fluid theraphy
9
Colloid Solution o Liquid which has a large molecule called colloids. The colloids can not easily pass through the membrane separator compartment because of the small size of the membrane pores. The force that urges the membrane caused by osmotic gradients generated by this coloid called colloidal osmotic pressure (COP). o Particles in the blood that causing COP are proteins- globulins , fibrinogen and albumin. Extravascular fluid will move into the interstitial space when the intravascular hydrostatic pressure increases above the COP, increased membrane pore size, or intravascular COP becomes lower than the COP interstitial. If this fills the interstitial volume loss, so the result is rehydration. Excess volume causes edema.
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Liquid which has a large molecule called colloids. The colloids can not easily pass through the membrane separator compartment because of the small size of the membrane pores. The force that urges the membrane caused by osmotic gradients generated by this coloid called colloidal osmotic pressure (COP).Particles in the blood that causing COP are proteins-globulins , fibrinogen and albumin. Extravascular fluid will move into the interstitial space when the intravascular hydrostatic pressure increases above the COP, increased membrane pore size, or intravascular COP becomes lower than the COP interstitial. If this fills the interstitial volume loss, so the result is rehydration. Excess volume causes edema.
Transcript of fluid theraphy
Colloid Solutiono Liquid which has a large molecule called colloids. The colloids can
not easily pass through the membrane separator compartment because of the small size of the membrane pores. The force that urges the membrane caused by osmotic gradients generated by this coloid called colloidal osmotic pressure (COP).
o Particles in the blood that causing COP are proteins-globulins , fibrinogen and albumin. Extravascular fluid will move into the interstitial space when the intravascular hydrostatic pressure increases above the COP, increased membrane pore size, or intravascular COP becomes lower than the COP interstitial. If this fills the interstitial volume loss, so the result is rehydration. Excess volume causes edema.
(1)fluid resuscitation in patients with severe intravascular fluid deficits (eg, hemorrhagic shock) prior to the arrival of blood for transfusion(2)fluid resuscitation in the presence of severe hypoalbuminemia or conditions associated with large protein losses such as burns. In burn patients colloids should also be considered if the injury involves more than 30% of the body surface area or if more than 3–4 L of crystalloid has been given over 18–24 h postinjury.
Factors To Be Considered
• The timing of fluid replacement• The type of fluid replacement• The volume• Criteria for guiding volume therapy , that is
the end points of resuscitation• Possible side effects• Cost
Comparison Crystaloid Electrolit
Comparison Coloid Electrolit
ICF ISF IVF
Dextrose 5%
RL, NaCl 0.9%
Colloid-Blood-Plasma-Plasma expander
Distribution of IV Fluids
Total ICF ISF IVF
Dextrose 5% 3 L 750 cc 250 cc 2 L
Crystaloid ( RA, RL, NaCl 0.9%/
3 L 2270 cc 750 cc
Albumin 1 L 1 L
Comparison
Perioperative Fluid Therapy• Perioperative fluid therapy includes replacement of
preexisting fluid deficits, of normal losses (maintenance requirements), and of surgical wound losses including blood loss.
• Normal maintenance requirement
• Preexisting deficits• The deficit can be estimated by multiplying
the normal maintenance rate by the length of the fast. For the average 70-kg person fasting for 8 h, this amounts to (40 + 20 + 50) mL/h x 8 h, or 880 mL.
