Gastrointestinal system. The mouth Teeth (caries) Action of Streptococci on dietary sugars Leads to...
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Transcript of Gastrointestinal system. The mouth Teeth (caries) Action of Streptococci on dietary sugars Leads to...
![Page 1: Gastrointestinal system. The mouth Teeth (caries) Action of Streptococci on dietary sugars Leads to pulpitis and abscess.](https://reader030.fdocuments.net/reader030/viewer/2022032701/56649c8b5503460f9494550b/html5/thumbnails/1.jpg)
Gastrointestinal system
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The mouth
Teeth (caries) Action of
Streptococci on dietary sugars
Leads to pulpitis and abscess
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Oral mucosa
Squamous epithelium Subject to infection
Herpes virus Candida Hairy leukoplakia (HIV associated –
caused by EBV)
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Oral cancer
Associated with tobacco (chewing) and alcohol
Clinical preinvasive lesion (leukoplakia)
Squamous carcinoma Poor prognosis unless
detected early
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Sites of oral cancer
Floor of mouth Side of tongue Palate Back of tongue
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“Field cancerisation”
High rate of multifocal tumour 5 year survivor has a 35% chance of
developing a new primary tumour
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Salivary glands
Sialadenitis Viral (mumps) Bacterial, associated with:
Dry mouth Duct obstruction by stones
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Salivary tumours
Benign: Pleomorphic
adenoma Warthin’s tumour
Malignant: Muco-epidermoid
tumour Adenoid cystic
carcinoma Adenocarcinoma
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Tumours
In the bigger glands most tumours are benign
More often malignant in minor salivary glands
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Pleomorphic adenoma
Most common salivary tumour
Mucoid “cartilagenous” stroma with epithelial proliferation
Prone to local recurrence
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Warthin’s tumour
Columnar epithelium with lymphoid stroma
Benign
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Adenoid cystic carcinoma
Epithelial cell islands with microcystic change
Very locally infiltrative (especially around nerves) but metastasises late