GliorganizzatorividannoilbenvenutoalprimoZebraFishItalianMeeting(ZFIM)

Padova,2-3Febbraio2017Comitatoorganizzatore:

FrancescoArgentonUNIPDMariaCaterinaMioneUNITNMarcoPrestaUNIBSMassimoSantoroUNITOPaoloSordinoSZNA.DohrnStefaniaFantinoTECNIPLAST

ComitatoLocale:

NatasciaTisoUNIPDAndreaVettoriUNIPD

SegreteriaOrganizzativa

CeciliaZattaraDanielaRosinMariaMannoGiuseppeCortese

KINDLYSUPPORTEDby

PROGRAMMAFebruary2nd2017

Registration:8.00-9.15Welcome:9.151stMorningsession9.30-11.00ChairpersonN.Tiso 6x15’presentations(Neurosciencesandbehaviour)

1) TyroneLucon-Xiccato,Padova,Newparadigmsforstudyinglearningandmemoryinzebrafish2) DavidePotrich,Trento,QuantityDiscriminationbyZebrafish(Daniorerio)3) ClaudioAgnisola,Napoli,CantheEarth-strengthmagneticfieldinfluencetheorientationtowaterflowsin

zebrafish?4) FilippoDelBene,Paris,Decipheringanatomyandfunctionofaninter-hemisphericneuralcircuitinthe

zebrafishoptictectum5) Jean-MichelCioni,Cambridge,UK,CytoplasmicFMR1-interactingprotein2regulatesaxonalsortinginthe

optictract6) RosaMariaSepe,Biology,Napoli,Importantroleofendocannabinoidsignallinginthedevelopmentof

functionalvisionandlocomotioninzebrafishCoffeeBreak2ndMorningsession11.30-13.00ChairpersonM.Mione 6x15’presentations(DiseaseModelsI)

1) DianaCorallo,Padova,RoleofLIN-28Binneuralcrestcelldevelopment,differentiationandoncogenesis2) AnnaPistocchi,Milano,Fromzebrafishtohuman:cohesinsdysregulationandleukemia3) AlessandroCellerino,Pisa,Fromthebushtothebench:thegenomeofashort-livedafricanfishreveals

novelaspectsofthegeneticcontrolofvertebrateaging4) MarinaMione,Trento,Apreclinicalzebrafishmodelofbraintumorwithalternativemechanismsof

telomeremaintenance(ALT)5) ValentinaTonelotto,Padova,ZebrafishasamodelfordissectingthesignalsregulatedbyCollagenVI:novel

insightsonCOL6-relatedneuromusculardisorders6) MariaMarchese,Pisa,Zebrafish:atooltostudymusculardystrophies

BuffetLunchandPostersession13.00-14.301stAfternoonsession14.30-15.45ChairpersonM.Presta 5x15’presentations(DiseaseModelsII)

1) StefaniaBellesso,Padova,DeregulatedFGFsignalingsubstantiallycontributestoearlyosteogenicdefectsinMucopolysaccharidosistypeII.

2) ValeriaMastrodonato,Milano,AmodelofCEDNIKsyndromegeneratedbyCRISPR/Cas9geneediting3) MarcoSchiavone,Padova,ProtectiveeffectofAlisporivir-acyclophilininhibitorwithout

immunosuppressiveactivity-inDuchennemusculardystrophy4) GiuseppePaganini,Brescia,b-galactosylceramidaseaffectsmelanocytedifferentiationandneoplastic

progression5) GiuliaFasano,Napoli,EffectsofMethylcyclopentadienylManganeseTrycarbonilondopaminergicneurons

inzebrafishCoffeeBreak2ndAfternoonsession16.15-18.00ChairpersonM.Santoro

7x15’presentations(Cardiovascular,endocrineandmetabolism)1) DavidePradella,Milano,Nova2alternativesplicingregulationoftheNetrinreceptorUnc5bduring

angiogenesis.2) ClaudioLaquatra,Padova,Zebrafish(Daniorerio)asamodeltostudythepathophysiologicalroleofthe

mitochondrialchaperoneTRAP1.3) FedericaMarelli,Milano,Zebrafishasanewmodeltostudyinvivothefunctionalconsequencesofhuman

THRAvariants4) NicolaFacchinello,Padova,Generationandcharacterizationofazebrafishnullmutantforthe

glucocorticoidreceptorgene.5) MonicaBeltrame,Milano,AnovelSox/Notchregulatorynetworktofine-tunezebrafishvascular

development6) GiuseppeMontalbano,Messina,Melatonintreatmentsuppressesappetitegenesandimprovesadipose

tissueplasticityindiet-inducedobese(DIO)zebrafish.7) ImmacolataPorreca,ArianoIrpino,Invivocharacterizationofalongnon-codingRNAduringdevelopment

February3rd20171stMorningsession9.30-10.30

PlenaryLectureProf.Stainier“Cardiomyocytebehaviorandgeneticcompensationinzebrafish”.

CoffeeBreak2ndMorningsession11.00-12.30ChairpersonD.Stainier

6x15’presentations(DevelopmentandOrganogenesis)1) JessicaGuerra,Brescia,Ptx3baffectsprimaryciliumfunctionduringzebrafishdevelopment2) DanielaZizioli,Brescia,Zebrafishsialidaseneu3.2:insightonitsroleduringzebrafishdevelopment3) MargheritaPeron,Padova,Stat3-dependentmitochondrialDNAtranscriptiondrivesstemcellsproliferation

inzebrafish4) GiudittaRurale,Milano,UnravelingtheSonicHedgehog-Glis3pathwayinvolvementinthespecificationof

thethyroidglandinzebrafish5) PamelaFloris,Milano,RoleoftheSMYD3methylaseinembryonicstemcellsdifferentiationandzebrafish

development6) ElenaGuzzolino,Pisa,MiR-182isaTbx5effectorduringheartdevelopmentinzebrafish

BuffetLunchandPostersession12.30-14.301stAfternoonsession14.30-15.45ChairpersonS.Fantino 5x15’presentations(HusbandryandHealthissues)

1) LiviaD’Angelo,Napoli,Legislativeaspectsbehindzebrafishresearch2) TommasoSala,Buguggiate,HowtoproperlyplanaZebrafishfacility:theimportanceofthelayout.

Zebrafishbreeding:astandardoverviewandlatestimprovements.3) LudovicoScenna,Padova,ZebrafishHumaneendpointsandHealthmonitoring4) MassimoFoà,Ludwigsburg,DesigninghealthmonitoringschemeforZebrafish5) VincenzoCavalieri,Palermo,ThezebrafishfacilityoftheMediterraneanCenterforHumanHealthAdvanced

Biotechnologies

CoffeeBreak2ndAfternoonsession16.15-17.15ChairpersonP.Sordino 15’presentations(Technologies)

1) LapoTurrini,Firenze,FunctionalimagingofzebrafishneuronalactivitybyBesselillumination-basedSPIM2) SaraGargiulo,Napoli,Imagingofadultzebrafishmodels3) RosarioLicitra,Pisa,Investigatingfishmealreplacementwithinsectmealin“aquafeed”usingzebrafish

(Daniorerio)asanimalmodelCommunitymeeting17.20-18.00

POSTERS

p1 Caldara Gaetano

Felice

Laws,GuidelineandwelfareinZebrafish

p2 Fronte Baldassare Investigationsontheeffectofß-glucanontissues

regeneration,woundhealinganddiseaseresistance,using

zebrafish(Daniorerio)asanimalmodel

p3 Fronte Baldassare Effectsoffishmealreplacementwithinsectmealonintestinal

morphometryinzebrafish(Daniorerio)

p4 Gabellini Chiara Roleofthechromatinregulatorsetd5duringzebrafishbrain

development

p5 Flavia

Frabetti

Gianluca

Deflorian

CYYR1:anewgeneinvolvedinHh-mediatedmyogenesisand

neuromastsdifferentiationduringzebrafishdevelopment.

p6 D'Aniello Salvatore NovelimplicationsinNeurotrophinsduringthedevelopment

ofthezebrafishnervoussystem

p7 D'Aniello Enrico DepletionofRetinoicAcidReceptorsInitiatesaNovelPositive

FeedbackMechanismthatPromotesTeratogenicIncreasesin

RetinoicAcid

p8 Finazzi Dario Down-regulationofcoasy,thegeneassociatedwithNBIA-VI,

reducesBmpsignaling,perturbsdorso-ventralpatterningand

altersneuronaldevelopmentinzebrafish.

p9 Agnisola Claudio CantheEarth-strengthmagneticfieldinfluencethe

orientationtowaterflowsinzebrafish?

p10 Terzibasi

Tozzini

Eva Disruptionofcircadianrhythmsinducesimpairmentofadult

neurogenesisandgliosisinNothobranchiusfurzeribrain

p11 Guarienti Michela Invivocharacterizationofbehavioralandpharmacological

effectsofmethylxanthinedrugsinzebrafishembryos.

p12 Cellerino Alessandro Nothobranchiusfurzeriasanovelmodelorganismtostudy

thegeneticarchitectureoflifespanevolution

p13 Martorano Laura ModellingmtDNAdepletionsyndromesinDaniorerio

p14 Santangeli Stefania EpigeneticroleofBPAonzebrafish

p15 Bragato Cinzia Atranslationalapproachtoneuromusculardiseasesbasedon

zebrafishstudies:fromhumantozebrafishandback

p16 Carnovali Marta Zebrafishscaleasinnovativeread-outsystemforbone

metabolismstudies:theglucocorticoid-inducedosteoporosis

model

p17 Sicca Federico Applyingmorphantzebrafishlarvaeformodelingepilepsyin

Kirchannelsdisorders

p18 Tregnago Claudia CREBengagesC/EBPδtoinitiateleukemogenesis

p19 Priami Chiara Theroleofthep53/p66Shcpathwayindevelopmentand

aging:ZebrafishandNothobranchiusasmodelorganisms

p20 Muñoz Leonel Metastaticpotentialofhumancoloncancercelllinesin

zebrafishxenograftsareassociatedtotheexpressionof

stemnessandcelladhesionmarkers.

p21 Nittoli Valeria Theneuroinflammatoryresponsefollowingacuteseizures

duringzebrafishbraindevelopment.

p22 Notarstefano Valentina DetrimentaleffectsofdiisononylphthalateonDaniorerio

reproduction

POSTERS

p23 Ori Michela Daniorerioasmodeltounravelnewpathological

mechanismsandtodevelopnewtherapiesagainst

glioblastoma

p24 Khatri Deepak OverexpressionofhumanmutantPANK2mRNAsinzebrafish

embryostogaininsightaboutPKANpathogenesis

p25 LaSpina Martina PterostilbenepartiallyrescuesthephenotypeofCollagenVI

dystrophiczebrafishmorphants

p26 Lidron Elisa MCUknock-downimpairsskeletalmuscleandmotorneuron

developmentinzebrafishembryo

p27 Casarosa Simona AutosomalrecessiveRetinitisPigmentosa:targetingIMPG2

p28 Varrinelli Marco Knock-downandknock-out:useoftwotechniquesto

understandtheroleofAP-1complexinzebrafish

p29 Anelli Viviana Generationandcharacterizationofzebrafishmodelsofuveal

melanoma

p30 Pezzotta Alex Sox18:ofmorphantsandmutants

p31 Meneghetti Giacomo CRISPR-Cas9mediatedknockoutofzebrafishepg5geneto

studyitsfunctionsduringdevelopmentandadultlife

p32 Barca Amilcare InvivomonitoringofpHvariationsinthezebrafishgutlumen

afteroraladministrationofion/acid-basetransportinhibitors

p33 Verri Tiziano Teleostfishmodelsinmembranetransportresearch:the

PEPT1(SLC15A1)H+-oligopeptidetransporterparadigm

PARTECIPANTICognome Nome Citta Abramo Francesca Pisa Agnisola Claudio Napoli Altafaj Albert VERONA Andreazzoli Massimiliano Pisa Anelli Viviana Trento Angiulli Elisa roma Baldassare Fronte Pisa Barca Amilcare LECCE Bassi Ivan MILANO Battioni Francesca VERONA Baudet Marie-Laure Trento Bellesso Stefania Padova Beltrame Monica MILANO Bertolucci Cristiano Ferrara Bibbiani Carlo Pisa Borsani Giuseppe Brescia Bragato Cinzia Milano Brogi Letizia Pisa Caldara Gaetano Felice San Biagio Platani Candiani Simona Genova Carnevali Oliana Ancona Carnovali Marta Legnano Carra Silvia Novate Milanese Casadei Raffaella RIMINI Casarosa Simona Trento Cavalieri Vincenzo Palermo Cellerino Alessandro Pisa Cioni Jean-Michel Cambridge Corallo Diana Padova Corsinovi Debora Pisa Cozzarini Elisa Padova D'Agostino Ylenia Serino D'ANGELO LIVIA BUGUGGIATE D'Angelo Donatella Saronno D'Aniello Enrico Pozzuoli D'ANIELLO SALVATORE NAPOLI Dalla Valle Luisa Padova de girolamo paolo napoli de Latouliere Luisa Bracciano Del Bene Filippo Paris Ducano Nadia Torino Ek Olivier Padova Facchinello Nicola Padova Fasano Giulia Naples FINAZZI DARIO Brescia FLORIS PAMELA QUARTU SANT'ELENA Frabetti Flavia Bologna Frigato Elena Ferrara Fronte Baldassare Pisa Fuochi Sara Calco Gabellini Chiara Pisa Gargiulo Sara Naples Germano Giuseppe Padova Ghigna Claudia Pavia Giuliodori Alice padova Guarienti Michela Pontoglio

Guerra Jessica Brescia Guglielmi Valeria Verona Guzzolino Elena pisa Khatri Deepak Brescia La Spina Martina Padova Laquatra Claudio Padova Licitra Rosario Pisa Lidron Elisa PADOVA Lucon Xiccato Tyrone Padova MANZONI MARTA Brescia Marchese Maria Calambrone Marchetto Giulia Sesto fiorentino MARELLI FEDERICA MILANO Mario Erika Padova Martinelli Diego Portici Martorano Laura Padova Mastrodonato Valeria MILAN Mazzeo Ilaria BRESCIA Meneghetti Giacomo PADOVA Messina Andrea Trento moleri silvia cernusco sul naviglio Montalbano Giuseppe Messina MORA MARINA Milano Muñoz Leonel Karlsruhe naef valentina pisa Neotti Marco Guido Novate Milanese Nittoli Valeria Napoli Notarstefano Valentina Ancona ORI MICHELA Pisa Paganini Giuseppe Orzivecchi Pallafacchina Giorgia Padova Peron Margherita Padova PERSANI LUCA Milano Pestarino Mario Genova Pezzotta Alex Montello Piaggio Giulia Roma Pistocchi Anna Milano Pitto Letizia Pisa Pizzetti Fabrizio Bologna Porreca Immacolata Ariano Irpino Potrich Davide Trento Pradella Davide Gravedona ed Uniti Precazzini Francesca Trento Priami Chiara Milan Rasola Andrea Padova Robbiati Sergio BRESCIA Rottoli Francesco Calco Rurale Giuditta Cologno monzese Sandonà Dorianna Padova Santangeli Stefania Ancona Santorelli Filippo M Calambrone-Pisa Scenna Ludovico Padova Schiavone Marco Padova Sepe Rosa Maria Mirabella Eclano Sicca Federico Pisa soardi michela Padova TARTAGLIA MARCO ROMA Tedeschi Elisa Verona Terzibasi Tozzini Eva Pisa Tiso Natascia Padova

Tobia Chiara Brescia Toni Mattia Roma Tonini Gian Paolo Padova Tonon Federica Trieste Tregnago Claudia Padova Tressoldi Enrico Tommaso brescia Turrini Lapo Sesto Fiorentino Valenti Maria Teresa Verona Valentina Tonelotto Fontaniva Vanzi Francesco Sesto Fiorentino Vattemi Gaetano Verona Verri Tiziano Lecce Vettori Andrea Padova Voltan Silvano Calco Zatti carlo Padova Zennaro Cristina Trieste Zezza Daniela Roseto degli Abruzzi ZIZIOLI DANIELA SAN FELICE DEL BENACO ORGANIZZATORI Mione Marina TRENTO Argenton Francesco PADOVA Fantino Stefania BUGUGGIATE Presta Marco BRESCIA Santoro Massimo TORINO Sordino Paolo NAPOLI TISO NATASCIA PADOVA VETTORI ANDREA PADOVA SPONSORS Cicuttin Marco NIKON Ricci Cristiana NIKON Baronci Alice NIKON MAYO DAVID IDEXX FOA MASSIMO IDEXX Borges Ana Cristina IDEXX Tetteroo Corine NOLDUS Liberati Carlo PLAISANT LIVIA D'Angelo NAPOLI SALA TOMMASO TECNIPLAST Batut Eric VIEWPOINT Balbot Antoine VIEWPOINT Orellana Katherina LEICA Microsystem Morelli Davide LEICA Microsystem CIRELLI ALESSANDRO LEICA Microsystem

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ZFIM

FFSS-ZFIM= 800m

ZFIM-Centro Città=800m

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