Healthcare Conference 2015

During our two-day, 2015 Stifel Healthcare Conference in New York City, attendees will have access to over 150 leading public (and private) biotechnology, healthcare services, healthcare facilities, major and specialty pharmaceuticals, medical devices, and senior housing companies. Each session is designed to get at the heart of the key issues that are driving industry and company fundamentals.

At Stifel, we have made it our goal to provide you with a conference that can be tailored to suit your needs. From interactive company presentations, panels, one-on-one meetings, and Stifel analyst-hosted company dinners; there will be many opportunities to interact with senior executives from presenting companies and healthcare industry leaders. The Stifel 2015 Healthcare Conference is designed to be rich in content and maximize your corporate leader interaction time.

NEW AND NOTEWORTHY FOR STIFEL’S 2015 HEALTHCARE CONFERENCE: More Time to Meet: • This year’s presentation sessions feature expanded time slots…now 40 minutes vs. 30 minutes in the past. The expanded meeting time will offer more opportunities for in-depth Q&A and discussion with presenting companies.

More Senior Leadership Presenters: • We expect over ninety percent of presenters to be CEOs and Presidents.

More Panels with Timely Topical Discussions: • The Stifel 2015 conference features expanded fireside chat “hot topic” panels…this year on both Tuesday and Wednesday, we will feature a “panel track” with 4-6 different doctor/industry discussions each day all hosted by the Stifel Research Healthcare Team. Pairing our research analysts with both prominent members of the academic community and executives from leading companies ensures you will gain an added depth of understanding to the important issues that are shaping the healthcare landscape. Showcased at our event will also be industry thought leaders who will challenge our perspectives and provide additional insight on healthcare and industry trends.

Stifel does and seeks to do business with companies covered in its research reports. As a result, investors should be aware that the firm may have a conflict of interest that could affect the objectivity of this report. Investors should consider this report as only a single factor in making their investment decision.

Please visit the Research Page at www.stifel.com for the research disclosures applicable to the covered companies discussed.

© 2015 Stifel. This report is produced for the use of Stifel customers and may not be reproduced, re-distributed or passed to any other person or published in whole or in part for any purpose without the prior consent of Stifel. Stifel, Nicolaus & Company, Incorporated, One South Street, Baltimore, MD 21202.

November17-18,2015•TheNewYorkPalaceHotel

Stifel, Nicolaus & Company, IncorporatedOne South Street, 15th Floor, Baltimore, MD 21202For more information, please contact us at StifelCorporateEvents@stifel.com.

StifelispleasedtoinviteyoutoourAnnualHealthcareConference,heldatTheNewYorkPalace Hotel, November 17-18, 2015. Please join us for informative sessions with many of the fastest growing and cutting edge healthcare companies from around the world.

CLICK HERE TO REGISTER

Abaxis, Inc. (ABAX)

Acorda Therapeutics, Inc. (ACOR)

Aerie Pharmaceuticals, Inc. (AERI)

Alcobra Ltd. (ADHD)

Aldeyra Therapeutics, Inc. (ALDX)

Align Technology, Inc. (ALGN)

Alliqua BioMedical, Inc. (ALQA)

Alnylam Pharmaceuticals, Inc. (ALNY)

Alzheon, Inc.*

AMN Healthcare Services, Inc. (AHS)

Applied Genetic Technologies Corporation (AGTC)

Apricus Biosciences, Inc. (APRI)

Aratana Therapeutics, Inc. (PETX)

Arbutus Biopharma Corporation (ABUS)

arGEN-X NV (ARGX)

Argos Therapeutics, Inc. (ARGS)

Array BioPharma Inc. (ARRY)

Ascendis Pharma A/S (ASND)

AtriCure, Inc. (ATRC)

Baxter International Inc. (BAX)

Becton, Dickinson and Company (BDX)

BIND Therapeutics, Inc. (BIND)

BioNano Genomics, Inc.*

BioSpecifics Technologies Corp. (BSTC)

Biota Pharmaceuticals, Inc. (BOTA)

Biotie Therapies Corp. (BITI)

Bonesupport AB*

Boston Scientific Corporation (BSX)

C.R. Bard, Inc. (BCR)

Cantel Medical Corp. (CMN)

Cara Therapeutics, Inc. (CARA)

Castlight Health, Inc. (CSLT)

Cempra, Inc. (CEMP)

ChemoCentryx, Inc. (CCXI)

Chiasma, Inc. (CHMA)

Chimerix, Inc. (CMRX)

CoLucid Pharmaceuticals, Inc. (CLCD)

Conatus Pharmaceuticals Inc. (CNAT)

Concert Pharmaceuticals, Inc. (CNCE)

Corindus Vascular Robotics, Inc. (CVRS)

CymaBay Therapeutics Inc. (CBAY)

Cynapsus Therapeutics Inc. (CYNA)

Cynosure, Inc. (CYNO)

Depomed, Inc. (DEPO)

Dicerna Pharmaceuticals, Inc. (DRNA)

Discovery Laboratories, Inc. (DSCO)

Durect Corporation (DRRX)

Eagle Pharmaceuticals, Inc. (EGRX)

Egalet Corporation (EGLT)

eHealth, Inc. (EHTH)

Endo International plc (ENDP)

EndoChoice Holdings, Inc. (GI)

Endologix, Inc. (ELGX)

EnGeneIC Ltd.*

Enlivex Therapeutics Ltd.*

Esperion Therapeutics, Inc.(ESPR)

Everyday Health, Inc. (EVDY)

Exelixis, Inc. (EXEL)

FibroGen, Inc. (FGEN)**

Flex Pharma, Inc. (FLKS)

Flexion Therapeutics, Inc. (FLXN)

G1 Therapeutics, Inc.*

Genocea Biosciences, Inc. (GNCA)

Geron Corporation (GERN)

GlycoMimetics, Inc. (GLYC)

GSI Group Inc. (GSIG)

Healthcare Services Group, Inc. (HCSG)

Healthways, Inc. (HWAY)

Henry Schein, Inc. (HSIC)

Horizon Pharma Plc (HZNP)

* Private companies** 1x1 meetings onlyAs of 11.13.15

Participating Companies

Healthcare Conference 2015

IDEXX Laboratories, Inc. (IDXX)

Innocoll AG (INNL)

Inogen, Inc. (INGN)

Inovio Pharmaceuticals, Inc. (INO)

Insmed Incorporated (INSM

Inspire Medical Systems, Inc.*

Intrexon Corporation (XON)

Intuitive Surgical, Inc. (ISRG)

Invuity, Inc. (IVTY)

Ion Beam Applications S.A. (IBAB.BR)

Isis Pharmaceuticals Inc. (ISIS)

Johnson & Johnson (JNJ)**

Keryx Biopharmaceuticals, Inc. (KERX)

Kite Pharma, Inc. (KITE)

Kolltan Pharmaceuticals, Inc.*

LeMaitre Vascular, Inc. (LMAT)

Lexicon Pharmaceuticals, Inc. (LXRX)

Lombard Medical, Inc. (EVAR)

Loxo Oncology, Inc. (LOXO)

MacroGenics, Inc. (MGNX)

Magellan Health, Inc. (MGLN)

Mainstay Medical International plc (MSTY.PA)

Marinus Pharmaceuticals, Inc. (MRNS)

MEDNAX, Inc. (MD)

Medtech S.A. (ROSA.PA)

MEI Pharma, Inc. (MEIP)

Misonix, Inc. (MSON)

Momenta Pharmaceuticals, Inc. (MNTA)

Navidea Biopharmaceuticals, Inc. (NAVB)

Neos Therapuetics, Inc. (NEOS)

Neovasc Inc. (NVCN)

NewLink Genetics Corporation (NLNK)

Nicox S.A. (Cox)

Nivalis Therapeutics, Inc. (NVLS)

Novadaq Technologies Inc. (NVDQ)

Novavax, Inc. (NVAX)

Ocera Therapeutics, Inc. (OCRX)

Ocular Therapeutix, Inc. (OCUL)

OncoGenex Pharmaceuticals, Inc. (OGXI)

Ophthotech Corporation (OPHT)

PerkinElmer, Inc. (PKI)

Pernix Therapeutics Holding Inc. (PTX)

PharmaMar, S.A. (PHM-MC)

Pharming Group N.V. (PHARM)

Progenics Pharmaceuticals, Inc. (PGNX)

Proteon Therapeutics, Inc. (PRTO)

PTC Therapeutics, Inc. (PTCT)

Quanterix Corporation*

Relypsa, Inc (RLYP)

Repligen Corporation (RGEN)

Rexahn Pharmaceuticals, Inc. (RNN)

Rockwell Medical, Inc. (RMTI)

Sage Therapeutics, Inc. (SAGE)

Spark Therapeutics, Inc. (ONCE)

Spectranetics Corporation (SPNC)

Strongbridge Biopharma plc (SBBP)

Supernus Pharmaceuticals, Inc. (SUPN)

Surgery Partners, Inc. (SGRY)

Symmetry Surgical Inc. (SSRG)

Syneron Medical Ltd. (ELOS)

T2 Biosystems, Inc. (TTOO)

Tandem Diabetes Care, Inc. (TNDM)

Teladoc, Inc. (TDOC)

Tetraphase Pharmaceuticals, Inc. (TTPH)

The Ensign Group, Inc. (ENSG)

TherapeuticsMD, Inc. (TXMD)

Theravance, Inc. (THRX)

Threshold Pharmaceuticals, Inc. (THLD)

Tokai Pharmaceuticals, Inc. (TKAI)

TRACON Pharmaceuticals, Inc. (TCON)

Participating Companies (continued)

* Private companies** 1x1 meetings onlyAs of 11.13.15

Healthcare Conference 2015

Participating Companies (continued)

* Private companies** 1x1 meetings onlyAs of 11.13.15

Healthcare Conference 2015

TransEnterix, Inc. (TRXC)

Triple-S Management Corporation (GTS)

Trovagene, Inc. (TROV)

Trupanion, Inc. (TRUP)

Ultragenyx Pharmaceutical Inc. (RARE)

Vascular Solutions, Inc. (VASC)

VCA Inc. (WOOF)

Viamet Pharmaceuticals, Inc.*

Vical Incorporated (VICL)

ViewRay, Inc. (VRAY)

Viking Therapeutics, Inc. (VKTX)

Vitae Pharmaceuticals, Inc. (VTAE)

vTv Therapeutics Inc. (VTVT)

Waters Corporation (WAT)

WellCare Health Plans, Inc. (WCG)

Xenon Pharmaceuticals Inc. (XENE)

ZELTIQ Aesthetics, Inc. (ZLTQ)

Zogenix, Inc. (ZGNX)

Zosano Pharma Corporation (ZSAN)

Zymeworks Inc.*

Healthcare Conference 2015

Hotel Information

7:30 am - 8:00 am

8:00 am - 12:30 pm

12:30 pm - 1:30 pm

1:30 pm - 5:00 pm

5:00 pm - 6:00 pm

7:30 am - 8:00 am

8:00 am - 12:30 pm

12:30 pm - 1:30 pm

1:30 pm - 5:00 pm

Tuesday, November 17

Continental Breakfast & Registration

Company Presentations and Industry Panels

Luncheon and Program

Company Presentations and Industry Panels

Cocktail Reception

Continental Breakfast & Registration

Company Presentations and Industry Panels

Luncheon and Program

Company Presentations and Industry Panels

Wednesday, November 18

Schedule

To reserve rooms at The New York Palace Hotel, please call the hotel directly at (800) 697-2522

and advise the reservations clerk that you are with the Stifel Healthcare Conference. Guest rooms

are $510.00 for single or double occupancy.

Each reservation must be guaranteed by a major credit card. All rooms not reserved in this manner

by Friday, October 16, 2015 will be released for general sale. Reservations made after October 16

will be handled on a space and rate availability basis only.

New York Palace Hotel

455 Madison Avenue

New York, NY 10022

(800) 697-2522