HIV genome map

This genetic map of the HIV-1 viral genome depicts the structural and regulatory genes in their relative position as well as their products and functions.- The remaining genes (vif, vpr, vpu, rev and nef) are regulatory genes whose products play critical roles in controlling viral expression of viral gene products within the infected cell.-The rev-responsive element (RRE) is the binding site for the rev gene product which transport RNA massage from the nucleus

HIV-1 and related Retroviruses

Primate lentiviruses

There are three major species of African green monkeys

Studies of the African green monkey and their related simian virus (SIVagm)yield important informationin our understanding of HIV-1 and HIV-2.

Geographic domain of African green monkeys

This map of Africaindicates the native locations of different species of the African green monkey.Within each species, a unique family of SIVagm has been show to exist.

Phylogenic differences of SIVagm

When the SIVagm from different species of African green monkeys are genetically mapped the phylogenic tree demonstrates unique clustering of SIVagm based on the species was obtained.

Subgroups of SIV

SIVagm has several subspecies bas on the species of African green monkey