Guptill MicMac Connection

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    8, 2000 Statement.

    Date: Fri, 24 Dec 1999 12:44:05 -0400From: "BaiTY & Barb G.llptill" - g u p t i l l b ( ~ : n b n .1: b.ca>To: Clmc"ka Jet obI "t.ub.cd>of the statement my f

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    Subject: New II cousins"Date: Fri, 05 Mar 1999 19:3313 +0000From; ART ]vIACKAY

    n : ART MACKL\Y STUDIOSTo ; "Kosky, Kem' Guptill"

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    Thomas Cheney - mystery lady #1. There appears to be noBizabeth being from other Cheney families on Grand Manall.ver, I ran across a reference to her coming from Indian Island, an

    post close to Deer Island, Campobello and Eastport~ c o r d s include her siblings but I cannot find the names of herI am seeking more information on her family

    (Susanne Bancroft) - mystef'j lady #2 - The census of 1851 lists(18 years of age). Judson L15 years at this time. They later married. Susan also is not listed

    and Ivlanan Bancroft families. One note suggestson Susan as well

    my mother. She is 89 this spring andghted when I told her about your web. Our family myth "vas that the Gubtailstch!!! She thought that she liked the idea of Wales nevertheless Iam to deliver forthwith!

    Rose Getchell As a matter of interest, Marg's family cameof the first settlers at St. Stephen, N.B. He moved frommoves are very similar to those of the

    history ... one of her relatives was the guideAmold when he went up the Kennebec to attack Quebec in

    ... the tradition!

    add me to your "cousin chart". Yes I would love to'Ie aI think that I might have some Grand 1vlanan infonnation which would. Unfortunately, I haven't had time to digitize it. I wouldfa.x or mail copies of what I have if you would like. Myhas tons of material which I am trying to get access to and Iit all together sometime.

    ks for \'vriting. I hope that this is all of interest to you.

    lvfacKay Studios

    mailto:[email protected]:[email protected]
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    Genealogy - Ancestry.com http://dna.ancestry.com/leamMore.aspxJsessionid=5F53EBC4A58

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    Usemame Password (forgot')L an.ome resultsAdd M.tDN8 results

    F Q< Answers to [reQu.e.ntl as.kedFinding genetic cousins Q.U".stijJIlS

    By comparing your DNA Ancestry test results with others, you can determine to what extent you arerelated. For example, the more closely your result set matches another's, the narrower the range ofgenerations between the two of you and your common ancestor. SEE WHAT YOUR DNATEST MIGHT LOOK LIKE,

    t, t ; , See Sample Resultst Review DNA.?.!iy1\..CV 91jj;y, ,". ......

    As the DNA Ancestry database grows, we will automatically compare your result against each new entry.I f a close match is found, you will receive an e-mail with a link to a page that describes how your two testresuits match. You can now begin communicating with your genetic cousin using Ancestry.com'sConnection Service as the first step towards comparing the genealogies of your two families.Discover ancient ancestryIn addition to finding genetic cousins, your DNA test can also reveal your ancient origins. Beginning over170,000 years ago, our ancient human ancestors migrated out of Africa and began their slow and steadyspread across the continents. Over time as these ancestors spread throughout the world and adapted totheir new surroundings and environments, tileir DNA diversified and they became genetically distinct fromone another. Today, these differences can be traced through DNA and provide insights on how yourancient ancestors migrated and diversified into distinct populations.

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    Genealogy - Ancestry.com http://doa.ancestry.comllearnMore.aspxJsessionid=5F53EBC4A58

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    What 1S DNA and GenealogyAll humans have 23 pairs of chromosomes, including a pair of sex chromosomes, known as "X" and "Y".Males have both an X- and a Y-chromosome (with the Y-chromosome inherited from the father) whilefemales have two X-chromosomes (one X-chromosome inherited from each parent.) Genetic Genealogyis interested in heritage markers or the area of the chromosome which reveals family relatedness.Father-to-SonBecause the Y-chromosome is passed essentially unchanged from father-to-son, it provides geneticgenealogists with a powerful tool for tracing a paternal lineage. Specific portions of the Y-chromosomeare analyzed and compared against other partidpants' Y results to determine the relatedness betweenthe two participants.Mother-to-ChildSince both parents contribute X-chromosomes to their daughters, a different source of DNA must be usedto trace the maternal line. Mitochondrial DNA (mtDNA) is inherited by both male and female childrenexclUsively from their mothers and provides insight into one's maternal lineage. (!,-earn m re aboutmitochondrial D ~ c

    What DNA Ancestry Testing Cannot DoThe type of testing performed by DNA Ancestry is limited to areas of DNA that have the greatestapplication to genealogy which reveal insight into family relatedness. The portion of DNA tested is withinthe non-coding regions and do not prOVide distinguishing information about an individual such as haircolor.While DNA testing in general has a promising future as a tool for predicting one's chances for developingdisease such as diabetes, Alzheimer's, and cancer; DNA Ancestry does not perform medical diagnostictesting on any of its DNA samples.A common application of DNA testing is in determining the paternity of a child for custody or inheritance.Results of a DNA Ancestry test can definitively disprove a genetic relation. A large number of mismatchesbetween two test results reflects that the two participants are not directly related. A 100% match, on theother hand, cannot be used as legal proof of paternity, but can serve as a strong indication.

    Privacy BackDNA Ancestry protects your privacy by allOWing you to make your DNA results anonymous. Doing sohides your Ancestry .com username, but allows your DNA results to still be matched with others in theDNA Ancestry database. So even if you have chosen to keep your username hidden, you can still discovergenetic cousins and, if the match is close enough, contact them safely and anonymously.Connection ServiceYour privacy is also protected by using Ancestry.com's Connection Service to contact other DNAparticipants. The Connection Service allows you to send an e-mail to a potential genetic relative withoutrevealing your own e-mai l address. Instead, the message is sent through Ancestry .com and the systemtransfers the message to your e-mail address without revealing your actual address. Replies can also bemade through the Connection Service until you feel you wish to make direct e-mail contact with the otherparty.

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    http://dna.ancestry.comlJeamMore.aspxjsesslomd=jr)3.l:J:KAAjlSc Genealogy - Ancestry.com

    How do I collect a sample?Collecting a DNA sample is easy and painless. Simply swab the inside of your mouth to collect cheek cellsand return the swabs to DNA Ancestry. Within a few weeks, your results will be ready. No blood sampleneeded'Shortly after you confirm your order, you'll receive an e-mail indicating that your test kit has been sent.In a few days, you should receive your personalized kit which contains:

    Instructi ons for collecting a DNA sample A collection envelope to fill out prior to enclosing your swabs A sterile pack containing three synthetic DNA collection swabs Pre-paid mailing envelope addressed to DNA AncestryStep 1 - Prepare to Collect DNA SampleIncluded in each DNA Collection Kit, is a form printed on the Collection Envelope to be completed by theparticipant (person prOViding the DNA sample.)Before you collect the sample, make sure you have waited at least 30 minutes from your last meal orsnack to help reduce sample contamination.Step 2 - Collect DNA Sample

    Open the Swab Packet and remove one swab. Leave the other swabs in the sterile package untilready for use. Holding only the stick portion (do not touch the swab area), rub the swab up and down the insideleft wall of your mouth. Vigorously scrape the inner left cheek using a vertical, up-and-downmotion. Rotate the swab while scraping the inner cheek surface. Do this for a minimum of 30seconds. Place swab directly into the Collection Envelope. Do NOT put it back into the Swab Packet. Do NOTtouch the swab area to any other surface. Repeat steps A and B with the remaining two swabs in the Swab Packet, swabbing the inner rightcheek with one of the swabs and the inside front of the mouth with the other. This kit is for one individual only. The same person must use all three swabs. Do NOT return samples from more than one person in a single envelope. We recommend leaving the Collection Envelope open for about 30 minutes after collection to allowthe samples to dry before sealing the envelope.

    Step 3 - Mail th e DNA Collection Ki tOnce the swabs have dried, carefully place them into the Collection Envelope and enclose this envelopeinto the pre-addressed mailing envelope. If you are mailing from outside of the United States or Canada,please place the appropriate postage on the envelope.You will receive an e-mail notification when the lab receives your DNA sample, and again when your DNAresults are available. It only takes a few weeks for the lab to process your DNA and make your resultsavailable.Once your test results have been entered into the system, DNA Ancestry will continually look for peoplewho have similar DNA results so that you might find your long lost genetic cousin.

    The Science Behind Genetic GenealogyThe follOWing sections prOVide an overview of the science behind DNA and genealogy. It will familiarizeyou with some of the technical terms commonly used in the field of genetic genealogy.DNA is found in every cell in your body except the red blood cell. It is located in the center of the cell in amembrane called the nucleus. DNA contains all the information necessary to coordinate the functions of your body from wiggling your toes to operating your heart. That's a lo t of information! A typical animalcell contains one meter of DNA. Written in a linear alphabet of four letters, the genetic information carriedin a human cell could fill a book of more than 500,000 pages' But how is that much information packaged?DNA is tightly wrapped in configurations known as Genes, which are the functional units of DNA. GenesprOVide provide the instructions for life. The human genome is estimated to contain 30,000 to 40,000genes.

    Only about 2% of the human genome contains genes; the remainder consists of non-coding regions,whose functions vary from proViding structure to the chromosome, to having no detectable purpose. It isthese non-coding segments that are being compared for genealogical purposes.Humans have a total of 46 chromosomes, which are grouped into pairs. Each of the 23 pairs consists of one chromosome from our mother and one from our father. In females the 23rd chromosome pairconsists of two X-chromosomes. Males, however, have an X-chromosome and a V-chromosome. It is,therefore, the V-chromosome (Yes) that determines the male gender. It is also the V-chromosome (Yes)that is one of the most useful chromosomes in genealogical studies. The Y-chromosome has the uniqueproperty of being passed virtually unchanged from generation to generation. This means that a man andall his sons will have the same, or similar, V-chromosome. likeWise, he will have the sameV-chromosome as his father and grandfather and so on. This gives the V-chromosome the uniqueproperty of following the surname, in most cases, which makes it a very valuable genealogical tool.In addition to DNA found within the nucleus of the cell, DNA can also be found in the mitochondria of thecell. The mitochondria is the power house of the cell. It is responsible for producing energy to perform allthe cellular functions. The mitochondrial DNA (mtDNA) follows the direct maternal line. Women pass theirmtDNA to all of their children, but then only the daughters will pass it on to the next generation.

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    Genealogy - Ancestry.com h t t p : / / d n a . a n c e s t r y . c o m i J e a r P M o r e . a s p x j s e s s i o n i d = 5 F 5 3 E H C 4 A 5 >

    DNA itself is a helical structure, similar to a ladder. The outside of the ladder is a sugar-phosphatebackbone and the rungs are made of paired nitrogenous bases. These bases come in four varieties:Adenine (A). Thiamine (T), Cytosine (C), and Guanine (G). A always pairs with T and C always pairs withG along the rungs of the ladder.The type of testing performed by DNA Ancestry is limited to areas of DNA that have the greatestapplication to genealogy which reveal insight into family relatedness. Heritage markers are within thenon-coding regions and do not provide distinguishing information about an individual such as hair color.Typically there are three m ain kinds of analysis performed fo r genealogical purposes: DNA sequencing,Single Nucleotide Polymorphism testing (SNPs), and Short Tandem Repeat testing (STRs).DNA Sequencing is the process of determining the exact base pai r sequence in a predete rmined section ofDNA. This technique is most often used in mitochondrial DNA (mtDNA) testing where the sequence ofhypervariable region I (HVR I) and hypervariable region II (HVR II ) is determined. This kind of analysis isuseful for direct maternal lineage testing or for maternal ancient ancestry typing.Single Nucleotide Polymorphisms (SNPs, pronounced "snips") are single base pair changes that occurinfrequently throughout the genome. SNP testing is available for mtDNA, and V-chromosome. This testingcan confirm an indiVidual's deep ancestral grouping or haplogroup. While not directl y genealogically(recent past) relevant, haplogroups are instead anthropological (ancient past) in nature. This type ofanalysis allows us to track the branching of haplogroups and subgroups from our original African homeand discover interesting facts about our own ancient ancestor's movements across time and geography.Short Tandem Repeats (STRs) are segments of DNA that repeat themselves, for example a GATAsequence repeated several times (GATA GATA GATA). Every individual has STR segments at specificlocations on the chromosome. The specific locations are referred to as Loci or Markers and are gene rallynoted as DYS###, for example DYS459. DYS indicates the location is on the V-chromosome at position459.While everyone has these repeated regions, the distinction between one individual and another is thenumber of times the segment repeats. For example, at a given locus or marker on the chromosome, oneindividual may have 12 GATA's, and another indiVidual may have only 10 GATA's. These numbers, 12 and10, are called alleles. It is the collection of alleles for an indiVidual at specific locations (loci) that make uphis or her unique DNA profile or haplotype. These profiles or haplotypes are used for identificationpurposes, to d etermine paternity, or to establish relatedness.

    Ancient Ancestry - HaptogroupsAbout HaplogroupsHumans began to diversify as they migrated out of Africa and populated the rest of the world, adapting tonew climates, diets, and liVing conditions. Over tens of thousands of years, these ancient populationsbecame isolated and their DNA changed until they became genetically distinct from one another. Thesedeep ancestral groupings are referred to today as MPL9.C-Ql!.P5. Through DNA testing, we can track thebranching of haplogroups and their SUbgroups from the original African home and thus discover interestingfacts about our own ancient ancestors' movements across time and geography. DNA Ancestry prOVides acomplime ntary haplogroup prediction with each V-chromosome or mtDNA test.Paternal Ancient AncestryYour Ychromosome haplogroup can provide an interesting glimpse into the deep ancestry of yourpaternal line. Every race of people indigenous to this earth is a member of a particular haplogroup. YourPaternal Ancient Ancestry (or Haplogroup) is predicted based on your Y-DNA results. You will receive thename of the haplogroup, a detailed description of the group, and a map showing how your ancientancestors migrated out of Africa over 100,000 years ago and split of f to populate the different regions ofthe world.Approximately 18 major paterna/line haplogroups exist, known as A through R and are subdivided intosubclades represented by numbers and subsequent subclades labeled with a lower case alphabeticcharacter, e.g. E, E3, E3a. Haplogroup R1b is the most common haplogroup in European populations. It isbelieved to have expanded throughout Europe 10-12 thousand years ago.Major V-chromosome Haplogroups include: Rib

    I B E3a E3b J

    Maternal Ancient AncestryMaternal ancient lineages or haplogroups can be subdivided into sub-lineages which are often regionallyor population specific. For example, haplogroup H accounts for about 50% of European populations. It isbelieved to have originated in the Near East approximately 23,000-28,000 years ago and expanded intoEurope about 20,000 years ago. DNA Ancestry examines mu ltiple regions of the mitochondrial DNA toprovide the most information possble about a maternal lineage. Participants can be either male orfemale.