Presented byAmir SadaulaBVSc & AH,8th sem Rampur CampusRoll No: 01

Acute or chronic contagious disease affecting domestic as well as wide range of wild birds

In acute form Septicemia condition with high mortality

The chronic form is also known as “WATTLE Cholera”

World-wide in distribution

Pasteurella multocida gram –ve, non motile, non spore forming

rod shaped bacteria. organism appears bipolar in shape while

stained with methylene blue or Giemsa stain

organism grows well on meat infusion broth enriched with peptone and avium serum

Gas –ve, Oxidase and Catalase test +ve organism killed with common disinfectant

and sunlight

Direct contact between susceptible birds and clinically affected or recovered carriers.

Rodents, and wild birds are sources of indirect infection. Contaminated

Feed bags, equipment, and the clothing of personnel may introduce infection into farm

Intraflock transmission is enhanced by handling birds for vaccination and weighing and by open

watering systems such as troughs and bell drinkers.

Per Acute: Death of large number of birds Acute : two type of manifestations

Pulmonary form : respiratory of distress appearing as sneezing, coughing and gasping, cyanosis prior to death

Septicemic form : fever, depression, anorexia, discharge from mouth and ruffled feathers along with diarrhea. Feces is watery in nature having whitish appearance initially followed by greenish coloration containing mucus

Chronic form: hyperemia and edema of comb and wattles Joint may be swollen. Swellings pit on

pressure. Affection of the joint may lead to lameness.

Mucoid discharge is noted in beak and nostrils.

Exudation may appear from eye (Conjunctivitis) or pharynx (pharyngitis).

Infection spread in the bone of head and or brain leading to in coordination, walking in circle and torticolis

Liver: Enlarged, focal area of coagulative necrosis, massive white or greyish necrotic foci resemble pin head

Heart: pin point hemorrhage in fat Intestine: viscid mucus, petechial

hemorrhage in duodenum Lungs: Pneumonic change Ovary: follicle appear flaccid, congestion,

egg peritonitis Joints: Swollen containing exudate Comb and wattle: swollen unilateral or

bilateral

History and clinical finding Post Mortem finding Demonstration of Organism

impression smear of Liver or Blood staining with Methylene blue Gram –ve Bipolar organism

Serology: Whole Blood aggulutination, AGDT

Newcastle Disease Fowl plague/ Avian Influenza Vitamin A deficiency Fowl Coryza Salmonellosis Mycotoxicity CRD

Gentamicin @ 1gm/2 ltr DW for 5 days Enrofloxacin @ 1ml/2 ltr DW for 5 days Doxycyclin @ 1gm/ltr DW for 5 days Neomycin + Doxycyclin @ 1gm/4 ltr DW for 5

days Sulphonamide @ 2.5- 5 gm/100 birds for 5 days Cholamphenicol @ 1 gm/5 ltr DW for 5 days Supportive therapy:

Livertonic: 5 – 15 ml/100 birds for 7days Immunomodulator: 5-10 ml/100 birds for 7 days Vitamins: 5 – 15 ml/100 birds for 7 days

Maintain good hygiene and sanitation Try to remove recovered which are carrier Biosecurity measure All in all out Vaccination:

Live vaccine: strain of live P multocida found non pathogenic CU strain

Killed bacterins: preparation of one or more serotype chemically inactivated and kept in oil emulsion.

Commerical vaccine: FC inactivated vaccine1st Vaccine @ 8 weeks or Older

S/CRepeat 6 week later S/C