Guidelines Development Group for Consolidated guidelines ...

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Guidelines Development Group for Consolidated guidelines on the management of latent tuberculosis infection. Disclaimer In order to enhance its management of conflicts of interest as well as strengthen public trust and transparency in connection with WHO meetings and activities involving the provision of technical/normative advice, the names and brief biographies of individuals (“Published Information”) being considered for participation in a WHO-convened Guideline Development Group are disclosed for public notice and comment. The Published Information is provided by the experts themselves and is the sole responsibility of the individuals concerned. WHO is not responsible for the accuracy, veracity and completeness of the Published Information provided. Furthermore, in no event will WHO be responsible or liable for damages in relation to the use of, and reliance upon, the Published Information. The comments received by WHO through the public notice and comment process are treated confidentially and their receipt will be acknowledged through a generic email notification to the sender. Comments brought to the attention of WHO through this process are an integral component of WHO’s conflict of interest assessment process and are carefully reviewed. WHO reserves the right to discuss information received through this process with the relevant expert and disclose to this expert the name and affiliation of the provider of such information. Upon review and assessment of the information received through this process, WHO, in its sole discretion, may take appropriate management action in accordance with its policies. Guideline Development Groups provide technical and/or normative advice and recommendations to WHO. Participation in a Guideline Development Group convened by WHO does not necessarily mean that the views expressed by the expert concerned are shared by WHO and/or represent the decisions or stated policy of WHO. The list of participating experts, a summary of relevant interests disclosed by such experts, and any appropriate mitigation measures taken by WHO relating to the management of conflicts of interests, will be reported publically in accordance with WHO policies.

Transcript of Guidelines Development Group for Consolidated guidelines ...

Page 1: Guidelines Development Group for Consolidated guidelines ...

Guidelines Development Group for Consolidated guidelines on the management of latent tuberculosis infection.

Disclaimer

In order to enhance its management of conflicts of interest as well as strengthen public trust and

transparency in connection with WHO meetings and activities involving the provision of

technical/normative advice, the names and brief biographies of individuals (“Published Information”)

being considered for participation in a WHO-convened Guideline Development Group are disclosed

for public notice and comment.

The Published Information is provided by the experts themselves and is the sole responsibility of the

individuals concerned. WHO is not responsible for the accuracy, veracity and completeness of the

Published Information provided. Furthermore, in no event will WHO be responsible or liable for

damages in relation to the use of, and reliance upon, the Published Information.

The comments received by WHO through the public notice and comment process are treated

confidentially and their receipt will be acknowledged through a generic email notification to the

sender. Comments brought to the attention of WHO through this process are an integral component of

WHO’s conflict of interest assessment process and are carefully reviewed. WHO reserves the right to

discuss information received through this process with the relevant expert and disclose to this expert

the name and affiliation of the provider of such information. Upon review and assessment of the

information received through this process, WHO, in its sole discretion, may take appropriate

management action in accordance with its policies.

Guideline Development Groups provide technical and/or normative advice and recommendations to

WHO. Participation in a Guideline Development Group convened by WHO does not necessarily

mean that the views expressed by the expert concerned are shared by WHO and/or represent the

decisions or stated policy of WHO.

The list of participating experts, a summary of relevant interests disclosed by such experts, and any

appropriate mitigation measures taken by WHO relating to the management of conflicts of interests,

will be reported publically in accordance with WHO policies.

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Biographies of members of the Guideline Development Group

Name: Mohammed Redha Al Lawati

Institutional affiliation(s): Consultant Physician

Former Head of National HIV/AIDS, TB & Leprosy Control Programs

Academic degrees: MBBS, MSc

City and country of primary residence: Muscat, Oman

Biography

Dr Mohammed Al Lawati was trained in Respiratory Medicine in Brompton Hospital London

and in Respiratory & HIV Medicine in St. Vincent’s Hospital and St. George’s Hospital

Sydney. After returning from his training, he played key role in developing Respiratory, HIV

and Tuberculosis Services in Oman. He currently serves as Consultant Physician in KIMS

Hospital Oman and until recently, as Head of National AIDS, TB and Leprosy Control

Programs in MOH, Oman. Dr Mohammed has participated in teaching of undergraduate

students and in 1999 was awarded as one of the best clinical tutors by Sultan Qaboos

University. He also actively participates in the training of doctors in management of Asthma,

HIV and Tuberculosis and has played pivotal role in forming National Guidelines for the

management of Tuberculosis, Asthma and HIV/AIDS. Dr Mohammed has published papers

in the national and International Journals on Tuberculosis and HIV/AIDS. He is the founding

member of Oman Respiratory Society and previously has served as its Vice President. He

served as member of Global Validation Advisory Committee of WHO, for Elimination of

Mother to Child Transmission of HIV infection.

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Name: Rolando A. Cedillos

Institutional affiliation(s): Chief of Infectious Diseases at Hospital Nacional Rosales and

Professor of Medicine at the University of El Salvador.

Academic degrees: M.D. MSc. DTM&H

City and country of primary residence: San Salvador,El Salvador

Biography

Born August 16, 1959 in San Salvador, El Salvador. Graduated as a Doctor in Medicine at

the University of El Salvador. Completed residency in Internal Medicine at Hospital Nacional

Rosales in El Salvador in 1996.

MSc in Infection & Health in the Tropics (Tropical Medicine & International Health) at the

London School of Hygiene & Tropical Medicine and Diploma in Tropical Medicine &

Hygiene from the Royal College of Physicians, United Kingdom in 1997.

Since 1998 Chief of Infectious Diseases at Hospital Nacional Rosales and Professor of

Medicine at the University of El Salvador.

Collaborator of the World Health Organization (WHO) and the Pan American Health

Organization (PAHO) in the clinical management of Tuberculosis and HIV.

Author and presenter of works on the natural history of HIV, access to retroviral treatment in

Central America and of the book “La Epidemia Invisible” Historias del SIDA en El Salvador

currently on translation as “The Invisible Epidemic” a Central American AIDS memoir.

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Name: Anna Marie Celina Garfin

Institutional affiliation(s): Infectious Diseases for Prevention and Control Division, Disease

Prevention and Control Bureau, Department of Health

Academic degrees: MD, MM

City and country of primary residence: Quezon City, Philippines

Biography

Since 1999 as a staff of the National Tuberculosis Control Program of the Department of

Health has been involved in the development of policies and guidelines, training modules,

manual of operations and standards in the implementation of the National TB Control

Program in the country. I was also involved in the formulation of the clinical practice

guidelines for the diagnosis, treatment, prevention and control of TB in adults and children

spearheaded by the Philippine Coalition against Tuberculosis and the various Professional

Medical Societies.

List of relevant outputs are the following: Manual of Procedures for the National

Tuberculosis Control Program, 4th

and 5th

edition (2005 and 2014), The Health Promotion

Handbook (2008) and various polices release as administrative orders for TB control Program

implementation.

Relevant trainings attended are the following: Training to Develop Consultancy Skills on

Programmatic Management of Drug-Resistant Tuberculosis in the Western Pacific Region by

WHO last December 3 to 7, 2012 in Manila, Philippines; Advance Course in TB Control

Management by Japan International Cooperation Agency last January 11, 2005 – February 5,

2005 at the Research Institute of TB, Japan Anti-TB Association; and the Field Epidemiology

Training Program of the Department of Health.

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Name: Padmapriyadarsini Chandrasekaran

Institutional affiliation(s): Deputy Director (Medical)

National Institute for Research in Tuberculosis

[Indian Council for Medical Research]

Mayor Sathyamoorthy Road, Chetput,

Chennai 600 031

Academic degrees: M.B.B.S; D.N.B; M.S. (CR)

City and country of primary residence : Chennai, India

Biography :

Dr. C. Padmapriyadarsini is a Clinician by training and is currently Deputy Director (medical)

in the Department of Clinical Research at the National Institute for Research in Tuberculosis

(NIRT) (formerly known as the Tuberculosis Research Centre), Chennai. She has a Short-

term Fellowship in HIV epidemiology from University of California, Los Angeles and a

Masters Degree in Clinical and Translational Research from Tufts University Boston, USA.

Over the last 15 years, she is involved in multiple clinical studies and trials involving

HIV and TB coinfected adults and children at NIRT. She is the Principle investigator of

multiple collaborative, multicentric projects, both at national and international level. She has

more than 45 publications in peer reviewed national and International journals and 3 book

chapters to her credit. She has been involved in framing National Guidelines for

Management of Extra-pulmonary TB (INDEX TB Guidelines) and Guidelines for the

Introduction of Bedaquiline for drug resistant TB patients in the country. She recently

received the Lupin-TAI Oration award at the National TB Conference 2016, Lucknow, by the

TB Association of India. She is a member of the National Technical Group of RNTCP under

Central TB Division as well as the National Technical Working group for HIV-TB under

NACO, Ministry of Health and Family Welfare, Government of India

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Name:

Lucy Chesire

Institutional affiliation(s): Tuberculosis Consortium

Academic degrees: Bachelor of Science in Community Nutrition

City and country of primary residence: Kenya, Nairobi

Biography Reknown Public Health Specialist working at Tuberculosis Advocacy Consortium, a Kenyan

based national NGO as the Executive Director. I have attended my Bachelor of Science

degree in Community Nutrition from Great Lakes University of Kisumu, and rated Second

Class Upper level and currently undertaking Masters in Public Health at the University of

Liverpool-UK. I have served on a number of reputable International Organization Boards ,

Guideline Development working groups, Technical Workings Groups, this include being the

first patient representative on the Stop TB Partnership Coordinating Board, been an advisor

on UNITAID’s Civil Society Team, Board Member- Communities Delegation-GFATM and

Community Delegation member to the board of the Global Fund to Fight AIDS TB and

Malaria, a former member of the TB REACH proposal steering committee of the Stop TB

Partnership, and a former member of the Strategic Technical Advisory Group on TB of the

World Health Organization in 2007. I currently serve on the Kenya Coordinating Mechanism

to the Global Fund, as a member representation Tuberculosis Communities among others.

7 years experience on guideline development include treatment of drug-susceptible

tuberculosis and patient care & support, use of bedaquiline and update on the WHO policy

guidance on the use of delamanid in children among others as a patient/CSO representative.

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Name: Betina Durovni

Institutional affiliation(s): Health Secretariat Rio de Janeiro City, Federal University of Rio

de Janeiro;

Academic degrees: MD, PhD

City and country of primary residence: Rio de Janeiro City, Brazil

Biography

Betina Durovni is a medical doctor specialized in infectious diseases whose career started in

the centre of the AIDS epidemic in 1986. Dr Durovni has experience in conducting

operational and clinical research on tuberculosis and HIV. As a Principal Investigator or co-

investigator she has participated in many international collaborative studies on tuberculosis

and tuberculosis associated to HIV. She was the Principal Investigator in Brazil in the

THRIO study part of the CREATE consortium and in the GenXpert pilot study funded by the

B&M Gates foundation, and co-investigator in NIH funded collaborative studies with Johns

Hopkins University on innovative approaches for tuberculosis control. She holds a MBA in

health administration and a PhD in medicine from the Rio de Janeiro Federal University and

a MPH from the Johns Hopkins University. Dr Durovni has served as a consultant for

Brazilian MoH and UNAIDS with experience in several countries, she is a member of the

STAG-TB WHO. More recently, Dr Durovni has become involved in the primary care

reform in Rio de Janeiro and is now the undersecretary for surveillance, promotion and

primary care.

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Name: Diana Gibb

Institutional affiliation(s) University College London

Academic degrees

1977 MBChB Distinctions in Medicine, Paediatrics, Pathology (Subtle Gold medal for

medicine) Bristol University

1979 Diploma Obstetrics and Gynaecology Auckland, New Zealand

1982 FRACP Paediatrics (Part 1) Royal Australian College Australia

1985 MRCP Paediatrics Royal College of Physicians, UK

1988 MD Markers of Renal Complications in Diabetic Children Bristol University

1990 MSc Epidemiology London School of Hygiene and Tropical Medicine

City and country of primary residence: Bristol, UK

Biography

Diana is professor of Epidemiology and Programme Leader of the Paediatric Programme of

trials and cohorts at the MRC Clinical trials unit, London. Over the last 20 years she set up

and coordinated a network of clinical trials and cohorts, across Europe, Thailand and South

America mainly addressing questions in paediatric HIV infection. Since 1999 her focus has

expanded to Africa where she runs large trials, addressing strategy questions in adult and

paediatric HIV infection and more recently in malaria and tuberculosis, collaborating widely

with clinical and research centres in 6 countries in East and Southern Africa. Wide inter-

disciplinary collaboration with health economists, pharmacologists, social and basic scientists

and innovators of medicines for children are incorporated into trial programmes. Capacity

development is an important feature of the overseas collaborations, including interactive

courses in paediatric HIV, on-the-ground training in clinical trials and PhD mentorship. She

serves on a number of WHO advisory and guideline committees and continues a clinical

commitment at the HIV Family clinic at the Great Ormond Street Hospital for Children in

London, which she started in 1991.

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Name: Stephen Graham

Institutional affiliation(s): Centre for International Child Health, University of Melbourne,

Australia

Consultant in child TB and lung health, The Union, France

Senior Principal Research Fellow, The Burnet Institute, Australia

Group leader, International Child Health, Murdoch Childrens Research Institute, Melbourne

Academic degrees: MB BS, FRACP, DTCH, PhD

City and country of primary residence: Melbourne, Australia

Biography

Steve Graham is a paediatrician with over 20 years of clinical and research experience in

resource-limited settings in a range of childhood diseases, including tuberculosis (TB),

pneumonia and HIV. He has provided technical assistance on child TB to multiple National

TB Programmes (NTPs) in the Asia-Pacific and African regions. Steve was Chair of the Stop

TB Partnership and WHO’s Childhood TB subgroup from 2011 to 2016, is a member of

WHO’s STAG TB, and Chair of WHO WPRO Taskforce on Child TB. He authored the

international Childhood TB Roadmap (2013), WHO’s Guidance on child TB for NTPs (2006

and 2014), The Union’s Deskguide on child TB management, and in 2010 developed the

recommendations for a new fixed dose combinations for treatment of TB in young children.

Steve’s research interest includes implementation of child TB contact screening and LTBI

management in TB-endemic settings - including Malawi and in Indonesia, where he

supervised original prospective evaluation of WHO’s symptom-based child contact screening.

He is currently collaborating on community-based child TB and contact screening projects in

Viet Nam and Uganda. In 2015, he was awarded the Karel Styblo Public Health Prize for

long-standing contributions to child TB and lung health.

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Name: Diane Havlir

Institutional affiliation(s): University of California, San Francisco

Academic degrees: MD

City and country of primary residence San Francisco, California, USA

Biography Dr. Diane Havlir is Professor of Medicine at the University of California, San Francisco and

Chief of HIV, Infectious Diseases and Global Medicine at San Francisco General Hospital.

She was a physician in training when the AIDS epidemic emerged in the 1980s and has cared

for HIV- infected patients ever since. She has conducted clinical research in TB, HIV and

HIV and TB co-infection for over 25 years, with over 200 publications. She led the HIV/TB

working group of the WHO, plays a leadership role in the WHO HIV Drug Resistance

Surveillance Program and has participated on the WHO Guideline Committee since its

inception. She is currently leading is a community randomized study in East Africa

measuring the health, economic and education effects of testing and treating all HIV infected

persons with a streamlined care approach, with emphasis of assessing his approach on latent

TB infection and incident TB cases.

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Name: Sally Hargreaves

Institutional affiliation(s): International Health Unit, Section of Infectious Diseases and

Immunity, Hammersmith Hospital, Imperial College London, London, UK

Academic degrees: MSc, PhD, FRCPE

City and country of primary residence: London, UK

Biography

SH is a social scientist with an interest in migrant health and infectious diseases. She co-leads

a research team at Imperial College London exploring innovative approaches to migrant

screening in the UK and Europe, and has recently led two studies exploring the feasibility of

doing latent TB screening at key health-care portals where newly arrived migrants present (eg,

the Emergency Room). She has an active interest in the expansion across Europe of more

restrictive approaches to provision of statutory health care to migrants, the barriers to care

this group may face, and implications for uptake of latent and active TB screening in

vulnerable migrant groups. She has authored several papers on the subject of migrant

screening, and previously worked on TB-related issues for MSF in Uzbekistan and

throughout the Former Soviet Union. She is the Research Lead for the European ESGITM

Study Group (ESCMID) into migrant and traveller health, focusing on exploring the

development of screening policies for latent and active TB across Europe.

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Name: Nadia Ismail Abu Sabrah

Institutional affiliation(s): Tuberculosis consultant Physician and Epidemiologist

Former Assistant Director of Chest Disease Directorate and Migrant's

Health/MOH, Jordan

Head of Tuberculosis Division/MOH, Jordan

Deputy National Tuberculosis Program Manager (NTP)/MOH, Jordan

Surveillance Officer of the NTP/ MOH, Jordan

Head of Integrated Management of Childhood illnesses (IMCI)/MOH,

Jordan

Academic degrees:

1982: Medical Doctor (M.D) Degree, M.B.B.CH, Faculty of Medicine, University of

Alexandria-EYGPT

1998- High Specialty Degree in Community Medicine and Epidemiology, Faculty of

Medicine, Jordan University of Science and Technology/Jordan.

City and country of primary residence: Amman, Jordan

Biography

Dr. Nadia Abu Sabrah is a medical doctors and since 1984 as a staff of the National

Tuberculosis Control Program of the Department of Chest Diseases of MOH,Jordan with 30

years experience on treatment of drug-susceptible tuberculosis and patient care & support and

guideline development. She graduated High Specialty Degree in Community Medicine and

Epidemiology, Faculty of Medicine, Jordan University of Science and Technology /Jordan in

1998. Since 1998 surveillance officer of the NTP, and then Deputy of NTP and assistant

Director of chest Diseases Directorate and Migrant's Health in 2000. She has been involved

in the development of general policies, strategic plans for TB control, training and

educational materials, guidelines, standardized operating procedures and manuals for

infection control and management at TB laboratories and TB management units (TBMUs)

and monitor and follow up the implementation of the National TB Control Program's

activities in the country. She also actively participates in the training of doctors and other

health providers in management of Tuberculosis and Practical Approach to Lung Health

(PAL), and lecturer for post graduate doctors for Diploma in Community Medicine. Dr.Nadia

has been involved in framing and preparing National guidelines for Management of TB and

Drug Resistant TB. She has served as one of the led writers of the National Tuberculosis

Control Strategy and the country's proposal applications (Round5&10) which have been

approved by GFATM. Dr.Nadia has published many studies in the international Journals on

Tuberculosis and PAL and approved to be displayed in the Union World Conferences on

Lung Health.

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Name: Alberto Matteelli

Institutional affiliation(s) University of Brescia – WHO Collaborative Centre for TB/HIV

and TB Elimination

Academic degrees: M.D

City and country of primary residence: Brescia, Italy

Biography

He is a specialist in Infectious Diseases and Associate Professor in Infectious Diseases at the

University of Brescia, Brescia, Italy, and Director of the World Health Organization (WHO)

Collaborating Center on Tuberculosis/HIV and TB Elimination, focusing on control of latent

tuberculosis infection (LTBI).

His main fields of interest include TB/HIV co-infection and latent tuberculosis infection.

He served from 2013 to 2015 as a medical officer at the THC Unit, GTB, WHO Geneva,

where he contributed to the development of the 2015 WHO Guidelines on latent tuberculosis

infection. He was involved in the overall agenda for the scale-up of LTBI activities. He

contributed to WHO guidelines development process in other areas, including the

consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV

infection – 2016 recommendations for a public health approach.

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Name: Lindiwe Mvusi

Institutional affiliation(s): National Department of Health, South Africa

Academic degrees: B Sc, CDE, MBCHB

City and country of primary residence: Johannesburg, South Africa

Biography

A medical practitioner with post graduate training in occupational and public health

programmes. Sixteen years experience in clinical work in the private and public sectors,

before joining the National Department of Health as TB programme manager. Current

responsibilities include policy formulation, guideline development, strategic plan

development, planning, coordination of training, surveillance, monitoring and evaluating the

implementation of the national policies, overall coordination of the TB programme which

includes the private sector, business/ industry, correctional services and military health

services. I have served as technical advisor on the WHO DOTS Expansion Working Group,

TB/ HIV and MDR-TB Working Groups. I currently serve in the National Essential

Medicines List Committee

Skills and experience

I have been involved in the national guideline development for Tuberculosis, TB Preventive

therapy, Multi drug resistant TB and Infection Prevention and Control. The specific skills and

experience I will be bringing into this process are;

clinical patient management, programmatic management and therefore provide end

user perspectives.

Evidence review

Formulation of the PICO questions

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Name: Nandi L Siegfried

Institutional affiliation(s) [current and in the prior four years]

Independent (0.8fte)

Chief Specialist Scientist, Medical Research Council of South Africa (0.2fte)

Associate Professor, Faculty of Health Sciences, University of Cape Town

Academic degrees

MBChB, MPH (Hons), FCPHM (SA), DPhil (Oxon)

City and country of primary residence

Cape Town, South Africa

Biography

I am a South African public health physician working as an independent consultant based in

Cape Town. Following several years in clinical medicine, I transferred to a research career

focused on clinical epidemiology and trials methods. I worked for a decade at senior

management level at the South African Medical Research Council, where I was co-director

of the South African Cochrane Centre and Deputy Co-ordinating Editor of the Cochrane

HIV/AIDS Review Group. In 2011 I commenced working as an independent clinical

epidemiology consultant.

As an independent consultant I provide assistance and guidance, as well as technical support

to international, national, institutional and non-government agencies in the healthcare sector.

Most notable is my role as Chair, Technical Advisor and/or Methodologist to 13 World

Health Organization Clinical Guidelines Development Groups and serving as the South

African representative on the Organization for Cooperation and Economic Development

Working Group on Multinational, Non-commercial Clinical Trials.

I have a thorough knowledge of the methods required for high quality clinical trial conduct,

am highly experienced in systematic review methodology and knowledge translation, and my

public health training affords me a broad perspective across the healthcare arena. As a South

African who has worked in neighbouring African countries, I have experience and

knowledge of the healthcare challenges facing low- and middle-income countries. I have

published widely and enjoy teaching and lecturing.

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Name: Liani Smit

Institutional affiliation(s): University of Stellenbosch and Western Cape Department of

Health

City and country of primary residence: Cape Town, South Africa

Academic degrees: MBChB, Dip HIV Management (SA), DCH (SA)

Biography

Liani Smit is a medical doctor and TB advocate with a special interest in genetics and

tuberculosis. After obtaining her medical degree from the University of Stellenbosch, in 2008,

she has worked on the frontline of South Africa’s TB and HIV epidemic. Following a

personal experience with pulmonary TB in 2010, she began advocating for the risks of

occupational TB in healthcare workers as a member of the non-profit organisation, TB Proof.

In 2015 she became a member of the Community Research Advisors Group (CRAG), which

works to ensure the participation and engagement of affected communities in research

conducted by the CDC’s TB Trials Consortium (TBTC). Liani is the CRAG representative on

the LTBI protocol team for the TBTC’s Study 37

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Name: Si Thu Aung

Institutional affiliation(s): Programme Manager, NTP Myanmar)

Academic degrees: M.B.,B.S, D.T.C.D, M.P.H

City and country of primary residence: Nay Pyi Taw, Myanmar

Biography Dr. Si Thu Aung is Programme Manager of National TB Programme, under

Department of Public Health, Ministry of Health, Myanmar. He graduated

Diploma in TB & Chest Diseases from University of Medicine (1) in 2003 and

M.P.H from University of Public Health in 2008. His main responsibilities in TB

control in Myanmar are; programme management, coordination with other

implementing partners and research work. He conducted a lot of operational

research in the areas of epidemiology, health system research, nation-wide TB

prevalence, mortality & drug resistance surveys in order to to enhance

utilization of research findings by community, service providers and policy

makers. Under his stewardship, NTP has successfully developed National

Strategic Plan (2016-2020) for TB control in Myanmar. He has been working for

NTP since 2004 and as a programme manager since 2014.

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Name: Nguyen Van Hung

Institutional affiliation(s): Department of Microbiology and National Tuberculosis

Reference Laboratory - National Lung Hospital, Vietnam.

Academic degrees: PhD, MD

City and country of primary residence: Hanoi City, Vietnam

I received the MD degree in Hanoi Medical University in 1985, the PhD degree and Assoc

Prof title in Science in Medicine,Vietnam, in 1995 and 2016, respectively. I have 27 years

working experience in Clinical Microbiology at National Lung Hospital, of which the most

recent 11 years have been as the Head of Department and also the Leader of Laboratory

Team under the Vietnam NTP. Vietnam NTP successes were recognized by WHO, in that

Lab network has great contribution. Almost WHO recommended techniques for TB have

been applied with high quality in laboratories. Moreover, NRL succeeded in getting

accredited ISO 15189 from 2012.

In May, 2016, I selected as a member in GLI Core Group of WHO. Regarding to LTBI, I had

the presentation in the first meeting of Global Consultation on the Programmatic

Management of LTBI in Seoul, April, 2016. In present, I have contribute to implementing 02

studies in relative to LTBI (The ACT4 and V-Quin Trial).

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Name: Marieke Van der Werf

Institutional affiliation(s): European Centre for Disease Prevention and Control

Academic degrees: MD, PhD, MSc, MPH

City and country of primary residence: Stockholm, Sweden

Biography

Marieke J. van der Werf is the head of the Disease Programme Tuberculosis at the European

Centre for Disease Prevention and Control in Stockholm since 2012 where she is responsible

for the scientific and technical work of the Centre on tuberculosis surveillance, diagnosis,

guidance development, and country support.

She was trained as a medical doctor, in biomedical sciences, and in public health and is a

registered epidemiologist. She obtained her PhD in 2003 and published more than 100

articles in international peer-reviewed journals.

She has worked in Europe, Africa and Asia and provided technical assistance and built

capacity for epidemiological and operational research on topics relevant for tuberculosis

prevention and control. She participated in international policy and guidelines development

groups, such as the World Health Organization STAG-TB and the Task Force Impact

Measurement.

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Name: Wim P. Vandevelde

Institutional affiliation(s): Global TB Community Advisory Board

Academic degrees: Bachelor of Laws studies

City and country of primary residence: Cape Town, South Africa

Biography

For more than a decade Wim Vandevelde has been committed to full time action on HIV,

Hepatitis and TB advocacy and Community involvement in medical research in Europe and

globally. Prior to his health advocacy work, Wim worked in the marketing communications

sector and has extensive experience in the banking industry in Europe. A native of Bruges,

Belgium, Wim speaks fluently Dutch, English, French and Portuguese. He lives in Cape

Town, South Africa, since 2012.

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Name: Irina A. Vasilyeva

Institutional affiliation(s):

Director 07.2016 To present Research Institute of

Phthisiopulmonology of

I.M. Sechenov First Moscow State

Medical University, 4, Dostoyevsky Str,

Moscow

Chief TB

specialist of

the Ministry

of Health

(MoH) of the

Russian

Federation

(RF)

06.2013 To present MoH RF, Moscow

Head of TB

Department

07.2008 06. 2016 Central TB Research Institute of the

Russian Academy of Medical Sciences

(CTRI RAMS), 2, Yauzskaya alley,

Moscow

Academic degrees: Doctor of Medical Sciences

Professor

City and country of primary residence: Moscow, Russian Federation

Biography

After graduation from the I.M.Sechenov First Moscow Medical Institute, I joined the TB

residency program at the Central TB Research Institute of the Russian Academy of Medical

Science (CTRI RAMS).

In 2008, I became the head of the leading scientific and clinical division of CTRI where an

advance center for multidrug-resistant TB (MDR-TB) was established.

Starting 2013, I combined my work at the CTRI with the responsibilities of the chief non-

staff phthisiologist of the Russian Ministry of Health.

In July 2016, I was appointed as a director of the Research Institute of Phthisiopulmonology

of I.M. Sechenov First Moscow State Medical University.

My research expertise includes various aspects of M/XDR-TB treatment, comorbidities

(TB/HIV, TB, and diabetes mellitus), development of TB chemotherapy regimens based on

molecular genetic methods for diagnosis of mycobacteria drug resistance, as well as

development of measures for TB prevention in patients with HIV and diabetes.

At the present time, being a chief TB expert and the NTP leader, I am responsible for

management of TB care in the Russian Federation. Under my leadership, the following

documents were developed: the 2020 TB care development strategy in the Russian Federation,

the National plan for prevention of M/XDR-TB and TB/HIV transmission, modern

approaches to drug supply management and TB treatment management, and updates of the

legal TB documents; the implementation of the state-of-the-art medical and managerial

technologies in TB practice is in progress.

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I am the president of the Russian Society of Phthisiologists, editor-in-chief of the magazine

“TB and Pulmonary Diseases”, a member of the WHO STAG-TB group in 2014-2016.

I have more than 160 scientific publications, including 3 monographs and 6 textbooks for

physicians.