019 Hormonal Secretion of Pancreas

17/17

n Yypk @@ i`gaktks,dnd`dsuf`d-ikpkdikdt i`gaktks

jkff`tus (D@IIJ)8n Mguski ay ikmrkgski skds`t`v`ty nb tgrlkt t`ssuks tn tck

jktganf`m kbbkmt nb `dsuf`d. Yc`s rkiumki skds`t`v`ty tn `dsuf`d`s nbtkd mgffki `dsuf`d rks`stgdmk.

^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^