Hoodia gordonii - Amherst College · • many supplements claim to have hoodia in them, markeng the...
Transcript of Hoodia gordonii - Amherst College · • many supplements claim to have hoodia in them, markeng the...
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HoodiagordoniiByStacyBrossy
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• GeneralInfo• Medicinaluses– Appe7tedepressant
• Howitworks• History• Problemswithmakingintoadietsupplement
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Basics:• Apocynaceae,milkweedfamily,
knownforproducingpoisonouslatex.
• Othernames:xhoobaorghaap• Kalaharisemi‐desertsofSouth
Africa,Botswana,Namibia,andAngola.
Lookslikeacactus,spinywatercollec7ngsucculentstems
Takes3yrstoreachmaturity
Livesfor15‐25yrs
Producesfleshcoloredflowersthatsmelllikedecayingmeat,aPractfliesthatpollinateit.
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• ItwasusedforthousandsofyearsbytheSanBushmenpeople
• Appe$tedepressantandthirstquencher– indiges7onproblems– severeabdominalcramps
– Indiges7on– tuberculosis– hypertension– diabetes– smallinfec7ons
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P57
• Makesasteroidalglycosidethataffectsthecentralnervoussystemmessengers.
• Neuropep7tesreadtheglycosideasacompactversionofglucosesothebrainreceivesamessagethatenoughfoodhasbeeneaten
• Causesappe7tereceptorstoturnoff,nomorehungerpains.
• Studiesshowpeopletakingsmallamountsofitover4weekswereconsumingaround1000lesscaloriesperdayandsignificantweightloss
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• hPp://www.diethelper.co.uk/images/diagram.gif
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Whycan’tIgetsome?• P57wasisolatedbyaSouthAfricanCouncilforScien7ficResearch(CSIR)labin1997
• SoldapatentforP57toPhytopharm,pharmaceu7calcompanyintheUK
• Teamedupw/PfizerandUnilevertomakeanan7‐obesitydrugbutranintoproblems– Thereisn’tenoughinAfricatoharvest– Couldn’tsynthesizeit– Hardtocul7vate– Possiblycausesharmtotheliver
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Americansspendabout30billiondollarsonweightloss
• Supplementscams• manysupplementsclaimtohavehoodiainthem,marke7ngthe
naturalnessandthebenefitsthattheSanpeoplearesupposedlygeang
• 80%don’thaveanyhoodiainthem
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In2002CSIRofficiallyrecognizedtheSanpeople’srightsoverHoodiasotheycouldgetapercentageoftheprofitsfromanydrugsmadefromit,butthedrughasn’tbeenmadeandmostmoneydoesn’tmakeitbackbecauseoflegali7es.