FITT Newsletter Jan 13

7/28/2019 FITT Newsletter Jan 13

1/16

i3 National Fair at IIT Delhi

International Conerence - Towards a Better InnovationEco-System, September 20-21, 2012, New Delhi

Wallonia Tech India Program (Belgium) November12,wherein FITT is partnering with AWEX; www.awex.in

Innovation | Technology | Business

Newsletter o Foundation or Innovation and Technology Transer,Indian Institute o Technology Delhi, New Delhi

FITT FORUMISSN-0972-2548

Vol. 19 No. 1, January 2013

Content

Invited Articles

Enzyme Engineering or EnhancedStability and Anti-leukemic Activity

02

Regenerative Engineering 04

New Approaches or Clustering Data 07

Faculty Proles

Pro. Vinod Chandra 09

Pro. V. D. Vankar 10

FITT / IIT Delhi Happenings 11

Innovations

Opportunities or IP Licensing 12

Technology Proles 12

R&D Projects 14Proessional Development Programmes 15

Miscellaneous 16

Year 2012 saw the music sensation PSYs Gangnam Style go viral and

create ripples (the music video has already been viewed over a billion

times!) - demonstrating the power and reach o internet media. The

power o mainstream TV and social internet media was also evident in a

dierent albeit, unortunate circumstances when people rom all walks

o lie in the country came out to express their anguish over a gory andhorrendous occurrence that o lethal violence (symptomatic o a larger

social malaise) against an innocent girl in Delhi. The country was jolted

by this sad event at the ag end o 2012. Wide ranging condemnation

and strong calls or justice quite shook the nation out o some lethargy.

The case may just serve as an inexion point in public awareness and

discourse, and hopeully catalyze afrmative action against atrocities

and criminality in our society. In this context, it was ironical to have an

editorial in New York Times (NYT), describing India as a country which

basks in its success as a growing business and technological mecca but

tolerates shocking abuse o women. This and numerous other views

speak eloquently about the incongruous issues amongst us - contributedin a large measure by a variety o actors that include social, governance

or legal deciencies and systemic ailures. Fortunately, when ordinary

looking yet intractable challenges conront us we do look towards

technology or some salvation. I we can work towards developing /

deploying technologies to detect malignant cells, prevent countereiting,

detect enemy positions, create deensive ware and to address several

other administrative challenges, we may as well, look towards developing

credible and eective new technology based deterrents to ensure saety

o people at large and the vulnerable amongst us, in particular! Let that

be one o the priority challenges or the innovators. We may have to

go beyond a ew Apps and the chili powder! Hopeully, the innovationand techno-entrepreneurial ecosystem shall not be ound wanting in

addressing its share o responsibility!

FITT at IIT Delhi contributes in a small measure to enable meaningul

partnerships to address technological challenges as we too are

stakeholders in the growth and development agenda o the country.

We have been at it or several years now. While our perormance during

the past year was steady, we hope to maintain the momentum in our

multiarious activities more particularly towards ostering innovations,

technology commercialization and start-up businesses. We hope

the period rom 2013 onwards heralds a new wave o high impactinnovations.

Best!

Anil Wali

Technology Salvation


2/16

2 | January 2013

Invited Articles

Enzyme Engineering or Enhanced Stability and Anti-leukemic Activity

Enzymes constitute one o the most crucial elements in

biological systems. In view o their robustness, enzymes have

been exploited in numerous areas that include medicine,

research, ood and dairy industry, paper industry, biouelindustry, etc. They have been widely used as therapeutics

or treatment o several clinical conditions like cancers,

anemia, cold, diarrhea, colitis, ood allergies, etc. Their clinical

application is however limited by one major drawback which

is their lack o stability. Most enzymes have a very limited

hal lie inside the human body and get degraded with time,

necessitating their continued and prolonged application or a

consistent eect. Such continued use may not only add to the

cost o treatment but may also be accompanied by negative

side eects on the body. It is thereore crucial to enhance their

stability to develop an eective clinical treatment.

Owing to their ubiquitous presence in nature, enzymes have

evolved to unction under widely varying environmental

conditions. Despite the environmentally sensitive proteomic

nature o most enzymes, many have been ound to be optimally

active at temperatures as high as 90C to sub zero temperatures.

These have been appropriately classied as thermophilic,

mesophilic and psychrophilic enzymes. Thermophilic enzymes

are well characterized or their stability and activity at high

temperatures. These enzymes have been ound to be potent

in extremes o hot springs bringing about speedy, error reecatalysis. By virtue o their stability, these could thereore serve

as attractive targets or clinical application by manipulating

them to work optimally at physiological temperatures.

Enzyme therapy or leukemia

Leukemia is a collection o diseases used to describe cancers

o the blood and bone marrow. Wide varieties o treatments

are currently in place to tackle the disease, with one o them

being the administration o the enzyme asparaginase. The

basis o this enzymatic therapy ollows rom the act that

cancer cells are deective in their ability to produce asparaginerequired or their survival and depend on blood or its supply.

So application o asparaginase, that hydrolyzes asparagine in

Dr. Bishwajit Kundu

Associate Proessor

Kusuma School o Biological Sciences,

Indian Institute o Technology, Delhi

the blood, is an eective treatment since it starves the cancer

cells o asparagine (Figure 1).

Figure 1: Antileukemic activity o Asparaginases; A - Normal cells cansynthesize asparagine rom aspartate. B - Cancer cells with very lowasparagine synthesis capability, depends on blood asparaginase or survival.C - Asparaginase degrades the blood asparagine, rendering the cancer cellsto die o asparagine starvation

Figure 2: Drawbacks (A) and side efects (B) o treatment with less stablecommercial asparaginases

Most o asparaginase based therapies utilize the mesophilic

orm o the enzyme, which works optimally at physiologicaltemperatures. Although efcient, the enzyme has several

drawbacks like low stability inside the body, an associated

undesirable glutaminase activity and immuno-reactivity

(Figure 2). Owing to its low stability the therapy requires

multiple dose administration that urther exacerbates its side

eects on the body in addition to increasing the cost.

We thereore, proposed a novel protein engineering strategyso as to counter this problem. Asparaginase rom the organism

Pyrococcusuriosus is highly thermostable and displays efcient


3/16

January 2013 | 3

Figure 3: Modulation o PA active site or higher activity

catalytic activity albeit at high temperatures. Most o the

protein engineering strategies till now have ocused on

engineering a mesophilic enzyme to enhance its stability.

Taking the reverse approach, we propounded the engineering

o a thermophilic enzyme to increase its mesoactivity,

thereby, producing a catalyst that is stable and active at body

temperatures.

We thereore, developed three dierent mutants o the wild

type, PyrococcusuriosusAsparaginase (PA) that had mutations

in the active site amino acid residues o the enzyme. These

residues were selected by comparing the structures o PA and

EcAII (E. coliasparaginase type II) and choosing the residues

which accounted or the dierence in active site topology o

the enzymes and resulting in an open conguration or easysubstrate accessibility (Figure 3). Accordingly, two amino

acids were identied as targets or mutation and were used to

construct single as well as double mutants.

These mutants showed remarkable results when testedor dierent aspects o therapeutic use. Firstly, one o the

mutants showed considerably high catalytic efciency

over the wild type and the other mutants at physiological

temperature. Secondly, all o the mutants were devoid o any

glutaminase activity, a highly desirable therapeutic property.

Further, the same mutant showed signicant resistance to

trypsin digestion, suggesting increased stability o the enzyme

inside the body since one o the reasons or ineectiveness

o mesophilicasparaginases is their proteolytic digestion and

early removal rom the system. Finally, these mutants were

tested or their cytotoxic (cellular killing) eect against leukemicand non leukemic cell lines. All o them exhibited extremely

potent cytotoxicity at very low concentrations as compared to

We Value Your Feedback

FITT seeks to explore various avenues to enhance thequantum o interaction between industrial units / end-

users and IIT Delhi. Thereore, we keenly look orward to

your eedback and suggestions on various issues that can

help to meet our objectives.

Write: [email protected]

those employed or presently used mesophilicasparaginases.

Also, these mutants were highly specic in action, targeting

only leukemic cells and displaying insignicant reactivity

towards non leukemic cell lines.

These results demonstrate that by mutating the thermophilic

enzyme PA at one criticial active site residue, we can produce

a protein that is stable, specic, potent and devoid o any

unwanted side eects. In light o these attributes, this enzyme

can serve as a avorable replacement or the currently used

asparaginase to overcome the pitalls o the existing therapy.

Not only did this approach help us in engineering a new

enzyme, it also brought to light some very interesting

mechanistic insights about asparaginase activity. Asparaginaseenzymes generally have two active sites consisting o two

dierent catalytic triads, i.e., three dierent amino acids at each

active site. Close inspection o the PA structure revealed that a

critical tyrosine residue might be unctioning in both the triads

by ipping between both the active sites. This is dierent rom

known triads o other asparaginases that contain separate

amino acid residues or the two triads.

Thus, protein engineering as a eld empowers us with the

ability to manipulate and play with protein structures. This

not only helps us with construction o novel, useul moleculesbut also enhances our knowledge o the existing structures.

It is only when we completely understand the biology o the

available plethora o proteins that we can envision and embark

upon the molding o dierent structures to yield innovative

models. Proteins regulate and orchestrate the biology o

lie and it is thereore o utmost signicance to explore

these mystic structures to deepen our understanding o the

unctioning o lie.


4/16

4 | January 2013

Regenerative Engineering

Concept o using textiles in simulating human body parts is

not a novel idea. In 1543 amous European physician and

anatomist Andreas Vesalius (15141564) wrote a textbook

o human anatomy, named De humani corporis abrica libri

septem (On the abric o the human body), where he depicted

that most o the organs are made up o brous tissues. In our

laboratory, we are trying to develop various architectures maderom brous textile materials, to simulate shape, anatomical

orientation and mechanics o human tissues.

During the last decade, Tissue Engineering research has

made ascinating progress towards the abrication o tissue

constructs in laboratory to repair or replace lost morphology

and unctions in diseased or damaged organs, in an attempt

to meet the demand o our increasingly aged society. As

sant Kabir, who was also a weaver, mentioned lie as a jhini

bini chadariya (kahe ke tana kahe ke bharni, kauntaar se bini

chadariya), we also wonder which polymeric bres can be bestsuited to prepare abric (scaold) to engineer specic tissues.

Proper selection o scaold composition and architecture will

allow cells to multiply to ll the scaold and deposit new extra

cellular matrix (ECM) to resemble native tissue.

The ideal scaold should be biocompatible, biodegradable,

porous, permeable. We use various biopolymers (alginate,

chitosan, gelatin) or synthetic polymers or developing

scaolds, but Silk is our most avourite choice. Silk bre can

meet the growing need or highly specialized biomaterials

due to their biocompatibility, stability and mechanicalproperties, ease o chemical modication, controlled

degradability, nominal immunological response. The Silk

Fibroin protein consists o a light chain (molwt~26 kDa)

and a heavy chain (molwt~390 kDa) linked by a disulde

bond. Silk broin is a block copolymer rich in hydrophobic

beta-sheet-containing blocks, linked by small hydrophilic

moieties. The crystalline regions are primarily composed o

Glycine-X repeats, where X could be alanine, serine, threonine

or valine. Subdomains enriched in glycine, alanine, serine and

tyrosine are placed within these domains. This arrangement

results in a hydrophobic protein that sel-assembles to ormstrong and resilient materials. This understanding enables

us to develop large variety o three dimensional (3D)

architectures o biomaterials, in the orm o bres, hydrogel,

denatured porous geometry, bre-hydrogel composites,

textile structures (weaving, braiding, knitting, nonwoven) or

patterned lm. Electrospinning technique allows development

o matrixes simulating nano-brous architecture o ECM o

human tissues. Scaolds can also serve as a vehicle or cell

delivery and growth actor delivery, to guide the orderly

development and dierentiation o the neo-tissue. For

controlled and targeted delivery o bioactive molecules

pH-responsible polymers could be a ascinating choice (Re 1).

Development o 3D tissue models or in vitro assays

For design o therapeutic options or human diseases it ismandatory to test candidate pharmaceutical compounds

beore applying in the clinic. Biologists culture cells on at

petri dishes to check efcacy o drugs. But in most cases,

investigational drug molecules perorming successully in

monolayer culture o diseased cells ail to respond in later

stages during animal or human trial. Transgenic or genetically

engineered animal models play crucial role or development

o clinical protocols. But due to their specic physiology

and dierences in genomics, they cannot exactly predict

the reaction o the human patients metabolism, telomere

regulation mechanism. Animal-based experiments are costly.Ater European Unions ban o using animal models or trials o

cosmetic products pharmaceutical companies are desperately

looking or better drug screening assays, preerably using

human cell-based diseased models which would allow

appropriate transerability o the results.

Figure 1: Methods o preparing 3D tissues

Dr. Sourabh Ghosh

Assistant Proessor

Department o Textile Technology,



5/16

January 2013 | 5

Figure 2: Subtle diference in compliance o nano-brous matrix can guidestem cells to migrate and orm aggregate

Figure 3:Tissue engineering o intervertebral disc (a. Goat IVD, b.Orientation o cells and ECM bres in human Annulus tissue, c. Orientationo silk bres and cells on scafold, d. Tissue engineered disc)

Accumulating evidences suggest that 3D cell culture models

are undamentally superior to monolayer systems with

respect to mimicking physiologically relevant conditions.

Aggregation o cells in 3D clusters can be achieved by using

various strategies e.g., culturing on non-adherent surace,

using bioreactors, or upon various commercially available

matrixes (Figure 1). We acilitate cell aggregation by culturing

them over Poly-Hydroxy ethyl methacrylate coated dishes,

or by growing cells in 3D textile scaold matrixes (Figure 1).

Based on knowledge o human genome, understanding o

cell biology and insight into engineering aspects required to

maintain 3D tissue systems we are trying to establish disease

model systems or cancer or Osteoarthritis. Nonionic tethering

o pro-inammatory cytokines on chemically modied silk

could modulate transcription prole o healthy humanchondrocytes, which dramatically replicated gene expression

prole o osteoarthritic cartilage tissue rom patients.

We have reported that bone marrow derived stem cells and

embryonic stem cells can sense subtle dierence in stiness o

underlying nanobrous matrixes, and start to sel-aggregate toprepare tissues (Figure 2). This interesting nding could lead

to establishment o in vitro model to simulate mesenchymal

condensation mechanism o developmental biology (Re 2).

Tissue engineering

Using Tissue engineering strategies we are trying to engineer

cartilage, bone, intervertebral disc, cornea, muscle in the

context o their specic 3D anatomical architecture and

unction. Intervertebral disc (IVD) makes the spine exible to

bend and twist in all directions. Ageing process or injury to

IVD lead to dehydration o inner gel, cracks in Annulus tissue,disorientation o collagen bres, resulting in protrusion o

hard Nucleus Pulposus and application o pressure on spinal

nerve, causing chronic back pain (slipped disc). The current

approach or treating such degenerative disc problem is

through reduction o inammation and physiotherapy. Upon

urther degeneration, disc is surgically removed and ceramic or

metallic discs are implanted, at the cost o reduced exibility

o the spine. Replacement o degenerated disc by a tissue

engineered substitute could oer major advantages over

arthroplasty or implantation o prosthetic disc, in terms o

possibility o initial matching o biomechanical properties and

adaptive remodeling in the long term.

Several research groups around the world are attempting to

develop bioengineered IVD. But none o these studies could

successully simulate the precise anatomical orientation o

collagen bres in Annulus tissue in criss-cross lamellar ashion.

As a result, mechanical properties o most o these engineered

tissues are several orders o magnitude below the stiness oIVD. We have developed a silk scaold having custom-made

ber alignment, where silk bres are aligned at 30-40 degree

to the scaold axis, and in alternate direction in successive

layers. This brous alignment allowed cells to deposit brous

ECM proteins at a desired orientation (Figure 3) and ultimately

developed optimum biomechanical unctions o the IVD

tissue. Furthermore, silk bres were chemically modied to

attach chondritin sulate, an important component o cartilage

tissue, to prepare enhanced chondrogenic microenvironment.

Taken together, combined eect o chemical composition and

microstructural organization o scaold gives rise to anisotropicand nonlinear mechanical behaviors replicating biomehanics

o disc tissue.

A

D

B

C


6/16

6 | January 2013

Rotator cu muscle tear is common problem in players as well

as aged people, leading to debilitating pain, reduced shoulder

unction. We have developed braided silk tapes replicating

elastic behaviour o human rotator cu muscle (Figure 4).

Structural integrity, durability, design exibility and precisiono braided textile structures make them highly potential or

such challenging application.

Personalized approach

Tissue engineering studies are moving in the direction

towards personalized therapeutic strategies, where scaolds

need to be abricated in tissue-specic, patient-specic

architecture. Direct-write technique, a miniaturized Rapid

Prototyping, is one o the promising approaches to develop

microperiodic complex architectured scaolds. Clinical

images captured rom the area o deect in patients body canbe converted to virtual 3D architectures using CAD sotware.

Using that image the computer-controlled translation stage

o direct-write system can move a syringe barrel incorporated

with ink deposition micro-nozzle in a layer-by-layer ashion,

to orm controlled and complex 3D construct. But proper

selection o polymeric ink composition and tailor made

viscoelastic properties are main challenges to ensure smooth

deposition o ink and shape retention (Re 4).

Obstacles remain

International community o tissue engineers is trying todesign new generations o biomaterials with exciting new

unctionalities. Problems related to availability o unding,

precise optimization o strategies to make scaolds o

specic chemistry, stiness, architecture or directing cell

behaviour, limited understanding o human physiology,

ethical issues, controlled clinical trials are enthralling them.

Material scientist, cell biologists, biotechnologists and

clinicians are trying to learn rom each other and to contribute

to each other. Considerable progress has already been

achieved resulting rom interdisciplinary interaction among

researchers o various elds. For example Pro. Farshid Guilak

(Proessor o Orthopedic surgery rom Duke University) and

Pro. Lisa Freed (a biologist rom MIT) realized potential o textile

technology and hired a mechanical engineering undergrad

student to abricate a 3D weaving loom, and developed

cartilage tissue constructs (Re 5). Such dynamic approach is

still unthinkable in India, because multidisciplinary approacho problem solving is still not understood and appreciated by

administrative authorities, biotechnology industries and even

by the researchers. There is a saying that, it is difcult to insert

new ideas in brain, but it is more difcult to take old ideas out.

Hopeully pieces will all into place, and Tissue engineering

research in India will ourish in near uture.

Reerences

Unveiling the sel-assembly o Poly (AAc-co-DMAPMA) in1.

situ to orm smart monolith displaying nanogels-within-

macrogel hierarchial morphology, A Das, S Ghosh, A R Ray,Polymer, 52, 2011, 3800-3810.

In vitro model o mesenchymal condensation during2.

chondrogenic development, S Ghosh, M Laha, S Mandal,

S Sengupta, D Kaplan, Biomaterials, 30, 2009, 6530-6540.

Oriented lamellar silk brous scaolds to drive cartilage3.

matrix orientation: towards Annulus Fibrosus tissue

engineering, M Bhattacharjee, S Miot, A Gorecka, K Singha,

M Loparic, S Dickinson, A Das, N S Bhabesh, A R Ray, I Martin,

S Ghosh, Acta Biomaterialia, 8, 2012, 3313-3325.

Direct-Write Assembly o Micro-Periodic Silk Fibroin4.

Scaolds or Tissue Engineering Applications, S Ghosh,

S T Parker, X Wang, D L Kaplan, J A Lewis, Advanced

Functional Materials, 18, 2008, 1883-1889.

A biomimetic three-dimensional woven composite scaold5.

or unctional tissue engineering o cartilage, F Moutos,

L Freed, F Guilak, Nature Materials, 6, 2007, 162-167.

Figure 4: a. Myobres o goat muscle, b. Comparison o mechanicalproperty o muscle and textile braids, c. Myoblasts growing on silk scafoldand using together, d. Architecture o textile braid

A B

D C


7/16

January 2013 | 7

New Approaches or Clustering Data

Clustering data is one o the central problems in Machine

Learning and Data Mining. Here, we will talk about new

approaches or clustering data that are being developed at

CSE, IIT Delhi.

Introduction

Clustering, in general, is the problem o grouping objectsinto separate classes such that similar objects are in the same

class. For instance, given some news articles, we might want to

group these articles into various classes like sports articles,

political articles etc. Another example is clustering medical

data into classes that represent diseases. Clustering is usually

the rst step in understanding large datasets that may be

generated in scientic and social experiments.

To be able to tell how well a clustering algorithm perorms,

we need a measure o similarity or dierence between pairs

o objects. In most practical cases, objects are represented aspoints in some ddimensional Euclidean space and the popular

dierence measure in this setting is the squared Euclidean

distance. The k-means problem is one o the most used and

well-studied problems in this setting. The ormal denition o

this problem is: given n points in a d-dimensional Euclidean

space, nd kpoints (called centers) such that the sum o square

o the distance o every point to its closest center is minimized.

Note that these kcenters give an implicit clustering o the data

points, all points closest to a single center being in the same

cluster (see Figure 1(d)). Mathematically, the problem can be

written as:

Given P = {p1,,p

n} Rd, fnd C = {c

1,...,c

k} Rdsuch that

(P,C)=pP

mincC

D(p,c) is minimized. Here D(p,c) denotes

squared Euclidean distance between points p and c.

algorithm perorms very badly. One o the main reasons or

poor perormance o the Lloyds algorithm is poor choice o

the initial k centers. To be able to x this problem, one needs

to come up with a ast and simple algorithm that picks the

initial kcenters in a cleverer manner. It turns out that a simple

sampling based algorithm helps to quickly nd k centers.

Moreover, this sampling algorithm solves the k-means

problem and there is a perormance guarantee attached with

it. This sampling algorithm is popularly called the k-means++

algorithm [Arthur and Vassilvitskii, 2007] and all it does is

randomly sample kpoints in the ollowing manner:

This problem is believed to be a hard problem to solve

efciently. The most popular heuristic algorithm that is used

to solve this problem in practice is the Lloyds algorithm. The

algorithm starts with k centers chosen arbitrarily, and in a

sequence o steps, shits these centers while improving the

solution each time. Even though this algorithm perormswell in practice, it does not have perormance guarantees.

This means that there are certain datasets or which this

Figure 1:The gure shows a two dimensional dataset being clustered intoour clusters using the sampling algorithm. The algorithm samples thecenters in our simple steps. The rst center is chosen randomly. For thesecond center, the points that are urther away rom the rst center aregiven more priority and so on

The above sampling algorithm has extremely nice properties.

It is simple to implement and runs very ast in practice.

Moreover, there is a perormance guarantee associated with

the algorithm. This means that it gives solutions that are close

to the optimal solution or every data input. We are trying

to understand the behaviour o this simple sampling basedapproach or clustering at CSE, IIT Delhi. In the next section, we

talk about some o our results.

Dr. Ragesh Jaiswal

Assistant Proessor

Department o Computer Science and Engineering,


Pick the frst center randomly rom among the given points. Forthe ith center (i2), pick a point with probability proportional to

the square o the distance o this point to the nearest previously

chosen center.

A B

DC


8/16

8 | January 2013

Our results

Algorithms or streaming setting: The amount and speed

o generation o data has increased a lot in recent times.

Due to this, traditional model o data analysis where one

assumes that the data ts and stays in the memory during

the entire computation is becoming obsolete. The more

relevant setting is the streaming setting where the algorithm

is only allowed to make a pass (or ew passes) over the

data or analysis. So, in some sense, the algorithm should be

able to analyse a stream o data. One such scenario is analysing

stock prices on a light-weight machine such as a smart phone

or PDA that has limited memory and gets access to a stream o

data. In [Ailon, Jaiswal and Monteleoni, 2009] we design

algorithms or clustering or the streaming setting using the

sampling based approach. Our algorithm showed very goodresults on many datasets.

Behaviour or special datasets: Certain datasets have some

nice properties that can be exploited to get better clustering

results. One such property is that there is some degree o

separation between the clusters. In [Jaiswal and Garg, 2012]

and some on-going projects we show that the sampling based

clustering algorithm give very good results or such datasets.

Near accurate clustering algorithms: Since the k-means

clustering problem is believed to be hard, existence oefcient algorithms that produce optimal clustering is unlikely.

However, there may be algorithms that produce clustering

that is very close to the optimal. In [Jaiswal, Kumar and Sen,

2012], we design and analyse a very simple algorithm based on

the sampling approach that provably gives solutions that are

arbitrarily close to the optimal solution.

Hierarchical clustering: For certain data, the number o

clusters is not known beorehand. For instance, consider

nding clusters o riends in some social network dataset. In

such scenarios, we would like to cluster the data at all levels

o granularity so that i there is a query or producing varying

number o clusters, one can do that quickly. This is known as

Hierarchical clustering. In an on-going project, we are exploring

how the techniques and algorithms developed in [Jaiswal,

Kumar and Sen, 2012] can be used to give good Hierarchical

clustering algorithms.

Concluding remarks

The sampling based approach has lot o potential in designing

ast and accurate clustering algorithms. In various projects

being conducted at CSE, IIT Delhi, we hope to understand

the power o this approach and develop good clustering

algorithms.

Reerences

[Arthur and Vassilvitskii, 2007] David Arthur and Sergei1.

Vassilvitskii. k-means++: the advantages o careul seeding.

In Proceedings o the 18th Annual ACM-SIAM symposium

on Discrete Algorithms (SODA07), pp. 1027--1035, 2007.

[Ailon, Jaiswal and Monteleoni, 2009] Nir Ailon, Ragesh2.

Jaiswal and Claire Monteleoni. Streaming k-means

approximation. In Advances in Neural Inormation

Processing Systems (NIPS09), pp. 10-18, 2009.

[Jaiswal and Garg, 2012] Ragesh Jaiswal and Nitin Garg.3.

Analysis o k-means++ or separable data. In Proceedings

o the 16th International Workshop on Randomization and

Computation, pp. 591-602, 2012.

[Jaiswal, Kumar and Sen, 2012] Ragesh Jaiswal, Amit Kumar4.

and Sandeep Sen. A Simple D2-sampling based PTAS or

k-means and other Clustering Problems. In Proceedings o

the 18th Annual International Conerence on Computing

and Combinatorics, pp. 13-24, 2012.

Research in Dr. Sundars LabSundars lab has made signicant contribution in developing

strategies to evolve new DNA-binding specicity in zinc nger

proteins, especially in the area o zinc nger transcription actor

libraries, which has tremendous application in biomedicine. His

work was highlighted by Nature India in January 2011. Further

Sundars computational biology research employs the structure

and unction prediction tools developed by his group to help

guide experimentalists in manipulating proteins and extracting

inormation about their unction and structure, both at the singlemolecules as well as at the genomic / system levels.


9/16

January 2013 | 9

Faculty Proles

Pro. Vinod ChandraDepartment o ElectricalEngineering,Indian Institute o Technology,Delhi

Proessor Vinod Chandra completed his B. Tech in 1971 and

PhD in 1978 rom the department o Electrical Engineering at

IIT Delhi. He was appointed as the Senior Research Assistant

in 1971 in School o Radar Studies and Senior Scientic Ofcero CARE in 1974. He joined as Lecturer in the department o

Electrical Engineering at IITD in 1978 and was promoted as an

Assistant Proessor in 1981 and subsequently to the position

o Proessor in 1990. He was a Visiting Proessor in department

o Electrical and Computer Engineering at Florida Atlantic

University, Boca Raton, Florida, USA during 1987-1988.

He has developed the ollowing courses as part o his

teaching contributions: Fault Diagnosis in Digital Systems,

Testing and Fault Tolerance, Digital Communication and

Inormation Systems, Broad Band Communication andInormation Systems, Optical Communication Systems, Fiber

Optics and Optical Communication Lab. Along with other

aculty members he has been responsible or setting up a new

Photonics Laboratory in the institute.

He has made signicant research contributions in

development o electronic systems or various industries in

India. The innovative work has resulted in commercially viable

know-how and regular commercial production o several

microprocessor based electronic systems and instruments

in the area o Railway Electronics and Signalling. Themost signicant contribution is the development o AXLE

COUNTING SYSTEMS which are used or automatic signalling

in railways. The design and development o this system led to

the production o more than thousand equipments which are

in actual operational use in Indian Railways. This has resulted

in oreign exchange saving o approximately 75 crores.

These axle counter systems have been exported to Zambian

Railways against international competition. The successes

o these axle counters have also inspired the creation o new

R&D groups in saety electronics in Indian industry. Several

companies like M/s Crompton Greaves, DCM Data Products,Central Electronics Limited have taken this know how. Recently

RDSO has given a consultancy to IITD or improvement o

reliability o Axle Counting Systems or Block Working and

modications have lead to signicant perormance o these

systems in the eld.

As part o Photonics Mission, Technology Development

projects a FIBER OPTIC LAN FOR RAILWAY SIGNALLING

APPLICATIONS has been developed by him and his team

o students. This is a state o the art system or controlling

movement o trains in a sae manner in railway yards via optic

ber. An agreement on TECHNOLOGY TRANSFER or the

system developed by Pro. Vinod Chandra and his team has

been signed with M/s HBL Power Systems Ltd., Secunderbad,or total value o Rs. 20 lacs and the technology transer has

been completed. The rm has received a development order

rom Indian Railways and the rst system has been put on eld

trials at Falaknuma station in Hyderabad.

In addition to the above, several other electronic systems

developed by him have resulted in technology transer to the

industry. Together with above systems these innovations have

resulted in approximate production o about Rs. 100 crores

so ar. He has led a dozen sotware copyright applications

through FITT, IIT Delhi which have been approved to coverthe technology transers. He has also validated many railway

signalling systems rom the aspect o saety and reliability

and these have been accepted by RDSO or giving approval

to introduction o these systems in operational use in

Indian Railways.

He has guided six PhD theses and about ty M.Tech theses

and has published over ty papers in international journals

and conerence proceedings.

His current research is in the area o Optical Communicationand Optical Networks. He is currently guiding our research

scholars in this emerging area. Along with other aculty and

Axle Counter or Automatic Signalling in RailwaysNational Invention award 1979: Pro. P V Indiresan, Vinod Chandra, S VedanthamAxle counter is used or detecting the presence or absence o trains on the railwaytrack and is used or automatic signalling in railways. The system was developed atIIT Delhi in association with Research Design and Standards Organisation o IndiaRailways. The system is currently being manuactured by Central Electronics Ltd.,Sahibabad, who have installed over eight thousand systems in Indian Railways.


10/16

10 | January 2013

students, he has led two Indian patents on Optical Data

Vortex Interconnection Networks or applications in high

perormance computing. An application or US patent in this

area with application in Bi-directional Optical Interconnection

o high perormance computing in a highly scalable and ault

tolerant network, or connecting computers or sharing o data

and processing capabilities has been led.

Apart rom academic work, he has taken up administrative

responsibilities such as President, Board o Student Publications,

Co-ordinator o Interdisciplinary Optoelectronics and Optical

Communication program.

Pro. Vinod Chandra is recipient o the NRDC National

Inventions Award and was awarded 5

th

Hari Ramji Toshniwal

Proessor V. D. Vankar was born in Varanasi. His entireeducation was in Varanasi / Banaras Hindu University. He

got his PhD rom B.H.U. in 1975 on Small Angle Diraction

rom Thin Gold Films. He joined Thin Film Laboratory o

IIT Delhi as a Research Associate in 1976 and later became

the Lecturer in 1978, Assistant Proessor in 1985, Associate

Proessor in 1991, Proessor in 1995 and Proessor HAG

Scale in 2009.

He also had visiting assignments at Syracuse University, NY

and has been visiting UCLA, University o Caliornia San Diego,

Tokyo University etc.

Pro. Vankar has been teaching Electromagnetic Theory, Solid

State Physics, Thin Films Technology, Characterisation o

Materials etc. to undergraduate and Post Graduate students. His

research interests are in Nano-technology, Carbon Nanotubes

and Graphene Thin Films, Structure and Growth o Thin Films,

Plasma Processing o Materials, Solid Solid Interaces, Phase

Change Materials or Optical Recording, Hard Coatings,

Micro-crystalline Diamond, Diamond like Carbon and Surace

Physics. In these areas o research he has published about

more than 130 research papers in International Journals andone U.S. Patent on Boron Nitride and related coatings. He has

also developed several types o sputtering systems including

Memorial Award o the Institution o Electronics and

Telecommunication Engineers in the area o Electronics or

Application to Industry.

He has been actively participating in extension activities o

the institute and has conducted several short courses in areas

o Fault Tolerant Systems and Communication Systems. He

has also been involved with the Phase-I audit o Delhi Metro

along with other aculty colleagues rom the institute. He

was Member, Inter Departmental Technology Cooperation

Expert Group or Railway Signalling and Telecommunication,

DSIR, Ministry o Science and Technology. He was member o

high power Railway Saety Review Committee constituted by

Ministry o Railways, Government o India under the

Chairmanship o Justice H R Khanna.

Pro. V. D. VankarDepartment o Physics,Indian Institute o Technology,Delhi

Planar Magnetron sputtering systems, Plasma Assisted

Chemical Vapour Deposition systems in his laboratory.

Pro. Vankar has supervised 26 PhD students, 50 M.Tech and

about 12 M.Sc / B.Tech students or their thesis work. His

research work also presented in several National and

International Conerences / Workshops. Six o his papers got

Best Paper Awards too. At present six students are working

with him or PhD degree.

Pro. Vankar has been actively involved in the development

o various laboratories in Physics Department and has

created important research acilities therein. He was Principal

Investigator o several projects worth more than our crores.

He has been actively collaborating with important industries

such as Moserbear India Limited and other organization like

NPL, SSPL, IUAC etc.

Pro. Vankar is lie member o The Material Research Society o

India. He was also a member o Electron Microscope Societyo India, Indian Vaccum Society, Sigma Xi association o USA.

He was conerred with Material Research Society o India

(MRSI) Medal in 1997. He was invited to give several Invited

Lectures in various institutes / research laboratories / Theme

Conerences and workshop in India and abroad. He was

member o several important committees o CSIR / UGC / DRDO

/ National Laboratories / Institutes.

Pro. Vankar is very popular among his students. His students

have got prestigious jobs in India and all over the world, in

industries, National Laboratories and institutes etc. He is knownto be very conscientious person. He was a member o Society

or Scientic Values or three years.


11/16

January 2013 | 11

FITT / IIT Delhi Happenings

POSOCO Power System Awards (PPSA)2013Announced

To recognize the outstanding contributions made in the

eld o power sector, Power System Operation Corporation

(POSOCO), a wholly owned subsidiary o Power Grid

Corporation o India Ltd. (POWERGRID) in collaborationwith Foundation or Innovation & Technology Transer (FITT)

has taken the initiative to coner awards to innovations

and research works within the IITs and NITs to motivate

individuals and encourage urther research activities in

the area.

Under the Doctoral and Masters category a total o orty

awards are instrumented. An independent committee

consisting o representatives rom industry, academia and

research will evaluate the projects and make selection

or recognition. The top ten projects under the Doctoralcategory will be awarded with cash prize o Rs. 75,000 and

the remaining thirty under the Masters category will receive

cash o Rs. 35,000. Entries are open rom 1st o January 2013

to 31st January 2013.

Innovation Contest by EDCAnother innovation contest was organized by The Entrepreneurship Development Cellin

IIT Delhi on 29th November, 2012. There were ten teams in total, where each o the team

was assigned with news items ocusing on a particular issue. The task was to come up

with solutions and idea o the various issues, keeping in consideration the sustainability,technical easibility and easy implementation o the plan with general acceptance. Students Activity during the

2nd Innovation Contest

Annual General Meeting o FITT, October 31, 2012

Research and ViewsN. Ramakrishnan and R. Bose, Dipole entropy based1.

techniques or segmentation o introns and exons in

DNA Applied Physics Letter, Vol. 101, Iss. 8, 083701,

August 2012. This paper is currently eaturing in APL

website under Top Stories.

Link-http://apl.aip.org/eatures/top_stories

Coverage in the web-

http://www.eurekalert.org/pub_releases/2012-09/aiop-

ith091112.php

Roy, S., Dutta, S., Khanna, K., Singla, S. and Sundar,2.

D. (2012). Prediction o DNA-binding specicity in zinc

nger proteins. J. Biosciences 37(3):483-491

18th AGM o FITT

i3 Fair on 3rd December 2012The Indian Innovation Initiative, i3National fair was held

at IIT Delhi on 3rd December, 2012. This annual agship

initiative o the Department o Science & Technology DST

Government o India, Conederation o Indian Industry

(CII) and Agilent Technologies Ltd. was inaugurated by

Dr. Y S Rajan, Chairman o the National Board o Accreditation.

i3 mainly aims to give the country an innovative eco-systemat the same time providing innovators a unique platorm

with adequate unding, incubation, technology renement

and excellent marketing.

FITT in collaboration with the Government o Gujarat,

National Science and Technology Entrepreneurship

Development Board,

CII Technology

Development &

Promotion Center

(Tamil Nadu), WWF, YiYoung Indians, TIFAC

and India Angel

Network made this

event a huge success.

Cell phone based Indoor Navigation SystemRoshni or visually impaired individuals

developed by students o IIT, Delhi


12/16

12 | January 2013

Innovations

Opportunities or IP Licensing

Technology Proles

Sl. No. Title PI / Dept.

1 A surgical stapler Pro. Sneh Anand, CBME

2 An apparatus or measuring abric hand value Pro. Apurba Das, DTT

3 Wireless ECG patch and system or obtaining high denition mobile ECG Pro. Sneh Anand, CBME

4 A novel device and mechanism or mixing o uids Pro. S N Singh, AM

5Triple layer wound dressing material and mechanism or efcient drug release and

healing therebyPro. Veena Koul, CBME

6 Contra lateral limb controlled prosthetic knee joint Pro. Sneh Anand, CBME

7

Ionic liquid catalyst and a process or preparation thereo, and improved tertiary

butylation o phenol / phenolic compounds or higher conversion o phenol and

phenolic compounds

Pro. Sreedevi Upadhyayula,

CHEM

8 A system o generating rereshable tactile text and graphic Pro. P M V Rao, ME

9A novel closed loop speed control using carrier space vector pulse width modulated

direct torque control scheme or induction motor drivePro. J K Chatterjee, EE

10 Microbial process or removal o toxic phorbol esters rom de-oiled Jatropha seed cake Pro. S K Khare, Chemistry

11Power actor correction base 4D yback converter or permanent magnet brushless DC

motor drives or an applicationPro. Bhim Singh, EE

12Mechanical arm or transer o substrates under oxygen ree ambience between an

oxygen ree chamber and a thin lm coating system Pro. Viresh Dutta, CES

13Control strategy o optimum CNG uel injection or BSEC improvement and emission

(CO2

and NOx) reduction o a dual uel stationary diesel engine

Pro. K A Subramanian, CES

Sustainable Power Generation with GreenEnvironment using Diesel Engines with HybridFuels (CNG and Diesel)

Dr. K A Subramanian

Center or Energy Studies,


Diesel engines emit high level o oxides o nitrogen (NOx) and

particulate matter due to its combustion with heterogeneous

air-uel mixture. These emissions can be reduced signicantly

using compressed natural gas (CNG) which is injected into

intake maniold o diesel engine where as diesel as pilot uel

is directly injected into engine cylinder using conventional

injection system or initiating ignition o the air-uel charge. NOxand CO

2emissions decreased about 30% and 22% respectively

with 34% CNG energy share (1/3rd CNG and 2/3rd Diesel).

NOx emission can urther be reduced up to 60% with 2/3rd

CNG energy share but CO and HC emissions would increase.

Brake thermal efciency increased about 21% with 1/3rd o CNG

share. IIT Delhi has developed a technology entitled controlstrategy o CNG uel injection or dual uel diesel engine which

was unded by Department o Science and Technology (DST),

Government o India. This technology is basically a retrot gas

injection system to inject accurate and optimum quantity o

CNG share. This technology has an additional eature o system

exibility as it can be set the control strategy with optimum

CNG window based on required emission limit. The developed

electronic control unit (ECU) can also inject two gaseous uels

with independent control. The pilot uel can also be replaced

with renewable uel such as biodiesel and main CNG uel can

be derived rom variety o renewable source including biogasand producer gas resulting to sustainable power generation

with green environment.


13/16

January 2013 | 13

A Novel Purication Platorm or Cost EfectiveManuacturing o Therapeutic Proteins

Dr. Anurag S Rathore

Department o Chemical Engineering,


Eective and efcient manuacturing process is a critical

element o biopharmaceutical product development cycle. In

todays competitive market, besides being rst to the market,

quality and cost-eectiveness o the product are also key

drivers or process development. Downstream processing is an

integral part o any biopharmaceutical process which accounts

or up to 80% o the total manuacturing cost. Developing the

novel innovative processes is a key or the successul survivalo the biopharmaceutical companies in a highly competitive

market.

Present invention ocus on the developing single step

purication strategy or purication o cytokine class o the

biotherapeutic proteins. Recombinant human granulocyte

colony stimulating actor (rHu GCSF) was selected as a model

protein or the study. Proposed invention makes use o the single

step multimodal chromatographic purication or removal

o critical product related as well as various process related

impurities. Existing manuacturing process or GCSF involves

a combination o reolding and various chromatography steps

or removal o various product and process related impurities,

i.e. oxidized and reduced variants o native GCSF and Met

variants. Conversion o multistep purication platorm to the

single step purication process signicantly improved the

process productivity by 30 %.

FITT in collaboration with BIRACFITT has been selected as one o the three BIG partners in the country or implementation o Biotechnology Ignition Grant

(BIG) Scheme o Biotechnology Industry Research Assistance Council (BIRAC), a Government o India enterprise. The scheme is

designed to help establish and validate proo o concept and enable creation o spins o. The proposals under this scheme can

be submitted online rom January, 2013.

Short Course: Financing o Renewable Energy Technologies,December12-15, 2012

Certicate Programme: Telecom Technology & Management,August 2012- January 2013


14/16

14 | January 2013

R&D Projects

Sl. No. Title PI / Dept.

1Development o process o hardening or booster pump shat An alternative to hard

chrome plating Phase-IPro. J Bijwe, ITMMEC

2A process or the preparation o polymeric materials or composites and composite

polymer sheet and a sheet thereoPro. B L Deopura, TT

3 Study o grapheme as top layer contact material or silicon solar cells Pro. B R Mehta, Physics

4De-silting and rehabilitation o sewer barrels by CIPP technology along dierent line at

Q point in New DelhiPro. A K Keshari, CE

5 De-silting and rehabilitation o sewer line rom Bhai Veer Singh Marg to Sansad Marg Pro. A K Keshari, CE

6Research study on catalyst loading and its impact on the perormances o trickle bed

reactorsPro. K D P Nigam, CHEM

7 Benchmarking o plasma polymerized modied hollow bre membranes Pro. A K Ghosh, CPSE

8Design and development o 5-bit RF MEMS switched line phase shiter and LTCC

package or DMTL phase shiter (Phase-II)Pro. S K Koul, CARE

9 Graphite components in NAO riction material on NVH characteristics Pro. J Bijwe, ITMMEC

10

Determination o Mode o Filed Diameter (MFD) theoretical cut-o wave length, zero

dispersion wavelength (ZDW), macrobending loss, ber cut-o wavelength and cable

cut-o wavelength o a given bre reractive index prole

Pro. B P Pal, Physics

11 Examination o a saety intravenous catheter vis--vis Patent No. 240086 Pro. A Chawla, ME

12 Optimal water allocation network synthesis Dr. M A Shaik, CHEM

13 Basic design o pneumatic conveying system or yash Pro. V K Agarwal, ITMMEC

14 Technical inputs or pneumatic conveying o yash Pro. V K Agarwal, ITMMEC15 Exploration in machine learning and optimization or market applications Pro. Jayadeva, EE

16 Road saety political mapping in India Pro. G Tiwari, TRIPP

17 Comparison o LLDPE samples Pro. V Choudhary, CPSE

18 Dewatering scheme and design at additional building o Supreme Court Pro. A K Keshari, CE

19Development o some techniques / programs or educational sotware modules on

ber and integrated opticsPro. R K Varshney, Physics

20 Development o small molecules targeting cancer proteins Dr. N G Ramesh, Chemistry

21 Failure analysis o vibro-sieve and its re-design or extended lie Dr. R K Pandey, ME

22Recommendation or precision manuacturing process control and optimization

(Phase-II)

Dr. S Jha, ME

23Structural proteomics o plasmodium vivax development o a three-dimensional

structural dutubare o 500 soluble proteins in malaria paranitePro. B Jayaram, Chemistry

24 Development o sotware or underwater domain awareness (UDA) Phase-II Pro. R Bahl, CARE

25 Development o innovative ertilizers Regulating Nitrogen Delivery (RND) Pro. H M Chawla, Chemistry

26 Development o big-data analytics algorithms and models or mobile marketing Pro. S Chaudhury, EE

27Development o wear resident grades composites based on high perormance

polymersPro. J Bijwe, ITMMEC

28 Treatability study or the removal o chloride rom gelatin industry waste waters Pro. T R Sreekrishnan, DBEB

29 Image quality improvement or interventional X-ray imaging system Dr. K B Khare, Physics

30 Design o barrages o Nikki Tawi and Waddi Tawi over Tawi River, Jammu Pro. A K Keshari, CE

31Estimation o sub-surace hydraulic parameters or dewatering design or construction

o additional ofce complex or Supreme Court o IndiaPro. A K Keshari, CE


15/16

January 2013 | 15

Proessional Development Programmes

Forthcoming HRD Programmes (early 2013)#

Sl. No. Title DateSponsored/ Participation

Fee BasedFaculty / Dept.

1

Standardization and Measurement

o Custom Satisaction or ONGC

Executive

January

7-8, 2013ONGC, Vadodara Dr. Harish Hirani, ME

2

CEP course on Underwater

Superiority Technologies or

Underwater Acoustic Surveillance

January

17-19, 2013INS Valsura

Pro. R Bahl, CARE

Pro. Arun Kumar, CARE

3Advances Bridge Construction

Practices

January

28-30, 2013

Participation Fee Based Dr. Kumar Neeraj Jha, CE

4

2nd High Noon Spring School

Adaptation to Changing

Water Resources Availability in

Northern India with respect

to Himalayan Glacier Retreat

and Changing Monsoon Pattern

February

4- 7, 2013

UKaid Department or

International DevelopmentPro. A K Gosain, CE

5

Executive Development

Programme on Project

Management or IOCL Executive

February

11-16, 2013IOCL, Gurgaon Dr. S P Singh, DMS

6

Workshop on Development

in Renewable Energy Sources(Biomass, Solar etc.)

February

27-28, 2013 Participation Fee Based Pro. D K Sharma, CES

7

Training workshop

Discovery Development and

Commercialization o Biotech

Therapeutics

March

11-15, 2013PATH, New Delhi Pro. A K Gosain, CE

Proessional Candidate Registration Programme

Applications are invited rom qualied proessionals working

in industry and research organizations or a unique knowledgeaugmentation and skill enhancement programmes at IIT

Delhi. This involves a semester-long registration or a regular

PG course. Course ees ranges rom Rs. 15,000/- to Rs. 20,000/-

(industry proessionals) and Rs. 6,000/- to Rs. 8,000 (academic /

government personnel) or a 42 hour lecture course. In the case

o a ew selected courses, on-site course delivery using the two

way audio-video link can be considered.

All major disciplines o Science and Engineering, and also

relevant courses rom the Humanities, Social Sciences and

Management streams which are being conducted at IIT Delhiare covered. The course detail can be downloaded rom FITT

website www.tt-iitd.org.

Eligibility: Degree in Engineering or Masters Degree in Science,

Management or any other Post Graduate Degree with relevantindustry experience. The two semester sessions in the academic

year starts in the month o July and January, the exact dates

being notied in advance.

Contact: [email protected], [email protected].


16/16

Miscellaneous

Corporate Membership o FITTFITT invites the industry / industry associations / R&D

organizations and nancial institutions to become

corporate members o FITT at a nominal annual

subscription. A corporate client can participate in

technology transer and joint R&D programmes o the

Institute on a priority basis with FITT providing the

interace. Membership orm can be mailed on request or

can be downloaded rom www.tt-iitd.org.

Team

Chairman, Governing Council: Pro. R K Shevgaonkar, Director, IIT Delhi

Managing Director: Dr. Anil Wali

Executive Team: Sh. K K Roy, Sh. M Mahajan

Staf: Mrs. S Lamba, Sh. R K Mehta, Sh. V Bhattacharya, Sh. J Singh,

Sh. U Aswal, Sh. M K Rajoriya,

Consultant: Sh. G Kumar

Associates: Mr. D Sahu, Mr. N S Tomar, Ms. T Jain, Ms. S Bhuyan

Editing Desk: anilwali@tt iitd ac in surekha bhuyan@iitd ac in

Techno-Entrepreneurship SupportsFITT extends supports or innovation / entrepreneurship

under approved Government Schemes:

Technological Incubation and Development o

Entrepreneurs (TIDE), DIT: to nancially support

technology ventures (IT and IT & ES) at incubators during

early stages o their development (www.mit.gov.in).

Seed - Support to Incubatees, TDB: or addressing the

varied development needs o the start-ups at incubators up

to Rs. 25 lakhs (www.dsir.gov.in).

Biotechnology Ignition Grant (BIG) Scheme o BIRAC

(DBT): to establish and validate proo o concept through

nancial support / mentoring to incubatees and new

startups up to Rs. 50 lakhs (www.birapdbt.nic.in)

News and ViewsIIT-D All Set to Open Design Innovation Centre

A spate o new projects will soon grace the campus o the

Indian Institute o Technology (IIT Delhi). While the institute

has already set up its Student Innovation Centre with seed

unding provided by the batch o 1986, it is now ready to set

up yet another centre. The Government o India has approved

an innovation centre to be set up at the IIT campus. This is

going to be a design centre and will be dierent rom the

existing student innovation centre that already exists said,

R. K. Shevgaonkar, Director, IIT (Delhi).Sources: Hindustan Times, 26th October12

Foundation or Innovation and Technology Transer


Hauz Khas, New Delhi 110016

Phone: +91 11 26857762, 26597289,

26597153, 26597285, 26581013

Fax: +91 11- 26851169

Website: www.tt-iitd.org

Email: anilwali@tt iitd ac in mdtt@gmail com

Research at IIT-Delhi to get a booster dose: Director

IIT-Delhi plans to increase collaborations with oreign

universities. It wants to introduce ellowships or Ethiopian

students who wish to pursue a PhD. IIT-Delhi is also helping

the Mauritius government establish a research academy.

Source: The Indian Express, 27th October12

Transer land or extension campus, IIT Delhi tells Haryana

.The institute requested or an additional 100 acres in

Jhajjar. A six-member team rom IIT-Delhi visited plots in

Jhajjar to identiy the site or the second extension campus

Source: The Indian Express, 7th December12

Roshni: Indoor navigation system.

Students at IIT Delhi have created a navigation system based

on Global Positioning System that can work well i oor plans

o building are available.

Source: Hindustan Times, December12

Giveter.com: ex-IITians start-up helps people zero in on

the perect git

Source: The Economic Times, 10th December12

We spend only 0.9% o GDP on R&D

Research and development (R&D) is the basic constituent o

promoting innovation. The culture o research needs to be

urther augmented in our country. Only about 6,000 patent

applications were led by Indians in 2010, which is a mere 0.3

per cent o the total applications led in the world.Source: Business Standard, 16th December12

Nvidia, IIT Delhi collaborate on exascale computing

The new Exascale Research Lab (ERL), co-developed by

Nvidia and IIT Delhi, will help the nation achieve this goal by

providing advanced ongoing research, testing, and technology

development in a variety o areas, including processor

architecture, circuits, memory architecture, high-speed

signaling, programming models, algorithms, and applications.

Source: Times o India, 20th December12

FITT Newsletter Jan 13

Documents

Transcript of FITT Newsletter Jan 13