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HONORS RESEARCH IN BMBTitle
Tolan ProfessorAPPLICATION AVAILABLE ON THE BMB WEBSITE OR IN THE BIOLOGY MAIN OFFICE
NotesArranged Lecture Times
Text(s)
Students must graduate with a minimum major GPA of 3.5 in order to receive honors credit; Participation in 2 semesters of the 1 credit Honors Semester (CAS BB 497/498); completion of CAS BB 401/402; completion and defense of senior thesis.
Grading
Prereq Senior standing, a 3.5 GPA in BMB with a 3.5 overall. Approval by the Research Honors Committee & Director of BMB.
Discussion/Lab Times
CAS BB 401/402Course #
Provides students with an opportunity to work closely with faculty who serve asintellectual and technical mentors in their exploration of biochemistry molecular biology and biomedical research. The potential for learning, scholarship and academic growth is a unique opportunity for BMB students to translate formal class work into research practice.
Summary
INTRODUCTORY BIOLOGY FOR THE ALLIED HEALTH SCIENCESTitle
CoProfessorNOT FOR BIOLOGY CONCENTRATION CREDIT-PRIMARILY FOR STUDENTS OF HEALTH & REHAB SCIENCES (SARGENT). NotesA1 M,W,F 9:00-10:00Lecture Times
Text(s)
3 Midterm and 1 cumulative final exam (75%); Lab (25%) Grading
Prereq High school biology and chemistry.
Discussion/Lab Times C1
C2C3D1
TTTW
D2E1E2E3
W RRR
9:30-11:3012:00-2:003:00-5:0010:30-12:30
1:30-3:309:30-11:3012:30-2:303:00-5:00
LAB TIMES
CAS BI 105Course #
Principles of biology, emphasis on cellular structure, genetics, microbiology,development, biochemistry, metabolism and immunology. This course is appropriate for non-majors andstudents in thehealth and paramedical sciences ( Sargent College). Students may not receive credit for BI 105 if BI 108 has already been passed. Three hour lecture, two hour labs. Carries natural science divisional credit (with lab) in CAS. Not for biology major credit.
Summary
BIOLOGY ITitle
Spilios, WassermanProfessorNotes
A1 T,R 12:30-2:00 A2 M,W,F 3:00-4:00Lecture Times
Sadava et al. Life:The Science of Biology, 10th ed. Sinauer Publ.,2014 and Lab: Spilios & Godrick (2015)Principles of Biology I, Plymouth,MI : Hayden-McNeil Publishers.
Text(s)
4 exams (68%), Lab ( 32%) [includes quizzes and reports]Grading
Prereq None
Discussion/Lab Times B1
B2C1C2C3C4
MMTTTT
C5C6C7D1D2D3D4
TTTWWWW
4:00-7:004:30-7:308:30-11:309:00-12:009:30-12:3012:00-3:00
12:30-3:301:00-4:004:00-7:008:30-11:309:00-12:009:30-12:3012:00- 3:00
D5D6D7E1E2E3E4
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12:30-3:301:30-4:304:30-7:304:00-7:008:00-11:009:00-12:0010:00-1:00
LAB TIMES12:30- 3:301:30-4:304:00-7:008:30-11:309:00-12:009:30-12:3012:00-3:00
RRRRFFF
CAS BI 107Course #
An introduction to evolution, ecology,behavior. Fulfills biology concentration,premedical student requirements and natural science divisional requirement.
Summary
READINGS IN BIOLOGYTitle
StaffProfessorNOT FOR BIOLOGY CONCENTRATION CREDIT (2 CREDITS)NotesArrangedLecture Times
Text(s)
Grading
Prereq Consent of instructor and permission required. Application required.
Discussion/Lab Times
CAS BI 171/172Course #
Library research for students at the freshman level, on a well-defined topic in biological science, chosen in conjunction with a faculty sponsor. Individual conferences and discussion with a faculty member, and paper preparation.
May NOT be used as credit towards the biology major or specializations.
Summary
UNDERGRADUATE RESEARCH IN BIOLOGY ITitle
StaffProfessorCAS BB 191/192 FOR BMB MAJORS ONLY (2 CREDITS) NotesArrangedLecture Times
Text(s)
Grading
Prereq Consent of instructor and permission required. Application required.
Discussion/Lab Times
CAS BI 191/192 or CAS BB 191/192Course #
Research in biological science for students at the freshman level. Design and implementation of a research project in conjunction with a faculty member.
May NOT be used as credit towards the Biology major or specializations, or the BMB major.
Summary
CELL BIOLOGY (CM)Title
BeffertProfessorM 5-6:30 RESERVED FOR EXAMSNotesA1 T,R 9:30-11:00 A2 T,R 3:30-5:00 Lecture Times
Cooper and Hausman, The Cell, 6th Edition, Sinauer, 2013.Text(s)
Three exams (85%), Discussion (15%) Grading
Prereq BI 108 and CH 102
Discussion/Lab Times B2
B3B4B5C1
MMMMT
D1D2D3D4D5
WWWWW
3:00-4:003:00-4:002:00-3:002:00-3:004:00-5:00
12:00-1:002:00-3:003:00-4:002:00-3:003:00-4:00
D6D7E1E2E3
WWRRR
DISCUSSION12:00-1:0012:00-1:004:00-5:001:00-2:002:00-3:00
CAS BI 203Course #
Examines the basic structure, function, and regulation of cells. Topics include macromolecules, energy transformation, membranes, cell signaling, cell cycle, organelle structure and function, cellular differentiation, and information processing.
Summary
HUMAN PHYSIOLOGYTitle
Co, SeligaProfessorNOT FOR BIOLOGY CONCENTRATION CREDIT--PRIMARILY FOR STUDENTS OF HEALTH & REHAB. SCIENCES (SARGENT). NotesA1 M,W,F 1:00-2:00Lecture Times
Human Physiology by Sherwood; Lab Manual by Seliga, McCarthy and Selagamsetty.
Text(s)
Lecture 75% and lab 25%. 4 hourly exams (3 midterm 1 final); Lab quizzes and write ups, lab midterm and final exams.
Grading
Prereq BI 105, BI 106 (anatomy ) and general chemistry
Discussion/Lab Times B1
B2C1D1D2D3
MMTWWW
E1E2F1
RRF
2:00-5:006:00-9:002:00-5:009:00-12:002:00-5:006:00-9:00
9:00-12:002:00-5:009:00-12:00
LAB TIMES
CAS BI 211Course #
Introduction to principles of systemic human physiology. Some knowledge of anatomy, biology and chemistry assumed. Three hours lecture, three hours lab.
Summary
INTENSIVE CELL BIOLOGY (CM) Title
NayaProfessorNotes
T,R 9:30-11:00Lecture Times
Text(s)
Grading
Prereq CAS BI 108 and CH 102. Coreq: CH 203
Discussion/Lab Times B1
B2B3B4
MWWR
1:00-2:0012:00-1:005:00-6:005:00-6:00
DISCUSSION
CAS BI 213Course #
An advanced alternative to CAS BI 203, this course is intended for students with a strong interest in cell and molecular biology. It is recommended for majors in BMB and for students intending to enter the experimental approaches used in contemporary cell and molecular biology, including a focus on current research problems and reading original research papers. Topics include genome organization,gene expression, membranes, subcellular organelles, cell signaling, the cell cycle, programmed cell death, stem cells and cancer.
Summary
INTRODUCTION TO BEHAVIORAL BIOLOGY (EBE)Title
TranielloProfessorNotes
A1 T,R 12:30-2:00Lecture Times
N/AText(s)
Three in-class written quizzes, Research paper, Group project & Presentation Grading
Prereq CAS BI 107 or CAS AN 102 and sophomore standing or higher
Discussion/Lab Times B1 T,R 2:00-2:30
DISCUSSION
CAS BI 225Course #
Introduction to genetics, physiology, neurobiology, ecology and evolution of behavior. Topics include gene/environment interaction, hormones and behavior, nerve cells and behavior, communication, reproductive behavior, cooperation and altruism, sensory biology and brain evolution, evolutionary psychology and human behavioral ecology . Emphasis on integrative analysis.
Summary
BEHAVIORAL ENDOCRINOLOGY Title
BaumProfessorALSO TAUGHT AS CAS NE 230 NotesA1 T,R 2:00-3:30Lecture Times
R.J. Nelson. Introduction to Behavioral Endocrinology, 4th ed. Sinauer, 2011.Text(s)
Midterm (20%), 2 class quizzes (20%), discussion participation (20%) and finalexam (40%)
Grading
Prereq CAS BI 108 OR BI 118 OR NE 102 and sophomore standing
Discussion/Lab Times R 3:30-5:00
DISCUSSION
CAS BI 230Course #
Hormonal control of reproductive behavior and social affliction, aggression, fluid homeostasis and feeding, biological rhythms, stress, psychiatric illness and steroid abuse.
Summary
READINGS IN BIOLOGYTitle
StaffProfessorNOT FOR BIOLOGY CONCENTRATION CREDIT ( 2 CREDITS)NotesArrangedLecture Times
Text(s)
Grading
Prereq Consent of instructor and permission required. Application required.
Discussion/Lab Times
CAS BI 271/272Course #
Library research, for students on the sophomore level, on a well-definded topic in biological science, chosen in conjunction with a faculty sponsor. Individual conferences and discussion with a faculty member, and paper preparation.
May NOT be used as credit towards the Biology major or specializations.
Summary
UNDERGRADUATE RESEARCH IITitle
Biology & BMB Faculty ProfessorCAS BB 291/292 FOR BMB MAJORS ONLY (2 CREDITS)NotesArrangedLecture Times
Text(s)
Grading
Prereq Consent of Instructor and permission required. Application required.
Discussion/Lab Times
CAS BI 291/292 or CAS BB 291/292Course #
Research in biological science for students at the sophomore level. Design and implementation of a research project in conjunction with a faculty member.
May NOT be used as credit towards the Biology major or specializations, or the BMB major.
Summary
BIOLOGY OF GLOBAL CHANGE (EBE) Title
TemplerProfessorNotes
A1 T,R 11:00-12:30Lecture Times
Richard Wright, Environmental Science Toward a Sustainable Future, 10th Ed.Pearsen, Prentice Hall.
Text(s)
Two exams (20%), final exam (30%), lab and participation (30%) Grading
Prereq CAS BI 107 and recommended CAS CH 101 or CH 171
Discussion/Lab Times B1
C1C2F1
TWWR
2:00-5:0010:00-1:002:00-5:002:00-5:00
LAB TIMES
CAS BI 306Course #
Covers the ecological impacts of human activity on terrestrial and aquatic ecosystems. Climate change, forest decline, eurotrophication, acidification, loss of species diversity and restoration of ecosystems.
Summary
EVOLUTION (EBE)Title
MullenProfessorNotes
A1 M,W,F 10:00-11:00 Lecture Times
Freeman & Herron, Evolutionary Analysis, 4th ed.Text(s)
Mid-term and final exams, discussion participation, plus one short writing assignment and a term paper.
Grading
Prereq BI 107, junior or senior standing, biology concentration.
Discussion/Lab Times
B1B2B3B4
RWWR
B5B6
WF
3:00-4:0012:00-1:001:00-2:002:00-3:00
4:00-5:001:00-2:00
DISCUSSION
CAS BI 309Course #
Modern concepts, controversies, and analytical approaches in evolutionary biology. Topics include: adaptation, natural and sexual selection, species and species formation, phylogenetics, origin of evolutionary novelty, adaptive radiation, basic population and quantitative genetics, development and evolution. Discussion will cover material from the recent primary literature and address major issues in evolutionary biology.
Summary
GENERAL MICROBIOLOGYTitle
TalbotProfessorNotes
A1 M,W,F 9:00-10:00Lecture Times
Text(s)
Grading
Prereq BI 203; BI 206 recommended
Discussion/Lab Times
B1B2B3B4
M,WM,WT,RT,R
12:00-2:003:00-5:009:00-11:002:00-4:00
LAB TIMES
CAS BI 311Course #
Organisms discussed include bacteria, arhaea, viruses, fungi, protists and algae. Course will cover mircobial diversity. The environmental and human microbiomes and technologies used to study microbes today. Global issues of emerging infectious disease, agriculture and microbial responses to global change are discussed.
Summary
SYSTEMS PHYSIOLOGY (PN)Title
Widmaier, Seliga (lab)ProfessorPREFERENCE GIVEN TO CAS BIO & SARGENT MAJORS IN THE SPRINGBIOMEDICAL ENGINEERING MAJORS IN THE FALL NotesA1 T,R 12:30 - 2:00Lecture Times
1) Vander’s. Human Physiology: The Mechanisms of Body Function. 13th edition2)Lab manual by Rycroft, et al.
Text(s)
Two hourly exams, final exam, lab quizzes and write ups, cummulative lab final. Grading
Prereq BI 108 or equivalent, and Introductory Chemistry
Discussion/Lab Times
B1B2C1C2
MMTT
D1D2D3
WWW
2:00-5:006:00-9:009:00-12:006:00-9:00
9:00-12:002:00-5:006:00-9:00
E1E2E3F1
RRRF
LAB TIMES
9:00-12:002:00-5:006:00-9:009:00-12:00
CAS BI 315 Course #
Examines the structure and function of the body’s major organ systems (nervous, endocrine, circulatory, respiratory, digestive and urinary) at the cell, tissue and organ levels. Special emphasis on regulatory and integrative aspects of feedback systems underlying the maintenance of optimal internal state required for survival in adynamic environment.
Summary
PRINCIPLES OF NEUROSCIENCE (PN)Title
Cruz-Martin, GavornikProfessorALSO OFFERED AS CAS NE 203 (WITH LAB) NotesA1 M,W,F 12:00-1:00Lecture Times
Bear, et al. Neuroscience: Exploring the Brain. 4th Ed. Wolters Kluwer.Text(s)
Two midterms and a final exam. Grading
Prereq BI 203 or consent of instructor. BI 315 recommended.
Discussion/Lab Times
B1B2
WW
FFFF
B1B2B3B4
2:00-3:003:00-4:00
9:00-10:0011:00-12:001:00-2:002:00-3:00
DISCUSSION NE DISCUSSIONS
CAS BI 325Course #
Fundamentals of structure and function of the nervous system. Topics include cell signaling and communication, sensory and motor systems, neural basis of learning and memory, and brain control of sleep states.
Students can register for any BI/NE discussion section.
Summary
READINGS IN BIOLOGYTitle
StaffProfessorNOT FOR BIOLOGY CONCENTRATION CREDIT ( 2 CREDITS)NotesArrangedLecture Times
Text(s)
Grading
Prereq Consent of instructor and permission required. Application required.
Discussion/Lab Times
CAS BI 371/372Course #
Library research, for students on the junior level, on a well-defined topic in biological science, chosen in conjunction with a faculty sponsor. Individual conferences and discussion with a faculty member, and paper preparation.
May NOT be used as credit towards the Biology major or specializations.
Summary
UNDERGRADUATE RESEARCH IN BIOLOGY IIITitle
StaffProfessorCAS BB 391/392 FOR BMB MAJORS ONLY (2 OR 4 CREDITS)NotesArrangedLecture Times
Text(s)
Grading
Prereq Consent of instructor and permission required. Application required.
Discussion/Lab Times
CAS BI 391/392 OR CAS BB 391/392Course #
Research in biological science for students at the junior level. Design and implementation of a research project in conjunction with a faculty member. Students must choose 4 credits to recieve credit towards their major.
Note Biology Majors: Up to 8 credits of research may be used toward Biology major and specializations. 4 credits may also be used toward the three-lab requirement. Note BMB Majors : Only 4 credits of research may be applied to the BMB major.
Summary
HONORS RESEARCH IN BIOLOGY Title
StaffProfessorNotes
Lecture Times
Text(s)
Student must graduate with a minimum major GPA of 3.5 in order to receive honors credit; One semester of the 2-credit research seminar (CAS BI 497/498); Two semesters of mentored research (CAS BI 401/402); Completion and defense of written senior thesis.
Grading
Prereq Senior standing, a 3.5 GPA in Biology with a 3.0 overall. Application required.Approval by the Research & Honors Committee.
Discussion/Lab Times
CAS BI 401 Course #
Provides students with an opportunity to work closely with faculty who serve asintellectual and technical mentors in their exploration of biological research. Honors students also participate in a 2-credit research seminar, providing exposure to a broad range of current science in the Biology research community.
Summary
ANIMAL BEHAVIOR (EBE)Title
WassermanProfessorNotes
A1 T,R 3:30-5:00Lecture Times
Alcock, Animal Behavior, 5th ed.Text(s)
Two lecture exams, a comprehensive final, lab write-ups, plus individual projects and write-ups. Graduate students will have an additional paper and lab.
Grading
Prereq BI 107
Discussion/Lab Times
B1D1F1
MWF
2:00-5:0012:00-3:002:00-5:00
LAB TIMES
CAS BI 407 Course #
The science of ethology on a hormonal, neural and evolutionary level. Special emphasis will be on significance and adaptiveness of an expressed behavior. Individual lab projects as well as some prepared labs may requiremore than the scheduled time.
Summary
BIOCHEMISTRY I Title
Perlstein & TolanProfessorCO-TAUGHT WITH CH 421/621; M 5:00-7:00: RESERVED FOR EXAMS NotesA1 M,W,F 9:00-10:00, M 8:00-9:00 | A2 T,R 2:00-3:30 Lecture Times
Voet,Voet, Pratt, Fundamentals of Biochemistry, 4th edition. Tolan, Biochemistry Laboratory Manual, 3rd edition.
Text(s)
Lecture 65%, lab 35%; mid-term exams, comprehensive final, lab reports. Graduate students will have extra assignments and discussion sections.
Grading
Prereq C or better in CAS CH 204,212,214.
Discussion/Lab Times BA
BBBCB1B2B3
MMFTWW
B4B5B6B7B8B9
WRRRFF
11:00-3:004:00-8:006:00-10:004:00-8:008:00-12:001:00-5:00
6:00-10:008:00-12:001:00-5:006:00-10:008:00-12:001:00-5:00
C1C2C3C4
MMTT
LAB TIMES DISCUSSION10:00-11:003:00-4:008:00-9:001:00-2:00
CAS BI 421Course #
Introductory biochemistry. Topics include amino acids, pH, protein structure with particular emphasis on protein folding, enzyme mechanisms, kinetics, and allostery; nucleic acid structure with particular reference to interactions with proteins and other molecules; carbohydrates, lipid and membrane structure with special emphasis on membrane proteins and transport; bioenergetics; vitamins and coenzymes; and introduction to intermediary metabolism. For lab exercises see BI 527 summary.
Summary
TERRESTRIAL BIOGEOCHEMISTRY Title
Finzi ProfessorINDEPENDENT. ALSO OFFERED AS CAS ES 443 NotesA1 M,W,F 11:00-12:00Lecture Times
Text(s)
Grading
Prereq CAS BI 107 or CAS ES 101 or CAS ES 105 & CH 101/102 or consent of instructor.
Discussion/Lab Times
CAS BI 443 Course #
The patterns and processes controlling element cycles in terrestrial ecosystems. Emphasis on climate change, links between the land surface and atmosphere at local to global scales.
Summary
DEVELOPMENTAL NEUROBIOLOGY Title
ManProfessorNotes
F 10:00-12:00 Lecture Times
Text(s)
One midterm exam, one final exams, and paper presentation.Grading
Prereq CAS BI 203 or CAS BI 325 or CAS NE 203 or consent of the instructor.
Discussion/Lab Times M 10:00-12:00
DISCUSSION
CAS BI 455Course #
The course covers the fundamental principles of developmental neurobiology. Emphasis will be placed on the cellular and molecular mechanisms underlying events including neuronal determination, neurogenesis, patterning, axonal growth and guidance, polarity, synaptogenesis, synaptic modification, and cell death.
Summary
READINGS IN BIOLOGYTitle
StaffProfessorNOT FOR BIOLOGY CONCENTRATION CREDIT ( 2 CREDITS)NotesArrangedLecture Times
Text(s)
Grading
Prereq Consent of instructor and permission required. Application required.
Discussion/Lab Times
CAS BI 471/472Course #
Library research, for students at the senior level, on a well-defined topic in biological science, chosen in conjunction with a faculty sponsor. Individual conferences and discussion with a faculty member, and paper preparation.
May NOT be used as credit towards the Biology major or specializations.
Summary
MOLECULAR BIOLOGY OF THE NEURON Title
HoProfessorALSO OFFERED AS NE 481NotesA1 M,W,F 1:00-2:00Lecture Times
TBAText(s)
Grading
Prereq CAS BI 203, BI 325
Discussion/Lab Times
B1 M 3:00-4:00
DISCUSSION
CAS BI 481 ᤫCourse #
The study of cellular and molecular neurobiology. Topics to be covered include: electrical properties of neurons, a survey of neurotransmitters, molecular structure of receptors, synaptic transmission, intracellular signaling, and the molecular biology of sensory transduction.
Summary
UNDERGRADUATE RESEARCH IN BIOLOGY IVTitle
StaffProfessorCAS BB 491/492 FOR BMB MAJORS ONLY (4 CREDITS)NotesArrangedLecture Times
Text(s)
Grading
Prereq Consent of instructor and permission required. Application required.
Discussion/Lab Times
CAS BI 491/492 or CAS BB 491/492Course #
Research in biological science for students at the senior level. Design and implementationof a research project in conjunction with a faculty member. Note Biology Majors: Up to 8 credits of research maycount as electives for the Biology major and specializations. 4 credits may also be used toward thethree-lab requirement. Note BMB Majors: Only 4 credits of research may be applied to the BMB major.
Summary
HONORS IN BIOLOGY SEMINARTitle
ProfessorNotes
ArrangedLecture Times
Text(s)
Regular attendance at seminars (50%) and the review paper (50%). The student’s research advisor assigns the course grade. A minimum grade of B+ is required to graduate with Honors in Biology.
Grading
Prereq CAS BI 107, CAS BI 108 and at least two additional Biology courses. Seminar is for juniors or seniors currently enrolled in or intending to apply to the Honors in Biology Program. Juniors enrolling in BI 497 or 498 must have a current faculty research mentor.
Discussion/Lab Times
CAS BI 497Course #
2-credit research seminars, providing exposure to the broad range of current science in the Biology research community. All Honors in Biology students complete one semester of either BI 497 or BI 498. Students attend the weekly Biology Department Seminar. Alternative seminar series may be attended if approved by the research mentor. The objective of this course is to provide students an opportunity to become engaged in the Biology research community and learn about a broad range of current research. Specifically, this course will: 1) expose students to cutting-edge research in all areas of Biology through the department-wide seminar series; 2) through seminars, present students with current research in the student’s fieldof interest; 3) help students develop the ability to process and critically evaluate ideas and data in current biological research; and 4) strengthen students’ scientific writing skills through the writing project due at the end of the semester.
Summary
GENETICS LAB ᤫ
Title
CelenzaProfessorPERMISSION REQUIRED. PRIORITY FOR BMB, BA/MA AND BIOLOGY CMG STUDENTS Notes NoneLecture Times
Lab manual and primary literature.Text(s)
Lab notebook, lab reports and quizzes, attendance and participation. Grading
Prereq CAS BI 203 and BI 206, senior standing and consent of instructor.
Discussion/Lab Times A1 T,R 11:00-2:00
LAB
CAS BI 513Course #
Genetic techniques such as mutant selection and screening, complementation,mapping, recombinant DNA and chemical genetic screening are taught using the model systems. Escherichia coli, saccharomyces cerevisiae and Arabidopsis thaliana. Short term and long term projects in which student formulate and test hypotheses.
Summary
THEORETICAL EVOLUTIONARY ECOLOGYTitle
BustonProfessorNotes
A1 M,W,F 11:00-12:00Lecture Times
No required textText(s)
Grading
Prereq BI 225;BI 260; or BI 303; or BI 309, and 1 semester of calculus; or consent of instructor.
Discussion/Lab Times
T 3:00-6:00
LAB
CAS BI 519Course #
Objective of this course is to familiarize students with the theory ofpopulation and evolutionary ecology. Students will gain background to read theoretical population and evolutionary ecology literature do simple modeling, and spring board to more complex theory; hands on experience through homework and computer labs.
Summary
SENSORY PHYSIOLOGYTitle
DavisonProfessorALSO OFFERED AS NE 520NotesA1 T,R 11:00-12:30 W 4:00-5:00Lecture Times
Text(s)
Three hours lecture plus one hour discussion involving student-led presentations of primary research papers.
Grading
Prereq BI 315 or BI 325, or consent of Instructor. Core biology, chemistry and physics; behavior, neurobiology or physiology recommended.
Discussion/Lab Times
B1 W 4:00-5:00
DISCUSSION
CAS BI 520 Course #
A broad survey of how sensory information is detected and encoded in the brain, in both humans and the animal kingdom. Topics range from basic sensory transduction, cortical processing, neural coding, and the relationship between neural activity and sensory perception.
Summary
BIOLOGY OF NEURODEGENERATIVE DISEASESTitle
PastorinoProfessorINDEPENDENT. ALSO OFFERED AS NE 525 NotesA1 M,W,F 9:00-10:00 Lecture Times
Detailed handouts, powerpoint presentation, PDF files on course websiteText(s)
2 midterm exams 46%; final exams 24%; assignments 15%; paper presentation 15%Grading
Prereq (CAS BI 203 or CAS NE 102) and (CAS BI 325 or CAS NE 203 )
Discussion/Lab Times W 10:00-11:00
DISCUSSION
CAS BI 525 Course #
This course focuses on understanding the molecular mechanisms that are at the basis of neurodegenerative diseases and on their impact and relevance in clinical diagnosis and treatment. Neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease, Amyotrophic Lateral Sclerosis, Huntington Disease and Cruetzfeldt-Jacob disease are becoming more and more common since people are more exposed to pathogenic agents ( as in Cruetzfeldt-Jacob disease and Mad Cow disease) or just encounter these diseases as a result of aging ( like Alzheimer’s or Parkinson’s disease). Although very different from on another, these diseases share common mechanisms and features leading to neuronal death, including protein misfolding and aggregation, oxidative stress, impaired protein degradation, and apoptosis. This course will study how these molecular pathways define each disease, contributing to neurodegenerative phenomena. Relevance will be given to Alzheimer’s disease.
Summary
BIOCHEMISTRY LAB ITitle
Perlstein, TolanProfessorNotes
A1 M 10:00-11:00 | A2 M 3:00-4:00 | A3 T 8:00-9:00 | A4 T 1:00-2:00Lecture Times
Tolan, Biochemistry Lab Manual, 2nd edition Text(s)
Lab preparation, lab reports, final exam.Grading
Prereq CAS CH 204, CH 212 OR CH 214. Co req: GMS BI 751
Discussion/Lab Times BA
BBBCB1B2B3
MMFTWW
B4B5B6B7B8B9
WRRRFF
11:00-3:004:00-8:006:00-10:004:00-8:008:00-12:001:00-5:00
6:00-10:008:00-12:001:00-5:006:00-10:008:00-12:001:00-5:00
LAB TIMES
CAS BI 527Course #
A biochemistry lab for those interested in practical experience. Those BMB majors enrolled in GMS BI 751 should take this course as a corequisite. Suitable for biology majors and graduate students as a upper division lab. Exercises in buffer chemistry, spectroscopy, protein and DNA electrophoresis,isozyme analysis and restriction enzyme digestion. This is the lab portion of BI/CH 421/621.
Summary
TRANSITIONAL RESEARCH IN ALZHEIMER’S DISEASETitle
PastorinoProfessorINDEPENDENT. ALSO OFFERED AS CAS NE 535NotesA1 M,W,F 2:00-3:00 W 3:00-4:00Lecture Times
Detailed handouts provided by the instructorText(s)
2 midterm exams (46%) Final exam (24%) assignments (15%), paper presentation (15%)
Grading
Prereq (CAS NE 102 or CAS BI 203) and (NE 203 or BI 325)
Discussion/Lab Times
CAS BI 535Course #
An introduction of concepts in translational research in Alzheimer’s Disease. From observations of pathogenic phenotypes in the brain to the development of appropriate animal and cellular models, the course will discuss how biomedical research develops searching new therapeutic targets for the disease.
Summary
STEM CELLSTitle
FrydmanProfessorPERMISSION REQUIREDNotesA1 T,R 11:00-12:30Lecture Times
Reviews & reserach papers (will be provided), Essentials of Stems Cell Biology, ed: Lanza, Gearheart, Hogal, Melton, Pedersen, Thomson, Thomas, and West, Academic Press (Not Required).
Text(s)
1 midterm, 1 final exam and oral presentations from scientific papers. Midterm 30%; Final Exam 40%; Oral presentation and discussion 20%: Participation 10%.
Grading
Prereq BI 203/ 213 and BI 206/216
Discussion/Lab Times B1 R 12:30-1:30
DISCUSSION
CAS BI 551Course #
Stem cell research is a hot topic of debate in the non-scientific press. Some view this field as a potential panacea for most human diseases, while others view this research as opening a Pandora’s box that will trivialize human life. This course will take a closer look into the SCIENCE behind this discussion: during development, stem cells form issues and organs. In the adult, stem cells maintain and regenerate tissues after injury. In the first part of this course we will review basic concepts and cover contributions to stem cell research from model organisms. The second part will explore past and current experiments aiming towards the utilization of stem cells for regenerative medicine. Since most of the reading is from the scientific literature,this class is intended for upper level undergraduates and graduate students. Exceptions will be made for others with enough cell biology and genetics background.
Summary
MOLECULAR BIOLOGY I Title
LoechlerProfessorNotes
A1 T,R 3:30-5:00Lecture Times
Text(s)
Three exams, homework and class participation. Grading
Prereq BI 203/213 and BI 206/216
Discussion/Lab Times B1
B2B3B4
TWWR
5:00-6:0010:00-11:002:00-3:005:00-6:00
DISCUSSION
CAS BI 552Course #
Prokaryotic molecular biology(2/3); introduction to eukaryotic molecular biology (1/3). The synthesis and function of biologically important macromolecules ( DNA, RNA and proteins) Regulation and control of the synthesis of DNA, RNA, proteins. Introduction to molecular biological techniques including genetic and recombinant DNA techniques.
Summary
SYSTEMS BIOLOGYTitle
SiggersProfessorNotes
A1 M,W,F 11:00-12:00Lecture Times
Scientific papers and chapters from books will be made available through the class website.
Text(s)
Midterm 1 (20%), Midterm 2 (30%) final exam (30 %) participation (20%)Grading
Prereq CAS BI 552 or consent from instructor.
Discussion/Lab Times W 12:00-1:00
DISCUSSION
CAS BI 560Course #
The course will examine two critical components to emerging discipline of systems biology1) large-scale data sets and biological networks 2) design principles in biological systems.We will cover emerging (and established) techniques and concepts in areas such as geneexpression analysis, proteomics, genomics, and microbiomics. We will examine design principles in biological systems such as feedback, cooperativity, signaling scaffolds and regulatory network motifs. The goal of this course is to provide exposure and an appreciation for the techniques and concepts of systems biology.
Summary
SEMINAR IN BIOLOGY : Exploring Neural Circuits Title
Cruz-MartinProfessorNotes
M 10:00-12:00Lecture Times
Based on readings from research articles.Text(s)
Based on participation during seminar, oral presentation of research articles and writing a final mini proposal on a topic of interest.
Grading
Prereq CAS BI 325 or consent of instructor.
Discussion/Lab Times
CAS BI 581 C1Course #
A major goal of neuroscience research is to understand how the coordinated patterns of neural activity lead to complex behavior. The brain accomplishes this feat by combining different cell types and wiring them to create neural circuits that havethe ability to process information in a variety of ways. Although, the inherent complexity of neural circuits has been difficult to explore, a recent flurry of parallel technological advancements promises to shed light into thecontribution of specific cell types a nd circuits in information processing and behavior. This course will use current research articles to review the new toolsets that are being developed to dissect neural circuits, such as optogenetic and pharmacogenetic approaches, in vivo ִmeasurement strategies with genetically encoded calcium indicators (GECIs), viral tracing approaches to label and to ֬manipulate neural activity and multiple mouse transgenic intersectional strategies. In addition, the course will rely heavily on discussion of recent literature that combines these approaches to dissect the function and wiring patterns of specific neural circuits.
Summary