Hillman CV Aug 2018 - Stanford UniversityD’Arceuil HE, Mandeville JB, Marota JJA, Rosen BR, Liu...

Curriculum Vitae

Date: August 2018

Elizabeth M. C. Hillman

Professor of Biomedical Engineering and Radiology

Zuckerman Mind Brain Behavior Institute and Kavli Institute for Brain Sciences

Columbia University, New York, NY 10027

Website: www.bme.columbia.edu/~hillman Telephone: 917 207 0008, E-mail: [email protected]

Fields of Specialization: As a physicist by training, my research program combines the development of novel imaging and microscopy tools with multidimensional data analysis, and the application of these tools to understanding the living brain. My multi-scale biomedical imaging and microscopy techniques include SCAPE microscopy (licensed to Leica Microsystems), wide-field optical mapping in awake behaving mice (WFOM) and a range of two-photon and dynamic imaging approaches as well as analysis methods that leverage spatiotemporal and spatiospectral unmixing. My scientific contributions have focused on elucidating the mechanistic relationship between blood flow and neuronal activity in the living brain (neurovascular coupling), and have more recently extended to studying awake, whole-brain neural activity across species from Drosophila and zebrafish to mice and humans.

Academic Training School Degree Date University College London Physics, MSci (equivalent to BSc + MSc) 1998 University College London Medical Physics and Bioengineering, Ph.D. 2002

MS Dissertation: “Application of time-series analysis techniques to physiological data” Sponsors: Prof Clare Elwell and Prof David Miller

Ph.D. Dissertation: “Experimental and theoretical investigations of near infrared tomographic imaging methods and clinical applications” (published) Sponsors: Prof Jeremy Hebden and Prof David Delpy FRS

Career History: Employer Position Beginning Ending Columbia University Professor in Biomedical Engineering 06/17 Present Columbia University Professor in Radiology 06/17 Present Columbia University Tenured Assoc Professor in Biomedical Engineering 02/13 06/17 Columbia University Tenured Associate Professor in Radiology 02/13 06/17 Columbia University Associate Professor in Biomedical Engineering 07/11 02/13 Columbia University Associate Professor in Radiology 07/11 02/13


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Columbia University Assistant Professor in Biomedical Engineering 07/06 06/11 Columbia University Assistant Professor in Radiology 07/06 06/11 Harvard Medical School Instructor in Radiology 06/05 06/06 Mass General Hospital Assistant Physicist, Department of Radiology 06/05 06/06 Mass General Hospital / Harvard Medical School

Post-Doctoral Research Fellow, Martinos Center for Biomedical Imaging

04/03 06/05

Argose Inc. Waltham Manager of In-vivo Spectroscopy 02/02 01/03

Awards Received:

2017 SPIE 2018 Biophotonics Technology Innovator Award. 2016 Elected Fellow, American Institute for Medical and Biological Engineering (AIMBE). 2016 Elected Fellow, Society of Photonics in Industry and Engineering (SPIE). 2015 Elected Fellow, Optical Society of America (OSA). 2013 Designated a ‘Rising Star’ by the Optical Society of America (OSA). 2012 National Academy of Engineering (NAE) Frontiers Symposium. 2011 Adolph Lomb Medal from the Optical Society of America (OSA) for contributions to

Optics before the age of 35. 2010 NSF CAREER Award. 2008 Rodriguez Junior Faculty Award, Columbia University School of Engineering and

Applied Sciences. 2007 Human Frontier Science Program (HFSP) Young Investigator Award. 2006 Wallace H Coulter Foundation Early Career Award. 1998-02 Wellcome Trust Prize Studentship (funding PhD work; stipend and research costs). 1998 UCL Prize for top overall undergraduate in Physics and Astronomy, Dean’s List,

University College London, UK. 1997 Top Physics and Astronomy Undergraduate 3rd year, University College London. 1996 Top Physics and Astronomy Undergraduate 2nd year, University College London. 1995 Top Physics and Astronomy Undergraduate 1st year, University College London.

Travel and early training awards 2006 OSA BIOMED Conference Travel Award 2005 Brain 2005 ISCBFM Conference Travel Award 2004 Brain Blood Flow and Metabolism Gordon Conference Travel Award 2001 SPIE Photonics West Travel Award 2000 Outstanding Short Paper Award, Rank Prize Fund symposium on applications of fast

low-level light detection 2000 Best Poster Award, Gordon Research Conference: Lasers in Medicine and Biology 2000 Lasers in Medicine and Biology Gordon Conference Travel Award. 2000 OSA BIOMED Travel Award

Current Professional Organization Membership: 2016- Fellow, American Institute for Medical and Biological Engineering (AIMBE) 2016- Fellow, Society of Photonics in Industry and Engineering (SPIE) 2015- Fellow, Optical Society of America (OSA) 2014- Member, American Heart Association 2013- Member, Society for Brain Mapping & Therapeutics (SBMT)


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2005- Member, International Society for Cerebral Blood Flow and Metabolism (ISCBFM) 2005- Member, Society for Neuroscience (SFN) 1998- Member, Society of Photonics in Industry and Engineering (SPIE) 1998- Member, Optical Society of America (OSA) 1998-03 Member, American Association of Physicists in Medicine (AAPM)

Publications

Citation Metrics (as of 08/19/2018) Google Scholar: Sum of the Times Cited: 6,128; h-index: 38

Papers in Refereed Journals:

(* indicates mentored student / fellow; underline bold indicates Hillman as senior author)

J1) Elwell CE, Springett R, Hillman EMC, Delpy DT. Oscillations in cerebral haemodynamics - Implications for functional activation studies. Adv Exp Med & Biol. 1999; 471: 57-65.

J2) Hebden JC, Schmidt FEW, Fry ME, Schweiger M, Hillman EMC, Delpy DT, Arridge SR. Simultaneous reconstruction of absorption and scattering images using multi-channel measurement of purely temporal data. Opt Lett. 1999; 24 (8): 534-6.

J3) Schmidt FEW, Fry ME, Hillman EMC, Hebden JC, Delpy DT. A 32-channel time-resolved instrument for medical optical tomography. Rev Sci Instrum. 2000; 71 (1): 256–65.

J4) Arridge SR, Hebden JC, Schweiger M, Schmidt FEW, Fry ME, Hillman EMC, Dehghani H. A method for 3D time-resolved optical tomography. J Imaging Syst Technol. 2000; 11: 2-11.

J5) Schmidt FEW, Hebden JC, Hillman EMC, Fry ME, Schweiger M, Delpy DT. Multiple slice imaging of a tissue-equivalent phantom using time-resolved optical tomography. Appl Opt. 2000; 39 (19): 3380-7.

J6) Hillman EMC, Hebden JC, Schmidt FEW, Arridge SR, Schweiger M, Dehghani H, Delpy DT. Calibration techniques and datatype extraction for time-resolved optical tomography. Rev Sci Instrum. 2000; 71 (9): 3415-27.

J7) Hillman EMC, Hebden JC, Schweiger M, Dehghani H, Schmidt FEW, Delpy DT, Arridge SR. Time resolved optical tomography of the human forearm. Phys Med Biol. 2001; 46 (4): 1117-30. (Top 10 most downloaded PMB paper of 2000)

J8) Hebden JC, Veenstra H, Dehghani H, Hillman EMC, Schweiger M, Arridge SR, Delpy DT. Three dimensional time-resolved optical tomography of a conical breast phantom. Appl Opt. 2001; 40 (19): 3278-87.

J9) Hebden JC, Gibson A, Yusof R, Everdell N, Hillman EMC, Delpy DT, Arridge SR, Austin T, Meek JH, Wyatt JS. Three-dimensional optical tomography of the premature infant brain. Phys Med Biol. 2002; 47 (23): 4155-66.


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J10) Hebden JC, Gonzalez FM, Gibson A, Hillman EMC, Yusof R, Everdell N, Delpy DT, Zaccanti G, Martelli F. Assessment of an in situ temporal calibration method for time-resolved optical tomography. J Biomed Opt. 2003; 8: 87-92.

J11) Corlu A, Durduran T, Choe R, Schweiger M, Hillman EMC, Arridge SR, Yodh AG. Uniqueness and wavelength optimization in continuous-wave multispectral diffuse optical tomography. Opt Lett. 2003; 28 (23): 2339-41.

J12) Hillman EMC, Boas DA, Dale AM, Dunn AK. Laminar optical tomography: demonstration of millimeter-scale depth-resolved imaging in turbid media. Opt Lett. 2004; 19 (14): 1650-2.

J13) Zhang Q, Brukilacchio TJ, Li A, Stott JJ, Chaves T, Hillman EMC, Wu T, Chorlton MA, Rafferty E, Moore RH, Kopans DB, Boas DA. Co-registered Tomographic X-ray and Optical Breast Imaging: Initial Results. J Biomed Opt. 2005; 10 (2): 024033.

J14) Corlu A, Choe R, Durduran T, Lee K, Schweiger M, Arridge SR, Hillman EMC, Yodh AG. Diffuse optical tomography with spectral constraints and wavelength optimization. Appl Opt. 2005; 44 (11): 2082-2093.

J15) Li A, Boverman G, Zhang Y, Brooks D, Miller EL, Kilmer ME, Zhang Q, Hillman EMC, Boas DA. An optimal linear inverse solution given multiple priors in diffuse optical tomography. Appl Opt. 2005; 44 (10): 1948-1956.

J16) *Custo A, Wells WM, Barnett AH, Hillman EMC, Boas DA. Effective Scattering Coefficient of the Cerebral Spinal Fluid in Adult Head Models for Diffuse Optical Imaging, Appl Opt. 2006; 45(19): 4747-4755.

J17) Devor A, Tian P, Nishimura N, Teng IC, Hillman EMC, Narayanan SN, Ulbert I, Boas DA, Kleinfeld D, Dale AM. Suppressed neuronal activity and concurrent arteriolar vasoconstriction may explain negative BOLD, J Neurosci. 2007; 27(16): 4452-4459.

J18) Hillman EMC, Devor A, *Bouchard M, Dunn AK, Krauss GW, Skoch J, Bacskai J, Dale AM, Boas DA. Depth-resolved Optical Imaging and Microscopy of Vascular Compartment Dynamics During Somatosensory Stimulation, NeuroImage 2007, 35(1): 89-104.

J19) Hillman EMC. Optical Brain Imaging In-vivo: Techniques and Applications from Animal to Man, (Invited Review), J Biomed Opt. 2007, 12, 051402. (Invited Review) *Also selected to appear in the “Virtual Journal of Biological Physics Research”

J20) Hillman EMC, Bernus O, *Pease E, *Bouchard MB. Pertsov A. Depth-resolved optical imaging of transmural electrical propagation in perfused heart, Optics Express, 15 (26), 2007, 17827-17841. *Also selected to appear in the “Virtual Journal of Biomedical Optics” (cover).

J21) Hillman EMC, Moore A. All-optical anatomical co-registration for molecular imaging of small animals using dynamic contrast, Nature Photonics. 2007, 1(9): 526-530. (Cover article, ‘Meet the Author’ Interview and ‘News and Views’ feature. Selected to be free online as a ‘Highlight of 2007’).

J22) *Radosevich AJ, *Bouchard MB, *Burgess SA, *Chen BR, Hillman EMC. Hyper-spectral in-vivo two-photon microscopy of intrinsic contrast, Optics Letters, 2008, 33 (18), 2164-2166. *Also selected to appear in the “Virtual Journal of Biological Physics Research” and the “Virtual Journal of Biomedical Optics” (cover)


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J23) *Burgess SA, *Bouchard MB, *Yuan B, Hillman EMC. "Simultaneous Multi-Wavelength Laminar Optical Tomography, Optics Letters, 2008, 33 (22), 2710-2712.

J24) Devor A, Hillman E. M. C, Tian P, Waeber C, Teng I. C, Ruvinskaya S, Shalinsky M, Zhu H, Haslinger R, Narayanan S, Ulbert I, Dunn A. K, Lo E, Rosen B. R, Dale A. M, Kleinfeld D, Boas D. A, Stimulus-induced changes in blood flow and 2-deoxyglucose uptake dissociate in ipsilateral somatosensory cortex, J. Neurosci, 2008, 28: 14347-14357.

J25) Hillman EMC, *Burgess SA. Sub-millimeter 3D Optical Imaging of Living Tissue using Laminar Optical Tomography, Laser & Photonics Reviews, 2009, 3 (1-2), 159-180. (Invited)

J26) Karagiannis A, Gallopin T, Dávid C, Battaglia D, Geoffroy H, Rossier J, Hillman EMC. Staiger J, Cauli B. Classification of NPY-expressing neocortical interneurons, J Neurosci, 2009, 29(11):3642-3659.

J27) Blaner WS, O’Byrne SM, Wongsiriroj N, Kluwe J, D’Ambrosio D, Jiang H, Schwabe RF, Hillman EMC, Piantedosi R, Libien J. Hepatic Stellate Cell Lipid Droplets: A Specialized Lipid Droplet for Retinoid Storage. Biochimica et Biophysica Acta, 2009, 1791(6):467-73.

J28) *†Yuan B, *†Burgess SA, *Iranmahboob AK, *Bouchard MB, *Lehrer N, *Bordier C, Hillman EMC, System for rapid, simultaneous, high resolution, depth-resolved fluorescence and absorption optical imaging, Rev. Sci. Instrum. 2009, 80, 043706-1. †Equal contribution first authors.

J29) Culver JP, Drexler W, Drezek RA, Georgakoudi I, Hillman EMC, Richards-Kortum R, Topics in Biomedical Optics: introduction to the feature issue, Appl. Opt, 2009, 48 (10), pp. TBO1-TBO2. (Invited)

J30) *†Bouchard MB, *†Chen BR, *Burgess, SA, Hillman EMC, “Ultra-fast multispectral optical imaging of cortical oxygenation and blood flow dynamics”, Optics Express, 2009, 17 (18), 15670-15678. †Equal contribution first authors.

J31) Sirotin YB, †Hillman EMC, *Bordier C, Das A. “Spatiotemporal precision and hemodynamic mechanism of optical point-spreads in alert primates”, PNAS, 2009, 106, 18390-18395. (Top 30 downloaded papers for PNAS 2009, featured as Nature ‘Best of Research Highlights’ for 2009). †co-senior author.

J32) *Sun R, *Bouchard MB, Hillman EMC “SPLASSH: Open source software for camera-based high-speed, multispectral in-vivo optical image acquisition” Biomed Opt Expr, 2010, 1 (2), 385-397.

J33) Tian P, Teng IC, May LD, Kurz R, Lu K, Scadeng M, Hillman EMC, De Crespigny AJ, D’Arceuil HE, Mandeville JB, Marota JJA, Rosen BR, Liu TT, Boas DA, Buxton R, Dale AM, Devor A, “Cortical depth-specific microvascular dilation underlies laminar differences in blood oxygenation level-dependent functional MRI signal”, PNAS, 2010, 107 (34), 15246-15251.

J34) *Burgess SA, Ratner D, *Chen BR, Hillman EMC, “Fiber-Optic and Articulating Arm Implementations of Laminar Optical Tomography for Clinical Applications” Biomed Opt Expr, 2010, 1 (3), 780-790.


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J35) Nordstrom RJ, Almutairi A, Hillman EMC, “Feature Issue Introduction: Bio-Optics in Clinical Applications, Nanotechnology, and Drug Discovery”, Biomed Opt Expr, 2010, 1 (3) 746-747 (Invited)

J36) Taber KH, Hillman EMC, Hurley RA, “Optical Imaging: A New Window to the Adult Brain”, Neuropsychiatry Clin Neurosci 2010, 22 (4), 357-360 (Invited) (cover)

J37) Baik AD, Lu XL, Qiu J, Huo B, Hillman EMC, Dong C, Guo XE, “Pseudo-3D Cytoskeletal Dynamics of Osteocytes under Fluid Flow”, Biophys J, 2010, 99 (9), 2812-2820.

J38) *Chen BR, *Bouchard MB, *McCaslin AFH, *Burgess SA, Hillman EMC, “High-speed vascular dynamics of the hemodynamic response”, Neuroimage, 2011, 54 (2), 1021-1030.

J39) *McCaslin AFH, *Chen BR, *Radosevich AJ, Cauli B, Hillman EMC “In-vivo 3D morphology of astrocyte-vasculature interactions in the somatosensory cortex: implications for neurovascular coupling”, J Cereb Blood Flow Metab, 2011, 31, 795–806 (Feature and Cover article).

J40) *Grosberg LE, *Radosevich AJ, Asfaha S, Yang X, Wang TJ, Hillman EMC, “Spectral characterization and unmixing of intrinsic contrast in intact normal and diseased gastric tissues using hyperspectral two-photon microscopy” PlosOne 2011, 6(5): e19925.

J41) Hillman EMC, *Amoozegar CB, *Wang T, *McCaslin AFH, *Bouchard MB, Mansfield JR, Levenson RM, “In-vivo optical imaging and dynamic contrast methods for biomedical research” Phil. Trans. Royal Soc A. 2011, 369 (1955), 4620-4643 (Invited)

J42) Chen L, Chan TH, Choyke PL, Hillman EMC, Bhu-jwalla ZM, Chi CY, Wang G, Szabo Z, Wang, Y, “A Signal Deconvolution Tool for In Vivo Dynamic Contrast-enhanced Imaging of Complex Tissues”, Bioinformatics 2011, 27(18): 2607-2609 .

J43) Hillman EMC, Elson DS, Bigio IJ, Levenson RM, So PTC. “Feature Issue Introduction: Advances in Optics for Biotechnology, Medicine and Surgery” Biomed Opt Expr, 2012, 3(3): 531–532.

J44) Qiu J, Baik AD, Lu L, Hillman EMC, Zhuang Z, Dong C, Guo XE, “Theoretical Analysis of Novel Quasi-3D Microscopy of Cell Deformation”, Cel. Mol. Bioeng 2012, 5 (2), 165-172.

J45) *Muldoon T, *Burgess SA, *Chen BR, Ratner D, Hillman EMC, “Analysis of skin lesions using Laminar Optical Tomography”, Biomed Opt Expr, 2012. 3(7): p. 1701-1712.

J46) *Grosberg LE, *Chen BR, Hillman EMC, “Simultaneous multi-plane in-vivo non-linear microscopy using spectral encoding”, Optics Letters, 2012, 37(14), 2967-2969.

J47) *Amoozegar CB, *Wang T, *Bouchard MB, *McCaslin AFH, Blaner WS, Levenson RM, Hillman EMC, “Dynamic contrast enhanced optical imaging of in-vivo organ function”, J Biomed Opt, 2012, 17(9), 096003.

J48) Baik AD, Qiu J, Hillman EMC, Dong C, Guo XE, “Simultaneous Tracking of 3D Actin and Microtubule Strains in Individual MLO-Y4 Osteocytes under Oscillatory Flow”, Biochem. Biophys. Res. Comms, 2013, 431(4):718-23.


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J49) *Kozberg M, *Chen BR, *De Leo SE, *Bouchard MB, Hillman EMC, “Resolving the transition from negative to positive BOLD in the developing brain”, PNAS 2013, 110(11):4380-5.

J50) Baik AD, Qiu J, Hillman EMC, Dong C, Guo XE. Simultaneous tracking of 3D actin and microtubule strains in individual MLO-Y4 osteocytes under oscillatory flow. Biochemical and Biophysical Research Communications. 2013;431:718-723

J51) Hillman EMC, & *Kozberg M. G. “What secrets can functional MRI reveal about the developing infant brain?” (invited editorial), Imaging in Medicine 5, 203-206, (2013).

J52) *Rayshubskiy A, Wojtasiewicz TJ, Mikell CB, *Bouchard MB, *Timerman D, Youngerman BE, McGovern RA, Otten ML, Canoll, PD, McKhann II GM, Hillman,EMC. "Direct, intraoperative observation of ~0.1 Hz hemodynamic oscillations in awake human cortex: Implications for fMRI." NeuroImage, 87, 323-331, (2014).

J53) Qiu J, Baik AD, Lu XL, Hillman EMC, Zhuang Z, Dong C, Guo XE. A noninvasive approach to determine viscoelastic properties of an individual adherent cell under fluid flow. Journal of Biomechanics, 47 (6), 1537-1541 (2014).

J54) Cayce JM, *Bouchard MB, Chernov MM, *Chen BR, *Grosberg LE, Jansen ED, Hillman EMC, Mahadevan-Jansen A. "Calcium imaging of infrared-stimulated activity in rodent brain", Cell Calcium, 55 (4), 183-190 (2014).

J55) Hillman, EMC (2014). Coupling Mechanism and Significance of the BOLD Signal: A Status Report. Annual Review of Neuroscience, 37: 161-181 (2014).

J56) *Chen BR, *Kozberg M, *Bouchard MB , *Shaik MA and Hillman EMC, “A critical role for arterial endothelium in neurovascular coupling”, JAHA, 3: e000787, (2014).

J57) Hillman EMC, ‘Out for Blood’, Scientific American MIND, July/Aug (2014).

J58) Chen L, Choyke PL, Wang N, Clarke R, Bhujwalla ZM, Hillman EMC, Wang G, and Wang Y, Unsupervised deconvolution of dynamic imaging reveals intratumor vascular heterogeneity and repopulation dynamics. PLoS One, 9(11): p. e112143, (2014).

J59) *Bouchard MB, Voleti V, Mendes C, Lacefield C, Grueber W, Mann R, Bruno R, Hillman EMC, “Swept Confocally Aligned Planar Excitation (SCAPE) microscopy for fast, volumetric microscopy of behaving organisms”, Nature Photonics, 9, 113–119 (2015). (Cover article, ‘News and Views’ feature. Research Highlight in Nature Methods).

J60) *Galwaduge PT, *Kim SH, *Grosberg LE, Hillman EMC, "Simple wavefront correction framework for two-photon microscopy of in-vivo brain," Biomed. Opt. Express 6, 2997-3013 (2015).

J61) Lacroix A, Toussay X, Anenberg E, Lecrux C, Ferreiros N, Karagiannis A, Plaisier F, Chausson P, Jarlier F, *Burgess SA, Hillman EMC, Tegeder I, Murphy TH, Hamel E, and Cauli B, “COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex.” J Neurosci, 35(34): p. 11791-810. (2015).

J62) Pavone FS, Hillman EMC, Leblond F, Shoham S, “Introduction to the Optics and the Brain 2015 feature issue”, Biomedical Optics Express, 6 (12), pp. 4992-4993 (2015).


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J63) Akassoglou K, Agalliu D, Chang CJ, Davalos D, Grutzendler J, Hillman EMC, Khakh BS, Kleinfeld D, McGavern DB, Nelson SJ and Zlokovic BV, “Neurovascular and Immuno-Imaging: From Mechanisms to Therapies. Proceedings of the Inaugural Symposium”, Front. Neurosci., 10, (2016)

J64) *Chow DS, Horenstein CI, Canoll PD, Lignelli A, Hillman EMC, Filippi CG, Grinband J, “Glioblastoma Induces Vascular Dysregulation in Non-Contrast Enhancing Peritumoral Regions in Humans”, Am J Radiol, 206(5):1073-81 (2016).

J65) *Kozberg MG, *Ma Y, *Kim SH, Hillman EMC, ‘Rapid postnatal expansion of neural networks occurs in an environment of altered neurovascular and neurometabolic coupling’, J Neurosci, 36(25): p. 6704-17 (2016)

J66) *Ma Y, *Shaik MA, *Kim SH, *Kozberg MG, *Thibodeaux DN, *Zhao HT, *Yu H., and Hillman EMC, ‘Wide-field optical mapping of neural activity and brain haemodynamics: considerations and novel approaches’. Philos Trans R Soc Lond B Biol Sci. 371 p. 1705 (2016).

J67) Lunardi C.N., Gomes A.J.,* Palepu S., *Galwaduge P.T., and Hillman E.M.C, ‘PLGA nano/microparticles loaded with cresyl violet as a tracer for drug delivery: Characterization and in-situ hyperspectral fluorescence and 2-photon localization’. Materials Science and Engineering: C, 70, Part 1: p. 505-511. (2017)

J68) *Kozberg MG, Hillman EMC, "Neurovascular coupling develops alongside neural circuits in the postnatal brain", Neurogenesis, 3(1): p. e1244439 (2016).

J69) *Ma Y, *Kozberg MG, Hillman EMC, ‘Resting-state hemodynamics are spatiotemporally coupled to synchronized and symmetric neural activity in excitatory neurons’, PNAS, 113 (52) E8463–E8471 (2016).

J70) Tang M, Gao G, Rueda CB, Awano T, Engelstad KM, Sanchez-Quintero M-J, Yang H, Li F, Li H, Su Q, Shetler KE, Jones L, McConathy J, *Thibodeaux DN, *Yu H, Seo R, Hillman EMC, Noebels JL, De Vivo DC, Monani UR, “Brain microvasculature defects and Glut1-deficiency syndrome averted by early repletion of the Glucose Transporter-1 protein”, Nature Communications, 8:14152. (2017).

J71) Marcu L and Hillman EMC. In vivo Optical Imaging / Intravital Microscopy. J Biophotonics,10(6-7):760-1. doi: 10.1002/jbio.201770066. (2017)

J72) Nguyen HD, Ullmann JFP, McLachlan GJ, *Voleti V, *Li W, Hillman EMC, Reutens DC, Janke AL, “Whole‐volume clustering of time series data from zebrafish brain calcium images via mixture modeling”, The ASA Data Science Journal. 2018;11(1):5-16.

J73) *Shaik MA, Hillman EMC, “Skip the salt: your brain might thank you”, Nature Neuroscience 21 (2), 154 (2018) News and Views.

J74) Miller J, Wang ST, Orukari I, Prior J, Sudlow G, Su X, Liang K, Tang R, Hillman EMC, Weilbaecher KN, Culver JP, Berezin MY, Achilefu S. Perfusion-based fluorescence imaging method delineates diverse organs and identifies multifocal tumors using generic near-infrared molecular probes. J Biophotonics. 11(4):e201700232 (2018)

J75) Hillman EMC, *Voleti V, *Patel K, *Li W, *Yu H, *Perez-Campos C, *Benezra SE, Bruno RM, *Galwaduge PT. “High-speed 3D imaging of cellular activity in the brain using axially-extended beams and light sheets”. Curr Opin Neurobiol. 50:190-200. (2018)


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Manuscripts Under Review / in revision

1) *Rebecca Vaadia†, *Li W†, Singhania A†, *Voleti V, Galindo S†, Lei Y-T, Lee JK, Lee KL, Carpenter N, Costantini D, Hillman EMC, Grueber WB, “Proprioceptive neuron dynamics in freely crawling Drosophila larvae”, in revision (2018)

2) *Xu L, *Li W, *Voleti V, Hillman EMC, Stuart Firestein, ‘Widespread inhibition in peripheral olfactory encoding observed using high-speed volumetric microscopy of intact epithelium.’ in revision (2018)

Manuscripts in Preparation

1) *Thibodeaux DN, *Kim SH, *Shaik MA, *Ma Y, Hillman EMC, ‘Audiovisualization of multivariate neuroimaging data’, (in preparation)

2) *Shaik MA, *Ma Y, *Portes JP, *Kim SH, *Thibodeaux DN, *Voleti V, *Kozberg MG, Hillman EMC, ‘Selective perturbation of neurovascular coupling reveals dual endothelial mechanisms’, (in preparation)

3) *Voleti V, *Li W, *Patel KB, *Perez-Campos C, *Bouchard MB, Targoff K, Hillman EMC, ‘A next-generation SCAPE microscope for high-speed 3D microscopy’, (in preparation)

4) *Zhao TH, *Chow D, *Kozberg MG, *Kim SH, Hillman EMC, ‘Mapping of neural function and neurovascular coupling during acute stroke’, JCBFM (in preparation).

5) *Li W, Mishra N, Schaffer E, *Voleti V, Axel R, Hillman EMC, “High –speed volumetric imaging of the behaving adult fly brain”, (in preparation)

6) *Portes JP, *Amoozegar CB, *Shaik M, *Chen BR, *Kozberg M, Hillman EMC, ‘Non-linear modeling of the hemodynamic response function based on endothelial neurovascular coupling’, (in preparation)

7) *Kim S, *Voleti V, *Ma, Y, *Ramirez E, *Timerman D, *Chen BR, *McCaslin A, *L’Heureux B, Hillman EMC, “Spatiotemporal properties of resting state neural network activity”, (in preparation)

8) *Montgomery MK, *Kim SH, Dovas T, Chow D, *Kozberg MG, *Shaik MA, *Patel KB, *Ma Y, Schevon C, Canoll P and Hillman EMC, “Neurovascular and functional imaging of glioma progression”, (in preparation)

9) Hillman EMC, “Light sheet microscopy in neuroscience”, Annual Reviews Neuroscience, 2018 (in preparation)

Refereed Proceedings of Conferences: (List in Chronological Order)

C1) Hillman EMC, Dehghani, H, Hebden JC, Arridge SR, Schweiger M, Delpy DT. "Differential imaging in heterogeneous media: limitations of linearization assumptions", in Proc SPIE 4250, p. 327-338. 2001.

C2) Dehghani H, Hillman EMC, Schweiger M, Arridge SR, Delpy DT. "Optical tomography of a 3D multilayered head model”. Proc SPIE 4250, p. 45-52. 2001.

C3) Riley JD, Arridge SR, Chrysanthou Y, Dehghani H, Hillman EMC, Schweiger M. “The Radiosity Diffusion Model in 3D”. Proc SPIE 4431, p. 153-164. 2001.


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C4) Hillman EMC, Devor A, Dale AM, Dunn AK, Boas DA. “The use of depth-resolved optical imaging to separate cortical vascular compartments during functional activation”. J Cereb Blood Flow & Metab. 2005; 25: S374.

C5) Hillman EMC, Devor A, Dunn AK, Boas DA. “Laminar optical tomography: high-resolution 3D functional imaging of superficial tissues”. Proc. SPIE 6143, 61431M, 2006.

C6) Hillman EMC, Devor A, Boas DA. “High Resolution Functional Optical Imaging of Living Tissues”. IEEE Proceedings of the International Symposium on Biomedical Imaging (ISBI), Arlington VA, April 2006.

C7) Hillman EMC, *Bouchard M, Devor A, De Crespigny A, Boas DA. “Functional optical imaging of brain activation: a multi-scale, multi-modality approach”. IEEE Proceedings of the Life Science Systems and Application Workshop, Bethesda MD, July 2006.

C8) *Burgess SA, *Yuan B, *Radosevich AJ, *Bouchard MB, Hillman EMC. “High-resolution 3D optical imaging of tissue”, IEEE Proceedings LEOS, 2007.

C9) Mahadevan-Jansen A, Cayce JM, Friedman R, Roe AW, Konrad PE, Hillman E, Jansen E. “Imaging optically induced neural activity in the brain”.Conf Proc IEEE Eng Med Biol Soc. 3379-81. (2010)

C10) Cayce JM, *Bouchard M, *Chen B, Jansen ED, Hillman EMC, Mahadevan-Jansen A. “Optical imaging of signals evoked by infrared neural stimulation of the rat brain”. Proc SPIE paper 7883G-146 (2011)

C11) Stoyanov D, Rayshubskiy A, Hillman EMC, “Robust registration of multispectral images of the cortical surface in neurosurgery'', IEEE ISBI, May 2012, Barcelona, Spain.

C12) Hillman EMC, Bouchard MB, Voleti V, Li W, Mendes CS, Lacefield CO, George V, Grueber WB, Mann RS, Bruno RM and Targoff K, “Swept Confocally-Aligned Planar Excitation (SCAPE) Microscopy for High Speed Volumetric Imaging in Behaving Animals”, Microscopy and Microanalysis, 21 (S3), August 2015, pp 413 – 414

Books and Chapters in Books: (List in Chronological Order)

B1) Hillman EMC. “Optical tomography”. Chapter in: ‘The Optics Encyclopedia; Basic Foundations and Practical Applications’. Brown ThG, Creath K, Kogelnik H, Kriss MA, Schmit J, Weber MJ, editors. Weinheim: (Wiley-VCH), 2003.

B2) *Burgess SA and Hillman EMC, “Laminar Optical Tomography”, Chapter in ‘Handbook of Biomedical Optics’. Eds: Boas DA, Pitris C, Ramanujam N. (Taylor & Francis), 2011

B3) *Kozberg MG and Hillman EMC, ‘Neurovascular coupling and energy metabolism in the developing brain’, Book Chapter in Prog Brain Res, 2016. 225: p. 213-42. New Horizons in Neurovascular Coupling: A Bridge Between Brain Circulation and Neural Plasticity (Elsevier).

B4) *Voleti V, Hillman EMC, ‘Single-Objective light sheet configurations’, Light Sheet Microscopy (Wiley), Eds Raynaud E, Tomancak P (in press)


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Patents (selected): 1) In-vivo Optical Imaging Method Including Analysis of Dynamic Images

Status: Issued 12/29/2015, filed 5/31/07, (US #9,220,411 B2) Inventor: Elizabeth M C Hillman. Status: Issued 12/29/2015, filed 5/31/07, (US #9,220,411 B2) Licensed by Cambridge Research & Instrumentation (CRi) (now PerkinElmer)

2) Laser-Scanning Intersecting Plane Tomography for high speed volumetric optical imaging. Status: Provisionals filed 12/04/09, (2413.115PRV), 04/13/10, (2413.121PRV)

Status: Full PCT application filed 12/04/10, (2413115US1) Status: Second PCT application filed 1/20/15, (PCT/US15/12076) Status: Additional PCT applications filed 2016- Inventor: Elizabeth M C Hillman and Matthew Bouchard* Status: Issued 12/31/2013, (US 20120140240 A1) Licensed to Leica Microsystems (field-exclusive for life-sciences applications)

3) Optical Imaging or Spectroscopy Systems and Methods Status: International, pending, filed 06/27/08, (PCT/US2008/008081)

Inventors: Elizabeth M C Hillman and Sean A. Burgess* Tools for multi-spectral and fluorescence depth-resolved imaging of living tissues. Licensed to Leica Microsystems (field-exclusive for life-sciences applications)

4) System and method for acquiring multiple depth planes simultaneously in microscopy. Status: Provisionals filed 12/17/10 (2413126PRV), 04/29/11 (2413126PV2)

Status: Full PCT application filed 12/16/11, (2413126WO1) Inventor: Elizabeth M C Hillman and Lauren E Grosberg* Multiplexing methods to allow high-speed volumetric imaging in laser scanning microscopy.

Consulting Activities: Firm Beginning Ending Spectral Sciences Inc. 03/10 03/11 Enumeral Biomedical Corp 03/13 04/15 Leica Microsystems 09/16 08/19

Major New Products, Processes, Designs, or Systems:

• DyCE – Dynamic Contrast-enhanced small animal molecular imaging. Published in Nature Photonics in 2007. Patent application (Massachusetts General Hospital) licensed to Cambridge Research & Instrumentation, SBIR awarded 2008. CRi was acquired by Caliper Life Sciences in 2010, which was then acquired by PerkinElmer in 2011. DyCE is now incorporated into software for all small animal imaging platforms now sold by PerkinElmer. DyCE technique was recognized as 6th in ‘Top 10 Innovations for Life Sciences’ in 2010 in The Scientist F1000 magazine. (http://www.perkinelmer.com/Catalog/Category/ID/DyCE%20Module ).

• SCAPE – Swept, confocally aligned planar excitation microscopy. Published in Nature Photonics in 2015. Patent issued. IP licensed to Leica Microsystems for benchtop life science applications. Continuing commercial development for clinical applications.


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Research Funding History

Career funding (direct+indirect) As PI: ~$14,775,572 (+$3.93M pending) Including student funding: ~$16,750,008 Including grants as co-PI: ~$25,145,090

Current Funding

Sponsor: National Institutes of Health, National Institute of Neurological Disorders and Stroke & National Institute of Mental Health.

Title: “SCAPE microscopy for high-speed in-vivo volumetric microscopy in behaving organisms”

Role: Principal Investigator: Hillman EMC (2 mo) Dates: 09/01/15-08/31/18 Amount: $1,830,000 ($1,230,000 direct) + $149,089 Supplement received October 2016 Reference: 5U01NS094296-01 (BRAIN Initiative) Sponsor: National Institutes of Health, National Institute of Neurological Disorders and Stroke. Title: “In-vivo optical imaging of neurovascular coupling and cerebral metabolism” Role: Principal Investigator: Hillman EMC (2 mo) Dates: 05/01/08-02/28/20 Amount: $3,200,000 ($2,200,000 direct) Reference: 1 R01 NS063226-06 Awarded on 1st review with 5.7th percentile score Competitive renewal 3rd percentile (score 16) + $120,507 supplement ($106,285 direct) in 2009 Sponsor: National Institute of Mental Health. Title “Decoding the neural basis of resting-state functional connectivity mapping” Role: Principal Investigator: Hillman EMC (2 mo) Dates: 09/01/17-08/31/21 Amount: $4,200,000 total Reference: 1 RF1 MH114276-01 (BRAIN Initiative) Sponsor: Simons Collaboration on the Global Brain Research Awards Title “The Representation of Internal State in the Fly Brain” Role: Principal Investigators: (Abbott L, Axel R, Rubin G, Ruta V, Aso Y, Hillman EMC) Dates: 09/01/17-08/31/22 Amount: $1,000,000 to Hillman ($3,875,000 total) Sponsor: National Institute of Neurological Disorders and Stroke Title “Computational and circuit mechanisms underlying motor control” Role: Principal Investigator: Costa R and Jessell T (Hillman co-I, 2.4 mo) Dates: 09/01/2017-08/31/2022 Amount: $15,916,093 total Reference: 1U19NS104649-01 (BRAIN Initiative) Sponsor: Kavli Foundation Title “Dream-Team” award Role: Principle Investigator: Hillman EMC Dates: 11/1/17- Amount: $25,000


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Sponsor: National Heart Lung and Blood Institute. Title: “Mechanisms of second heart field development regulated by NKX genes.” Role: Co-Investigator (PI: Targoff K) Dates: 01/01/17-12/31/21 Amount: $1,600,000 total Reference: R01HL13143801A1 (PI: Targoff K) 0.5 CM Sponsor: Columbia Data Science Institute, ROADS Provost Ignition grant Title: “Dissecting Spatiotemporal Brain Dynamics” Role: Co-PI (Hillman EMC and Zheng T (Statistics)) Dates: 08/16-08/18 Amount: $100,000 (total) Sponsor: Kavli Foundation pilot project grant Title: “Tracing visual circuits in the fly brain using SCAPE: a novel, fast, whole-brain

imaging technique” Role: Co-PI: (Hillman EMC and Behnia R (Neuroscience)) Dates: 07/01/16-06/30/17 Amount: $50,000 (total) Sponsor: Columbia-Coulter Translational Research Partnership Title: “SCAPE-Tech Pathfinder” Role: PI (Hillman EMC) Dates: 08/16-08/17 Amount: $100,000 (total) Sponsor: Columbia University RISE Program Title “Predicting Volcanic Eruptions Using Real-time 4D+ Microscopy of Bubble Interactions in a Solid-Liquid Mush” Role: Principal Investigator: Lev E and Hillman EMC (co-PIs) Dates: 09/01/2017-08/31/2019 Amount: $200,000 total

Sponsor: Department of Defense (MURI, W911NF-12-1-0594) Title: “Imaging how a neuron computes” Role: Principal Investigator: Yuste R, Key Personnel: Hillman EMC (0.5 mo) with Kenneth

Shepard, Wei Min, Jung-Chi Liao, Dirk Englund, Johnathan Owen, Liam Paninski, Sebasian Seung, Jeff Lichtman and Xiaowei Zhang).

Dates: 10/01/12-9/30/2018 Amount: $3,500,000 (total)

Submitted Funding Requests

Sponsor: National Institute of Neurological Disorders and Stroke. Title “SCAPE microscopy for high-speed 3D imaging of cellular function in behaving animals: Continued innovation, optimization, and dissemination” Role: Principal Investigator: Hillman EMC (1 mo) Dates: 09/01/2018-08/31/2021 Amount: $ 3,931,242 total Reference: 1 U01 NS108213-01 (BRAIN Initiative) Selected for funding, awaiting notice of award


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Completed Funding

Sponsor: National Institutes of Health, National Institute of Neurological Disorders and Stroke. Title: “Imaging the neuronal and metabolic basis of resting state connectivity mapping” Role: Principal Investigator: Hillman EMC (2 mo) Dates: 08/15/11-07/31/17 (NCE) Amount: $1,717,976 ($1,093,750 direct) Reference: 1 R01 NS076628. Awarded on 1st review with 4th percentile score Sponsor: National Science Foundation Title: “CAREER: Interventional Microscopy for In-vivo Investigations of Brain Function” Role: Principal Investigator: Hillman EMC (1 mo) Dates: 03/1/10-02/28/16 Amount: $400,000 ($232,173 direct) Reference: CAREER: 0954796 Awarded on 1st review

Sponsor: NIH, National Institute of Neurological Disorders and Stroke. Title: “Optics and the Brain” (OSA Conference, Hillman and Pavone Chairs). Role: Co-Investigator (PI Quarles G, CEO of OSA) Dates: 04/02/17- 04/05/17 Amount: $10,000 direct Reference: 1R13NS101936-01 Conference grant - Awarded on 1st review

Sponsor: National Institutes of Health, National Institute of Arthritis, Musculoskeletal and Skin Title: “Columbia University Medical Center Skin Diseases Research Center” Role: PI: Bickers DR, Imaging Core co-Director: Hillman EMC (0.6 mo) Dates: 08/01/11 -06/30/17 Amount: $55,000 (direct to imaging core) Reference: P30 AR044535-10 Sponsor: National Science Foundation Title: “IDBR: CMOS cameras for high-frame-rate time-correlated single-photon counting” Role: Principal Investigator: Shepard K, Co-PIs: Hillman EMC (0 mo) and Yuste R Dates: 03/1/10-08/31/16 Amount: $750,000 (total) Reference: IDBR: 1063315 Sponsor: National Institutes of Health, National Eye Institute. Title: “Anticipatory Hemodynamic Signals in Primary Visual Cortex” Role: Co-Investigator (PI: Das A) Dates: 05/01/08-09/29/16 Amount: $1,610,000 ($1,000,000 direct) Reference: 1R01 EY019500

Sponsor: National Science Foundation. Title: “Optics and the Brain Topical Meeting” Role: Principal Investigator: Rogan E, co-PI Hillman EMC Dates: 04/01/15- 05/01/15 Amount: $15,000 direct Reference: 1540895 Conference grant – Awarded on 1st review

Sponsor: National Science Foundation (IGERT) Title: “Optical Techniques for Actuation, Sensing & Imaging of Biological Systems” Role: Principal Investigator: Shepard K, Key Personnel: Hillman EMC (0 mo) Dates: 09/01/08-06/30/15 Amount: $1,200,000 (total) Reference: IGERT 0801530


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Sponsor: National Institutes of Health, National Institute of Biomed Imaging & Bioengineering Title: “Tracking Stem Cells in Engineered Tissues and Organs In Vivo and In Real Time” Role: Principal Investigator: Mao J, Key Personnel: Hillman EMC (0.6 mo) Dates: 09/15/09-04/31/14 Amount: $2,318,400 ($1,440,000 direct) Reference: 1 R01 EB009663-01A2 Sponsor: Columbia Irving Institute Collaborative & Multidisc Pilot Research Award, Phase 2 Title: “Improving imaging biomarkers for brain tumor resection” Role: Principal Investigator: Hillman EMC, co-PIs, McKhann G, Canoll P Dates: 07/01/12-06/30/13 Amount: $75,000 (direct) Sponsor: Kavli Foundation pilot project grant Title: “Fast 3D imaging of neuronal networks in vivo using laser-scanning intersecting

plane tomography (L-SIPT)” Role: PI: Hillman EMC Dates: 12/21/12-12/20/13 Amount: $25,000 Sponsor: Human Frontier Science Program. Title: “In-vivo and In-vitro: cellular and neuro-chemical mechanisms of somatosensory

neurovascular coupling” Role: Principal Investigator: Hillman EMC, co-PI Cauli B (Paris) Dates: 12/01/07-11/31/11 Amount: $750,000 direct Reference: RGY0070/2007-C Awarded on 1st review. 35 funded out of 800 applicants Sponsor: Coulter Foundation (Early Career Award) Title: “Development of depth-resolved optical imaging for melanoma margin mapping and

invasion depth determination” Role: Principal Investigator: Hillman EMC Dates: 09/01/06-08/31/09 Amount: $240,000 ($200,000 direct) Reference: - Awarded on 1st review. Sponsor: National Institutes of Health, National Institute of Neurological Disorders and Stroke. Title: “3D Neurovascular Coupling: A Depth-resolved Voltage Sensitive Dye Imaging

System” Role: Principal Investigator: Hillman EMC Dates: 12/01/05-11/30/08 Amount: $318,000 ($275,000 direct) Reference: 1R21NS053684-01 Awarded on 1st review with 3.9th percentile score Sponsor: NIH, National Institute of Neurological Disorders and Stroke, National Institute of

Biomedical Imaging & Bioengineering, National Cancer Institute. Title: “Advances in optics for biotechnology, medicine and surgery conference XII” Role: Principal Investigator: Hillman EMC, co-PIs: Elson D, Thompson R Dates: 04/01/11- 03/31/12 Amount: $20,000 direct Reference: 1 R13 EB012903-01 Conference grant - Awarded on 1st review


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Sponsor: National Science Foundation. Title: “Advances in optics for biotechnology, medicine and surgery conference XII” Role: Principal Investigator: Hillman EMC, co-PIs: Elson D, Thompson R Dates: 04/01/11- 03/31/12 Amount: $15,000 direct Reference: 1105324 Conference grant - Awarded on 1st review

Sponsor: National Institutes of Health, National Institute of Biomed Imaging & Bioengineering Title: “In-vivo optical molecular imaging with Dynamic Contrast Enhancement (DyCE)” Role: Principal Investigator: Levenson R, Subcontract: Hillman EMC Dates: 07/01/08-06/31/09 Amount: $167,462 Reference: 1 R43 EB008627 Awarded on 1st review Phase I SBIR Industry Collaboration with Cambridge Research & Instrumentation (CRi)

Sponsor: National Science Foundation Title: “Directed Evolution of Specific Cell Penetrating Peptides” Role: Principal Investigator: Banta S, Co-PIs: Morrison B, Hillman EMC (0 mo) Dates: 07/01/09-06/30/12 Amount: $301,677 Reference: 0853946

Sponsor: National Institutes of Health, National Institute of Arthritis, Musculoskeletal and Skin Title: “Pseudo-3D Cytoskeletal Dynamics and Signal Activation in Osteocytes under Flow” Role: Principal Investigator: Guo XE, Key Personnel: Hillman EMC (0.6 mo) Dates: 07/01/10-06/30/12 Amount: $328,943 ($243,000 direct) Reference: 1 R21 AR059917

Sponsor: Defense Advanced Research Projects Agency (DARPA) Title: “Development of a closed-loop brain cooling system” Role: Principal Investigator: Bien F, Consultant: Hillman EMC Dates: 06/15/10 – 12/15/10 Amount: $10,000 (consultant) Reference: SBIR Awarded on 1st review Phase I SBIR Industry Collaboration with Spectral Sciences Inc (SSI)

Sponsor: National Institutes of Health, National Cancer Institute Title: “The Role of Inflammation and Stroma in Digestive Cancer” Role: Principal Investigator: Wang T, Imaging Core co-Director: Hillman EMC (1 mo) Dates: 09/31/06-8/31/11 Amount: $60,000 (direct to imaging core) Reference: 5 U54 CA126513

Sponsor: Columbia Irving Institute Collaborative & Multidisc Pilot Research Award, Phase 1 Title: “Uncovering the Hemodynamic Signature of Glioma with Ultra-fast Multispectral

Optical Imaging” Role: Principal Investigator: Hillman EMC, co-PIs, McKhann G, Canoll P Dates: 11/15/11-03/31/12 Amount: $15,000

Sponsor: Columbia Irving Institute Collaborative & Multidisc Pilot Research Award, Phase 1 Title: “Planning for a Stem Cell Transplantation Rare Genetic Disease Consortium” Role: Principal Investigator: Cairo M, Co-Investigator: Hillman EMC Dates: 11/05/08-02/04/09 Amount: $25,000


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Sponsor: Columbia Faculty Development Research Fellowship Title: “Construction of a custom in-vivo two-photon microscopy system” Role: Principal Investigator: Hillman EMC Dates: 04/01/07-03/31/08 Amount: $25,000 Sponsor: Columbia University SEAS (Rodriguez Family) Title: “Rodriguez Family Junior Faculty Award” Role: Principal Investigator: Hillman EMC Dates: 05/19/08- 05/18/09 Amount: $10,000 Sponsor: National Institutes of Health, National Cancer Institute Title: “3D Imaging of electrical activity in myocardial tissue” Role: Principal Investigator: Pertsov A, Subcontract PI: Hillman EMC Dates: 07/01/06-04/30/08 Amount: $80,000 (subcontract) Reference: 5 R01 HL071635 BRP collaboration with SUNY Syracuse Sponsor: National Institutes of Health, National Institute of Neurological Disorders and Stroke. Title: “Neurovascular coupling in the cerebrum and cerebellum” Role: Principal Investigator: Devor A, Key Personnel: Hillman EMC (4 mo, 5/05-7/06) Dates: 05/01/05-04/30/10 Amount: $2,000,000 Reference: 1 R01 NS05118-01 While at Massachusetts General Hospital Sponsor: National Institutes of Health, National Institute of Biomed Imaging & Bioengineering Title: “Spatiotemporal Brain Imaging: Microscopic and Systems Level” Role: Principal Investigator: Dale A, Key Personnel: Hillman EMC (6-8 mo, 5/05-7/06) Dates: 09/05/02-08/31/07 Amount: $Unknown Reference: 2 R01 EB00790-01A2 While at Massachusetts General Hospital Sponsor: Wellcome Trust (UK) Title: “Wellcome Trust Prize Studentship” Role: Principal Investigator: Hebden J, Awarded to: Hillman EMC (12 mo) Dates: 09/98-01/02 Amount: $80,000 (approx) Reference: 055273 While at University College London


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Invited Lectures

1. Hillman EMC, Special Lecture, ‘Initial clinical testing of the UCL 32 channel time-resolved instrument for optical tomography’, MGH-NMR Center, Department of Radiology, Massachusetts General Hospital, Charlestown, MA (July 2000)

2. Hillman EMC, Special Lecture, ‘Time-resolved optical tomography: development of a 32 channel near-infrared imaging system for cotside monitoring of the neonatal brain’, Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA (Feb 2001)

3. Hillman EMC, Special Lecture,‘Time-resolved optical tomography: development of a 32 channel near-infrared system for neonatal brain imaging’, G.R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, MA (May 2001)

4. Hillman EMC et al, Symposium, ‘Biomedical applications of lasers: time resolved optical tomography’, Rank Prize Fund Mini-symposium on Applications of Free Electron Lasers, Sept 2001, Grasmere, UK (Oral presentation, Invited student)

5. Hillman EMC, Special Lecture, ‘Optical Tomography: from centimeters to microns’, Beckman Laser Institute, University of California, Irvine, CA (June 2003)

6. Hillman EMC, Seminar series: ‘Laminar optical tomography: Non-contact, depth-resolved imaging of rat cortical activation through thinned-skull’, Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA (Aug 2004) (invited)

7. Hillman EMC, Special Lecture, ‘Laminar Optical Tomography: Non-contact, depth-resolved imaging of rat cortical activation through thinned-skull’, Department of Psychology, University of Sheffield, UK (Nov 2004)

8. Hillman EMC, Special Lecture, ‘In-vivo Optical Imaging: from Microns to Centimeters, from Ultraviolet to Near Infra-Red, Department of Biomedical Engineering’, Texas A&M University, TX (Feb 2005)

9. Hillman EMC, ‘Brainmap’ Seminar Series: ‘Spatio-temporal separation of vascular compartments using 3D optical imaging of exposed rat cortex during functional activation’, Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA (Feb 2005) (invited)

10. Hillman EMC, Special Lecture, ‘3D optical imaging of exposed rat cortex during functional activation: Spatio-temporal separation of vascular compartment’, Neurophysics Group, Physics Department, University of California at San Diego (UCSD), CA (April 2005)

11. Hillman EMC, Special Lecture, ‘Invasive and non-invasive functional optical imaging’ Department of Biomedical Engineering, Columbia University, New York, NY (April 2005)

12. Hillman EMC et al, Conference, ‘3D high-resolution optical imaging of cortical activation: Vascular compartment separation using spatio-temporal constraints and priors’ OSA European Conference on Biomedical Optics, June 7-13; Munich Germany. (Oral presentation, contributed, but selected for 30 minute Invited talk)

13. Hillman EMC, Special Lecture, ‘Laminar Optical Tomography: High resolution, depth-resolved functional optical imaging’, Department of Pharmacology, SUNY Upstate University, Syracuse, NY (July 2005)

14. Hillman EMC, Special Lecture, ‘High-resolution 3D imaging of brain function using Laminar Optical Tomography, Two-Photon Microscopy and Functional Magnetic


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Resonance Imaging’, University College London, Department of Medical Physics and Bioengineering, London, UK (March 2006)

15. Hillman EMC, Symposium, ‘Multi-scale in-vivo imaging of functional activation in the somatosensory cortex’, Laboratoire de Neurobiologie, Ecole Superieure de Physique et de Chimie Industrielles, Paris, France (March 2006) (invited)

16. Hillman EMC et al, Conference, ‘High-resolution functional optical imaging: sub-millimeter physiology of living tissue’. OSA Biomedical Topical Meeting, March 19-23; Fort Lauderdale FL. (Oral presentation, contributed, but selected for 30 minute Invited talk)

17. Hillman EMC et al. Conference, ‘High Resolution Functional Optical Imaging of Living Tissues’. IEEE Proceedings of the International Symposium on Biomedical Imaging (ISBI) 2006, April, Arlington VA (Invited)

18. Hillman EMC, Conference, ‘Diffuse Optical Tomography’, In: OSA Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference and Photonic Applications Systems Technologies (CLEO/QELS/PhAST), 2006, June 10; Long Beach CA. (Invited)

19. Hillman EMC, Gordon Conference, ‘High resolution functional optical imaging of exposed cortex in-vivo’, Gordon Research Conference: Lasers in Medicine and Biology, Holderness, NH, July 2006. (Invited)

20. Hillman EMC. Symposium, ‘Functional optical imaging of brain activation: a multi-scale, multi-modality approach’, IEEE/NLM Life Science Systems and Application Workshop, NIH Bethesda, MD, July 2006. (Invited)

21. Hillman EMC et al. Symposium, ‘High resolution functional optical imaging of rodent cortex: investigating mechanisms of functional activation’, at ‘Optical Diagnostic Imaging from Bench to Bedside’ Technical Workshop at the National Institutes of Health 2006, September, NIH Bethesda, MD (Invited).

22. Hillman EMC, Seminar Series, Imaging Neurovascular Coupling in-vivo: from single neurons to BOLD. Mallinckrodt Institute of Radiology, Washington University, St Louis, MI (Feb 2007) (invited)

23. Hillman EMC, Seminar Series: ‘In-vivo optical imaging of hemodynamics and electrical activity’. Department of Electrical Engineering, Columbia University, New York, NY (April 2007) (invited)

24. Hillman EMC, Symposium, ‘Imaging neurovascular coupling in-vivo: from single neurons to BOLD’, at McGovern Institute Symposium: ‘Plumbing the Mind: Brain Activation and the Regulation of Cerebral Blood Flow’ Symposium, MIT Boston, MA (May 2007) (Invited).

25. Hillman EMC, Short Course, ‘Neurovascular Coupling in-vivo: From Single Neurons to BOLD’. Part of the Multi-Modality Brain Imaging Short Course, Massachusetts General Hospital / Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging (June 2007) (invited)

26. *Burgess SA .. Hillman EMC. Conference, ‘High-resolution 3D optical imaging of tissue’, IEEE Proceedings LEOS, Orlando FL, October 2007. (Invited)


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27. Hillman EMC et al. Conference, ‘Multidimensional functional optical imaging of the brain’. OSA Biomedical Topical Meeting 2008. March 16-19; St Petersberg FL. (Invited)

28. Hillman EMC, Seminar Series, In-vivo optical imaging of neurovascular coupling (and a few other things), Department of Biomedical Engineering, Vanderbilt University. Nashville, TN (May 2008) (invited)

29. Hillman EMC, Company Special Lecture, ‘Functional optical imaging’, Cambridge Research and Instrumentation, Woburn MA (May 2008) (invited)

30. Hillman EMC, Gordon Conference, ‘Vascular compartment dynamics during neuronal activation’, Gordon Research Conference on Brain Energy Metabolism and Blood Flow, August 2008, Andover, NH. (Invited)

31. Hillman EMC et al, Conference, ‘Optical Imaging of transmural cardiac propagation’, BMES Annual Meeting, October 2nd 2008, St Louis MO. (Invited)

32. Hillman EMC. Conference, ‘Mouse Organ Imaging’, OSA Frontiers in Optics (FiO) October 19, 2008, Rochester, NY. (invited)

33. Hillman EMC et al. Conference, ‘Multidimensional functional optical imaging of the brain’. OSA Frontiers in Optics (FiO) Oct 19, 2008, Rochester, NY. (Invited ‘Best of the Topicals’ session)

34. *Hillman EMC, Symposium, Photons for functional imaging: Microscopy and optical imaging technologies for in-vivo applications. Proceedings of the Dodd-Walls Center for Quantum Science and Technology Symposium, December 8th, 2008, Queenstown, New Zealand. (Keynote)

35. Hillman EMC, Special Lecture, ‘Photons for functional imaging: Microscopy and optical imaging technologies for in-vivo applications’, Department of Physics, University of Auckland, New Zealand (Dec 2008) (invited)

36. Hillman EMC, Seminar Series, ‘In-vivo optical imaging of neurovascular coupling’, Columbia University MD/PhD Program Research Seminar Series (Dec 2008) (invited)

37. Hillman EMC, Symposium, ‘In-vivo optical imaging of skin’, New York ‘Skin Day’, hosted by the Columbia University Department of Dermatology (Dec 2008) (invited)

38. Hillman EMC, Departmental Seminar, ‘In-vivo optical imaging of neurovascular coupling’, Columbia University Department of Neuroscience (Jan 2009) (invited)

39. Hillman EMC, Seminar Series, ‘Imaging Neurovascular Coupling In-vivo: from Single Neurons to BOLD’, University College London Centre for Neuroimaging Techniques, London, UK (Feb 2009) (invited)

40. Hillman EMC, Seminar Series, ‘In-vivo optical imaging of neurovascular coupling’, Neurolunch Seminar Series, Columbia University Department of Biological Sciences (Feb 2009) (invited)

41. Hillman EMC, Seminar Series, ‘In-vivo optical imaging of neurovascular coupling’, University Paris Descartes, Paris (Feb 2009) (invited)


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42. Hillman EMC, Symposium, ‘Imaging of Proteins in Skin In Vivo’, Symposium on Genetics, Stem Cell Biology and Stem Cell Transplantation in Epidermolysis Bullosa, Columbia Medical Center (Feb 2009) (invited)

43. Hillman EMC, Seminar Series, ‘Exploring the vascular mechanisms of cortical hemodynamics using high-speed in-vivo optical imaging’, Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, New York, NY (Feb 2009) (invited)

44. Hillman EMC, Seminar Series, ‘Photons for functional imaging: Microscopy and optical imaging technologies for in-vivo applications’, Department of Biomedical Engineering, Rutgers University, New Brunswick, NJ (March 2009) (invited)

45. Hillman EMC, Seminar Series, ‘Applications of Laminar Optical in Neuroscience and Dermatology’, Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA (May 2009) (invited)

46. Hillman EMC, Conference, ‘In vivo optical imaging of animal disease models: From micro to macro’. Engineering Conferences International meeting: Advances in Optics for Biotechnology, Medicine and Surgery XI. June 2009, Burlington VT. (Invited)

47. Hillman EMC, ‘In-vivo imaging of liver function, and Hyperspectral microscopy of fresh, healthy and diseased intestine and colon’, Herbert Irvine Cancer Center, Columbia University (Nov 2009) (invited)

48. Hillman EMC, Seminar Series, ‘In-vivo optical imaging of brain and organ function’, Columbia University Children’s Hospital, Department of Pediatrics, New York, NY (Dec 2009) (invited)

49. Hillman EMC, Seminar Series, ‘Laminar Optical Tomography and in-vivo optical imaging. Department of Electrical Engineering’, Ecole Polytechnique Montréal. Montreal, Canada (April 2010) (invited)

50. Hillman EMC, Gordon Conference, ‘Optical neuroimaging’, 2010 Gordon Research Conference on Lasers in Medicine and Biology, July 25–30, Holderness, NH. (Invited)

51. Hillman EMC, Annual meeting, ‘Imaging everything: Harnessing endogenous and exogenous contrast in- vivo’, Society of General Physiologists, New Optical Methods in Cell Physiology, September 2010, MBL Woods Hole, MA. (Invited)

52. Hillman EMC et al, Conference, ‘Opportunities for Biophotonics-based approaches in Drug Discovery & Development’, International Congress on Biophotonics 25-27 Sept 2010, Quebec City, Canada (Invited)

53. Hillman EMC, Seminar Series, ‘Optical imaging and microscopy of the living brain’. Department of Biomedical Engineering, Northwestern University, IL (Sept 2010) (invited)

54. Hillman EMC and *L’Heureux B, Conference, ‘Redox Imaging and metabolism’, International IFR83 annual meeting “Oxidative Metabolism in Health and Diseases”, Sept 27-28, 2010, Paris, France (Invited - Post-doctoral fellow Barbara L’Heureux attended on my behalf) (invited)

55. Hillman EMC, Conference, ‘New Visions for Optical Imaging’. Royal Society Conference: Making light work: Illuminating the future of biomedical optics. Nov 8-9 2010. Kavli Royal Society Centre, Buckinghamshire, UK. (Invited)


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56. Hillman EMC, Symposium, ‘Understanding neurovascular coupling with intravital microscopy and optical imaging’, Neurotechniques Symposium at the Italian Academy for Advanced Studies in America at Columbia University, Dec 3rd 2010. New York (Invited)

57. Hillman EMC, Conference, ‘In-vivo optical imaging and microscopy of neurovascular coupling’. Advanced Imaging Methods Workshop, Jan 19-21 2011, Berkeley CA (Invited)

58. Hillman EMC, Conference, ‘The physiological limits of spatial and temporal resolution in fMRI’, Ultra High Field Workshop sponsored by the International Society of Magnetic Resonance in Medicine (ISMRM), Feb. 20-23, 2011, Lake Louise, Canada. (Invited)

59. Hillman EMC, Seminar Series, ‘Imaging everything, harnessing endogenous and exogenous contrast for in-vivo imaging’, Department of Physiology Imaging Core, McGill University, Montreal Canada (March 2011) (invited)

60. Hillman EMC, Site visit, ‘In-vivo optical imaging of the neurovascular network’, Kavli Institute at Columbia University, Site Visit Seminar to Board. Columbia University, NY (March 2011) (invited)

61. Hillman EMC, Grand Rounds, ‘Understanding neurovascular coupling with intravital microscopy and optical imaging’, Department of Neurosurgery, Columbia University, NY (March 2011) (invited)

62. Hillman EMC, Seminar Series, ‘In-vivo optical imaging; from animal to man’, Irving Institute for Translational Medicine Seminar. Columbia University, NY (March 2011) (invited)

63. Hillman EMC, Conference, ‘Imaging the Neurovascular Unit’, Teaching session on Neurovascular Unit at Brain 2011, May 24-28, Barcelona, Spain (Invited)

64. Hillman EMC, Think tank and speaker, ‘(Brain) Imaging’. Kavli, Allen, Gatsby meeting on Nano-Neuro, Sept 10-13, 2011, Royal Society Kavli Center, UK, (Invited) – this is the meeting at which the BRAIN initiative was founded.

65. Hillman EMC, Conference, ‘Phantoms for quantitative multimodal imaging’, at ‘Standards for Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices’ NIST Conference, Catholic University of America, Nov 7-8th 2011, Washington DC. (Invited)

66. Hillman EMC, Symposium, ‘Hyperspectral and Dynamic In-vivo Molecular Imaging and Microscopy’, at ‘Imaging the Essence; From Medical Diagnosis to Art Restoration’ Symposium, Center for Molecular and Biomolecular Imaging, Duke University, (Dec 2011) (Invited)

67. Hillman EMC, *Grosberg LE et al, Conference, ‘Multi-plane two photon microscopy for high speed 3D neuroimaging’ Paper 8207G-162, SPIE Photonics West, 23 January 2012, San Francisco CA. (Invited) *Featured in Nature Photonics News and Views of as a conference highlight.

68. Hillman EMC, Conference, ‘Hot-Topics: In-vivo Microscopy: a New Window on the Brain’, SPIE Photonics West, 23 January 2012, San Francisco CA (Invited Plenary)

69. Hillman EMC, *Kozberg MG et al, Conference, ‘Novel in vivo imaging techniques for studying the neurovascular unit Imaging and novel diagnostics’, 7th International Symposium on Neuroprotection and Neurorepair Potsdam Neurotrama and Repair, 2nd - 5th of May 2012, Potsdam, Germany (Invited - MD/PhD student Mariel Kozberg presented in my place).


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70. Hillman EMC, Seminar, ‘Neurophotonics: Optical imaging and in-vivo microscopy to understand the living brain’, Brown University, Biomedical Engineering Group (Sept 2012). (invited)

71. Hillman EMC, Seminar Series, ‘Functional Optical Imaging’, Stonybrook University, Department of Biomedical Engineering (Sept 2012). (invited)

72. Hillman EMC, Special Event, ‘Reading the Brain: What can we measure?’, Inauguration of the Grossman Center for the Statistics of the Mind, Columbia University, (Oct 2012) (invited)

73. Hillman EMC, Course, ‘In-vivo optical imaging and microscopy of neurovascular coupling’, at Photonic Imaging in Neuroscience Workshop, Marseille, France, 1-3rd Oct 2012 (Invited)

74. Hillman EMC, Conference, ‘Optical Imaging and Microscopy of the Living Brain’ at OSA Frontiers in Optics, Rochester NY, 14-18 Oct 2012 (Invited)

75. Hillman EMC, Seminar Series, ‘In-vivo dynamic and hyperspectral microscopy’, Rice University, Department of Biomedical Engineering. (Nov 2012). (invited)

76. Hillman EMC, Conference, ‘Optical Neuroimaging’, at OSA ‘Optics in the Life Sciences’ congress, Hawaii, 14-18 April 2013 (Plenary)

77. Hillman EMC, Seminar Series, ‘Imaging with Light (Biophotonics in Brief)’, Columbia University Medical Physics Seminar series. April 2013 (invited)

78. Hillman EMC, Conference, ‘In-vivo dynamic and hyperspectral microscopy’, American Association of Anatomists ‘Experimental Biology 2013’ Meeting, Boston MA, 20-24th April 2013 (Invited)

79. Hillman EMC, Company summit, ‘Small Animal Imaging with Dynamic Contrast (DyCE)’, PerkinElmer Revolutionaries for Global Health Summit (RGHS), 8-9th May 2013 (Invited as inventor of licensed technology)

80. Hillman EMC, Conference, ‘Cellular, vascular and functional development of the brain', ‘Highlights from the Journal of Cerebral Blood Flow and Metabolism’ special session at Brain 2013, 20-23rd May 2013, Shanghai, China. (Invited)

81. Hillman EMC, Conference, ‘Exposed-cortex optical mapping of brain function: From animal to man’, Society for Brain Mapping and Therapeutics, 12-14th May 2013, Baltimore MD (Invited)

82. Hillman EMC, Symposium, ‘Exploring the neurovascular basis of functional neuro-imaging’, Imaging Sciences Pathway (ISP) retreat, Washington University, St Louis MO. (June 2013). (Symposium Keynote),

83. Hillman EMC, Workshop, ‘Functional imaging contrast in infants and children’, Small Workshop on Building Bridges to Facilitate Understanding and Treating ASD, Sackler Foundation, 18-19th October 2013, New York NY. (Invited).

84. Hillman EMC, Conference, ‘In-vivo dynamic and hyperspectral microscopy’, 7th Annual Workshop on Advanced TCSPC Techniques, 21-22 October 2013, Bethesda MD, (Invited).

85. Hillman EMC, Think tank, ‘Depth and Speed: What are the Limits?’, OSA Spatially Precise Optogenetics at Depth Incubator Meeting, 8-10th December 2013 in Washington, DC. (Invited)


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86. Hillman EMC, Conference, ‘Intraoperative imaging of the human brain and fast 3D whole-field in-vivo microscopy’, 11th Advanced Imaging Methods Workshop, UC Berkeley, 29-31st January 2014, (Invited)

87. Hillman EMC, Conference, ‘Hyperspectral and Dynamic contrast: What your eyes can’t see’, NextMed, Medicine meets Virtual Reality (MMVR21) meeting, 19-22nd February 2014, Manhattan Beach CA. (Plenary)

88. Hillman EMC, Conference, ‘Brain Blood Flow and Metabolism; Neurovascular Mechanisms and Postnatal Brain Development’, ISOTT (International Society on Oxygen Transport to Tissue), June 28th, 2014, London (Keynote)

89. Hillman EMC, Course, ‘Methods for ultra-fast 3D volumetric microscopy in-vivo’ at the ‘Montreal Light Microscopy Course, 14-18th July 2014 (Plenary)

90. Hillman EMC. Conference, ‘Multi-scale optical imaging and photo-manipulation of the living brain’, ‘Imaging in 2020, Imaging the Immune System: Look into the long term future of Imaging’, September 21 – 25, 2014, Jackson Hole WY (Invited)

91. Hillman EMC, Grand Rounds (Neurology), “Neurovascular coupling - why is it important?” Columbia University Medical Center. (Oct 2014)

92. Hillman EMC, Live Webinar, “Multiscale optical imaging and microscopy of neurovascular coupling in the living brain”, sponsored by Elsevier and Andor (Jan 2015)

93. Hillman EMC, Conference, ‘Dynamic in-vivo optical imaging and microscopy of the living brain’, SPIE Photonics West, San Francisco CA, Feb 2015. (Invited)

94. Hillman EMC, Conference Symposium, ‘Optics in Neuroscience’, Special OSA-sponsored symposium to celebrate ‘The International Year of Light; at the AAAS annual meeting, San Jose CA, Feb 2015. (Invited)

95. Hillman EMC, Conference, ‘Methods for ultra-fast 3D volumetric microscopy in-vivo’, Association of Biomolecular Resource Facilities (ABRF) meeting, St Louis (March 2015) (Invited)

96. Hillman EMC, Symposium, “The role of the vascular endothelium in functional neurovascular coupling” Gladstone Institute Symposium on Neurovascular Imaging, San Francisco CA, (March 2015)

97. Hillman EMC, Invited Seminar, ‘New approaches to fast 3D microscopy in awake, behaving organisms’, Stanford University (Deisseroth and Schnitzer labs). (March 2015)

98. Hillman EMC, Symposium, “Multi-scale imaging from single cells to patients”, Columbia National Academy of Engineering Regional Meeting, (April 2015)

99. Hillman EMC, Conference, ‘'Swept confocally-aligned planar excitation' (SCAPE) microscopy for high speed volumetric imaging in behaving animals’, OSA Optics in the Life Sciences Congress (Optical Molecular Probes, Imaging and Drug Delivery), Vancouver (April 2015) (Invited)

100. Hillman EMC, Course, “Swept, Confocally-Aligned Planar Excitation (SCAPE) microscopy for fast in-vivo volumetric imaging”, Cold Spring Harbor Course speaker “Quantitative Imaging: From Cells to Molecules”, Cold Spring Harbor (April 2015) (Invited

final lecture)


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101. Hillman EMC, Symposium, “The role of endothelial propagation in neurovascular coupling”, University Paris-Descartes Symposium: The Brain, beyond neurons. Paris, France (May 2015)

102. Hillman EMC, Seminar Series, “The role of neurovascular coupling in brain development, disease and interpretation of the fMRI BOLD signal”, Weill Cornell Medical College Progress in Neuroscience (PINS) seminar series, (June 2015)

103. Hillman EMC, Invited Seminar, “In-vivo brain imaging: Building microscopes and using them”, Duke University Departments of Biomedical Engineering and Neuroscience, (June 2015)

104.

105. Hillman EMC, Course, “Light-sheet microscopy, and whole-brain imaging”, 2015 Cold Spring Harbor Lab course on Imaging Structure & Function in the Nervous System (Aug 2015) (Expert lecturer)

106. Hillman EMC, Conference, “Swept Confocally-Aligned Planar Excitation (SCAPE) Microscopy for High Speed Volumetric Imaging in Behaving Animals”, Microscopy and Microanalysis meeting (M&M2015), Portland, Oregon, (August 2015) (Keynote)

107. Hillman EMC, Special Lecture, “Multi‐scale in‐vivo optical imaging and microscopy”, Multiscale imaging initiative at the Morgridge Institute, UW-Madison (Aug 2015) (invited)

108. Hillman EMC, Course, “Swept, Confocally-Aligned Planar Excitation (SCAPE) microscopy for fast in-vivo volumetric imaging”, Optical Microscopy and Imaging in the Biomedical Sciences (OMIBS) course at MBL, Wood's Hole, MA (Sept 2015) (Horizon’s

Lecture)

109. Hillman EMC, ‘Optical Techniques in Brain Research – Human Neuroimaging, OSA Label-Free Optical Techniques for Biomedical Diagnostics & Imaging Incubator meeting, 16-18 September 2015 in Washington DC (Invited, declined)

110. Hillman EMC, Conference, “High speed 3D imaging of living organisms using SCAPE microscopy”, IEEE Photonics Conference, (Oct 2015) (Invited)

111. Hillman EMC, Conference, ‘TBD’, Janelia Farm conference: ‘Emerging Tools for Acquisition and Interpretation of Whole-Brain Functional Data', (Nov 2015) (Invited, declined

due to overlap with Brain Prize meeting)

112. Hillman EMC, Special Symposium, ‘SCAPE microscopy for high-speed 3D imaging of the living brain’, The Brain Prize meeting (Commemorating the 2015 Brain Prize to Denk, Tank, Svoboda & Konnerth for in-vivo two-photon microscopy), Copenhagen, Denmark (Nov 2015) (Special Final Lecture)

113. Hillman EMC, Symposium, “High speed optical imaging of the awake, behaving brain’”, MIT Neurotechnology Symposium , MIT Center for Neurobiological Engineering, (Nov 2015). (Invited)

114. Hillman EMC, Special seminar, “SCAPE microscopy for high-speed 3D imaging of the living brain”, Harvard Department of Cell Biology, (Nov 2015)

115. Hillman EMC, Departmental Seminar Series, ‘The role of neurovascular coupling in brain development, disease and interpretation of the fMRI BOLD signal’ Department of Neuroscience, Medical University of South Carolina (Nov 2015)


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116. Hillman EMC et al, “SCAPE microscopy for high-speed in-vivo volumetric microscopy in behaving organisms”, NIH BRAIN Initiative Investigators Meeting, Bethesda MD, (Dec 2015) (Invited speaker, one of 32 selected from 125 BRAIN grant awardees)

117. Hillman EMC, Departmental Seminar Series, “Building and using in-vivo microscopes to understand brain function and physiology”, Pioneers in Biomedical Research Seminar, Virginia Tech, (Dec 2015)

118. Hillman EMC, Grand Rounds,” In-vivo optical imaging of neurovascular coupling and cellular function”, Department of Ophthalmology, Columbia University Medical Center, (Jan 2016)

119. Hillman EMC, Colloquium, “Multi-scale optical imaging for capturing dynamic brain function in-vivo”, Department of Physics and Astronomy, Columbia University, (Jan 2016)

120. Hillman EMC, Guest speaker, “Imaging the developmental trajectory of neurovascular coupling”, Columbia University Research Consortium on Autism Spectrum and Related Neurodevelopmental Disorders, (Jan 2016)

121. Hillman EMC, Conference, ‘The role of vascular endothelium on neurovascular coupling and the BOLD signal’, UK Royal Society Theo Murphy Meeting - Interpreting BOLD: A dialogue between cognitive and cellular neuroscience, (Jan 2016) (Invited)

122. Hillman EMC, Conference, “High-speed light sheet imaging of in-vivo brain function with SCAPE microscopy”, AIM 13th Annual Advanced Imaging Methods (AIM) Workshop, Berkley, CA (Feb 2016) (Invited)

123. Hillman EMC, Conference, “High-speed light sheet imaging of in-vivo brain function with SCAPE microscopy”, SPIE Photonics West, part of ‘High-Speed Biomedical Imaging and Spectroscopy: Toward Big Data Instrumentation and Management’ symposium, San Francisco, Feb 2016 (Invited)

124. Hillman EMC, Departmental Seminar Series, “High-speed 3D microscopy of in-vivo brain function and physiology”, Department of Anatomy and Neurobiology at Washington University School of Medicine, (February 2016)

125. Hillman EMC, Seminar Series, “Novel approaches to high-speed 3D microscopy of in-vivo brain function and physiology”, Champalimaud Foundation, Portugal (March 2016)

126. Hillman EMC, Workshop, “1.5 Tb per hour: What to do with high-speed 3D microscopy images of the living brain”, Columbia Data Sciences Institute Workshop on Data Visualization (March 2016)

127. Hillman EMC, Course, Cold Spring Harbor “Quantitative Imaging: From Cells to Molecules”, Cold Spring Harbor (April 2016) (Invited Course Instructor)

128. Hillman EMC, Conference, “Multiscale optical imaging of the living brain”, Special speaker for the Journal of Histochemistry & Cytochemistry session on Neuro-Imaging and Neuro-Oncology, Experimental Biology, San Diego (April 2016) (Special guest invited speaker)

129. Hillman EMC, Symposium, ‘SCAPE microscopy for high-speed 3D imaging of the behaving brain’, Brain Conference: The Brain in focus: New approaches to imaging neurons and neural circuits – Denmark, April 17 - 20, 2016 (Invited)


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130. Hillman EMC, Departmental Seminar Series, “High-speed imaging and 3D microscopy of in-vivo brain function and physiology”, Department of Biomedical Engineering, Northwestern University, (May 2016)

131. Hillman EMC, Symposium, ‘1.5 Tb per hour and 5 dimensions: Fun with high-speed volumetric imaging of the behaving brain’, 3rd Annual Meeting on Quantifying structure in large neural datasets, Grossman Center for the Statistics of the Mind, Columbia University, May 26-27, 2016 (Invited)

132. Hillman EMC, Symposium, ‘SCAPE microscopy for high-speed 3D imaging of the behaving brain’, Neurizons 2016, Gottingen, Germany, May 31st-June 3rd 2016 (Invited)

133. Hillman EMC, Conference, “TBD”, Israel Society for Microscopy Golden Jubilee meeting, Haifa, Israel May 31st-June 3rd 2016. (Invited) (declined due to overlap with another meeting),

134. Hillman EMC, Course,‘Light-sheet microscopy’ and ‘SCAPE microscopy for high-speed 3D imaging of the awake, behaving brain’, Neurophotonics Course, Laval University, Quebec, June 2016, (Invited course instructor)

135. Hillman EMC, Gordon Conference, “Imaging in-vivo functional dynamics at high spatiotemporal resolution”, Gordon conference on Bioanalytical Sensors, Rhode Island, June 2016 (invited)

136. Hillman EMC, Symposium, “Towards novel, multiscale imaging methods for guiding brain tumor resection”, Department of Neuro-oncology, Columbia University (July 2016)

137. Hillman EMC, Gordon Conference, “SCAPE Microscopy for high-speed 3D imaging of living things”, Gordon conference on Lasers in Medicine and Biology, July 2016 (invited)

138. Hillman EMC, Course, “SCAPE microscopy for high-speed 3D imaging of the awake, behaving brain”, 2016 Cold Spring Harbor Lab course on Imaging Structure & Function in the Nervous System (Aug 2016) (Expert lecturer and SCAPE demo system)

139. Hillman EMC, Course, “SCAPE microscopy for high-speed light sheet imaging”, EMBO light sheet microscopy course, Dresden, Germany (August 2016) (Invited)

140. Hillman EMC, Conference, “High-speed, in-vivo 3D imaging with SCAPE microscopy”, 3rd International Light Sheet Microscopy Meeting in Sheffield, UK, Aug 31st - Sept 3rd 2016 (Invited)

141. Hillman EMC, Course, BIGSS '16: Biophotonics and Imaging Graduate Summer School September 5-9 2016 , Galway, Ireland. (Invited course instructor) – declined

142. Hillman EMC, Symposium, “Microscopy and Bioengineering”, Symposium for the inauguration of the Technical University of Munich interdisciplinary center for translational cancer research (TranslaTUM), Munich, Germany, 15th Sept 2016 (Keynote)

143. Hillman EMC, Special Seminar, “Multi-scale imaging of brain function”, University of Zurich, Switzerland, (Sept 2016)

144. Hillman EMC, Conference, “Visualizing the neural basis of resting state hemodynamics”, at the 5th Biennial Resting-State Brain Connectivity Conference, Vienna, Austria, 19th September 2016 (Invited)


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145. Hillman EMC, Symposium, ‘Capturing high-speed activity in awake, behaving brain’, 17th Annual UNC Neuroscience Symposium, University of North Carolina at Chapel Hill, Oct 19th 2016. (symposium speaker)

146. Hillman EMC, Departmental Seminar Series, “SCAPE microscopy for high-speed 3D imaging of living things”, Department of Biomedical Engineering, Rice University, (October 2016).

147. Hillman EMC, Departmental Seminar Series, “SCAPE microscopy for high-speed 3D imaging of living things”, Department of Biomedical Engineering, Tufts University (November 2016).

148. Hillman EMC et al, “SCAPE microscopy for high-speed 3D imaging of Fantastic Beasts”, NIH BRAIN Initiative Investigators Meeting, Bethesda MD, (Dec 2016) (Invited Highlight

speaker)

149. Hillman EMC (Galwaduge P. T.), Conference, ‘Single objective light sheet microscopy’, Adaptive Optics and Wavefront Control for Biological Systems III meeting at SPIE Photonics West, San Francisco CA, Jan 28th - Feb 2nd 2017 (Invited – to be given by grad student owing to planned lab move)

150. Hillman EMC, Conference, ‘SCAPE microscopy for high-speed 3D imaging of fantastic beasts’, Light Microscopy Australia, 1-3rd February 2017 (Plenary)

151. Hillman EMC, Panel, ‘BRAIN Initiative Innovation Panel’, AAAS symposium organized by the Allen Institute, Boston MA, 17-20th February 2017. (Invited Panel Speaker)

152. Hillman EMC, Gordon Conference, ‘The role of the vascular endothelium in neurovascular coupling – a unifying model?’, Glial Biology: Functional Interactions and Glia & Neurons Gordon Research Conference, Ventura CA, March 5-10th 2017. (invited)

153. Hillman EMC, Conference, ‘A second-generation SCAPE microscopy system for high-speed 3D imaging of living things’, OSA Bio-Optics: Design and Application, Optics in the Life Sciences Congress, San Diego, April 2017. (Invited)

154. Hillman EMC. Symposium, ‘SCAPE microscopy for high-speed 3D imaging of the awake, behaving brain’, Harvard Medical School's Neuroscience Symposium, May 2017 (invited)

155. Hillman EMC, Think Tank, ‘New high resolution imaging modalities for the CNS’, Twenty-fourth Annual Glaucoma Foundation Optic Nerve Rescue and Restoration Think Tank, New York, June 9-10, 2017 (invited).

156. Hillman EMC, Symposium, ‘TBD’, Sculpted Light in the Brain Conference, UC Berkeley, June 9th 2017. (Invited, declined due to meeting overlap)

157. Hillman EMC, Seminar Series, ‘Visualizing the neural underpinnings of resting state fMRI’, National Institute on Drug Abuse (NIDA), Intramural Research Program (IRP) Seminar Series, June 13, 2017 (Invited)

158. Hillman EMC, Workshop, ‘High-speed optical imaging and microscopy’, Chan Zuckerberg Science workshop on Meso and macro scale imaging, San Francisco, 20-21 June 2017 (invited).

159. Hillman EMC, Course, “SCAPE microscopy for high-speed 3D imaging of the awake, behaving brain”, 2017 Cold Spring Harbor Lab course on Imaging Structure & Function in the Nervous System (Aug 2017) (Expert lecturer)


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160. Hillman EMC, Conference, ‘Seeing is Believing – Pushing the limits of high speed in-vivo microscopy’, The Scientist Magazine Expo, Chicago, Sept 11–13, 2017. (Invited)

161. Hillman EMC, Annual Meeting, ‘New developments in SCAPE microscopy for high-speed 3D neuroimaging’, Society for General Physiologists Annual Meeting, theme: “The Optical Revolution in Physiology: From Membrane to Brain”, Woods Hole, Sept. 6-10, 2017 (Invited)

162. Hillman EMC, Annual Meeting, ‘Fast 3D microscopy of the entire awake behaving fly brain using SCAPE microscopy’, Simons Foundation Collaboration on Global Brain Annual Meeting, Sept. 10-12, 2017 (Invited)

163. Hillman EMC, Dinner Speaker, ‘New methods for high-speed neurovascular imaging’, Ophthalmic Laser Surgical Society Meeting Dinner, Guest Speaker, New York, Sept 21st 2018. (invited)

164. Hillman EMC, Symposium, ‘TBD’, 11th Biennial Minnesota Workshop of the Center for Magnetic Resonance Research, “Cells to Networks”. University of Minnesota, MN, Oct 5 - 7, 2017 (invited, declined).

165. Hillman EMC, Symposium, ‘High-speed, brain-wide imaging of neural activity with SCAPE and WFOM’, 5th International Symposium on Frontiers in Neurophotonics, Bordeaux, France, Oct 2017, (Invited)

166. Hillman EMC, Symposium, ‘High-speed imaging of whole-brain activity’, Optogenetic Research Society Japan, Sendai, Japan, Oct 21 - 22, 2017 (invited).

167. Hillman EMC, Invited Seminar, “High-speed imaging of whole-brain activity”, University of Electro-Communications (UEC), Tokyo, Japan, (October 2017).

168. Hillman EMC, Symposium, ‘SCAPE microscopy for whole-brain functional imaging’, ‘Emerging Tools for Acquisition and Interpretation of Whole-Brain Functional Data', Janelia Farm HHMI Campus, Ashburn VA, 5-8 Nov 2017, (Invited)

169. Hillman EMC, Symposium, ‘SCAPE Microscopy for High-speed 3D Imaging of Living Things’, NIH Frontiers in Light Microscopy Symposium, NIH Campus, Bethesda, 17 Nov 2017 (Invited)

170. Hillman EMC, Symposium, ‘Real-time imaging of whole-brain activity’, 21st Annual Photonics Center Symposium on the topic of Neurophotonics, Boston University, Boston MA, Nov 30, 2017 (invited).

171. Hillman EMC, Symposium, ‘Real-time imaging of whole-brain activity’, Max Planck Florida Institute for Neuroscience, Jan, 2018 (invited)

172. Hillman EMC, Plenary, ‘High-speed optical imaging of brain-wide activity’, SPIE Photonics West, Neurophotonics Plenary Hot Topics, San Francisco CA, Jan 28, 2018 (invited)

173. Hillman EMC, Conference, ‘SCAPE microscopy for high-speed 3D imaging of living tissues’, SPIE Photonics West BiOS, San Francisco CA, Jan 27-Feb 1, 2018 (invited)

174. Hillman EMC, Invited Seminar, ‘High-speed imaging of whole-brain activity’, MIT Modern Optics Seminar Series, Boston MA, Feb 2018. (invited)

175. Hillman EMC, Conference, ‘High-speed imaging of whole-brain activity’, OSA Optics and the Brain, Fort Lauderdale FL, April 2018 (invited)


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176. Hillman EMC, Seminar Series, ‘High-speed imaging of whole-brain activity’, Department of Bioengineering, Lehigh University, March 2018. (invited)

177. Hillman EMC, Symposium,‘Prismatic light-sheet microscope’, Hey, What’s the Big Idea? Cell Center Conference (Erik Jorgensen), Department of Biology, University of Utah, May 2018 (invited).

178. Hillman EMC, Symposium, ‘SCAPE microscopy for high-speed volumetric imaging of neural activity’, NSF Neural Imaging Symposium, University of Utah, May 2018 (invited).

179. Hillman EMC, Course Invited Instructor, ‘Light Sheet Microscopy / SCAPE demo’, Analytical and Quantitative Light Microscopy course at MBL Woods Hole, May 2018. (invited)

180. Hillman EMC, Workshop, ‘TBD’, Janelia Workshop on 3D Holography and Volumetric Imaging in Neural Circuits, HHMI Janelia Farm, May 2018 (invited)

181. Hillman EMC, Symposium, ‘TBD’, Dodd-Walls Symposium, University of Aukland, June 2018 (invited, declined)

182. Hillman EMC, Technical Workshop, ‘High-speed in-vivo mapping of neural activity in awake, behaving animals’, Investigating neural substrates of perception and cognition with large-scale data, Federation of European Neuroscience Societies (FENS) Forum 2018, Berlin, Germany, July 7-11 2018 (invited).

183. Hillman EMC, Gordon Conference ‘Crossing Temporal Scales: Imaging the Neural Correlates of Brain Hemodynamics’, In Vivo Magnetic Resonance Gordon Research Conference, Andover NH, July 2018 (invited)

184. Hillman EMC, Minisymposium, ‘Next-generation SCAPE microscopes for high-speed neuroimaging’, Engineering in Medicine and Biology Conference, Hawaii, July 2018 (invited)

185. Hillman EMC, Course, ‘SCAPE Microscopy’ (Lectures and demo system), EMBO practical course on light sheet microscopy, Dresden, Germany, August 2018 (invited)

186. Hillman EMC, Conference, ‘SCAPE Microscopy’, 10th Anniversary Light sheet fluorescence microscopy conference (LSFM2018), Dresden, Germany, August 2018 (invited)

187. Hillman EMC, Course, ‘High-speed optical imaging and microscopy of in-vivo brain function’, BIGSS '18: Biophotonics and Imaging Graduate Summer School, Galway, Ireland. Aug 28-Sept 1 2018, (invited)

188. Hillman EMC, Conference, ‘High-speed optical imaging and microscopy of in-vivo brain function’, Photonics Ireland, Galway, Ireland. Sept 2018, (invited)

189. Hillman EMC, Seminar Series, ‘High-speed imaging of whole-brain activity’, Stanford Neurosciences Institute, Stanford University, 27th Sept 2018 (invited).

190. Hillman EMC, Seminar Series, ‘TBD’, In-vivo Cellular Molecular Imaging Center seminar series, Johns Hopkins University, 17th Oct 2018 (invited).

191. Hillman EMC, Symposium, ‘TBD’, Picower Fall Symposium, Picower Institute for Learning and Memory, MIT, 23rd Oct 2018 (invited).

192. Hillman EMC, Conference: short-course, ‘High-speed volumetric microscopy and wide-field optical mapping of whole-brain activity’, “Functional, structural, and molecular imaging, and big data analysis”, Society for Neuroscience annual meeting, San Diego, Nov 2018. (invited).


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193. Hillman EMC, Conference: mini-symposium, ‘TBD’, “The Dynamic Brain: signatures of fast functional reconfiguration, their interpretability and clinical value”, Society for Neuroscience annual meeting, San Diego, Nov 2018. (invited).

194. Hillman EMC, Seminar Series, ‘TBD’, Department of Neuroscience, Baylor College of Medicine, Houston TX, Nov 2018 (invited).

195. Hillman EMC, Symposium, ‘TBD’, Austin Conference on Learning and Memory, Austin TX, April 2019 (invited).

196. Hillman EMC, Symposium, ‘TBD’, Imaging Voltage: a Next Generation Technology for Neuroscience Symposium, Columbia University, 13-14th Dec 2018. (invited).

197. Hillman EMC, Grand Rounds, ‘TBD’, UCLA Department of Neurology. 9th Jan 2019 (invited).

198. Hillman EMC, Seminar Series, ‘TBD’, Georgia tech / Emory Neural Engineering Center seminar, 14th Jan 2019. (invited).

199. Hillman EMC, Conference: ‘TBD’, Biological Fluorescence Subgroup Symposium, Biophysical Society Meeting, Baltimore MD, 2-6th March 2019. (invited).

200. Hillman EMC, Conference: ‘TBD’, Cold Spring Harbor Meeting on the Blood-Brain Barrier, ‘Imaging and function of the blood-brain barrier in health and disease’ session, April 3 - 6, 2019. (invited).

201. Hillman EMC, Seminar Series, ‘TBD’, Biophysics Seminar Series, Princeton University, Spring 2019 (invited).

202. Hillman EMC, Conference, ‘TBD’, Sculpted Light in the Brain, Royal Society London, June 20-21 2019 (invited).

Pending Departmental / Seminar Invitations: Neuroscience Program & Dept. of Cellular and Molecular Medicine at the University of Ottawa Institute of Mediterranean Neurobiology, Aix-Marseille University, France Department of Biomedical Engineering, Vanderbilt University Department of Bioengineering, Northeastern University Department of Biomedical Engineering, Lehigh University Biophotonics & Bioimaging Seminar Series, UC Davis Department of Biomedical Engineering, City College NY Mount Sinai Microscopy Seminar Series Department of Physiology and Biophysics. Dalhousie University, Halifax, Nova Scotia Department of Biomedical Engineering, Carnegie Mellon University Department of Biomedical Engineering, Texas A&M University Beckman Laser Institute, UC Irvine Participation in Discussion Panels and Workshops

1) NIBIB Discussion Panel member: “Accelerating Clinical Translation of Biomedical Imaging” at the IEEE International Symposium on Biomedical Imaging, Washington DC, April 2006


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2) Discussion Panel Organizer and Moderator: “Optics in Neuroscience” at the Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside, National Institutes of Health, Bethesda MD, Sept 2006

3) Discussion Panel Member: “Optical Cancer Imaging” at the Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside, National Institutes of Health, Bethesda MD, Sept 2006

4) Discussion Panel Organizer and Moderator: “Clinical Molecular Imaging” at OSA Biomed Topical Meeting, St Petersberg FL, March 2008

5) Discussion Panel Member: “Cost effectiveness” at the Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside, National Institutes of Health, Bethesda MD, Sept 2009

6) Discussion Panel Member, “Global Immersion snapshot panel” at the NCIIA / BMEIdea Alliance Meeting, BMES, Hartford CT, Oct 2011

7) Discussion Panel Member, “University Forum on Interdisciplinary Neuroscience”, Columbia Event to announce $200 M gift from Mortimer B. Zuckerman. Panel with Richard Axel, Eric Kandel, Geraldine Downey, Kenneth Forde and David Strauss, Chaired by Tom Jessell. December 2012.

8) Discussion Panel Leader, “New Methodologies”, Columbia Zuckerman Mind Brain Behavior Institute cross-department retreat, New York Academy of Sciences, January 2013.

9) Invited participant: ‘The Human Placenta Project Workshop’, NIH (National Institute for Child Health and Development), Potomac, MD, May 27-28, 2014.

10) Invited participant: NIH Director’s Opioid Meeting “Development of Safe, Effective, Non-Addictive Pain Treatments”, NIH Campus, Bethesda MD, June 16th, 2017.

11) Panel member for AAAS News Briefing “Leading-Edge BRAIN Imaging Tools: Applications and Results, AAAS meeting, Boston MA, 17th Feb 2017.

12) BIO International Convention BRAIN initiative panel on “Mapping the Brain at the ‘Speed of Thought’, Boston MA, 7th June 2018.

13) Panel member, BRAIN PI Meeting: “Commercialization of Research Tools Panel”, Bethesda MD, 11th April 2018.


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Conference abstracts and other presentations

(presentation type is noted when presenter is Hillman or a Hillman trainee)

CA1) Hebden JC, Schmidt FEW, Fry ME, Hillman EMC, Schweiger M, Delpy DT, Imaging of tissue-equivalent phantoms using the UCL multi-channel time-resolved instrument, In: OSA European Conference on Biomedical Optics (ECBO), OSA Technical Digest, Optical Society of America, Washington DC; 2000, 1999, June 14; Munich, Germany.

CA2) Hillman EMC, Hebden JC, Schmidt, FEW, Arridge SR , Fry ME, Schweiger M, Delpy DT. Initial clinical testing of the UCL 32 channel time-resolved instrument for optical tomography. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC; 2000, April 2-5; Miami FL. (Oral presentation, contributed)

CA3) Hillman EMC et al, The MONSTIR 32 channel near-infrared time-resolved optical tomography system for medical imaging, Rank Prize Fund Mini-symposium on Applications of Fast Low-level Light Detection, Sept 2000, Grasmere, UK (Oral presentation, Invited student: won outstanding short paper award)

CA4) Hebden JC, Schmidt, FEW, Hillman EMC, Arridge SR, Schweiger M, Delpy DT. Optical tomography of the human forearm. In: Gandjbakhche AH, editor, Proceedings of the Inter-Institute Workshop on In Vivo Optical Imaging at the NIH, OSA, Washington DC, 2000; Sept 16-17 1999; Bethesda MD.

CA5) Dehghani H, Hillman EMC, Schweiger M, Arridge SR, Delpy DT. Optical tomography of a 3D multilayered head model. In: Chance B, Alfano RR, Tromberg BJ, Tamura M, Sevick-Muraca EM, editors. Proc SPIE 4250, p. 45-52, Optical Tomography and Spectroscopy of Tissue IV; 2001 Jan 19-25; San Jose, CA.

CA6) Hillman EMC, Dehghani, H, Hebden JC, Arridge SR, Schweiger M, Delpy DT. Differential imaging in heterogeneous media: limitations of linearization assumptions. In: Chance B, Alfano RR, Tromberg BJ, Tamura M, Sevick-Muraca EM, editors. Proc SPIE 4250, p. 327-338. SPIE Photonics West 2001 Jan 19-25; San Jose, CA (Oral presentation,contributed)

CA7) Riley JD, Arridge SR, Chrysanthou Y, Dehgahani H, Hillman EMC, Schweiger M. The Radiosity Diffusion Model in 3D. In: Andersson-Engels S, Kaschke MF, editors. ECBO2001, Proc SPIE 4431, p. 153-164, Photon Migration, Optical Coherence Tomography, and Microscopy; 2001, June 18-21; Munich, Germany.

CA8) Hillman EMC et al, Biomedical applications of lasers: time resolved optical tomography, Rank Prize Fund Mini-symposium on Applications of Free Electron Lasers, Sept 2001, Grasmere, UK (Oral presentation, Invited student)

CA9) Gibson A, Dehghani H, Yusof RMd, Hillman EMC, Hebden JC, Schweiger M, Arridge SR, Delpy DT. Optical tomography of a realistic head-shaped phantom. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2002, April 6-10; Miami FL.

CA10) Hebden JC, Bland T, Hillman EMC, Gibson A, Everdell N, Delpy DT, Arridge SR. Optical tomography of the breast using a 32-channel time-resolved imager. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2002, April 6-10; Miami FL.


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CA11) Hebden JC, Hillman EMC, Gibson A, Everdell N, Yusof RMd, Delpy DT, Arridge SR, Austin T, Meek JH. Time resolved optical imaging of the newborn infant brain: Initial clinical results. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2002, April 6-10; Miami FL.

CA12) Hillman EMC, Arridge SR, Hebden JC, Delpy DT. Oxygen saturation and blood-volume derivation from multi-wavelength time-resolved optical tomography data. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2002, April 6-10; Miami FL. (Oral presentation, contributed)

CA13) Corlu A, Durduran T, Choe R, Lee K, Schweiger M, Hillman EMC, Arridge SR, Yodh AG. Optimum wavelengths in continuous-wave multi-spectral diffuse optical tomography. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2004, April 14-17; Miami FL.

CA14) Hillman EMC, Dunn AK, Boas DA, Laminar optical tomography of rat cortical activation: resolving depth-dependent hemodynamics from 0 to 2mm. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2004, April 14-17; Miami FL (Oral Presentation, contributed)

CA15) Hillman EMC, Devor A, Dale AM, Dunn AK, Boas DA. The use of depth-resolved optical imaging to separate cortical vascular compartments during functional activation. In: Brain ’05 proceedings, 2005, June 7-11; Amsterdam, Netherlands. (Poster)

CA16) Hillman EMC, Devor A, Dunn AK, Boas DA, 3D high-resolution optical imaging of cortical activation: Vascular compartment separation using spatio-temporal constraints and priors In: OSA European Conference on Biomedical Optics Technical Digest, Optical Society of America, Washington DC, 2005, June 7-13; Munich Germany. (Oral presentation, contributed, but selected for 30 minute Invited talk)

CA17) Hillman EMC, Devor A, Dunn AK, Skoch J, Bacskai BJ, Dale AM, Boas DA. Resolving the roles of vascular compartments during functional activation: A high-resolution 3D optical imaging study. In: Society for Neuroscience Conference proceedings, 2005, November 12-16; Washington DC. (Poster)

CA18) Hillman EMC, Devor A, Dunn AK, Boas DA. Laminar optical tomography: high-resolution 3D functional imaging of superficial tissues. Proc. SPIE 6143, 61431M, SPIE Medical Imaging, San Diego, CA 2006, February (Oral Presentation, Invited – presented by AH Hielscher due to plane cancellation)

CA19) Devor A, Hillman EMC, Nishimura N, Ulbert I, Narayanan SN, Teng I, Dunn AK, Boas DA, Kleinfeld D, Dale AM, Applying Optical Imaging to Study Neurovascular Coupling in Cerebral Cortex: From Populational Scale to Single-Cell Single-Vessel Measurements," In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2006, March 19-23; Fort Lauderdale FL.

CA20) Hillman EMC, *Bouchard M, Devor A, De Crespigny A, Boas DA, High-resolution functional optical imaging: sub-millimeter physiology of living tissue. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2006, March 19-23; Fort Lauderdale FL. (Oral presentation, contributed, but selected for 30 minute Invited talk)


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CA21) *Bouchard M, Ruvinskaya S, Boas DA and Hillman EMC. Video-rate two-photon microscopy of cortical hemodynamics in-vivo, In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2006, March 19-23; Ft Lauderdale FL. (Oral presentation, contributed)

Since Columbia University Hire:

CA22) Hillman EMC, Devor A, Boas DA. High Resolution Functional Optical Imaging of Living Tissues. IEEE Proceedings of the International Symposium on Biomedical Imaging (ISBI) 2006, April, Arlington VA (Oral Presentation, Invited)

CA23) Hillman EMC, Diffuse Optical Tomography, In: OSA Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference and Photonic Applications Systems Technologies (CLEO/QELS/PhAST), 2006, June 10; Long Beach CA. (Oral presentation, Invited)

CA24) Hillman EMC, High resolution functional optical imaging of exposed cortex in-vivo, Gordon Research Conference: Lasers in Medicine and Biology, Holderness, NH, July 2006. (Oral presentation, Invited)

CA25) Hillman EMC. Functional optical imaging of brain activation: a multi-scale, multi-modality approach, IEEE/NLM Life Science Systems and Application Workshop, NIH Bethesda, MD, July 2006. (Oral presentation, Invited)

CA26) Hillman EMC et al. High resolution functional optical imaging of rodent cortex: investigating mechanisms of functional activation, at ‘Optical Diagnostic Imaging from Bench to Bedside’ Technical Workshop at the National Institutes of Health 2006, September, NIH Bethesda, MD (Oral Presentation, Invited).

CA27) Hillman EMC and Cauli B, In-vivo and in-vitro: cellular and neurochemical mechanisms of somatosensory neurovascular coupling , HFSP meeting. July 2007, Brisbane, Australia (Poster)

CA28) Hillman EMC, Levenson RM. All-Optical Small Animal Anatomical Co-registration using Dynamic Contrast Enhancement (DyCE), AMI/SMI Joint Molecular Imaging Conference, 2007, September 7-11; Providence RI. (Oral presentation, contributed - paper highlighted as top 25 out of >900 abstracts after blind review)

CA29) *Burgess SA, *Yuan B, *Radosevich AJ, *Bouchard MB, Hillman EMC. “High-resolution 3D optical imaging of tissue”, IEEE Proceedings LEOS, Orlando FL, October 2007. (Oral presentation, Invited)

CA30) Hillman EMC, *Yuan B, *Burgess SA, *Iranmahboob AK, *Bouchard MB. Depth-resolved optical imaging of calcium sensitive dyes in somatosensory cortex in-vivo, Society for Neuroscience 2007. November 3-7; San Diego CA. (Poster)

CA31) Shah B, Moioli E, Hillman EMC, Mao JJ. In Vivo Tracking of Human Mesenchymal Stem Cells Labeled with Bioconjugated Quantum Dots, 54th Annual Meeting of the Orthopaedic Research Society 2008. March 2-5; San Francisco CA.

CA32) Hillman EMC, *Chen B, *Burgess SA, *Radosevich AJ, *Bouchard MB, *Iranmahboob AK, Das A, Cauli B. Multidimensional functional optical imaging of the brain. In:


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OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2008. March 16-19; St Petersberg FL. (Oral presentation, Invited)

CA33) Hillman EMC, *Bouchard MB, *Burgess SA, Gossage K, Mansfield JR, Levenson RM, Dynamic Molecular Imaging: Anatomical Co-registration and Dynamic Contrast Enhancement. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2008. March 16-19; St Petersberg FL. (Oral presentation, contributed)

CA34) *Bouchard MB, *Burgess SA, *Moussazadeh P, *Radosevich AJ, Wuskell JP, Loew LM, Pertsov A, Hillman EMC. Electrical and metabolic imaging of cardiac ischemia In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2008. March 16-19; St Petersberg FL. (Poster)

CA35) *Yuan B, Hillman EMC. Feasibility of 3-D Frequency-Domain Fluorescence Lifetime Imaging based on Laminar Optical Tomography. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2008. March 16-19; St Petersberg FL. (Oral presentation, contributed)

CA36) *Radosevich AJ, *Bouchard MB, *Burgess SA, *Stolper R, *Chen B, Hillman EMC. Hyperspectral in-vivo two-photon microscopy of intrinsic fluorophores. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2008. March 16-19; St Petersberg FL. (Oral presentation, contributed)

CA37) *Burgess SA, *Yuan B, *Bouchard MB, Ratner D, Hillman EMC. Simultaneous Multi-Wavelength Laminar Optical Tomography Imaging of Skin Cancer. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2008. March 16-19; St Petersberg FL. (Oral presentation, contributed)

CA38) *Iranmahboob AK, Hillman EMC. Diffusion vs. Monte Carlo for Image Reconstruction in Mesoscopic Volumes. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, Washington DC, 2008. March 16-19; St Petersberg FL. (Poster)

CA39) Hillman EMC, Cauli B. In-vitro & in-vivo: Mechanisms of cortical neuro-vascular-metabolic coupling HFSP meeting. July 2008, Berlin, Germany. (Poster)

CA40) *Chen BR, *Burgess SA, *Radosevich AJ, *Bouchard MB, Cauli B, Hillman EMC, Multi-Scale In-Vivo Imaging of Neurovascular Coupling, Cerebral blood flow and metabolism, 2008 Gordon Research Conference on Brain Energy Metabolism and Blood Flow, August 2008, Andover, NH (Poster, won student travel stipend).

CA41) Hillman EMC, Vascular compartment dynamics during neuronal activation, 2008 Gordon Research Conference on Brain Energy Metabolism and Blood Flow, August 2008, Andover, NH . (Oral presentation, Invited)

CA42) Hillman EMC, Levenson RM, *Amoozegar CB, *Chen BR, *Burgess SA, *Bouchard MB, Dynamic molecular imaging of organ function, Proceedings of the World Molecular Imaging Congress, September 10, 2008, Nice France. (Poster)

CA43) Hillman EMC et al, Optical Imaging of transmural cardiac propagation, BMES Annual Meeting, October 2nd 2008, St Louis MO. (Oral Presentation, Invited: Cardiac Imaging session)


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CA44) Hillman EMC. Mouse Organ Imaging, In: Proceedings of OSA Frontiers in Optics (FiO) October 19, 2008, Rochester, NY. (Oral presentation, Invited ‘Imaging of Mice and Men’ session)

CA45) Hillman EMC, *Chen B, *Burgess SA, *Radosevich AJ, *Bouchard MB, Iranmahboob AK, Das A, Cauli B. Multidimensional functional optical imaging of the brain. In: Proceedings of OSA Frontiers in Optics (FiO) Oct 19, 2008, Rochester, NY. (Oral presentation, Invited ‘Best of the Topicals’ session)

CA46) Karagiannis A, Gallopin T, Dávid C, Battaglia D, Geoffroy H, Rossier J, Hillman EMC, Staiger J, Cauli B. Classification of NPY-expressing neocortical interneurons. Ladislav Tauc Conference 2008. December 2008, Gif sur Yvette, France.

CA47) Hillman EMC, Photons for functional imaging: Microscopy and optical imaging technologies for in-vivo applications. Proceedings of the Dodd-Walls Center for Quantum Science and Technology Symposium, December 8th, 2008, Queenstown, New Zealand. (Oral presentation, Invited Keynote)

CA48) Karagiannis A, Gallopin T, Dávid C, Battaglia D, Geoffroy H, Rossier J, Hillman EMC, Staiger J, Cauli B. Identification and characterization of putative neurovascular regulators in the rat barrel cortex, EMBO workshop, "Cortical interneurons in health and disease". June 2009. Mallorca, Spain.

CA49) *Bouchard MB, *Chen BR, *Burgess SA, Hillman EMC, Ultra-fast multiwavelength CCD-based optical imaging. Engineering Conferences International meeting: Advances in Optics for Biotechnology, Medicine and Surgery XI. June 2009, Burlington VT. (Poster)

CA50) *Chen BR, *McCaslin AFH, *Bouchard MB, *Radosevich AJ, *Burgess SA, Cauli B, Hillman EMC, High speed two-photon microscopy of reactive cortical cells in vivo. Engineering Conferences International meeting: Advances in Optics for Biotechnology, Medicine and Surgery XI. June 2009, Burlington VT. (Poster)

CA51) *Bordier, C, *Iranmahboob A, *Burgess SA, Hillman EMC, Monte Carlo Modeling for 3D Optical Imaging of Mesoscopic Volumes. Engineering Conferences International meeting: Advances in Optics for Biotechnology, Medicine and Surgery XI. June 2009, Burlington VT. (Poster)

CA52) *Amoozegar CB, *McCaslin AFH, *Bouchard MB, Blaner WS, Hillman EMC, Non-invasive Evaluation of Organ Function Using Dynamic Contrast Enhanced Molecular Imaging. Engineering Conferences International meeting: Advances in Optics for Biotechnology, Medicine and Surgery XI. June 2009, Burlington VT. (Poster)

CA53) *Grosberg LE, *Radosevich AJ, *Bouchard MB, *Chen BR, Hillman EMC, Hyperspectral Two-Photon Microscopy for 3D Instant Histology. Engineering Conferences International meeting: Advances in Optics for Biotechnology, Medicine and Surgery XI. June 2009, Burlington VT. (Poster)

CA54) *Burgess SA, *Bouchard MB, *Bordier C, *Chen BR, Hillman EMC, Fluorescence Laminar Optical Tomography for Imaging Skin. Engineering Conferences International meeting: Advances in Optics for Biotechnology, Medicine and Surgery XI. June 2009, Burlington VT. (Poster)


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CA55) Hillman EMC, In vivo optical imaging of animal disease models: From micro to macro. Engineering Conferences International meeting: Advances in Optics for Biotechnology, Medicine and Surgery XI. June 2009, Burlington VT. (Oral presentation, Invited)

CA56) Mansfield J, Aronow LA, Curtis A, Hillman EMC, Krucker T, Levenson RM, In Vivo Fluorescence Kinetic Imaging for Improved Contrast and Studies of Temporal Biodistribution. Proceedings of the World Molecular Imaging Congress, September 25, 2009, Montreal, CA.

CA57) *Chen BR, *Bouchard MB, *McCaslin AFH, Hillman EMC, Characterization of cortical vascular compartment-specific hemodynamics during somatosensory stimulation. Society for Neuroscience Annual Meeting, October 2009, Chicago IL. (Poster)

CA58) *McCaslin AFH, *Chen BR, *Radosevich AJ, Hillman EMC, In-vivo 3D morphology of astrocyte-vasculature interactions in the somatosensory cortex. Society for Neuroscience Annual Meeting, October 2009, Chicago IL. (Poster)

CA59) Christiano AM, McGrath JA, Hillman E, Philipone E, Ventura K, Ishida-Yamamoto, Reduced intensity conditioning and allogeneic stem cell transplantation in Recessive Dystrophic Epidermolysis Bullosa. 69th Annual Meeting of the Society-of-Investigative-Dermatology, MAY 06-09, 2009, Journal of Investigative Dermatology 129: S56-S56 336 Suppl. 1 April 2009

CA60) Baik AD, Lu XL, Hillman EMC, Dong C, Guo XE, Dynamic Pseudo-3D Whole-Cell and Actin/Microtubule Network Deformation of Osteocytes Under Fluid Shear Flow. Orthopaedic Research Society Annual meeting, March 6-9, 2010, New Orleans LA.

CA61) *Grosberg LE, *Radosevich AJ, Asfaha S, Yang X, Wang TJ, Hillman EMC, 3D visualization of intrinsic contrast in neoplastic colon tissue using hyperspectral two-photon microscopy. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, April 11-14 2010; Miami FL (Poster. - Winner of Best Student Poster Prize)

CA62) *Sun R, *Bouchard MB, *Burgess SA, *Radosevich AJ, Hillman EMC A Low-cost, Portable System for High-Speed Multispectral Optical Imaging. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, April 11-14 2010; Miami FL. (Poster)

CA63) *Burgess SA, Ratner D, *Chen BR, Hillman EMC, Fiber-Optic and Articulating Arm Implementations of Laminar Optical Tomography for Clinical Applications. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, April 11-14 2010; Miami FL. (Oral presentation, Contributed)

CA64) *Bouchard MB, Grosberg LE, Burgess SA, Hillman EMC, Laser-Scanning Intersecting Plane Tomography (L-SIPT) for high speed 3D optical imaging and microscopy. In: OSA Biomedical Topical Meetings, OSA Technical Digest, Optical Society of America, April 11-14 2010; Miami FL. (Oral presentation, Contributed)

CA65) Hillman EMC, Optical neuroimaging, 2010 Gordon Research Conference on Lasers in Medicine and Biology, July 25–30, Holderness, NH. (Oral presentation, Invited)

CA66) Plaisier F, Karagiannis A, *Burgess SA, Chausson P, Hamel E, Hillman EMC, Cauli B, Identification of putative vasoconstricting neurons in the cerebral cortex. Federation of European Neuroscience Societies (FENS), July 2010, Amsterdam.


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CA67) Karagiannis A, Plaisier F, Gallopin T, David C, Geoffroy H, Hillman EMC, Staiger JF, Cauli B. Lactate excites cortical neurons via ATP sensitive K+ channels closure. Federation of European Neuroscience Societies meeting, July 2010, Amsterdam, The Netherlands.

CA68) Baik AD, Lu XL, Hillman EMC, Dong C, Guo XE, Pseudo-3D Real-Time Tracking of Osteocyte Whole-Cell and Actin/Microtubule Network Deformations under Fluid Shear Flow. 6th World Congress on Biomechanics, August 2010, Singapore.

CA69) *L’Heureux B, *McCaslin AFH, *Bouchard MB, *Chen BR, Cauli B, Hillman EMC, Studying Metabolism and the Lactate Shuttle In-Vivo Using Optical Imaging and Microscopy, Gordon Research Conference on Brain Energy Metabolism and Blood Flow August 2010. Andover, NH. (Poster)

CA70) *Chen BR, *Bouchard MB, *McCaslin AFH, *Burgess SA, Cauli B, Hillman EMC, Characterization of cortical vascular compartment-specific hemodynamics during somatosensory stimulation, Gordon Research Conference on Brain Energy Metabolism and Blood Flow August 2010. Andover, NH. (Poster)

CA71) Karagiannis A, Plaisier F, Gallopin T, David C, Geoffroy H, Hillman EMC, Staiger JF, Cauli B. Lactate excites cortical neurons via ATP sensitive K+ channels closure. Gordon Research Conference on Brain Energy Metabolism and Blood Flow August 2010. Andover, NH.

CA72) *Bouchard MB, Hillman EMC, Laser-Scanning Intersecting Plane Tomography for High Speed, translationless 3D Microscopy, Society of General Physiologists, New Optical Methods in Cell Physiology, September 2010, MBL Woods Hole, MA. (Poster - won $500 travel stipend)

CA73) *Grosberg LE, *Radosevich AJ, *Bouchard MB, Hillman EMC, Characterization of intrinsic contrast in intact tissues using hyperspectral two-photon microscopy, Society of General Physiologists, New Optical Methods in Cell Physiology, September 2010, MBL Woods Hole, MA. (Poster)

CA74) *Chen BC, *McCaslin AFH, *L’Heureux B, *Bouchard MB, Hillman EMC, Two-Photon Microscopy of Neurovascular Dynamics, Society of General Physiologists, New Optical Methods in Cell Physiology, September 2010, MBL Woods Hole, MA. (Poster - won $500 travel stipend)

CA75) Hillman EMC, Imaging everything: Harnessing endogenous and exogenous contrast in- vivo, Society of General Physiologists, New Optical Methods in Cell Physiology, September 2010, MBL Woods Hole, MA. (Oral presentation, Invited)

CA76) Hillman EMC et al, Opportunities for Biophotonics-based approaches in Drug Discovery & Development, International Congress on Biophotonics 25-27 Sept 2010, Quebec City, Canada (Oral Presentation, Invited)

CA77) Hillman EMC and *L’Heureux B, Redox Imaging and metabolism, International IFR83 annual meeting “Oxidative Metabolism in Health and Diseases”, Sept 27-28, 2010, Paris, France (Oral presentation, Invited - Post-doctoral fellow Barbara L’Heureux attended on my behalf)

CA78) Karagiannis A, Plaisier F, Gallopin T, David C, Geoffroy H, Staiger JF, Roeper J, Hillman EMC, Cauli B. Lactate excites cortical neurons via ATP sensitive K+ channels closure,


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International IFR83 annual meeting “Oxidative Metabolism in Health and Diseases”, September 2010, Paris, France.

CA79) Plaisier F, Karagiannis A, *Burgess S, Chausson P, Hamel E, Hillman EMC, Cauli B. Identification of putative vasoconstricting neurons in the cerebral cortex. International IFR83 annual meeting “Oxidative Metabolism in Health and Diseases”, September 2010, Paris, France.

CA80) Hillman EMC, Cauli B. A push-pull model of neurovascular coupling derived using combined in-vivo and in-vitro approaches. HFSP meeting, October-November 2010, Thiruvananthapuram, India. (Poster)

CA81) Karagiannis A, Plaisier F, Gallopin T, David C, Geoffroy H, Staiger JF, Hillman EMC; Roeper J, Cauli B. Lactate excites cortical neurons via ATP sensitive K+ channels closure. Society for Neuroscience meeting, November 2010, San Diego, CA.

CA82) Hillman EMC, New Visions for Optical Imaging. Royal Society Conference: Making light work: Illuminating the future of biomedical optics. Nov 8-9 2010. Kavli Royal Society Centre, Buckinghamshire, UK. (Oral presentation, Invited)

CA83) Hillman EMC, Understanding neurovascular coupling with intravital microscopy and optical imaging, Neurotechniques Symposium at the Italian Academy for Advanced Studies in America at Columbia University, Dec 3rd 2010. New York (Oral presentation, Invited)

CA84) Plaisier F, Karagiannis A, *Burgess S, Chausson P, Hamel E, Hillman EMC, Cauli B. Identification of putative vasoconstricting neurons in the cerebral cortex. Annual Meeting of the French Club of Glial Cells, December 2010, Paris, France.

CA85) Karagiannis A, Plaisier F, Gallopin T, David C, Geoffroy H, Staiger JF, Roeper J, Hillman EMC, Cauli B. Lactate excites cortical neurons via ATP-sensitive K+ channels closure [selected talk], Meeting of French Society for Cerebral Blood Flow and Metabolism, January 2011, Caen, France .

CA86) Hillman EMC, In-vivo optical imaging and microscopy of neurovascular coupling. Advanced Imaging Methods Workshop, Jan 19-21 2011, Berkeley CA (Oral presentation, Invited)

CA87) Cayce JM, *Bouchard M, *Chen B, Jansen ED, Hillman EMC, Mahadevan-Jansen A. Optical imaging of signals evoked by infrared neural stimulation of the rat brain. Proc SPIE paper 7883G-146, SPIE Photonics West, Jan 2011, San Francisco CA.

CA88) Hillman EMC, The physiological limits of spatial and temporal resolution in fMRI, Ultra High Field Workshop sponsored by the International Society of Magnetic Resonance in Medicine (ISMRM), Feb. 20-23, 2011, Lake Louise, Canada. (Oral presentation, Invited)

CA89) *De Leo SE, *Chen BR, *Kozberg M, Gil O, Canoll P, Hillman EMC, ‘In-vivo optical imaging of glioma pathogenesis’ Brain 2011, May 24-28, Barcelona, Spain (Oral presentation, contributed – worn student registration waiver and travel stipend)

CA90) *Kozberg M, *DeLeo SE, *Bouchard MB, Hillman EMC, ‘Optical imaging of neurovascular coupling during neonatal development’, Brain 2011, May 24-28, Barcelona, Spain (Poster)

CA91) Hillman EMC, Imaging the Neurovascular Unit, Teaching session on Neurovascular Unit at Brain 2011, May 24-28, Barcelona, Spain (Oral presentation, Invited)


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CA92) Plaisier F, Karagiannis A, Chausson P, Jarlier F, McCaslin AFH, Toussay X, Hamel E, Hillman EMC, Cauli B. Identification and characterization of parenchymal prostaglandinergic cells in the rat cerebral cortex, Brain 2011, May 24-28, Barcelona, Spain (Poster)

CA93) Karagiannis A, Plaisier F, Gallopin T, Geoffroy H, David C, Jarlier F, Nomura S, Guiot E, *L'Heureux B, *Burgess S, Lambolez B, Staiger JF, Seino S, Hillman EMC, Roeper J, Cauli B. Cortical neurons like glucose but they love eating lactate, Brain 2011, May 24-28, Barcelona, Spain (Oral presentation, contributed)

CA94) *Grosberg L, Hillman EMC, Dual-beam two-photon microscopy for simultaneous fast acquisition of two focal planes, SPIE / OSA European Conference on Biomedical Optics, 2011, 22-26 May, Munich, Germany. (Oral presentation, contributed, but selected for 30 minute Invited talk)

CA95) *Bouchard MB, Hillman EMC, 3D Laser-Scanning Intersecting Plane Tomography (L-SIPT) for High Speed, Translationless Volumetric Microscopy, SPIE / OSA European Conference on Biomedical Optics, 2011, 22-26 May, Munich, Germany (Oral presentation, contributed)

CA96) Baik AD, Qiu J, Hillman EMC, Dong C, Guo XE, Quasi-3D Dynamics of Actin and Microtubule Networks in Individual MLO-Y4 Osteocytes under Steady and Oscillatory Flow, American Society for Bone and Mineral Research 2011.

CA97) *Muldoon TJ, *Burgess SA, Ratner D, *Chen BR, Hillman EMC. Analysis of skin lesions with Laminar Optical Tomography, ECI Advances in Optics for Biotechnology, Medicine and Surgery XII. June 2011, Naples FL. (Poster)

CA98) *Rayshubskiy S, *Bouchard MB, Mikell C, Youngerman B, Otten M, Hillman EMC. Ultrafast multispectral optical imaging of the human cortex during neurosurgery, ECI Advances in Optics for Biotechnology, Medicine and Surgery XII. June 2011, Naples FL. (Poster)

CA99) Hillman EMC, (Brain) Imaging (Presentation and Think Tank participation). Kavli, Allen, Gatsby meeting on Nano-Neuro, Sept 10-13, 2011, Royal Society Kavli Center, UK, (Oral presentation, Invited)

CA100) Lacroix A, Plaisier F, Karagiannis A, Chausson P, Jarlier F, *McCaslin AFH, Toussay X, Hamel E, Hillman EMC, Cauli B. Identification and characterization of parenchymal prostaglandinergic cells in the rat cerebral cortex. Meeting of the French Society for the Study of Blood Brain Interfaces, October 2011, Paris, France.

CA101) Karagiannis A, Plaisier F, Gallopin T, Geoffroy H, David C, Jarlier F, Nomura S, Guiot E, *L'Heureux B, *Burgess S, Lambolez B, Staiger JF, Seino S, Hillman EMC, Roeper J, Cauli B. Cortical neurons like glucose but they love eating lactate, Meeting of the French Sociecty for the Study of Blood Brain Interfaces, October 2011, Paris, France.

CA102) Hillman EMC and Kyle A, Biomedical Engineering Senior Design at Columbia University, ‘Global Immersion snapshot panel’ at the NCIIA / BMEIdea Alliance Meeting, BMES, October 2011, Hartford CT. (Oral Presentation, contributed)

CA103) Hillman EMC, Phantoms for quantitative multimodal imaging, at ‘Standards for Phantoms for the Performance Evaluation and Validation of Optical Medical Imaging Devices’ NIST Conference, Catholic University of America, Nov 7-8th 2011, Washington DC. (Oral Presentation, Invited)


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CA104) *Rayshubskiy A, *Bouchard MB, Mikell C, Youngerman B, *Timerman D, Otten D, Hillman EMC, Multispectral optical imaging of resting state fluctuations in the human cortex during neurosurgery, Society for Neuroscience Annual Meeting, November 2011, Washington DC. (Poster)

CA105) *Timerman D, *Chen BR, *Rayshubskiy A, Kozberg M, Hillman EMC, Optical imaging of resting state neurovascular coupling, Society for Neuroscience Annual Meeting, November 2011, Washington DC. (Poster)

CA106) *Chen BR, *L’Heureux, *Bouchard MB, Castelli M, Hillman EMC, A multi-phase model of neurovascular coupling, Society for Neuroscience Annual Meeting, November 2011, Washington DC. (Poster)

CA107) *Kozberg M, *Chen BR, *De Leo S, Hillman EMC, In-vivo 3D morphology of cerebral vasculature during neonatal development, Society for Neuroscience Annual Meeting, November 2011, Washington DC. (Poster)

CA108) *Amoozegar C, Persigehl T, *Bouchard MB, Schwartz LH, Hillman EMC, “Comparison of Optical and MRI dynamic contrast imaging in liver pathologies”, RSNA, December 2011 (Oral presentation, contributed)

CA109) Lacroix A, Plaisier F, Karagiannis A, Chausson P, Jarlier F, *McCaslin AFH, Toussay X, Hamel E, Hillman EMC, Cauli B. Identification and characterization of parenchymal prostaglandinergic cells in the rat cerebral cortex, Meeting of French Society for Cerebral Blood Flow and Metabolism, January 2012, Paris, France. (Oral presentation, contributed)

CA110) Karagiannis A, Plaisier F, Gallopin T, Geoffroy H, David C, Jarlier F, Nomura S, Guiot E, *L'Heureux B, *Burgess S, Lambolez B, Staiger JF, Seino S, Hillman EMC, Roeper J, Cauli B. Cortical neurons like glucose but they love eating lactate, Meeting of French Society for Cerebral Blood Flow and Metabolism, January 2012. Paris, France. (Oral presentation, contributed)

CA111) Cayce J, *Bouchard MB, Jansen DE, Hillman EMC, Mahadevan-Jansen A, “Parametric evaluation of calcium waves evoked by infrared neural stimulation”, Paper 8207G-157 of Conference 8207G, 23 January 2012, SPIE Photonics West. (Oral presentation, contributed)

CA112) Hillman EMC, *Grosberg LE, *Chen BC, *Klibaite U, *Galwaduge PT, ‘Multi-plane two photon microscopy for high speed 3D neuroimaging’ Paper 8207G-162, SPIE Photonics West, 23 January 2012, San Francisco CA. (Oral presentation, Invited) *Featured in Nature Photonics News and Views of as a conference highlight.

CA113) Hillman EMC, ‘Hot-Topics: In-vivo Microscopy: a New Window on the Brain’, SPIE Photonics West, 23 January 2012, San Francisco CA (Oral presentation, Invited)

CA114) Stoyanov D, *Rayshubskiy A, Hillman EMC, “Robust registration of multispectral images of the cortical surface in neurosurgery'', IEEE ISBI, May 2012, Barcelona, Spain. (Poster)

CA115) Hillman EMC, *Kozberg MG et al, Novel in vivo imaging techniques for studying the neurovascular unit Imaging and novel diagnostics, 7th International Symposium on Neuroprotection and Neurorepair Potsdam Neurotrama and Repair, 2nd - 5th of May 2012,


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Potsdam, Germany (Oral Presentation, Invited - MD/PhD student Mariel Kozberg presented in my place).

CA116) *Rayshubskiy A, *Liu A, *Shaik M, *Chen BR, Hillman EMC, In-vivo cellular resolution of flavoprotein and NADH autofluorescence dynamics in the rat somatosensory cortex. Gordon Research Conference on Brain Energy Metabolism & Blood Flow, August 2012, Waterville ME. (Poster)

CA117) *Kozberg MG, *Chen BR, *Bouchard MB, Hillman EMC, The development of neurovascular coupling in the neonatal brain. Gordon Research Conference on Brain Energy Metabolism & Blood Flow, August 2012, Waterville ME. (Poster) [Awarded full travel fellowship]

CA118) *Chen BR, *Kozberg MG, *Bouchard MB, Hillman EMC. The role of the vascular endothelium in neurovascular coupling. Society for Neuroscience Annual Meeting, October 2012, New Orleans LA. (Poster)

CA119) *Rayshubskiy A, *Liu A, *Shaik M, *Chen BR, Hillman EMC, In-vivo cellular resolution of flavoprotein and NADH autofluorescence dynamics in the rat somatosensory cortex. Society for Neuroscience Annual Meeting, October 2012, New Orleans, LA. (Poster)

CA120) *Kozberg MG, *Chen BR, Hillman EMC, Blood pressure confounds in the study of neonatal brain function. Society for Neuroscience Annual Meeting, October 2012, New Orleans, LA (Poster)

CA121) Hillman EMC, In-vivo optical imaging and microscopy of neurovascular coupling, at Photonic Imaging in Neuroscience Workshop, Marseille, France, 1-3rd Oct 2012 (Oral Presentation, Invited)

CA122) Hillman EMC, ‘Optical Imaging and Microscopy of the Living Brain’ at Optical Imaging and Microscopy of the Living Brain, OSA Frontiers in Optics, Rochester NY, 14-18 Oct 2012 (Oral Presentation, Invited)

CA123) Hillman EMC, Plenary: ‘Optical Neuroimaging’, at OSA ‘Optics in the Life Sciences’ congress, Hawaii, 14-18 April 2013.

CA124) Hillman EMC, ‘In-vivo dynamic and hyperspectral microscopy’, American Association of Anatomists ‘Experimental Biology 2013’ Meeting, Boston MA, 20-24th April 2013 (Oral Presentation, Invited)

CA125) Hillman EMC, ‘Small Animal Imaging with Dynamic Contrast (DyCE)’, PerkinElmer Revolutionaries for Global Health Summit (RGHS), 8-9th May 2013 (Oral Presentation, Invited as inventor of licensed technology)

CA126) *Kozberg MG, *Grosberg LE, Hillman EMC, ‘Postnatal development of neurovascular coupling at a cellular and microvascular level’, Brain 2013, 20-23rd May 2013, Shanghai, China. (Poster).

CA127) Hillman EMC, ‘Cellular, vascular and functional development of the brain', ‘Highlights from the Journal of Cerebral Blood Flow and Metabolism’ special session at Brain 2013, 20-23rd May 2013, Shanghai, China. (Oral Presentation, Invited)


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CA128) Hillman EMC, ‘Exposed-cortex optical mapping of brain function: From animal to man’, Society for Brain Mapping and Therapeutics, 12-14th May 2013, Baltimore MD (Oral Presentation, Invited)

CA129) *Chow D, *Kozberg MG, Filippi C, Hillman EMC, ‘Visualization of a Stroke in Progress: A new in-vivo optical imaging technique for studying acute middle cerebral artery territory infarction’, Radiological Society of North America (RSNA), December 2013.

CA130) *Voleti V, *Bouchard MB, Lacefield C, Bruno RM, Hillman EMC, ‘High-speed 3D in-vivo imaging of neuronal populations using laser scanning intersecting plane tomography’, Society for Neuroscience Annual Meeting, October 2013, San Diego, LA (Poster)

CA131) Hillman EMC, *Chen BR, *Kozberg MG, *Bouchard MB, ‘A novel mechanism for fast neurovascular coupling’, Society for Neuroscience Annual Meeting, October 2013, San Diego, LA (Digital Poster).

CA132) *Kozberg MG, *Rayshubskiy A, *Chen BR, *Bouchard MB, Hillman EMC, ‘Imaging the co-development of hemodynamic and neuronal receptive fields in the neonatal brain’, Society for Neuroscience Annual Meeting, October 2013, San Diego, LA (oral presentation)

CA133) *Ma Y, *Rayshubskiy A, *Kim SH, *Timerman D, Kozberg MG, Hillman EMC, ‘Are resting state and stimulus-evoked neurovascular coupling different?’, Society for Neuroscience Annual Meeting, October 2013, San Diego, LA (poster)

CA134) *Kim S, *Voleti V, *Ma Y, *Ramirez E, *Kozberg MG, *Bouchard MB, *Chen BR, *Rayshubskiy A, Hillman EMC, ‘Longitudinal assessment of resting state functional connectivity variance in the rat brain’, Society for Neuroscience Annual Meeting, October 2013, San Diego, LA (poster).

CA135) Hillman EMC, ‘Functional imaging contrast in infants and children’, Small Workshop on Building Bridges to Facilitate Understanding and Treating ASD, Sackler Foundation, 18-19th October 2013, New York NY. (Oral Presentation, Invited).

CA136) Hillman EMC, ‘In-vivo dynamic and hyperspectral microscopy’, 7th Annual Workshop on Advanced TCSPC Techniques, 21-22 October 2013, Bethesda MD, (Oral Presentation, Invited).

CA137) *Chow D, *Kozberg MG, Filippi C, Hillman EMC, ‘Visualization of a Stroke in Progress: A new in-vivo optical imaging technique for studying acute middle cerebral artery territory infarction’, Radiological Society of North America (RSNA), December 2013. (poster)

CA138) Hillman EMC, ‘Depth and Speed: What are the Limits?’, OSA Spatially Precise Optogenetics at Depth Incubator Meeting, 8-10th December 2013 in Washington, DC. (Oral Presentation, Invited)

CA139) Lunardi CN, *Gomes, AJ, *Palepu S, *Galwaduge T, Hillman EMC, ‘Synthesis and in-vivo characterization of fluorescent polymeric nano/microparticles incorporating cresyl violet. Materials Research Society Fall meeting, Nov 30-Dec5th, 2013, Boston MA (poster).

CA140) Hillman EMC, ‘Intraoperative imaging of the human brain and fast 3D whole-field in-vivo microscopy’, 11th Advanced Imaging Methods Workshop, UC Berkeley, 29-31st January 2014, (Oral Presentation, Invited)


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CA141) Hillman EMC, ‘Hyperspectral and Dynamic contrast: What your eyes can’t see’, NextMed, Medicine meets Virtual Reality (MMVR21) meeting, 19-22nd February 2014, Manhattan Beach CA. (Oral Presentation, Invited Plenary)

CA142) *Galwaduge PT, *Grosberg LE, *Kim SH, *Shaik MA and Hillman EMC, ‘Signal-Based Adaptive Optics Optimization for in-vivo Two-Photon Microscopy of the Brain’, OSA Biomed, April 2014, Miami, FL (poster)

CA143) *Voleti V, *Bouchard MB, Hillman EMC, ‘Design of a second generation Laser Scanning Intersecting Plane Tomography (L-SIPT) system’, OSA Biomed, April 2014, Miami, FL (oral presentation)

CA144) Hillman EMC, ‘Brain Blood Flow and Metabolism; Neurovascular Mechanisms and Postnatal Brain Development’, ISOTT (International Society on Oxygen Transport to Tissue), June 28th, 2014, London (Keynote)

CA145) Hillman EMC, ‘Methods for ultra-fast 3D volumetric microscopy in-vivo’ at the ‘Montreal Light Microscopy Course, 14-18th July 2014 (plenary)

CA146) Hillman EMC. ‘Multi-scale optical imaging and photo-manipulation of the living brain’, ‘Imaging in 2020, Imaging the Immune System: Look into the long term future of Imaging’, September 21 – 25, 2014, Jackson Hole WY (invited)

CA147) *Kim SH, *Ma Y, *Shaik MA, *Kozberg MG, *Voleti V, *Yang K, Hillman EMC, 'Comparison of neuronal and hemodynamic resting state functional connectivity mapping in awake mouse brain', Society for Neuroscience Annual Meeting, November 2014, Washington, DC. (poster)

CA148) *Ma Y, *Kozberg MG, *Kim SK, Hillman EMC, 'Assessing cortical neurovascular coupling in the presence and absence of stimulation', Society for Neuroscience Annual Meeting, November 2014, Washington, DC. (poster)

CA149) *Kozberg MG, *Ma Y, *Shaik MA, *Lunardi CA, *Gomes AJ, Tfouni E, Hillman EMC, 'Mechanisms of neurovascular maturation in the developing brain', Society for Neuroscience Annual Meeting, November 2014, Washington, DC. (poster)

CA150) *Voleti V, *Bouchard MB, Mendes CS, Lacefield C, Grueber WB, Mann RS, Bruno RM, Hillman EMC, ‘High-speed, volumetric imaging of behaving organisms using swept oblique light sheet (SOLiS) microscopy’, Society for Neuroscience Annual Meeting, November 2014, Washington, DC. (poster)

CA151) *Portes JP, *Amoozegar CB, *Chen BR, *Kozberg MG, *Shaik MS, Hillman EMC, ‘A new non-linear model of the fMRI BOLD response’, Society for Neuroscience Annual Meeting, November 2014, Washington, DC. (poster)

CA152) *Galwaduge P, *Kim SH, *Grosberg LE, Hillman EMC, ‘Signal-based adaptive optics two-photon microscopy of in-vivo mouse brain', Society for Neuroscience Annual Meeting, November 2014, Washington DC. (poster)

CA153) *Shaik MA, *Chung DY, *Kozberg MG, Hillman EMC, ‘Assessing the contribution of endothelial mechanisms in functional neurovascular coupling’, Society for Neuroscience Annual Meeting, November 2014, Washington, DC. (poster)


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CA154) *Chung DY, *Shaik M, *Kim SH, *Kozberg MG, and Hillman EMC, 'Assessment of cortical vascular responsivity to calcium channel blockers in the context of vasospasm after subarachnoid hemorrhage’, Society for Neuroscience Annual Meeting, November 2014, Washington, DC. (poster)

CA155) Hillman EMC, ‘Optics in Neuroscience’, Special OSA-sponsored symposium to celebrate ‘The International Year of Light; at the AAAS annual meeting, San Jose CA, Feb 2015. (invited)

CA156) Hillman EMC, ‘Dynamic in-vivo optical imaging and microscopy of the living brain’, SPIE Photonics West, San Francisco CA, Feb 2015. (invited)

CA157) *Voleti V, *Bouchard MB, Lacefield C. Bruno RM, Hillman EMC, ‘Fast, Volumetric Imaging of In Vivo Brains with Swept Confocally Aligned Planar Excitation (SCAPE) Microscopy’, OSA Optics and the Brain, Vancouver, April 2015, (oral presentation).

CA158) *Shaik MA, *Kim SH, *Zhao HT, Hillman EMC, ‘Simultaneous Multi-Region Imaging Of Neuronal Activity, Hemodynamics And Speckle Flow In Awake Mice.’, OSA Optics and the Brain, Vancouver, April 2015, (oral presentation).

CA159) *Patel K, *Galwaduge PT, Chen K, Dowd M, Bates G, Patel VA, Taub R, Hillman EMC, ‘High Resolution Fluorescence Imaging of Human Hand Pharmacokinetics using a Low-Cost Flatbed Scanner’, OSA Optical Molecular Probes, Imaging and Drug Delivery, Vancouver, April 2015, (oral presentation).

CA160) *Galwaduge PT, *Kim SH, *Grosberg LE, Hillman EMC, ‘Simple Signal-Based Wavefront Correction for In-Vivo Two-Photon Microscopy in Mouse Brain’, OSA Optics and the Brain, Vancouver, April 2015, (oral presentation).

CA161) Hillman EMC, *Bouchard MB, *Voleti V, ‘Swept Confocally-aligned Planar Excitation' (SCAPE) Microscopy for High Speed Volumetric Imaging in Behaving Animals’, Optical Molecular Probes, Imaging and Drug Delivery, Vancouver, April 2015, (invited)

CA162) *Ma Y, *Kozberg MG, *Kim SH, Hillman EMC, ‘Comparing stimulus-evoked and resting-state neurovascular coupling with simultaneous electrophysiology, wide-field neuronal GCaMP and hemodynamic imaging’, ISCBFM Brain 2015, Vancouver, June 2015, (poster).

CA163) *Zhao HT, *Chow D, *Kozberg MG, *Shaik MA, *Kim SH, Hillman EMC, ‘Optical imaging of neural activity, oxygenation and blood flow dynamics during the progression of acute stroke’, ISCBFM Brain 2015, Vancouver, June 2015, (poster).

CA164) *Kim SH, *Shaik MA, *Ma, Y, *Zhao HT, *Kozberg MG, *Voleti V, Hillman EMC, ‘Hemodynamic and neuronal resting state functional connectivity mapping in the awake mouse brain’, ISCBFM Brain 2015, Vancouver, June 2015, (poster).

CA165) *Shaik MA, *Kim SH, *Zhao HT, Hillman EMC, ‘The influence of endothelial dysfunction on neurovascular coupling’, ISCBFM Brain 2015, Vancouver, June 2015, (poster).

CA166) *Shaik MA, *Kim SH, *Ma Y, *Zhao HT, Hillman EMC, ‘The effects of endothelial dysfunction on neural activity, hemodynamics and neurovascular coupling’ SFN annual meeting, Chicago, 2015 (poster).


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CA167) *Zhao H, *Chow D, *Kozberg MG, *Shaik MA, *Kim SH, Hillman EMC, ‘Capturing the dynamics of neuronal activity, brain oxygenation and brain blood flow during acute cortical stroke’, SFN annual meeting, Chicago, 2015 (poster).

CA168) Hillman EMC, *Voleti V, Lacefield CO, *Bouchard MB, *Li W, Bruno RM, ‘SCAPE microscopy of the awake, behaving mouse brain’, SFN annual meeting, Chicago, 2015 (poster).

CA169) *Li W, *Voleti V, Schaffer ES, Mendes C, Mishra N, Mann RS, Hillman EMC, ‘Swept confocally aligned planar excitation (scape) microscopy for large-scale brain imaging in adult Drosophila melanogaster’, SFN annual meeting, Chicago, 2015 (poster).

CA170) *Ma Y, *Kim SH, *Shaik MA, Hillman EMC,‘The neural basis of resting state functional connectivity mapping resolved using simultaneous hemodynamic and wide-field GCaMP imaging’, SFN annual meeting, Chicago, 2015 (Dynamic poster).

CA171) *Voleti V, *Li W, Greaney M, Lacefield CO, Schoppik D, Bruno R, Hillman EMC, “SCAPE microscopy for high-speed volumetric functional imaging of the awake, behaving brain”, Optics and the Brain, OSA Biomed Congress, Fort Lauderdale FL, April 24-28th 2016 (Oral presentation).

CA172) *Li W, *Voleti V, Schaffer E, Vaadia R, Grueber RB, Mann RS, Hillman EMC, “SCAPE Microscopy for High Speed, 3D Whole-Brain Imaging in Drosophila Melanogaster”, Optics and the Brain, OSA Biomed Congress, Fort Lauderdale FL, April 24-28th 2016 (Oral presentation).

CA173) *Tsao A, *Galwaduge PT, *Kim SH, *Shaik MA, Hillman EMC, “Measuring the thermodynamic effects of neurovascular coupling in the awake, behaving mouse brain”, Optics and the Brain, OSA Biomed Congress, Fort Lauderdale FL, April 24-28th 2016 (Poster presentation).

CA174) *Galwaduge PT, *Yu H, *Patel KB, *Voleti V, *Shaik MA, Hillman EMC, “Towards Two-Photon Swept Confocally Aligned Planar Excitation Microscopy (2P-SCAPE)”, Optics and the Brain, OSA Biomed Congress, Fort Lauderdale FL, April 24-28th 2016 (Oral presentation).

CA175) *Patel KB, *Voleti V, Hillman EMC, “High-speed, 3D SCAPE Microscopy of Fresh Tissues for in situ Histopathology”, Translational Biophotonics, OSA Biomed Congress, Fort Lauderdale FL, April 24-28th 2016 (Oral presentation).

CA176) *Li W, *Voleti V, Schaffer ES, Mishra N, Hillman EMC, “Swept confocally aligned planar excitation (SCAPE) microscopy for the identification of neural circuits in adult Drosophila”, Society for Neuroscience Annual Meeting, San Diego CA, Nov 2016 (poster).

CA177) *Yu H, *Galwaduge PT, *Li W, *Voleti V, *Patel KP, Hillman EMC, "Towards two-photon SCAPE microscopy for extended depth, fast volumetric imaging of brain function", Society for Neuroscience Annual Meeting, San Diego CA, Nov 2016 (poster).

CA178) *Yang K, *Li W, Mann RS and Hillman EMC, “Super-Fly-gym: An open-source, closed-loop stimulation and behavior tracking system for whole brain imaging in adult Drosophila melanogaster”, Society for Neuroscience Annual Meeting, San Diego CA, Nov 2016 (poster).

CA179) Xu L, *Li W, *Voleti V, Hillman EMC, Firestein SJ, “Native olfactory sensory neuron imaging with swept confocally-aligned planar excitation (SCAPE) microscopy”, Society for Neuroscience Annual Meeting, San Diego CA, Nov 2016 (poster).


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CA180) *Ma Y, *Kim SH, *Shaik MA, *Zhao TH and Hillman EMC, "Widefield optical mapping of neural activity and cortical hemodynamics imaging during locomotion", Society for Neuroscience Annual Meeting, San Diego CA, Nov 2016 (poster).

CA181) *Zhao HT, *Chow D, *Kozberg MG, *Kim SH, *Shaik MA, *Saxena A, Dovas A and Hillman EMC, "Wide-field optical mapping (WFOM) of neural activity and hemodynamics in models of acute and longitudinal brain disease", Society for Neuroscience Annual Meeting, San Diego CA, Nov 2016 (dynamic poster).

CA182) *Kim S, *Ma Y, *Shaik MA, *Voleti V, Hillman EMC, "Comparison of wide-field optical mapping (WFOM) of neural activity and hemodynamics in awake mouse brain to resting state fMRI", Society for Neuroscience Annual Meeting, San Diego CA, Nov 2016 (poster).

CA183) *Shaik MA, *Kim SH, *Thibodeaux DN, Hillman EMC, “Endothelial dysfunction diminishes conducted vasodilation leading to abnormal functional hyperemia in the awake mouse cortex”, Society for Neuroscience Annual Meeting, San Diego CA, Nov 2016 (dynamic poster)

CA184) *Galwaduge PT, *Yu H, *Voleti V, *Patel K, *Li W, Hillman EMC “Single and two-photon swept confocally aligned planar excitation (SCAPE) microscopy for high-speed 3D imaging of neural activity”, SPIE Photonics West, 28th Jan 2017 (Oral presentation).

CA185) *Shaik MA, *Kim SH, *Ma Y, Hillman EMC, “Investigating the effect of nonselective COX-inhibition on neuronal and vascular dynamics in the awake mouse cortex”, Glial Biology: Functional Interactions Among Glia & Neurons: Gordon Research Conference, Ventura CA, March 2017 (Poster)

CA186) *Ma Y, *Thibodeaux DN, *Shaik MA, *Kim SH, Hillman EMC “Wide-field optical mapping of neural activity in awake mice and the importance of hemodynamic correction”, OSA Optics and the Brain, Optics in the Life Sciences Congress, San Diego, April 2017 (Oral presentation).

CA187) *Voleti V, *Li W, *Shaik MA, Wu M, *Campos CP, Wyart C, Hillman EMC,”Imaging the nervous system at different spatiotemporal scales with SCAPE microscopy”, OSA Optics and the Brain, Optics in the Life Sciences Congress, San Diego, April 2017 (Oral presentation).

CA188) *Yu H, *Galwaduge PT, *Voleti V, *Patel K, *Li W, *Shaik MA, Hillman EMC, “Two-photon Swept Confocally Aligned Planar Excitation Microscopy (2P-SCAPE)” OSA Optics and the Brain, Optics in the Life Sciences Congress, San Diego, April 2017 (upgraded to invited oral presentation)

CA189) Hillman EMC “A Second-generation SCAPE Microscopy System for High-speed 3D Imaging of Living Things”, Biomedical Optics Design and Applications, Optics in the Life Sciences Congress, San Diego, April 2017 (Invited presentation).

CA190) *Patel K, *Voleti V, *Zhao HT, *Campos CP, Hillman EMC “Developing SCAPE Microscopy for Real-time, 3D Cellular Imaging at the Point-of-Care” Biomedical Optics Design and Applications, Optics in the Life Sciences Congress, San Diego, April 2017 (invited presentation).

CA191) *Voleti V, *Li W, *Patel KB, *Shaik MA, *Perez-Campos C, Hillman EMC, “A Second-Generation SCAPE System for Fast, 3D Imaging of Neural Activity”. Society for


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General Physiologists annual meeting ‘The Optical Revolution in Physiology’, Woods Hole, Sept 2017.

CA192) *Shaik MA, *Thibodeaux SN, *Kim SH, Hillman EMC, “Wide-field optical mapping (WFOM) of large-scale neural activity and hemodynamics in the awake mouse cortex”. Society for General Physiologists annual meeting ‘The Optical Revolution in Physiology’, Woods Hole, Sept 2017. (Selected for ‘Poster-Blitz’ talk).

CA193) *Yu H, *Galwaduge PT, *Voleti V, Hillman EMC, “Optimizing the two-photon excitation for Swept Confocally Aligned Planar Excitation (SCAPE) Microscopy”, Society for General Physiologists annual meeting ‘The Optical Revolution in Physiology’, Woods Hole, Sept 2017.

CA194) *Li, W., *Mishra, N., Schaffer, E., *Voleti, V. and Hillman, EMC, “Swept Confocally Aligned Planar Excitation (SCAPE) Imaging for Whole Brain Circuit Identification in Adult Drosophila”, HHMI Janelia Conference ‘Emerging Tools for Acquisition and Interpretation of Whole-Brain Functional Data’, Nov 2017. (Selected as poster highlight talk)

CA195) *Kim SH, *Shaik MA, *Ma Y, *Zhao HT, *Thibodeaux DN, *Khabbazian M, Zheng T, Hillman EMC, “Spatiotemporal modeling of resting state neuronal activity in the awake mouse brain”, Society for Neuroscience Annual Meeting, Washington DC, Nov 2017 (poster).

CA196) *Mishra N, *Li W, Schaffer ES, *Voleti V, Hillman EMC, Axel R, “Spatiotemporal modeling of resting state neuronal activity in the awake mouse brain”, Society for Neuroscience Annual Meeting, Washington DC, Nov 2017 (dynamic poster).

CA197) *Xu L, *Li W, *Voleti W, Peterlin Z, Zhang C, Hillman EMC, Firestein S, “SCAPE microscopy reveals extensive antagonism in olfactory response to odor blends”, Society for Neuroscience Annual Meeting, Washington DC, Nov 2017 (poster).

CA198) *Yu H, *Benezra SE, *Galwaduge PT, *Voleti V, *Patel KB, *Li W, *Shaik MA, *Zhao TH, Bruno RM, Hillman EMC, ‘Combining Near-infrared Excitation with Swept Confocally-aligned Planar Excitation (SCAPE) Microscopy for Fast, Volumetric Imaging in Mouse Brain’, Optics and the Brain, OSA Biophotonics Congress, Fort Lauderdale, April 2018.

CA199) Hillman EMC, Schevon C, Costa R, Bandettini P, Zheng T, Jacobs J, Handwerker D, Smith E, Gonzalez-Castillo J, *Kim SH, *Ma Y, *Shaik MA, *Zhao HT, *Thibodeaux D, *Yu H, Khabbazian M, *Kim C, ‘Decoding the neural basis of resting-state functional connectivity mapping’, Annual BRAIN Investigator’s meeting, Bethesda MD, April 2018. (poster).

CA200) *Li W, *Voleti V, *Vaadia R, *Mishra N, *Xu L, Schaffer ES, Grueber W, Firestein S, Schoppik D, Hillman EMC, ‘Implementing and refining SCAPE for imaging small brains and neural populations’, Annual BRAIN Investigator’s meeting, Bethesda MD, April 2018. (student poster with travel stipend).

CA201) Hillman EMC, *Yu H, *Voleti V, *Li W, *Patel KB, *Perez-Campos C, *Lee GS, *Benezra SE, Lacefeld C, Bruno RM, Boyden E, Cosio D, Hosseini E, Celiker O, ‘SCAPE Microscopy - Technological Advances, New Applications and Dissemination’, Annual BRAIN Investigator’s meeting, Bethesda MD, April 2018. (poster).


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Service: Department, School, University

Departmental Committees and Duties (Biomedical Engineering)

2006-7 Co-chair of Biomedical Engineering Undergraduate Laboratory Committee. 2007-present Academic Advisor for Biomedical Engineering undergrad and graduate students. 2007-11 Chair of Biomedical Engineering Undergraduate Laboratory Committee. 2007-8 Responsible for Biomedical Engineering Faculty Meeting Minutes. 2007-9 Member of Biomedical Engineering Industrial Outreach and Internship

committee. 2007-present Member of Biomedical Engineering Communications and Outreach committee. 2007-9 Member of Biomedical Engineering BME Website and Multi-media committee.

Prepared and maintained majority of new departmental website content. 2007/9 Co-Organized Biomedical Engineering Holiday Party. 2009 Organized BME Alumni Day luncheon. 2011-12 Organizing and coordinating graduate seminar series 2012 Organized visit of NSF Director Dr Subra Suresh 2008-2014 Member of Biomedical Engineering Faculty Search Committee (Neural

Engineering). 2009-2015 Chair of Biomedical Engineering Industrial Outreach and Internship committee

and Career Service liaison. 2011-2016 Member of MRI Director search committee (BME / Radiology, 2013-2016) 2015 Member of BME IT sysadmin hiring committee 2015 Member of BME External Relations hiring committee 2013-present Member of Undergraduate committee 2016-present Member of BME Microscopy core advisory committee 2017-present Member of BME Entrepreneurship / Internship committee 2017-present Member of BME Publicity committee 2017-present Founder of BME Department faculty excellence committee

**Sabbatical: Spring 2015, **Maternity leave: Spring 2010, Fall 2012

Departmental Committees and Duties (Radiology / BME)

2011-2016 Member of Faculty Search Committee (Director of MRI Research)

Engineering School Committees and Duties

2008-2014 Executive Committee for Columbia University IGERT Fellows Program in Optical Techniques for Actuation, Sensing, and Imaging of Biological Systems (BioIGERT). Assistant Director for Instructional Programming.

2011- Gateway Lab Steering Committee, Columbia SEAS.

University Committees, Duties and Activities

2007-9 Invited Judge for the Columbia University Business School Entrepreneurial Greenhouse and Global Social Ventures business plan competitions.

2009-10 Co-Organizer of ‘Interdisciplinary Science Faculty Lunch Seminar Series’ with Ruben Gonzalez (Chemistry). Lecture series to promote and encourage interdisciplinary collaborations between Columbia Schools and Departments.


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2010- Office of the Executive Vice President for Research ‘Shared Facilities Committee’. Inter-school committee to evaluate campus-wide needs for shared facilities and equipment and to develop a strategy for funding and execution.

2011 HHMI post-doctoral fellow nominee selection committee. 2011- Search committee for the Executive Director of the new Mind Brain and Behavior

Initiative / Jerome L. Greene Science Center. 2011- EVPR Steering Committee for MBBI Imaging Center 2011- Member of Faculty Search Committee for Neurobiology and Behavior 2011-13 Irving Institute Imaging Pilot Award review committee. 2011- Harvey Karp Discovery Award in Neuroscience review and Steering Committee.

2012- Member, Executive Director Search Committee, Mind, Brain, Behavior Institute. 2012- Member, MRI Director Search Committee, Mind, Brain, Behavior Institute. 2013- Member of Department of Neuroscience search committee 2013- Member of Neuro-Z, combined MBBI / SEAS search committee 2015- Member, Z-MBBI Executive Committee 2016- Member of Z-MBBI Vivarium faculty advisory committee 2016- Member of Z-MBBI MR facility advisory committee 2017- Member of Z-MBBI Research Computing committee

Professional Services:

Scientific Advisory Boards

2016- Scientific Advisory Board. TranslaTUM, Technical University of Munich interdisciplinary center for translational cancer research.

2016- Founding Advisory Board, Current Opinion in Biomedical Engineering (Elsevier) 2017- NIH BRAIN Director Search Committee 2018- NIH “BRAIN 2.0” Working Group of the Advisory Committee to the NIH Director 2018- NIH BRAIN Neuroethics Sub-Group of the NIH ACD. Editorial Positions

2008 Special Issue Editor, OSA Applied Optics: “Topics in Biomedical Optics”. 2008-10 Associate Editor IEEE EMBS Conference Editorial Board, ‘Biomedical Imaging and

Image Processing”. 2008- Review Editor, Frontiers in Neuroenergetics Journal. 2009-10 Topical Editor, OSA Applied Optics: “Biomedical Optics” (In vivo microscopy,

spectroscopy, and neuro-Imaging). 2010 Feature Issue Editor, OSA Biomedical Optics Express: “Topics in Biomedical

Optics”. 2010-13 Associate Editor, OSA Biomedical Optics Express. 2011 Feature Issue Lead Editor, OSA Biomedical Optics Express: “ECI Advances in

Optics”. 2011 Invited Guest Editor for SPIE Journal of Biomedical Optics. 2012- Editorial Board Member, Journal of Biophotonics (Wiley). 2012- Editorial Board Member, Biomedical Spectroscopy and Imaging Journal (IOS Press) 2014-17 Associate Editor, Optica, OSA’s new high-impact pan-optics journal. 2014- Associate Editor, Neurophotonics, SPIE’s new journal on optics in the brain.


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2016- Founding Advisory Board Member, Current Opinion in Biomedical Engineering (Elsevier)

Service to Professional Societies

2008-12 Chair of the OSA Tissue Imaging and Spectroscopy Technical Group 2011 Optical Society of America (OSA) Biophotonics Award Steering Committee 2012-13 Member of inaugural OSA Michael S. Feld Biophotonics Award Selection Committee 2013 Chair, OSA Michael S. Feld Biophotonics Award Selection Committee 2013- OSA ‘Rising star’: assisting with publicity campaign to raise awareness of optics in

neuroscience. 2017- Member NIH BRAIN Initiative Director search committee. Conference Organization

2005-6 Program Committee Member for SPIE Optics East 2005 Optical Methods in Drug Discovery and Development conference

2006 Session Chair and Organizer for “Imaging Brain Function and Disease” at the Lasers in Medicine and Biology Gordon Research Conference 2006.

2006 Session Track Co-Chair, IEEE Engineering in Medicine and Biology Conference: “Diagnostic Instrumentation & Physiological Measurements”

2006 Session Chair and Organizing Committee Member for “Optics in Neuroscience” session at the. National Institute of Health Fifth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside conference.

2008 Program Chair for Optical Society of America BIOMED 2008 conference: “Methods for Diffuse Optical Imaging and Tomography”

2008 Associate Editor for IEEE Engineering in Medicine and Biology Conference 2008: “Biomedical Imaging and Image Processing”.

2008 Program Committee, 2008 IEEE Lasers and Electro-Optics Society (LEOS) 2008 Co-chair: "Advances in Optical Instrumentation", World Molecular Imaging Congress

(WMIC) 2008. 2008 Program Committee, 2009 SPIE/OSA European Conference on Biomedical Optics. 2009 Program Committee, ‘Neurons and Photons’ conference at the SPIE’s International

Symposium on Biomedical Optics 2009. 2009 Session Track Co-Chair, IEEE Engineering in Medicine and Biology Conference:

“Neural Engineering” 2009 Session Chair, "In vivo optical imaging of animal disease models", Engineering

Conferences International 2009. 2009 Session Chair (Brain) and Program Committee, 2009 ‘NIH Inter-Institute Workshop

on Optical Diagnostic and Biophotonic Methods from Bench to Bedside’ 2010 Program Chair for Optical Society of America BIOMED 2010 conference:

“Biological and Drug Discovery Imaging” 2010 Session Track Co-Chair, IEEE Engineering in Medicine and Biology Conference:

"Brain Functional Imaging" and mini-symposium organizer “Optical techniques for imaging and perturbing neural activity in vivo”.

2010 Track Co-Chair, IEEE Engineering in Medicine and Biology Conference: “Brain Functional Imaging” within Neural Engineering, Neuromuscular Systems, and Rehabilitation Engineering.

2010 Associate Editor for IEEE Engineering in Medicine and Biology Conference 2010: “Biomedical Imaging and Image Processing”.


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2010 Co-Chair, UK Royal Society Conference “Making light work: Illuminating the future of biomedical optics”

2011 Session Chair and organizer, BMES Conference Biomedical Optics Track (Novel Biomedical Imaging and Microscopy) and Neural Engineering Track (Neuroimaging).

2011 Session Chair and organizer, World Molecular Imaging Congress “Optical Methods” 2011 Organizing Chair for Engineering Conferences International “Advances in Optics

for Biotechnology, Medicine and Surgery XI” conference (with 2 co-chairs). 2011 Session Chair (Brain) and Program Committee, 2011 ‘NIH Inter-Institute Workshop

on Optical Diagnostic and Biophotonic Methods from Bench to Bedside’ 2012 Program Committee, SPIE 2013 “Optogenetics and hybrid-optical control of cells” 2012 Co-Chair Neurophotonics sub-conference at the OSA/SPIE European Conference on

Biomedical Optics (ECBO 2013). 2014 Program Chair, “Biophysics, Biology and Biophotonics: The Crossroads” at OSA

BIOMED 2014 2015 Co-Chair, “Neurophotonics” ECI “Advances in Optics for Biotechnology, Medicine

and Surgery XII” conference 2015 Co-Chair, “Neurophotonics” conference at SPIE / OSA ECBO meeting 2015 2015 Chair (founding), ‘Optics and the Brain’ conference at the OSA Optics in the Life

Science congress, Vancouver. 2016 Chair, ‘Optics and the Brain’ conference at the OSA Biomed congress, Ft

Lauderdale. 2016 Subcommittee Chair for ‘Optics in Biology and Medicine’ at the Centennial OSA

Frontiers in Optics (FIO) annual meeting, Rochester NY 2017 Chair, ‘Optics and the Brain’ conference at the OSA Biomed congress, San Diego. 2018 General Chair, OSA Biomed Congress 2018, (vice-chair 2016). 2018- Program Track Co-Chair, SPIE BiOS annual meeting Neurophotonics 2019 Co-organizer of NAE 2019 German-American Frontiers of Engineering Symposium

Grant Reviewer

2005 Grant Reviewer, North Carolina Biotechnology Center 2006 NIH Study Section Reviewer, ZEB1 OSR-A M1 S: ‘New Ways to Image Neural

Activity’ 2007 NIH Study Section reviewer: ZRG1 BST-M (50) R: ‘Nanotechnology’ 2007 NIH Study Section reviewer: BMIT: ‘Biomedical Imaging Technology’ 2008 NIH Study Section invitation: NCRR ‘Biotechnology Review Panel’ (declined) 2008 Grant Reviewer for the W. M. Keck Foundation. 2008 Grant Reviewer for Israel Science Foundation's Focal Initiatives in Research in

Science and Technology (ISF-FIRST) program 2008-9 Grant Reviewer for L'Agence Nationale de la Recherche, France. 2009 Grant Reviewer for Health Research Council of New Zealand. 2009 Region 1 Brain Peer Review Committee, the American Heart Association. 2009 NIH Study Section reviewer: SBMI: ‘Small Business Medical Imaging’ 2009 NIH Study Section invitation: SBMI: ‘Small Business Medical Imaging’ (June,

declined*) 2009 Grant Reviewer for Foundation for Polish Science MASTER program 2010 NIH Study Section invitation: NT: ’Neurotechnology’ (Jan, declined*)


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2010 NIH Study Section invitation: NIBIB ‘Team-Based Design in Biomedical Engineering Education’ (Nov, declined – scheduling conflict)

2010 Human Frontier Science Program (HFSP) 2010 NIH Study Section reviewer: NIBIB: ‘R13 Conference Grants Panel’ 2011 NIH Study Section invitation: EBIT: ‘Enabling Bioanalytical and Imaging

Technologies’ (June, declined – scheduling conflict) 2011 NIH NCRR P41 Site Visit x 2 2011 NIH Study Section invitation: SBIB: ‘Surgical Sciences, Biomedical Imaging, and

Bioengineering’ (Sept, declined – scheduling conflict) 2011 NIDA Cutting-Edge Basic Research Awards R21 panel 2011 NIH Study Section invitation: EBIT: ‘Enabling Bioanalytical and Imaging

Technologies’ (Oct, declined – scheduling conflict) 2012 CL1 Brain Peer Review Committee, the American Heart Association. 2012 NASA Smart Medical Systems and Technology review panel (SMST_2012) 2012 UK Medical Research Council (MRC) (twice) 2012 NIH Study Section invitation: EBIT: ‘Enabling Bioanalytical and Imaging

Technologies’ (Feb, declined – scheduling conflict) 2012 NIH Study Section invitation: MEDI: ‘Medical Imaging’ (June, declined*) 2012 NIH Study Section invitation: NANO: ‘Nanotechnology’ (June, declined*) 2012 NIH Study Section: NIBIB R25 Team-Based Education Review Panel (October) 2013 NSF: Ad-hoc reviewer (March) 2013 NIH NIBIB P41 Site visit (March). 2014 BRAIN initiative review panel ZMH-1 ERB C-09 ‘Planning for Next Generation

Human Brain Imaging’ (June) 2015 NIH NHLBI Intramural review panel (April) 2015 BRAIN initiative review panel ZMH-1 ERB C-09 ‘Planning for Next Generation

Human Brain Imaging’ (June) 2015 NIH SEP ZRG1 MDCN-N (92) ‘Glia Development, Function and Disease’ (July) 2016 NIH NST-1, F30 Predoctoral Fellowship (March) 2016 Chair, BRAIN initiative review panel ‘Technology Sharing and Propagation (R03)’

(June) 2017 NIH ZRG1 MDCN-E 03 CMBG and NOMD conflict panel (March) 2017 NIH ZRG1 SBIB-H(56) Early Phase Clinical Trials in Imaging and Image-Guided

Interventions (June) 2017 NIH BRAIN Initiative review panel ‘Standards to Define Experiments Related to the

BRAIN Initiative’ and ‘Data Archives for the BRAIN Initiative’ 2013-7 Charter Member NIH Study Section: MEDI: ‘Medical Imaging’ (June, Oct, Feb -) 2017 2018/05 ZRG1 MOSS-R (70) R Director's New Innovator Award DP2 (Dec) 2018 NIH BRAIN Initiative review panel ‘Theories, Models and Methods Review panel

ZEB1 OSR-F (A1)’ 2018 NIH BRAIN Initiative ‘Research Resource Grants for Technology Integration and

Dissemination (U24)’ ZNS1 SRB-M(06)

*declined due to pregnancy


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Manuscript Reviewer

Annals of Biomedical Engineering Applied Optics Biological Psychiatry Biomedical Optics Express Cell Cellular and Molecular Bioengineering Frontiers in Neuroenergetics IEEE Transactions on Medical Imaging Journal of Alzheimer's Disease Journal of Anatomy Journal of Biomedical Optics Journal of Cerebral Blood Flow and Metabolism Journal of Hepatology Journal of Neuroscience Journal of Nuclear Medicine Journal of Optics A Journal of the Optical Society of America A Journal of Physics D Medical Physics Nature Biotechnology Nature Medicine Nature Photonics Nature Methods Nature Neuroscience Nature Communications Nature Protocols Nanotechnology National Academy of Science / ILAR Journal NeuroImage Neuron Neuropsychiatric Disease and Treatment Optics Communications Optics Express Optics Letters Physics in Medicine and Biology Physical Review Letters PLoS One Proceedings of the National Academy of Sciences (PNAS) Review of Scientific Instruments Science Translational Medicine Science Advances Waves in Random and Complex Media


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Conference Abstract Review

2007 Conference abstract reviewer, Human Brain Mapping 2007. 2008 Conference abstract reviewer, IBSI 2008 (IEEE International Symposium on

Biomedical Imaging). 2009-11 Committee abstract reviewer: “Optical Instrumentation and Methods”, World

Molecular Imaging Congress (WMIC) 2009. 2010 Conference abstract reviewer, IBSI 2011 (IEEE International Symposium on

Biomedical Imaging). 2011 Abstract reviewer, OSA/SPIE European Conference on Biomedical Optics, ECBO 2011 Abstract reviewer, Brain 2011, Barcelona, Spain. 2013 Abstract reviewer, OSA/SPIE European Conference on Biomedical Optics, ECBO

Theses Supervised

Summary

Total Completed In Progress Doctoral As Supervisor: 20 9 11 As Reader: 22 22 3 Doctoral Theses, (Primary Supervisor, completed)

1) Sean A. Burgess Ph.D. Bioengineering BSc graduate, University of Washington Columbia University Graduate Student (BME) Master’s-to-PhD, (2006-2011) Dissertation: “Development and Applications of Laminar Optical Tomography for In Vivo Imaging” Current Position: Manager, Accenture (Management and Strategy Consultant) 2) Brenda Chen Ph.D. Bioengineering BSc graduate, Cornell University Columbia University Graduate Student (BME) Master’s-to-PhD (2007-2012) Dissertation: “Investigating mechanisms of hemodynamic control in the brain” Current Position: UX Design Engineer, Google NSF Graduate Fellowship 2009-12

3) Matthew Bouchard Physics undergraduate, Northeastern University Columbia University Graduate Student (BME) Master’s-to-PhD (2008-2013) Dissertation: “2D and 3D high-speed multispectral optical imaging systems for in-vivo biomedical research” Current Position: Analytics Services Director, Crossix Solutions. NDSEG graduate fellowship 2008-11, NSF Graduate Fellowship 2011-13

4) Lauren Grosberg Physics BSc graduate, Yale University Columbia University Graduate Student (BME) Master’s-to-PhD (2008-2013)


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Dissertation: “Development and applications of high speed and hyperspectral nonlinear microscopy” Current Position: Independent Research Engineer at SRI International. NSF Graduate Fellowship 2010-13, NINDS F32 Postdoctoral Fellowship 2014-

5) Cyrus Amoozegar Biomedical Engineering BSc graduate, Duke University Columbia University MD/PhD student (BME) (2008-2014) Dissertation: “Spatiotemporal Analysis of Functional Dynamic Imaging Data” Current Position: Equity Research Associate at Morgan Stanley 6) Mariel Kozberg Chemical-Biological Engineering BSc graduate, MIT, MA Columbia University MD/PhD student (Neuroscience) (2009- 2014) Dissertation: “The Development of Neurovascular Coupling in the Postnatal Brain” Current Position: Resident (Neurology), Harvard Medical School NINDS F31 fellowship 2013-2014 7) Pubudu Thilanka Galwaduge Physics BSc graduate, Drexel University, PA Columbia University Graduate Student (APAM) Master’s-to-PhD (2011-2017) Dissertation: “Optimization of two-photon excited fluorescence for volumetric imaging” Current Position: Electro-optical engineer, E-Ink Corporation 8) Mohammed Shaik Biomedical Engineering BSc graduate, Columbia University Columbia University MD/PhD student (2011-2018) Dissertation: “Evaluating endothelial function during neurovascular coupling in awake behaving mice using advanced imaging technologies” Current Position: Medical Student, CUMC NHLBI F30 fellowship 2015- 9) Ying Ma Biomedical Engineering BSc graduate, Zhejiang University, MS, Johns Hopkins University Columbia University Graduate Student (BME) PhD (2012-2018) Dissertation: “Analysis of resting-state neurovascular coupling and locomotion-associated neural dynamics using wide-field optical mapping” Current Position: Machine learning specialist

Postdoctoral Associates (past and current)

1) Baohong Yuan Ph.D. Biomedical Engineering PhD, University of Connecticut (Quing Zhu) Columbia University Post-Doctoral Research Scientist (Aug 2006 - Aug 2007) Current Position: Associate Professor of Biomedical Engineering, University of Texas at Arlington


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2) Clémence Bordier Physics PhD, Nanoscience Institute of Paris, Université Pierre et Marie Curie, (Claude Boccara) Columbia University Post-Doctoral Research Scientist (Mar 2008 - April 2010) Current Position: IQ System Engineer, GE Healthcare (France).

3) Barbara L’Heureux Physics and Neuroscience PhD, CNRS lab UMR8165 (IMNC), Orsay, France (Hirac Gurden) Columbia University Post-Doctoral Research Scientist (Dec 2009- Apr 2011) Current Position: World Wide Opportunities on Organic Farms

4) Timothy Muldoon Biomedical Engineering MD, PhD, Rice University / Baylor College of Medicine. Texas. (Rebecca Richards-Kortum) Columbia University Post-Doctoral Research Scientist (Jan 2011- July 2012) Current Position: Assistant Professor of Biomedical Engineering, University of Arkansas

5) Brenda Chen Biomedical Engineering PhD, Columbia University. (Hillman) Columbia University Post-Doctoral Research Scientist (June 2012- July 2013) Current Position: UX Designer at Google

6) Wenxuan Liang Biomedical Engineering PhD, Johns Hopkins University (2017) (Xingde Li). Columbia University Post-Doctoral Research Scientist (July 2018 - present)

7) József Mészáros Neuroscience PhD, Columbia University (2017) (David Sulzer and Christoph Kellendonk). Columbia University Post-Doctoral Research Scientist (June 2018 - present)

Co-advised Post-doctoral Fellows

6) Mohammad Khabbazian Electrical and Computer Engineering PhD, University of Wisconsin-Madison Columbia University Post-Doctoral Research Scientist (Jan 2016-June 2018) Co-advising with Prof Tian Zheng, Statistics, on dynamic analysis and unmixing of brain imaging data. 7) Sam Benezra Neuroscience PhD, New York University, (Michael Long)

Columbia University Post-Doctoral Research Scientist (Nov 2017-present) Co-advising with Prof Randy Bruno, Neuroscience, on the application of SCAPE for awake mouse brain imaging. 8) Shreya Saxena Electrical Engineering PhD, MIT, (Munther Dahleh)

Columbia University Post-Doctoral Research Scientist (Sept 2017-present) Co-advising with Prof Liam Paninski / Theory Center on dimensionality reduction, denoising and modeling of WFOM data.


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Current Research Group (PhD students who are in progress):

1) Venkatakaushik Voleti Biomedical Engineering BSc graduate, University of California, San Diego (UCSD) Columbia University Graduate Student (BME) Masters-to-PhD (2012-present) Approx thesis title: “Development and application of SCAPE microscopy” NSF IGERT Fellowship 2012-14

2) David Thibodeaux Biomedical Engineering BSc graduate, New Jersey Institute of Technology (NJIT) Columbia University Graduate Student (BME) Masters-to-PhD (2014-present)

3) Teresa (Hanzhi) Zhao Biomedical Engineering BSc graduate, Washington University, St Louis Columbia University Graduate Student (BME) Masters-to-PhD (2014-present)

4) Kripa Patel Biomedical Engineering BSc graduate, Boston University Columbia University Graduate Student (BME) Masters-to-PhD (2014-present) NSF GRFP 2016- // NSF IGERT Fellowship Spring 2015

5) Wenze Li Communication Engineering BS graduate, Beijing University, Electrical Engineering MS, Columbia University (2012) Columbia University Graduate Student (EE) PhD (2015-present) (formerly Aurel Lazar’s group) Approx thesis title: “Application of SCAPE microscopy to in-vivo Drosophila imaging”

6) Sharon Kim Biomedical Engineering BSc graduate, Johns Hopkins Columbia University Graduate Student (BME) MS-PhD (Sept 2011-present) Research Assistant in Hillman Lab 2013-2015. Joined BME PhD track in Sept 2015.

7) Hang Yu Biomedical Engineering MS graduate, Johns Hopkins Columbia University Graduate Student (BME) PhD track (Sept 2015-)

8) Richard (Wenwei) Yan Biomedical Engineering BS, Electrical Engineering MS graduate, Hong Kong University Columbia University Graduate Student (BME) PhD track (Sept 2018-)

9) Weihao Xu Biomedical Engineering BS, Beihang University Columbia University Graduate Student (BME) PhD track (Sept 2018-)

10) Hongkun Zhu Applied Physics / Mechanical Engineering BS, Sun Yat-Sen / Indiana Purdue, Biomedical Engineering MS, Johns Hopkins University. Columbia University Graduate Student (BME) PhD track (Sept 2018-)

11) Malte Caspar Medical Computer Science BS, Biomedical Engineering MS, University of Luebeck. Columbia University Graduate Student (BME) PhD track (Sept 2018-)


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Co-advising PhD students (in progress):

12) Rebecca Vaadia BS Biology, Wesleyan University (2013) Columbia University Ph.D. Student (Neurobiology and Behavior) (Sept 2014-) Co-advising with Dr Wesley Gruber NSF Fellowship (2016-)

13) Neeli Mishra BS Biomedical Engineering, California Institute of Technology (2014) Columbia University Ph.D. Student (Neurobiology and Behavior) (Sept 2014-) Co-advising with Dr Richard Axel

14) Lu Xu BS Medical Sciences, Peking Univ Health Science Center (2013) Columbia University Ph.D. Student (Biological Sciences) (Sept 2012-) Co-advising with Dr Stuart Firestein

Doctoral Theses, As Reader (On Thesis Committee):

1) Bradley Beattie “Improvements in the robustness and accuracy of bioluminescence tomographic reconstructions of distributed sources within small animals” Defense: December 2017 Adviser: Prof Andreas Hielscher (BME, Columbia)

2) Lu Meng “Spectral Filtering for Spatio-temporal Dynamics and Multivariate Forecasts” Defense: April 2016 Advisor: Prof Tian Zheng (Statistics, Columbia)

3) Auranuch Lorsakul “4D Mathematical Numerical Observer for Multi-dimensional PET Imaging” Defense: May 2015, Proposal: April 2014 Advisor: Prof Andrew Laine (Biomedical Engineering, Columbia).

4) Jordan Muraskin “Using neuroimaging to investigate the effect of expertise in rapid perceptual decision making” Defense: April 2015, Proposal: Oct 2014 Advisor: Prof Paul Sajda (Biomedical Engineering, Columbia).

5) Andrea Pisauro “Imaging hemodynamic activity in the mouse visual cortex” Defense: June 2014 Advisor: Prof Matteo Carandini (University College London). 6) Sarah Angelini “High Speed Videography on HBT-EP” (Columbia’s plasma physics Tokomak) Defense: May 2014 Advisor: Prof Mike Mauel (Applied Physics and Applied Math, Columbia).


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7) Ludguier Montejo “Computational Methods for the Diagnosis of Rheumatoid Arthritis with Diffuse Optical Tomography” Defense: October 2013 Advisor: Prof Andreas Hielscher (Biomedical Engineering, Columbia).

8) Jennifer Walz “Exposing Internal Attentional Brain States using Single-Trial EEG Analysis with Combined Imaging Modalities” Defense: Nov 2013, Proposal: June 2012 Advisor: Prof Paul Sajda (Biomedical Engineering, Columbia).

9) Evangelos Gatzogiannis “Functional Imaging Through Dark State Dynamics” Defense: November 2011 Advisor: Prof Wei Min (Chemistry, Columbia).

10) Ryan Field “Development of a high speed TCSPC imager” Defense: October 2013, Proposal: Oct 2011 Advisor: Prof Kenneth Shepard (Electrical Engineering, Columbia)

11) Stanley Huang “Single unit auditory nerve recordings in gerbil” Defense: June 2011, Proposal: Nov 2009 Advisor: Prof Elizabeth Olsen (Otolaryngology / Biomedical Engineering, Columbia).

12) Andrew Baik “Quasi-3D Multi-Channel Fluorescent Microscopy” Defense: October 2012, Proposal: May 2011 Advisor: Prof X. Ed Guo (Biomedical Engineering)

13) Na Lei “Microsystem Based on CMOS Multielectrode Array for Extracellular Neural Stimulation and Recording” Defense: March 2011 Advisor: Prof Kenneth Shepard (Electrical Engineering, Columbia)

14) Yuan He “Reconstructing Parameters of Electrocardiology Models from Boundary Potential Measurements”

Defense: Oct 2009 Advisor: Prof David Keyes (Applied Physics & Applied Mathematics, Columbia, Columbia).

15) Sarah Gallagher “Development of Trimethoprim-Based Chemical Tags for Live Cell Imaging” Defense: July 2009 Advisor: Prof Virginia Cornish (Chemistry, Columbia).

16) Ajna Borogovac “Mapping Cerebral Perfusion Using Arterial Spin Labeling MRI in Applications of Brain Pathology and Function”,


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Defense: July 2009, Proposal: May 2008 Advisor: Prof Andrew Laine (Radiology / Biomedical Engineering, Columbia)

17) Jonathan Cayce “Infrared neural stimulation in the brain” Defense: Jan 2013, Proposal: Feb 2009 Advisor: Prof Anita Mahadevan-Jansen (Biomedical Engineering, Vanderbilt University).

18) Xuejun Gu “Development of Transport-Theory-Based Reconstruction Algorithms for Optical Tomographic Imaging of Small-Tissue Volumes”, Defense: Feb 2009, Proposal: Mar 2008, Advisor: Prof Andreas Hielscher (Biomedical Engineering, Columbia)

19) Joseph Lasker “A Digital-Signal-Processor-Based Optical Tomographic System for Dynamic Imaging of Joint Diseases”, Defense: May 2008 Advisor: Prof Andreas Hielscher (Biomedical Engineering, Columbia)

20) David Schwartz “A CMOS Single-Photon Avalanche Diode Array for Fluorescence Lifetime Imaging and Microarray Applications”, Defense: May 2008, Advisor: Prof Kenneth Shepard (Electrical Engineering, Columbia)

21) James Masciotti “Small Animal Imaging and Instrumentation for Combined Optical Tomography and Magnetic Resonance Imaging”, Proposal: Feb 2008 Advisor: Prof Andreas Hielscher (Biomedical Engineering, Columbia)

22) Dae Kim “Four-Color DNA Sequencing on a Chip using Cleavable Fluorescent Reversible Terminator Nucleotides”, Defense: Nov 2007, Proposal: June 2007 Advisor: Prof Jingyue Ju (Chemical Engineering / Genome Center, Columbia).


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Undergraduates supervised for research

1) Nicole Lehrer Biomedical Engineering undergraduate, Tulane University MIT BioOptics Summer School (June – August 2005) Current Position: PhD student in Arizona State Media Arts and Sciences Program.

2) Matthew Bouchard Physics undergraduate, Northeastern University Northeastern University Co-operative work placement (July – Dec 2007) Research Technician Employee (Jan – June 2006) Northeastern University Co-operative work placement (Apr-Dec 2005) Current Position: Consultant, Campbell Alliance (Medical Devices)

3) Andrew Radosevich Biomedical Engineering undergraduate, Columbia University Undergraduate Researcher (April 2007-May 2009) Current Position: PhD student in Northwestern University Biomedical Engineering Program working with Prof Vadim Backman. 2011 recipient of an NSF Graduate Fellowship.

4) Roman Stolper Biomedical Engineering undergraduate, Columbia University Undergraduate Researcher (Sept 2007-May 2009) Current Position: After completing a Master’s in Computer Science at Cornell University, Roman was a Technical Analyst /VP at Goldman Sachs and is now a Senior Software Engineer at Major League Baseball Advanced Media.

5) Gary Walsh Electrical Engineering undergraduate, Columbia University Independent Study / Undergraduate Researcher (Sept 2007-May 2008) Current Position: PhD student in Boston University Electrical Engineering Program. 2009, DoD SMART fellowship awardee.

6) Praneeth Kocherlakota Biomedical Engineering undergraduate, Columbia University Undergraduate Researcher (Feb-Dec 2008) Current Position: Associate at Methuselah Advisors

7) Addason McCaslin Neuroscience undergraduate (senior / BSc graduate), Middlebury College Amgen Scholars Program Summer Student (June – Sept 2008) Full-time Research Associate (Feb 2009 – Sept 2010) Current Position: Neurology Resident, Stanford University (M.D. Northwestern 2014)

8) Elijah Li Biomedical Engineering undergraduate, Columbia University Undergraduate Researcher (Sept 2008-May 2009) Current Position: Clinical Account Specialist at Biosense Webster, Founder ShuoMii Life


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9) Rohit Swarnkar Computer Science undergraduate, Columbia University SURF Program Summer Student (June – Aug 2008) Current Position: Neurology Resident, SUNY Upstate

10) Ryan Sun APAM undergraduate, Columbia University (SEAS 2012) Undergraduate Researcher (March 2009-Sept 2010) Current Position: Harvard University Biostatistics PhD program.

11) Dmitry Timerman Biomedical Engineering undergraduate, Columbia University (SEAS 2012) Undergraduate Researcher (Dec 2009-Present) Current Position: Harvard University Medical School (HST Program) 2012-.

12) Joshua Figueroa Mechanical Engineering undergraduate, Columbia University (SEAS 2012) Undergraduate Researcher (Sept 2010-May 2011) Current Position: Natural Gas Trader at Con Edison

13) Ugne Klibaite Biomedical Engineering undergraduate, Columbia University (SEAS 2013) Undergraduate Researcher (Sept 2010-June 2012) Current Position: PhD Student, Princeton University, Computational Biology

14) Timothy Weber Biomedical Engineering undergraduate, Columbia University (SEAS 2014) Undergraduate Researcher (Sept 2011-2014) Current Position: MS-PhD Student, Boston University, Biomedical Engineering

15) Elsa Swanson Biomedical Engineering undergraduate, Columbia University (SEAS 2014) Amgen Scholars Program Summer Student (June 2012 - 2013) Current Position: Business Development Analyst at ACC Health Inc

16) Albert Zhou Biomedical Engineering undergraduate, Columbia University (SEAS 2015) Undergraduate Researcher (Nov 2011-2012, SURF Program Summer 2012)

17) Sandeep Palepu Engineering undergraduate, Columbia University (SEAS 2015) Columbia Undergraduate Scholars Program (March 2012 – July 2015) Current Position: Medical Student, Johns Hopkins University

18) Rohan Sawhney Biomedical Engineering undergraduate, Columbia University (SEAS 2014) Amgen Scholars Program Summer Student (June – Sept 2012)


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19) Tony Hung IEOR undergraduate, Columbia University (SEAS 2015) Work Exemption Program Summer Student (April 2013 – Sept 2013)

20) Katie Yang BME Undergraduate, Columbia University (SEAS 2017) Undergraduate researcher (May 2014-)

21) Robert Adelson BME Undergraduate, Columbia University (SEAS 2017) Undergraduate researcher (July 2014-2015)

22) Andrew Tsao BME Undergraduate, Columbia University (SEAS 2017) Undergraduate Researcher (April 2015-) (SURF)

23) Anikita Saxena (John Jay Scholar) Biophysics, Undergraduate, Columbia University (College 2018) Undergraduate Researcher (April 2015-2016) SURF

24) Thomas Bernhardt (CUSP) BME Undergraduate, Columbia University (SEAS 2018) Undergraduate Researcher (April 2015-) (CUSP program)

25) Charles Haohan Liang (Eggleston Scholar) APAM Undergraduate, Columbia University (SEAS 2018) Undergraduate Researcher (July-Sept 2015)

26) Mary-Kate Montgomery BME Undergraduate, Columbia University (SEAS 2017) Undergraduate Researcher (May 2016-)

27) John Mavroudes BME Undergraduate, Columbia University (3-2, SEAS 2017) Undergraduate Researcher (May 2016-)

28) Payal Rana BME Undergraduate, Columbia University (SEAS 2017) Undergraduate Researcher (May 2016-)

29) Srinidhi Bharadwaj BME Undergraduate, Columbia University (SEAS 2019) Undergraduate Researcher (Sept 2016-) (SURF, summer 2017)

30) Yi Zhang BME Undergraduate, South University of Science and Technology, China (2018) Visiting Researcher (Sept 2016-March 2017)

31) Alexis Willis Neuroscience Undergraduate, Carnegie Mellon University (2018) Visiting Student Researcher (May - August 2017)


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32) Sabrina Maliqi BME Undergraduate, Columbia University (SEAS 2018) Undergraduate Researcher (April 2017-)

33) Rony Moon SEAS Undergraduate (SEAS, 2020) Undergraduate Researcher (Sept 2017- )

34) Ericka Wu Columbia Undergraduate (College, 2021) Undergraduate Researcher (Dec 2017- )

Post-baccalaureates supervised for research (hired as staff)

1) Emily Pease Electrical Engineering BSc, Northeastern University Massachusetts General Hospital, Full Time Research Technician (Jan – June 2006) Current Position: Biomedical Sales Engineer at AD Instruments.

2) Matthew Bouchard Physics BSc, Northeastern University Massachusetts General Hospital, Part Time Research Technician Employee (Jan – June 2006) Current Position: Associate Consultant, Campbell Alliance (Medical Devices)

3) Addason McCaslin Neuroscience BSc, Middlebury College Amgen Scholars Program Summer Student (June – Sept 2008) Columbia University Full-time Research Associate (Feb 2009 – Sept 2010) Current Position: Neurology Resident, Stanford (MD Northwestern University 2014)

4) Shane Cheung Chemical and Pharmaceutical Science BSc, Dublin City University, Ireland Columbia University Full-time Research Associate (Feb-Sept 2011) Current Position: PhD student, University of Dublin

5) Aleksandr (Sasha) Rayshubskiy Computer Science BSc & MS, Cornell University IBM BlueGene Program (10 years) Columbia University Full-time Research Associate (Dec 2010- Present) Current Position: PhD student at Harvard University (Neuroscience) 2013-.

6) Evelyn Ramirez Psychology BSc, Hunter College Columbia University Full-time Research Associate (Aug 2011- July 2012) Current Position: PhD student, Clinical Neuropsychology, CUNY Queens College

7) Angela Liu Environmental Engineering BSc, Cornell University Columbia University pre-med / post-bac program (current) Casual Research Associate (Sept 2011- Present) Current Position: Research Assistant, Mt Sinai


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8) Citlali Perez-Campos MS Physics, Universidad Nacional Autonoma de Mexico Research Scientist and SCAPE Project Manager (June 2016-present)

10) Mary-Katherine Montgomery BS Biomedical Engineering, Columbia University Undergrad student researcher June 2016-May 2017 Research Scientist and Project Manager (May 2017-July 2018) Current Position: Image Analysis Senior Associate Scientist, Pfizer, San Diego

11) Carla Kim BS Philosophy and Neuroscience, Amherst College Lab Manager (Aug 2017-present)

12) Grace Sooyeon Lee, Columbia BME MS 2018 Biomedical Engineering BE, Yonsei University, Wonju, South Korea Research Scientist (Jan 2018-present) Masters Students supervised for research

1) Amir Iranmahboob Electrical Engineering BSc graduate, UC Berkeley Columbia University Graduate Student (BME) Master’s only (Sept 2006-Sept 2008) Current Position: Medical School Student, New York University in Sept 2008 -

2) Osuola Akinbiyi Computer Engineering Technology BSc graduate, DeVry University Columbia University Graduate Student (BME) Master’s only (Dec 2007-May 2009) Current Position: Senior Engineer at Fenwal, Inc. Medical technology company specializing in blood collection and processing.

3) Sarah De Leo Biological Engineering BSc graduate, Louisiana State Columbia University Graduate Student (BME) Master’s (Sept 2009-12) Current Position: Completed PhD thesis in Laboratory of Lance Kam. AAAS Science & Technology Policy Fellow at United States Department of Defense.

4) Sharon Kim Biomedical Engineering BSc graduate, Johns Hopkins Columbia University Graduate Student (BME) Master’s only (Sept 2011-13) Current Position: Research Assistant in Hillman Lab 2013-present. Joined BME PhD track in Sept 2015.

5) Tala Haddad Electrical Engineering BSc graduate, Princess Sumaya University for Technology, Jordan. Columbia University Graduate Student (BME) Master’s only – Fulbright Scholar (Jan 2012 – June 2012) Current Position: Special Projects Coordinator at King Hussein Cancer Foundation and Center


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6) Jacob Portes Physics and Philosophy BS, Stanford Columbia University Graduate Student (Physics and Philosophy) Master’s student (Sept 2013 – July 2016), including casual employment Current Position: Columbia University Neurobiology and Behavior PhD student, (Theory Center).

7) Leana Wang, Columbia BME MS 2017 Chemical and Biomolecular Engineering BS, NYU Poly Columbia University Graduate Student (BME) Master’s only (Sept 2015 – June 2016) Current Position: CUMC Clinical Research Coordinator.

8) Mariya Sergeyevna Sadakova Columbia EE MS 2018 Computer Science and Economics BA, Macalester College (2005) Columbia University Graduate Student (EE) Master’s only (Jan 2017 – Dec 2017)

8) Grace Sooyeon Lee, Columbia BME MS 2018 Biomedical Engineering BE, Yonsei University, Wonju, South Korea Columbia University Graduate Student (BME) Master’s only (March 2017 – Jan 2018)

9) Yannan Chen, Columbia BME MS 2018 Biomedical Engineering BE, Zhejiang University, China Columbia University Graduate Student (BME) Master’s only (Oct 2017 – present)

Medical Students, Residents and Visiting Scientists Mentored

1) Chad Ritch MD MD/MBA, University of Chicago IL Columbia University / NY Presbyterian Urology Resident. Mentored from 2008-11 to develop molecular imaging project for image guided surgical resection of prostate cancer. Current Position: Physician, Urologic Oncology, University of Miami FL

2) Thorsten Persigehl MD MD, University of Muenster Columbia University Research Fellow in Radiology. Mentored from June 2010-September 2011 to explore optical and MRI dynamic contrast techniques for quantitatively evaluating liver function. Current Position: Physician, Inst of Diagnostic and Interventional Radiology, University of Koln

3) Daniel Chow MD MD, University of California, Los Angeles (UCLA) Columbia University Radiology Resident. Mentoring since July 2011-2015. Under my guidance, Dan was accepted into the ‘RSNA Holman Pathway’ research track for Radiology Residents and will be working on imaging biomarkers of stroke using optical and MR imaging over the next 3 years. Won RSNA fellowship grant to support his work in my lab. Current Position: Physician and Assistant Professor of Radiology, UC Irvine. Co-Director of the UCI Center for Artificial Intelligence in Diagnostic Medicine.


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4) Teresa Wojtasiewicz BS Chemistry, Barnard College Columbia University Medical Student and Doris Duke Fellow in Neurosurgery. Since September 2011, I have been working with Teresa and Dr Guy McKhann to guide analysis of intraoperative optical brain imaging and electrophysiology data. Current Position: Physician, Neurosurgery, Johns Hopkins Hospital. 5) David Chung MD MD/PhD Columbia University Columbia University Neurology resident. Mentoring since August 2012-2015. Under my guidance, David applied for, and won an R25 fellowship to study the basis of vasospasm secondary to aneurismal subarachnoid hemorrhage, and to use in-vivo optical imaging and microscopy to understand the differential effects of drugs intended to treat these vasospasms. Current Position: Physician and researcher, Neurointensivist at Massachusetts General Hospital.

6) Prof Claure Lunardi Gomes and Anderson de Jesus Gomes Assistant Professors of Chemistry, University of Brasilia, Brazil Visiting Scholar: I sponsored Drs Lunardi and Gomes’s applications for an Inter-American Network of Academies of Science fellowship to fund a 1-2 month visit to my lab. Drs Lunardi and Gomes are experts in photochemistry and development of photoactivatible vasoactive compounds. They visited my lab in winter 2011/12, spent the summer of 2012 in the lab, and then returned for a year from Feb 2013-May 2014 under an additional fellowship.

7) Amy Xueqiong Bai MS Optoelectronics, Beijing Institute of Technology Visiting PhD student (under China Scholarship Council award) (Sept 2015-May 2016)

Honors and Awards won by Hillman Research Group

Undergraduate Andrew Tsao 2016 OSA Biomed Conference ‘Best Poster’ Prize

MD/PhD student Mohammed Shaik 2015 NIH/NHLBI F30 Fellowship, awarded on first application

MS-PhD student Kripa Patel 2015 Best Poster award and Travel Fellowship for ECI Advances in Optics for

Biotechnology, Medicine and Surgery 2015

2016 NSF Graduate Fellowship stipend and tuition

PhD student Ying Ma 2015 ISCBFM Travel Fellowship to attend Brain 2015 in Vancouver Radiology resident Daniel Chow MD 2012 Accepted to Holman Research Pathway, American Board of Radiology 2013 RSNA Resident Award Fellowship


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Neurology Resident David Chung MD, PhD 2013 R25 Research Fellowship

MD/PhD student Mariel Kozberg 2011 Amgen travel fellowship to Brain 2011 conference, Barcelona, Spain 2012 Joint winner at 7th annual MD/PhD symposium at Columbia. 2012 Student Attendance Fellowship for Gordon Conference on Brain Blood Flow and

Metabolism. 2013 NIH/NINDS F31 Fellowship, awarded on first application. 2013 Kavli Institute Travel Award to attend SfN meeting 2013. 2014 Travel award and Best overall poster and student presenter prize. ‘11th International

Conference on Brain Energy Metabolism “How Energy Metabolism Shapes Brain Function” conference, Denmark

2015 Titus Munson Coan Commencement Prize MS-to-PhD Student Sarah De Leo 2009 NSF Graduate Fellowship, 09/2009-09/2012 stipend and tuition.

"Development of an artificial independent and self-contained networking of neuronal cells in vitro with caged cyclic AMP".

(awarded just prior to joining my lab)

2009 NSF IGERT Fellowship (09/2009-09/2011) stipend and tuition As part of Columbia’s recently awarded ‘BioIGERT on Optical Techniques for Actuation, Sensing and Imaging of Biological Systems’.

2010 Accepted and funded to attend the 2010 NanoBiophotonics Summer School, at University of Illinois at Urbana-Champaign

2011 Oral presentation and travel fellowship to attend Brain 2011, Barcelona, Spain. (9% selectivity for oral presentations).

MS-to-PhD Student Lauren Grosberg 2009 NSF Graduate Fellowship, 09/2009-09/2012 stipend and tuition.

"Characterization of hyperspectral two-photon microscopy for 3D histology". (awarded during her 1st year in my lab)

2010 ‘Best Poster’ prize, OSA Biomed Conference, Miami, FL. 2010 Accepted to attended the 11th Annual Summer School on Adaptive Optics on

August 8-13, 2010 at UC Santa Cruz 2011 Invited talk, 30 min presentation at European Conference on Biomedical Optics,

Munich, 2011 2015 F32 Fellowship for post-doctoral research at Stanford University Department of

Neurosurgery.

MS-to-PhD Student Brenda Chen 2008 NSF Graduate Fellowship, 09/2008-09/2011 stipend and tuition.

"Neuro-Metabolic Modeling: Validation of the Astrocyte-Neuron Lactate Shuttle". (awarded during her 1st year in my lab):

2008 Travel Fellowship to attend and present a poster at the Gordon Research Conference on Brain Blood Flow and Metabolism.


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2010 NSF Travel and Attendance Fellowship to attend The 9th International Summer School on Biocomplexity from Gene to System, Istanbul, Turkey.

2010 Travel Fellowship ($500) to attend Society for General Physiologists meeting at Woods Hole, MA

2011 Invited Speaker at the US-Turkey Advanced Study Institute on Healthcare Challenges, Antalya Turkey

2012 PhD Thesis awarded with Distinction. MS-to-PhD Student Matthew Bouchard (Awards since I began mentoring him as an undergraduate co-op student in 2005): 2005 President’s Scholarship, Northeastern University. Full-tuition scholarship. 1 of 12

winners out of over 300 students 2006 Undergraduate Research Award, Northeastern University. $1,000 2006 Best Student Abstract Travel Award, OSA 2006 BIOMED Optics Conference 2006 CenSSIS Undergraduate Research Experiences Research Grant, Northeastern

University. $1,000 undergraduate research grant 2006 Educational Scholarship in Optical Science in Engineering, SPIE. $3,000

scholarship 2007 Barry M. Goldwater Scholarship and Excellence in Education Award. A $7,500

national scholarship 2007 William Jefferson Alcott, Jr. Award, Northeastern University. Award given to top

University-wide Co-operative education student, >2,000 students eligible 2007 Educational Scholarship in Optical Science in Engineering, SPIE. $3,000

scholarship 2008 NDSEG (ONR) Graduate Fellowship. 09/2008-09/2011 stipend and tuition. 2008 NSF Graduate Fellowship. 09/2011-09/2013 stipend and tuition.

"Characterization of active probes for dynamic imaging of electrical activity in vivo".

2010 Travel Fellowship ($500) to attend Society for General Physiologists meeting at Woods Hole

2013 “Spirit of Wallace H. Coulter” Award for graduate student innovation

Honors and Awards won by Hillman Undergraduate Student within Taught Classes

(total of $40,500 in prizes, stipends and grants):

2006-07 National Design Competition (RERC-AMI funded program run by Prof John Enderle at U of Connecticut, which

ran from 2003-2008 and provided $2,000 supplies budget for teams selected). 3 teams entered: “Accessible Power-Assist Hospital Bed Back Angle Controller”,

“Accessible Infusion Pump Interface” and “Accessible Home Vital Signs Monitoring System”. The latter team won 2nd place nationally ($750 prize).

2007 Global Social Ventures Competition (National Competition judged locally through Columbia Business School to

promote the development of socially conscious ventures that have both financial and social bottom lines. Student teams include MBA student or graduate). 1 team entered: A community weight tracker for health monitoring in developing countries.


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2007-08 National Design Competition 2 teams entered: “Accessible Weight Scale for Seated Users” and “Accessible Pill

Cap Dispensing/Cutting Device”. The latter team won 2nd place ($750 prize).

2007-08 BME IDEA Competition (NCIIA-run National competition for undergraduate and graduate student design

projects. $500 stipend is provided for teams winning entry to the first phase.Only one team can enter the second phase). 2 teams (out of 2) won $500 stipends and entry into the first phase. Projects: “An ACL injury rehabilitation system with Integrated Biofeedback” and “An ambulatory EKG and alert system for myocardial infarction monitoring”.

2008 Global Social Ventures Competition 1 team entered: Neonatal ventilator for use in developing countries.

2008-09 BME IDEA Competition 2 teams (out of 2) won $500 stipends and entry into the first phase. 1 team entered

the second phase. Projects: “IndyCool, a drug-refrigeration system for developing countries” and “SMArt: a motion-tracking system for evaluation of occupational therapy for children with Spinal Muscular Atrophy”.

2009-10 BME IDEA Competition 5 teams (out of 6) won $500 stipends and entry into the first phase. 1 team entered

the second phase. Projects: “SteadEase: A smart feedback device to reduce arm and hand tremors”, “Debridex: A novel surgical tool for steerable debriding”, ”Procar: A smart trocar for safe abdominal penetration in laparoscopic surgery”, “BornReady: Development of a respiratory support system for newborn infants in developing countries”, “Cervetics: An intelligent cervical dilator”.

2009-10 BMEStart Competition One of the Senior Design teams from my class (“Procar”) won second place in this

National NCIIA competition. The team beat 58 other student teams to win a $5,000 prize for their design of a smart trocar for abdominal laparoscopic surgery.

2010-11 BME IDEA Competition 2 teams won $500 stipends and entry into the first phase. Projects: ”Uzima” a

neonatal vital signs monitor for developing countries and “Free Flow”, a new approach to ventricular shunt design to reduce blockages.

2011 Rice University Global Health Technology Competition Team Uzima won first place in this competition, in which two team members

traveled to Rice University to compete with teams from universities around the country. Another team, Jaundicure also attended and reached the semi-finals level.

2011 NCIIA E-Team grant Team Uzima were awarded a 1 year for $18,500 NCIIA E-team grant to continue

development of their low-cost neonatal vital signs monitor. Graduating senior Gary Zhang visited Uganda with Prof Aaron Kyle in the summer of 2011 and has remained at Columbia after graduation to complete this work.


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Teaching

Assigned Teaching (as primary Lecturer)

Term Number Title Enrollment Rating Fall 2006 BMEN E3910 "Biomedical Engineering Senior Design" 51 2.59/5 Fall 2007 BMEN E3910 "Biomedical Engineering Senior Design" 44 4.59/5 Fall 2008 BMEN E3910 "Biomedical Engineering Senior Design" 54 4.03/5 Spr 2009 BMEN E6420 "Advanced Microscopy Fundamentals and Applications" 17 4.41/5 Spr 2009 BMEN E3810 "Signal Acquisition & Processing; EKG" (2 week module) 43 n/a Fall 2009 BMEN E3910 "Biomedical Engineering Senior Design" 44 4.02/5 Spr 2010 Maternity Leave Fall 2010 BMEN E3910 "Biomedical Engineering Senior Design" 32 4.08/5 Spr 2011 BMEN E6420 "Advanced Microscopy Fundamentals and Applications" 13 4.33/5 Fall 2011 BMEN E3910 "Biomedical Engineering Senior Design" 36 3.84/5 Fall 2011 ENGIE1112 "Freshman Engineering Gateway Lab – BME lab” 28 n/a Spr 2012 ENGIE1112 "Freshman Engineering Gateway Lab – BME lab" 14 n/a Spr 2012 BMEN E9700 “Graduate Seminar Series” 38 n/a Fall 2012 Maternity Leave Spr 2013 BMEN E6420 "Advanced Microscopy Fundamentals and Applications" 7 4.68/5 Fall 2013 ENGIE1102 "Freshman Engineering Gateway Lab – BME lab” 29 n/a Spr 2014 ENGIE1102 "Freshman Engineering Gateway Lab – BME lab” 11 n/a Fall 2014 ENGIE1102 "Freshman Engineering Gateway Lab – BME lab” 25 n/a Spr 2015 Sabbatical Fall 2015 ENGIE1102 "Freshman Engineering Gateway Lab – BME lab” 18 n/a Spr 2016 ENGIE1102 "Freshman Engineering Gateway Lab – BME lab” 12 4.72/5 Spr 2016 BMEN E3020 "Biomedical Engineering II” - Biomedical Imaging 48 4.53/5 Fall 2016 ENGIE1102 "Freshman Engineering Gateway Lab – BME lab” 24 Spr 2017 BMEN E3020 "Biomedical Engineering II” - Biomedical Imaging 44 Spr 2017 ENGIE1102 "Freshman Engineering Gateway Lab – BME lab” 16 Fall 2017 ENGIE1102 "Freshman Engineering Gateway Lab – BME lab” 22 Spr 2018 BMEN E3020 "Biomedical Engineering II” - Biomedical Imaging 50 Spr 2018 ENGIE1102 "Freshman Engineering Gateway Lab – BME lab” 28

n/a – instructor-specific evaluations are not available

BMEN 3910, Biomedical Engineering Senior Design: I substantially developed and revised this course during my 6 years teaching the 1st semester of this two-semester course. My efforts led to national recognition of many of our students’ projects. Taught 2006-2011, Co-taught with Dr Aaron Kyle in 2011.

BMEN 6420, Advanced Microscopy: Fundamentals and Applications: I proposed and developed this new graduate level course to attract interdisciplinary users and developers of advanced microscopy techniques. Enrollment was capped at 12 (enrollment down in 2013 owing to 4 overlapping bio-optics classes).


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BMEN E3810, Signal Acquisition & Processing; EKG Lab 1 module developed to teach sophomores about data acquisition, Matlab graphical user interfaces, Fourier analysis and electrocardiograms. Module content and material has been taught by lab sequence lecturer / teaching assistant every year since.

ENGIE1112, Freshman Engineering Gateway Lab (BME lab) After serving on the steering committee to redesign the freshman Gateway lab, I have developed and co-taught the Biomedical Engineering laboratory component of this class. During 2013-14 I have been the primary instructor of this lab course, for which I developed a module called ‘Body Heat’ which considers all aspects of medical devices and systems that involve heat and temperature. Students conceive of and prototype their own ‘Body Heat’ related device. In 2017, I redeveloped this class to focus on engineering solutions to the Opioid Crisis, based on my recent participation in the NIH Director’s Opioid workshop on the Development of Safe, Effective, and Non-Addictive Pain Treatments.

“I left each week thinking that this lab and course are what it really means to be an engineer, and a creative one at that” BMEN E3020. Introduction to Biomedical Engineering II (Imaging module) After a major curriculum change, all undergraduate BME students take a 2-part course to learn fundamental principles of diverse aspects of Biomedical Engineering. I developed and taught a 9-class module on Biomedical Imaging, covering MRI, X-ray, CT, Nuclear Imaging, Ultrasound and Optical imaging and microscopy, as well as fundamentals on image properties, interactions with matter, Fourier transforms for image formation, reconstruction and convolution and deconvolution.

“Professor Hillman is engaging and understanding, even though she did cover way too much material. She also seemed to care about us as people and not just want to cover what she wanted to cover.” “She is incredibly enthusiastic and passionate about what she teaches, and does so clearly, thoroughly, and with humor. It felt like she really wanted us to succeed, and was extremely flexible to meet the needs of her students.”

Invited Teaching

Spring 2005 Teaching seminar: Invasive and non-invasive optical brain imaging. Course: Biomedical Engineering Graduate Seminars. (Instructor, Irene Georgakoudi). Enrollment: (20) Department of Biomedical Engineering, Tufts University, Medford, MA.

Fall 2005 Teaching seminar: Functional Optical Imaging Course: Careers Options in Biomedical Research series. (Instructor, Bruce Rosen). Enrollment: (10) Massachusetts Institute of Technology (MIT), Boston MA.

Spring 2007 Invited Lesson: Spectroscopy and Microscopy in Biophotonics Course: BMEN 4898 Biophotonics (Instructor, Andreas Hielscher). Enrollment (10) Columbia University Department of Biomedical Engineering


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Summer 2007 Invited Tutor: Neurovascular Coupling in-vivo: From Single Neurons to BOLD Course: Multi-Modality Brain Imaging Short Course. Enrollment (30)

Massachusetts General Hospital / Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging.

Fall 2009 Lecture: In-vivo optical imaging and microscopy of neurovascular coupling Course: Neuroscience Bootcamp. Enrollment (25)

Columbia University Department of Neurobiology and Behavior.

Fall 2009 Lecture: In-vivo Functional Optical Imaging Course: BMEN E1001 Biomedical Engineering Pre-Professional Course (Instructor, Clark Hung). Enrollment (61)

Columbia University Department of Biomedical Engineering

Fall 2010 Lecture: In-vivo Functional Optical Imaging Course: BMEN E1001 Biomedical Engineering Pre-Professional Course (Instructor, Elisa Konofagou). Enrollment (72)


Spring 2011 Teaching session on Neurovascular Unit at Brain 2011, Barcelona, Spain. Course: “How to Study The Neurovascular Unit” Lecture (Hillman): “Imaging the Neurovascular Unit”

Spring 2011 Invited Lecture: In-vivo optical imaging and microscopy. Course: Chem G4137 Photonics and Spectroscopy (Instructor, Wei Min). Enrollment (18)

Columbia University Department of Chemistry

Fall 2011 Invited Lecture: Neurovascular coupling in health and disease. Course: G4100 Biology of Neurologic and Psychiatric Disorders (Instructors, Rene Hen, Scot Small and Stephen Rayport). Enrollment (20)

Columbia University Department of Neurobiology and Behavior.

Fall 2011 Lecture: Probing the neurovascular network using in-vivo optical imaging Course: Neuroscience Bootcamp, Enrollment (25) Columbia University Department of Neurobiology and Behavior.

Fall 2011 Lecture: In-vivo Functional Optical Imaging Course: BMEN E1001 Biomedical Engineering Pre-Professional Course (Instructor, Clark Hung). Enrollment (88)


July 2014 Lecture: ‘Methods for ultra-fast 3D volumetric microscopy in-vivo’ (plenary) Course: Montreal Light Microscopy Course (Instructor, Clare Brown, McGill University)

Fall 2014 Lecture: Two-photon microscopy and beyond Course: Seminar series for new neurobiology and behavior graduate students.

(Instructor, Darcy Kelley)

April 2015 Invited Course Instructor: Final Lecture (SCAPE Microscopy)


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Course: Cold Spring Harbor: “Quantitative Imaging: From Cells to Molecules (Instructor, Jennifer Waters, Harvard University)

August 2015 Invited Course Instructor: SCAPE Microscopy, Course: Cold Spring Harbor: “Imaging Structure and Function in the Nervous System” (Instructors, Michael Orger, Lucy Palmer, Jack Waters, Karen Zito)

Sept 2015 Invited Course Lecturer “Swept, Confocally-Aligned Planar Excitation (SCAPE) microscopy for fast in-vivo volumetric imaging”, (Horizon’s Lecture) Course: Wood's Hole: “Optical Microscopy and Imaging in the Biomedical Sciences (OMIBS)” (Instructors, Hari Schroff and Robert Hard)

April 2016 Invited Course Instructor: Two-photon microscopy and Light-Sheet microscopy Course: Cold Spring Harbor: “Quantitative Imaging: From Cells to Molecules

(Instructor, Jennifer Waters, Harvard University)

June 2016 Invited Course Instructor: Light-sheet and SCAPE Microscopy, Course: Neurophotonics Summer School, Laval University, Quebec (Instructors, Daniel Cote and Yves De Koninck, Laval University)

August 2016 Invited Course Instructor: SCAPE Microscopy, Course: Cold Spring Harbor: “Imaging Structure and Function in the Nervous System” (including 1-week onsite demo of SCAPE system) (Instructors, Michael Orger, Lucy Palmer, Jack Waters, Karen Zito)

August 2016 Invited Course Instructor: SCAPE Microscopy, Course: EMBO Light Sheet Course Dresden, Germany (Instructors, Pavel Tomancak, Emmanuel Reynaud, Jan Huisken)

March 2017 Lecture: Neurovascular coupling in health and disease Course: G4100 Biology and Neurology of Psychiatric Disorders.

(Instructor, Scott Small, Rene Hen, Steve Rayport)

August 2018 Invited Course Instructor: Light Sheet Microscopy, Course: Marine Biology Lab, Woods Hole: “Analytical and Quantitative Light Microscopy” (AQLM) (Instructors, Wendy Salmon, Jagesh Shah, Justin Taraska)

August 2018 Invited Course Instructor: SCAPE Microscopy, Course: Cold Spring Harbor: “Imaging Structure and Function in the Nervous System” (including 1-week onsite demo of SCAPE system) (Instructors, Michael Orger, Lucy Palmer, Jack Waters, Karen Zito)

August 2018 Invited Course Instructor: SCAPE Microscopy, Course: EMBO Light Sheet Course Dresden, Germany (Instructors, Pavel Tomancak, Emmanuel Reynaud)

August 2018 Invited Course Instructor: High-speed optical imaging and microscopy of in-vivo brain function, Course: BIGSS Biophotonics and Imaging Graduate Summer School (Instructor, Martin Leahy)


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Outreach

Public and Community Engagement

June 2007 ‘Back to School’ SEAS Alumni Lecture “The brain is just wires and plumbing": Engineering applied to the study of

neurovascular coupling and cerebral blood flow.” Presented my research in layman’s terms to visiting SEAS alumni.

June 2009 Middle School ‘Engineering 101’ lab “Fluorescence and Bioluminescence: Optics in Biomedical Engineering” Class taught to children of Columbia SEAS Alumni visiting the campus as part of the

2009 alumni events. Students learned about the difference between fluorescence and luminescence, and their relevance to biology. They then performed a lab experiment to explore UV fluorescence and chemi-luminescence.

Students: 20, ages ~12 – 16 years.

Sept 2009- Curriculum Enrichment Program at Samuel Gompers Career and Technical Education High School, Bronx NY As part of my NSF CAREER award I worked with my graduate student Lauren Grosberg proposed to establish an outreach program to expose high-school students in underserved communities to engineering design projects. The program ran from September 2009-May 2010 with additional support from the Columbia BioIGERT program. Classes were taught by graduate students from SEAS, who work in pairs to develop ‘Design Lab’ projects, that they then taught at Gompers high school in classes on Friday afternoons over 4 week sessions.

June 2010- Development of low-cost technologies for neonatal care in developing countries Building upon a series of developing country-focused senior design projects since Sept 2006, myself and Prof Aaron Kyle have recently established a more formal relationship with Mulago Hospital in Uganda to allow students in BME senior design class to develop low-cost and accessible technologies for neonatal care. For the past 2 years, with the help of Mulago and the Department of Pediatrics at Columbia University medical center, 7 groups seniors have worked on to develop design solutions and prototypes to address key biomedical problems in this setting. Our goal is to refine and ultimately manufacture and distribute the most promising of these devices in developing nations. In the summer of 2011, Dr Kyle and a graduating student took 3 of our prototypes to Uganda for field testing.

Oct 2011- Outreach Seminars for Columbia Mind Brain and Behaviour Initiative (MBBI) “Imaging the hungry brain”

Spoke to assembled alumni and donors at the Carlyle Hotel, NY to explain my research and promote interesting Columbia’s new MBBI program.

“In-vivo optical imaging and microscopy of brain function” Guidance for planning and architecture team for Columbia University Mind Brain and Behaviour initiative.

“Reading the mind: What can we measure?” Presentation at inauguration of The Grossman Center for the Statistics of Mind


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Oct 2011 Columbia SEAS ‘Family Day’ seminar “Applications of In-Vivo Microscopy and Biophotonics”

Engagement lecture to provide parents of new undergraduates with experience of research and teaching at Columbia.

March 2012 Science Expo Exhibit at the School at Columbia University “Peek-a-boo’ Taught children about medical imaging, focusing on cardiac and fetal ultrasound

(while 8 months pregnant!).

April 2012 Engineering Development Council members and Engineering Parents Council Event

“Imaging the Hungry Brain” Engagement lecture to assist with fundraising for Columbia Engineering School

March 2013 Columbia Trustees Briefing “Engineering and the Brain”

Spoke to the university’s trustees about the importance of engineering in neuroscience, interdisciplinary collaboration and my own recent research.

Oct 2013 Outreach Seminar for Columbia Mind Brain and Behaviour Initiative (MBBI) “Child's play?: Imaging early brain development.”

Spoke to assembled alumni and donors at the Carlyle Hotel, NY to explain my recent research and promote interesting Columbia’s new MBBI program.

Sept 2013 Columbia Women’s Engineering forum, “What is BME?” Lecture for female High School juniors visiting campus.

March 2014 Panel discussion on Gender Bias in Engineering Freshman ‘Art of Engineering’ Class Discussion on gender, racial and other bias in engineering and how to address it.

April 2014 Columbia CUSP CEAA Forum Keynote Speaker “I Wonder What My Brain is Doing Right Now" Speaker for Columbia scholars program ‘Wonder and Imagination’ lecture series.

May 2014 Columbia Personalized Medicine Workshop Speaker “Imaging Biomarkers”

June 2014 Columbia-Chile PUC Symposium Speaker Spoke to visiting scientists from Chile to promote collaboration between South America and Columbia-SEAS.

Sept 2014 Columbia SEAS Academic Assembly speaker Overview of my career path and my research field to incoming SEAS freshmen.

Oct 2014 Columbia Women’s Engineering forum, “What is BME?” Lecture for female High School juniors visiting campus.


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Nov 2014 SEAS 150th Anniversary Symposium Speaker “Frontiers in Brain Imaging”

Spoke drawing parallels between my work and that of Columbia alumnus Michael Pupin

Feb 2017 AAAS News Briefing panel: “Leading-Edge BRAIN Imaging Tools: Applications and Results

Panel organized by Jane Roskams to share the results of the BRAIN initiative at the annual AAAS meeting, Boston MA.

Nov 2017 Established and ran SEAS Opioid Design Challenge Organized 3 week ‘Hackathon’ style event bringing together students and faculty from across Columbia to learn about and devise solutions to the nation’s Opioid Crisis. We awarded $15,000 in seed funds to 10 teams with diverse solutions including social media solutions and medical devices.

March 2018 SEAS Parents Council Gave presentation on ‘New methods for high-speed imaging of brain activity’ followed by lab tour to Engineering School Parent’s council group.

April 2018 Zuckerman Institute, Brain Trust group Gave presentation on Tackling the undiscovered at the Zuckerman Institute, focusing on my methods for high-speed imaging of brain activity.

March 2018 Faculty Tech Talk “Engineering the Brain” Panel discussion event for students highlighting the importance of engineering and imaging in brain science and for detection and treatment of brain conditions.

April 2018 The BRAIN Fair: Celebrating 5 Years of Mapping the Future of Brain Health on Capitol Hill Kavli Foundation-led event at Capitol Hill to exhibit the work of the BRAIN initiative to congress and funding bodies.

June 2018 BRAIN initiative panel on “Mapping the Brain at the ‘Speed of Thought’ Panel discussion on BRAIN initiative discoveries in relation to therapeutics at the BIO International Convention, Boston MA.

Media: Popular Press Articles (selected)

1) “Getting up to Speed With Mirrors”, Biophotonics International ‘Technology Solutions’ article about my home-built two-photon microscope systems and their applications for brain imaging. May 2007 issue, Laurin Publishing Co Inc.

2) “Simple optical imager maps out internal organs”, Optics.org News Article about my recent paper in Nature Photonics. September 2007 issue.

3) “Dyes' biodynamic contrast highlights animal organs”, Biophotonics International ‘Research Highlights’ article about my recent paper in Nature Photonics. November 2007 issue, Laurin Publishing Co Inc.


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4) “Glow Mouse”, Columbia Magazine ‘Science, Medicine, Technology Research Highlights’ article about my recent paper in Nature Photonics. Fall 2007 issue.

5) “Unraveling Animal Anatomy”, Nature Photonics News and Views, S. Achilefu. Nature Photonics 1, 496 - 497 (2007).

6) “Imaging Animal Anatomy”, Nature Photonics Interview with Elizabeth M C Hillman. Nature Photonics, 1, 548 (2007).

7) “Top 10 innovations of 2010”, The small animal imaging product based on my DyCE technique, licensed to Cambridge Research and Instrumentation (CRi), was voted 6th in the Faculty of 1000 (F1000) Science Magazine’s Top 10 innovations of 2010.

8) “Interview with Elizabeth Hillman”, Featured in Semrock ‘Wavelength’ newsletter. http://www.semrock.com/elizabeth-hillman.aspx

9) SPIE online video interview “Elizabeth Hillman: In-vivo brain imaging” http://spie.org/x87062.xml

10) “View from... SPIE Photonics West 2012: Photons, neurons and wellbeing” Nature Photonics News and Views, article highlighting our presentation on multi-plane two photon microscopy for high speed 3D neuroimaging. Pile, D, Nature Photonics, 2012. 6(4): p. 222.

11) “Making sense of babies’ brains”, PNAS ‘First Look’ Blog article on our paper: Kozberg et al, PNAS 2013 paper on neonatal brain development. http://firstlook.pnas.org/making-sense-of-babies-brains/

12) “Shedding new light on infant brain development”, Columbia Engineering press release related to Kozberg et al, PNAS 2013 paper on neonatal brain development. Widely disseminated on the web.

13) “Baby versus adult brain, the fMRI picture”, Coffee Break Science Blog, another popular science article on Kozberg et al, PNAS, 2013.

14) “Multispectral system enables brain development discovery”, BioOptics World article on our PNAS paper. http://www.bioopticsworld.com/articles/print/volume-6/issue-2/departments/biooptics-breakthroughs/multispectral-system-enables-brain-development-discovery.html, March 1st 2013

15) “What secrets can functional MRI reveal about the developing infant brain?”, Imaging in Medicine, Invited Editorial, Elizabeth MC Hillman* & Mariel G Kozberg, June 2013, Vol. 5, No. 3, Pages 203-206 , DOI 10.2217/iim.13.29 http://www.futuremedicine.com/doi/abs/10.2217/iim.13.29?journalCode=iim

16) “Immature blood vessels may confound baby brain images”, SFARI (Simons Foundation Autism Research Initiative) Article by journalist Virginia Hughes on the importance of our results for the interpretation of brain imaging studies in infants and children. https://sfari.org/news-and-opinion/news/2013/immature-blood-vessels-may-confound-baby-brain-images

17) “The BRAIN Initiative: Opportunities for optics and photonics” BioOptics World Interview with Dr Hillman on the role that Optics might play in the goals of the BRAIN


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initiative. http://www.bioopticsworld.com/articles/print/volume-6/issue-5/features/neuroscience-biophotonics-the-brain-initiative-opportunities-for-optics-and-photonics.html, March 1st 2013.

18) “Experimental Tool Uses Light To Tweak The Living Brain” , National Public Radio (NPR). Dr Hillman was interviewed by Jon Hamilton at the OSA ‘Spatially Precise Optogenetics at Depth’ Incubator Meeting. Broadcast on December 26th 2013. http://www.npr.org/blogs/health/2013/12/26/256881128/experimental-tool-uses-light-to-tweak-the-living-brain

19) “SCAPE microscopy”, significant publicity related to our paper in Nature Photonics. Summary of press: http://www.nature.com/nphoton/journal/v9/n2/nphoton.2014.323/metrics

20) “Brain Week” Panel on NY-1. Panel discussion with 4 members, including Dr Hillman, on ‘Inside City Hall’ talking about engaging women and minorities in science and brain research. http://www.ny1.com/nyc/all-boroughs/inside-city-hall/2015/03/21/ny1-online---brainy--panel-offers-ways-to-make-neuroscience-fun.html

21) “Head Rush – Blood exerts a powerful influence on the Brain” Science News article summarizing the field of neurovascular coupling – worked with journalist Laura Sanders to advise on article. https://www.sciencenews.org/article/blood-exerts-powerful-influence-brain

22) “Neuroscience trailblazer wins BRAIN initiative grant for high speed microscopy”, BioOptics world mini-article on my BRAIN grant. http://www.bioopticsworld.com/articles/2015/12/neuroscience-trailblazer-wins-brain-initiative-grant-for-high-speed-microscopy-method.html?cmpid=EnlBOWDecember162015&eid=288593415&bid=1256660

23) “Elizabeth Hillman Wins BRAIN Initiative Grant for High Speed Microscopy Technique”, Report on my BRAIN initiative grant, http://www.microscopedia.com/News/Details/32993

24) “New view of brain development: Striking differences between adult and newborn mouse brain”, Press related to new paper in J Neurosci on brain development https://www.sciencedaily.com/releases/2016/06/160621193102.htm http://neurosciencenews.com/adult-newborn-brain-differences-4543/

25) “Young and old: fMRI and brain blood flow” http://www.spectroscopynow.com/details/ezine/15582b4026f/Young-and-old-fMRI-and-brain-blood-flow.html?tzcheck=1,1,1,1,1,1,1&&tzcheck=1, 1st July 2016

26) “Live Imaging Using Light-Sheet Microscopy”. The Scientist. Article including our work on SCAPE microscopy for imaging living organisms. http://www.the-scientist.com/?articles.view/articleNo/47280/title/Live-Imaging-Using-Light-Sheet-Microscopy/ 1st November 2016

27) “The real-time technicolour living brain” Technical Feature in Nature including our work on SCAPE microscopy. http://www.nature.com/nature/journal/v539/n7628/full/539315a.html?WT.feed_name=subjects_physical-sciences 9th November 2016.


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28) “Real-time 3D imaging of living organisms at sub-cellular resolution: Leica Microsystems to develop SCAPE microscopy”. Announcement of our exclusive license with Leica http://www.leica-microsystems.com/company/press-portal/press-details/article/real-time-3d-imaging-of-living-organisms-at-sub-cellular-resolution/News/detail/ 10th November 2016

29) “What your brain looks like when you 'zone out': Animation reveals the incredible amount of activity of our minds at rest”, Daily Mail write-up of our PNAS paper on resting state brain activity, http://www.dailymail.co.uk/sciencetech/article-4029204/What-brain-looks-like-zone-Animation-reveal-incredible-activity-minds-rest.html 15th December 2017.

30) “Watch a Resting Brain Light Up With Activity” WIRED Magazine write-up of our PNAS paper on resting-state brain activity. https://www.wired.com/2016/12/watch-brain-flicker-activity-rests/ 12th December 2017.

31) “New Imaging Techniques Unlock Secrets of the At-Work Brain at Work” BRAIN initiative AAAS panel 2017 write-up https://www.aaas.org/news/new-imaging-techniques-unlock-secrets-work-brain 16th February 2017

32) “Live-cell imaging: Deeper, faster, wider”, Article in Science Magazine mentioning SCAPE in the context of new imaging methods for live cell imaging. http://www.sciencemag.org/features/2018/03/live-cell-imaging-deeper-faster-wider 27th March 2018

Hillman CV Aug 2018 - Stanford UniversityD’Arceuil HE, Mandeville JB, Marota JJA, Rosen BR, Liu...

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