Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am...
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Transcript of Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am...
![Page 1: Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am soon to be leaving to go to The University of Liverpool.](https://reader036.fdocuments.net/reader036/viewer/2022062519/5697c01b1a28abf838ccfb1f/html5/thumbnails/1.jpg)
Funding for Tsetse Genome Sequencing in the USA
Neil Hall
TIGR (soon to be renamed JCVI) But I am soon to be leaving to go to The University of Liverpool anyway
![Page 2: Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am soon to be leaving to go to The University of Liverpool.](https://reader036.fdocuments.net/reader036/viewer/2022062519/5697c01b1a28abf838ccfb1f/html5/thumbnails/2.jpg)
Genomics funding in the US
• All (99.9%) of medical sequencing is funded by two NIH contracts.– Microbial Sequencing Contact – TIGR, Broad.– National Human Genome Research Institute,
TIGR/JCVI, Broad, WashU, Agencourt, Baylor• MSC – Pathogens, parasites, Vectors
– But has turned down a white paper on Glossina • NHGRI – Models and genomes of evolutionary
importance. • Pathogen and vector databases funded through
the NIAID-BRCs
![Page 3: Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am soon to be leaving to go to The University of Liverpool.](https://reader036.fdocuments.net/reader036/viewer/2022062519/5697c01b1a28abf838ccfb1f/html5/thumbnails/3.jpg)
![Page 4: Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am soon to be leaving to go to The University of Liverpool.](https://reader036.fdocuments.net/reader036/viewer/2022062519/5697c01b1a28abf838ccfb1f/html5/thumbnails/4.jpg)
Informatics funded through MSC and BRCs
![Page 5: Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am soon to be leaving to go to The University of Liverpool.](https://reader036.fdocuments.net/reader036/viewer/2022062519/5697c01b1a28abf838ccfb1f/html5/thumbnails/5.jpg)
![Page 6: Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am soon to be leaving to go to The University of Liverpool.](https://reader036.fdocuments.net/reader036/viewer/2022062519/5697c01b1a28abf838ccfb1f/html5/thumbnails/6.jpg)
![Page 7: Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am soon to be leaving to go to The University of Liverpool.](https://reader036.fdocuments.net/reader036/viewer/2022062519/5697c01b1a28abf838ccfb1f/html5/thumbnails/7.jpg)
Changes to NHGRI Mission
• Three centers not five
• Must promote “new sequencing technology”
• Previous award involved understanding the human genome.
• Now it must address “human health”
• Will now actively seek to sequence pathogens, parasites and vectors
![Page 8: Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am soon to be leaving to go to The University of Liverpool.](https://reader036.fdocuments.net/reader036/viewer/2022062519/5697c01b1a28abf838ccfb1f/html5/thumbnails/8.jpg)
Getting your genome sequenced
• White papers must give a rational and a strategy
![Page 9: Funding for Tsetse Genome Sequencing in the USA Neil Hall TIGR (soon to be renamed JCVI) But I am soon to be leaving to go to The University of Liverpool.](https://reader036.fdocuments.net/reader036/viewer/2022062519/5697c01b1a28abf838ccfb1f/html5/thumbnails/9.jpg)
Caveats
• NHGRI will give your genome to someone you don’t know.
• Sequence will be generated but no informatics is funded.
• The timescale is dictated by NHGRI• Must coordinate with the Sanger.• Must make a rational argument for a finished
sequence. – Why is 3x not enough!