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University of Science & Technology

Faculty of Pharmacy

جامعة العلوم والتكنولوجیا كلیة الصیدلة

Fourth Year : First Semester Courses Titles Code /

No Credit Hours Credit

Hours Pre-Requisites Lecture Practical Tutorial

1 Pharmacology III BPH26 2 1 - 3 BPH25

2 Pharmaceutical Technology III BPH29 2 1 - 3 BPH28

3 Pharmaceutical Chemistry III BPH32 2 1 - 3 BPH31

4 Therapeutics I BPH42 2 - - 2 BPH25, BPH39

5 Integrated Case- Based Learning I BPH46 - - 1 1 BPH42/Co-Req

6 Biopharmaceutics BPH50 2 - - 2 BPH16 7 Pathophysiology II BPH40 2 - - 2 BPH39

8 Structured Practical Experiential Program I BPH51 - 2 - 2 BPH25

9 Professional Skills V BPH21 1 - - 1 BPH20 Total of Credit Hours 13 5 1 19

Fourth Year : Second Semester Courses Titles Code /

No Credit Hours Credit

Hours Pre-Requisites Lecture Practical Tutorial

1 Therapeutics II BPH43 2 - - 2 BPH42

2 Integrated Case- Based Learning II BPH47 - - 1 1 BPH43/Co-Req

3 Drug delivery Systems BPH55 2 - - 2 BPH29 4 Research Methodology UST10 2 - - 2 BPH56/Co-Req 5 Biostatistics BPH56 2 - - 2 UST10/Co-Req 6 Pharmacokinetics BPH57 2 - 2 BPH50 7 Toxicology BPH58 2 - - 2 BPH26 8 Pharmacoepidemology

and Pharmacoeconomics

BPH59 ١ - - ١ BPH26

9 Public Health BPH60 ١ - - ١ - 10 Structured Practical

Experiential Program II BPH52 - 2 - 2 BPH29

11 Professional Skills VI BPH22 1 - - 1 BPH21 Total of Credit Hours 15 2 1 18


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Pharmacology III Programme(s)on which the course is given: Pharmacy Major or minor element of programmes Department offering the programme: Faculty of Pharmacy Department offering the course: Pharmaceutical Sciences Academic year/Level: Fourth year Date of specification approval: / / A-BASIC INFORMATION Title: Pharmacology III Code: BPH26 Credit hours:2+1 Lecture: 28 hrs Tutorial: within practical classes Practical: 13 hrs Total: 41 B-PROFESSIONAL INFORMATION 1-Course Description: This course is dealing with pharmacology of therapeutic agents used in blood disorders and endocrine systems. The course also covers medications used in infectious diseases. Overall aim of course: The scope of this course is to provide students with information about the actions and uses of a number of pharmacologically active drug classes and to explain efficiently the mechanisms by which different members of each class act on their target receptors. They must also be able to discuss professionally pharmacokinetics and pharmacodynamic of drugs acting on blood, endocrine and different infectious diseases. 2-Intended Learning Outcomes of course (ILOs) A-Knowledge and Understanding: The student should be able to:

a.1. Understand the principles of blood homeostasis and drugs acting on blood

disorders.

a.2. Distinguish between different groups of drugs acting on endocrine system

a.3. Recognize the effect of hormones and drugs on endocrinal disorders a.4. Distinguish between different groups of antimicrobial agents

B-Intellectual skills: The student should be able to:

b.1 Retrieve the information about different blood disorders and drugs used. b.2 Evaluate patient’s condition seeking help at the endocrine abnormalities b.3 Sort the proper drugs that are acting on different diseases of endocrine system.


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b.4 Differentiate between agents that are acting on different infectious diseases. C-Professional and practical skills: The student should be able to:

c.1. Choose the suitable medication for blood disorders according to their pharmacokinetics and

pharmcodynamics c.2. Interpret the cause for choosing the suitable medication for different endocrinal, blood and

infectious disorders c.3. Evaluate the gained information during patient counseling to select & provide suitable drugs

for different infectious diseases. D-General and transferable skills: The student should be able to: d.1 Demonstrate critical thinking, decision making, synthesis and interpretation of

pharmaceutical information, and responsibility. d.2 Obtain required scientific information from available sources. d.3 Develop the ability to work with equations and learn how to choose the suitable

medications for different ailments. 3-Contents:

No. Topic Lectures Practical 1 Blood

-Agents used in anemia -Antiprotozoal drugs -Drugs used in disorders of coagulations -Agents used in hyperlipidemia -Anticancer agents

3 3 3 3

2 2


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2

-Endocrine system: -Hypothalamic & pituitary hormones -Thyroid & antithyroid drugs -Parathyroid & regulation of calcium metabolism -Pancreatic hormones & antidiabetic drugs -Adrenocorticosteroids & adrenocortical antagonists - The gonadal hormones & inhibitors -Contraceptive agents Chemotherapeutic drugs: -Introduction -Antibacterial agents -Antifungal & antiviral

3 3 3 3 3 3 3 3 3

2 2 2 2 1

Total 39 13 4-Teaching and learning methods Lectures Computer, data show, white board, marker, OHP. Practical Experimental animals, drugs, laboratory chemicals, anesthetics. 5-Student assessment method To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. Weighing of assessments:

Assessment Weight Description

a First test 15%

b Second test 15%

c Activities 5%

d Final test 35%

e Practical part 30%

Total 100% 6-List of references


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6.1-Course notes (lecture notes and practical notes) prepared by staff members of pharmacology Dept. responsible for teaching students. 6.2-Textbooks: Textbook: Rang, Dale and Ritter Pharmacology (2009) Supplement: Katzung –Basic and Clinical Pharmacology (2009) 6.3-Websites in international network (internet). 7-Facilities required for teaching and learning Laboratory glassware, chemicals, computers, data show and OHP. Course coordinator: Head of department Dr. Doa'a Anwar Ibrahim


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Pharmaceutical Technology III

Programme(s)on which the course is given: Bachelor of Pharmacy Major or minor element of programmes Department offering the programme: NA Department offering the course: Pharmaceutical Sciences Academic year/Level: Third year-Second semester Date of specification approval: / / A-BASIC INFORMATION Title: Pharmaceutical Technology III Code: BPH29 Credit hours: 3 (2+1) Lecture: 28 hrs Tutorial: within classes Practical: 12 Total: 40 B-PROFESSIONAL INFORMATION 1-Course Description: This course describes the basic concepts of prefromulation and unit operations. It relates the basic scientific background to pharmaceutical practice regarding the dosage forms preparation. The basic elements of good manufacturing practice (GMP) will be discussed as well. Overall aim of course: The aim of this course is to describe the scientific and technological aspects preformulation and basic unit operations faced in pharmaceutical industry. The pharmacy students are also expected to recognize and appreciate the importance of good manufacturing practice (GMP). 2-Intended Learning Outcomes of course (ILOs) A-Knowledge and Understanding: The student should be able to:

1. Define the concepts of preformulation and GMP. 2. Discuss the various aspects of unit operations in the processing of active

pharmaceutical ingredients and excipients.


1. Compare between different stages of preformulation. 2. Choose rationally the adjuvants, preparation methods, and equipments of different

formulations.


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C-Professional and practical skills: The student should be able to:

1. Handle chemicals properly and safely. 2. Operate machinery used properly. 3. Collect data from different equipments used. 4. Conduct experiments and analyze results.

D-General and transferable skills: The student should be able to: d.4 Demonstrate critical thinking, synthesis and interpretation of pharmaceutical

information, and responsibility. d.5 Manage time effectively. d.6 Work effectively as a part of team in order to fulfill certain project. 3-Contents:

Week Topic

1-2 Preformulation

3-11

Unit Operations: • Particle size analysis • Particle size reduction • Particle size separation • Powder flow • Mixing • Drying and dryers • Filtration and Centrifugation

12-14 Good Manufacturing Practice

Practical Part: Week Experiment 1 Solubility and dissolution 2 Drug stability I 3 Drug stability II 4 Particle size analysis


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5 Milling 6 Granulation 7 Powder flow I 8 Powder flow II 9 Mixing 10 Mixing Parameters 11 Drying and water content 12 centrifugation 4-Teaching and learning methods

• Lectures (Tools: board, overhead projector, pc and data- show projector). • Practical sessions. • Assignments (Report writing).

5-Student assessment method To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. Weighing of assessments:


a First test 15%

b Second test 15%

c Activities 5%

d Final test 35%


Total 100% 6-List of references 6.1-Course notes provided to the students 6.2-Textbooks:

• Text Book: Pharmaceutical dosage forms and drug delivery systems ( Howard Ansel, Loyd Allen, Nicholas Popovich)


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• Supplement (s) 1- Pharmaceutics: the science of dosage form design (M.E. Aulton) 2- The Theory and Practice of Industrial Pharmacy (Lanchman, L., Lieberman, H.,

and Kanig, J.) 3- Remington: The Science and Practice of Pharmacy

6.3- Websites in international network (internet). 7-Facilities required for teaching and learning Lecture rooms, computers, data show, library, and internet access. Course coordinator: Head of department: Dr. Khaled Al-Tahami


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Pharmaceutical Chemistry III

Program (s) in which the course is given: Bachelor of Pharmacy Major or minor element of programmes Department offering the programme: Pharmacy Department offering the course: Pharmacy Academic year/Level: Fourth year- First Semester Date of specification approval: A-BASIC INFORMATION Title: Pharmaceutical chemistry III Code: BPH32 Credit hours: 2+1 Lecture: 28 hours Tutorial: within lecture classes Practical: 12 Total: 41

B- Professional Information

1- Course Description:

The scope of this course is to build on the knowledge acquired in Pharmaceutical Chemistry I and

II. This course describes the physico chemical properties of drugs and drug action, including

receptor site theories, the synthesis and structure-activity relationships of several classes of

therapeutic agents.

Overall aim of course:

Get deep insight on the chemistry of drugs.

2- Intended learning outcomes of course (ILOs)

A- Knowledge and understanding:

At the end of the course the student should be able to:

a.1. Understand the basic background of the pharmacology and the chemical structures of

drugs.

a.2. Understand the general metabolic pathways of drugs.

a.3. Understand the chemical synthesis of selected drugs.

a.4. Understand the structure-activity relationship (SAR) of drugs.

B- Intellectual skills:


b.1 Discuss and analyze the basic structures of therapeutic groups

b.2 Discuss and analyze the main metabolic pathways of drugs.

C- Professional and practical skills:



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c.1 Guess the pharmacological activity of drugs, based on the structure-activity relationship

(SAR).

c.2 Working in factories, pharmaceutical companies, and other health facilities, in the field of

new drugs design, and quantitative and qualitative determination of drugs.

D- General and transferable skills:

At the end of the course the student should be aware about:

d.1 The importance of continuous self-study of drugs

d.2 Coordinate the basic and the practical knowledge of drugs

3- Contents

Lectures

No. Title Hours 1 NSAID 2 2 General anesthetics, benzodiazepines, barbiturates 2 3 Phenothiazines, butyrophenones, others 2 4 Antiepileptic drugs, doxapram, amphetamines 2 5 xanthines, doxapram, hallucinogens 2 6 TCA, SSRI 2 7 MAOI, others 2 8 Vitamins1 2 9 Vitamins2 2 10 Steroids1 2 11 Steroids2 2 12 Opioid analgesics1 2 13 Opioid analgesics2 2 14 Combinatorial chemistry 2

Total 28 Practical

No. Subject Hours 1 Identification of mefenamic acid 1 2 Synthesis of diazepam 1 3 Identification of diazepam 1 4 Identification of phenobarbitone 1 5 Identification of chlorpromazine 1 6 Identification of imipramine 1 7 Identification of fluoxetine 1 8 Identification of vitamin C 1 9 Identification of vitamin D 1 10 Identification of hydrocortisone 1 11 Identification of hydrocortisone 1 12 Identification of codeine 1 Final Exam 1

Total 12


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4-Teaching and learning methods

Lectures

Computer, data show, white board, marker.

Practical

Laboratory of chemistry.

5- Student assessment method

To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. Weighing of assessments:


a First test 15%

b Second test 15%

c Activities 5%

d Final test 35%


Total 100% 6- References

Textbook:

• John H Block and John M Beale Jr., Wilson and Gisvold’s Textbook of Organic,

Medicinal and Pharmaceutical Chemistry, 2004, 11th Edition, Lippincott Williams &

Wilkins.

Supplement:

• Adel Nofal, Pharmaceutical Chemistry, Damascus University Publications, 2007, 3rd

Edition. (Arabic book)

7- Facilities required for teaching and learning

White board, data show, textbooks and laboratory.

Course coordinator:

Therapeutics I

A-BASIC INFORMATION


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Title: Therapeutics I Code: BPH42

Credit hours: 2 Lecture: 28 hrs

Tutorial: within practical classes

Academic year/ Level: Fourth year, First Semester Total: 28

B-PROFESSIONAL INFORMATION

1-Course Description:

The course deals with selected major disease states and their therapy, especially in the individualization of drug usages. The role of the pharmacist in the provision of optimal patient care through monitoring of patients drug therapy is emphasized.

Overall Aims of Course:

A- Giving knowledge about the patho-physiology of disease.

B- Explain the symptoms and complications of the diseases.

C- Analysis treatment aims and algorithms, drug interactions, dose calculations, side effects of drugs.

D- Recognize the safety of drugs in special groups like children, elderly and pregnancy.

E- Describe the appropriate lifestyle modifications, patient awareness and counseling.

F- Solve the given case according to the correct therapeutic way.

2-Intended Learning Outcomes of course (ILOs)

A- Knowledge and Understanding:

A1- To acquire understand the principals of, patho-physiology, symptoms and complications that relevant to diseases.

A2- To recognize the lifestyle modifications, underlying causes and contributing factors in the development of disease.

A3- To acquire knowledge about drugs and their uses therapeutically concerning their identities, safety, optimum use in medication and contraindications.

A4- Knowledge about populations requiring special consideration when designing a treatment plan.


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A5- Construct an appropriate monitoring plan to assess disease treatment.

A6- To get knowledge about recent researches, articles and advanced studies on drugs treating many diseases


B1- The student can diagnose disease according to their manifestations, investigations and physical examinations

B2- Interpret the clinical features and the diseases related to them.

B3- Solve the case studies according to the therapeutic way.

B4- Interpret patient and clinical data, including patient records held within practice settings.


C1- To acquire skills to diagnosed the case studies precisely.

C2- Evaluate critically observations and measurements, in terms of their significance and theory underlying them.

C3- Give advises for the patients and others on the safe and effective use of medicines.


D1- Interact effectively with patients, the public and health care professionals; includes communication both written and oral.

D2- Solve the problem base relating to given information like patient history.

D3- Writing a report for criticizing of suitable drugs for each case.

D4- Behave with an ethical attitude and approach.

3- CONTENTS:

No. of Hours/week Credit Hours Lecture Title


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Note: 3 clerkship hours equal one credit hour

4-TEACHING AND LEARNING METHODS

4.1 Lectures

Computer, data show, white board, marker, OHP.

4.2 Prac cal

Visiting hospitals to deal with patients and their files

Clerkship Lecture 3 3 4 Gastrointestinal tract

Peptic ulcer + Cases

3 3 4 GERD + Cases 3 3 4 Hypertension (HTN)

3 3 4 HTN…continued + HTN Cases

3 3 4 Coronary Heart Disease(CHD) 3 3 4 Continued CHD + case study

3 3 4 Congestive heart failure (CHF)

3 3 4 Continued CHF + Arrhythmias + Case study

3 3 4 Thyroid disorders Hypothyroidism

3 3 4 Hyperthyroidism + case study

3 3 4 Parathyroid disorders Hypo- + Hyperparathyroidism + Cases

3 3 4 Pancreas disorders Diabetes mellitus (DM)

3 3 4 DM continued + Cases

3 3 4 Rheumatic diseases + Cases

42 56 Total


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5- STUDENT ASSESSMENT METHOD



a First test 20%

b Second test 20%

c Assignments 10% d Final test 50% Total 100%

6- LIST OF REFERENCES

6.1 Course notes (lecture notes and practical notes) prepared by teacher of the subject.

6.2 Textbooks:

Textbook:

Walker and Edwards (eds). Clinical Pharmacy and Therapeutics. 3rd edition (2003).

Supplements: • MARIE A. CHISHOLM-BURNS and others; Pharmacotherapy: Principles &

practice. 2008 • Terry L. Schwinghammer & Julia M. Koehler. Pharmacotherapy Casebook: A

Patient-Focused Approach 7th edition 2009

Integrated Case- Based Learning I Specification

A-BASIC INFORMATION


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Title: Integrated Case- Based Learning I Code: BPH46

Credit Hours: 1hour Lecture: --

Tutorial: 2 hours Clerkship: -

Academic year/ Level: Fourth year, First Semester Total: 28



The course provides opportunities for the practice of medical cases and scenarios to emphasize the concept of clinical pharmacy with the focus on the systems covered in Therapeutic I simultaneously.


G- Explain the symptoms and complications of the diseases.

H- Analysis treatment aims and algorithms, drug interactions, dose calculations, side effects of drugs.

I- Recognize the safety of drugs in special groups like children, elderly and pregnancy.

J- Describe the appropriate lifestyle modifications, patient awareness and counseling.

K- Solve the given case according to the correct therapeutic way.








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3- CONTENTS: Tutorial Credit Hours Tutorial Title

2 1 Gastrointestinal tract Peptic ulcer Cases

2 1 Gastro-esophageal reflux disease Cases

2 1 Cardiovascular tract

Hypertension (HTN) Cases

2 1 Continued HTN Cases


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Note: 2 Tutorial hours equal one credit hour


Tutorial & Group-based discussion


C. Assignments، in class group work, presentations and examinations.

5.1 Assessment schedule:

Assessment Time

First test Week 6

2 1 Coronary Heart Disease(CHD) Cases 2 1 Continued CHD Cases study

2 1 Congestive heart failure (CHF) Cases

2 1 Arrhythmias Cases study

2 1 Thyroid disorders

Hypothyroidism Cases study

2 1 Hyperthyroidism Cases study

2 1 Parathyroid disorders

Hypo- & Hyperparathyroidism Cases study

2 1 Pancreas disorders

Diabetes mellitus (DM) Cases study 2 1 DM continued Cases study

2 1 Rheumatic diseases Cases study

28 14 Total


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Second test Week 12

Final written exam. Week 14

5.2 Weighing of assessments:


a First test 20%

b Second test 20%

c Activities 10%

d Final test 50%

Total 100%



6.2 Textbooks:

Textbook:




Patient-Focused Approach 7th edition 2009 Biopharmaceutics

A- Basic Information


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Title: Biopharmaceutics Code: BPH50 Credit hours: 2 hours Lecture: 28 hrs Tutorial: within classes Practical: - Academic year/ Level: Fourth year, First Semester Total: 28 B-Professional Information 1- Course Description:

The course describes the principles and applications of biopharmaceutics including physico-chemical, physiological and formulation factors affecting drug bioavailability. OVERALL AIMS OF COURSE: A- Define biopharmaceutics, bioequivalence, bioavailability and the parameters involved B- Describe the mechanisms and factors involved in drug absorption C- Explain how drugs are distributed, metabolised excreted and factors affecting them D- Review the role of formulation design in modifying the drug absorption, distribution and elimination E- Explain how drug absorption can be optimized F- Support the characteristics of various drug delivery systems and their impact on the drug pharmacokinetics G- Understand the influence of different physicochemical, physiological and dosage form design on the drug bioavailability E- Design bioavailability and bioequivalent studies

2- Intended Learning Outcomes Of Course (Ilos) A- Knowledge and Understanding: A1- To be able to recognize the different factors affecting GIT absorption A2- To learn how the choice of a certain dosage form can affect drug fate and release in the body A3- To recognize the effect of route of administration on drug availability A4- To know the various aspects of bioavailability and bioequivalence studies B- Intellectual skills: B1- To be able predict effect of various factors on drug release B2- To be able to suggest suitable bioavailability and bioequivalence studies. C- Professional and practical skills: To acquire skills to carry out bioavailability and bioequivalence studies D- General and transferable skills: To have the ability to deal with problems and to come up with solutions during dosage form development and manufacturing.


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3- Contents:

No. of Hours/week

Credit Hours

Lecture Title

Tutorial Lecture

2 2 Introduction, terminology, and basics of biopharmaceutics

2 2 Mechanisms of GIT drug absorption

2 2 Physiological factors affecting drug absorption:

- GIT anatomy - GI components

2 2

Physiological factors affecting drug absorption: - Consistency - pH - gastric emptying

2 2

Physico-chemical factors affecting absorption: - chemical form - partition coefficient - pKa - Crystal form

2 2

Physico-chemical factors affecting absorption: - Particle size - Solvation - Complexation - Adsorption - Stability

2 2 Pathological conditions affecting absorption:

- malabsorption - partial or total gastroenteritis

2 2 Pathological conditions affecting absorption:

- thyroid disorders - liver and renal diseases

4 4 Influence of various dosage forms and their excipients on the bioavailability of drugs

4 4 Influence of various routes of administration on the bioavailability of drugs

2 2

Bioavailability: - definitions - methods of determination of bioavailability using

blood and urine - protocol design of bioavailability assessment - methods of bioequivalence determination

2 2

Bioequivalence: - definitions - methods of determination of bioavailability using

blood and urine - protocol design of bioavailability assessment - methods of bioequivalence determination


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4- TEACHING AND LEARNING METHODS 4.1 Lectures Computer, data show, white board, marker. 4.2 Practical NA 5- STUDENT ASSESSMENT METHOD To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. Weighing of assessments:


a First test 20%

b Second test 20%


6- LIST OF REFERENCES 6.1- Course notes provided to the students 6.2- References: Textbook: Applied biopharmaceutics & pharmacokinetics by Leon Shargel, Susanna Wu-Pong, Andrew B. C. Yu Supplement: Biopharmaceutics and Clinical Pharmacokinetics [Book] by Milo Gibaldi 6.3- Websites in international network (internet). 7- FACILITIES REQUIRED FOR TEACHING AND LEARNING Lecture rooms, computers, data show, library, and internet access.

- 28 28 Total Hours


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Pathophysiology II

Programme(s)on which the course is given: Pharmacy Major or minor element of programmes Department offering the programme: Faculty of Pharmacy Department offering the course: Academic year/Level: Fourth year Date of specification approval: / / A-BASIC INFORMATION Title: Pathophysiology II Code: BPH40 Credit hours: 2hrs Lecture: 28 hrs Total: 28 B-PROFESSIONAL INFORMATION 1-Course Description: This course serves to prepare students for consequent therapeutics courses through introducing the pharmacy students to mechanisms of diseases in several human body systems. Overall aim of course: This course provides pharmacy students with the knowledge of the pathogenesis of various symptoms & diseases affecting the CNS, RT, UT and haematologic system. Altered, physiological functions of human organs are explained and, then described on molecular, cellular, organ & systemic level. 2-Intended Learning Outcomes of course (ILOs) A-Knowledge and Understanding: The student should be able to: a.1. Discuss the etiology, pathogenesis, morphology, local & systemic effects of cell injury due to diseases affecting some major organs like central nervous system system

a.2. Explain the underlying causes of acute and chronic renal failure and disorders of respiratory system. a.3. Discuss the etiology and manifestations of different infectious diseases and blood disorders. B-Intellectual skills: The student should be able to:


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b.1.Differentiate between the different ailments based on their pathophysiology backgrounds b.2. Recognize the importance of paathophysiology in identification of different diseases.

b.3. Assume individual responsibility and accountability in the role of provider of care and manager of care in the application of pathophysiological mechanisms of disease to client care. C-Professional and practical skills: The student should be able to:

c.1. Apply principles of immunology, cancer & basic physiological processes to systemic disease states.

c.2. Evaluate pharmacy research using physiological measurements as a basis for evidenced-based practice

c.3. Participate in discussions about the causes and dynamics of diseases with the knowledge of recent scientific information

D-General and transferable skills: The student should be able to: d.1.Solve problems and work effectively and independently; b.2.Utilise library and computer resources effectively to access and search for information in specified areas, from a range of sources; b.3. Demonstrate competency skills in the role of self-reflection and goal-setting in personal performance and development. B.4. Critically examines the importance of the resources needed to effectively received data 3-Contents:

No. Topic Lectures 1 i-Alterations in Hemostasis and Blood Coagulation

ii- Neoplastic Disorders of Hematopoietic and Lymphoid Origin

2

2 Alterations in the Respiratory System i- Infectious Disorders and Neoplasia

ii- Obstructive Airway Disorders

2

3 Alterations in the Urinary System a) Renal Failure Ú Acute Renal Failure Ú Chronic Renal Failure

2


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4 Alterations in the Nervous System

i- Seizure Disorders ii- The Organization and Control of Motor Function iii- Dementias

4

5 Infectious diseases

4

Total 14

4-Teaching and learning methods Lectures Computer, data show, white board, marker, OHP. 5-Student assessment method To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. Weighing of assessments:


a First test 20%

b Second test 20%


6-List of references 6.1-Textbooks: Textbook: Mattson, K. (February 1, 2006). Essential of Pathophysiology. Concepts of Altered Health States. 2nd edition. Lippincott Williams & Wilkins; ISBN-10: 0781770874 Supplements:

• Porth C. “1998” Pathophysiology. Concepts of Altered Health States. 5th edition. Lippincott- Raven Publishers. New York

• Huether S. “2004” Understanding Pathophysiology. 3rd edition. Mosby. USA. 6.3-Websites in international network (internet). Course coordinator: Head of department:


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Structured Practical Experiential Program I

PROGRAMME(S) ON WHICH THE COURSE IS GIVEN

Major or Minor element of programmes

Department offering the programme: - pharmacy

Department offering the course: - Pharmaceutical Sciences

Academic year / Level 4th year/ 1st semester

Date of specification approval


Title: Structured Practical Experiential Program I Code: BPH51 Credit Hours: 2 credit hours and 120 experien al hours

COURSE DESCRIPTION

The primary intent of the Community IPPE is to facilitate students’ continuing professional development in the context of the community pharmacy practice setting. Through structured activities and assignments, students will build upon knowledge and skills developed in the first two years of the didactic curriculum and the introductory hospital pharmacy practice experience. Students will continue to explore the concepts of professionalism and shared accountabilities for health care outcomes; formulate a personal philosophy of and approach to professional practice; expand drug and disease knowledge; and develop practical, critical thinking and life-long learning skills. This experience seeks to provide students with direct exposure to the dynamics of the community pharmacy workplace and to guide them to a realistic assessment of the challenges and opportunities that exist therein.

DESIRED COURSE OUTCOMES AND OBJECTIVES:

Activities of the community practice focus on clarifying distinguishing characteristics of community pharmacy practice and developing fundamental skills necessary to practice effectively in the community pharmacy setting. This experience will emphasize Understanding the scope of community pharmacy practice meeting individual patient needs and public health needs of the community

• Understanding and applying legal and ethical principles important to community pharmacy practice

• Gathering, storing and managing patient information in the community pharmacy setting


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• Participating in and managing medication use and medication therapy management (MTM)

Systems

• Communicating with professional colleagues and patients regarding the selection and/or use of

Non-prescription or prescription medications and medical devices and

• Understanding and managing operational aspects of the practice • Demonstrating mature and professional attitudes, habits and behaviors

DESCRIPTION OF TEACHING/LEARNING METHODS

• Experiential learning: applying knowledge, skills and attitudes learned in the classroom to patient care practice.

• Self-directed learning: students will engage with course content by independent work and selected course assignments.

RECOMMENDED LEARNING RESOURCES

• Students must have internet access and a UST email account • The Experiential Education Manual available on the school’s website at

http://pharmacy.ust.edu/programs/the-pharmd/office-of-experiential-education/experiential-education-manual. REQUIRED MATERIALS

• Short lab coat with UST name badge • Rx Preceptor at www.rxpreceptor.com is the rotation management software

system to track all pharmacy rotations and associated information. • Preceptors may require and/or recommend additional materials for their

rotations. • Students are expected to communicate with the preceptor regarding such

requirements prior to the rotation start date.

EXPECTATIONS FOR STUDENT ENGAGEMENT

• To receive full credit for this course, students are expected to attend and participate in all scheduled rotation activities; arrive on time; and remain until required activities have been completed or they are dismissed by their preceptor. It is expected that students will come to the rotation site with an open mind and respectful demeanor.

http://pharmacy.ust.edu/programs/the-pharmd/office-of-experiential

http://www.rxpreceptor.com


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• Student preparedness for topic discussions, patient case discussions, etc. is a critical element in this course. • The faculty and staff consider the preceptor-student relationship as collegial

and respectful. As more experienced, professional colleagues, preceptors generally view themselves as mentors in the student’s professional development. Students should expect preceptors to communicate expectations and instructions clearly and concisely.

• Students should also expect preceptors to provide them with relevant resources, activities, experiences and feedback to facilitate success in the curriculum and in practice. Preceptors are fully committed to fulfilling this responsibility and will work to ensure that each student has the opportunity to be successful. In return, preceptors expect students to behave in a professional, responsible, and ethical manner; demonstrate a positive attitude, enthusiasm for learning, and respect for themselves and others; be prepared for each session; be flexible and be accountable for their assigned responsibilities.

STUDENT ACTIVITIES AND ASSIGNMENTS

Students will work with preceptors to complete activities and assignments which will enable them to accomplish the objectives by the end of the rotation. Preceptors may utilize a learning contract and rotation calendar to organize the experience, to clearly communicate expectations, and to account for student requirements. Student projects are to be detailed by the preceptor, but it is expected that during the rotation the student will complete the activities described on the preceptor checklist / sign-off LATE ASSIGNMENT POLICY All assignments must be submitted by the designated deadline. Ramifications for late assignments will be at the discretion of the preceptor.

Evaluation of the Experience: These forms MUST be handed into the co-coordinator on or before the date specified in the Academic schedule:

• A training site issued certificate confirms the completion of required number of hours)

• Training notebook. • Evaluation forms:

o Student Performance Evaluation by the site coordinator o Student Performance Evaluation by the college coordinator o Site Evaluation by student o Training Evaluation by the student


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The grades will be distributed as follows: Item Grade 1 Completion of required hours 20 2 Evaluation of site coordinator 15 3 Evaluation of college coordinator 15 4 Notebook 25 5 Oral Examination 25 Total 100 Attendance: Attendance is mandatory for credit to be received. Students are expected to be punctual and to adhere to the scheduled times arranged with the site coordinator. If for any reason the student is not able to fulfill this commitment the site coordinator is to be contacted and alternative arrangements are to be made to complete the course requirements.


Faculty of Pharmacy


Professional Skill V



Department offering the course: - Pharmaceutical Sciences

Academic year / Level 4th year/ 1st semester


A- Basic Information Title: Professional Skills V Code: BPH21 Credit Hours: 1 hr Lecture: 14 Tutorial: Practical: - Total: 14


1 – Course Description: The course includes the activities of the community pharmacist in processing prescription, care of patients or clinical pharmacy, monitoring and utilization, small-scale manufacture of medicines, responding to symptoms of minor ailments (OTC drug), informing health care professionals and the public health promotion. Overall Aims Of Course 1. Provide the student with roles of community pharmacist 2. Describe and define a Community Pharmacy. 3. Explain the difference between business and professional services. 4. Describe the activities carried out by a Community Pharmacy. 5. Define and describe the social aspects of pharmacy

2- Intended Learning Outcomes Of Course (ILO’s) a. Knowledge and understanding:

a.1. Explain the roles of community pharmacist. a.2. Enumerate the non-prescription drugs. a.3. Understand the difference between business and professional services.

b. Intellectual Skills b.1 Identify the drug manufacturing relating problems and solve

b.2 Apply in practice setting the knowledge and understanding required to meet the needs of patient and other health professionals

c. Professional And Practical Skills

c.1 Able to dispense the drug prescription. c.2 Able to manage the drug adverse effect or drug interaction.

b. General and transferable skills

d.1 Interact effectively with patients, the public and health professionals. d.2 Reflect on the use of communication skills in counter prescribing.


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d.3 Critically analyze published literature 3- Contents

4– Teaching and Learning Methods 4.1- Lectures 4.2- Tutorials 4.4- visiting to community pharmacies

5- Student Assessment Methods To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. Weighing of assessments:

Topics No. of hours

Lecture Tutorial/ Practical

• objectives of community pharmacy • Distinguishing characteristics of a community pharmacy. • The pharmacist and patient's behaviour relationship. • Activities of a community pharmacy.

3 3

Non-prescription drugs: • Introduction • Types

1 1

• Community pharmacy organization • Structure of retail and wholesale drug store- • Types of drug stores and design • Legal requirements for establishment • Maintenance of drug store • Dispensing of proprietary products • Maintenance of records of retail and whole sale • Medication distribution system

3 3

• An introduction to Pharmaceutical care • Meeting the pharmaceutical care needs of specific populations 2 2

• Measuring and regulating medicines use o Adverse drug reactions and drug interactions o Health economics

3 3

• Health, illness and medicines use - Inequalities in health and health care - The supply and consumption of over the counter drugs -Promoting health

-Compliance, adherence and concordance

2 2

Total hours 14 14


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a First test 20%

b Second test 20%


6- List of References 6.2- Essential Books (Text Books)

Handbook of Non-Prescription drugs 6.3- Recommended Books

Pharmaceutical Practice, Winfield, 4th edition


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Therapeutics II

A-BASIC INFORMATION

Title: Therapeutics II Code: BPH43

Credit hours: 2 Lecture: 28 hrs

Tutorial: within practical classes Clerkship:

Academic year/ Level: Fourth year, Second Semester Total: 28



The course deals with the study of the different diseases and selection of study cases. The course also includes the role of the clinical pharmacist in providing pharmaceutical health care to the patient.


L- Giving knowledge about the patho-physiology of disease.

M- Explain the symptoms and complications of the diseases.

N- Analysis treatment aims and algorithms, drug interactions, dose calculations, side effects of drugs.

O- Recognize the safety of drugs in special groups like children, elderly and pregnancy.

P- Describe the appropriate lifestyle modifications, patient awareness and counseling.

Q- Solve the given case according to the correct therapeutic way.



A1- To acquire understand the principals of, patho-physiology, symptoms and complications that relevant to diseases.



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A6- To get knowledge about recent researches, articles and advanced studies on drugs treating many diseases











D1- Interact effectively with patients, the public and health care professionals; includes communication both written and oral.



D4- Behave with an ethical attitude and approach.


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3- CONTENTS:

Note: 3 clerkship hours equal one credit hour


4.1 Lectures

No. of Hours/week Credit Hours Lecture Title Clerkship Lecture

3 3 ٤ Infectious diseases Tuberculosis + Cases

3 3 ٤ Bacterial infections

3 3 ٤ Blood diseases Anemia

3 3 ٤ Leukemia + Hemophilia + Cases

3 3 ٤ Tumors Brain tumors + Cases

3 3 ٤ Breast cancer

3 3 ٤ Neurological diseases Epilepsy + Parkinson’s disease + Cases

3 3 ٤ Alzheimer’s disease + Depression + Cases

3 3 ٤ Bronchial Asthma

3 3 ٤ Acute Asthma ttt + Case study

3 3 ٤ Chronic obstructive pulmonary disease

3 3 ٤ Treatment of COPD + Case study

3 3 ٤ Urinary system Acute renal failure (ARF) + Case study

3 3 ٤ Chronic renal failure (CRF) + Case study

42 56 Total


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Computer, data show, white board, marker, OHP.




a First test 20%

b Second test 20%




6.2 Textbooks:

Textbook:




Patient-Focused Approach 7th edition 2009 6.3 Websites in international network (internet).


Faculty of Pharmacy


Integrated Case- Based Learning II

A-BASIC INFORMATION

Title: Integrated Case- Based Learning II Code: BPH47

Credit Hours: 1hour Lecture: -

Tutorial: 2 hours Clerkship: -

Academic year/ Level: Fourth year, Second Semester Total: 28



The course provides opportunities for the practice of medical cases and scenarios to emphasize the concept of clinical pharmacy with the focus on the systems covered in Overall Aims of Course:

R- Explain the symptoms and complications of the diseases.

S- Analysis treatment aims and algorithms, drug interactions, dose calculations, side effects of drugs.

T- Recognize the safety of drugs in special groups like children, elderly and pregnancy.

U- Describe the appropriate lifestyle modifications, patient awareness and counseling.

V- Solve the given case according to the correct therapeutic way. Therapeutic II simultaneously.






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3- CONTENTS: Tutorial Credit Hours Tutorial Title

2 1 Gastrointestinal tract Peptic ulcer Cases

2 1 Gastro-esophageal reflux disease Cases

2 1 Cardiovascular tract

Hypertension (HTN) Cases


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Note: 2 Tutorial hours equal one credit hour


Tutorial & Group-based discussion


CI. Assignments، in class group work, presentations and examinations.

5.1 Assessment schedule:

Assessment Time

First test Week 6

Second test Week 12

2 1 Continued HTN Cases

2 1 Coronary Heart Disease(CHD) Cases 2 1 Continued CHD Cases study

2 1 Congestive heart failure (CHF) Cases

2 1 Arrhythmias Cases study

2 1 Thyroid disorders

Hypothyroidism Cases study

2 1 Hyperthyroidism Cases study

2 1 Parathyroid disorders

Hypo- & Hyperparathyroidism Cases study

2 1 Pancreas disorders

Diabetes mellitus (DM) Cases study 2 1 DM continued Cases study

2 1 Rheumatic diseases Cases study

28 14 Total


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Final written exam. Week 14

5.2 Weighing of assessments:


a First test 20%

b Second test 20%

c Activities 10%

d Final test 50%

Total 100%



6.2 Textbooks:

Textbook:




Patient-Focused Approach 7th edition 2009 6.3 Websites in international network (internet).


Faculty of Pharmacy


Drug Delivery Systems Programme(s)on which the course is given: Bachelor of Pharmacy Major or minor element of programmes Faculty offering the programme: Pharmacy Department offering the course: Pharmaceutical Sciences Academic year/Level: Fourth year- Second semester Date of specification approval: / / A-BASIC INFORMATION Title: Drug Delivery Systems Code: BPH55 Credit hours: 2 Lecture: 28 hrs Tutorial: within classes Practical: - Total: 28 B-PROFESSIONAL INFORMATION Course description: This course outlines different hot topics in the field of drug delivery. The challenges, rationale, and remedy for drug delivery issues are covered in this graduate-level course. Overall aim of course: This course will introduce the students to the rationale, importance, and concepts of controlled delivery systems and drug targeting. Several novel drug delivery systems and their mechanisms of controlling the drug release will be discussed throughout the course. The different factors which can affect the drug release pattern and the drug absorption at site of release will be emphasized. 2-Intended Learning Outcomes of course (ILOs) A-Knowledge and Understanding: The student should be able to:

3. Define the different types of drug delivery systems. 4. Describe the various procedures used in developing such systems. 5. List the different factors affecting drug release from different systems. 6. Mention the different methods of site-specific drug targeting.


3. Compare between conventional dosage forms and novel drug delivery systems.


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4. Differentiate between different types of drug delivery systems. 5. Recognize the drugs which are suitable to be formulated in novel drug delivery

systems. 6. Conclude the possible drug delivery systems to be used for the modified release

of certain drugs C-Professional and practical skills: The student should be able to:

5. Compound several drug delivery systems. 6. Overcome different manufacturing problems. 7. Explain which novel drug delivery systems match certain biological needs and

drug properties. D-General and transferable skills: The student should be able to: d.7 Demonstrate critical thinking, decision making, synthesis and interpretation of

pharmaceutical information, and responsibility. d.8 Obtain required scientific information from available sources. 3-Contents: No Topic Theoretical Practical 1 Fundamentals of Controlled Release Drug Delivery ٤ - 2 Oral controlled drug delivery systems 4 - 3 Transdermal drug delivery systems 2 - 4 Polymeric drug delivery systems 6 - 5 liposomes ٢ - 6 Gastro-retentive systems 2 - 7 Microencapsulation 2 - 8 Targeted drug delivery systems 2 - 9 Protein & peptide drug delivery system 2 - 4-Teaching and learning methods

• Lectures (Tools: board, overhead projector, pc and data- show projector). • Assignments (journal club discussions).

5-Student assessment method To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. Weighing of assessments:


Faculty of Pharmacy



a First test 20%

b Second test 20%


6-List of references Textbook: Novel drug delivery system – Marcel Dekker N.Y. Second Edition, Revised and Expanded by Yie W. Chien. Vol- 50. Supplements:

• Controlled drug delivery system – Vicent H.L., second edition. • Controlled and novel drug delivery systems – N.K. Jain, 2011. • Drug Delivery; principles and applications, Wang, Siahaan, and Soltero, 2005. • Deign of controlled release drug delivery systems, Li and Jasti, 2006.

7-Facilities required for teaching and learning Lecture rooms, computers, data show, library, and internet access. Course coordinator: Head of department: Dr. Khaled Al-Tahami


Faculty of Pharmacy


All Departments in University

All Programs

Course Name (Course code): Research Methodology (UST10)

Second Semester, Fourth Year

COURSE SYLLABUS


Faculty of Pharmacy


I. COURSE INFORMATION [معلومات عن المقرر]

1. COURSE TITLE: مناھج البحث العلمي عنوان المقرر:2. COURSE CODE: UST10 : رمز المقرر 3. CREDIT HOURS: 2 credit hours 4. PREREQUISITE: رموز المتطلبات القبلیة للمقرر 5. COREQUISITE: BPH56 6. PREPARED BY: اسم الشخص المعد للتوصیف 7. APPROVED BY: اسم الجھة المعتمدة للتوصیف

II. COURSE DESCRIPTION توصیف المقرر

تنمیة إلىیتناول مقرر مناھج البحث العلمي مجموعة من الموضوعات الدراسیة التي تھدف االتجاھات لدى المتعلم تجاه البحث العلمي، وتعمل على إكسابھ مجموعة من المعلومات والمعارف

مناھج البحث، وطرق اختیار المشكلة، وصیاغتھا، وخطوات توضیحھا، العلم والمعرفة، وحول إكساب المتعلم مجموعة من إلىالنظریة والمیدانیة، كما یھدف ، وأدوات جمع المعلومات والعینات

المھارات المتعلقة بتصمیم أدوات البحث، وكتابة التقریر النھائي للبحث، وتوثیق المراجع توثیقا صحیحا.

III. COURSE OUTCOMES مخرجات المقرر

-المقرر أن یصبح قادرا على أن:یتوقع من المتعلم بعد إنھاء دراستھ لھذا یظھر معرفة بالعلم والمعرفة والبحث العلمي. - یناقش أھمیة البحث العلمي. - مناھج البحث العلمي. یوضح - .، واختیارھامھارات تحدید مشكلة البحث، وصیاغتھا یكتسب - .بحثیةفروض یصیغ - یكتب خطة بحثیة. - یوضح العینات، وطرق اختیارھا. - .المعلوماتجمع صمم أدوات ی - تقریر بحث. یكتب - المراجع توثیقا صحیحا.المصادر ووثق ی - .بصورة صحیحة المكتبات العامة والمصادر والمراجع یستخدم - یوضح خطوات البحث العلمي. - مراجعة الدراسات السابقة. یحدد كیفیة - یستشعر أھمیة البحث العلمي. - المختلفة.یحرص على االستفادة من البحث العلمي في شؤون حیاتھ -


Faculty of Pharmacy


IV. COURSE TOPICS الموضوعات الرئیسة في المقرر

رقم الوحدة

عدد العناوین الفرعیة العنوان الرئیس الساعات

مالحظات

األولى

العلم والمعرفة البحث العلميو

تعریف العلم. • تعریف المعرفة. • أھداف العلم. • مصادر العلم والمعرفة. • تعریف البحث العلمي. • العلمي.أھمیة البحث • أغراض البحث العلمي. • ضوابط البحث العلمي. •

٤

مناھج البحث الثانیة العلمي

تعریف المنھج في اللغة. • تعریف المنھج في االصطالح. • تعریف منھج البحث العلمي. • المنھج الوصفي: •

مفھوم المنھج الوصفي. - أھداف المنھج الوصفي. - خصائص المنھج الوصفي. - خطوات المنھج الوصفي. - أنماط األبحاث الوصفیة: -

البحث المسحي. -١ .االرتباطيالبحث -٢ المقارن. البحث السببي -٣ تحلیل المضمون. -٤ دراسة الحالة. -٥

-المنھج التجریبي: • تعریف المنھج التجریبي. - خصائص المنھج التجریبي. - خطوات المنھج التجریبي. -

-المنھج التاریخي: • تعریف المنھج التاریخي. - خصائص المنھج التاریخي. - خطوات المنھج التاریخي. - أدوات المنھج التاریخي. -

٤


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إعداد خطة الثالثة البحث

اختیار الموضوع وتحدید • العنوان.

عناصر خطة البحث: • مقدمة البحث. - مشكلة البحث وصیاغتھا. - أسئلة وفروض البحث. - أھداف البحث. - أھمیة البحث. - حدود البحث. - مصطلحات البحث. - إجراءات البحث. -

٤

العینة العشوائیة (االحتمالیة): • عینة البحث الرابعة العینة العشوائیة البسیطة. - العینة العشوائیة المنتظمة. - العینة العشوائیة الطبقیة. - العینة العشوائیة العنقودیة. - العینة العشوائیة المزدوجة. -

العینة غیر العشوائیة (غیر • االحتمالیة):

العینة المالئمة. - العینة العمدیة: -

الحكمیة.العینة .١ العینة الحصصیة. .٢

٤

أدوات جمع الخامسة المعلومات

االستبیان. • المقابلة. • المالحظة. • االختبارات. •

٤

استخدام السادسةالمكتبة

والمصادر عوالمراج

استخدام المكتبة • مفھوم المكتبة. - تنظیم المكتبة الحدیثة. - التصنیف في المكتبة. - فھرس البطاقات. - والمعلومات:مصادر البیانات • مصادر ثانویة. - مصادر أساسیة. -إسھام اإلنترنت في مجال •

البحث العلمي.

٢

٢ امتحان نصفي • امتحان نصفي


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تعریف التوثیق العلمي. • التوثیق العلمي السابعة التوثیق في متن البحث. • التوثیق في المصادر والمراجع: • التوثیق العلمي للكتب. - العلمیة.التوثیق العلمي للرسائل -التوثیق العلمي للدوریات -

والمجالت العلمیة. التوثیق العلمي لإلنترنت. -

٢

خطوات إعداد الثامنة البحث العلمي

توضیح ماھیة المشكلة. - مراجعة الدراسات السابقة. -تصمیم البحث وتحدید خطواتھ -

اإلجرائیة. اجمع المعلومات وتحلیلھ -

وتفسیرھا.، ھملخص البحث وأھم نتائج -

ةوتوصیاتھ، وبحوث مقترح للدراسة.

٤

V. RESOURCES: المراجع

Text Book الكتاب األساسي للمقرر ) ، صنعاء، جامعة العلوم والتكنولوجیا.١): مناھج البحث العلمي ،ط (٢٠١١عبد الغني محمد اسماعیل العمراني ( .١

Supplement (s) المراجع اإلضافیة والداعمة

)، الكویت، وكالة المطبوعات عبدهللا حرمي.٧البحث العلمي ومناھجھ، ط( ): أصول١٩٨٤أحمد بدر ( .٢ )، الكویت، وكالة المطبوعات.٣): مناھج البحث العلمي، ط(١٩٧٧عبد الرحمن بدوي ( .٣ ): أصول البحث العلمي، مصر، االسكندریة، مؤسسة شباب الجامعة.٢٠٠٣حسین عبد الحمید رشوان ( .٤، االردن، ھعدس، وكاید عبد الحق (د ت): البحث العلمي.. مفھومھ، أدواتھ، أسالیبذوقان عبیدات، عبد الرحمن .٥

عمان، دار مجدالوي للنشر والتوزیع. )، الریاض، مكتبة العبیكان.٢): دلیل الباحث في العلوم السلوكیة، ط(٢٠٠٠صالح بن حمد العساف ( .٦ كتابة البحث العلمي، صنعاء، دار الكتاب الجامعي.): دلیل الطالب الى ٢٠٠٧عبد الغني محمد اسماعیل العمراني ( .٧ )، صنعاء، األمین للنشر والتوزیع.٢): طرق البحث، ط (٢٠٠٩منصور محمد اسماعیل العریقي ( .٨): مناھج البحث في التربیة وعلم النفس، مصر، القاھرة، دار ٢٠٠٢جابر عبد الحمید جابر، وأحمد خیري كاظم ( .٩

النھضة العربیة.


Faculty of Pharmacy


Biostatistics

Faculty offering the programme: Pharmacy

Department offering the course: community medicine

Academic year / Level: 4th – second semester

Date of specification approval:

A- Basic Information Title: Biostatistics Code: BPH56 Credit Hours: 2 Lectures: 28 hrs Practical Total: 28 hrs


1 – Course Description:

This course is dealing with principles of quantitative techniques as applied to assays and studies in research. The measures of tendency as well as the measures of dispersion will be covered in this course.


This course aims to familiarize pharmacy students with the basic statistical procedures which are required in pharmacy studies.

2 – Intended Learning Outcomes of Course (ILOs) a- Knowledge and Understanding: a.1. define in words and formula basic statistical procedures a.2. Describe the nature of data a.3. Understand picture graphs a.4. Describe simple methods for data collection and presentation. a.5. Describe the fundamentals of probability and test of significance

b- Intellectual Skills

b.1 Recognize the structure of the data in a variety of standard situations and define the problem to be solved in statistical terms;

b.2 Select and apply appropriate statistical methods, and interpret the results; b.3 Construct a table containing relative frequencies & cumulative percent. b.4 Discuss major techniques of data collection ,presentation and analysis b.5 Estimate a population mean for a large & small sample

c- Professional and Practical Skills

c.1 Present data by mean of various graphical methods . c.2 Carry out a critical evaluation of an analytical method, c.3 Find probabilities and values for the standard normal distribution c.4 Find probabilities and values for nonstandard normal distributions


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d-General and Transferable Skills

d.1 Be familiar with central tendency & description d.2 Use appropriate statistical methods of data analysis; d.3 Interpret numerical information and results of statistical analyses; d.4 Select and apply appropriate statistical tools to perform a range of inferential

analyses d.5 Produce and interpret statistical control charts for variation, mean and attributes d.6 Utilize computers in conducting research

3-Contents:

5– Teaching and Learning Methods

4.1 Lectures using data show and board and marker. 4.2 Group Discussion

6 - Student Assessment Methods To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. Weighing of assessments:


a First test 20%

b Second test 20%

c Assignments 10%

Topic Hours Lec. 1.Introduction to course: Aims, contents, assessment ,reference of Course Biostatistics: Definition, General terms, Uses, type & sources of data.

2

2. Elementary Statistical Method, Charts, Diagram, Tabulation 2 3. Measures of Central Tendency 2 4. Measures of dispersion 2 5. Sampling &sample size 2 6. Normal distribution&z-test 2 7. Tests of significance § Definition, steps ,hypothesis § Chi square § T-test § ANOVA § Correlation and regression § SPSS

2 2 4 2 2 4

Total 28


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d Final test 50% Total 100%

6- List of References

6.1- Course Notes PowerPoint presentation 6.2- Essential Books (Text Books):

Danial .w. (1998).Biostatistics: A foundation for analysis in health science .(7th ed )New York

6.3- Recommended Books Chap t. Le(2003) introductory biostatistics. Wiley & sons, inc. New jersey

6.4- Periodicals, Web Sites, … etc

http://www.statistics.com/

7- Facilities Required for Teaching and Learning Data show, board and markers

Course Coordinator: Dr Mahdi Alkarawany

Head of Department: Dr Abdulla Abdu Almikhlafy Date: / /

http://www.statistics.com/


Faculty of Pharmacy


Pharmacokinetics Program (s) in which the course is given: Bachelor of Pharmacy Major or minor element of programmes Department offering the programme: Pharmacy Department offering the course: Pharmacy Academic year/Level: Fourth year- Second Semester Date of specification approval: A-BASIC INFORMATION Title: Pharmacokinetics Code: BPH57 Credit hours: 2 Lecture: 28 hours Tutorial: within lecture classes Practical: Total: 28 B- Professional Information

1- Course Description: This course covers the study of the kinetics of drug absorption, distribution, metabolism and elimination of the drug in the body. It includes compartmental models, volume of distribution, mathematical review, and kinetics of pharmacological effect, multiple dosing, renal and hepatic excretions and dosage regimen adjustment. Overall Aims of Course: A- To get an insight into the world of pharmacokinetics B- To be familiar with pharmacokinetics such as volume of distribution, distribution coefficient, and different order modeling C- To understand the basics, importance, and applications of compartment model in IV and oral routes D- To learn the Clearance concept, mechanism of renal clearance, clearance ratio, and determination of renal clearance E- To understand Hepatic elimination of drugs, first pass effect, extraction ratio, hepatic clearance, biliary excretion, extrahepatic circulation E- To be introduced to non-linear pharmacokinetics, dosing options, and monitoring

2- Intended Learning Outcomes Of Course (Ilos)


A1- Understanding the use of pharmacokinetics to direct the appropriate administration of drugs, particularly intravenous infusion and multiple dose administration. A2- Understanding the theoretical and practical issues of assessment of drug bioavailability and bioequivalence. A3- Ability to estimate pharmacokinetic parameters used in clinical pharmacokinetics and biopharmaceutics using plasma and urine drug level data. A4- Ability to correlate renal functions to dose and to perform needed calculations to account for any renal problems A5- Describe the significance and impact of the first-pass effect and hepatic clearance after oral administration. A6- Learn the concepts needed for drug monitoring and dosing especially for children and elderly


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B-Intellectual skills: Ability to use empirical pharmacokinetic models to devise and optimize dosage regimens. C- Professional and practical skills: To acquire skills to carry out pharmacokinetics calculations needed for dose estimation and adjustment D-General and transferable skills: To have the ability to deal with problems and to come up with solutions during dosage form development and manufacturing. 3-Contents: 4-

Teaching And Learning Methods 4.1 Lectures Computer, data show, white board, marker. 4.2 Practical NA

Lecture Title

Lecture

2 Introduction and definitions

2 Pharmacokinetics of drug administered by intravenous route:

- Pharmacokinetics Model - One compartment open model

2 - Two compartments open model

2 - Multiple dosing in IV injection - IV infusion

2 Pharmacokinetics of drug administered by oral route:

- Pharmacokinetics of drug absorption - Determination of Ka

2 - Extra-Vascular multiple dose administration

2 - Models of oral absorption

2 Renal excretion and clearance:

2 Renal excretion and clearance…continued 2 Hepatic clearance and elimination 2 Hepatic clearance and elimination… continued

2 Selected topics:

- Therapeutic drug monitoring - Determination of doses

2 - Dosing of drugs in infants and elderly

2 - Nonlinear pharmacokinetics - Protein binding of drugs

٢٨ Total


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5- Student Assessment Method To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. Weighing of assessments:


a First test 20%

b Second test 20%


6- List Of References 6.1 Course notes provided to the students 6.2 Textbooks: Textbook:\ Applied biopharmaceutics & pharmacokinetics by Leon Shargel, Susanna Wu-Pong, Andrew B. C. Yu Supplement: Biopharmaceutics and Clinical Pharmacokinetics [Book] by Milo Gibaldi 6.3 Websites in international network (internet). 7- Facilities Required For Teaching And Learning Lecture rooms, computers, data show, library, and internet access.


Faculty of Pharmacy


Toxicology

Program (s) in which the course is given: Bachelor of Pharmacy Major or minor element of programmes Department offering the programme: Pharmacy Department offering the course: Pharmacy Academic year/Level: Fourth year- Second Semester Date of specification approval: A-BASIC INFORMATION Title: Toxicology Code: BPH58 Credit hours: 2 Lecture: 28 hours Tutorial: within lecture classes Practical: - Total: 28



This course includes general principles in toxicology, toxic manifestations and antidotal measures

of environmental poisons (air pollutants, industrial poisons, animal poisons, food poisoning etc...)

and drugs.


Students are expected to develop awareness for the adverse effects of chemotherapeutic agents

and drugs, methods of toxicity, signs and symptoms of toxicity and treatment of toxicity

symptoms.

2- Intended learning outcomes of course (ILOs)



Understand the basic background of medical, occupational, and environmental toxicology.



b.1 Discuss and analyze the general classification of toxic compounds.

b.2 Discuss and analyze the toxic effects of compounds on human.



c.1 Manage the poisoned patient.

c.2 Deal with poisons.

c.3 Work in hospitals and poisoning centres.


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At the end of the course the student should be aware about:

d.1 The importance of continuous self-study of drugs.

d.2 Coordinate the basic and the practical knowledge of toxicology.

3- Contents:

Lectures

No. Title Hours

1 Introduction to Occupational Environmental & Medical Toxicology. 2

2 ED50, TD50, TI, and LD50, class of chemicals based on LD. 2

3 Air pollutants 2

4 Solvents, insecticides, envi. Pollutants, ABCD rule. 2

5 Management of the poisoned patient. 2

6 Antidotes, history, physical exam, vital signs. 2

7 Continuation of vital signs, eyes, mouth, skin. 2

8 Midterm exam 2

9 Nervous system, laboratory exam. 2

10 Gases, electrolytes, kidney, ECG, x-rays. 2

11 Chelating agents. 2

12 Harmful effects of drugs on organs. 2

13 Allergic reactions to drugs. 2

14 Free radicals and antioxidants. 2

Total 28

4- Teaching and learning methods

Lectures



To evaluate the understanding and ability to develop required skills of students, in midterm or final exam.


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Weighing of assessments:


a First test 20%

b Second test 20%


6- References

Textbook:

• Richard C Dart, Medical toxicology, 2004, 3rd Edition, Lippincott, USA.

Supplemets:

• Bertram G Katzung, Basic and Clinical Pharmacology, 2009, 11th Edition, Mc

Graw Hill, Lange.

• Rang HP, Dale MM, Ritter JM and Flower RJ Pharmacology, 2007, 6th Edition,

Churchill Livingstone.

• John A Timbrell, Introduction to toxicology.


White board, data show, textbooks.

Course coordinator:

Head of departement:


Faculty of Pharmacy


Pharmacoepidemiology and Pharmacoeconomics

Course Specifications Program (s) on which the course is given Major or Minor element of programs Department offering the program: Faculty of Pharmacy. Academic year / Level 4th level, second semester Date of specification approval

A-Basic Information Title: Pharmacoepidemiology and Pharmacoeconomics Code: BPH59

Credit Hours: 1 hrs/ week Lecture: Lecture: 1 hrs/week/semester Total: 14 hours B- Professional Information


The concepts of pharmacoepidemiology and the science of safety are discussed throughout the course as important factors in drug safety, drug effectiveness, and outcome assessment and regulatory decision-making.This course introduces students to the principles of pharmacoeconomics for use in analyzing the economic impact of pharmaceuticals on health care systems and pharmacoeconomic analysis and costing of drugs and services. Overall Aims of Course: 1. Explain how pharmacoeconomics distinguishes itself as a unique “toolbox” for use in analyzing the economic impact of pharmaceuticals on health care systems. 2. Explain the different perspectives influence pharmacoeconomic analysis and costing of drugs and services. 3. Explain Pharmacoepidemiology and the Science of Safety play an important role in drug safety, drug effectiveness, and outcome assessment and regulatory decision-making. 2- Intended learning outcomes of course (ILOs)


A1. To provide the student with knowledge and understanding a basic background of

pharmacoepidemology and pharmacoeconomics.

A2. The student will be able to recognize Pharmacoepidemiology and Pharmacoeconomics issues and able to address the effects of medication use in populations A3. The student able to understand the economic, institutional and policy aspects of the markets for health care and health care technologies



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B1. The student able to apply skills to the solution of real life problems by developing research questions, conducting research and sharing research findings with the scientific community. B2. The student able to recognize drug safety issues and develop appropriate strategies to optimize the benefit/risk ratio of the product involved. C- Professional and practical skills:

C1. Is expected to be able to write a study protocol in a clear, simple, and parsimonious manner, responsive to the question at hand, and proposing a methodological sound design. C2. Skill to to derive the relevant cost and revenue streams needed to conduct a

pharmacoeconomic analysis.


D1. Acquire skill to work in pharmaceutical companies and pharmacy benefits management, and government public health, medicine, and other related sectors. 3- Contents:

Lecture No. of hours

Topic No

1 1 introduction of terminology; review of major methodologies

١

1 1 Basic principle of clinical epidemiology relevant to pharmacoepidemiology studies.

٢

1 1 Role of pharmacoepidemiology in the health care system and academic

٣

١ ١ Case-control, nested case-control studies; cross-over designs studies and matching in pharmacoepidemiology

٤

١ ١ Large Data Base Research Student discussion of data source selection

٥

1 1 Drug Utilization studies ٦ 1 1 Evaluating and improving physician prescription ٧ ١ ١ Midterm exam ٨ 1 1 Definition of pharmacoeconomics. Role and

importance of pharmacoeconomic analyses in drug management

9

1 1 Basic types of pharmacoeconomic analyses 10 1 1 Cost Effectiveness and Cost Minimization 11 1 1 Cost Benefit and Cost Utility 12 1 1 Pharmacoeconomics in Drug Development 13 1 1 Quality of Life Assessment 14


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14 14 Total

4- Teaching and learning methods

Lectures




Assessment Weight Description a First test 20%

b Second test 20%


6- Textbooks:

1. Tilson HH, Chan KA. Editors. Pharmacoepidemiology and Therapeutic Risk Management. Harvey Whitney press, Cincinnati, 2008.

2. Drummond MF, McGuire A. Economic evaluation in health care; merging theory with practice. Oxford University Press, 2001


White board, data show, textbooks.

Recommended text book:

1. - Drummond MF, O’Brien B. Methods for the Economic Evaluation of Health Care Programmes. 2nd Edition. Oxford University Press. New York, New York. 1997.

2. Strom BL, Kimmel SE. Textbook of Pharmacoepidemiology. West Sussex, England: John Wiley & Sons Ltd, 2006.

Website:

International Society for Pharmacoepidemiology website. http://www.pharmacoepi.org

Public Health

http://www.pharmacoepi.org


Faculty of Pharmacy


Program (s) in which the course is given: Bachelor of Pharmacy Major or minor element of programmes Department offering the programme: Pharmacy Department offering the course: Pharmacy Academic year/Level: Fourth year- Second Semester Date of specification approval: A-BASIC INFORMATION Title: Public Health Code: BPH60 Credit hours: 1 Lecture: 14 hours Tutorial: within lecture classes Practical: - Total: 14


1 – Course Description:

This course provides pharmacy students with the basic information about concept of health, disease prevention, environmental health, and occupational health.


The students are expected to recognize and apply the concepts of public health taught throughout the course.

2 – Intended Learning Outcomes of Course (ILOs):

By the end of this course each student, should be able to:

a- Knowledge and Understanding: a.1. Understand the concept health and disease a.2. Describe the level of prevention of diseases a.3. Identify epidemiological triad ( agents , host & Environment ) : definition , types

and relation to health a.4. Define epidemiology of occupational & chronic disease a.5. Recognize aims ,types; methods& barriers of health education a.6. Define the nature, health effects and sources of environmental risks.

b-Intellectual Skills

b.1 Define the role of the PHC physician in the prevention and control of non-communicable diseases

b.2 Describe the programs for prevention and control of occupational health &common chronic diseases

b.3 List the health education messages pertinent to a healthy life style, prevention, and control

b.4 Describe how to communicate a message skillfully (knowledge)


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b.5 Describe the different heath education methods and materials, stating their characteristics, utilities, and limitations

b.6 Identify environmental risk factors c- Professional and Practical Skills

c.1 Use standard parametric measure. c.2 Identify trends in health and disease including epidemiological causes of high

prevalence c.3 Application of health education program. c.4 Establish a good supervisor/ subordinates relation

d- General and Transferable Skills

d.1 Application of public health programs or policies; d.2 Apply appropriate health promotion, disease prevention and control measures to

identified priority communicable diseases

3- Contents

Subject Topic

Hours

Lec.

Publ

ic h

ealth

Concept of Health& disease : • Definition of health, public health • Dimension, indicators & determinant of health • Natural history of diseases & level of prevention

3

Epidemiological triad : • Agent : def , types & properties • Host : def, factors • Environment : Environmental Sanitation: Concepts and definitions;

Hazards and risks and sanitation; Types of pollutants; Food and water safety; Environmental risk

assessment and management

4

Epidemiology: • Def & uses

2

Occupational health : • Definition • Occupational hazards • Prevention & control

3

Chronic diseases : • Definition • Risk factors

1

Health Education 1


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• Definition, objectives , types & methods • Health Education Programs & how to implement

Total 14

4– Teaching and Learning Methods 4.1-Lecture 4.2-Discussion. 4.3- Assigned reading.

5- Student Assessment Methods To evaluate the understanding and ability to develop required skills of students, in midterm or final exam. Weighing of assessments:


a First test 20%

b Second test 20%


------------------------------------------ 6- List of References

6.1- Course handouts 6.2- Textbook: Park,S Textbook Of Preventive And Social Medicine Supplements: Essentials of Public Health: L. J. Donaldson, R. J. Donaldson

7- Facilities Required for Teaching and Learning Overhead .

Course Coordinator: Dr Mahdi Alkarawany Head of Department: Dr Abdullah Almikhlafy

Date: / 11 / 2010


Faculty of Pharmacy


Structured Practical Experiential Program II Programme(s)on which the course is given: Bachelor of Pharmacy Major or minor element of programmes Department offering the programme: NA Department offering the course: Pharmaceutical Sciences Academic year/Level: Fourth year-Second semester Date of specification approval: / / A-BASIC INFORMATION Title: Structured Practical Experiential Program II Code: BPH52 Credit hours: 2 Lecture: - Practical: 30 real time supervised training at a pharmaceutical industry site Total: 2 B-PROFESSIONAL INFORMATION Course Description: Structured Practical Experiential Program II (SPEP II) is an experience and training program for Pharmacy students in their fourth year of the program. The course is a 2 credit hour course and consists of a total of 30 hours of pharmaceutical industry training in a pre-approved site. This course gives students opportunities to incorporate skills and competencies learned in the classroom into their professional practice. This training module aims to provide the students with the basic skills needed in the field of pharmaceutical industry. Through it is not feasible to make sure that the student/trainee acquire all practical abilities, the student will gain appreciation for pharmaceutical industry and its vast career options. Many of these skills will be addressed previously in the academic program in the lectures and laboratory of pharmaceutical technology. Students will polish their acquired skills and gain an overview on the real-life prospects of industry. The students will also develop professionalism, judgment, and skills needed to function in this setting. The students will observe and discuss the many roles of the pharmacist in the industry and participate in active learning to reinforce learning objectives. Course objectives: The objectives of this training are to provide pharmacy students with an opportunity to: 1. Get an insight on the layout and different processes carried out in pharmaceutical industry. 2. Practice in a professional manner during all interactions with pharmaceutical industry personnel 3. Learn, modify and apply skills involved in the various aspects of pharmaceutical industry.


Faculty of Pharmacy


Ability Outcomes: At the end of this training module, the student shall have the following abilities:

1. List the activities that the pharmacist performs in the field of pharmaceutical industry.

2. Explain the basic layout of a pharmaceutical plant. 3. Identify the type of records utilized at the site. 4. Observe the different aspects of Good Manufacturing Practice (GMP) and Good

Laboratory Practice (GLP). 5. Gain a prospective on the process of raw materials purchasing, quality control

test, and dispensing. 6. Identify the different processes involved in the production of different

pharmaceuticals. 7. Determine the different requirements for the packaging and storage of finished

products. 8. Outline the different procedures of quality control, quality assurance, and

validation. 9. Identify the different techniques and instruments employed in the research and

development (R&D) and quality control (QC) departments. 10. Students will demonstrate a high standard of professional behavior (i.e., adhering

to established work schedule, minimizing absences, respecting fellow trainees and facility workers)

11. Demonstrate effective communication skills in response to preceptors and site workers.

Each student is required to:

• Attend the scheduled debriefing session at the beginning of the training. This session is mandatory and critical to meeting the course objectives

• Complete a total of 30 hours of pharmaceutical industry training at a designated plant. The training should cover all of plant departments.

• Submit a training notebook at the end of the training reflecting the whole training experience in a daily report format.

• Perform a presentation describing his training experience. • Complete and submit all evaluation forms to the course co-coordinator on or

before the due date specified. • Behave in a professional manner at all times during the course of their rotation.

Students are also expected to wear appropriate, professional attire suitable to their experiential site

Evaluation of the Experience:


Faculty of Pharmacy


These forms MUST be handed into the co-coordinator on or before the date specified in the Academic schedule:

• A training site issued certificate confirms the completion of required number of hours)

• Training notebook. • Evaluation forms:

o Student Performance Evaluation by the site coordinator o Student Performance Evaluation by the college coordinator o Site Evaluation by student o Training Evaluation by the student

The grades will be distributed as follows: Item Grade 1 Completion of required hours 20 2 Evaluation of site coordinator 15 3 Evaluation of college coordinator 15 4 Notebook 25 5 Presentation 25 Total 100 Attendance: Attendance is mandatory for credit to be received. Students are expected to be punctual and to adhere to the scheduled times arranged with the site coordinator. If for any reason the student is not able to fulfill this commitment the site coordinator is to be contacted and alternative arrangements are to be made to complete the course requirements. Guidelines:

• Industrial pharmacy training is hosted by local pharmaceutical industry. Keep in mind that your attitude and interaction affect the image of your school and future training agreements with these factories. Follow the regulations of the establishments and remember that these businesses are investing a lot of effort in your training.

• Dress and act professionally. • Be attentive to what you are told and interact positively. Reading the theoretical

material prior to visits is always a must-do practice. • Every student should have a notebook for the training experience. This notebook

should be available for inspection by instructors upon request and will be graded.


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• Visit reports in training notebook should be filled immediately after the visit and should include:

o Date, time, and duration of the visit o Establishment where training took place o Objectives of the visit o Departments and production lines visited with a detailed description of the

machinery o Production steps and analytical methods carried out (or demonstrated)

during the visit including quality control assays.

Course coordinator: Head of department: Dr. Khaled Al-Tahami


Faculty of Pharmacy


Professional Skill VI

PROGRAMME(S) ON WHICH THE COURSE IS GIVEN



Department offering the course: - Pharmaceutics

Academic year / Level 4th year / 2nd semester



Title: Professional Skill VI Code: BPH22 Credit Hours: 1 hr Lecture: 14 Tutorial: Practical: - Total: 28


1 – Couse description: This course covers the development, functions, organization and administration of pharmaceutical services within the hospital. This course also deals with the pharmaceutical services offered to in-patients and out-patients. It includes drug distribution, I.V. admixtures, total parenteral nutrition, and dosage calculations. Emphasis is also given to design and manufacture of formulations for hospital use including their quality assurance and packaging. Overall aim of course: The student shall develop an understanding of the complete process of the drug distribution system, from the purchasing and receipt of drugs by the hospital including their administration to the patient. The resident shall also develop an understanding of an intravenous admixture service, including total parenteral nutrition and chemotherapy.

2 – Intended Learning Outcomes Of Course (Ilos)

a. Knowledge and understanding: a.1. Explain hospital organization/committee functions, interpret and enter

patient orders and prepare intravenous admixtures. a.2. Describe and demonstrate the steps involved in preparation of

intermittent and continuous infusions, total parenteral nutrition, and chemotherapy.

a.3. Understand steps involved in drug therapy monitoring demonstrate proper aseptic technique in IV admixture compounding

a.4. Demonstrate appropriate and accurate use of calculations in all aspects of intravenous admixture preparation

a.5. Describe all legal requirements and professional standards that pertain to the distribution and control of drugs in hospitals.

a.6. Demonstrate evidence of understanding of policies and procedures relating to distribution and administration of drugs to patients.


Faculty of Pharmacy


a.7. Explain the principles, advantages and disadvantages of the various types of drug distribution systems used in hospitals and their contribution to patient- focused pharmacy practice.

a.8. Describe the role of drug distribution as a component of the provision of pharmaceutical care.

a.9. State the benefits and limitations of using a profile for pharmacotherapy monitoring and drug distribution.

b. Intellectual Skills b.1 Calculate the medicine doses and dosage regimen. b.2 Interpret patient and clinical data, including patients records held within

practice settings. b.3 Interpret of prescription and other orders of medicines. b.4 Identify potential drug- related problems that could occur as result of the

hospital's distribution system and identify ways to prevent their occurrence.

b.5 Apply in practice setting the knowledge and understanding required to meet the needs of patient and other health professionals.

b.6 Interpret the appropriateness of medication order before preparing or permitting dispensing the patient dose.

c. Professional And Practical Skills c.1 Design and evaluate therapeutic regimens to optimize drug use. c.2 Interpret and process of medical orders. c.3 Dispense medicines, advice patients on correct and rational use of

medicines and cosmetics. c.4 Interpret patient scientific data to help evaluate and optimizing

prescribing in primary care. c.5 Counsel people on health matters c.6 Apply their knowledge to advice patients and other health care

professionals about safe and effective use of drugs and medicines. c.7 Unit dose Interpret/ check medication orders for completeness,

appropriateness, and accuracy c.8 Evaluate medication orders for drug allergy, interactions, and

contraindications according to specific patient profiles c.9 Identify real or potential drug-related problems through the use of

medication profiles and initiate appropriate action. c.10 Follow departmental procedures and pharmacy standards of practice to

insure the integrity of drugs dispensed within the hospital. c.11 Identify, document, evaluate and follow-up on medication errors, in

accordance with hospital policy. c.12 Effectively review, process and dispenses medication orders, according

to hospital policies and procedures, including formulary drugs, non-formulary drugs, restricted drugs, drugs within therapeutic interchange policy, investigational and special access drugs, narcotic and controlled drugs.

c.13 Label and document dispensing of all drugs, in accordance with the hospital’s policies and procedures.


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c.14 Accurately assess admixture solutions for appropriate concentrations, rate, compatibilities, stability, and storage

d. General And Transferable Skills

d.1 Communicate efficiently and effectively with patients and other healthcare professionals\

d.2 Reflect on the use of communication skills in counter prescribing. d.3 Critically analyze published literature.

Contents

Topic No. of hours Lecture Tutorial/

Practical Introduction

• Organization and Structure Organization of a hospital and hospital pharmacy

• Responsibilities of a hospital pharmacist • Pharmacy and therapeutic committee • Hospital formulary Contents, preparation and revision of hospital

formulary.

2 2

Drug Store Management and Inventory Control: • Organization of a drug store • Types of materials stocked • Storage conditions. • Purchase and Inventory Control - Principles - purchase

procedures - Purchase order - Procurement and stocking

2 2

Inpatient pharmacy services • Dose adjustment. • Intravenous admixture (TPN). • Therapy drug monitoring (TDM)

Outpatient pharmacy services

5 5

Drug Distribution Systems in Hospitals: • Outpatient dispensing - methods adopted. • Dispensing of drugs to inpatients. • Types of drug distribution systems. • Charging policy – labeling • Dispensing of drugs to ambulatory patients. • Dispensing of controlled drugs.

2 2

Central Sterile Supply Unit and its Management • Types of materials for sterilization • Packing of materials prior to sterilization • Sterilization equipments • Supply of sterile materials

2 2


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4– Teaching and Learning Methods 4.1- Lectures 4.2- Tutorials 4.4- visiting to hospitals.

5- Student Assessment Methods



a First test 20%

b Second test 20%


6- List of References

6.1- Course Notes …………………………………………………….. 6.2- Essential Books (Text Books)

Textbook: • M. C. Allwood and J. T. Fell "Textbook of Hospital Pharmacy" Blackwell Scientific

Publications, Oxford 1980. Supplements:

• Remington's Pharmaceutical Sciences, A.R.Gennaro Ed. 18th ed. Mack Publishing Co. Pennsylvania, USA 1990.3.

• W.E. Hassan "Hospital Pharmacy" 3rd ed. Lea and Febiger, Philadelphia,1974.\ • Clinical Pharmacy - Jankins, Superandio and Laticlasis.

Course Coordinator:

Head of Department:

Date: / /

Manufacture of Sterile and Non-sterile Products • Policy making on manufacturable items • Demand and costing – • Master formula Card, • Production control, • Manufacturing records.

2 2

Total hours 14 14

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