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Transcript of Health appraisal models in multiple sclerosis
HEALTH APPRAISAL MODELS IN MULTIPLE SCLEROSIS
GREG ROBERTS1* and ALEXA K. STUIFBERGEN2
1Department of Educational Psychology, The University of Texas at Austin, Austin, TX, U.S.A. and2School of Nursing, The University of Texas at Austin, Austin, TX, U.S.A.
AbstractÐThis study used multi-group path analysis to test the hypothesis that disability's total e�ecton self-rated health di�ers for di�erent-aged persons with multiple sclerosis (MS). Data (n= 806) col-lected as part of a larger study examining quality of life for persons with MS were used to constructand compare models of health appraisal for three age groups, 18 to 45 (n= 347), 46 to 60 (n= 339),and 61 to 78 (n= 120). The results suggest that while the same general model describes health appraisalin each age group, disability's total e�ect on self-rated health is less in the older and middle-agedgroups than in the youngest group. Further, disability's direct e�ect, rather than the hypothesized indir-ect e�ects, accounts for the group di�erences. The ®ndings support the other work in this areasuggesting that age may moderate the e�ect of ``objective'' health status on self-rated health. The gener-ally surprising ®nding was the ``break point'' for this e�ect Ð contrary to other research that suggestsolder persons may di�er from other-aged individuals, in this sample of persons with MS, the youngestgroup di�ered from the others. These results are discussed in terms of MS speci®cally and healthappraisal more generally. # 1998 Elsevier Science Ltd. All rights reserved
Key wordsÐchronic illness, multiple sclerosis, self-rated health, health appraisal, social comparison
INTRODUCTION
The way an individual appraises his or her health is
related to a number of important health outcomes,
including use of health care services (Weinberger et
al., 1986) and recovery from a major medical event
(Wilcox et al., 1996). Most notable, though, is the
relationship between health appraisal and sub-
sequent mortality. More than 15 large-scale studies
over the past 20 years suggest a robust relationship
between self-reported health level in older samples
and the mortality trend in that group, even when
other known and suspected correlates are controlled
(see Mossey, 1995).
While a causal role for self-rated health can not
be inferred from these ®ndings, the results do
suggest a need for greater understanding of the fac-
tors in¯uencing the appraisal process (Idler and
Kasl, 1991). Of particular interest is how the experi-
ence of chronic illness and disability may in¯uence
self-rated health status across the life span (Blaum
et al., 1994; Feinburg et al., 1985; Stewart et al.,
1989; Tarlov et al., 1989). Previous research has
focused almost exclusively on older samples, due,
largely, to the fact that chronic illness becomes
more common with age. The limited number of stu-
dies that have included middle-aged and younger
persons have used samples drawn from general
populations, and comparisons of individuals with
chronic illness across the life span have not been
possible.
There is some evidence that the factors a�ecting
the appraisal process may di�er across di�erent
chronic conditions, though very little research to
date has taken a disease-speci®c approach (Blaum
et al., 1994). The few chronic illnesses that have
been a target of investigations of this type have
relied on single-equation methods of analysis to iso-
late single variables or sets of variables that relate
in meaningful ways to health appraisal (Hays et al.,
1996; Johnson and Wolinsky, 1993). Only recently
have the analysis techniques necessary for integrat-
ing these discrete variables into comprehensive
models (i.e. multi-equation modeling) been applied
to health appraisal generally (Johnson and
Wolinsky, 1993), and there is virtually no research
of this sort addressing the e�ects of age and chroni-
city.
This study investigated the multi-factor structure
of health appraisal in a sample of persons with
Multiple Sclerosis (MS), a progressive, often debili-
tating illness of the central nervous system generally
diagnosed between 20 and 40 years of age. The pri-
mary question was whether age moderates the e�ect
of disability on perceived health for persons with
this disabling condition. Assuming such an e�ect, a
second purpose was to isolate the source(s) of age's
moderating role. Details on these purposes and a
discussion of the conceptual framework on which
Soc. Sci. Med. Vol. 47, No. 2, pp. 243±253, 1998# 1998 Elsevier Science Ltd. All rights reserved
Printed in Great Britain0277-9536/98 $19.00+0.00
PII: S0277-9536(98)00080-X
*Author for correspondence.
243
this study was based are in the next sections of thispaper.
Health appraisal, social comparison, and chronicity
One of the more enduring ®ndings of the researchon self-rated health is the lack of substantial corre-lation between an individual's self-rating and
``more-objective'' health measures (by clinicians,etc.). The considerable research that has consideredthis discrepancy suggests several key mediating vari-
ables, and these can generally be grouped as eitherphysical, psychological, or social in nature (Angeland Cleary, 1984; Idler and Angel, 1990). Withinthe ``physical domain'', actual physical health pre-
dominates. Though less implicated in the appraisalprocess than one might expect (thus the ``gap''described above), actual health status is nonetheless
an important factor in predicting self-ratings ofhealth (Rakowski and Cryan, 1990). Depression isprominent among the psychological factors a�ecting
health appraisal. Considerable evidence suggeststhat depressive symptoms may mediate the e�ect ofphysical health status on subjective health (seeMossey, 1995 for a review), and at least one study
suggests that depression may be directly associatedwith the comparison process that presumablyunderlies health appraisal (VanderZee et al., 1995),
a ®nding that may be more prominent for older in-dividuals when compared to the middle-aged(Levko� et al., 1987). Within the social domain,
economic status has been a consistent predictor ofself-rated health status. Better educated, employed,urban dwellers generally view health more optimisti-
cally than others when similar levels of disabilityare considered (Blaum et al., 1994; Liang, 1986;Wan, 1976).A second major ®nding characterizing this litera-
ture concerns the moderating e�ect of age on healthappraisal. Although older age is generally con-sidered to be a time of decline and failing health, a
number of early investigators found that elderly in-dividuals tend to be more optimistic in their healthevaluations than younger persons (Maddox and
Douglas, 1973; Murray et al., 1982; Stoller, 1984).Research comparing older persons to middle-agedsamples has been less conclusive (Cockerham et al.,1983; Levko� et al., 1987).
The apparent salience of ``age'' in this area ofresearch may be due to the social comparative pro-cess individuals often engage in when asked to
evaluate a personal attribute (Festinger, 1954; Sulsand Miller, 1977). In the case of self-evaluatedhealth, same-aged persons appear to be a prominent
reference group (Maddox, 1962), and older individ-uals may adjust their health expectations accord-ingly. Age may not be the only dimension along
which comparisons are made, however. Individualswith serious illness may use ``more ill'' others as acomparison group to insure favorable assessmentsof health (A�eck and Tennen, 1991; Suls et al.,
1991; Wood et al., 1985; VanderZee et al., 1995).
Indeed, the use of downward comparison (Wills,1981) to maintain positive appraisals of health,despite the presence of serious illness, appears to be
a widely-employed coping strategy and may havean e�ect on subjective health assessments indepen-dent of the e�ects of objective physical health and
self-reported psychological distress (VanderZee etal., 1995).
Much of the research on downward comparisonhas been done in controlled settings or in situationswhere participants have access to groups that make
such comparisons possible (cancer wards in hospi-tals is an example). Under such circumstances, the®ndings in favor of its use are considerable. When
chronically ill individuals are considered as mem-bers of their communities, however, social factors
that are not a consideration in more controlled set-tings may predominate, making downward com-parison less likely. For instance, in cases where one
of several salient groups has a numerical advantage,the more prevalent group is likely to be most instru-mental even if such means a less favorable compari-
son (Singer, 1981; Tornblom et al., 1993). For theperson with a chronic illness who is living in the
community, it's likely that the group of relativelyhealthy individuals will constitute the majority, ifnot the overwhelming majority, and, as a result, be
the key comparison group. A subset of similar-agedindividuals may also be selected from this largergroup for the reasons discussed previously.
A social comparative process may also shape thevariables thought to in¯uence levels of self-rated
health in individuals with chronic illness (i.e. social-economic and psychological factors). For instance,individuals may appraise their economic standing
based on the relative status (or perceived status) ofproximate, similar-aged persons (Sheeran et al.,1995). Because individuals with a chronic illness are
likely to be less fully employed (Minden et al.,1993) and more seriously in debt due to medical ex-penses (Minden et al., 1993), comparisons with non-
disabled and more ®nancially advantaged othersmay be less than productive (Sheeran et al., 1995).
Cognitive theories of depression also featuresocial comparison as a chief mechanism in under-standing depressive symptoms (e.g. Allbright et al.,
1993; DeVillis et al., 1990; Flett et al., 1987;Heidrich and Ry�, 1993; Swallow and Kuiper,
1990, Swallow and Kuiper, 1992, Swallow andKuiper, 1993; Weary and Edwards, 1994). Thiswork suggests that comparison with others operates
along a number of continua, including health status(Lewisohn et al., 1985) and economic status(Sheeran et al., 1995) and that an individual's level
of depression may stem partly from perceptions inthese respects.
Social comparison, then, may operate at pointsthroughout the appraisal process (physical, social-economic, psychological). The comparative process
G. Roberts and A. K. Stuifbergen244
may also di�er across the life span. Indeed, if agemoderates the relationship of disability and self-
rated health status, as has been suggested, agedi�erences may also be present in the social com-parative process thought to underlie this phenom-
enon.
Multiple sclerosis and self-rated health across the lifespan
A ®rst step in addressing the ``age-e�ects ques-tion'' is to assemble a general or baseline model of
health appraisal for persons with MS regardless ofage (Byrne, 1995). Figure 1 represents the startingpoint for this process. This model suggests thathealth appraisal in persons with MS is in¯uenced
largely by the same factors that operate in moregeneral populations (i.e. the psychological andsocial-economic domains suggested earlier).
Accordingly, direct e�ects are anticipated for thephysical aspects of health appraisal, as well as forthe social-economic and the psychological factors.
As suggested earlier, though the impact of physicalhealth factors (conceptualized here as disability dueto MS and comorbidity) is less than one might
expect, it nonetheless explains a considerableamount of the variance in self-rated health status.For persons with MS, health ratings are likely to beless optimistic than those of more-abled individuals.
This group is generally more disabled than the com-munity in general, and such is likely to be a salientfactor in the health appraisal process.
The direct e�ect for the social-economic factorre¯ects the considerable relationship between econ-
omic adequacy and actual health status (Campbell
et al., 1976). Persons in lower economic strata tend
have more health problems and less access to health
care, often resulting in lower actual health status as
well as lower self-rated health. Because MS-related
disability can reduce a family income by as much as
90% (Inman, 1984), the economic impact, in ``real
terms'', can be considerable, suggesting that this
group may be especially vulnerable. For persons
with MS, a second consideration in this respect is
the debilitating e�ect of the underlying comparative
process. As suggested earlier, persons with MS are
not likely to fare well when comparing the ade-
quacy of their resources to the resources of others
in their community, and the results of this compara-
tive process, based on a cognitivist view, may pre-
dispose this group to greater levels of depression,
and, presumably, lower self-ratings of health.
Social-economic factors, then, may a�ect self-
rated health status in two qualitatively distinct
ways. First, a direct e�ect may be evident due pri-
marily to the less adequate health and less available
care experienced by persons who are lower in this
respect. The indirect e�ect re¯ects the often disap-
pointing outcome of the comparative processes of
persons with MS in the economic sphere and the
increased levels of depression and decreased levels
of self-rated health that are likely to result.
A direct e�ect of depression on health appraisal
is also speci®ed. As indicated earlier, this relation-
ship has been well researched in general popu-
lations. Individuals who are depressed
psychologically tend to be less optimistic when eval-
uating a number of personal attributes, including
Fig. 1. Model of health appraisal for persons with MS.
Health appraisal models in MS 245
health status (VanderZee et al., 1995). Althoughseveral aspects of depression in persons with MS
are yet to be adequately sorted out (Boyle et al.,1991; MvIvor et al., 1984), the bivariate relationshipof depressive symptoms and self-rated health is
likely to be as evident in this group as in more gen-eral populations.Finally, age is also treated as a continuous, ex-
ogenous variable in Fig. 1. Although the primaryquestion posed by this study relates to the moderat-ing e�ects of age on the relationship of disability
and self-rated health, age's e�ect on the variables inFig. 1 may di�er at points across the life span. Thatis, the direct and indirect e�ects of age within di�er-ent age groups may vary across the cohorts. Thus,
the paths from age to the other variables in themodel are included.
Age-group di�erences in health appraisal for personswith MS
Figure 1 is a ``general'' model in that it representsthe health appraisal process across the life span forpersons with MS. However, if age moderates thee�ect of disability on self-rated health, as suggested,
this model may be more appropriate for some agegroups than for others. The presence of an age-e�ect may also suggest group di�erences in the
social comparative process that is (presumably) fun-damental to health appraisal. There are reasons tobelieve such di�erences may exist. The likely ``gap''
between the general group of persons with MS andtheir comparison group has already been discussed.The argument here is that the ``width'' of this gap
may di�er at points across the life span, dependingon the degree to which di�erent-aged groups withMS diverge from their respective comparisongroups. If one age group of persons with MS, for
example, is more similar (within a given domain) tosame-aged, proximate peers than a second agegroup with MS is to theirs, the comparisons of the
former group are likely to be more favorable.In the case of self-rated health, it has already
been pointed out that older individuals may enjoy
an advantage over younger persons with MS due tothe relatively more disabled nature of their same-aged peers. That is, older persons with MS are lessdissimilar, health-wise, from their comparison
group than are younger individuals with and with-out MS. What has been less fully addressed is thepossibility of age di�erences in the social compari-
sons associated with the other areas re¯ected inFig. 1 (i.e. social-economic and psychological).Several possibilities warrant mention.
Age group di�erences in disability's indirect e�ectthrough social-economic and psychological factors.Path 3 in Fig. 1 represents the indirect e�ect of dis-
ability through social-economic and psychologicalfactors. As suggested earlier, disability's e�ect inthis respect may be largely the result of the dis-couraging comparisons with same-aged, proximate
peers. Also, from a cognitivist view, the more dis-
couraging the results of such a comparison, the
greater the resulting level of depression and the
lower the level of self-rated health. Because middle-
aged persons with MS and their comparison group
are likely to be more economically dissimilar than
either older or younger individuals with MS and
their proximate same-aged peers (middle-aged per-
sons without MS are likely to be in their peak earn-
ing years), they may be more impacted by this
indirect e�ect of disability.
While the person with MS of any age may judge
himself or herself as ``lower'' in this respect (i.e.
economically) than his or her same-aged and more
healthy peer, and, accordingly, experience greater
levels of depression, the degree of such a discre-
pancy, and presumably the depth of the associated
depression, is likely to be less for the younger and
older groups than for the group of middle-aged in-
dividuals with MS. However, this may be the case
only when economic factors are considered in the
appraisal process. A di�erent pattern of age-di�er-
ences may be evident when disability's indirect
e�ect through depression alone (path 4 in Fig. 1) is
considered.
Age group di�erences in disability's indirect e�ect
through depression. Because MS is a progressive ill-
ness and disability is likely to worsen with age, one
would expect older individuals to be more disabled,
more depressed, and to report lower levels of self-
rated health. However, when a multi-equation
approach is taken, and speci®cally when the poten-
tially moderating e�ect of age is considered, the
assumptions suggested by a bivariate approach are
less tenable. The earlier-cited study by VanderZee
et al. (1995) suggests that increasing levels of dis-
ability may be associated directly with a need for
social comparison in the health domain (see also
Swallow and Kuiper, 1987; Swallow and Kuiper,
1990; Swallow and Kuiper, 1992). As an individual
becomes increasingly ill or disabled, he or she is
more likely to socially compare in an e�ort to man-
age and/or reduce levels of depression.
The VanderZee et al. (1995) study did not include
age as a variable, so it does not entirely address the
present discussion. However, if one considers that
disability due to MS increases with age, then older
persons with MS may be more likely to engage in a
social comparative process. Further, because older
individuals with MS appear to enjoy an advantage
in this respect for the reasons outlined earlier, the
results of their more frequent comparisons will be
more optimistic than the comparisons of other-aged
groups with MS. The moderating e�ect suggested
for age may be the result not only of the more
favorable conditions experienced by older folks, but
also the more frequent comparisons made by this
group.
G. Roberts and A. K. Stuifbergen246
Age group di�erences in the direct e�ect of disabil-ity. Finally, along with possible age-group di�er-
ences in the indirect e�ects of disability, groupdi�erences in its direct e�ect (path 1 in Fig. 1) mayalso be evident. Indeed, this path perhaps most
directly re¯ects the moderating e�ect of age thathas been discussed throughout this paper. In theabsence of the other e�ects that may mediate such
age di�erences, this relationship is essentially thebivariate correlation that has been described by anumber of researchers and serves as the bedrock of
much of the research in this area.
Research questions
In summary, two primary questions were
addressed by this study. First, ``Does age moderatedisability's e�ect on self-rated health status?'', and,second, ``Assuming such a moderator e�ect, at
what point(s) in the appraisal process do age di�er-ences emerge?''
METHOD
Sample
The data used in this study were collected as partof a larger study examining the impact of multiplesclerosis on quality of life (Stuifbergen, 1997).Participants were recruited through two Texas
chapters of the National Multiple Sclerosis Society.A total of 936 provided their name and address tothe investigators and indicated their willingness to
receive information about the study. Packets con-taining a questionnaire booklet, letter of infor-
mation (informed consent) and a postage paidreturn envelope were sent to all potential respon-dents. A reminder (postcard) was delivered to those
failing to return the survey within four weeks, anda second questionnaire was sent four weeks later incases where the postcard failed to produce a re-
sponse. A total of 834 questionnaires were returned(91%), of which 807 were usable, resulting in a ®nalresponse rate of 88%. From this total sample, the
806 participants between ages 18 and 78 wereselected for this study (mean of 48).Most participants were Anglo (93%) and female
(80%). The average length of diagnosis was
10.6 years. The average years of education was14.25, and 84% have at least a high school diploma(36% have a college degree or higher). Most
respondents were married (71%), and a total of 197(25%) reported living in a nonmetropolitan or ruralarea. About one-third (34%) reported being unem-
ployed due to their disability, while 30% wereworking full-time for pay. Sample characteristicsare summarized in Table 1. Population estimates on
these same variables for individuals with MS arealso included in this table (Minden et al., 1993).
Measures
Self-rated health. The four-item self-rated health(SRH) subindice of the Multilevel Assessment
Instrument (Lawton et al., 1982) was used tomeasure self-rated health. The four items compris-ing the SRH are items that have been widely used
elsewhere (Lawton et al., 1982), including the globalsubjective health item found on most health surveys(``How would you rate your overall health at thepresent time?''). The range of possible scores on the
SRH is four to 13. In the present sample, scoresranged from four to 13, and an alpha coe�cient of0.76 was obtained.
Functional disability due to MS. The incapacitystatus scale (Kurtzke, 1981) was used to measurethe level of disability due to MS. The incapacity
status scale (ISS) provides an objective measure ofthe degree to which an individual is unable to per-form his or her usual roles and activities. The ISShas been endorsed by an international group of
experts on MS. Evidence supporting its validity hasbeen presented by Kurtzke (1981).A single item from the ISS was used to measure
comorbidity: ``With regard to your physical healthÐ do you have any medical conditions (heart dis-ease, ulcers, diabetes) that require treatment: (0) no
signi®cant medical conditions (1) medical conditionsrequiring maintenance medication, but monitoringfrom physician is not required more often than
every 3 months (2) medical conditions requiring oc-casional monitoring by a physician or nurse, moreoften than every 3 months, but less often thanweekly (3) medical conditions requiring regular (at
Table 1. Comparison of study sample with characteristics of MSpopulation
Variable Study sample Population estimate
Age18±44 39% 35%45±60 46% 37%60±75 15% 23%75+ NA 5%
Gender 80% female 73% femaleDuration of Illness
Under 1 year 9% 12%1±5 years 25% 21%Over 5 years 66% 67%
Educational attainmentHigh school
graduate59% 60%
College graduate 36% 23%Employment status
In labor force 33% 29%Marital status
Married 74% 85%Separated 2% 2%Divorced 15% 4%Widowed 3% 4%Never married 6% 5%
EthnicityCaucasian 94% 94%African-American 4% 5%Hispanic 2% 1%
Self-rated health statusa
Excellent or good 50% 44%Fair or poor 50% 56%
aMeasured using the global-health item (``How would you rateyour overall health at the present time?'').
Health appraisal models in MS 247
least weekly) attention from a physician or nurse(4) medical conditions requiring daily attention by a
physician or nurse''. The sum of the remaining 15items were used as the measure of disability due toMS. The range of possible values on this modi®ed
scale was 0 to 60. In this sample, the total scoresranged from 0 to 48. An alpha coe�cient of 0.87was obtained.
Depressive symptomology. To measure levels ofdepressive symptomology, an abbreviated version ofthe Center for Epidemiological Studies Depression
Scale (Andersen et al., 1994) was used. Like thelonger edition, the ten-item version of the CESDuses a four-point scale ranging from zero (``none ofthe time'') to three (``most of the time''). Respon-
dents are asked to indicate how often in ``the pastweek'' they experienced each of the ten descriptionsof depressed mood (e.g. ``I was bothered by things
that usually don't bother me''). Andersen et al.(1994) report that the CESD-10 accurately predictsscores on the longer version of the scale, and it has
shown good test-retest reliability (Andersen et al.,1994). An alpha coe�cient of 0.86 was obtained forthis sample. The ten-item scale has a possible score
range of zero to 30, and the scores for the presentsample spanned this entire range.Perceived economic adequacy. The eight-item
Economic Adequacy Scale (Lobo, personal com-
munication, 1992) was used to assess the degree towhich participants felt their resources were ade-quate to meet their economic needs. Because this
self-report measure allows the respondent to deter-mine what ``adequate'' is, it re¯ects the social com-parative process that was described earlier as being
instrumental in this aspect of the health appraisalprocess for persons with MS. A sample item is``Does your family income allow you to meet yourdaily needs for living?'', to which participants are
asked to indicate ``not at all'', ``less than ade-quately'', ``adequately'', or ``more than adequately''.The possible range of scores is eight to 32. In this
sample, the scores ranged from eight to 32. Thealpha coe�cient was 0.94.
Analyses
The sample was divided into three groups. The``young'' group (n = 347) was aged 18 to 45.``Middle-aged'' individuals were 46±60 years of age
(n= 339), and the ``older'' group ranged from 61to 78 (n= 120). These categories re¯ect those used
by a number of the studies on self-rated health.Also, because age di�erences in social comparisonare thought to largely underlie health appraisal, the
age groups re¯ect stages in the life span tradition-ally associated with di�erences in these respects.Inter-correlations amongst the key variables were
computed for the total group. Means and standarddeviations for all of the measures in the study werecalculated for the three age groups. Analyses of var-
iance (ANOVA) were used, along with post-hoccomparisons, to determine if di�erences existedamong the observed means.The research questions were addressed using
multi-group structural equation modeling, followingprocedures described by Bollen (1989) and Byrne(1995). This approach involved comparing two
models at a time: one with the groups constrainedas equivalent on the parameters of interest and asecond, less restrictive model, in which these par-
ameters were free to take on any value (Byrne,1995). The competing models were tested using thedi�erence in their respective w2 values (Dw2). A sig-
ni®cant Dw2 indicated nonequivalence of groups,and provided a basis for evaluating the researchquestions addressed in this study. A ®rst step wasto ®t a general model of self-rated health to the
three age groups (Byrne, 1995). The modeldescribed in Fig. 1 was used as the starting pointfor this task. Path coe�cients and e�ect sizes were
estimated using LISREL 8.14 (Joreskog andSorbom, 1996).
Results
Intercorrelations of key variables are in Table 2.
A number of these coe�cients, when considered interms of their relative e�ects (Cohen, 1977), weremedium to large in size, ranging in value from
ÿ0.55 (disability and self-rated health) to ÿ0.31(comorbidity and self-rated health). Several rep-resented smaller-sized e�ects (Cohen, 1977), most
notably the correlation of age with depression(r=ÿ 0.11, p < 0.01), age with self-rated health(r=ÿ 0.09, p < 0.05), and age with comorbidity
(r= 0.14, p< 0.01).Table 3 includes the group means and standard
deviations for the instruments used in this study.
Table 2. Intercorrelations of key variables
Age CESD ECO SRH ISS Com
Age 1.0000CESD ÿ0.1135** 1.000ECO 0.0664 ÿ0.4125** 1.000SRH ÿ0.0869* ÿ0.4996** 0.2867** 1.0000ISS 0.2805* 0.3623** ÿ0.3319** ÿ0.5516** 1.0000Com 0.1372** 0.2005** ÿ0.1569** ÿ0.3052** 0.4300** 1.000
*p< 0.05; **p < 0.01.CESD = Depression; ECO = Economic adequacy; SRH = Self-rated health; ISS = Functional disability due to MS;
Com = Comorbidity level.
G. Roberts and A. K. Stuifbergen248
The three age groups di�ered signi®cantly from one
another in the level of disability due to MS
(F= 25.8, p< 0.01). Di�erences in levels of comor-
bidity were also present (F= 8.00, p< 0.01). While
the younger and middle-aged groups did not di�er
from one another, the older group reported a
greater prevalence of comorbid conditions. On the
CESD-10, the older group reported fewer depressive
symptoms than the younger (F= 4.40, p < 0.01),
while the middle-aged participants did not di�er
from the other two age groups in this respect.
There were marginal di�erences in the economic
adequacy of the three groups (F= 2.95, p < 0.05).
The older cohort indicated higher levels of ade-
quacy than the youngest group, while the middle-
age individuals did not di�er from the others. On
the self-rated health measure, there were no signi®-
cant di�erences between the age groups (2.60,
p = 0.07). This absence of a di�erence is in spite of
the signi®cantly higher levels of disability and
comorbidity in the older sample. It is evidence that
the ``age-e�ect'' observed in other samples may be
evident in a group of persons with MS, as well.
Further evidence of such was provided by the
comparison of the health appraisal models for the
di�erent groups. The proposed model of health
appraisal in Fig. 1 ®t the data well when run simul-
taneously within the three age groups (w2=7.68,
df = 12; n.s.; GFI = 0.96). The parameter esti-
mates (unstandardized) for this multi-group baseline
model are in Fig. 2. When analyzed in this way,
several age-group di�erences in the speci®ed paths
were suggested. For example, the middle-aged
group appears to di�er signi®cantly from the other
two in the e�ect of comorbidity on self-rated health.
While this path was not signi®cant for the middle-
aged cohort (b=ÿ 0.20), it was in the other two
groups (b=ÿ 0.298 and b=ÿ 0.364, respectively).
Table 3. Mean group di�erences on key variables
Variable Mean F p
young middle older
CESD 11.5a 10.5a,b 9.5b 4.40 <0.01ECO 2.9a 3.0a,b 3.1b 2.95 <0.05SRH 7.3 7.2 7.2 2.6 0.07ISS 15.2a 17.8b 22.6c 25.8 <0.01Com 0.77a 0.77a 1.02b 8.0 <0.01
Means with same letters in superscript do not signi®cantly di�er.CESD = Depression; ECO = Economic adequacy; SRH = Self-rated health; ISS = Functional disability due to MS;
Com = Comorbidity level.
Fig. 2. Group speci®c path coe�cients for baseline model. *zr1.96 (i.e. p< 0.05). NOTE: Coe�cientsare unstandardized. An estimate for each of the three groups is provided for each parameter; the ®rst
value represents the youngest group and the last value represents the oldest of the three groups.
Health appraisal models in MS 249
Similarly, the older and younger groups were simi-
lar in the e�ect of economic adequacy on self-ratedhealth (b =ÿ 0.158, n.s. and b =ÿ 0.167, n.s., re-spectively), while the middle-aged group appeared
to di�er signi®cantly (b= 0.391, p < 0.01).There also appears to be a downward linear
trend in the groups' coe�cient for both the direct
e�ect of disability on self-rated health (b =ÿ 0.104,b =ÿ 0.050, and b=ÿ 0.039, respectively) as well
as the total e�ect (b=ÿ 0.131, b=ÿ 0.083, andb =ÿ 0.056). To further explore this latter possi-bility, the total e�ect (all indirect and direct paths)
of disability due to MS on health appraisal wasconstrained to be equal across groups. This model(w2=37.5, df = 24, p= 0.03; GFI = 0.96) rep-
resents a signi®cantly less adequate ®t than themulti-group baseline model (Fig. 1). The Dw2 value
(Dw2=29.82, Ddf = 12, p < 0.01) suggests that thetotal e�ect of disability was not the same across thegroups, and serves as additional evidence that age
moderates the e�ect of disability on health apprai-sal for persons with MS (Byrne, 1995).To isolate the source or sources of these group
di�erences, and to answer the second research ques-tion, four models were run. The ®rst tested the
equivalence of the indirect path through economicadequacy along with the direct path from disabilityto health appraisal (paths 1 and 2 in Fig. 1). When
these were constrained equal across the groups, the®t was marginally acceptable (w2=31.2, df = 18,p = 0.03; GFI = 0.97), although when compared to
the baseline model, it was signi®cantly less adequate(Dw2=23.5, Ddf = 6, p< 0.01), suggesting that the
groups were not equivalent in this respect. Whenthe indirect path through depression along with thedirect e�ect of disability (paths 1 and 4) were con-
strained, a similar result was found. The model(w2=24.5, df = 18, p = 0.14; GFI = 0.98) was asigni®cantly less acceptable ®t than the baseline
model (Dw2=16.8, Ddf = 6; p< 0.01), suggestingagain the nonequivalence of the three groups.
The direct e�ect of disability as well as its indir-ect e�ect through economic adequacy and de-pression (paths 1 and 3 in Fig. 1) were also
considered. When these parameters were set equalacross groups, this model ®t the data reasonablywell (w2=27.7, df = 20, p = 0.12; GFI = 0.97),
although, as before, it represented a signi®cantlyless adequate ®t when compared to the multi-group
baseline model (Dw2=20.02, Ddf = 8, p < 0.01).Once again, this result suggests a signi®cant degreeof nonequivalence across the groups.
The ®nal model constrained only the direct path(path 1 in Fig. 1) from disability to health apprai-sal. This model also di�ered signi®cantly from the
baseline (Dw2=14.62, Ddf = 2, p< 0.01). Whenthis model was compared to the previous models
however, no di�erences were evident. The absenceof signi®cant Dw2 value indicates that the more con-strained models did not di�er signi®cantly from this
last model in their degree of ®t, suggesting that thesource of age-group di�erences in health appraisal
may be due only to disability's direct e�ect.Finally, because the source of group di�erences
in total e�ect of disability appeared to be due only
to di�erences in the direct e�ect (b=ÿ 0.104,b=ÿ 0.05, and b =ÿ 0.039), two additionalmodels were speci®ed and compared to the baseline
model to determine where the age groups di�eredfrom one another. When the young and middle-aged groups were constrained to have equal direct
e�ects, and the older group was allowed to freelyestimate on this parameter, the model (w2=18.85,df = 13, p = 0.13) di�ered signi®cantly from thebaseline (Dw2=11.17, Ddf = 1, p< 0.01) suggesting
that these two groups di�ered signi®cantly in theirdirect e�ect on self-rated health. When middle-agedand older individuals were constrained to have
equal coe�cients for the direct e�ect (w2=8.11,df = 13, p= 0.84), there was no di�erence in w2
values (Dw2=0.43, Ddf = 1, p>0.05). Thus, the pri-
mary di�erence in groups was in disability's directe�ect for the younger group when compared to themiddle-aged and older samples.
DISCUSSION
Considerable literature in recent years suggeststhat di�erent-aged individuals rate health in di�er-ent ways. Little of this research, however, has
focused on middle-aged and younger samples, andvirtually none of it comes from a disease-speci®cperspective. The life span model of health appraisal
developed and tested in this study suggests that thedi�erence in the direct e�ect of disability dis-tinguishes the health-appraisal models of di�erent-aged individuals with the chronic, disabling con-
dition of MS. Like members of other groups, olderpersons with MS appear to have an advantage inthis respect over younger individuals with this ill-
ness. Even though more disabled, these older per-sons appear to ``protect'' their self-perceptions ofhealth by relying less on their level of disability
when making a health appraisal.Further, it appears that this di�erence is due pri-
marily to disability's direct e�ect, rather than itsvarious indirect e�ects on self-rated health. This
suggests the health appraisal processes of di�erent-aged persons with MS di�er primarily in the e�ectthat illness- and disability-related variables have on
self-rated health. While economic and psychologicalfactors are clearly implicated in the health apprai-sals of all three age-groups, the age groups do not
di�er in the degree to which these two factors facili-tate disability's e�ect. This also suggests that thesocial comparison process, as it relates to health
appraisal, may di�er primarily along a health-re-lated dimension.What is unexpected is the absence of a signi®cant
di�erence between middle-aged and older individ-
G. Roberts and A. K. Stuifbergen250
uals, in this respect. The reasons for this are notclear, although one possibility relates to the di�cul-
ties associated with the early stages of diagnosis.The pervasive emotional e�ect of coping with MSearly on may make it a more salient issue in the
appraisal process, even though there may be littleevident disability. Perhaps, only after an individualhas the opportunity to adjust and develop some
coping strategies does he or she become less in¯u-enced by disability status when making healthappraisals. This topic warrants additional study.
Another possibility for further research suggestedby this study concerns age's within-groups-e�ect ondepression. The ®ndings suggest the younger groupof persons with MS may become less depressed as
they move towards middle-age, while middle-agedand older individuals experience little change in thisrespect. This is consistent with much of the litera-
ture addressing depression and MS, and it alsohighlights the importance of separating the respect-ive e�ects of age, disability level, and length of
diagnosis on depression and self-rated health. Morework on these interrelationships in this populationis needed.
Limitations
Several comments concerning the study's design
are necessary. First, while the sample generallyre¯ects the population of persons with MS on mostkey variables, participants were solicited usingmembership rosters of MS societies, making it poss-
ible that the sample overrepresents people with amore active and concerned approach to their dis-ease. Also, because MS is less prevalent in more
temperate climates, the comparison process thatpresumably underlies health appraisal may operatedi�erently in southwestern parts of the U.S. when
compared to regions where greater numbers of indi-viduals with MS reside.There are also some problems associated with the
measurement of disability (Blaum et al., 1994; Idler,1993). There is little consensus on the best way tomeasure this variable and it seems reasonable thatdi�erent settings and perhaps di�erent types of dis-
ability will require di�erent approaches (Idler,1993). The disease-speci®city and extensive use ofthe ISS made it a reasonable choice in this case.
Finally, because cohort e�ects may play a role indi�erent levels of subjective health for di�erent agegroups, cross-sectional data, as this is, may not ade-
quately capture the phenomenon (see Idler, 1993for a discussion of this issue).
Implications
There is a need for more knowledge on the healthappraisals of persons with lifelong chronic con-
ditions. The apparent relationship of self-ratedhealth and mortality patterns suggests that knowl-edge about the former may provide insights aboutthe latter. This may be especially important for a
group like the one studied here. Individuals withchronic physical illness with no known cure and lit-
tle available treatment may bene®t from interven-tions that are aimed at more psychosocial aspectsof the disease. While disability's direct e�ect on
self-rated health may be relatively di�cult to in¯u-ence, health-care providers and others may havemore success in addressing disability's indirect
e�ects. For instance, depression and the social com-parative process it implies are powerful mediatorsof disability's e�ect, regardless of age. By aiming
interventions in this direction, the individual withMS may experience improved levels of psychologi-cal functioning, resulting in increased perceptions ofhealth.
A focus on the indirect e�ects of disability mayalso may help to minimize the disability experiencedby an individual, or at least his or her ``perception''
of the disability. While the course of this illness ispresently beyond control, the way a person withMS responds to his or her illness is not. By increas-
ing the availability of psychological copingresources, the individual with MS may be less likelyto play the social role of ``sick person'' and, as a
result, experience less disability (Brooks andMatson, 1990; Hyman, 1975).Increasing resources in other respects may also be
important. The indirect e�ect of disability through
economic factors (alone as well as through de-pression) suggests that perceived and real inadequa-cies in this respect may minimize levels of self-rated
health. Support, ®nancial and otherwise, may be animportant factor in helping persons with MS ratetheir health more favorably, and, quite possibly, ex-
perience less severe levels of disability.
AcknowledgementsÐThis research was supported by grantR29NRO3195-03S1, National Institute of NursingResearch, National Institutes of Health andR29NRO3195-03S1, O�ce of Research on Women'sHealth, O�ce of the Director, National Institutes ofHealth. The authors would like to thank Da'LynnClayton, Ida Miller, and Sharon Rogers for their helpwith data collection and Dr. Heather Becker for her help-ful comments on an earlier version of this paper.
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