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FEDERATION OFinfection societies

CONFERENCE 2018www.fis2018.co.uk

13 - 15 November 2018Sage Gateshead - Newcastle

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POSTER LIST

CLINICAL CASE REPORTS001 Case report of NDM–producing Klebsiella pneumoniae complex upper urinary tract infection

treated with ceftazidime-avibactam and aztreonam combination therapyRobert Shorten1, Frances Garraghan2, Phillipa Burns1, Iain McIntyre2, Kirsty Dodgson2, Louise Sweeney2

1Public Health England, Manchester. 2Manchester University Foundation Trust

002 An unusual case of meningitis – thirsty for the diagnosisFiona McGill1,2,3, Jon Folb1, Gareth Roberts1, Paul Roberts1, Caroline Corless1, Nick J Beeching4,2

1Liverpool Clinical Laboratories, Royal Liverpool University Hospital. 2Tropical and Infectious Diseases Unit, Royal Liverpool University Hospital. 3Institute of Infection and Global Health, University of Liverpool. 4Liverpool School of Tropical Medicine

003 Taking the mickeyHelen Casey,RebeccaAnnis,ZoeRiches,O.MartinWilliamsBristol Royal Infirmary

004 An interesting case of E. coli induced urosepsis complicated by acute myopericarditisRhea O’Regan, Elaine O’Connell, Susanne O’Reilly, Tarah Cullen, Michelle MaddenMater Misericordiae University Hospital, Dublin, Ireland

005 Is it a lung cancer or pulmonary TB?Bana Hawramy, Janine Carter,ZelmaHall,AmyRobinsonBradford Teaching Hospitals NHS Foundation Trust

006 Outpatient parenteral antibiotic therapy (OPAT) for non-orthopaedic surgical infectionsAnu Rajgopal, Janine Carter, Jayne Woodhead, Lyndsay WorthingtonCalderdale and Huddersfield Foundation NHS Trust, Halifax

007 Beware, beware, of walking barefoot out there!Blair Merrick1, Thomas Jones2, Uli Schwab3

1Hospital of Tropical Diseases, London. 2Newcastle Medical School. 3Infection and Tropical Medicine, Royal Victoria Infirmary, Newcastle upon Tyne

008 One of the causes for permanent blindness in HIV patients in resource-limited settings, MyanmarNi Ni Tun1,2, Yee Yee Aung1, Thida Yamin Pyone1, Frank Smithuis1,2

1Medical Action Myanmar, Yangon, Myanmar. 2Myanmar Oxford Clinical Research Unit, Yangon, Myanmar

009 Cerebral and pulmonary nocardiosisSamantha Manyanga1, Evangelos Vryonis2, Peter Munthali3,1

1Microbiology, University Hospitals Coventry and Warwickshire NHS Trust. 2Infectious Diseases, University Hospitals Coventry and Warwickshire NHS Trust. 3University of Warwick Medical School

010 The curse of the contact lensBhamini Puvaneswaran, Manjusha Narayanan, Isha Rizal, Francisco FigueiredoThe Newcastle upon Tyne Hospitals

011 Fatal septic shock in 50 year old with unusual organism isolated in blood cultureRobert Gray, Madhuri VidwansWest Hertfordshire Hospitals, Watford

012 When is a chest infection not a chest infection?Patricia Crossey, Norman Main, Chris Keegan, Manish Gautam, Fiona McGillRoyal Liverpool Hospital

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ANTIBIOTICS AND RESISTANCE ISSUES026 The resistance mechanisms of multidrug-resistant Pseudomonas aeruginosa isolates to in

vitro cetazidime/avibactam and ceftolozane/tazobactam, in QatarMazen A. Sid Ahmed1,2, Faisal A. Khan2, Hamad A. Hadi3, Muna Al-Maslamani3, Ali Sultan4, Bo Soderquist5, Emad Ibrahim1, Jana Jass2

1Microbiology Division, Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar. 2School of Sceince and Technology, Life Sceince, Orebro University, Sweden. 3Infectious Diseases, Hamad Medical Corporation, Doha, Qatar. 4Microbiology and Immunology, Weill Cornell Medicine-Qatar, Doha, Qatar. 5School of Medical Sciences, Faculty of Medicine and Health, Orebro University, Sweden

027 Evaluation of in vitro susceptibility of multidrug-resistant Pseudomonas aeruginosa isolates from Qatar to ceftazidime/avibactam and ceftolozane/tazobactam; β-lactam/β-lactamase inhibitor combinationsMazen A. Sid Ahmed1,2, Nahla Eltai3, Jamal Hamid1, Sulieman Abu Jarir4, Hamad A. Hadi4, Muna Al-Maslamani4, Hadi Yassine3, Ali Sultan5, Bo Soderquist6, Jana Jass2, Emad Ibrahim1

1Microbiology Division, Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar. 2School of Sceince and Technology, Life Sceince, Orebro University, Sweden, 3Biomedical Research Center, Qatar University, Doha, Qatar. 4Infectious Diseases, Hamad Medical Corporation, Doha, Qatar. 5Microbiology and Immunology, Weill Cornell Medicine-Qatar, Doha, Qatar. 6School of Medical Sciences, Faculty of Medicine and Health, Orebro University, Sweden

028 Pre-admission antibiotic therapy and its effect on outcome in cases of mastoiditis: Implication for antibiotic stewardshipMitul Patel, Nikoleta Skalidi, Stephanie King, Konstance TzifaBirmingham Women’s and Children’s NHS Foundation Trust

029 Double troubleCelestine Eshiwe, Joshua York, Greta Johnson, Patrick LillieHull and East Yorkshire Hospitals

030 Tedizolid: a service evaluationGavin Barlow1,2, Joshua York1

1Hull and East Yorkshire Hospitals NHS Trust. 2Hull York Medical School

031 Vancomycin quality improvement: introducing a prescription chart across an NHS England TrustDominic Waugh1, Laura Cunliffe1, Andy Karvot2, Josh York3

1Diana Princess of Wales Hospital, Grimsby. 2North Lincolnshire & Goole NHS Trust. 3Hull Royal Infirmary

032 Outcomes of point-of-care influenza and respiratory syncytial virus testing in an Emergency DepartmentStuart Bond, Jade Lee-Milner, Christine Cruise, Sarah Robertshaw, Neil Ullyott, Emma GodfreyPinderfields Hospital, Wakefield

033 Antimicrobial prescribing behaviour in the Emergency DepartmentKathryn. M Ashton, Dorothy. J Frizelle, Stuart.E Bond, Sarah RobertshawMid Yorkshire Hospitals NHS Trust, Wakefield

034 Analysis of re-prescribing of antibiotics used for urinary tract infection in the community using routinely collected national informationWilliam Malcolm1, Alistair Beith2, Jacqueline Sneddon3

1Health Protection Scotland, NHS National Services Scotland, Glasgow. 2Information Services Division, NHS National Services Scotland, Glasgow. 3Scottish Antimicrobial Prescribing Group, Healthcare Improvement Scotland, Glasgow

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013 Snake in the grass. The challenges of diagnosing and treating tropical animal bitesMauricio Arias, Angela HoustonSt George’s Hospital NHS Trust, London

014 An overlooked cause of confusion in a patient with myasthenia gravisMarco Lee, Kavita Sethi, Aruna ChakrabartyLeeds Teaching Hospitals NHS Trust

015 Rare cause of pulmonary infection in a renal transplant recipientAng Li, Julie SamuelNewcastle upon Tyne Hospitals NHS Foundation Trust

016 Lung cancer a red herring: re-examine the evidenceSarah Salameh, Hamad Abdel Hadi, Mohd Lateef Wani, Ehab Massad, Samir Alhayassat, Faraj HowadyHamad General Hospital, Doha, Qatar

017 A beast not from the east?Samira Mohd Afzal1, Qandeel Khan2, Sannaan Irshad2, Timothy Kemp2

1Queen Elizabeth Hospital, Birmingham. 2University Hospital North Midlands, Stoke-on-Trent

018 A film with an unexpected twistThien Nguyen, Abbas See, Jane DemocratisWexham Park Hospital, Slough

019 Progressive multifocal leukoencephalopathy (PML) in immunocompetent patient secondary to carbamazepine-induced hypogammaglobulinaemiaAli Khan, Noha ElSakkaNHS Grampian, Aberdeen

020 Feeling sheepish: a rapidly progressing rash in a veterinary workerSophie Garrad, Amy RobinsonBradford Teaching Hospitals Foundation Trust

021 An unusual case of multi-organ failure in pregnancyNeil Stevenson, Aline Wilson, Nikolas RaeNinewells Hospital, Dundee

022 Primary meningococcal pericarditis: an uncommon cause of tamponadeRebecca Ward1, Martin Taylor2, Sajjad Mirza2, Hussain Contractor2

1Manchester University NHS Foundaion Trust. 2Manchester University NHS Foundation Trust

023 When infection and immunity collideStuart Taylor, James Price, Jennifer FitzpatrickRoyal Sussex County Hospital, Brighton

024 One hump or two? The case of a swollen knee in a returning travellerShuchita Soni, Francesca KnapperSouthmead Hospital, North Bristol Trust

025 A clinically challenging diagnosis in a returning traveller with pyrexia of unknown originPriya Khetarpal, Shilan Jmor, Gabriel Wallis, Naina McCann, Mike BrownHospital for Tropical Diseases, University College Hospital, London

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035 The rise of pharmacist prescribing of antibiotics in Scotland and implications for antimicrobial stewardship in ScotlandWilliam Malcolm1, Rita Nogueira2, Jacqueline Sneddon3

1Health Protection Scotland, NHS National Services Scotland, Glasgow. 2Information Services Division, NHS National Services Scotland, Edinburgh. 3Scottish Antimicrobial Prescribing Group, Healthcare Improvement Scotland, Glasgow

036 Risk factors for resistant bacteraemia in patients with suspected sepsis: cohort study using linkage of routinely collected national dataWilliam Malcolm1, Eilidh Fletcher2, Julie Wilson1, Chris Robertson1,3, Charis Marwick4

1Health Protection Scotland, NHS National Services Scotland, Glasgow. 2Information Services Division, NHS National Services Scotland, Edinburgh. 3University of Strathclyde, Glasgow. 4Population Health & Genomics, School of Medicine, University of Dundee

037 Impact of intravenous antimicrobial dose reductions on clinical outcomes in patients presenting with sepsis-induced acute kidney injury (AKI)Sabha Mahmood1, Stephen Hughes2

1Imperial College London. 2Chelsea and Westminster NHS Foundation Trust, London

038 A national survey to determine current practice regarding antimicrobial dosing in patients with sepsis-induced acute kidney injury (AKI)Sabha Mahmood1, Stephen Hughes2

1Imperial College London. 2Chelsea and Westminster NHS Foundation Trust, London

039 A qualitative survey of Antimicrobial Stewardship Practice across secondary care in LondonStephen Hughes1, Preet Panesar2

1Chelsea & Westminster NHS Hospitals, London. 2University College London Hospital

040 An evaluation of hyperkalaemia and acute kidney injury associated with in-hospital co-trimoxazole dosingStephen Hughes, Francis Edozie, Nabeela MughalChelsea & Westminster NHS Hospitals, London

041 Comparison of Mast D72C AmpC ESBL and carbapenemase detection set with the D68C AmpC and ESBL, D63C ESBL, and D69C AmpC detection sets for the identification of ESBL and AmpC activity in Enterobacterales speciesFiona Shaw, Teresa Barton, Pamela Hulme, Jane Johnson, Norma Thompson, James CargillAlder Hey Children’s Hospital, Liverpool

042 Community screening to determine the prevalence of carbapenemase producing organisms in East London, 2018Jennifer Henderson1,2, Holly Ciesielczuk1, Shona NelsonU2

1Barts Health Trust, London. 2University of the West of England, Bristol

043 Evaluating the use of the RPS antibiotic checklist by community pharmacists for potential impact on AMRAtiqah Liaqat1, Hava Nasar1, Mariam Qasim1, Aida Shiraz1, Gill Hawksworth1, Saima Afzal1, Sarah Frank1, Philip Howard2

1University of Huddersfield. 2NHS Improvement Patient Safety Team, London

044 Evaluating the impact of the KAW antimicrobial campaign among the publicAtiqah Liaqat1, Hava Nasar1, Mariam Qasim1, Aida Shiraz1, Gill Hawksworth1, Saima Afzal1, Sarah Frank1, Philip Howard2

1University of Huddersfield. 2NHS Improvement Patient Safety Team, London

045 Analysis of the use of educational material available for community pharmacists from the KAW campaignAtiqah Liaqat1, Hava Nasar1, Mariam Qasim1, Aida Shiraz1, Gill Hawksworth1, Saima Afzal1, Sarah Frank1, Philip Howard2

1University of Huddersfield. 2NHS Improvement Patient Safety Team, London

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ANTIBIOTICS AND RESISTANCE ISSUES026 The resistance mechanisms of multidrug-resistant Pseudomonas aeruginosa isolates to in

vitro cetazidime/avibactam and ceftolozane/tazobactam, in QatarMazen A. Sid Ahmed1,2, Faisal A. Khan2, Hamad A. Hadi3, Muna Al-Maslamani3, Ali Sultan4, Bo Soderquist5, Emad Ibrahim1, Jana Jass2

1Microbiology Division, Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar. 2School of Sceince and Technology, Life Sceince, Orebro University, Sweden. 3Infectious Diseases, Hamad Medical Corporation, Doha, Qatar. 4Microbiology and Immunology, Weill Cornell Medicine-Qatar, Doha, Qatar. 5School of Medical Sciences, Faculty of Medicine and Health, Orebro University, Sweden

027 Evaluation of in vitro susceptibility of multidrug-resistant Pseudomonas aeruginosa isolates from Qatar to ceftazidime/avibactam and ceftolozane/tazobactam; β-lactam/β-lactamase inhibitor combinationsMazen A. Sid Ahmed1,2, Nahla Eltai3, Jamal Hamid1, Sulieman Abu Jarir4, Hamad A. Hadi4, Muna Al-Maslamani4, Hadi Yassine3, Ali Sultan5, Bo Soderquist6, Jana Jass2, Emad Ibrahim1

1Microbiology Division, Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar. 2School of Sceince and Technology, Life Sceince, Orebro University, Sweden, 3Biomedical Research Center, Qatar University, Doha, Qatar. 4Infectious Diseases, Hamad Medical Corporation, Doha, Qatar. 5Microbiology and Immunology, Weill Cornell Medicine-Qatar, Doha, Qatar. 6School of Medical Sciences, Faculty of Medicine and Health, Orebro University, Sweden

028 Pre-admission antibiotic therapy and its effect on outcome in cases of mastoiditis: Implication for antibiotic stewardshipMitul Patel, Nikoleta Skalidi, Stephanie King, Konstance TzifaBirmingham Women’s and Children’s NHS Foundation Trust

029 Double troubleCelestine Eshiwe, Joshua York, Greta Johnson, Patrick LillieHull and East Yorkshire Hospitals

030 Tedizolid: a service evaluationGavin Barlow1,2, Joshua York1

1Hull and East Yorkshire Hospitals NHS Trust. 2Hull York Medical School

031 Vancomycin quality improvement: introducing a prescription chart across an NHS England TrustDominic Waugh1, Laura Cunliffe1, Andy Karvot2, Josh York3

1Diana Princess of Wales Hospital, Grimsby. 2North Lincolnshire & Goole NHS Trust. 3Hull Royal Infirmary

032 Outcomes of point-of-care influenza and respiratory syncytial virus testing in an Emergency DepartmentStuart Bond, Jade Lee-Milner, Christine Cruise, Sarah Robertshaw, Neil Ullyott, Emma GodfreyPinderfields Hospital, Wakefield

033 Antimicrobial prescribing behaviour in the Emergency DepartmentKathryn. M Ashton, Dorothy. J Frizelle, Stuart.E Bond, Sarah RobertshawMid Yorkshire Hospitals NHS Trust, Wakefield

034 Analysis of re-prescribing of antibiotics used for urinary tract infection in the community using routinely collected national informationWilliam Malcolm1, Alistair Beith2, Jacqueline Sneddon3

1Health Protection Scotland, NHS National Services Scotland, Glasgow. 2Information Services Division, NHS National Services Scotland, Glasgow. 3Scottish Antimicrobial Prescribing Group, Healthcare Improvement Scotland, Glasgow

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035 The rise of pharmacist prescribing of antibiotics in Scotland and implications for antimicrobial stewardship in ScotlandWilliam Malcolm1, Rita Nogueira2, Jacqueline Sneddon3

1Health Protection Scotland, NHS National Services Scotland, Glasgow. 2Information Services Division, NHS National Services Scotland, Edinburgh. 3Scottish Antimicrobial Prescribing Group, Healthcare Improvement Scotland, Glasgow

036 Risk factors for resistant bacteraemia in patients with suspected sepsis: cohort study using linkage of routinely collected national dataWilliam Malcolm1, Eilidh Fletcher2, Julie Wilson1, Chris Robertson1,3, Charis Marwick4

1Health Protection Scotland, NHS National Services Scotland, Glasgow. 2Information Services Division, NHS National Services Scotland, Edinburgh. 3University of Strathclyde, Glasgow. 4Population Health & Genomics, School of Medicine, University of Dundee

037 Impact of intravenous antimicrobial dose reductions on clinical outcomes in patients presenting with sepsis-induced acute kidney injury (AKI)Sabha Mahmood1, Stephen Hughes2

1Imperial College London. 2Chelsea and Westminster NHS Foundation Trust, London

038 A national survey to determine current practice regarding antimicrobial dosing in patients with sepsis-induced acute kidney injury (AKI)Sabha Mahmood1, Stephen Hughes2

1Imperial College London. 2Chelsea and Westminster NHS Foundation Trust, London

039 A qualitative survey of Antimicrobial Stewardship Practice across secondary care in LondonStephen Hughes1, Preet Panesar2

1Chelsea & Westminster NHS Hospitals, London. 2University College London Hospital

040 An evaluation of hyperkalaemia and acute kidney injury associated with in-hospital co-trimoxazole dosingStephen Hughes, Francis Edozie, Nabeela MughalChelsea & Westminster NHS Hospitals, London

041 Comparison of Mast D72C AmpC ESBL and carbapenemase detection set with the D68C AmpC and ESBL, D63C ESBL, and D69C AmpC detection sets for the identification of ESBL and AmpC activity in Enterobacterales speciesFiona Shaw, Teresa Barton, Pamela Hulme, Jane Johnson, Norma Thompson, James CargillAlder Hey Children’s Hospital, Liverpool

042 Community screening to determine the prevalence of carbapenemase producing organisms in East London, 2018Jennifer Henderson1,2, Holly Ciesielczuk1, Shona NelsonU2

1Barts Health Trust, London. 2University of the West of England, Bristol

043 Evaluating the use of the RPS antibiotic checklist by community pharmacists for potential impact on AMRAtiqah Liaqat1, Hava Nasar1, Mariam Qasim1, Aida Shiraz1, Gill Hawksworth1, Saima Afzal1, Sarah Frank1, Philip Howard2

1University of Huddersfield. 2NHS Improvement Patient Safety Team, London

044 Evaluating the impact of the KAW antimicrobial campaign among the publicAtiqah Liaqat1, Hava Nasar1, Mariam Qasim1, Aida Shiraz1, Gill Hawksworth1, Saima Afzal1, Sarah Frank1, Philip Howard2

1University of Huddersfield. 2NHS Improvement Patient Safety Team, London

045 Analysis of the use of educational material available for community pharmacists from the KAW campaignAtiqah Liaqat1, Hava Nasar1, Mariam Qasim1, Aida Shiraz1, Gill Hawksworth1, Saima Afzal1, Sarah Frank1, Philip Howard2

1University of Huddersfield. 2NHS Improvement Patient Safety Team, London

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046 BSAC Bacteraemia Resistance Surveillance: A five year review of non-susceptibility (2013-2017)Carolyne Horner1, Shazad Mushtaq2, BSAC Standing Committee on Resistance Surveillance1

1British Society for Antimicrobial Chemotherapy, Birmingham. 2Public Health England, London

047 BSAC Respiratory Resistance Surveillance: A review of non-susceptibility over five seasons (2012-2017)Carolyne Horner1, Shazad Mushtaq2, BSAC Standing Committee on Resistance Surveillance1

1British Society for Antimicrobial Chemotherapy, Birmingham. 2Public Health England, London

048 Experience of using a mobile app audit tool to support prescribing quality indicatorsJacqueline Sneddon1, Andrea Patton1, Mark Buchner2

1Heathcare Improvement Scotland, Glasgow. 2Tactuum, Glasgow

049 Utilisation of a national point prevalence survey of recorded penicillin allergy to inform a penicillin de-labelling processJacqueline Sneddon1, Ronald Andrew Seaton1,2, Andrea Patton1, William Malcolm3, Neil Ritchie2

1Healthcare Improvement Scotland, Glasgow. 2NHS Greater Glasgow and Clyde, Glasgow. 3Health Protection Scotland, Glasgow

050 Evaluation of current practice to inform a national antifungal stewardship programmeJacqueline Sneddon1, Brian Jones2, Ronald Andrew Seaton2,1, Andrea Patton1

1Healthcare Improvement Scotland, Glasgow. 2NHS Greater Glasgow and Clyde, Glasgow

051 Evaluating a new carbapenemase-producing Enterobacteriaecea (CPE) screening assessment tool – can we improve screening using a single question?Christopher Lander, Desmond Hsu, Maria Krutikov, Martina Cummins, Jonathan LambourneBarts Health NHS Trust, London

052 Safety and efficacy of Temocillin as a carbapenem-sparing agentKatie Heard1, Stephen Hughes1, Nabeela Mugal1,2,3, Luke Moore1,2,3

1Chelsea & Westminster NHS Hospitals, London. 2University College London Hospital. 3National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London

053 Secrets of the hospital underbelly: metagenomics of AMR in hospital sewageMeghan Perry1,2, Bram Van Bunnik2, Luke McNally2, Frank Aarestrup3, Mark Woolhouse2

1NHS Lothian, Edinburgh. 2University of Edinburgh. 3Technical University of Denmark, Copenhagen

054 An audit of admission screening for carbapenemase-producing EnterobacteriaceaeMatthew Powell1, Edward Bevan1,2, Katie Hardy2

1University of Birmingham. 2University Hospitals Birmingham NHS Foundation Trust

055 Antimicrobial prescribing - lessons from a Stroke WardMichael Sawaryn, Jonathan MooreGateshead NHS Foundation Trust

056 Drivers for meropenem prescription: a retrospective study at a large district hospital, UKAimee Goel,ZhilinJiang,TejalVaghela,HalaKandilWest Hertfordshire Hospitals NHS Trust, Watford

057 Appropriateness of antibiotic use in hospitalized patients: a retrospective study at a large district hospital, East of England, UKFarhana Ahad, Trishan Patel, Mehreen Paraouty, Tejal Vaghela, Hala KandilWest Hertfordshire Hospitals NHS Trust, Watford

058 Pre-hospital antibiotics administered by paramedics improve outcomes for patients with septic shockJon Chippendale1, Bethan Stoddart2

1Clinical Development Lead, East Midlands Ambulance Service. 2Lead Consultant Microbiologist, Path Links, North Lincolnshire and Goole NHS Trust

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059 Choosing Wisely – a synthesis of international English language infection recommendationsAlexander Richards1, Gavin Barlow1,2

1Hull and East Yorkshire NHS Trust., 2Hull York Medical School

060 “On-the-go” real time meropenem database: innovative approach to microbiologist advising with a positive impact on meropenem stewardship at a large district hospitalRobert Gray, Tejal Vaghela, Rakan El-Hamad, Madhuri Vidwans, Hala KandilWest Hertfordshire Hospitals NHS Trust, Watford

061 Collation of antimicrobial guidelines across Yorkshire and the Humber: opportunities for practice improvementAvril Lynch1, Kevin Frost2, Stuart Bond3, Jade Lee-Milner3, Kathryn Aston3

1Sheffield Teaching Hospitals NHS Foundation Trust. 2Airedale NHS Foundation Trust, Keighley. 3Mid Yorkshire Hospitals NHS Trust, Wakefield

062 Glycopeptide optimisation: a patient safety approach at a large teaching hospitalKelly Atack, Philip Howard, Abimbola Olusoga, Caroline Walker, Joseph SpencerLeeds Teaching Hospitals NHS Trust

063 Interrupted time series analysis of an antimicrobial stewardship intervention to optimise prescribing for healthcare associated pneumoniaJennifer Elias1, Kieran Lall1, Holly Lamont1, Stephen Hughes1, Luke Moore1,2,3, Katie Heard1

1Chelsea & Westminster NHS Hospitals, London. 2National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London. 3North West London Pathology, London

064 Review of the application and outcomes of the protocol for the management of pre-hospital sepsis with paramedic diagnosis and delivery of antibiotics at Isle of Wight NHS TrustEmily Macnaughton, Mel StevensIsle of Wight NHS Trust, Newport

065 Antimicrobial stewardship ward rounds using an app-based data collection tool - use in the Eastern Cape, South AfricaFrancis Collett-White1, Ya-Ying Wang2,3, Sarisha Singh2,3, Ncumisa Tafeni4, Andy Parrish4,5, David Stead4,2

1Thames Valley and Wessex Leadership Academy, Oxford. 2Frere Hospital, East London, South Africa. 3Rhodes University, Grahamstown, South Africa. 4Cecilia Makiwane Hospital, Mdantsane, South Africa. 5Walter Sisulu University, Mthatha, South Africa

066 Assessing and improving compliance with National Scottish Antimicrobial Group (SAPG) antibiotic prescribing quality indicators: a quality improvement projectEmilie BellhouseHairmyres University Hospital, East Kilbride

067 Emphasis framing and antibiotic prescribingEustacia Hamilton1, Philippa Lilford2, Fergus Hamilton3

1Weston General Hospital, Weston Super Mare. 2Severn School of Psychiatry, Bristol. 3UHBristol

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046 BSAC Bacteraemia Resistance Surveillance: A five year review of non-susceptibility (2013-2017)Carolyne Horner1, Shazad Mushtaq2, BSAC Standing Committee on Resistance Surveillance1

1British Society for Antimicrobial Chemotherapy, Birmingham. 2Public Health England, London

047 BSAC Respiratory Resistance Surveillance: A review of non-susceptibility over five seasons (2012-2017)Carolyne Horner1, Shazad Mushtaq2, BSAC Standing Committee on Resistance Surveillance1

1British Society for Antimicrobial Chemotherapy, Birmingham. 2Public Health England, London

048 Experience of using a mobile app audit tool to support prescribing quality indicatorsJacqueline Sneddon1, Andrea Patton1, Mark Buchner2

1Heathcare Improvement Scotland, Glasgow. 2Tactuum, Glasgow

049 Utilisation of a national point prevalence survey of recorded penicillin allergy to inform a penicillin de-labelling processJacqueline Sneddon1, Ronald Andrew Seaton1,2, Andrea Patton1, William Malcolm3, Neil Ritchie2

1Healthcare Improvement Scotland, Glasgow. 2NHS Greater Glasgow and Clyde, Glasgow. 3Health Protection Scotland, Glasgow

050 Evaluation of current practice to inform a national antifungal stewardship programmeJacqueline Sneddon1, Brian Jones2, Ronald Andrew Seaton2,1, Andrea Patton1

1Healthcare Improvement Scotland, Glasgow. 2NHS Greater Glasgow and Clyde, Glasgow

051 Evaluating a new carbapenemase-producing Enterobacteriaecea (CPE) screening assessment tool – can we improve screening using a single question?Christopher Lander, Desmond Hsu, Maria Krutikov, Martina Cummins, Jonathan LambourneBarts Health NHS Trust, London

052 Safety and efficacy of Temocillin as a carbapenem-sparing agentKatie Heard1, Stephen Hughes1, Nabeela Mugal1,2,3, Luke Moore1,2,3

1Chelsea & Westminster NHS Hospitals, London. 2University College London Hospital. 3National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London

053 Secrets of the hospital underbelly: metagenomics of AMR in hospital sewageMeghan Perry1,2, Bram Van Bunnik2, Luke McNally2, Frank Aarestrup3, Mark Woolhouse2

1NHS Lothian, Edinburgh. 2University of Edinburgh. 3Technical University of Denmark, Copenhagen

054 An audit of admission screening for carbapenemase-producing EnterobacteriaceaeMatthew Powell1, Edward Bevan1,2, Katie Hardy2

1University of Birmingham. 2University Hospitals Birmingham NHS Foundation Trust

055 Antimicrobial prescribing - lessons from a Stroke WardMichael Sawaryn, Jonathan MooreGateshead NHS Foundation Trust

056 Drivers for meropenem prescription: a retrospective study at a large district hospital, UKAimee Goel,ZhilinJiang,TejalVaghela,HalaKandilWest Hertfordshire Hospitals NHS Trust, Watford

057 Appropriateness of antibiotic use in hospitalized patients: a retrospective study at a large district hospital, East of England, UKFarhana Ahad, Trishan Patel, Mehreen Paraouty, Tejal Vaghela, Hala KandilWest Hertfordshire Hospitals NHS Trust, Watford

058 Pre-hospital antibiotics administered by paramedics improve outcomes for patients with septic shockJon Chippendale1, Bethan Stoddart2

1Clinical Development Lead, East Midlands Ambulance Service. 2Lead Consultant Microbiologist, Path Links, North Lincolnshire and Goole NHS Trust

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059 Choosing Wisely – a synthesis of international English language infection recommendationsAlexander Richards1, Gavin Barlow1,2

1Hull and East Yorkshire NHS Trust., 2Hull York Medical School

060 “On-the-go” real time meropenem database: innovative approach to microbiologist advising with a positive impact on meropenem stewardship at a large district hospitalRobert Gray, Tejal Vaghela, Rakan El-Hamad, Madhuri Vidwans, Hala KandilWest Hertfordshire Hospitals NHS Trust, Watford

061 Collation of antimicrobial guidelines across Yorkshire and the Humber: opportunities for practice improvementAvril Lynch1, Kevin Frost2, Stuart Bond3, Jade Lee-Milner3, Kathryn Aston3

1Sheffield Teaching Hospitals NHS Foundation Trust. 2Airedale NHS Foundation Trust, Keighley. 3Mid Yorkshire Hospitals NHS Trust, Wakefield

062 Glycopeptide optimisation: a patient safety approach at a large teaching hospitalKelly Atack, Philip Howard, Abimbola Olusoga, Caroline Walker, Joseph SpencerLeeds Teaching Hospitals NHS Trust

063 Interrupted time series analysis of an antimicrobial stewardship intervention to optimise prescribing for healthcare associated pneumoniaJennifer Elias1, Kieran Lall1, Holly Lamont1, Stephen Hughes1, Luke Moore1,2,3, Katie Heard1

1Chelsea & Westminster NHS Hospitals, London. 2National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London. 3North West London Pathology, London

064 Review of the application and outcomes of the protocol for the management of pre-hospital sepsis with paramedic diagnosis and delivery of antibiotics at Isle of Wight NHS TrustEmily Macnaughton, Mel StevensIsle of Wight NHS Trust, Newport

065 Antimicrobial stewardship ward rounds using an app-based data collection tool - use in the Eastern Cape, South AfricaFrancis Collett-White1, Ya-Ying Wang2,3, Sarisha Singh2,3, Ncumisa Tafeni4, Andy Parrish4,5, David Stead4,2

1Thames Valley and Wessex Leadership Academy, Oxford. 2Frere Hospital, East London, South Africa. 3Rhodes University, Grahamstown, South Africa. 4Cecilia Makiwane Hospital, Mdantsane, South Africa. 5Walter Sisulu University, Mthatha, South Africa

066 Assessing and improving compliance with National Scottish Antimicrobial Group (SAPG) antibiotic prescribing quality indicators: a quality improvement projectEmilie BellhouseHairmyres University Hospital, East Kilbride

067 Emphasis framing and antibiotic prescribingEustacia Hamilton1, Philippa Lilford2, Fergus Hamilton3

1Weston General Hospital, Weston Super Mare. 2Severn School of Psychiatry, Bristol. 3UHBristol

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HIV068 A case note review of chronic lung disease in patients with perinatally acquired HIV in the UK

Penny Ellis1, Paul Collini2,3, Fiona Shackley4, Kelechi Ugonna4

1University of Sheffield Medical School. 2Academic Directorate of Communicable Diseases, Sheffield Teaching Hospitals NHS Foundation Trust. 3Florey Institute and IICD, University of Sheffield. 4Sheffield Children’s NHS Foundation Trust

069 Outcomes for young people with perinatally acquired HIV infection following transition from paediatric to adult servicesPenny Ellis1, Fiona Shackley2, Julia Greig3, Claire Ryan4

1University of Sheffield Medical School. 2The Sheffield Children’s NHS Foundation Trust. 3Sheffield Teaching Hospitals NHS Foundation Trust. 4Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust

070 An 11 year-audit on newly diagnosed HIV patients in Newcastle (2007-2017): trends in late presentation and missed opportunitiesHan Hua Lim1,2, Joti Ahir3, Edmund L C Ong4,3

1Infectious Disease Unit, Hospital Umum Sarawak, Kuching, Malaysia. 2Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust. 3Newcastle University. 4Infectious Disease and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust

071 HIV testing in primary care in Newcastle: are we doing enough?Han Hua Lim1,2, Kirsty Foster3, Edmund L C Ong4,2, Brendan A I Payne2,4

1Infectious Disease Unit, Hospital Umum Sarawak, Kuching, Malaysia. 2Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust. 3Public Health England North East, Newcastle upon Tyne. 4Newcastle University

072 The recording of current non-antiretroviral medication for HIV patients at University Hospitals BirminghamErnest Mutengesa1, Meg Boothby2

1University of Birmingham. 2University Hospitals Birmingham

073 An audit to assess if the 90% target of patients attending outpatient HIV clinics have been screened for smoking history, hypertension, cardiovascular risk, renal function and bone fracture risk as per the BHIVA Standards of Care 2017Maithili Varadarajan1, Hiten Thaker2, Sarah Harrison2

1Humber and York HIV Network, Hull. 2Humber and York HIV Network, Hull

074 HIV care for an ageing cohort in a low-prevalence and largely rural area of England: patient preferences for GP communications and implications for monitoring and manageing potential drug-drug interactions (PDDI)Christie Mellor1, Jane Fraser2, Ewan Hunter2

1Newcastle University Medical School. 2Newcastle upon Tyne Hospitals NHS Foundation Trust

075 The significant of un-usually big Molluscum contagiosum in HIV patients with advanced immunodeficiency in resource limited settingsNi Ni Tun1,2, Yee Yee Aung1, Thida Yamin Pyone1, Frank Smithuis1,2

1Medical Action Myanmar, Yangon, Myanmar. 2Myanmar Oxford Clinical Research Unit, Yangon, Myanmar

076 Has the implementation of the multi-disciplinary team to HIV care led to better patient outcomes with regards to viral loads?Henry Barrington-White1,2, Hiten Thaker2, Sarah Harrison2, Lorraine Cullen2

1Hull York Medical School. 2Infectious Diseases, Castle Hill Hospital, Hull

077 Renal dysfunction from ART, sorting the horses from the zebrasVino Srirathan, Ewan HunterRoyal Victoria Infirmary, Newcastle

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HIV068 A case note review of chronic lung disease in patients with perinatally acquired HIV in the UK

Penny Ellis1, Paul Collini2,3, Fiona Shackley4, Kelechi Ugonna4

1University of Sheffield Medical School. 2Academic Directorate of Communicable Diseases, Sheffield Teaching Hospitals NHS Foundation Trust. 3Florey Institute and IICD, University of Sheffield. 4Sheffield Children’s NHS Foundation Trust

069 Outcomes for young people with perinatally acquired HIV infection following transition from paediatric to adult servicesPenny Ellis1, Fiona Shackley2, Julia Greig3, Claire Ryan4

1University of Sheffield Medical School. 2The Sheffield Children’s NHS Foundation Trust. 3Sheffield Teaching Hospitals NHS Foundation Trust. 4Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust

070 An 11 year-audit on newly diagnosed HIV patients in Newcastle (2007-2017): trends in late presentation and missed opportunitiesHan Hua Lim1,2, Joti Ahir3, Edmund L C Ong4,3

1Infectious Disease Unit, Hospital Umum Sarawak, Kuching, Malaysia. 2Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust. 3Newcastle University. 4Infectious Disease and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust

071 HIV testing in primary care in Newcastle: are we doing enough?Han Hua Lim1,2, Kirsty Foster3, Edmund L C Ong4,2, Brendan A I Payne2,4

1Infectious Disease Unit, Hospital Umum Sarawak, Kuching, Malaysia. 2Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust. 3Public Health England North East, Newcastle upon Tyne. 4Newcastle University

072 The recording of current non-antiretroviral medication for HIV patients at University Hospitals BirminghamErnest Mutengesa1, Meg Boothby2

1University of Birmingham. 2University Hospitals Birmingham

073 An audit to assess if the 90% target of patients attending outpatient HIV clinics have been screened for smoking history, hypertension, cardiovascular risk, renal function and bone fracture risk as per the BHIVA Standards of Care 2017Maithili Varadarajan1, Hiten Thaker2, Sarah Harrison2

1Humber and York HIV Network, Hull. 2Humber and York HIV Network, Hull

074 HIV care for an ageing cohort in a low-prevalence and largely rural area of England: patient preferences for GP communications and implications for monitoring and manageing potential drug-drug interactions (PDDI)Christie Mellor1, Jane Fraser2, Ewan Hunter2

1Newcastle University Medical School. 2Newcastle upon Tyne Hospitals NHS Foundation Trust

075 The significant of un-usually big Molluscum contagiosum in HIV patients with advanced immunodeficiency in resource limited settingsNi Ni Tun1,2, Yee Yee Aung1, Thida Yamin Pyone1, Frank Smithuis1,2

1Medical Action Myanmar, Yangon, Myanmar. 2Myanmar Oxford Clinical Research Unit, Yangon, Myanmar

076 Has the implementation of the multi-disciplinary team to HIV care led to better patient outcomes with regards to viral loads?Henry Barrington-White1,2, Hiten Thaker2, Sarah Harrison2, Lorraine Cullen2

1Hull York Medical School. 2Infectious Diseases, Castle Hill Hospital, Hull

077 Renal dysfunction from ART, sorting the horses from the zebrasVino Srirathan, Ewan HunterRoyal Victoria Infirmary, Newcastle

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MYCOLOGY078 Molecular characterization of Candida species associated with human urinary tract infection

Muhammad Mushtaq,ZilEHumaBalochistan University of Information Technology, Information Technology, Engineering, Management Sciences (BUITEMS), Quetta, Pakistan

079 Laboratory evaluation of a new T2 Magnetic Resonance assay for rapid detection of Candida species in spiked human blood samplesAlireza Abdolrasouli, Nita Fatania, Giovanni SattaNorth West London Pathology, Imperial College Healthcare NHS Trust, London

080 Candida auris molecular detection in epidemiological surveillance samples by OLM Diagnostics AurisID kitCarme Salvador Garcia1, Nuria Tormo Palop1, Roberto Olmos Arenas1, Juan Vicente Mulet Bayona1, Gemma Johnson2, Concepción Gimeno Cardona1,3

1Consorcio Hospital General Universitario de Valencia, Spain. 2OLM Diagnostics, Newcastle. 3Medicine School, University of Valencia, Spain

081 Comparison of three commercial susceptibility testing panels for the determination of minimum inhibitory concentrations of antifungals against Candida speciesJane Johnson, Susie Batley, James CargillAlder Hey Children’s Hospital, Liverpool

082 Case study of Malassezia pachydermatis in an adolescent undergoing chemotherapyAmy Aice CarsonUniversity Hospitals Bristol NHS Foundation Trust

083 Impact of invasive Candidiasis in a Paediatric Transplant UnitRichard Capstick, Isha Rizal, Caroline Williams, Hloniphani Mpofu, Joanna Lumb, Yamura Thiru, Julie SamuelNewcastle upon Tyne Hospitals

084 An unusual cause of intracranial mass lesions in an immuno-competent adultPhoebe Cross, Hugh McGann, Penelope LewthwaiteLeeds Teaching Hospitals

085 Common commensal or uncommon calamity?Aarti Velani, Liz HartNottingham University Hospitals

VIRAL HEPATITIS + GENERAL VIROLOGY086 Clinical and economic impact of point-of-care test for influenza in the Emergency

DepartmentShabnam Iyer1, Steffan Glaze1, Live Thorsen1, Jo Jefferies2

1Royal Berkshire NHS Foundation Trust, Reading. 2Public Health Services for Berkshire, Reading

087 Disseminated adenovirus Type 7 infection causing acute respiratory distress in immunocompetent adults: a case series from an intensive care unit in North West EnglandTomWingfield1,2,3,4, Luke Dearden1, Pete Calvert1, Orod Osanlou1, Brian Johnston1, Anu Chawla1, Ian Hart1, Lance Turtle1,4, Richard Wenstone1

1Royal Liverpool and Broadgreen University Hospitals NHS Trust. 2Karolinska Institutet, Stockholm, Sweden. 3Liverpool School of Tropical Medicine. 4University of Liverpool

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088 Pilot study for introduction of point of care (POC) rapid molecular testing of respiratory viruses at a remote District General Hospital during the winter season 2017-18Annika Graham, Noha ElSakkaNHS Grampian, Aberdeen

089 Introduction of rapid molecular testing of respiratory viruses at acute medical admission during the winter season 2017-18Robin Brittain-Long, Noha ElsakkaNHS Grampian, Aberdeen

090 Nanopore detection of influenza virus direct from respiratory samplesKuiama Lewandowski1, Yifei Xu2,3, Sheila Lumley4,5, Ali Vaughan3, Richard Vipond1, Miles Carroll1, Sarah Walker3, Peter Simmonds5, Dona Foster3, Tim Peto4,3,2, Derrick Crook3,2,4, Philippa Matthews5,4, Steven Pullan1

1Public Health England, National Infection Service, Porton Down. 2Nuffield Department of Medicine, University of Oxford. 3NIHR Oxford Biomedical Research Centre, University of Oxford. 4Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford. 5Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford

091 Setting up point of care testing for influenza and RSV on the Acute Admissions Unit of a Tertiary Referral Hospital; experience of three years of testingShirelle Burton-Fanning, Sheila Waugh, Ashley Price, Jayne Harwood, Brendan Payne, Chris GibbinsNewcastle upon Tyne Hospitals NHS Foundation Trust

092 Evaluating the clinical efficacy of weekend flu testing at Chelsea and Westminster HospitalWilliam Hurt1, Joshua Elliott1, Paul Randel2, Luke Moore1

1Chelsea Westminster Hospital, London. 2Imperial College London

093 Audit: Clinical and laboratory correlation of a detected Hepatitis A IgM antibody from a screening serology testMihaela Petric, Joel PaulPennine Acute Trust, Royal Oldham Hospital, Microbiology/Virology Department, Manchester

TRAVEL AND TROPICAL MEDICINE094 Case report: A returning traveller with meningism after a long haul flight – an unusual

presentation of multiple acyl-CoA dehydrogenase deficiency (MADD)Paul Hine1,2, Anna Stewart2, Joseph Taylor2, Andreas Trimidas2, Sylviane Defres3,2

1Liverpool School of Tropical Medicine. 2Royal Liverpool and Broadgreen University Hospitals Trust. 3Institute of Global Health, Liverpool

095 Once, twice, is three times always necessary? A UK single-centre retrospective analysis of malaria diagnosticsBlair Merrick1, John Lambert2, Caolan Duffy3, Tom Hepburn3, Matthias Schmid4

1Hospital for Tropical Diseases, London. 2Blood Sciences, Royal Victoria Infirmary, Newcastle upon Tyne. 3Newcastle Medical School. 4Infection and Tropical Medicine, Royal Victoria Infirmary, Newcastle upon Tyne

096 Double trouble from ColumbiaStephen Woolley1,2, Jayne Jones1, Nicholas Beeching2

1Liverpool School of Tropical Medicine, L. 2TIDU, Royal Liverpool Hospital

097 Soldier soldierStephen Woolley1,2,3, Keri McLean1, Timothy Elmer4, Dennis Freshwater5, Lucy Lamb6,7

1TIDU, Royal Liverpool Hospital. 2Liverpool School of Tropical Medicine. 3Institute of Naval Medicine, Portsmouth. 4Defence Public Health Unit, Lichfield. 5Royal Centre of Defence Medicine, Birmingham. 6Infection, Royal Free Hospital, London. 7Academic Department of Military Medicine, Royal Centre of Defence Medicine, Birmingham

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098 One year of advice calls to a tropical and infectious diseases referral centre: a retrospective, descriptive analysis from Liverpool, EnglandTomWingfield1,2,3,4, Mike Beadsworth1,2, Nick Beeching2,1, Emmanuel Nsutebu1

1Royal Liverpool and Broadgreen University Hospitals NHS Trust. 2Liverpool School of Tropical Medicine. 3Karolinska Institutet, Stockholm, Sweden. 4University of Liverpool

099 An aetiological study of acute encephalitis syndrome in children in Karnataka State, South IndiaLance Turtle1,2, Gemma Buxton3, Mohammed Hussain4, Raquel Medialdea-Carrera1, Heather Isenman5, Jason Lee6, Tehmina Bharucha7, Bhagteshwar Singh2, Vishali Satishkumar4, Srinivasa Krishna4, M Veera-Shankar4, Vasanthapuram Ravi8, Vijaya Satchidanadam9, MikeGriffiths2,1, Tom Solomon2,1

1NIHR Health Protection Research Unit for Emerging and Zoonotic Infections, University of Liverpool. 2NIHR Global Health Research Group in CNS Infections, University of Liverpool. 3Royal Hospital for Sick Children, Edinburgh. 4Vijayanagar Institute of Medical Science (VIMS) Medical College, Bellary, India. 5Infectious Diseases, Christchurch Hospital, New Zealand. 6University of Liverpool. 7Infectious Diseases, Royal Free Hospital, London. 8Neurovirology, National Institute of Mental Health and Neurosciences, Bangalore, India. 9Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India

100 The United Kingdom’s experience of Zika virus infection (2016 - 2017)Christina Petridou,ZaneetaDhesi,EmmaAaronsRare and Imported Pathogens Laboratory, PHE Porton Down, Salisbury

101 Fever, rash and hepatitis; what’s the differential?Francesca Knapper, Megan Jenkins, Mahableshwar Albur, Izak HeysSouthmead Hospital, Bristol

102 A case of non-falciparum malaria diagnosed on screening of donated blood 10 years after possible exposureMegan Jenkins, Francesca KnapperSouthmead Hospital, Bristol

103 Where do medical students travel to on elective? An analysis of Newcastle University Medical School student elective travel 2006-2017Victoria Parris1, Karen Smith2, Matthias Schmid3

1Royal Victoria Infirmary, Newcastle. 2School of Medical Education, Newcastle University. 3Royal Victoria Infirmary, Newcastle

104 Uptake and reasons for refusal of travel vaccine recommendations in 1329 new attendances at the Sheffield Travel Health ClinicNaomi Meardon1, Jacqueline Clark1, Amy Worthington1, Vicky Goodall1, Cariad Evans1, Tom Darton1,2

1Sheffield Teaching Hospitals NHS Foundation Trust. 2University of Sheffield

105 Is it time to review the need for serial blood films in the diagnosis of malaria?Daniella Ross, Rebecca SutherlandRegional Infectious Diseases Unit, Western General Hospital, Edinburgh

106 Pancytopenia and fever post-chemotherapy for gestational trophoblastic diseaseElena Ferran1, Christopher Chiu2, Ho Kwong Li1, Paul Middleton1, Frances Sanderson1, Aula Abbara1

1Imperial College Healthcare NHS Trust, London. 2Imperial College London

107 The association between high risk countries for Strongyloides stercoralis infection and gram-negative bacteraemia in patients with renal transplantsDaniel Pan, Paul Arkell, Stephan Brincat, Catherine A. CosgroveSt George’s Hospital, London

108 Strongly suspect this diagnosis in the renal transplant patient with acute shortness of breathDaniel Pan, Paul Arkell, Neil Stone, Catherine A. CosgroveSt George’s Hospital, London

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098 One year of advice calls to a tropical and infectious diseases referral centre: a retrospective, descriptive analysis from Liverpool, EnglandTomWingfield1,2,3,4, Mike Beadsworth1,2, Nick Beeching2,1, Emmanuel Nsutebu1

1Royal Liverpool and Broadgreen University Hospitals NHS Trust. 2Liverpool School of Tropical Medicine. 3Karolinska Institutet, Stockholm, Sweden. 4University of Liverpool

099 An aetiological study of acute encephalitis syndrome in children in Karnataka State, South IndiaLance Turtle1,2, Gemma Buxton3, Mohammed Hussain4, Raquel Medialdea-Carrera1, Heather Isenman5, Jason Lee6, Tehmina Bharucha7, Bhagteshwar Singh2, Vishali Satishkumar4, Srinivasa Krishna4, M Veera-Shankar4, Vasanthapuram Ravi8, Vijaya Satchidanadam9, MikeGriffiths2,1, Tom Solomon2,1

1NIHR Health Protection Research Unit for Emerging and Zoonotic Infections, University of Liverpool. 2NIHR Global Health Research Group in CNS Infections, University of Liverpool. 3Royal Hospital for Sick Children, Edinburgh. 4Vijayanagar Institute of Medical Science (VIMS) Medical College, Bellary, India. 5Infectious Diseases, Christchurch Hospital, New Zealand. 6University of Liverpool. 7Infectious Diseases, Royal Free Hospital, London. 8Neurovirology, National Institute of Mental Health and Neurosciences, Bangalore, India. 9Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India

100 The United Kingdom’s experience of Zika virus infection (2016 - 2017)Christina Petridou,ZaneetaDhesi,EmmaAaronsRare and Imported Pathogens Laboratory, PHE Porton Down, Salisbury

101 Fever, rash and hepatitis; what’s the differential?Francesca Knapper, Megan Jenkins, Mahableshwar Albur, Izak HeysSouthmead Hospital, Bristol

102 A case of non-falciparum malaria diagnosed on screening of donated blood 10 years after possible exposureMegan Jenkins, Francesca KnapperSouthmead Hospital, Bristol

103 Where do medical students travel to on elective? An analysis of Newcastle University Medical School student elective travel 2006-2017Victoria Parris1, Karen Smith2, Matthias Schmid3

1Royal Victoria Infirmary, Newcastle. 2School of Medical Education, Newcastle University. 3Royal Victoria Infirmary, Newcastle

104 Uptake and reasons for refusal of travel vaccine recommendations in 1329 new attendances at the Sheffield Travel Health ClinicNaomi Meardon1, Jacqueline Clark1, Amy Worthington1, Vicky Goodall1, Cariad Evans1, Tom Darton1,2

1Sheffield Teaching Hospitals NHS Foundation Trust. 2University of Sheffield

105 Is it time to review the need for serial blood films in the diagnosis of malaria?Daniella Ross, Rebecca SutherlandRegional Infectious Diseases Unit, Western General Hospital, Edinburgh

106 Pancytopenia and fever post-chemotherapy for gestational trophoblastic diseaseElena Ferran1, Christopher Chiu2, Ho Kwong Li1, Paul Middleton1, Frances Sanderson1, Aula Abbara1

1Imperial College Healthcare NHS Trust, London. 2Imperial College London

107 The association between high risk countries for Strongyloides stercoralis infection and gram-negative bacteraemia in patients with renal transplantsDaniel Pan, Paul Arkell, Stephan Brincat, Catherine A. CosgroveSt George’s Hospital, London

108 Strongly suspect this diagnosis in the renal transplant patient with acute shortness of breathDaniel Pan, Paul Arkell, Neil Stone, Catherine A. CosgroveSt George’s Hospital, London

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109 Intestinal parasitic infections in primary school children in Umuahia South, LGA Abia State, NigeriaOnyinye Ukpai, Eze ThankGodZoology and Environmental Biology, Michael Okpara University of Agriculture, Umudike, Umuahia, Nigeria

110 Investigating the utilisation of Rare and Imported Pathogens Laboratory testing through a hub-and-spoke model of laboratory practiceAroon Bhardwaj Shah1, Umar Ebrahimsa2, Scott Pallett2, Nabeela Mughal2,3, Luke SP Moore2,3,4

1Imperial College School of Medicine, Imperial College London. 2Microbiology & Infectious Diseases, Chelsea and Westminster Hospital, London. 3North West London Pathology, Imperial College Healthcare NHS Trust. 4National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London

111 Investigation and initial management of suspected MERS in patients admitted to Chelsea and Westminster Hospital between August 2017 and September 2018Katherine Lewis1, Umar Ebrahimsa2, Scott Pallett2, Nabeela Mughal2,3, Luke Moore2,3,4

1Imperial College School of Medicine, Imperial College London. 2Microbiology & Infectious Diseases, Chelsea and Westminster Hospital, London. 3North West London Pathology, Imperial College Healthcare NHS Trust. 4National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London

GENERAL BACTERIOLOGY112 Use of MALDI-Tof for the identification of non fermenting gram negative rods in cystic

fibrosisRachel Austin-Hutchison, James GreigUniversities Hospital Plymouth

113 E. coli blood stream infection – a 6 month prospective observational seriesPatrick Lillie, Greta Johnson, Monica Ivan, Peter MossInfection, Hull and East Yorkshire Hospitals NHS Trust

114 Necrotising otitis externa: lessons learnt from a large retrospective cohortSusanne Hodgson1,2, Victoria Sinclair2, Monique Andersson2

1University of Oxford. 2Oxford University Hospitals NHS Foundation Trust

115 Endocarditis in injecting drug users in the North East of EnglandChris Lawrence, Brendan MacCarronSouth Tees Hospitals, Middlesbrough

116 A service evaluation of prevention and management of ventricular assist device (VAD) infections in a UK specialist cardiothoracic centreVanessa Wong1, Sumita Pai2, Ruth Kappeler2, Olly Allen2, Huina Yang2

1Addenbrooke’s Hospital, Cambridge, 2Royal Papworth Hospital, Cambridge

117 Multi-centre study of the in vitro activity of ceftolozane/tazobactam and other commonly used antibiotics against Pseudomonas aeruginosa isolates from patients in the United KingdomAdela Alvarez-Buylla1, Mike Allen1, Dan Betts1, Irene Monahan2, Tim Plance2

1MSD Ltd, Hoddesdon, 2St George’s University Hospital, London

118 For the record: annual audit as a tool to improve patient handover and the quality of microbiology reportsKatherine WaltonMicrobiology, The Newcastle upon Tyne Hospitals NHS Foundation Trust

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109 Intestinal parasitic infections in primary school children in Umuahia South, LGA Abia State, NigeriaOnyinye Ukpai, Eze ThankGodZoology and Environmental Biology, Michael Okpara University of Agriculture, Umudike, Umuahia, Nigeria

110 Investigating the utilisation of Rare and Imported Pathogens Laboratory testing through a hub-and-spoke model of laboratory practiceAroon Bhardwaj Shah1, Umar Ebrahimsa2, Scott Pallett2, Nabeela Mughal2,3, Luke SP Moore2,3,4

1Imperial College School of Medicine, Imperial College London. 2Microbiology & Infectious Diseases, Chelsea and Westminster Hospital, London. 3North West London Pathology, Imperial College Healthcare NHS Trust. 4National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London

111 Investigation and initial management of suspected MERS in patients admitted to Chelsea and Westminster Hospital between August 2017 and September 2018Katherine Lewis1, Umar Ebrahimsa2, Scott Pallett2, Nabeela Mughal2,3, Luke Moore2,3,4

1Imperial College School of Medicine, Imperial College London. 2Microbiology & Infectious Diseases, Chelsea and Westminster Hospital, London. 3North West London Pathology, Imperial College Healthcare NHS Trust. 4National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London

GENERAL BACTERIOLOGY112 Use of MALDI-Tof for the identification of non fermenting gram negative rods in cystic

fibrosisRachel Austin-Hutchison, James GreigUniversities Hospital Plymouth

113 E. coli blood stream infection – a 6 month prospective observational seriesPatrick Lillie, Greta Johnson, Monica Ivan, Peter MossInfection, Hull and East Yorkshire Hospitals NHS Trust

114 Necrotising otitis externa: lessons learnt from a large retrospective cohortSusanne Hodgson1,2, Victoria Sinclair2, Monique Andersson2

1University of Oxford. 2Oxford University Hospitals NHS Foundation Trust

115 Endocarditis in injecting drug users in the North East of EnglandChris Lawrence, Brendan MacCarronSouth Tees Hospitals, Middlesbrough

116 A service evaluation of prevention and management of ventricular assist device (VAD) infections in a UK specialist cardiothoracic centreVanessa Wong1, Sumita Pai2, Ruth Kappeler2, Olly Allen2, Huina Yang2

1Addenbrooke’s Hospital, Cambridge, 2Royal Papworth Hospital, Cambridge

117 Multi-centre study of the in vitro activity of ceftolozane/tazobactam and other commonly used antibiotics against Pseudomonas aeruginosa isolates from patients in the United KingdomAdela Alvarez-Buylla1, Mike Allen1, Dan Betts1, Irene Monahan2, Tim Plance2

1MSD Ltd, Hoddesdon, 2St George’s University Hospital, London

118 For the record: annual audit as a tool to improve patient handover and the quality of microbiology reportsKatherine WaltonMicrobiology, The Newcastle upon Tyne Hospitals NHS Foundation Trust

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119 BactiVac, a network to support the study, development and implementation of bacterial vaccinesAlex G Richter1, Johanna E Dean1, Susan Pope1, Evelina Balandyte1, Adam F Cunningham1, Calman A MacLennan1,2,3

1University of Birmingham. 2University of Oxford. 3Bill and Melinda Gates Foundation, Seattle, USA

120 From laboratory to clinical practice- invasive pneumococcal infection at a London Teaching HospitalLuciana Sowole, Clare Logan, Kirstin Khonyongwa, Amanda FifeKing’s College Hospital, London

121 Multi-disciplinary infective endocarditis ward round findings from University Hospitals Coventry and Warwickshire NHS Trust 2016-2018Samantha Manyanga1, Harry Thynne1, Evangelos Vryonis2, Vjeran Cajic2, Fionnula Stalker3, Peter. E. Glennon4, Peter Munthali1,5

1Microbiology, University Hospitals Coventry and Warwickshire NHS Trust. 2Infectious Diseases, University Hospitals Coventry and Warwickshire NHS Trust. 3Pharmacy, University Hospitals Coventry and Warwickshire NHS Trust. 4Cardiology, University Hospitals Coventry and Warwickshire NHS Trust. 5University of Warwick Medical School

122 Mitral and aortic valve infective endocarditis with cerebral complications in endocarditis patients at University Hospitals Coventry and Warwickshire NHS TrustSamantha Manyanga1, Harry Thynne1, Evangelos Vryonis2, Vjeran Cajic2, Peter E Glennon3, Peter Munthali4,1

1Microbiology, University Hospitals Coventry and Warwickshire NHS Trust. 2Infectious Diseases, University Hospitals Coventry and Warwickshire NHS Trust. 3Cardiology, University Hospitals Coventry and Warwickshire NHS Trust. 4University of Warwick Medical School

123 Clinical and laboratory characteristics of invasive Aeromonasinfection in a UK Teaching Hospital: a 20-year retrospective reviewSwapna Motukupally, Nelun PereraLeicester Royal Infirmary, United Hospitals of Leicester

124 9 years experience of Staphylococcus aureus bacteraemia in haemodialysis patients at a London Teaching HospitalAnn Sturdy1, Stephen Mepham1, Shara Palanivel1, Jennifer Cross2, Sophie Collier1

1Microbiology, Royal Free Hospital, London. 2UCL Centre for Nephrology, Royal Free, London

125 MSSA reduction strategies in Paediatric Cardiothoracic Transplant Unit, Newcastle upon Tyne Hospitals NHS Foundation TrustSimon Dewar, Hloniphani Mpofu, Julie Samuel, Joanna LumbThe Newcastle Upon Tyne Hospitals NHS Trust

126 Audit of maternity and microbiology flowchart guidance for management of UTI in pregnancySimon Dewar, Munjusha Narayanan, Elizabeth Nevins, Racheal Roe, Philipa MarsdenThe Newcastle Upon Tyne Hospitals NHS Trust

127 Brucella post-exposure management in laboratory settings: a systematic reviewAstrid Tulsson1,TomWingfield1,2, Nick Beeching1

1Liverpool School of Tropical Medicine. 2University of Liverpool

128 Prevalence, microbiological and epidemiological characterisation of clinical meningitis in children. Experience from Infectious Diseases tertiary referral centre, EgyptAsmaa Farrag1, Noha Elsakka2, Bayoumi Gharib3, Elham Elsakka3

1Alexandria University Children’s Hospital, Alexandria, Egypt. 2NHS Grampian, Aberdeen. 3Alexandria Faculty of Medicine, Alexandria, Egypt

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119 BactiVac, a network to support the study, development and implementation of bacterial vaccinesAlex G Richter1, Johanna E Dean1, Susan Pope1, Evelina Balandyte1, Adam F Cunningham1, Calman A MacLennan1,2,3

1University of Birmingham. 2University of Oxford. 3Bill and Melinda Gates Foundation, Seattle, USA

120 From laboratory to clinical practice- invasive pneumococcal infection at a London Teaching HospitalLuciana Sowole, Clare Logan, Kirstin Khonyongwa, Amanda FifeKing’s College Hospital, London

121 Multi-disciplinary infective endocarditis ward round findings from University Hospitals Coventry and Warwickshire NHS Trust 2016-2018Samantha Manyanga1, Harry Thynne1, Evangelos Vryonis2, Vjeran Cajic2, Fionnula Stalker3, Peter. E. Glennon4, Peter Munthali1,5

1Microbiology, University Hospitals Coventry and Warwickshire NHS Trust. 2Infectious Diseases, University Hospitals Coventry and Warwickshire NHS Trust. 3Pharmacy, University Hospitals Coventry and Warwickshire NHS Trust. 4Cardiology, University Hospitals Coventry and Warwickshire NHS Trust. 5University of Warwick Medical School

122 Mitral and aortic valve infective endocarditis with cerebral complications in endocarditis patients at University Hospitals Coventry and Warwickshire NHS TrustSamantha Manyanga1, Harry Thynne1, Evangelos Vryonis2, Vjeran Cajic2, Peter E Glennon3, Peter Munthali4,1

1Microbiology, University Hospitals Coventry and Warwickshire NHS Trust. 2Infectious Diseases, University Hospitals Coventry and Warwickshire NHS Trust. 3Cardiology, University Hospitals Coventry and Warwickshire NHS Trust. 4University of Warwick Medical School

123 Clinical and laboratory characteristics of invasive Aeromonasinfection in a UK Teaching Hospital: a 20-year retrospective reviewSwapna Motukupally, Nelun PereraLeicester Royal Infirmary, United Hospitals of Leicester

124 9 years experience of Staphylococcus aureus bacteraemia in haemodialysis patients at a London Teaching HospitalAnn Sturdy1, Stephen Mepham1, Shara Palanivel1, Jennifer Cross2, Sophie Collier1

1Microbiology, Royal Free Hospital, London. 2UCL Centre for Nephrology, Royal Free, London

125 MSSA reduction strategies in Paediatric Cardiothoracic Transplant Unit, Newcastle upon Tyne Hospitals NHS Foundation TrustSimon Dewar, Hloniphani Mpofu, Julie Samuel, Joanna LumbThe Newcastle Upon Tyne Hospitals NHS Trust

126 Audit of maternity and microbiology flowchart guidance for management of UTI in pregnancySimon Dewar, Munjusha Narayanan, Elizabeth Nevins, Racheal Roe, Philipa MarsdenThe Newcastle Upon Tyne Hospitals NHS Trust

127 Brucella post-exposure management in laboratory settings: a systematic reviewAstrid Tulsson1,TomWingfield1,2, Nick Beeching1

1Liverpool School of Tropical Medicine. 2University of Liverpool

128 Prevalence, microbiological and epidemiological characterisation of clinical meningitis in children. Experience from Infectious Diseases tertiary referral centre, EgyptAsmaa Farrag1, Noha Elsakka2, Bayoumi Gharib3, Elham Elsakka3

1Alexandria University Children’s Hospital, Alexandria, Egypt. 2NHS Grampian, Aberdeen. 3Alexandria Faculty of Medicine, Alexandria, Egypt

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129 The clinical management of malignant otitis externa - a review of the last 20 cases presenting to NHS Lothian and development of a joint management protocol with ENTNaomi Henderson1, Rebecca Sutherland2

1Lothian Infection Service, Royal Infirmary Edinburgh. 2Lothian Infection Service, Western General Hospital, Edinburgh

130 Infective endocarditis caused by Panton-Valentine leukocidin producing methicillin-susceptible Staphylococcus aureus: first reported case in United KingdomChathuri Gunasekera1,2, Ian Gould1,3, Marjory Greig1

1Aberdeen Royal Infirmary. 2University of Colombo, Sri Lanka. 3University of Aberdeen

131 Prosthetic vascular graft infections at a UK Tertiary Vascular CentreStephanie Harris1, Ishapreet Kaur2, Janice Tsui3, Sophie Collier3

1King’s College Hospital, London. 2Royal College of Surgeons in Ireland, Dublin. 3Royal Free Hospital, London

132 An unusual cause of osteomyelitis in a 17-year-oldVictoria Shivji1, Shiu-Shing Soo2, Susan Snape3

1Infectious Diseases, Nottingham City Hospital. 2Clinical Microbiology, QMC, Nottingham. 3OPAT and Clinical Microbiology, Nottingham

133 Diabetic foot osteomyelitis treatment: a service review of success rates involving patients requiring intravenous antibiotics for resolution of their osteomyelitis and wound healing. 4 factors were specifically studied: location of osteomyelitis, presence/absence of peripheral vascular disease, failure of prior oral antibiotics and number and type of organisms culturedSusan Snape, Hannah Bond, Lisa Metcalf, Ravikanth GouniNottingham University Hospitals NHS Trust

134 Can whole genome sequencing and maldi-tof identify vancomycin resistant enterococci transmission events in haematology inpatients?Sarah Coleman1, Emma Boldock2, David Partridge1

1Sheffield Teaching Hospital Foundation Trust. 2Royal United Hospitals Bath NHS Foundation Trust

PUBLIC HEALTH AND EPIDEMIOLOGY, IPC + OPAT 135 Preoperative MRSA screening in oncoplastic breast reconstruction

Yan Yu Tan, Jessica Chang, Kathryn Dickson, Mihir Chandarana, Soni Soumian, Sankaran Narayanan, Sekhar MarlaUniversity Hospital of North Midlands, Stoke-on-Trent

136 Analysis of vascular access device (VAD) infection incidence in NHS LothianOmome Etomi1, Donald Inverarity2, Janathan Danial2, Luke Tysall21Croydon Univeristy Hospital Trust, London. 2NHS Lothian, Edinburgh

137 Infection control issues arising in the care of a patient with yellow fever: a UK hospital’s experienceCharlotte Patterson, Michael JacobsRoyal Free Hospital, London

138 The impact of an online microbiology referral service on departmental workload and on efficiency savingsFaisal Bin-Reza, Christi Atkinson, Justin Edwards, Mustafa Awad-el-kariemBasildon & Thurrock University Hospital

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129 The clinical management of malignant otitis externa - a review of the last 20 cases presenting to NHS Lothian and development of a joint management protocol with ENTNaomi Henderson1, Rebecca Sutherland2

1Lothian Infection Service, Royal Infirmary Edinburgh. 2Lothian Infection Service, Western General Hospital, Edinburgh

130 Infective endocarditis caused by Panton-Valentine leukocidin producing methicillin-susceptible Staphylococcus aureus: first reported case in United KingdomChathuri Gunasekera1,2, Ian Gould1,3, Marjory Greig1

1Aberdeen Royal Infirmary. 2University of Colombo, Sri Lanka. 3University of Aberdeen

131 Prosthetic vascular graft infections at a UK Tertiary Vascular CentreStephanie Harris1, Ishapreet Kaur2, Janice Tsui3, Sophie Collier3

1King’s College Hospital, London. 2Royal College of Surgeons in Ireland, Dublin. 3Royal Free Hospital, London

132 An unusual cause of osteomyelitis in a 17-year-oldVictoria Shivji1, Shiu-Shing Soo2, Susan Snape3

1Infectious Diseases, Nottingham City Hospital. 2Clinical Microbiology, QMC, Nottingham. 3OPAT and Clinical Microbiology, Nottingham

133 Diabetic foot osteomyelitis treatment: a service review of success rates involving patients requiring intravenous antibiotics for resolution of their osteomyelitis and wound healing. 4 factors were specifically studied: location of osteomyelitis, presence/absence of peripheral vascular disease, failure of prior oral antibiotics and number and type of organisms culturedSusan Snape, Hannah Bond, Lisa Metcalf, Ravikanth GouniNottingham University Hospitals NHS Trust

134 Can whole genome sequencing and maldi-tof identify vancomycin resistant enterococci transmission events in haematology inpatients?Sarah Coleman1, Emma Boldock2, David Partridge1

1Sheffield Teaching Hospital Foundation Trust. 2Royal United Hospitals Bath NHS Foundation Trust

PUBLIC HEALTH AND EPIDEMIOLOGY, IPC + OPAT 135 Preoperative MRSA screening in oncoplastic breast reconstruction

Yan Yu Tan, Jessica Chang, Kathryn Dickson, Mihir Chandarana, Soni Soumian, Sankaran Narayanan, Sekhar MarlaUniversity Hospital of North Midlands, Stoke-on-Trent

136 Analysis of vascular access device (VAD) infection incidence in NHS LothianOmome Etomi1, Donald Inverarity2, Janathan Danial2, Luke Tysall21Croydon Univeristy Hospital Trust, London. 2NHS Lothian, Edinburgh

137 Infection control issues arising in the care of a patient with yellow fever: a UK hospital’s experienceCharlotte Patterson, Michael JacobsRoyal Free Hospital, London

138 The impact of an online microbiology referral service on departmental workload and on efficiency savingsFaisal Bin-Reza, Christi Atkinson, Justin Edwards, Mustafa Awad-el-kariemBasildon & Thurrock University Hospital

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139 Awareness and understanding amongst a university student population of a community pharmacy public health campaign in Scotland aimed at encouraging the responsible use of antibioticsAntonella P. Tonna1, Anita E. Weidmann1, Ina Donat1, Jacqueline Sneddon2, Alison Cockburn3, Derek Stewart1

1School of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen. 2Health Improvement Scotland, Glasgow. 3NHS Lothian, Western General Hospital, Edinburgh

140 Once daily dosing of Tigecycline to facilitate outpatient parenteral antibiotic therapy (OPAT)Hui Chin1, Stephen Hughes2, Katie Heard2, Nabeela Mughal2,3,4, Luke Moore2,3,4

1University College London. 2Chelsea & Westminster NHS Hospitals, London. 3North West London Pathology at Imperial College Healthcare NHS Trust, London. 4National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London

141 Transmission of a new Klebsiella pneumoniae CG 258 with dual carbapenemases (KPC and OXA48) via flexible gastroscopeSurabhi Taori, Jeevani Kumarage, Kirstin KhonyongwaKing’s College Hospital NHS Foundation Trust, London

142 Cost of controlling a Candida auris outbreak in the UKSurabhi Taori, Iain Hayden, Kirstin Khonyongwa, Nergish DesaiKing’s College Hospital NHS Foundation Trust, London

143 Avoiding readmissions from OPAT: how old is too old?Nicholas Norton1, Elinor Moore2, Sian Coggle2

1Cambridge, 2Addenbrooke’s Hospital, Cambridge

144 Assessing the safety profile and cost-effectiveness of outpatient parenteral antimicrobial therapy (OPAT) for upper limb cellulitis in a tertiary referral Plastic Surgery CentreTanmay Kanitkar1,2, Katie Heard1, Dinesh Aggarwal2,1, Nabeela Mughal3,2,1, Luke Moore3,2,1

1Chelsea & Westminster NHS Foundation Trust, London. 2Imperial College Healthcare NHS Trust, London. 3Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London

145 Impact and efficiency of microbiologist-attendance at multidisciplinary team meetings and dedicated antimicrobial advice ward rounds within a hospital antimicrobial stewardship programmeAshley Whittington, Surjo De, Preet Panesar, Stephen Morris-JonesUniversity College London Hospitals

146 Rapid access Infectious Diseases Clinic at the Royal Victoria Infirmary Hospital, NewcastleVictoria Parris, Ewan HunterRoyal Victoria Infirmary, Newcastle

147 Spatial dynamics of ground-level malaria prevention; tackling severe paediatric malaria in Sierra Leone through motorcycle mapping and community empowermentEdward Monk1,2, Ka-Ping Yee3, Rupert Allan3, Ivan Gayton3

1Manchester University NHS Foundation Trust. 2Nixon Memorial Methodist Hospital, Segbwema, Sierra Leone. 3Missing Maps, London

148 Hospital-associated influenza transmission and its management in a UK teaching hospitalBen Warne1, Mark Reacher2, Lucy Reeve2, Iain Roddick2, David Williams3, Monica Galiano3, Nicholas Jones1, Kyriaki Ranellou1, Silvana Christou1, Callum Wright1, Ashley Popay2, Clare Sander1, Maria Zambon3, Hamid Jalal11Cambridge University Hospitals NHS Foundation Trust. 2Field Service, National Infection Service, Public Health England, Cambridge. 3National Infection Service, Public Health England, London

143 Avoiding readmissions from OPAT: how old is too old? Nicholas Norton, Elinor Moore, Sian Coggle Addenbrooke’s Hospital, Cambridge

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149 Audit of the effectiveness of clinical advice provided for patients with bloodstream infection at a District General HospitalMartha Purcell1, Bruce Stewart1,2

1Surrey and Sussex Healthcare NHS Trust, Redhill. 2Frontier Pathology NHS Partnership, Redhill

150 The impact of the Antimicrobial Stewardship Team on facilitating discharge via referral to the outpatient parenteral antimicrobial therapy (OPAT) serviceGagandeep GohlarFarhana Butt, London

151 Infection control lessons learnt due to cross infection with an extremely-drug resistant Acinetobacter in a modern intensive care unitKirsten MacGregor1, Fiona Hammond2, Samantha Matthews2, Elizabeth Darley1

1Severn Pathology Infection Sciences, Bristol. 2Infection Prevention and Control, North Bristol NHS Trust

152 Efficacy of teicoplanin in the outpatient parenteral antibiotic therapy (OPAT) settingHelena Wickham1, Hannah Dabrowski1, Michael Marks1,2, Jon Underwood1, Surjo De3, Sarah Logan1, Gabriele Pollara1,4

1Infection, University College London Hospitals. 2Clinical Research, London School of Hygiene and Tropical Medicine. 3Clinical Microbiology, University College London Hospitals, 4Infection & Immunity, University College London

153 The use of outpatient parenteral antimicrobial therapy in patients with non-cystic fibrosis bronchiectasis: a retrospective and prospective auditRory KennedyUniveristy of Manchester, University of Plymouth

154 Structured collaborative multi-disciplinary IPC approach to reduce healthcare associated (HCAI) methicillin sensitive Staphylococcus aureus (MSSA) bloodstream infectionHloniphani Mpofu, Julie SamuelThe Newcastle Upon Tyne Hospitals NHS Foundation Trust

155 Are current infection control and prevention methods effective in controlling transmission of Clostridium difficile infection in the inpatient population of a large teaching hospital? Using ribotyping to assess risk of patient to patient cross contaminationFindlay Lowson1,2, Susan Gould1, Tim Neal3, Mike Beadsworth1

1Tropical and Infectious Diseases, Royal Liverpool and Broadgreen University Hospital Trust. 2University of Liverpool. 3Royal Liverpool and Broadgreen University Hospital Trust

156 Lessons learnt from a prolonged ventilation failure in a containment level 3 Mycobacterial Reference LaboratoryPretin Davda, Grace E Smith, Priti Rathod, Esther RobinsonPublic Health England, Birmingham

157 Endocarditis in the 21st century: what, where and how?Anda SamsonHull & East Yorkshire Hospitals NHS Trust

158 A retrospective review of 15 patients treated for malignant otitis externa in an OPAT setting in 2016-2017Tamara Mitchell, Katharine Cartwright, Elisabeth RidgwaySheffield Teaching Hospitals

159 Quality improvement: improving adherence to guidelines for urinary legionella antigen testing in a large teaching hospitalFrancesca Knapper, Susan Mcculloch, Mahableshwar AlburSouthmead Hospital, North Bristol NHS Trust

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149 Audit of the effectiveness of clinical advice provided for patients with bloodstream infection at a District General HospitalMartha Purcell1, Bruce Stewart1,2

1Surrey and Sussex Healthcare NHS Trust, Redhill. 2Frontier Pathology NHS Partnership, Redhill

150 The impact of the Antimicrobial Stewardship Team on facilitating discharge via referral to the outpatient parenteral antimicrobial therapy (OPAT) serviceGagandeep GohlarFarhana Butt, London

151 Infection control lessons learnt due to cross infection with an extremely-drug resistant Acinetobacter in a modern intensive care unitKirsten MacGregor1, Fiona Hammond2, Samantha Matthews2, Elizabeth Darley1

1Severn Pathology Infection Sciences, Bristol. 2Infection Prevention and Control, North Bristol NHS Trust

152 Efficacy of teicoplanin in the outpatient parenteral antibiotic therapy (OPAT) settingHelena Wickham1, Hannah Dabrowski1, Michael Marks1,2, Jon Underwood1, Surjo De3, Sarah Logan1, Gabriele Pollara1,4

1Infection, University College London Hospitals. 2Clinical Research, London School of Hygiene and Tropical Medicine. 3Clinical Microbiology, University College London Hospitals, 4Infection & Immunity, University College London

153 The use of outpatient parenteral antimicrobial therapy in patients with non-cystic fibrosis bronchiectasis: a retrospective and prospective auditRory KennedyUniveristy of Manchester, University of Plymouth

154 Structured collaborative multi-disciplinary IPC approach to reduce healthcare associated (HCAI) methicillin sensitive Staphylococcus aureus (MSSA) bloodstream infectionHloniphani Mpofu, Julie SamuelThe Newcastle Upon Tyne Hospitals NHS Foundation Trust

155 Are current infection control and prevention methods effective in controlling transmission of Clostridium difficile infection in the inpatient population of a large teaching hospital? Using ribotyping to assess risk of patient to patient cross contaminationFindlay Lowson1,2, Susan Gould1, Tim Neal3, Mike Beadsworth1

1Tropical and Infectious Diseases, Royal Liverpool and Broadgreen University Hospital Trust. 2University of Liverpool. 3Royal Liverpool and Broadgreen University Hospital Trust

156 Lessons learnt from a prolonged ventilation failure in a containment level 3 Mycobacterial Reference LaboratoryPretin Davda, Grace E Smith, Priti Rathod, Esther RobinsonPublic Health England, Birmingham

157 Endocarditis in the 21st century: what, where and how?Anda SamsonHull & East Yorkshire Hospitals NHS Trust

158 A retrospective review of 15 patients treated for malignant otitis externa in an OPAT setting in 2016-2017Tamara Mitchell, Katharine Cartwright, Elisabeth RidgwaySheffield Teaching Hospitals

159 Quality improvement: improving adherence to guidelines for urinary legionella antigen testing in a large teaching hospitalFrancesca Knapper, Susan Mcculloch, Mahableshwar AlburSouthmead Hospital, North Bristol NHS Trust

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160 Monkeypox outbreak in Blackpool: clinical presentation, contact surveillance, post-exposure prophylaxis and outcomesPeter Flegg1, Ruth Palmer1, Sharon Mawdsley1, Susan Richardson1, Susan Houldsworth1, Nick Harper1, Meera Chand2, Nick Phin2

1Blackpool Teaching Hospitals NHS Trust, 2Public Health England, London

DIAGNOSTICS161 Comparison of four commercial rapid tests for the identification of carbapenamase enzyme

activityFiona Shaw, Chris Gerrard, James CargillAlder Hey Children’s Hospital, Liverpool

162 Verification of an existing blood culture incubation system when moving to a new laboratoryChris Gerrard, James CargillAlder Hey Children’s Hospital, Liverpool

163 The AdvanDx Staphylococcus QuickFISH test for the differentiation of Staphylococcus aureus and coagulase-negative staphylococci from positive blood culturesTeresa Barton, Kate Ball, Susie Batley, Pamela Hulme, Jane Johnson, Jessica Jones, Jane McGrane, Norma Thompson, Chris Gerrard, James CargillAlder Hey Children’s Hospital, Liverpool

164 Introducing the FilmArray Meningitis/Encephalitis panel to a specialist paediatric hospital: preclinical verification testing and unexpected findingsFiona Shaw, James CargillAlder Hey Children’s Hospital, Liverpool

165 Introducing the FilmArray Meningitis/Encephalitis panel to a specialist paediatric hospital: initial clinical introduction and lessons learntJames CargillAlder Hey Children’s Hospital, Liverpool

166 Introducing the FilmArray Meningitis/Encephalitis panel to a specialist paediatric hospital: sensitivity and specificity in the diagnosis or exclusion of paediatric meningitis and encephalitisJames CargillAlder Hey Children’s Hospital, Liverpool

167 Introducing the FilmArray Meningitis/Encephalitis panel to a specialist paediatric hospital: does the introduction of a rapid test affect the length of stay or sample quality?James CargillAlder Hey Children’s Hospital, Liverpool

168 A prospective evaluation of the clinical impact of Unyvero multiplex PCR in blood stream infectionsThomas Smith, Gosia Poznalska, Aiden Plant, Stephanie Murdoch, Cressida AucklandRoyal Devon & Exeter NHS Foundation Trust

169 A retrospective audit of the blood culture contamination rate at Southend University Hospital NHS Foundation TrustRachel Davies-Foote,JohnDay,JosephineElfickSouthend University Hospital NHS Foundation Trust

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160 Monkeypox outbreak in Blackpool: clinical presentation, contact surveillance, post-exposure prophylaxis and outcomesPeter Flegg1, Ruth Palmer1, Sharon Mawdsley1, Susan Richardson1, Susan Houldsworth1, Nick Harper1, Meera Chand2, Nick Phin2

1Blackpool Teaching Hospitals NHS Trust, 2Public Health England, London

DIAGNOSTICS161 Comparison of four commercial rapid tests for the identification of carbapenamase enzyme

activityFiona Shaw, Chris Gerrard, James CargillAlder Hey Children’s Hospital, Liverpool

162 Verification of an existing blood culture incubation system when moving to a new laboratoryChris Gerrard, James CargillAlder Hey Children’s Hospital, Liverpool

163 The AdvanDx Staphylococcus QuickFISH test for the differentiation of Staphylococcus aureus and coagulase-negative staphylococci from positive blood culturesTeresa Barton, Kate Ball, Susie Batley, Pamela Hulme, Jane Johnson, Jessica Jones, Jane McGrane, Norma Thompson, Chris Gerrard, James CargillAlder Hey Children’s Hospital, Liverpool

164 Introducing the FilmArray Meningitis/Encephalitis panel to a specialist paediatric hospital: preclinical verification testing and unexpected findingsFiona Shaw, James CargillAlder Hey Children’s Hospital, Liverpool

165 Introducing the FilmArray Meningitis/Encephalitis panel to a specialist paediatric hospital: initial clinical introduction and lessons learntJames CargillAlder Hey Children’s Hospital, Liverpool

166 Introducing the FilmArray Meningitis/Encephalitis panel to a specialist paediatric hospital: sensitivity and specificity in the diagnosis or exclusion of paediatric meningitis and encephalitisJames CargillAlder Hey Children’s Hospital, Liverpool

167 Introducing the FilmArray Meningitis/Encephalitis panel to a specialist paediatric hospital: does the introduction of a rapid test affect the length of stay or sample quality?James CargillAlder Hey Children’s Hospital, Liverpool

168 A prospective evaluation of the clinical impact of Unyvero multiplex PCR in blood stream infectionsThomas Smith, Gosia Poznalska, Aiden Plant, Stephanie Murdoch, Cressida AucklandRoyal Devon & Exeter NHS Foundation Trust

169 A retrospective audit of the blood culture contamination rate at Southend University Hospital NHS Foundation TrustRachel Davies-Foote,JohnDay,JosephineElfickSouthend University Hospital NHS Foundation Trust

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170 Predictive value of urinary interleukins (IL-6 and IL-8) for differentiating between asymptomatic and symptomatic bacteriuria in elderly patientsFenella Halstead1,2, Claire Williams3, Helena Ogbonna1, Emily Rousham4, Jon Hazeldine1,5, Beryl Oppenheim1

1NIHR Surgical Reconstruction and Microbiology Research Centre, Queen Elizabeth Hospital, Birmingham. 2University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital. 3Birmingham Community Healthcare Trust. 4School of Sport, Exercise and Health Sciences, Loughborough University. 5Institute of Inflammation and Ageing (IIA), University of Birmingham Research Laboratories, Queen Elizabeth Hospital

171 A review of the use of 16S rDNA PCR results as a diagnostic and stewardship tool at Severn Pathology servicesGeorgina Beckley, Ian Head, Alasdair MacgowanSouthmead Hospital, Bristol

172 Analysis of blood culture sampling practice and detection rates within Brighton and Sussex University Hospitals TrustSimon Stoneham1,2, William Schilling1, Alberto San Francisco Ramos1, Matthew Longbone1, Martin Llewelyn1,2

1Microbiology and Infection, Royal Sussex County Hospital, Brighton, 2Global Health and Infection, Brighton and Sussex Medical School

173 Comparison between the Vitek2 yeast identification and antifungal susceptibility testing with the reference laboratory methodsSahar Eldirdiri1, William Olver2

1Microbiology, Ninewells Hospital, Dundee. 2Ninewells Hospital, Dundee

174 How can fast identification & antimicrobial susceptibility testing improve patient care and antibiotics stewardship in critically ill patients?Houdini H.T. Wu, Steve Wilson, Li Xu-McCrae, Paul Connor, Ahmed Hussain, Karen Reynolds, Abid HussainPHE Public Health Laboratory Birmingham

175 Thermonuclease test accuracy is significantly reduced in methicillin-resistant Staphylococcus aureus isolatesBenjamin Canning1, Iskandar Mohamed1, Nimal Wickramasinghe2, Jonathan Swindells1, Matthew O’Shea3

1Sandwell and West Birmingham Hospitals NHS Trust. 2University Hospitals Birmingham NHS Foundation Trust. 3University of Birmingham

176 Quality improvement project: reducing the inappropriate use of urine dipsticks in the management of suspected urinary tract infectionMaurice Madeo1, Bethan Stoddart2, Linda Barker3, Jayne Girdham3, Joanne Jones3, Marion Hewis3, Noelle Williams3

1Deputy Director Infection Prevention and Control, North Lincolnshire and Goole NHS Foundation Trust. 2Lead Consultant Microbiologist, Path Links, North Lincolnshire and Goole NHS Foundation Trust. 3Infection Prevention and Control, North Lincolnshire and Goole NHS Foundation Trust

177 The impact of improving Influenza testing turnaround times on hospital flows and length of stayMaurice Madeo1, Lyn Clare2, Bethan Stoddart3

1Deputy Director Infection Prevention and Control, North Lincolnshire and Goole NHS Foundation Trust. 2Infection Prevention and Control Data Analyst, North Lincolnshire and Goole NHS Foundation Trust. 3Lead Consultant Microbiologist, Path Links, North Lincolnshire and Goole NHS Foundation Trust

178 The clinical impact of early MALDI-TOF identification of bacteria from positive blood culturesPhilip House, Gemma WinzorHeartlands Hospital, Birmingham

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170 Predictive value of urinary interleukins (IL-6 and IL-8) for differentiating between asymptomatic and symptomatic bacteriuria in elderly patientsFenella Halstead1,2, Claire Williams3, Helena Ogbonna1, Emily Rousham4, Jon Hazeldine1,5, Beryl Oppenheim1

1NIHR Surgical Reconstruction and Microbiology Research Centre, Queen Elizabeth Hospital, Birmingham. 2University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital. 3Birmingham Community Healthcare Trust. 4School of Sport, Exercise and Health Sciences, Loughborough University. 5Institute of Inflammation and Ageing (IIA), University of Birmingham Research Laboratories, Queen Elizabeth Hospital

171 A review of the use of 16S rDNA PCR results as a diagnostic and stewardship tool at Severn Pathology servicesGeorgina Beckley, Ian Head, Alasdair MacgowanSouthmead Hospital, Bristol

172 Analysis of blood culture sampling practice and detection rates within Brighton and Sussex University Hospitals TrustSimon Stoneham1,2, William Schilling1, Alberto San Francisco Ramos1, Matthew Longbone1, Martin Llewelyn1,2

1Microbiology and Infection, Royal Sussex County Hospital, Brighton, 2Global Health and Infection, Brighton and Sussex Medical School

173 Comparison between the Vitek2 yeast identification and antifungal susceptibility testing with the reference laboratory methodsSahar Eldirdiri1, William Olver2

1Microbiology, Ninewells Hospital, Dundee. 2Ninewells Hospital, Dundee

174 How can fast identification & antimicrobial susceptibility testing improve patient care and antibiotics stewardship in critically ill patients?Houdini H.T. Wu, Steve Wilson, Li Xu-McCrae, Paul Connor, Ahmed Hussain, Karen Reynolds, Abid HussainPHE Public Health Laboratory Birmingham

175 Thermonuclease test accuracy is significantly reduced in methicillin-resistant Staphylococcus aureus isolatesBenjamin Canning1, Iskandar Mohamed1, Nimal Wickramasinghe2, Jonathan Swindells1, Matthew O’Shea3

1Sandwell and West Birmingham Hospitals NHS Trust. 2University Hospitals Birmingham NHS Foundation Trust. 3University of Birmingham

176 Quality improvement project: reducing the inappropriate use of urine dipsticks in the management of suspected urinary tract infectionMaurice Madeo1, Bethan Stoddart2, Linda Barker3, Jayne Girdham3, Joanne Jones3, Marion Hewis3, Noelle Williams3

1Deputy Director Infection Prevention and Control, North Lincolnshire and Goole NHS Foundation Trust. 2Lead Consultant Microbiologist, Path Links, North Lincolnshire and Goole NHS Foundation Trust. 3Infection Prevention and Control, North Lincolnshire and Goole NHS Foundation Trust

177 The impact of improving Influenza testing turnaround times on hospital flows and length of stayMaurice Madeo1, Lyn Clare2, Bethan Stoddart3

1Deputy Director Infection Prevention and Control, North Lincolnshire and Goole NHS Foundation Trust. 2Infection Prevention and Control Data Analyst, North Lincolnshire and Goole NHS Foundation Trust. 3Lead Consultant Microbiologist, Path Links, North Lincolnshire and Goole NHS Foundation Trust

178 The clinical impact of early MALDI-TOF identification of bacteria from positive blood culturesPhilip House, Gemma WinzorHeartlands Hospital, Birmingham

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179 Review of the clinical significance of the aerobic blood culture bottle since its addition to the blood culture service in Newcastle HospitalsRichard Capstick, Angela Geering, Jennifer Collins, Ali RobbNewcastle upon Tyne

180 Poor sensitivity of the qSOFA assessment when deployed as a standalone screening tool for sepsis in adult inpatients at a large District General HospitalRobert Gray, Hala Kandil, Moira Surridge, Tejal VaghelaWest Hertfordshire Hospitals NHS Trust, Watford

181 Point of care influenza testing has not led to a increase in discharge within 24 hours of Influenza positive patientsMilo Cullinan, Yusri Taha, Shirelle Burton-FanningNewcastle-upon-Tyne Hospital Trusts

182 Diagnostic stewardship in practice - optimising urine testingIla Aggarwal, John Shone, Anne SermanNHS Tayside, Dundee

183 Evaluation of the Alere BinaxNOW® pneumococcoal urinary antigen test in community acquired pneumonia with S. pneumoniae bacteraemia. Time for a change?Stephen Hughes1, Scott Pallett1, Nabeela Mughal1,2, Luke Moore1,2

1Chelsea & Westminster NHS Hospitals, London. 2National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London

184 Fungal biomarker turn-around-time (TAT) and antifungal stewardship: how long is too long?Clare Logan1, Jonathan Youngs1, Hassan Al-Ghusein1, Silke Schelenz2, Tihana Bicanic1

1St George’s Hospital, London. 2Royal Brompton Hospital, London

185 The impact of routine molecular point-of-care testing for gastrointestinal pathogens in adults hospitalised with suspected gastroenteritis: results of a pragmatic randomised controlled trial (GastroPOC)Kate Beard1, Ahalya Malachira2, Nathan Brendish1,2, Fraser Cummings3, Marcus Gwiggner3, Tristan Clark4,2,5

1University of Southampton. 2Infection, University Hospital Southampton NHS Foundation Trust. 3Gastroenterology, University Hospital Southampton NHS Foundation Trust. 4Academic Unit of Clinical and Experimental Sciences, University of Southampton. 5NIHR Post-Doctoral Fellowship Programme, Southampton

186 Clinical utility of the beta-D-glucan assay in general medical and surgical patientsShivani Singh1, Nabeela Mughal2,3, Luke Moore 2,3,4

1Imperial College School of Medicine, London. 2Chelsea & Westminster NHS Foundation Trust, London. 3North West London Pathology at Imperial College Healthcare NHS Trust, London. 4National Institute for Health Research Health Protection Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London

187 Evaluation of acute phase reactants (white blood cell count, procalcitonin and C-reactive protein) in medical admissions - a tertiary hospital experiencePete Dayananda, Nickh Uppal, Joanna Allen, Graham SuttonLeeds Teaching Hospitals NHS Trust

188 5 years of MERS-CoV testing experience in a regional virology centreBozena Poller1, Anne Tunbridge2, Cariad Evans1

1Virology, Sheffield Teaching Hospitals NHS Foundation Trust. 2Infectious Diseases, Sheffield Teaching Hospitals NHS Foundation Trust

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TB AND OTHER MYCOBACTERIA189 It’s all in the name (species)

Julie SamuelNewcastle upon Tyne Hospitals NHS Foundation Trust

190 Skin infection with Mycobacterium szulgai: a successful but complicated treatmentJemima Horsley Downie1, Han Davidson2, Ali Robb1, Suren Kanagasundaram1, Ewan Hunter1

1Newcastle upon Tyne Hospitals NHS Foundation Trust. 2Newcastle upon Tyne Hospitals Pharmacy Department

191 Using the UK multi-drug resistant tuberculosis (MDR-TB) monitoring guideline to improve the monitoring of patients in the communityPhoebe Cross1, Toby Capstick1, Amy Robinson2, Hugh McGann1

1Leeds Teaching Hospitals. 2Bradford Teaching Hospitals

192 A vole lot of problemsAnna Wild, Louise Berry, Pradhib VenkatesanInfectious Diseases, Nottingham City Hospital

193 TB outbreaks and contact tracing in congregate settings – a retrospective analysis in a large ethnically diverse urban environment – Birmingham UKDarryl Braganza Menezes1, Hanna Kaur2, Tom Marshall1, Emmanouil Tranos1, Gemma Hawthorne3, Pretin Davda3, Martin Dedicoat3

1University of Birmingham. 2Birmingham Chest Clinic. 3Heartlands Hospital, Birmingham

194 To treat or not to treatEve Hamilton1, Simon Howard2, Edmund Ong1

1RVI, Newcastle upon Tyne, 2Public Health, North East

195 Experience of screening for latent TB infection (LTBI) in high risk community populations using extended testing eligibility criteriaNatasha Ratnaraja1, Pavanjit Jheeta2, Tracy Morrod2

1University Hospitals Coventry and Warwickshire. 2Sandwell and West Birmingham Hospitals`

196 The use of Interferon Gamma Release Assay (IGRA) testing for latent Mycobacterium tuberculosis prior to commencing immune-modulating drugs and the subsequent management of identified cases of latent M. tuberculosisAlice Maxwell, Emmanuel Nsutebu, Geraint DaviesRoyal Liverpool and Broadgreen University Hospitals NHS Trust

197 Mycobacterium abscessus; lessons learnt from a complex caseFrancesca Knapper, Alexander May, Kirsten MacGregor, Izak Heys, Charlotte HallSouthmead Hospital, North Bristol NHS Trust