GWAS: an Exemplar of the Genome Era? Whole-genome ... · O LP (a) levels O LpPLA(2) activity and...

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GWAS: an Exemplar of the Genome Era? Whole-genome association approach to common disease: the 2002 view: $10,000,000,000 for each disease the 2007 view: $800,000 for each disease

Transcript of GWAS: an Exemplar of the Genome Era? Whole-genome ... · O LP (a) levels O LpPLA(2) activity and...

Page 1: GWAS: an Exemplar of the Genome Era? Whole-genome ... · O LP (a) levels O LpPLA(2) activity and mass Lung cancer O Magnesium levels Major mood disorders Malaria O Male pattern baldness

GWAS: an Exemplar of the Genome Era?

Whole-genome association approach to common disease:

the 2002 view: $10,000,000,000 for each disease

the 2007 view: $800,000 for each disease

Page 2: GWAS: an Exemplar of the Genome Era? Whole-genome ... · O LP (a) levels O LpPLA(2) activity and mass Lung cancer O Magnesium levels Major mood disorders Malaria O Male pattern baldness
Page 3: GWAS: an Exemplar of the Genome Era? Whole-genome ... · O LP (a) levels O LpPLA(2) activity and mass Lung cancer O Magnesium levels Major mood disorders Malaria O Male pattern baldness
Page 4: GWAS: an Exemplar of the Genome Era? Whole-genome ... · O LP (a) levels O LpPLA(2) activity and mass Lung cancer O Magnesium levels Major mood disorders Malaria O Male pattern baldness
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Page 6: GWAS: an Exemplar of the Genome Era? Whole-genome ... · O LP (a) levels O LpPLA(2) activity and mass Lung cancer O Magnesium levels Major mood disorders Malaria O Male pattern baldness
Page 7: GWAS: an Exemplar of the Genome Era? Whole-genome ... · O LP (a) levels O LpPLA(2) activity and mass Lung cancer O Magnesium levels Major mood disorders Malaria O Male pattern baldness
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The Marriage Gene???

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The Future