Highlights of the 2013 NCI Guidelines

Ira GoodmanAssociate Director for Administration

Organizational Capabilities

• Integration of education and training of biomedical researchers and health care professionals, including those from underserved populations, into programmatic research efforts

• Focus on cancer research problems in the catchment area

• Movement of findings through the translational pipeline via coordination with NCI and other peer-reviewed funding mechanisms

• Encouragement of collaborative links with other centers, institutions, industry

Transdisciplinary Collaboration and Coordination

Institutional Commitment

• Recognition of team science in promotion and tenure policies

Page Limitations

• Page Limits changed • From: ≤40 pages for Overview and 6 Essential Characteristics sections

To: a. Director’s Overview ≤ 12 ppb. Facilities ≤ 6 pp

c. Organizational Capabilities ≤ 12 ppd. Transdisciplinary Collaboration and Coordination ≤ 12

ppe. Cancer Focus ≤ 6 ppf. Institutional Commitment ≤ 12 pp = ≤ 60 pages total

• Research Programs from ≤ 25 pp to ≤ 12 pp• Shared Resources from ≤ 15 pp to ≤ 12 pp

Center Director

• Management and use of authorities and resources to advance the center’s research mission

Consortia

• Ongoing, tangible commitments from all consortium partners to the cancer center

• Requirement for each consortium partner to hold a portfolio of peer-reviewed cancer related grants

• Requirement that consortium operate as one cohesive center at time of application

Budget

• >$6,000,000 capped at current direct cost budget level • <$6,000,000 may request a direct cost budget of $1, 000,000 or 10%

increase, whichever is greater • The budget in subsequent years may receive cost-of living adjustments,

depending on the NCI policy in effect for the fiscal year

• Larger budget increases should be requested only under exceptional circumstances

• Funds may be budgeted for Program costs

Clinical Protocol and Data Management

• No longer a shared resource; now a central component of the CCSG and center

• Page limits reduced from 15 to 12, but add 5 pp for DSMB

Clinical Protocol and Data Management –DT 4

2008 2012Therapeutic Trial (THE) Treatment (TRE)Prevention Trial (PRE) Prevention (PRE)Supportive Care (SUP) Supportive Care (SUP)Screening (SCR) Screening (SCR)Early Detection (DET)Diagnostic (DIA) Diagnostic (DIA)Epidemiologic (EPI)Observational (OBS), or Outcome (OUT)Ancillary (ANC)Correlative (COR) Other (OTH)

Health Services Research (HSR)Basic Science (BAS)

Comprehensive Status Review

• Eliminated section on comprehensiveness • Eliminated 2 stage review process

Research Serving The Community

Added the requirement for comprehensive cancer centers to serve their catchment area as well as the broader population, through the cancer research they support.

Shared Resources

1. Shared Resources now to be grouped and scored together as basic, translational, clinical, population science, etc.

2. Eliminated usage tables for shared resources

Thank you