Introduction of DNA Variants to Combat

Insulin Resistance

Genesis Linares

Predictors- AOPP oxidative

stress markers- Glucose,

cortisone, leptin levels

- Gender- Age

Obesity-BMI- HOMA-IR scale

Insulin Resistance Research

Role of specific UCP2- UCP3 alleles.

Increased need for large studies to be done on the role that UCPs play in controlling insulin resistance.

Improving UCP2-UCP3 research

http://www.scibx.com/scibx_main/fig_tab/20080828_F1.html

Hypothesis:The UPC2- UPC3 C alleles are

responsible for warding off the development of insulin resistance in the adolescent population.

Ethics:- Informed Consent

(informing parents)- Fasting regimen- Minimal Risk

Procedures:- Obtain an a total of 30

participants:• 10- Obese, non- insulin

resistant• 10- Obese, insulin resistant• 10- Non-obese, insulin

resistant • (BMI (27.02) and Protein

Oxidative Marker, AOPP)- Mean age of 13- Concentrate on the C allele,-Blood Samples every other

week (12 hr fasting) - Anthropometric

measurements

Method

◦ Shows importance of UPC2- UPC3 to insulin resistance

◦ Furthers studies that have been made.◦ Helps support an arising idea◦ Leads to further research and analyses◦ Will aid in bettering medication

Rationale

Resource Price Yearly Fee

Scales $202.18 One time fee

Syringes $34.20 $410.40

Participants $450 $5,400 .00

Total $686.38 $5810.40

Budget

External hard drive

Weekly Print out

Data Management

http://lifewordstoday.com/external-hard-drive/