Entrez ID Gene Symbol Gene Name26821 SNORA74A small nucleolar RNA, H/ACA box 74A 9.37495384E-19 8.56495783E-15 14.2766 0.2020 1.2782 1.1069 0.2858 0.6419 0.6824652966 SNORD10 small nucleolar RNA, C/D box 10 1.74790762E-15 5.60311718E-13 12.4610 0.3852 4.2362 0.7988 0.6050 3.7688 0.35456043 SNORA63 small nucleolar RNA, H/ACA box 63 1.62578127E-13 1.1558862E-11 12.0957 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970677827 SNORA46 small nucleolar RNA, H/ACA box 46 1.55953445E-10 2.406741E-09 12.0626 0.1537 0.1651 0.1027 0.2313 0.0509 0.1317619565 SNORA52 small nucleolar RNA, H/ACA box 52 6.28158546E-13 3.06313506E-11 11.9368 0.6960 1.7337 1.2333 0.3785 1.3711 0.668754567 DLL4 delta-like 4 (Drosophila) 2.43274758E-09 2.51278484E-08 10.8857 1.1055 1.1948 1.8185 0.7463 1.0139 1.25806347 CCL2 chemokine (C-C motif) ligand 2 0.00185109693 0.004831891864 10.6363 0.1084 0.0696 0.1974 0.5384 0.1487 0.22733624 INHBA inhibin, beta A 8.51411334E-07 4.50274614E-06 10.6302 0.2710 0.5302 0.2694 0.3920 0.4079 0.2321677833 SNORA54 small nucleolar RNA, H/ACA box 54 1.54711549E-12 6.0793321E-11 10.5774 0.0680 0.0656 0.1802 0.1056 0.1168 0.2960100151684 RNU6ATAC RNA, U6atac small nuclear (U12-dependent splicing) 1.11887457E-10 1.82373561E-09 10.5195 1.6595 1.9716 2.4515 1.5896 2.4942 3.7519677820 SNORA38 small nucleolar RNA, H/ACA box 38 2.6699466E-14 3.36450099E-12 10.5082 0.3345 0.4209 0.4171 0.3755 0.5642 0.4356100170841 C17orf96 chromosome 17 open reading frame 96 9.88137918E-12 2.56831523E-10 10.4008 1.0604 1.8671 1.7254 0.7513 2.8064 1.86763976 LIF leukemia inhibitory factor 5.41639373E-09 5.04168855E-08 10.2622 1.0710 3.2237 1.8515 0.7005 4.2112 2.2054677840 SNORA71D small nucleolar RNA, H/ACA box 71D 3.78153621E-13 2.14584564E-11 10.2237 0.9288 7.0077 2.9628 0.5593 8.3386 1.8580677808 SNORA23 small nucleolar RNA, H/ACA box 23 9.96917944E-13 4.30838602E-11 10.1639 0.0478 0.1152 0.1205 0.2194 0.0367 0.1078112744 IL17F interleukin 17F 0.00037944624 0.001150936522 10.1484 0.0470 0.0458 0.1767 0.1106 0.0177 0.17143604 TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.18204562E-09 1.35667949E-08 9.9051 0.6921 2.2381 0.7928 0.4924 2.0138 0.4472677793 SNORA2A small nucleolar RNA, H/ACA box 2A 2.09555717E-12 7.68875918E-11 9.9025 0.1098 0.1604 0.2330 0.1462 0.0758 0.4275114599 SNORD15B small nucleolar RNA, C/D box 15B 4.70724229E-17 8.75611785E-14 9.7226 0.3156 2.1851 0.9223 0.4415 0.7860 0.603623413 NCS1 neuronal calcium sensor 1 1.34910607E-13 9.96419395E-12 9.5686 0.3011 0.7720 0.7031 0.4863 0.6165 0.8019677839 SNORA71C small nucleolar RNA, H/ACA box 71C 5.35580618E-12 1.61754199E-10 9.4152 0.3066 0.6899 1.0369 0.4347 0.6248 0.8721677829 SNORA49 small nucleolar RNA, H/ACA box 49 1.00990057E-14 1.67753666E-12 9.3306 0.0550 0.0509 0.2531 0.0960 0.0514 0.179526777 SNORA71A small nucleolar RNA, H/ACA box 71A 1.85141513E-12 6.97506337E-11 9.3209 0.1702 0.8446 0.7045 0.2828 0.1357 0.59226363 CCL19 chemokine (C-C motif) ligand 19 8.91644798E-09 7.7213904E-08 9.2923 0.1032 0.4056 0.2613 0.2456 0.2196 0.33779997 SCO2 SCO2 cytochrome c oxidase assembly protein 5.17890036E-09 4.8552523E-08 9.2707 1.4059 4.1722 1.8663 1.1360 4.4879 2.1884

10501 SEMA6B 0.00017559366 0.000571101357 9.2286 0.1049 0.1362 0.1478 0.3885 0.1418 0.18501846 DUSP4 dual specificity phosphatase 5 4.22465272E-12 1.34015372E-10 9.2248 1.9009 2.4293 1.4155 1.1280 6.7284 3.633651330 TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.31041092E-09 2.394545E-08 9.1334 2.3143 1.7131 2.0052 0.9497 1.2007 2.1827692225 SNORD94 small nucleolar RNA, C/D box 94 2.00479401E-11 4.56184261E-10 9.1197 0.0273 0.0164 0.1898 0.1463 0.0233 0.1291677766 SCARNA2 small Cajal body-specific RNA 2 8.96476707E-17 1.3650352E-13 9.0812 1.9529 1.1691 1.6154 1.5906 1.5306 2.592780728 ARHGAP39 Rho GTPase activating protein 39 1.69901466E-07 1.06718446E-06 9.0264 0.8561 2.7974 1.6085 0.6031 1.9540 1.13368645 KCNK5 potassium channel, subfamily K, member 5 1.55043247E-09 1.70968631E-08 9.0188 0.9061 1.7781 1.7901 0.9105 2.1382 2.0184677841 SNORA74B small nucleolar RNA, H/ACA box 74B 5.25615199E-11 9.80004175E-10 8.9774 0.2377 0.2813 0.3149 0.4698 0.4504 0.1995724102 SNHG4 small nucleolar RNA host gene 4 (non-protein coding) 1.73321102E-06 8.58710189E-06 8.9661 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970114614 MIR155HG MIR155 host gene (non-protein coding) 2.88721979E-11 6.0988763E-10 8.8756 1.7566 2.0526 1.7191 1.3376 2.9648 1.8207677772 SCARNA6 small Cajal body-specific RNA 6 5.88293707E-13 2.99771164E-11 8.7795 0.1173 0.1089 0.1918 0.1793 0.2357 0.2336677843 SNORA77 small nucleolar RNA, H/ACA box 77 1.1236558E-06 5.78676403E-06 8.7302 0.1269 0.0309 0.1491 0.1179 0.0722 0.1921692158 SNORA57 small nucleolar RNA, H/ACA box 57 1.08304855E-10 1.77643295E-09 8.7291 0.3321 0.3321 0.3321 0.3970 0.3970 0.397064493 LINC00235 long intergenic non-protein coding RNA 235 6.42947937E-13 3.1161657E-11 8.6843 1.4488 4.3971 2.5072 0.8458 7.5044 1.95643558 IL2 interleukin 2 7.29942512E-07 3.92395104E-06 8.6568 1.3630 1.1832 0.6539 0.8670 1.7367 0.323810148 EBI3 Epstein-Barr virus induced 3 6.51490423E-09 5.90770869E-08 8.5952 0.0816 0.6131 1.8434 0.0767 0.3687 0.916929763 PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.67490379E-10 5.02603608E-09 8.5096 1.6834 2.4412 2.8243 0.7056 2.2559 2.09718355 HIST1H3G histone cluster 1, H3g 1.43930547E-07 9.1826081E-07 8.5070 2.5470 2.2146 3.4349 1.8776 1.4697 4.27701852 DUSP9 dishevelled segment polarity protein 1 4.27197716E-07 2.42490111E-06 8.5056 0.5424 1.9722 0.7258 0.5437 0.8030 0.5574692086 SNORD17 small nucleolar RNA, C/D box 17 3.32508916E-14 3.97098229E-12 8.4343 3.7854 2.3361 2.2028 3.1229 1.1183 1.082526776 SNORA71B small nucleolar RNA, H/ACA box 71B 1.89273182E-11 4.36115963E-10 8.4273 0.1536 0.4574 0.3189 0.1766 0.5025 0.34909088 PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 1.91190781E-08 1.52153221E-07 8.3778 0.4195 1.6922 1.2824 0.4490 1.6941 1.48296367 CCL22 chemokine (C-C motif) ligand 22 1.73831302E-07 1.08775532E-06 8.3368 0.0816 0.3805 0.6901 0.0692 0.2029 0.474526024 PTCD1 pentatricopeptide repeat domain 1 3.14631253E-10 4.4019466E-09 8.3004 0.2682 1.7402 2.8189 0.0773 4.5536 1.26826079 SNORD15A small nucleolar RNA, C/D box 15A 5.86975279E-11 1.07359482E-09 8.2980 1.3967 3.2732 4.1435 0.9612 3.0656 2.6318

2030 SLC29A1 1.75091565E-09 1.89755224E-08 8.2863 0.8234 2.1159 1.9041 0.6370 2.0677 1.13887004 TEAD4 TEA domain family member 4 9.57302122E-06 4.03688539E-05 8.2844 0.7543 0.8410 1.9412 0.7374 0.1883 1.9262677847 SNORA81 small nucleolar RNA, H/ACA box 81 4.24526051E-10 5.65787017E-09 8.2830 0.3321 0.3321 0.3321 0.3970 0.3970 0.39703596 IL13 interleukin 13 1.25748588E-05 5.17040276E-05 8.2267 0.1913 0.3249 0.7347 0.4614 0.1859 0.3186990 CDC6 cell division cycle 6 4.37052444E-08 3.17654028E-07 8.2042 1.0197 1.6198 1.4255 0.6517 2.7445 1.6612677832 SNORA53 small nucleolar RNA, H/ACA box 53 8.28362974E-13 3.76513638E-11 8.2031 0.2032 0.2256 0.4004 0.4867 0.1557 0.2934677776 SCARNA8 small Cajal body-specific RNA 8 1.91812494E-09 2.0507887E-08 8.1768 0.0988 0.0388 0.1294 0.2538 0.1568 0.33944681 NBL1 neuroblastoma 1, DAN family BMP antagonist 3.67113667E-10 5.02603608E-09 8.1602 0.6074 1.0650 1.1844 0.4008 0.9077 0.9805619562 SNORA3 small nucleolar RNA, H/ACA box 3 3.46326424E-09 3.42799373E-08 8.0352 2.1206 1.9992 2.9771 0.8278 3.6862 2.96916383 SDC2 syndecan 2 0.00076236849 0.002169443547 8.0037 0.2930 1.1350 0.7820 0.2417 0.6549 0.5360677765 SCARNA18 small Cajal body-specific RNA 18 6.91888013E-09 6.20322756E-08 7.9905 0.3576 0.3800 0.1832 0.3534 0.1528 0.21193578 IL9 interleukin 9 0.00014299465 0.000475483674 7.9500 0.0377 0.1844 0.1212 0.0935 0.0585 0.1173677815 SNORA34 small nucleolar RNA, H/ACA box 34 8.0402266E-12 2.20587118E-10 7.9141 0.0977 0.1440 0.1214 0.1721 0.1310 0.19504917 NTN3 netrin 3 4.37089421E-07 2.47720158E-06 7.8562 0.3049 0.4202 0.9368 0.4171 0.4624 0.57282342 FNTB farnesyltransferase, CAAX box, beta 2.55718717E-07 1.53397649E-06 7.8538 1.5276 1.2495 1.7350 1.7661 2.0514 2.488010563 CXCL13 chemokine (C-X-C motif) ligand 13 0.00167211405 0.004415154317 7.8509 0.0551 0.0217 0.0956 0.2212 0.0745 0.1565100191040 C2CD4D C2 calcium-dependent domain containing 4D 2.34699236E-08 1.82176059E-07 7.8300 1.0399 1.0835 1.4014 0.6485 0.7769 1.142851083 GAL galanin/GMAP prepropeptide 9.26877578E-06 3.92307323E-05 7.8023 0.5118 0.7746 0.7264 0.3046 1.3188 0.59226364 CCL20 chemokine (C-C motif) ligand 20 3.6008747E-06 1.66359501E-05 7.7955 0.2089 0.6231 0.6084 0.2789 0.7974 0.480455388 MCM10 minichromosome maintenance complex component 10 6.90048533E-09 6.19585592E-08 7.7917 1.1565 3.0679 1.6512 0.5685 1.8996 1.64748294 HIST1H4I histone cluster 1, H4i 6.52644984E-12 1.87797309E-10 7.7795 2.6302 2.1650 1.6735 2.4194 1.7269 2.25224171 MCM2 minichromosome maintenance complex component 2 1.35386329E-10 2.1303133E-09 7.7724 0.4885 0.7844 1.1930 0.6010 0.6156 0.96381869 E2F1 E2F transcription factor 2 4.87954588E-09 4.62203537E-08 7.7585 0.8742 1.5233 1.3461 0.4950 1.7441 1.272029128 UHRF1 ubiquitin-like with PHD and ring finger domains 1 4.29413625E-10 5.70221349E-09 7.7334 1.6045 2.7308 1.6878 0.9283 2.5097 1.7508677834 SNORA55 small nucleolar RNA, H/ACA box 55 5.23574177E-08 3.71874472E-07 7.6748 0.0611 0.2398 0.2767 0.1051 0.0817 0.3493677805 SNORA18 small nucleolar RNA, H/ACA box 18 1.39270489E-09 1.55928332E-08 7.6442 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970100124536 SNORA38B small nucleolar RNA, H/ACA box 38B 3.64649666E-12 1.19406428E-10 7.6155 0.0656 0.0513 0.0552 0.2006 0.1077 0.18361437 CSF2 colony stimulating factor 2 (granulocyte-macrophage) 6.31877462E-05 0.000226119565 7.5581 0.1804 0.5263 1.5624 0.1438 0.6804 0.906684842 HPDL 4-hydroxyphenylpyruvate dioxygenase-like 1.43338314E-09 1.59408258E-08 7.5533 1.2088 2.4314 1.8083 0.9524 3.4676 1.6112652965 SNORA48 small nucleolar RNA, H/ACA box 48 2.41656855E-13 1.5883288E-11 7.5264 1.2783 3.4220 2.0073 0.8759 3.9584 1.436151514 DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 5.81587969E-08 4.07937634E-07 7.5165 2.1756 2.0059 2.8493 2.6294 1.1038 1.81918358 HIST1H3B histone cluster 1, H3b 3.41405747E-09 3.38295325E-08 7.5129 1.7152 3.8422 2.2675 0.7905 2.3214 2.19576510 SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.1994833E-12 4.94739478E-11 7.4755 1.5433 1.3339 1.9071 0.8310 2.3472 2.94121440 CSF3 colony stimulating factor 3 (granulocyte) 0.00046741486 0.001388039061 7.4679 0.0395 0.0472 0.2598 0.1781 0.0293 0.264928231 SLCO4A1 solute carrier organic anion transporter family, member 4A1 5.9122077E-10 7.50714795E-09 7.4576 0.4353 1.1051 1.1568 0.3947 1.1335 1.4106283869 NPW neuropeptide W 5.18018505E-05 0.00018832539 7.4042 0.2000 0.3775 0.8682 0.2075 0.4417 0.557792659 MAFG-AS1 MAFG antisense RNA 1 (head to head) 4.88549922E-08 3.49658605E-07 7.3928 0.8796 20.3625 6.4965 0.3074 7.5803 4.59097293 TNFRSF4 tumor necrosis factor receptor superfamily, member 4 4.21983038E-10 5.63219436E-09 7.3712 1.4014 2.4437 1.8263 0.9381 2.2325 1.7849286207 C9orf117 chromosome 9 open reading frame 117 6.82112067E-07 3.68962454E-06 7.3450 0.1509 0.2463 0.4502 0.1078 0.3140 0.3529

8482 SEMA7A 2.47854879E-10 3.60286742E-09 7.3257 1.3647 2.3211 2.2880 0.7912 2.0357 2.38388973 CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.83121562E-05 0.000108112794 7.3095 1.8098 1.5003 1.5194 0.7310 0.9242 0.82861961 EGR4 early growth response 4 1.00014607E-05 4.2020393E-05 7.3058 1.2110 1.2732 1.1368 0.9065 0.6617 1.307951450 PRRX2 paired related homeobox 2 1.85071354E-05 7.34975828E-05 7.2997 1.3933 1.3612 0.8757 0.8770 0.6473 0.61365831 PYCR1 pyrroline-5-carboxylate reductase 1 2.54408567E-10 3.68348124E-09 7.2823 0.8659 2.0357 1.4661 0.4428 1.7700 1.362759067 IL21 interleukin 21 0.00023738376 0.000752903331 7.2582 0.2910 0.5546 0.8432 0.1904 0.2949 0.44338784 TNFRSF18 tumor necrosis factor receptor superfamily, member 18 3.89961683E-11 7.67821108E-10 7.2511 0.4663 2.0929 1.8185 0.1894 2.8966 1.8408645027 EVPLL envoplakin-like 0.00010296888 0.000352991991 7.1921 0.2704 0.2738 0.2730 0.3062 0.0400 0.202778999 LRFN4 leucine rich repeat and fibronectin type III domain containing 4 4.48176134E-12 1.40223875E-10 7.1675 1.9154 1.3312 1.1089 1.4179 1.0145 1.3872677777 SCARNA12 small Cajal body-specific RNA 12 1.29270503E-13 9.72029064E-12 7.1475 0.2328 0.5463 0.8926 0.5166 0.5068 0.4858100124539 SNORA11B small nucleolar RNA, H/ACA box 11B 1.18068614E-08 9.88702894E-08 7.1297 0.1762 0.2209 0.3679 0.3227 0.0951 0.3991677781 SCARNA16 small Cajal body-specific RNA 16 3.48478966E-13 2.02320155E-11 7.1186 0.6476 1.1986 3.1641 1.8432 0.6208 1.2621404217 CTXN1 cortexin 1 3.92652404E-06 1.79723064E-05 7.1153 0.4587 0.8080 1.0361 0.3322 0.5587 0.918554997 TESC tescalcin 1.17676338E-10 1.90281596E-09 7.0853 1.7050 2.4704 1.7901 0.8696 1.1881 2.0148150771 ITPRIPL1 inositol 1,4,5-trisphosphate receptor interacting protein-like 1 8.47121096E-12 2.27961659E-10 7.0667 1.4564 1.3477 2.2929 1.0673 1.6419 2.09488877 SPHK1 sphingosine kinase 1 1.15114967E-12 4.81322811E-11 7.0630 0.8072 1.7032 0.9286 0.3718 1.7247 0.87683559 IL2RA interleukin 2 receptor, alpha 1.67858896E-13 1.17966068E-11 7.0519 0.8843 1.0736 1.3314 0.9028 2.1956 1.559680178 C16orf59 chromosome 16 open reading frame 59 2.35757297E-09 2.44203931E-08 7.0392 0.8876 1.2784 1.5960 0.7183 0.7798 1.3858100302240 MIR1304 microRNA 1304 2.16271083E-06 1.04653211E-05 7.0338 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970128506 OCSTAMP osteoclast stimulatory transmembrane protein 0.01121255327 0.02386716838 7.0323 0.0558 0.2197 0.7122 0.3451 0.1884 0.4512

1468 SLC25A10 1.64794845E-10 2.51766841E-09 7.0018 0.6035 1.1017 0.7833 0.5025 1.6167 0.9161653604 HIST2H3D histone cluster 2, H3d 1.04633724E-11 2.69804405E-10 6.9819 0.7964 0.6490 0.9588 0.5731 0.7457 0.65525133 PDCD1 programmed cell death 1 2.92942046E-08 2.20909495E-07 6.9767 0.4618 1.1428 1.1347 0.2689 0.7664 1.00489700 ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 1.42718217E-08 1.1742189E-07 6.9729 1.1976 0.6213 1.2714 0.9108 0.5816 1.1261389333 PROB1 proline-rich basic protein 1 3.53815037E-09 3.49077125E-08 6.9564 1.0780 4.2510 1.5289 1.0249 3.8396 1.31833662 IRF4 interferon regulatory factor 4 1.5391059E-12 6.07398337E-11 6.9228 1.0077 2.4794 2.3461 1.1036 2.4035 2.56278318 CDC45 cell division cycle 45 2.65336801E-08 2.0285498E-07 6.8872 0.5734 1.4760 2.5446 0.7217 1.8323 2.05347087 ICAM5 intercellular adhesion molecule 5, telencephalin 1.0931391E-06 5.65030767E-06 6.8310 1.5361 2.2554 2.5384 0.9883 1.3663 2.29454312 MMP1 matrix metallopeptidase 1 (interstitial collagenase) 6.5451949E-05 0.000233536031 6.8289 0.0448 0.0385 0.1090 0.2965 0.0873 0.1385677679 SCARNA3 small Cajal body-specific RNA 3 5.46922433E-08 3.85844274E-07 6.8118 0.1999 0.1497 0.1906 0.5881 0.0256 0.2200677813 SNORA30 small nucleolar RNA, H/ACA box 30 7.18482631E-06 3.11387918E-05 6.7952 0.0752 0.0890 0.2400 0.3450 0.0194 0.190854663 WDR74 WD repeat domain 74 1.57829137E-12 6.16208118E-11 6.7777 2.4135 3.3194 2.9279 1.7496 3.5186 2.8956348180 CTU2 hypothetical protein LOC348180 3.76246429E-12 1.22109676E-10 6.7522 0.3751 1.0726 2.6634 0.6770 0.2767 0.6178118430 MUCL1 mucin-like 1 0.00206454858 0.005338725119 6.7433 0.1379 0.2132 0.4308 0.3172 0.0864 0.17948704 B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 4.79737164E-11 9.10255189E-10 6.7426 0.5339 0.5775 1.2618 0.1115 0.3956 0.8094149473 CCDC24 coiled-coil domain containing 24 5.97229846E-06 2.63080611E-05 6.7410 1.4567 1.4048 1.2677 1.3786 1.1922 1.2479100124534 SNORA84 small nucleolar RNA, H/ACA box 84 3.31737448E-11 6.7575325E-10 6.7311 1.8522 3.3356 2.6401 1.3306 5.0697 1.7272598 BCL2L1 BCL2-like 1 3.55994401E-16 2.32311775E-13 6.7101 1.9639 2.3535 1.7579 1.9227 4.8007 3.4340993 CDC25A cell division cycle 25A 1.84651184E-06 9.09174464E-06 6.7017 1.5322 1.3885 1.2941 1.2813 1.3635 1.9716140831 ZSWIM3 zinc finger, SWIM-type containing 3 2.99303476E-10 4.22960024E-09 6.6979 2.2958 0.5972 1.1087 3.8417 0.3530 0.7449677882 SNORA59B small nucleolar RNA, H/ACA box 59B 8.26406816E-08 5.59885256E-07 6.6920 0.4808 0.6023 0.5446 0.4977 0.2763 0.35723196 TLX2 T-cell leukemia homeobox 2 3.00059727E-06 1.40762293E-05 6.6877 0.4614 0.8561 1.3501 0.2411 0.3976 0.9022246778 IL27 interleukin 27 2.90852347E-05 0.000110787035 6.6821 0.1601 0.3912 0.3724 0.2140 0.1465 0.20324998 ORC1 origin recognition complex, subunit 1 1.65609239E-08 1.33716836E-07 6.6785 8.2762 1.7240 2.4840 2.5894 1.1185 9.1910133690 CAPSL calcyphosine-like 7.9992801E-07 4.25262863E-06 6.6647 0.2340 0.0436 0.2293 0.1805 0.0455 0.1758

Supplementary Table S1-Naive CD4 T cells: Genes significantly differentially expressed 1 Day after activation in naïve CD4 T cells as determined by RNA-Seq (FDR<0.05, Log2 Fold Change >1 or <-1). Total enrichment (defined by FPKM of each modification relative to input) of genes at each time point for promoter H3K4me2 and H3K4me3 (1 kb surrounding the TSS) is also included at rest, 1 day, and 5 days after activation. Selected genes with particular relevance to T cell function are bolded.

RNA-Seq Resting vs 1 day P-value

RNA-Seq Resting vs 1

Day FDR

RNA-Seq Resting vs 1 Day Log2 Fold

Change

Naïve Resting H3K4me2/input

FPKM

Naïve 1 Day H3K4me2/input

FPKM

Naïve 5 Days H3K4me2/input

FPKM

Naïve Resting H3K4me3/input

FPKM

Naïve 1 Day H3K4me3/input

FPKM

Naïve 5 Days H3K4me3/input

FPKM

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B

solute carrier family 29 (equilibrative nucleoside transporter), member 1

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10

8811 GALR2 galanin receptor 2 1.29724413E-09 1.47408239E-08 6.6547 0.7900 0.9250 1.2348 0.6635 0.5151 0.593679412 KREMEN2 kringle containing transmembrane protein 2 1.03249539E-05 4.32400158E-05 6.6313 1.7722 2.3074 1.4992 0.8643 1.1468 1.1615113828 FAM83F family with sequence similarity 83, member F 1.21389878E-05 5.00911439E-05 6.6216 0.8382 1.5431 1.2346 0.4290 1.0331 1.059757464 STRIP2 striatin interacting protein 2 5.13991186E-12 1.57050952E-10 6.5993 0.7626 1.0022 0.9741 0.7055 1.1954 1.402910457 GPNMB glycoprotein (transmembrane) nmb 0.02238862 0.04348728231 6.5915 0.1042 0.2572 0.2838 0.1700 0.1157 0.2120100272217 LOC100272217 uncharacterized LOC100272217 6.12117082E-05 0.000219693642 6.5762 0.3469 3.7616 0.8402 0.2590 0.4751 0.142379075 DSCC1 DNA replication and sister chromatid cohesion 1 2.23244814E-08 1.74695042E-07 6.5532 1.2873 2.0717 1.9532 0.8114 2.4167 2.1776677810 SNORA26 small nucleolar RNA, H/ACA box 26 3.53029443E-09 3.48490221E-08 6.5532 0.9060 3.6184 2.8370 0.4529 3.2683 1.5245113130 CDCA5 cell division cycle associated 5 1.46116807E-07 9.30584281E-07 6.5457 0.2269 1.5713 3.2306 0.1503 2.4664 1.064064146 PDF peptide deformylase (mitochondrial) 2.09607103E-09 2.20491709E-08 6.5383 0.9525 2.2283 1.8099 0.8771 3.1209 2.5253130612 TMEM198 transmembrane protein 198 2.05733199E-07 1.26784385E-06 6.5378 0.2796 0.6124 0.4456 0.3332 0.2635 0.40214323 MMP14 matrix metallopeptidase 14 (membrane-inserted) 8.69149025E-05 0.000303016428 6.5052 1.4873 1.7134 1.0440 1.0078 1.1001 0.57779957 HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00019626574 0.000631946032 6.4661 1.3634 1.0550 1.8054 1.0958 0.8466 1.22076385 SDC4 syndecan 4 1.60691576E-10 2.46943353E-09 6.4489 0.7255 1.6044 1.9050 0.5414 1.4868 1.785726778 SNORA70 small nucleolar RNA, H/ACA box 70 1.89596015E-08 1.51147399E-07 6.4227 0.3603 2.4086 0.3633 0.1025 0.6103 0.213326780 SNORA68 small nucleolar RNA, H/ACA box 68 2.46030219E-09 2.53408352E-08 6.4154 0.3528 1.0659 0.9762 0.2906 2.2160 0.548489958 SAPCD2 suppressor APC domain containing 2 2.34697394E-08 1.82176059E-07 6.3994 0.9014 1.4979 1.6191 0.2779 0.5483 1.68561594 CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 3.13733243E-08 2.34555394E-07 6.3926 0.9857 2.2953 1.7837 0.6258 2.5589 1.8731114787 GPRIN1 G protein regulated inducer of neurite outgrowth 1 8.63071158E-08 5.81920155E-07 6.3906 1.0615 1.3044 0.9574 1.0049 2.1905 1.2263414062 CCL3L3 chemokine (C-C motif) ligand 3-like 3 0.0030770469 0.007639103388 6.3889 0.3586 0.2190 0.2182 0.4427 0.2580 0.2807692223 SNORD97 small nucleolar RNA, C/D box 97 3.25696467E-12 1.08597187E-10 6.3718 0.8593 0.9765 0.4828 0.6872 0.8083 0.512123612 PHLDA3 pleckstrin homology-like domain, family A, member 3 2.43660483E-07 1.47130349E-06 6.3546 0.2825 1.6429 1.5897 0.3652 0.5985 1.8396388610 TRNP1 TMF1-regulated nuclear protein 1 5.1318184E-05 0.000186715623 6.3477 1.6065 2.2720 1.6911 0.7192 0.9577 1.52269319 TRIP13 thyroid hormone receptor interactor 13 6.51843108E-08 4.53042118E-07 6.3425 2.2551 1.8047 3.1945 1.5488 1.4811 1.0407943 TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.10536946E-05 4.59970639E-05 6.3412 0.7051 1.2132 1.6346 0.4525 1.1217 0.94177124 TNF tumor necrosis factor 3.71955283E-09 3.6461196E-08 6.3294 0.5224 0.5494 0.5784 0.5033 0.5595 0.5918644815 FAM83G family with sequence similarity 83, member G 4.96452826E-13 2.65326755E-11 6.3248 1.0364 1.9035 1.1196 0.9854 2.2830 1.34107421 VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 2.23668855E-12 8.00539693E-11 6.3110 1.9068 2.6433 2.2349 1.2756 1.8332 2.9179677830 SNORA50 small nucleolar RNA, H/ACA box 50 5.56005512E-10 7.11437865E-09 6.3036 0.1912 0.0654 0.1742 0.2443 0.0419 0.176826155 NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 1.66141812E-15 5.51953307E-13 6.3015 0.8126 1.0687 0.8464 0.7585 1.5192 1.132710999 SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 1.0975788E-13 8.50641606E-12 6.2993 1.8914 1.4154 1.9906 1.4045 2.0959 1.9990375790 AGRN agrin 2.8991904E-11 6.11003541E-10 6.2935 1.0438 1.2580 1.0418 0.7155 2.3570 0.930083543 AIF1L chromosome 9 open reading frame 58 1.50246273E-06 7.53375384E-06 6.2886 0.6344 0.7090 0.6744 0.5783 0.9903 0.52402194 FASN fatty acid synthase 1.43813773E-12 5.78802921E-11 6.2880 0.3596 0.6100 0.6452 0.2815 1.1394 1.4397151473 SLC16A14 solute carrier family 16, member 14 2.60000105E-05 9.99941469E-05 6.2866 2.2108 1.8619 1.3450 1.4261 1.3698 1.51494884 NPTX1 neuronal pentraxin I 5.56912441E-05 0.000201343572 6.2859 1.3407 1.7093 1.9866 0.6129 2.0755 1.1749

8140 SLC7A5 3.57750451E-11 7.17542947E-10 6.2763 1.8384 1.1000 1.3829 1.5710 2.8560 1.78832669 GEM GTP binding protein overexpressed in skeletal muscle 1.52005268E-07 9.6505916E-07 6.2738 1.4005 1.1404 2.2370 1.1873 1.0388 1.86613090 HIC1 hypermethylated in cancer 1 6.73340684E-10 8.37527637E-09 6.2587 1.4316 1.6150 1.9297 0.7934 1.3663 2.04319811 CTIF CBP80/20-dependent translation initiation factor 2.46243729E-08 1.90006985E-07 6.2542 0.8676 1.0123 0.8697 0.5734 0.7644 0.934730009 TBX21 T-box 21 1.4239211E-08 1.17250502E-07 6.2336 1.6230 2.3666 1.7572 0.8588 2.4898 1.9203124222 PAQR4 progestin and adipoQ receptor family member IV 6.92522549E-13 3.32994001E-11 6.2281 1.2900 1.1182 1.4512 0.8690 0.8897 1.93183732 CD82 CD82 molecule 2.69087859E-16 2.04865557E-13 6.2072 1.3230 1.7184 1.5481 1.0402 2.1097 2.075781621 KAZALD1 Kazal-type serine peptidase inhibitor domain 1 3.86419003E-05 0.000144242044 6.1843 1.5127 2.2860 2.1476 1.5503 2.4660 2.4656

5881 RAC3 1.01533384E-07 6.7047994E-07 6.1796 1.4315 3.1762 1.7587 1.0687 3.1659 2.54176696 SPP1 secreted phosphoprotein 1 0.00070919958 0.002027933435 6.1713 0.2890 1.0645 0.3852 0.2556 0.2955 0.2481114987 WDR31 WD repeat domain 31 0.0003196166 0.000987493155 6.1366 1.9199 1.9430 1.7466 1.6347 2.0775 1.78504796 TONSL tonsoku-like, DNA repair protein 8.54119443E-10 1.02337511E-08 6.1364 1.1518 1.8279 1.6639 0.5985 1.9040 1.99755309 PITX3 paired-like homeodomain 3 0.00019066243 0.000615292113 6.1189 1.2751 1.5151 1.6797 0.7711 0.8267 1.247778995 C17orf53 chromosome 17 open reading frame 53 7.13136195E-08 4.91158106E-07 6.1136 0.7061 1.0946 0.9699 0.6205 0.7085 0.9104165904 XIRP1 cardiomyopathy associated 1 0.0001010623 0.000347107216 6.1128 0.1640 0.1387 0.3724 0.4508 0.0966 0.313755083 KIF26B kinesin family member 26B 2.79400284E-05 0.00010693762 6.0976 0.5361 0.5613 0.9513 0.4669 0.4520 0.66465198 PFAS phosphoribosylformylglycinamidine synthase 3.06515344E-12 1.02953095E-10 6.0925 0.7606 0.7397 0.8169 0.7812 1.0422 0.80953164 NR4A1 nuclear receptor subfamily 4, group A, member 1 2.19917051E-08 1.72460273E-07 6.0901 0.9469 2.1353 1.0761 0.7412 1.6330 1.14768360 HIST1H4D histone cluster 1, H4d 2.09493333E-12 7.68875918E-11 6.0802 1.8304 1.3002 2.5552 1.6830 0.8958 1.6740677771 SCARNA4 small Cajal body-specific RNA 4 2.13123965E-09 2.23676111E-08 6.0790 0.1368 0.2534 0.2094 0.1777 0.0730 0.3393319103 SNORD8 small nucleolar RNA, C/D box 8 2.02438202E-09 2.13935849E-08 6.0788 0.0398 0.0875 0.0686 0.2069 0.0162 0.1439991 CDC20 cell division cycle 20 1.58777793E-08 1.28941681E-07 6.0502 1.5108 1.9310 2.3957 1.1202 1.8991 2.5412140809 SRXN1 sulfiredoxin 1 homolog (S. cerevisiae) 5.25966279E-09 4.92338927E-08 6.0498 0.5671 0.7676 0.9712 0.4961 0.7858 0.84036697 SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.00026957739 0.000846488744 6.0468 1.1102 1.9559 1.5454 0.7060 1.4892 1.19832786 GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.00027149289 0.000851333132 6.0384 1.1569 2.0786 1.0273 0.6080 1.2414 0.87131152 CKB creatine kinase, brain 3.15175897E-09 3.15037964E-08 6.0291 1.2818 1.8307 0.8772 0.8256 0.8266 0.8216342132 ZNF774 zinc finger protein 774 0.00019998244 0.000643210549 6.0283 1.2783 1.9546 1.5765 1.0438 2.0798 1.882379170 PRR15L proline rich 15-like 0.00185369557 0.004837292973 6.0267 0.0687 0.0770 0.2332 0.0948 0.0455 0.27599755 TBKBP1 TBK1 binding protein 1 3.16724162E-12 1.05992379E-10 6.0116 1.7063 3.4388 1.4955 1.1395 3.1403 1.5127100287466 PNMA6D paraneoplastic Ma antigen family member 6D (pseudogene) 4.91133772E-07 2.74015154E-06 6.0024 0.3519 1.2629 0.6875 0.7513 0.7352 0.5872338707 B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 2.29139145E-06 1.10353992E-05 5.9898 0.2705 1.4284 0.9163 0.1892 1.2923 0.7674100169951 SNAR-A3 small ILF3/NF90-associated RNA A3 0.00316699782 0.007830498532 5.9801 0.0453 0.0718 0.1510 0.1339 0.0528 0.19518740 TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 3.54546979E-10 4.88190084E-09 5.9647 1.8617 2.6364 1.6305 1.0000 2.6134 1.4599677809 SNORA24 small nucleolar RNA, H/ACA box 24 9.26512945E-12 2.43937241E-10 5.9196 4.0578 4.3835 1.8934 2.7572 3.7866 1.3450677806 SNORA20 small nucleolar RNA, H/ACA box 20 6.88502043E-10 8.50020901E-09 5.9176 0.1270 0.6080 0.2044 0.2524 0.2153 0.2145574040 SNORA6 small nucleolar RNA, H/ACA box 6 9.52917894E-09 8.18303485E-08 5.9117 1.1786 4.5591 2.4412 1.1052 4.4426 0.9008677828 SNORA47 small nucleolar RNA, H/ACA box 47 5.72224515E-07 3.14777814E-06 5.9110 0.0605 0.2149 0.2470 0.1841 0.0672 0.1557100287898 TTC34 tetratricopeptide repeat domain 34 0.00044306399 0.001322760928 5.9055 0.2721 0.7807 0.4142 0.1329 0.2468 0.33263595 IL12RB2 interleukin 12 receptor, beta 2 2.21604794E-08 1.73560343E-07 5.8981 1.1388 1.6701 1.7257 0.8910 1.8421 1.80666004 RGS16 regulator of G-protein signaling 16 1.11626723E-06 5.75357826E-06 5.8966 0.9933 1.9676 1.2944 0.7531 2.0800 1.41723605 IL17A interleukin 17A 0.00705505954 0.015901079049 5.8941 0.1455 0.1496 0.3486 0.1363 0.0752 0.3500

374378 GALNT18 8.02144613E-06 3.44056018E-05 5.8783 1.1433 3.0322 1.3690 0.9305 1.2253 1.3416100500862 MIR3648 microRNA 3648 6.86911829E-10 8.4863103E-09 5.8698 0.3321 0.3321 0.3321 0.3970 0.3970 0.397095 ACY1 aminoacylase 1 6.85453081E-07 3.7044066E-06 5.8635 5.0328 3.0158 1.6592 7.5489 0.9256 1.571664978 MRPL38 mitochondrial ribosomal protein L38 2.14475423E-09 2.24965266E-08 5.8555 1.1732 1.2059 1.6697 0.8368 0.9644 1.47727185 TRAF1 TNF receptor-associated factor 1 9.73761074E-14 7.83813319E-12 5.8553 1.9564 2.0678 2.4489 1.3682 2.1639 1.99451474 CST6 cystatin E/M 0.00157454665 0.004187789874 5.8548 0.6336 0.9063 0.5088 0.2428 0.4232 0.479079173 C19orf57 chromosome 19 open reading frame 57 3.77507689E-07 2.17665525E-06 5.8416 0.1777 0.2332 0.3060 0.6426 0.1792 0.42266373 CXCL11 chemokine (C-X-C motif) ligand 11 0.00162310032 0.004302080397 5.8209 0.0835 0.0995 0.4275 0.2261 0.0822 0.2221

7965 AIMP2 3.85534507E-10 5.22302976E-09 5.8199 7.8663 3.1922 2.1492 2.5647 5.8931 0.94416624 FSCN1 fascin actin-bundling protein 1 9.66378851E-09 8.2744491E-08 5.7798 0.8314 0.9523 0.9073 0.5919 0.9506 0.7741259307 IL4I1 interleukin 4 induced 1 8.82063825E-07 4.64602774E-06 5.7786 0.5960 1.4519 1.4245 0.3920 0.9570 0.8265692149 SCARNA14 small Cajal body-specific RNA 14 2.05695723E-05 8.08621398E-05 5.7733 0.0657 0.0462 0.1673 0.2355 0.1183 0.2178284114 TMEM102 transmembrane protein 102 5.26893937E-12 1.59923688E-10 5.7718 1.1496 2.2756 1.5378 1.1504 3.0770 2.053151659 GINS2 GINS complex subunit 2 (Psf2 homolog) 7.70057337E-08 5.25999539E-07 5.7699 1.7905 2.1038 1.5366 1.0622 2.2413 1.3267677775 SCARNA5 small Cajal body-specific RNA 5 2.89411953E-10 4.12813052E-09 5.7669 0.1692 0.2993 0.1076 0.6715 0.0788 0.155365263 PYCRL pyrroline-5-carboxylate reductase-like 2.5853898E-11 5.59718512E-10 5.7668 1.2316 2.4589 1.7907 1.1180 3.3508 1.76576361 CCL17 chemokine (C-C motif) ligand 17 0.0067211759 0.015244454575 5.7616 0.0522 0.0449 0.3544 0.1260 0.0176 0.160626781 SNORA67 small nucleolar RNA, H/ACA box 67 5.73090043E-11 1.05347095E-09 5.7612 0.3790 3.3738 0.5775 0.3761 1.7078 0.4376677846 SNORA80 small nucleolar RNA, H/ACA box 80 4.85087572E-10 6.33108579E-09 5.7554 0.0594 0.2345 0.1224 0.2564 0.0427 0.22708331 HIST1H2AJ histone cluster 1, H2aj 5.20948312E-11 9.7229495E-10 5.7529 0.4342 2.6519 1.9128 0.3182 9.4752 1.151929893 PSMC3IP PSMC3 interacting protein 6.77966384E-07 3.66937256E-06 5.7513 1.7105 3.5226 2.3077 1.2876 4.5286 3.14777371 UCK2 uridine-cytidine kinase 2 3.78946877E-11 7.51804271E-10 5.7476 0.4033 0.0444 0.2390 0.1983 0.7060 0.89707980 TFPI2 tissue factor pathway inhibitor 2 0.00184969409 0.004828919906 5.7357 0.4204 0.7643 0.8639 0.8560 0.4738 0.7729389857 CENPVP1 hypothetical protein 0.00414260784 0.009958391065 5.7342 0.5923 0.7913 0.9569 0.3894 0.8309 0.839856915 EXOSC5 exosome component 5 1.08573728E-11 2.76975904E-10 5.7204 11.0154 3.5451 1.6465 4.3056 1.4247 0.755511001 SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 3.57795732E-10 4.91552152E-09 5.7141 0.5165 1.5791 1.0695 0.4435 1.2586 1.216980072 HEXA-AS1 HEXA antisense RNA 1 8.86286416E-05 0.000308226597 5.7122 0.6614 0.9506 15.7484 0.9434 0.4618 10.1542797 CALCB calcitonin-related polypeptide beta 0.00235430881 0.006004595079 5.7113 2.0405 1.8411 2.0712 1.1593 1.6070 1.85008326 FZD9 frizzled class receptor 9 7.35596584E-08 5.04535315E-07 5.7008 0.9534 1.5832 0.9196 0.8121 1.8467 0.84339837 GINS1 GINS complex subunit 1 (Psf1 homolog) 3.87856051E-07 2.22788612E-06 5.6962 1.5298 2.6709 1.8742 1.1909 2.7398 2.1720

4791 NFKB2 1.52829157E-15 5.36233287E-13 5.6934 1.8644 2.0668 2.4955 2.1317 3.2974 3.331584790 TUBA1C tubulin, alpha 1c 4.03901881E-11 7.90160082E-10 5.6906 1.0455 1.0952 1.2470 0.8578 1.6617 1.699630846 EHD2 EH-domain containing 2 0.00153304681 0.004088721548 5.6774 0.1119 0.1687 0.8440 0.1443 0.4174 0.4742147841 SPC24 SPC24, NDC80 kinetochore complex component 9.66337538E-07 5.04195303E-06 5.6646 1.3122 2.1774 2.2729 0.9397 2.6512 2.384279586 CHPF chondroitin polymerizing factor 5.86914319E-15 1.24698819E-12 5.6630 0.8149 1.6264 2.2411 0.4234 0.6215 1.16671435 CSF1 colony stimulating factor 1 (macrophage) 3.5013153E-11 7.06460357E-10 5.6627 1.0678 1.7684 1.5452 0.9796 1.4888 1.8636389257 LRRC14B leucine rich repeat containing 14B 0.00748560112 0.016753662862 5.6558 1.2839 0.4546 0.9556 0.8335 0.3422 0.4759220001 VWCE von Willebrand factor C and EGF domains 4.52397012E-06 2.04292438E-05 5.6529 1.5422 2.9410 1.2078 1.1263 3.8712 1.546883903 GSG2 germ cell associated 2 (haspin) 3.41475749E-06 1.58522482E-05 5.6486 4.4987 4.2339 1.5964 0.3473 4.3028 1.4979348938 NIPAL4 ichthyin protein 5.87222691E-07 3.22407843E-06 5.6479 0.4690 1.2731 1.2889 0.3302 1.4137 0.829989891 WDR34 WD repeat domain 34 1.07420215E-08 9.09959277E-08 5.6410 0.8617 1.1568 0.8262 0.8460 0.6374 0.9192131405 TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase 0.00892640995 0.019563795434 5.6336 0.7248 1.1033 2.5326 0.4921 1.6867 1.803427033 ZBTB32 zinc finger and BTB domain containing 32 6.85151888E-09 6.16704201E-08 5.6303 0.8331 1.9558 2.6583 0.3027 1.1603 2.609289944 GLB1L2 galactosidase, beta 1-like 2 6.19687858E-08 4.32999485E-07 5.6196 0.7517 0.8124 0.8322 0.6306 0.6318 0.68447301 TYRO3 TYRO3 protein tyrosine kinase 1.14819117E-05 4.7573127E-05 5.6190 1.3783 2.3320 1.4339 0.7265 1.6603 0.824492312 MEX3A mex-3 RNA binding family member A 8.62213017E-06 3.67320034E-05 5.6142 0.3496 0.6040 0.9487 0.2632 0.2014 0.3671619505 SNORA21 small nucleolar RNA, H/ACA box 21 7.25992812E-10 8.90889232E-09 5.6131 2.8722 3.5237 2.7575 1.3091 3.2439 1.86603276 PRMT1 protein arginine methyltransferase 1 1.23307596E-13 9.31023305E-12 5.6117 1.1060 1.3675 1.1245 0.9208 2.0309 1.315622824 HSPA4L heat shock 70kDa protein 4-like 0.00238005477 0.006062918382 5.6084 1.3037 1.4694 1.3048 0.9655 0.8047 1.338727132 CPNE7 copine VII 3.4354572E-05 0.000129135309 5.5969 1.1809 2.9848 3.0031 1.0848 2.0413 2.4583260429 PRSS33 protease, serine, 33 0.00535940818 0.012493889551 5.5943 0.7652 2.1017 0.8779 0.3530 0.8005 0.71215738 PTGFRN prostaglandin F2 receptor inhibitor 1.40119621E-06 7.07255722E-06 5.5940 1.8052 0.8986 1.4133 1.5654 1.3846 1.785956 ACRV1 acrosomal vesicle protein 1 0.00797364979 0.017724395253 5.5903 0.0678 0.0541 0.0962 0.2485 0.0327 0.200410514 MYBBP1A MYB binding protein (P160) 1a 1.25193855E-12 5.12825503E-11 5.5854 0.5895 0.6346 0.6767 0.5798 0.8718 0.796060681 FKBP10 FK506 binding protein 10, 65 kDa 0.00170718963 0.00449643118 5.5820 0.0421 0.0372 0.3291 0.0662 0.0902 0.12849618 TRAF4 TNF receptor-associated factor 4 4.02664846E-10 5.41390144E-09 5.5816 1.3876 2.5840 1.8266 0.9909 2.4230 2.90582247 FGF2 fibroblast growth factor 2 (basic) 0.00298672129 0.007437090687 5.5778 1.3518 1.0668 1.4140 1.4039 1.1076 1.4306375387 NRROS negative regulator of reactive oxygen species 7.29566817E-13 3.426901E-11 5.5767 2.0377 2.0073 2.4321 1.4887 2.5077 2.21991154 CISH cytokine inducible SH2-containing protein 8.45289985E-09 7.344336E-08 5.5763 1.2316 2.1272 0.8795 2.0906 2.5380 1.659123466 CBX6 chromobox homolog 6 3.04215498E-16 2.05875022E-13 5.5697 2.8046 2.1028 1.7779 2.4390 3.4299 2.84578728 ADAM19 ADAM metallopeptidase domain 19 1.87302397E-07 1.16487046E-06 5.5683 0.4285 0.7136 1.1243 0.5010 0.9260 1.466979714 CCDC51 coiled-coil domain containing 51 7.61192528E-13 3.54808925E-11 5.5667 0.5104 1.7573 1.3450 0.1273 1.2798 0.9969

solute carrier family 7 (amino acid transporter light chain, L system), member 5

ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

3898 LAD1 ladinin 1 3.12791244E-05 0.000118378658 5.5564 0.2522 1.6799 0.3620 0.0524 0.5267 0.2829

23415 KCNH4 3.5296555E-06 1.63358321E-05 5.5315 0.7014 1.7717 1.2863 0.5059 1.6348 0.88033562 IL3 interleukin 3 (colony-stimulating factor, multiple) 0.00710011054 0.015994725654 5.5246 0.1173 0.0393 0.2797 0.3432 0.0405 0.2769339456 TMEM52 transmembrane protein 52 6.8464926E-05 0.000243336146 5.5116 0.7485 0.9979 1.0213 0.4532 0.5256 1.251284517 ACTRT3 actin related protein M1 1.85813188E-05 7.37120837E-05 5.5111 2.1476 2.5722 1.2144 1.5290 3.0839 2.179430850 CDR2L cerebellar degeneration-related protein 2-like 2.16265712E-05 8.45987388E-05 5.5009 1.7556 2.8303 1.4234 1.4573 1.5537 1.1346151230 KLHL23 kelch-like family member 23 0.00760793626 0.01699656438 5.4991 0.8731 1.7426 1.1380 0.5608 1.6489 1.108257761 TRIB3 tribbles homolog 3 (Drosophila) 2.66735969E-09 2.72583872E-08 5.4925 0.8203 1.0994 1.7152 0.9773 1.2248 2.530584649 DGAT2 diacylglycerol O-acyltransferase 2 3.07455117E-09 3.08671423E-08 5.4757 0.1136 0.3952 1.9797 0.1991 0.2872 0.1188100287177 LOC100287177 uncharacterized LOC100287177 3.00546956E-08 2.25712864E-07 5.4748 1.2713 1.3968 2.3846 0.9638 1.3517 2.438964106 NPFFR1 neuropeptide FF receptor 1 0.00902966823 0.019768526567 5.4748 0.2902 0.2356 0.4518 0.3231 0.0657 0.316127198 HCAR1 hydroxycarboxylic acid receptor 1 0.00207770435 0.005369704926 5.4675 0.9658 1.7569 1.8269 0.4505 0.6853 1.3791171177 RHOV ras homolog family member V 0.00027620492 0.000864502502 5.4610 1.8455 1.5283 1.0591 0.9587 0.9565 0.7538169522 KCNV2 potassium channel, subfamily V, member 2 0.00015734485 0.000517459527 5.4466 0.0931 0.2101 0.1516 0.0919 0.3125 0.176084798 C19orf48 chromosome 19 open reading frame 48 2.03572125E-12 7.52969608E-11 5.4442 2.2793 2.9717 1.5460 2.0058 4.0423 2.268123246 BOP1 block of proliferation 1 8.8503697E-13 3.93821332E-11 5.4337 2.7472 8.6311 3.4115 0.7466 5.9017 2.102689858 SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene) 0.00154281865 0.004111782724 5.4319 0.1781 0.7024 1.1785 0.1808 0.4583 0.70381113 CHGA chromogranin A (parathyroid secretory protein 1) 0.00227619631 0.005821760768 5.4283 0.1086 0.1670 0.3636 0.1869 0.0702 0.37405888 RAD51 RAD51 recombinase 3.52152592E-07 2.0440064E-06 5.4224 1.4516 0.3482 10.6911 1.1945 0.5244 7.2320100507600 LOC100507600 uncharacterized LOC100507600 0.00011187574 0.000380456634 5.4214 1.0209 1.2569 2.6075 0.5269 0.6674 1.30683485 IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0006291921 0.001818794198 5.4176 0.8503 0.6631 1.5769 0.6136 0.4478 1.39037866 IFRD2 interferon-related developmental regulator 2 3.68802083E-12 1.20334851E-10 5.4095 2.1549 1.1868 2.0755 1.3279 1.2819 2.2158646862 LOC646862 uncharacterized LOC646862 0.0093237397 0.020337038533 5.4067 0.5647 0.5002 0.5379 0.2019 0.3950 0.4087181 AGRP agouti related protein homolog (mouse) 0.00229402774 0.005864904836 5.4023 0.6678 1.1005 0.8206 0.5369 0.5812 0.614454478 FAM64A family with sequence similarity 64, member A 8.61121987E-07 4.55146686E-06 5.3989 1.5110 1.8745 2.2947 0.9133 1.1920 2.11193394 IRF8 interferon regulatory factor 8 0.00018566233 0.000600960515 5.3940 1.7690 2.5334 2.2189 1.2728 3.0060 1.93414173 MCM4 minichromosome maintenance complex component 4 1.05798469E-08 8.97053194E-08 5.3851 4.3417 0.3189 0.3031 4.7177 1.0515 3.141611018 TMED1 transmembrane emp24 protein transport domain containing 1 5.13911171E-07 2.85589566E-06 5.3807 1.3527 1.1828 1.3253 1.2151 1.9411 1.5403677821 SNORA39 small nucleolar RNA, H/ACA box 39 7.86808051E-06 3.38271923E-05 5.3802 0.3606 0.2706 0.8950 0.3304 0.5235 0.485910607 TBL3 transducin (beta)-like 3 1.29250117E-15 4.92012112E-13 5.3792 0.5410 0.7103 0.9031 0.6897 0.7462 1.07142355 FOSL2 FOS-like antigen 2 6.29228441E-10 7.912775E-09 5.3749 1.8229 2.3417 1.9902 1.5872 3.8442 2.77242865 FFAR3 free fatty acid receptor 3 4.51690272E-05 0.000166102822 5.3720 0.7722 1.4411 1.3595 0.5468 0.5004 0.7812222229 LRWD1 hypothetical protein DKFZp434K1815 4.13948926E-14 4.55643059E-12 5.3631 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706690 SPINK1 serine peptidase inhibitor, Kazal type 1 0.00738327426 0.016540851802 5.3624 0.0820 0.0524 0.0810 0.0699 0.0317 0.145792745 SLC38A5 solute carrier family 38, member 5 3.7001597E-11 7.37303274E-10 5.3587 0.8252 1.6500 1.8663 0.7378 2.5584 1.09416573 SLC19A1 solute carrier family 19 (folate transporter), member 1 2.18149518E-11 4.88483823E-10 5.3555 0.4500 1.1687 0.7462 0.3478 1.0064 0.6461164312 LRRN4 leucine rich repeat neuronal 4 0.00454131809 0.010808136331 5.3456 0.0717 0.1726 0.2214 0.2721 0.7251 0.2684768 CA9 carbonic anhydrase IX 0.00164848228 0.004360948047 5.3438 0.1217 0.1653 0.3879 0.1132 0.3135 0.37314000 LMNA lamin A/C 2.79163004E-07 1.66097897E-06 5.3398 0.8804 1.3136 1.1284 0.4210 1.4607 0.7811284948 SH2D6 SH2 domain containing 6 0.00512541087 0.012031283066 5.3353 0.3977 0.9326 0.7504 0.3887 0.6502 0.6326125111 GJD3 gap junction protein, delta 3, 31.9kDa 4.87965429E-05 0.000178305053 5.3296 0.2546 1.0807 0.9562 0.2004 0.5956 0.70865213 PFKM phosphofructokinase, muscle 3.28229932E-13 1.96636633E-11 5.3289 0.7581 1.4261 1.1502 0.6820 1.2176 0.6864400745 SH2D5 SH2 domain containing 5 8.20229182E-05 0.000287497173 5.3207 3.3018 2.6015 2.1458 2.0564 1.9948 1.9149283888 IL21R-AS1 hypothetical protein LOC283888 5.78789758E-06 2.56068922E-05 5.3110 0.1867 0.2095 0.2606 0.3006 0.0988 0.36312155 F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.01092511042 0.023331418609 5.3086 0.0534 0.0352 0.1929 0.1912 0.0347 0.1751285613 RELL2 RELT-like 2 9.63316605E-10 1.13486273E-08 5.3075 1.0934 2.2353 2.7676 0.8548 4.6032 3.876279413 ZBED2 zinc finger, BED-type containing 2 5.27917096E-07 2.92749657E-06 5.3021 0.1986 1.8352 2.4690 0.4125 1.5726 3.373955092 TMEM51 transmembrane protein 51 0.02006303405 0.039559558289 5.2990 1.4857 0.9313 1.2306 0.6167 0.4303 0.92219156 EXO1 exonuclease 1 4.24600111E-06 1.92752627E-05 5.2986 1.2637 1.7208 2.3462 1.4017 1.9327 2.80385424 POLD1 polymerase (DNA directed), delta 1, catalytic subunit 1.94740891E-11 4.4646243E-10 5.2919 1.0017 0.8529 1.3898 0.6484 0.9779 1.4557

56052 ALG1 2.08072036E-11 4.70531218E-10 5.2819 1.0117 1.3544 0.9755 0.7405 1.2353 1.01824174 MCM5 minichromosome maintenance complex component 5 2.95284115E-10 4.17926519E-09 5.2795 0.6279 0.7219 0.9925 0.6703 1.0122 1.00432264 FGFR4 fibroblast growth factor receptor 4 3.14768669E-06 1.47020785E-05 5.2747 0.3757 0.4912 0.5094 0.4826 0.3702 0.4562

9136 RRP9 4.59707904E-11 8.78638371E-10 5.2735 2.9831 4.6736 1.3442 1.3122 4.3046 0.81483037 HAS2 hyaluronan synthase 2 0.01046755228 0.022483027541 5.2616 0.4947 0.8029 0.9963 0.4266 0.2153 0.9041161394 SAMD15 sterile alpha motif domain containing 15 0.01180008439 0.024972335177 5.2607 0.2441 0.1938 0.2779 0.5046 0.2926 0.53276660 SOX5 SRY (sex determining region Y)-box 5 0.00992733531 0.021491975213 5.2603 0.7843 0.9404 0.5851 0.6147 0.5729 0.42925731 PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 0.00044311622 0.001322760928 5.2470 0.1661 0.8470 1.5138 0.2155 0.2646 0.9119283600 SLC25A47 chromosome 14 open reading frame 68 0.01577562055 0.032117229931 5.2421 0.0823 0.0558 0.0941 0.3422 0.0353 0.18777015 TERT telomerase reverse transcriptase 8.80260977E-08 5.91545736E-07 5.2359 0.6808 1.3719 0.6070 0.4112 1.5738 0.582184267 C9orf64 chromosome 9 open reading frame 64 6.33314128E-11 1.13673043E-09 5.2329 1.5686 1.6227 2.0882 1.4746 2.1458 2.61731718 DHCR24 24-dehydrocholesterol reductase 4.08622584E-10 5.47788103E-09 5.2199 0.4866 0.8404 0.7602 0.4866 0.8425 0.801110205 MPZL2 myelin protein zero-like 2 7.37005702E-06 3.18659919E-05 5.2144 1.2672 2.0640 1.8067 1.0418 1.3824 1.37517453 WARS tryptophanyl-tRNA synthetase 2.43372942E-11 5.33202685E-10 5.2135 0.6552 2.3166 2.7651 0.2574 3.7401 3.7100284069 FAM171A2 Similar to hypothetical gene supported by AL050367; AK022946 3.8326989E-05 0.000143154281 5.2128 1.1381 0.8035 1.0789 1.0414 0.7241 0.87098572 PDLIM4 PDZ and LIM domain 4 0.01003903878 0.02170808481 5.2124 0.1669 0.3601 0.3878 0.2510 0.2145 0.42457298 TYMS thymidylate synthetase 7.72944459E-08 5.27380177E-07 5.2105 1.0792 1.8348 2.3029 0.7307 2.9956 1.35192161 F12 coagulation factor XII (Hageman factor) 8.32116578E-09 7.25402391E-08 5.2096 0.2302 0.4892 0.3945 0.1880 0.1907 0.19177703 PCGF2 polycomb group ring finger 2 0.00256830864 0.006497042164 5.2091 1.8096 3.6321 2.0260 1.2072 3.6250 1.546779946 C10orf95 chromosome 10 open reading frame 95 1.28943483E-06 6.55917406E-06 5.2091 1.3005 2.2380 2.0210 0.9001 2.0988 1.886055165 CEP55 centrosomal protein 55kDa 8.49605455E-07 4.49449649E-06 5.2087 2.9459 2.2393 2.4705 2.9260 1.5595 2.812610963 STIP1 stress-induced phosphoprotein 1 1.63216481E-14 2.43701519E-12 5.2012 1.8012 2.7928 1.7959 1.5479 4.3256 2.46052023 ENO1 enolase 1, (alpha) 3.65078193E-14 4.1954143E-12 5.1996 0.3639 2.3663 1.5065 0.2322 2.2055 0.927157491 AHRR aryl-hydrocarbon receptor repressor 6.95196689E-07 3.75262449E-06 5.1989 0.2042 0.3424 0.4836 0.1648 0.3567 0.4595147906 DACT3 dishevelled-binding antagonist of beta-catenin 3 2.10466766E-07 1.29352464E-06 5.1923 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970100126798 SNAR-A1 small ILF3/NF90-associated RNA A1 0.00385719078 0.009331204821 5.1882 0.0355 0.0368 0.1533 0.1176 0.0500 0.149154919 HEATR2 HEAT repeat containing 2 9.05961738E-14 7.40214508E-12 5.1734 0.7527 1.0506 0.9339 0.4492 0.8590 0.7931

442459 XRCC6P5 9.33582356E-07 4.89200367E-06 5.1679 0.1076 0.0110 0.1576 0.0154 0.0137 0.1504147645 VSIG10L V-set and immunoglobulin domain containing 10 like 1.80408486E-06 8.90925366E-06 5.1641 0.7340 1.1567 1.3611 0.5850 1.1625 1.59142250 FGF5 fibroblast growth factor 5 0.00016656237 0.000544636297 5.1634 1.0928 0.9290 1.1444 0.9780 0.5156 0.7392407007 MIR222 microRNA 222 0.00806724779 0.017906310925 5.1461 0.1400 0.1014 0.2284 0.4005 0.0281 0.371926509 MYOF myoferlin 0.00028346228 0.000885096084 5.1447 0.9761 0.6465 1.5066 1.0686 0.4743 1.0799705 BYSL bystin-like 3.19056833E-10 4.45703857E-09 5.1395 6.4097 4.8248 0.8911 2.6519 2.8460 1.21251104 RCC1 regulator of chromosome condensation 1 1.10154301E-13 8.50641606E-12 5.1273 0.5950 0.7853 0.8956 0.5614 0.8893 0.905784258 SYT3 synaptotagmin III 0.00257626468 0.006513561401 5.1267 0.5058 0.2999 0.5642 0.4273 0.1312 0.37155719 PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 2.48731493E-15 6.78331617E-13 5.1262 0.3321 0.3321 0.3321 0.3970 0.3970 0.397064943 NT5DC2 5'-nucleotidase domain containing 2 1.17314014E-08 9.8328517E-08 5.1249 0.3086 0.8822 0.9014 0.3523 1.3839 0.858624147 FJX1 four jointed box 1 (Drosophila) 8.8947168E-07 4.68099842E-06 5.1191 0.7735 0.7394 1.1856 0.5205 0.5689 0.92649569 GTF2IRD1 GTF2I repeat domain containing 1 9.47736311E-09 8.1491943E-08 5.1115 1.3303 2.3484 0.9314 0.8462 0.9924 0.8471677842 SNORA76 small nucleolar RNA, H/ACA box 76 2.6522766E-07 1.5847743E-06 5.1083 3.5673 3.2393 2.0226 2.6022 2.3096 1.7416440829 SHISA8 shisa family member 8 0.00039528288 0.001195796165 5.1062 1.2458 1.2128 1.7171 0.9484 0.3846 1.068454345 SOX18 SRY (sex determining region Y)-box 18 0.00444501764 0.010601665881 5.1038 0.1484 0.3944 0.8617 0.0989 0.2478 0.9242255057 C19orf26 chromosome 19 open reading frame 26 0.00027540863 0.000862575666 5.1036 0.6860 2.7022 1.2854 0.1770 2.5618 1.17878437 RASAL1 RAS protein activator like 1 (GAP1 like) 5.06271767E-06 2.26674779E-05 5.0965 0.8401 1.8694 2.0019 0.5398 1.2397 1.3547701 BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.81299777E-09 1.9544009E-08 5.0927 0.5096 1.0650 0.7731 0.5211 1.2668 0.96948751 ADAM15 ADAM metallopeptidase domain 15 1.63350202E-12 6.28738303E-11 5.0857 0.4238 0.4998 1.6388 0.3798 0.6273 0.80807083 TK1 thymidine kinase 1, soluble 1.2942754E-07 8.3241817E-07 5.0690 2.1938 0.6689 1.0042 6.0989 0.3801 1.2556677799 SNORA11 small nucleolar RNA, H/ACA box 11 5.98992176E-06 2.63793325E-05 5.0683 0.0698 0.2966 0.2118 0.2012 0.1030 0.139463875 MRPL17 mitochondrial ribosomal protein L17 1.08657606E-10 1.78062043E-09 5.0515 2.1591 2.0910 1.9459 2.4600 4.3346 2.61931026 CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.60520462E-06 8.01374284E-06 5.0509 0.7137 1.5540 1.3252 0.3638 1.6147 1.09003714 JAG2 jagged 2 1.63753587E-07 1.03247258E-06 5.0496 0.4960 0.5447 0.6484 0.1500 0.4581 0.639623170 TTLL12 tubulin tyrosine ligase-like family, member 12 4.37553789E-12 1.37927834E-10 5.0445 0.9980 1.8354 1.1845 0.6582 2.4220 1.4029283643 C14orf80 chromosome 14 open reading frame 80 8.8190432E-11 1.49343427E-09 5.0357 1.2296 2.0737 1.8163 0.8565 1.8645 1.8025246754 MTVR2 Mouse Mammary Tumor Virus Receptor homolog 2 0.00781534789 0.017406391589 5.0328 0.0352 0.0654 0.0964 0.0816 0.0023 0.1850100131496 LOC100131496 uncharacterized LOC100131496 0.00468404549 0.011106381723 5.0320 1.6524 3.4572 1.9331 0.4923 1.4283 0.7732441478 NRARP NOTCH-regulated ankyrin repeat protein 3.87316458E-05 0.000144547515 5.0319 1.1125 2.9209 1.3760 1.1370 3.5772 1.4153157983 C9orf66 chromosome 9 open reading frame 66 0.0004705692 0.001396725211 5.0312 0.1439 0.1606 0.4752 0.2476 0.2865 0.352725973 PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 5.39395775E-08 3.81188827E-07 5.0282 2.7215 4.9648 1.3320 2.0987 5.5016 1.620184951 TNS4 tensin 4 1.36626996E-05 5.57865582E-05 5.0277 0.5685 0.7130 1.3923 0.2383 0.2075 0.734223481 PES1 pescadillo ribosomal biogenesis factor 1 6.09125921E-14 5.64972022E-12 5.0257 1.4665 1.5589 1.8470 1.4577 3.2153 1.501829114 TAGLN3 transgelin 3 0.00377467247 0.009160687404 5.0204 1.4623 1.9449 1.2799 1.2486 1.5360 0.85501959 EGR2 early growth response 2 2.45962795E-07 1.48177784E-06 5.0203 1.7840 1.8361 1.4290 1.1548 2.7689 1.96909894 TELO2 telomere maintenance 2 1.4124108E-11 3.42730016E-10 5.0162 1.9685 1.8426 2.1693 1.3430 1.4401 1.96798828 NRP2 neuropilin 2 0.00019335828 0.00062355145 5.0042 0.6523 1.0710 1.5808 0.6038 0.5385 1.41043642 INSM1 insulinoma-associated 1 0.00064591305 0.001860359914 5.0038 0.1734 0.6641 1.2720 0.3117 0.6018 1.22353671 ISLR immunoglobulin superfamily containing leucine-rich repeat 0.01926549276 0.038208952974 5.0027 0.0147 0.0453 0.1371 0.1694 0.0126 0.258027301 APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 4.09473557E-14 4.53448536E-12 4.9986 4.2042 1.9497 3.1804 5.1300 2.8691 3.52745154 PDGFA platelet-derived growth factor alpha polypeptide 2.17480266E-05 8.50556383E-05 4.9905 0.2475 4.1130 0.9818 0.3356 2.2853 1.22275223 PGAM1 phosphoglycerate mutase 1 (brain) 8.59080225E-12 2.3016296E-10 4.9878 1.5755 2.5535 2.4402 1.1824 3.1096 2.768779094 CHAC1 ChaC, cation transport regulator homolog 1 (E. coli) 0.00012197399 0.000411580555 4.9830 1.2945 1.9221 2.5647 0.7189 2.3415 3.490253831 GPR84 G protein-coupled receptor 84 0.00337744742 0.008286923488 4.9801 1.1409 1.1271 1.7055 0.7039 0.4213 0.6502

84807 NFKBID 4.48884845E-13 2.45569578E-11 4.9795 1.4905 2.6105 1.5872 1.5624 2.8452 1.920185495 RPPH1 ribonuclease P RNA component H1 4.86222435E-11 9.20648325E-10 4.9768 4.4829 3.7166 2.7055 2.6891 8.4602 1.444751491 NOP16 NOP16 nucleolar protein 2.44517407E-10 3.56001758E-09 4.9748 0.3882 3.8228 0.4449 0.4296 5.8291 0.109364748 LPPR2 lipid phosphate phosphatase-related protein type 2 2.76484512E-08 2.10459751E-07 4.9741 0.4809 0.5932 0.4206 0.3672 0.3529 0.348323513 SCRIB scribbled planar cell polarity protein 2.95956451E-16 2.05875022E-13 4.9721 0.6960 1.5140 1.0555 0.5144 1.4573 0.9057100130015 URAHP urate (hydroxyiso-) hydrolase, pseudogene 0.01377412211 0.028548180491 4.9485 0.2865 0.5176 0.8051 0.2630 0.3119 0.4810677773 SCARNA23 small Cajal body-specific RNA 23 0.00101072374 0.002803695805 4.9428 0.1261 0.0275 0.0660 0.3529 0.0691 0.44003290 HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.01567686022 0.031937531128 4.9375 0.9495 0.9708 1.1799 0.5401 0.3783 0.594029886 SNX8 sorting nexin 8 1.41211912E-11 3.42730016E-10 4.9350 1.2272 1.4769 1.6409 0.7930 1.8977 2.02544345 CD200 CD200 molecule 2.11570956E-08 1.66486843E-07 4.9330 2.3916 1.6532 1.8147 2.0445 1.9943 2.3361200312 RNF215 ring finger protein 215 2.76074264E-07 1.64313646E-06 4.9329 0.4824 0.8751 1.6200 0.3582 0.5314 1.17472696 GIPR gastric inhibitory polypeptide receptor 0.00218992079 0.005624716426 4.9318 1.8941 1.9473 2.2691 1.1662 1.0737 2.4712

7517 XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 2.77884579E-11 5.93166709E-10 4.9287 0.8701 2.1433 2.6985 0.7425 2.1485 2.067881567 TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 1.92383557E-05 7.60708147E-05 4.9029 1.6924 3.9656 1.8915 1.0951 3.7410 1.719251154 MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 3.52558277E-09 3.48213234E-08 4.8992 1.9272 1.2443 5.5716 1.0982 2.3691 3.8817116835 HSPA12B heat shock 70kD protein 12B 0.00174541263 0.004586163297 4.8986 0.0897 0.0983 0.1604 0.2612 0.0893 0.17842175 FANCA Fanconi anemia, complementation group A 2.08203496E-09 2.19141375E-08 4.8980 1.2729 0.8296 1.3723 1.2486 0.9704 1.4417

potassium voltage-gated channel, subfamily H (eag-related), member 4

asparagine-linked glycosylation 1 homolog (S. cerevisiae, beta-1,4-mannosyltransferase)

ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)

X-ray repair complementing defective repair in Chinese hamster cells 6 pseudogene 5

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta

54814 QPCTL glutaminyl-peptide cyclotransferase-like 1.76710302E-09 1.91282621E-08 4.8959 2.7835 3.9131 6.3375 2.9512 7.9480 8.204181831 NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 1.04225016E-07 6.8651748E-07 4.8946 0.5996 0.6873 0.8873 0.3650 0.7922 1.2038399833 SPRNP1 shadow of prion protein homolog (zebrafish) pseudogene 1 0.01478485664 0.030360631668 4.8944 0.1050 0.2358 0.3447 0.4383 0.1251 0.185491608 RASL10B RAS-like, family 10, member B 7.25490616E-05 0.000256703418 4.8919 1.7254 3.5398 1.2867 0.7878 2.1359 0.75398061 FOSL1 FOS-like antigen 1 2.30809059E-06 1.11099661E-05 4.8891 1.1778 1.3518 1.5181 0.8455 1.9951 1.555325987 TSKU tsukushi, small leucine rich proteoglycan 0.00762056727 0.017020291557 4.8881 1.1800 1.1858 1.4218 1.3260 0.6451 1.097750831 TAS2R3 taste receptor, type 2, member 3 0.01053511173 0.022606877448 4.8843 0.0659 0.1953 0.1998 0.2029 0.0342 0.1635348487 FAM131C family with sequence similarity 131, member C 0.0091723717 0.020054753579 4.8789 0.4884 1.8103 1.5029 0.2546 1.0319 0.69172584 GALK1 galactokinase 1 9.05460389E-11 1.52907322E-09 4.8727 0.8474 1.8278 1.3843 0.6594 2.9408 1.41177975 MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 1.13901384E-11 2.88255691E-10 4.8692 0.6935 0.6873 0.8389 0.4590 1.4911 0.715455502 HES6 hairy and enhancer of split 6 (Drosophila) 4.16782929E-07 2.36946412E-06 4.8671 1.3776 3.4806 1.8256 0.5410 2.3716 1.7832

790 CAD 8.3315467E-12 2.26202112E-10 4.8668 1.4911 1.3159 1.6714 1.0688 1.9566 1.75036044 SNORA62 small nucleolar RNA, H/ACA box 62 5.50004762E-08 3.87869047E-07 4.8665 0.9454 1.2996 0.7771 0.9340 0.5451 0.68695822 PWP2 PWP2 periodic tryptophan protein homolog (yeast) 8.91854676E-14 7.40214508E-12 4.8652 1.3250 1.3746 1.7207 1.1052 1.7066 2.177379763 ISOC2 isochorismatase domain containing 2 3.43947669E-11 6.95970299E-10 4.8647 1.3831 1.5886 2.5016 1.1930 1.6358 2.8050150368 FAM109B family with sequence similarity 109, member B 4.44858562E-08 3.22025433E-07 4.8595 1.1122 1.7304 2.0023 0.7179 0.6523 1.419584811 BUD13 BUD13 homolog (S. cerevisiae) 3.70989469E-12 1.20832791E-10 4.8555 2.0845 2.8411 1.6813 1.8500 4.0816 2.2379125058 TBC1D16 TBC1 domain family, member 16 1.41040758E-05 5.735804E-05 4.8529 0.8316 0.3698 0.9498 0.4694 0.4035 0.58042615 LRRC32 leucine rich repeat containing 32 6.13862729E-07 3.36024559E-06 4.8511 0.7312 0.8186 1.2420 0.7047 0.8378 0.91856890 TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.69922554E-15 5.5443302E-13 4.8484 0.5390 0.5222 0.5890 0.5695 0.7124 0.6879731424 LOC731424 uncharacterized LOC731424 0.00254316976 0.006439126746 4.8389 0.0591 0.2063 0.2311 0.6067 0.0530 0.1772374659 HDDC3 HD domain containing 3 6.54376468E-10 8.17836308E-09 4.8280 1.3480 1.9464 1.5470 1.6528 2.4026 1.996954913 RPP25 ribonuclease P/MRP 25kDa subunit 6.08274214E-13 3.02021371E-11 4.8265 1.3512 2.5347 2.1858 1.0255 1.9670 1.84243565 IL4 interleukin 4 0.00326002337 0.008035498049 4.8168 0.1053 0.2060 0.9586 0.1456 0.0539 0.4138161424 NOP9 NOP9 nucleolar protein 1.78787067E-13 1.24259863E-11 4.8133 3.6782 3.6748 0.7258 0.4696 9.2325 0.66519401 RECQL4 RecQ protein-like 4 5.33013846E-07 2.94770853E-06 4.8036 0.1726 4.0763 2.2272 0.6561 3.7653 2.03264145 MATK megakaryocyte-associated tyrosine kinase 9.65972949E-09 8.2744491E-08 4.7905 0.7419 1.6178 1.5027 0.5650 1.5031 1.298310471 PFDN6 prefoldin subunit 6 7.80231966E-12 2.15353451E-10 4.7874 2.9677 1.9564 0.6790 2.1975 1.2935 0.428580381 CD276 CD276 molecule 0.00254822864 0.006450711235 4.7831 0.9331 1.2237 0.9134 0.5810 1.0177 0.849029925 GMPPB GDP-mannose pyrophosphorylase B 3.8788064E-11 7.66200547E-10 4.7807 1.7539 3.2363 1.4170 1.4010 2.9302 1.8815148304 C1orf74 chromosome 1 open reading frame 74 2.2963553E-07 1.39352388E-06 4.7788 1.9559 3.4121 1.8267 1.3422 2.7114 1.5528346689 KLRG2 killer cell lectin-like receptor subfamily G, member 2 0.00513095201 0.012041196396 4.7777 0.6000 1.1656 1.6566 0.4059 1.6344 1.5429219 ALDH1B1 aldehyde dehydrogenase 1 family, member B1 5.92018208E-13 2.99771164E-11 4.7726 1.6943 1.9060 1.7355 1.2327 2.4779 1.5409387597 ILDR2 chromosome 1 open reading frame 32 6.28311065E-06 2.75443853E-05 4.7720 0.2903 2.7617 4.5013 0.1386 0.4170 2.088710537 UBD ubiquitin D 0.00660546471 0.015015557509 4.7693 0.2900 0.2991 0.3232 0.3720 0.3466 0.369927349 MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 1.89897513E-08 1.51321734E-07 4.7675 1.2115 1.1532 1.2900 1.1585 1.6643 1.696923223 RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.61543671E-09 2.67877016E-08 4.7670 0.3892 0.4268 0.6024 0.4271 0.5513 0.669128989 NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 5.46219385E-14 5.33717679E-12 4.7662 1.9656 2.3192 2.0650 1.8818 2.9039 2.6244

63922 CHTF18 9.75397074E-09 8.34384613E-08 4.7643 0.3605 1.6201 1.1398 0.6592 1.1955 1.504723277 CLUH clustered mitochondria (cluA/CLU1) homolog 3.15102452E-11 6.51306787E-10 4.7617 0.5295 0.6920 0.7662 0.4580 1.0641 0.866190353 CTU1 ATP binding domain 3 7.41025679E-14 6.54107305E-12 4.7581 2.5074 2.8439 2.2504 2.2445 3.7008 2.379623203 PMPCA peptidase (mitochondrial processing) alpha 4.89867968E-10 6.38435628E-09 4.7577 1.5887 0.1956 0.5953 1.4740 0.6178 0.5039221527 ZBTB12 zinc finger and BTB domain containing 12 6.97513961E-06 3.03018904E-05 4.7525 0.6188 0.7730 0.5934 0.5694 0.6780 0.6476127703 C1orf216 hypothetical protein FLJ38984 5.53187728E-11 1.02409789E-09 4.7492 1.6366 1.3948 1.5161 1.1162 1.7439 1.687055210 ATAD3A ATPase family, AAA domain containing 3A 1.15931452E-11 2.92582802E-10 4.7441 1.7445 3.5172 1.8525 1.3938 5.2978 2.19892817 GPC1 glypican 1 3.97470625E-07 2.27382068E-06 4.7356 0.9700 4.4367 1.0777 0.6306 2.0238 1.1906342933 ZSCAN5B zinc finger and SCAN domain containing 5B 0.02237472712 0.043464917486 4.7348 0.0532 0.0193 0.2437 0.2172 0.0066 0.18118651 SOCS1 suppressor of cytokine signaling 1 1.13825556E-08 9.58884534E-08 4.7313 1.3577 1.8946 1.3808 1.2155 2.5718 2.22284605 MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 7.30267312E-07 3.92454245E-06 4.7280 1.2911 1.0269 1.5549 0.6504 0.6786 1.918279922 MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) 6.98918534E-09 6.25092485E-08 4.7278 2.2713 2.9173 2.2686 1.8094 4.3038 2.4115100129396 FAM106CP family with sequence similarity 106, member C pseudogene 0.01209584795 0.025494905263 4.7187 0.0728 0.0850 0.1735 0.2303 0.0331 0.12282936 GSR glutathione reductase 9.09766816E-16 4.17311256E-13 4.7169 1.0455 3.1132 1.9491 0.7888 3.1133 2.070310954 PDIA5 protein disulfide isomerase family A, member 5 5.91130829E-09 5.42755965E-08 4.7134 1.1379 1.6303 1.5340 0.9915 2.7997 1.94981233 CCR4 chemokine (C-C motif) receptor 4 1.67638462E-08 1.3517608E-07 4.7117 0.6563 2.7969 2.1147 0.3584 1.7812 1.229981620 CDT1 chromatin licensing and DNA replication factor 1 7.40544591E-08 5.0716757E-07 4.7107 1.4267 2.1966 2.4345 1.1185 2.3900 3.30757005 TEAD3 TEA domain family member 3 1.06017942E-06 5.49704833E-06 4.7093 0.6233 0.8584 0.7772 0.3824 1.0913 1.071916 AARS alanyl-tRNA synthetase 4.32004182E-13 2.39199406E-11 4.7089 3.4840 5.2038 1.7299 2.9682 3.9468 2.84017064 THOP1 thimet oligopeptidase 1 6.04829315E-12 1.77177105E-10 4.7054 0.5437 0.4080 0.7061 0.5140 0.6078 0.733455720 TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 3.60417621E-09 3.54824933E-08 4.7050 8.1945 0.6375 1.0108 17.6799 1.6620 4.7034100534611 TM4SF19-TCTEXTM4SF19-TCTEX1D2 readthrough 0.02627451538 0.049915569241 4.6986 0.3321 0.3321 0.3321 0.3970 0.3970 0.39709293 GPR52 G protein-coupled receptor 52 0.00751646674 0.016816564247 4.6973 0.0644 0.0525 0.1330 0.2430 0.1212 0.195627112 FAM155B family with sequence similarity 155, member B 0.00444948555 0.010608410436 4.6941 0.7167 0.4529 0.4823 0.6456 0.1889 0.4671

201232 SLC16A13 2.18440562E-07 1.334006E-06 4.6920 3.4660 2.8879 2.4999 2.5999 3.1898 2.71872167 FABP4 fatty acid binding protein 4, adipocyte 0.01451063888 0.029888219315 4.6911 0.0304 0.0768 0.0989 0.1621 0.1246 0.14962645 GCK glucokinase (hexokinase 4) 1.66907772E-08 1.34646305E-07 4.6908 0.0431 0.0300 0.1022 0.1486 0.0260 0.192457026 PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 2.04821159E-06 9.97731861E-06 4.6789 1.3428 1.6264 2.2422 0.9190 1.7865 1.9773

7516 XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 7.21979024E-06 3.12829043E-05 4.6789 1.3648 1.5679 1.4211 1.5951 1.8194 1.9259

112939 NACC1 8.99646684E-15 1.58061002E-12 4.6782 1.1865 3.2164 2.7884 1.2809 3.8964 2.7757192111 PGAM5 phosphoglycerate mutase family member 5 9.00475729E-14 7.40214508E-12 4.6779 7.8244 8.2349 1.9955 3.2464 9.1245 2.115355509 BATF3 Jun dimerization protein p21SNFT 0.0001121979 0.000381410222 4.6763 1.7471 2.1574 1.9495 1.2866 2.0742 2.439329923 HILPDA hypoxia inducible lipid droplet-associated 3.98340952E-06 1.81932214E-05 4.6697 2.2334 2.5691 1.8906 1.9922 3.7231 1.6747

4318 MMP9 0.01884475668 0.037493037355 4.6673 0.7207 0.6646 0.9814 0.3672 0.7442 0.462192092 ZC3HAV1L zinc finger CCCH-type, antiviral 1-like 0.00013203971 0.000441388519 4.6672 0.6365 1.1427 1.8096 0.4095 1.0700 2.174084002 B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 3.45627357E-08 2.55887483E-07 4.6671 1.0224 1.0358 1.2009 0.6759 0.8090 0.9967

84134 TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like 4.89417628E-10 6.3830399E-09 4.6664 1.2977 0.9999 1.7117 0.9804 1.4809 0.64382103 ESRRB estrogen-related receptor beta 0.01809364695 0.036177827578 4.6639 0.0479 0.0325 0.1322 0.0683 0.0293 0.146029015 SLC43A3 solute carrier family 43, member 3 9.1492233E-09 7.90423679E-08 4.6604 1.5464 1.9989 2.3485 1.0928 2.0617 2.043357513 CASKIN2 CASK interacting protein 2 0.0003219704 0.000994261128 4.6591 0.2480 0.4977 0.6884 0.1980 0.3587 0.542179187 FSD1 fibronectin type III and SPRY domain containing 1 2.45989877E-08 1.89891298E-07 4.6575 0.4374 0.7772 0.9642 0.3888 0.2282 0.66497268 TTC4 tetratricopeptide repeat domain 4 7.47388121E-07 4.00477295E-06 4.6558 2.2265 1.7689 2.0382 2.0772 2.1810 1.8924100287428 PNMA6C paraneoplastic Ma antigen family member 6C 1.02761332E-05 4.30932276E-05 4.6550 0.2654 1.6023 1.0655 0.5419 0.7692 0.7711100507423 MKNK1-AS1 MKNK1 antisense RNA 1 0.00871488141 0.019157641144 4.6531 0.0523 0.0304 0.1181 0.2602 0.0572 0.2008677845 SNORA79 small nucleolar RNA, H/ACA box 79 0.00491568481 0.0115910947 4.6510 0.2486 0.1079 0.1237 0.2538 0.2221 0.2464

6536 SLC6A9 9.21287405E-06 3.90212412E-05 4.6404 0.4705 0.8422 0.8995 0.4477 1.2728 1.33065228 PGF placental growth factor 0.00929677717 0.020292762218 4.6374 0.4046 2.2913 0.8253 0.2246 0.6457 0.901690874 ZNF697 zinc finger protein 697 0.00149634236 0.003999000663 4.6358 0.9965 1.5193 1.9390 0.7342 2.7327 1.6555

6507 SLC1A3 0.00170676795 0.004496260679 4.6342 0.8506 1.4329 1.0605 0.7739 1.0183 0.685354429 TAS2R5 taste receptor, type 2, member 5 0.0178090703 0.0357058991 4.6302 0.0370 0.0246 0.1946 0.1864 0.0115 0.14129047 SH2D2A SH2 domain containing 2A 1.25770191E-11 3.11814509E-10 4.6273 1.6156 2.5656 2.3882 0.9101 1.7965 1.4278124930 ANKRD13B ankyrin repeat domain 13B 1.08729088E-09 1.25839108E-08 4.6256 0.8357 2.0593 1.8715 0.3540 1.7726 1.422454512 EXOSC4 exosome component 4 7.52502953E-12 2.08962522E-10 4.6090 1.7256 3.0535 2.4751 1.3018 5.2860 2.7273205 AK4 adenylate kinase 4 3.77538379E-05 0.000141157791 4.6078 1.5260 1.4429 1.6300 1.0877 1.2390 2.008626086 GPSM1 G-protein signaling modulator 1 1.0328568E-07 6.80575531E-07 4.6016 0.2227 1.3835 0.4213 0.1826 2.6483 0.484579228 THOC6 THO complex 6 homolog (Drosophila) 5.99515289E-13 3.00238811E-11 4.5962 0.3560 0.7990 2.1820 0.1544 1.5898 1.24137023 TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 2.75535182E-11 5.89529139E-10 4.5946 1.1562 1.5524 1.2746 1.1293 2.0658 1.96351960 EGR3 early growth response 3 3.71993773E-06 1.71426739E-05 4.5903 2.7407 4.3386 2.3145 1.7359 3.5187 2.661079943 ZNF696 zinc finger protein 696 8.31192735E-10 1.00181752E-08 4.5901 1.9247 5.6647 2.0117 1.1379 4.6474 2.49563569 IL6 interleukin 6 (interferon, beta 2) 0.00270136459 0.006793192105 4.5895 1.5108 0.8470 0.7927 1.1150 0.5351 0.360310885 WDR3 WD repeat domain 3 7.03903584E-12 1.9909793E-10 4.5846 0.8264 4.2095 4.1514 0.7405 2.1603 3.54686319 SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.37687299E-09 1.54534541E-08 4.5807 1.7930 2.2544 1.9402 1.3528 2.4289 2.83629469 CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 2.79753669E-05 0.000107028037 4.5791 0.7246 2.4547 1.2843 0.5294 1.9024 1.077030844 EHD4 EH-domain containing 4 7.24168568E-11 1.27108627E-09 4.5771 2.2744 1.9901 1.2697 1.9891 2.0690 2.0456285368 PRRT3 proline-rich transmembrane protein 3 5.83802459E-09 5.36581415E-08 4.5699 1.4011 2.3348 1.6338 1.0561 2.1387 1.549523109 DDN dendrin 0.00066369478 0.001907365679 4.5675 0.5695 1.5875 2.1280 0.4852 1.4367 1.30202237 FEN1 flap structure-specific endonuclease 1 2.39496403E-08 1.85199756E-07 4.5606 0.7317 0.9243 1.4034 0.0732 2.6117 2.3777162073 ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 0.00114195915 0.003137725962 4.5592 0.2901 0.4680 1.6899 0.5640 0.2843 1.74527012 TERC telomerase RNA component 3.99293214E-09 3.88079022E-08 4.5583 1.4738 1.7604 1.1046 1.2508 1.6885 1.4475170487 ACTL10 chromosome 20 open reading frame 134 2.07636859E-06 1.00956378E-05 4.5559 0.8752 1.0850 1.3961 0.7242 0.9810 1.229390417 KNSTRN kinetochore-localized astrin/SPAG5 binding protein 2.64047229E-08 2.02038148E-07 4.5528 0.9622 0.7882 1.0002 0.8148 1.0169 1.19033321 IGSF3 immunoglobulin superfamily, member 3 0.00018970113 0.000612622656 4.5518 0.6193 0.8364 0.8910 0.5338 0.4826 0.62233696 ITGB8 integrin, beta 8 0.00242184529 0.006162366964 4.5444 0.8808 1.4480 2.4263 0.7672 1.1302 1.819554863 TOR4A torsin family 4, member A 3.04591427E-07 1.79474187E-06 4.5434 0.7080 2.1035 1.5101 0.4652 1.6390 1.574379803 HPS6 Hermansky-Pudlak syndrome 6 2.93876284E-15 7.51186751E-13 4.5427 1.4447 1.3490 1.9318 1.0467 1.9898 2.82999244 CRLF1 cytokine receptor-like factor 1 0.01875871638 0.037357958121 4.5394 0.2049 0.4005 0.3848 0.0969 0.1310 0.29464176 MCM7 minichromosome maintenance complex component 7 1.36848562E-09 1.53954057E-08 4.5379 2.1149 4.4993 1.5874 1.9315 4.2284 1.70692701 GJA4 gap junction protein, alpha 4, 37kDa 0.00794594775 0.017667115754 4.5373 0.7921 1.0618 0.6803 0.3333 0.6925 0.6068645367 GGT8P gamma-glutamyltransferase 8 pseudogene 0.01242609964 0.026106668113 4.5342 0.4415 0.0799 0.1502 0.3742 0.4486 0.192723539 SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 0.01892607635 0.037621547775 4.5326 0.2119 0.6634 0.5804 0.1417 0.3596 0.295183743 GRWD1 glutamate-rich WD repeat containing 1 1.78611648E-12 6.77093783E-11 4.5314 2.4972 3.6210 2.1899 1.8573 2.2667 2.19531111 CHEK1 checkpoint kinase 1 9.06302793E-09 7.84089234E-08 4.5314 1.6164 2.6155 1.7705 1.6970 2.8718 2.0902164091 PAQR7 progestin and adipoQ receptor family member VII 1.65785958E-06 8.24956705E-06 4.5312 0.1502 0.2289 0.2547 0.0972 0.1735 0.293851750 RTEL1 regulator of telomere elongation helicase 1 0.02322035439 0.044888099385 4.5266 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702288 FKBP4 FK506 binding protein 4, 59kDa 2.6412278E-11 5.70095652E-10 4.5255 2.0997 2.3886 1.9046 2.3566 2.3116 2.520610969 EBNA1BP2 EBNA1 binding protein 2 2.35340102E-11 5.1684307E-10 4.5214 0.4522 0.5152 0.6167 0.6851 0.1481 0.35264283 CXCL9 chemokine (C-X-C motif) ligand 9 0.00068216671 0.001954610344 4.5174 0.1254 0.0586 0.1019 0.1834 0.1585 0.136626233 FBXL6 F-box and leucine-rich repeat protein 6 1.33616154E-13 9.94277035E-12 4.5133 0.3106 2.0233 1.0418 0.3696 1.5018 0.82851981 EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.00474981E-13 7.98208198E-12 4.5131 0.6156 0.9614 1.2841 0.5772 0.8436 1.196925819 CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 9.59485007E-09 8.23471585E-08 4.5129 2.8816 2.0764 1.6216 2.0081 3.2285 1.53873099 HK2 hexokinase 2 6.45264048E-09 5.85415327E-08 4.5126 0.2827 0.5521 0.9317 0.3822 0.4156 0.6009253982 ASPHD1 aspartate beta-hydroxylase domain containing 1 0.00063216412 0.0018262297 4.5105 0.5901 1.3766 1.2836 0.2796 0.5435 0.8056118471 PRAP1 proline-rich acidic protein 1 0.00207588291 0.005366515637 4.5071 0.0708 0.1464 0.4011 0.1780 0.0412 1.1211115557 ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 3.75263786E-06 1.726289E-05 4.5014 1.0210 2.0112 1.1628 0.7312 1.4766 0.947523397 NCAPH non-SMC condensin I complex, subunit H 1.00805895E-08 8.59106955E-08 4.4994 1.5426 1.5524 2.3115 1.4902 1.4477 2.70427374 UNG uracil-DNA glycosylase 8.16350796E-11 1.39928347E-09 4.4937 1.9433 2.4005 1.4487 1.7778 2.9888 1.62782193 FARSA phenylalanyl-tRNA synthetase, alpha subunit 2.28733265E-14 3.02856103E-12 4.4922 2.4532 0.9227 1.9107 2.2805 1.8567 2.1861

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)

solute carrier family 16, member 13 (monocarboxylic acid transporter 13)

nucleus accumbens associated 1, BEN and BTB (POZ) domain containing

matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

solute carrier family 1 (glial high affinity glutamate transporter), member 3

1478 CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 7.7257202E-14 6.74791758E-12 4.4916 2.2506 1.5821 2.0435 2.9453 3.5794 2.939850636 ANO7 anoctamin 7 0.00023707623 0.000752058474 4.4880 0.0703 0.1130 0.1682 0.0228 0.0315 0.05406855 SYP synaptophysin 1.56767473E-06 7.83708689E-06 4.4845 1.5108 1.4000 1.7915 1.0281 0.7236 1.312327339 PRPF19 pre-mRNA processing factor 19 2.46620206E-14 3.14890479E-12 4.4832 1.7051 1.4259 2.1575 1.3121 2.8046 2.094510861 SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.22859841E-06 1.50377135E-05 4.4820 0.0191 0.0163 0.1155 0.1018 0.0148 0.1328401010 LOC401010 nucleolar complex associated 2 homolog (S. cerevisiae) pseudogene 4.20905482E-06 1.91217926E-05 4.4816 0.0137 0.2461 0.1345 0.2172 0.0495 0.26557475 WNT6 wingless-type MMTV integration site family, member 6 0.02197294127 0.042784482407 4.4786 0.5070 2.1501 0.5608 0.2354 0.6549 0.41939322 TRIP10 thyroid hormone receptor interactor 10 4.62176048E-10 6.08859463E-09 4.4741 1.8578 2.0849 2.2649 1.1956 1.8164 2.4180646471 LOC646471 uncharacterized LOC646471 3.3201407E-05 0.000125032174 4.4708 0.4482 0.2681 0.2525 0.4969 0.1161 0.28583833 KIFC1 kinesin family member C1 2.12439209E-07 1.30345508E-06 4.4682 0.7030 0.6512 0.9302 0.5834 0.5952 0.9729

1796 DOK1 5.92258046E-13 2.99771164E-11 4.4662 0.8836 1.7214 1.6243 0.7302 2.0393 1.74511825 DSC3 desmoglein 1 0.02610108399 0.04964803317 4.4642 0.7127 0.8782 0.3770 0.8636 0.6484 0.27945664 PSEN2 presenilin 2 4.70685209E-11 8.98206912E-10 4.4562 0.5549 0.8472 0.9250 0.4828 0.8054 0.75958568 RRP1 ribosomal RNA processing 1 7.87606148E-14 6.78827337E-12 4.4549 0.6133 1.3359 0.8421 0.6011 1.7983 1.01575971 RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.16755328E-14 2.97785966E-12 4.4523 1.1525 2.0767 1.4183 0.9120 1.9574 1.17619143 SYNGR3 synaptogyrin 3 4.26895524E-07 2.42393879E-06 4.4476 0.5768 0.4733 1.8868 0.3839 0.5294 1.8580441531 PGAM4 phosphoglycerate mutase family member 4 4.74264095E-11 9.0268266E-10 4.4462 0.3138 0.1600 0.2414 0.9611 0.0374 0.271384296 GINS4 GINS complex subunit 4 (Sld5 homolog) 1.38404891E-07 8.86723058E-07 4.4420 1.9401 2.2653 1.4889 1.5281 3.0119 1.910756675 NRIP3 nuclear receptor interacting protein 3 4.6030945E-05 0.000169026814 4.4410 2.1023 2.6884 2.1751 1.1130 1.2647 1.771010683 DLL3 delta-like 3 (Drosophila) 9.83290625E-06 4.13788261E-05 4.4398 0.7794 0.9622 1.2954 0.5557 1.1932 0.7473654320 SNORA8 small nucleolar RNA, H/ACA box 8 1.4498468E-07 9.24018165E-07 4.4374 0.0851 0.7588 0.2082 0.2589 0.2190 0.058365083 NOL6 nucleolar protein 6 (RNA-associated) 1.91075044E-12 7.1690415E-11 4.4339 0.8337 1.1041 1.2217 0.9712 1.4762 1.38868692 HYAL2 hyaluronoglucosaminidase 2 2.71286339E-13 1.69178976E-11 4.4339 0.5156 0.5092 0.8826 0.4432 0.4958 0.71441627 DBN1 drebrin 1 1.04984176E-08 8.91389803E-08 4.4329 0.2125 0.5363 0.6549 0.2328 0.5144 0.568410897 YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 5.83349653E-13 2.99409125E-11 4.4279 1.4617 3.0818 2.1406 1.2490 3.7871 2.080650832 TAS2R4 taste receptor, type 2, member 4 0.02488860415 0.047694239647 4.4239 0.1136 0.0228 0.2380 0.2329 0.1411 0.1480100379571 BACE1-AS BACE1 antisense RNA 0.00049445226 0.001462387769 4.4149 0.0786 0.2914 0.0627 0.1554 0.3321 0.04203329 HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.01321063E-09 1.18220847E-08 4.4116 4.1131 4.5312 1.4517 3.6304 10.5727 1.891211339 OIP5 Opa interacting protein 5 8.14705569E-06 3.48706961E-05 4.4095 0.3591 0.7963 1.2633 0.4399 0.6371 1.534779172 CENPO centromere protein O 3.77772497E-10 5.14356116E-09 4.4092 0.3853 3.8147 2.6008 0.8314 3.0928 2.208223761 PISD phosphatidylserine decarboxylase 4.6143454E-10 6.08760427E-09 4.4080 1.1334 2.4865 1.5642 1.0968 3.2245 1.54642649 NR6A1 nuclear receptor subfamily 6, group A, member 1 0.0029336511 0.007313913627 4.4071 1.8022 3.3254 2.4710 1.0061 3.2724 1.934284948 TIGD5 tigger transposable element derived 5 1.14694769E-11 2.89862078E-10 4.4031 0.7435 3.4120 0.8361 0.6878 2.2346 1.093460598 KCNK15 potassium channel, subfamily K, member 15 2.98435295E-05 0.000113391759 4.4030 1.6142 0.6563 1.0314 1.0949 0.8290 1.0355221416 C6orf223 hypothetical protein MGC45491 0.00079654438 0.002258606279 4.3997 0.1895 0.3826 1.0906 0.2356 0.2287 0.7128381 ARF5 ADP-ribosylation factor 5 1.57229846E-13 1.13106447E-11 4.3978 1.3106 2.7914 1.8475 1.4036 2.6154 2.38657465 WEE1 WEE1 G2 checkpoint kinase 7.98736292E-12 2.1979683E-10 4.3939 1.4254 2.5777 1.7717 0.9235 2.6272 2.26985686 PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 1.1360225E-16 1.3744062E-13 4.3930 3.4634 2.0580 1.5351 2.8664 3.2621 2.518157418 WDR18 WD repeat domain 18 1.98026577E-12 7.35683716E-11 4.3923 0.8163 3.0370 2.7982 0.7316 3.6542 2.7297267010 RNU12 RNA, U12 small nuclear pseudogene 1.47371023E-05 5.96535964E-05 4.3914 0.8746 1.5000 1.2325 0.6809 3.7842 0.6114135228 CD109 CD109 molecule 3.4447796E-10 4.76119613E-09 4.3871 2.1308 2.8485 1.5901 1.8572 3.2665 2.265279581 SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 6.21688325E-12 1.81461487E-10 4.3851 0.3321 0.3321 0.3321 0.3970 0.3970 0.39707222 TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.0208996382 0.04103128712 4.3851 0.5847 0.7859 0.5699 0.4655 0.6500 0.5352

60386 SLC25A19 1.29818874E-09 1.47423895E-08 4.3793 1.6484 1.8967 1.7266 1.5560 2.0876 2.01089476 NAPSA napsin A aspartic peptidase 7.44385343E-07 3.99102376E-06 4.3792 0.5823 1.5124 1.9162 0.3961 0.9472 1.133355861 DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 1.80422873E-05 7.18232405E-05 4.3760 0.8511 2.0614 1.8717 0.5752 1.5077 1.40225045 FURIN furin (paired basic amino acid cleaving enzyme) 4.71741225E-11 8.98817065E-10 4.3734 0.1468 0.9609 1.4691 0.2298 0.4740 0.72825817 PVR poliovirus receptor 4.20071968E-07 2.38741991E-06 4.3690 0.7544 0.8394 1.1229 0.3739 0.6250 2.08346517 SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.00363202591 0.00884268852 4.3690 1.1252 2.0646 1.9859 0.7085 1.4619 1.240129089 UBE2T ubiquitin-conjugating enzyme E2T (putative) 1.25799451E-07 8.1280324E-07 4.3679 1.3688 1.4091 1.3259 1.6485 1.6385 1.55718553 BHLHE40 basic helix-loop-helix family, member e40 1.2887728E-08 1.07038439E-07 4.3670 2.0956 3.0070 1.5893 1.1576 4.8408 3.11115905 RANGAP1 Ran GTPase activating protein 1 5.32901823E-15 1.15918835E-12 4.3665 0.8582 0.8520 1.0594 0.7485 1.1806 1.4399

23640 HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 6.05070673E-12 1.77177105E-10 4.3634 0.9346 2.5173 1.9978 1.1962 3.5951 1.98199221 NOLC1 nucleolar and coiled-body phosphoprotein 1 3.92211731E-10 5.29674261E-09 4.3603 1.6513 1.3592 1.7737 1.3193 2.8211 1.864627299 ADAMDEC1 ADAM-like, decysin 1 0.01967378066 0.038879441939 4.3580 0.0490 0.1405 0.0503 0.2204 0.1444 0.1223130340 AP1S3 adaptor-related protein complex 1, sigma 3 subunit 1.24620711E-06 6.35875351E-06 4.3575 1.2547 1.9042 1.7899 0.9415 2.4858 2.00934665 NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 5.34805434E-10 6.88166541E-09 4.3568 2.1743 2.0923 1.9465 2.3491 3.3950 3.057683858 ATAD3B ATPase family, AAA domain containing 3B 1.62418348E-11 3.82930072E-10 4.3563 0.7449 0.5150 1.0844 0.8891 0.7882 1.09053982 LIM2 lens intrinsic membrane protein 2, 19kDa 0.00886525803 0.019448432547 4.3540 0.1129 0.1002 0.3119 0.1312 0.0577 0.212151073 MRPL4 mitochondrial ribosomal protein L4 2.50275245E-13 1.61813867E-11 4.3498 1.4066 2.3078 1.8146 1.6169 4.4048 2.297279042 TSEN34 TSEN34 tRNA splicing endonuclease subunit 6.81782098E-10 8.46439166E-09 4.3482 0.9917 2.7955 1.9512 1.0880 3.8233 2.67003340 NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 1.44173494E-06 7.26113034E-06 4.3448 0.0341 0.1062 0.1471 0.1862 0.0207 0.14626472 SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 1.88869858E-12 7.10088486E-11 4.3439 1.1616 1.8004 1.5762 0.8597 2.0121 1.414457510 XPO5 exportin 5 2.14075586E-13 1.44873671E-11 4.3421 2.1137 3.5570 2.2490 0.8896 2.3476 0.9390257364 SNX33 SH3 andPX domain containing 3 1.8272723E-08 1.46181784E-07 4.3420 0.3649 1.3140 0.9863 0.5581 1.1220 0.790580185 TTI2 TELO2 interacting protein 2 1.27364214E-11 3.14911897E-10 4.3397 1.0540 1.5604 1.3040 1.0079 1.8958 1.33069242 MSC musculin 0.00049023828 0.001450628961 4.3397 0.7280 0.2349 0.3900 0.0860 0.1949 0.2141113655 MFSD3 major facilitator superfamily domain containing 3 4.60590873E-07 2.59190528E-06 4.3372 1.1716 1.6583 2.0328 0.7971 1.3309 3.04553304 HSPA1B heat shock 70kDa protein 1B 9.43291003E-10 1.11486502E-08 4.3369 0.6572 0.9188 0.6725 0.7270 0.9512 0.75393009 HIST1H1B histone cluster 1, H1b 1.504822E-08 1.23080159E-07 4.3333 2.5824 2.5331 1.5821 1.6734 2.4042 1.126055759 WDR12 WD repeat domain 12 5.54956891E-10 7.10593715E-09 4.3322 12.5909 0.7711 2.6521 3.6378 1.0107 0.0972254552 NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 7.88572614E-07 4.20204106E-06 4.3309 0.9578 2.9596 1.8696 0.9686 1.7137 1.9149100131094 LOC100131094 uncharacterized LOC100131094 6.22798632E-05 0.000223220412 4.3307 0.2524 0.0785 0.0894 1.1961 0.3394 0.04719718 ECE2 endothelin converting enzyme 2 2.96909093E-09 2.99896238E-08 4.3275 0.6382 1.4890 1.3352 0.2235 0.6203 0.31823620 IDO1 indoleamine 2,3-dioxygenase 1 0.00119967943 0.003281027174 4.3247 0.5167 0.3763 0.3285 0.5009 0.3156 0.22763954 LETM1 leucine zipper-EF-hand containing transmembrane protein 1 3.01189339E-13 1.84057913E-11 4.3186 0.7138 1.0901 1.0196 0.6810 1.5040 1.38138986 RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 4.1708775E-15 9.77054791E-13 4.3137 1.1500 1.8109 2.1333 0.6497 1.5344 1.746055177 RMDN3 regulator of microtubule dynamics 3 1.03911075E-16 1.36605311E-13 4.3135 1.5046 1.2141 1.6257 1.1837 1.6564 1.8672

10606 PAICS 2.26144326E-09 2.35582048E-08 4.3117 4.0424 1.9582 2.4762 4.0944 2.9671 3.9508653319 KIAA0895L KIAA0895-like 2.02755345E-06 9.88195696E-06 4.3059 0.8668 1.7059 1.5531 0.7464 1.5356 1.7781619279 ZNF704 zinc finger protein 704 8.91314601E-05 0.000309680555 4.3019 0.9010 1.4052 1.7512 0.5888 0.8190 1.17956628 SNRPB small nuclear ribonucleoprotein polypeptides B and B1 6.94415804E-16 3.62524731E-13 4.2990 2.3153 2.3071 1.8103 2.2546 3.2286 1.980279755 ZNF750 zinc finger protein 750 0.00198268475 0.005143851146 4.2945 0.0377 0.1138 0.0950 0.0321 0.0316 0.1945415116 PIM3 pim-3 oncogene 1.5788228E-11 3.74311742E-10 4.2930 1.4751 2.3030 1.5888 0.9871 2.2937 2.2223677823 SNORA42 small nucleolar RNA, H/ACA box 42 2.56633477E-06 1.22192107E-05 4.2921 0.0857 0.1473 0.1979 0.3363 0.3226 0.33906692 SPINT1 serine peptidase inhibitor, Kunitz type 1 2.037948E-06 9.92996956E-06 4.2905 1.1232 1.3274 1.7147 0.8901 1.7951 1.890357731 SPTBN4 spectrin, beta, non-erythrocytic 4 2.25058185E-05 8.77002165E-05 4.2840 0.7461 1.0632 0.9569 0.5640 0.7373 0.6582191 AHCY adenosylhomocysteinase 5.4188946E-11 1.00792905E-09 4.2811 0.8257 1.4937 1.3392 0.7418 2.0294 1.5852643382 TMEM253 transmembrane protein 253 0.01452555704 0.02991220311 4.2704 0.3321 0.3321 0.3321 0.3970 0.3970 0.39705717 PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 7.93987182E-15 1.51707465E-12 4.2670 1.6170 2.0700 1.5551 1.3214 3.7019 2.59225536 PPP5C protein phosphatase 5, catalytic subunit 5.19513233E-15 1.15762753E-12 4.2646 0.7490 1.4650 0.9857 0.5961 2.0168 1.202723138 N4BP3 NEDD4 binding protein 3 9.28057793E-06 3.92571721E-05 4.2614 1.1609 1.5033 1.1017 0.5468 1.5447 1.15802171 FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.8612897E-08 1.48513037E-07 4.2604 1.9228 1.2130 1.2680 1.5065 2.0308 2.15825255 PHKA1 phosphorylase kinase, alpha 1 (muscle) 4.93366331E-06 2.21602498E-05 4.2600 0.9056 0.8856 1.2839 0.7766 0.5915 0.89783291 HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 4.71858183E-05 0.000172954718 4.2589 1.0014 1.7297 1.1506 0.4577 0.9737 0.634984823 LMNB2 lamin B2 1.4055785E-09 1.56984904E-08 4.2586 2.1649 1.3472 1.3223 1.5394 1.2742 1.18507867 MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 3.89736896E-11 7.67821108E-10 4.2547 3.4897 2.1752 2.9260 1.7010 2.2196 5.292779084 WDR77 WD repeat domain 77 1.766836E-10 2.66806838E-09 4.2540 8.2745 17.0562 0.8953 3.1822 23.6084 0.57031944 EFNA3 ephrin-A3 9.48393428E-07 4.95965791E-06 4.2527 0.6211 0.9269 0.7929 0.4049 0.9656 0.59191802 DPH2 dipeptidyl-peptidase 4 9.60766541E-11 1.60174509E-09 4.2520 1.5474 2.1008 1.3161 1.4720 2.8994 1.2436201514 ZNF584 zinc finger protein 584 6.84494744E-09 6.16555427E-08 4.2434 1.6625 2.4042 2.1055 1.4403 2.6831 2.81554041 LRP5 low density lipoprotein receptor-related protein 5 2.85576675E-07 1.69362448E-06 4.2409 0.7735 0.5111 1.7813 0.5397 0.8859 2.1640283638 CEP170B KIAA0284 8.51617584E-09 7.38526649E-08 4.2404 0.5128 0.8995 1.1194 0.3156 0.5506 1.143964946 CENPH centromere protein H 4.41530936E-08 3.20144971E-07 4.2396 2.3586 3.8101 2.1570 2.3835 4.3181 2.370057568 SIPA1L2 signal-induced proliferation-associated 1 like 2 5.49129759E-06 2.44246815E-05 4.2395 0.0950 0.0755 0.1966 0.1625 0.0407 0.2163402682 UFSP1 UFM1-specific peptidase 1 (non-functional) 6.01770753E-06 2.64698007E-05 4.2395 1.6196 2.4834 2.3275 1.3060 2.4968 2.433184231 TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 5.27636506E-15 1.15918835E-12 4.2393 1.3675 4.6402 2.2879 1.0719 6.1988 2.373654555 DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 7.82563983E-14 6.77678157E-12 4.2390 4.5132 2.0937 2.3673 2.6937 1.5590 1.4132492303 GEMIN8P4 gem (nuclear organelle) associated protein 8 pseudogene 4 0.00345042456 0.008451227549 4.2376 0.0276 0.3112 0.4379 0.1979 0.2375 0.1660116729 PPP1R27 protein phosphatase 1, regulatory subunit 27 0.00271923497 0.006832489195 4.2354 0.0922 0.2679 0.4973 0.1146 0.1750 0.468579711 IPO4 importin 4 4.27743285E-12 1.35220161E-10 4.2342 0.5997 0.6700 0.7867 0.4603 0.6986 0.686810538 BATF basic leucine zipper transcription factor, ATF-like 1.21537564E-11 3.02693586E-10 4.2331 3.3837 3.5645 2.7158 2.6676 4.9078 2.864127143 PALD1 phosphatase domain containing, paladin 1 1.2101059E-05 4.99518386E-05 4.2263 1.0223 0.9437 1.1931 0.5511 0.6771 1.1279100506190 LINC00963 long intergenic non-protein coding RNA 963 3.10673869E-11 6.4433972E-10 4.2246 0.8768 1.5557 1.3176 0.3454 1.8587 1.36879343 EFTUD2 elongation factor Tu GTP binding domain containing 2 4.56573702E-14 4.76715125E-12 4.2212 1.5270 4.9140 1.6394 0.9738 3.7811 0.988457159 TRIM54 tripartite motif containing 54 0.00283933413 0.007098141094 4.2197 0.0290 0.0525 0.1319 0.1761 0.0663 0.16732189 FANCG Fanconi anemia, complementation group G 3.06570853E-09 3.08122257E-08 4.2177 2.1561 2.1962 2.0394 2.1202 2.3451 3.1501547 KIF1A kinesin family member 1A 0.00140962193 0.003787737058 4.2143 0.2022 0.8901 0.4641 0.1983 0.3419 0.49971174 AP1S1 adaptor-related protein complex 1, sigma 1 subunit 7.33029418E-10 8.98317474E-09 4.2127 1.0535 2.4774 1.5041 0.8240 2.3886 1.352610024 TROAP trophinin associated protein 1.26589427E-06 6.4466054E-06 4.2099 1.2196 2.4392 1.9691 0.9932 2.6411 2.417010293 TRAIP TRAF interacting protein 6.4535237E-06 2.82304968E-05 4.2082 1.3113 1.7686 2.1613 0.9417 1.5742 1.924465265 C8orf33 chromosome 8 open reading frame 33 6.29976615E-11 1.13455206E-09 4.2075 1.6647 1.9926 1.4977 1.4717 2.5585 2.209753615 MBD3 methyl-CpG binding domain protein 3 5.30339155E-14 5.25326898E-12 4.2070 1.7011 4.0790 1.6255 1.5392 5.4539 3.044210452 TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 6.24211189E-10 7.86050093E-09 4.2063 1.5429 2.9461 1.6425 1.2550 3.8862 1.719610849 CD3EAP CD3e molecule, epsilon associated protein 2.21355667E-08 1.73439569E-07 4.2054 0.8057 0.7511 3.0634 0.5932 0.3982 1.990084063 KIRREL2 kin of IRRE like 2 (Drosophila) 7.83201255E-05 0.00027578827 4.2050 1.3949 2.5886 1.6236 0.6613 1.8995 1.31061984 EIF5A eukaryotic translation initiation factor 5A 1.98482894E-11 4.52561066E-10 4.1996 1.5602 1.3222 1.7728 1.6057 2.1809 2.456154475 NLE1 notchless homolog 1 (Drosophila) 7.61059902E-11 1.31936305E-09 4.1965 2.0687 0.9307 1.2114 1.8571 1.5929 1.5086221150 SKA3 chromosome 13 open reading frame 3 1.05901663E-06 5.49257789E-06 4.1947 3.7349 6.8949 2.2176 1.6938 2.7565 1.26971019 CDK4 cyclin-dependent kinase 4 5.98689221E-12 1.76155386E-10 4.1906 3.0354 2.0288 2.6080 2.3230 2.5196 3.06135427 POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 6.59566648E-07 3.57826656E-06 4.1897 0.7398 1.0281 1.0301 0.7229 1.2392 1.15293627 CXCL10 chemokine (C-X-C motif) ligand 10 0.01129050184 0.024010713413 4.1856 0.3274 0.2719 0.4666 0.2387 0.3464 0.3247128854 TSPY26P testis specific protein, Y-linked 26, pseudogene 0.00033100881 0.0010190721 4.1839 1.0308 1.7593 1.6961 0.8215 1.0874 1.7236157313 CDCA2 cell division cycle associated 2 3.96896479E-06 1.81438391E-05 4.1829 1.2495 0.5629 1.6321 0.7075 0.3980 3.255857476 GRAMD1B GRAM domain containing 1B 4.95498601E-07 2.76113157E-06 4.1794 0.5220 0.4139 0.4581 0.3985 0.1318 0.349526330 GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.00029047094 0.000905096349 4.1768 1.2516 0.8377 1.1064 0.4442 0.8771 0.5254

7804 LRP8 7.54371164E-10 9.20766193E-09 4.1698 0.6495 0.7188 1.0253 0.4530 1.2581 1.577929941 PKN3 protein kinase N3 1.39189435E-09 1.55928332E-08 4.1668 1.4716 2.7023 1.6006 0.5877 2.6805 1.92238968 HIST1H3F histone cluster 1, H3f 2.6132471E-05 0.000100440158 4.1664 2.5320 3.6609 2.8383 2.6422 2.8742 3.6964

dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)

solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19

phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

11130 ZWINT ZW10 interacting kinetochore protein 2.95908785E-06 1.38993453E-05 4.1631 2.1620 1.6080 2.2304 2.4155 2.3209 2.821555135 WRAP53 WD repeat containing, antisense to TP53 9.86880952E-12 2.56831523E-10 4.1614 1.3207 1.0282 1.2375 1.4209 1.1532 1.1068100133121 FAM27B family with sequence similarity 27, member B 4.78716208E-07 2.68180934E-06 4.1592 1.4069 1.6726 1.6724 1.0979 2.1539 1.540325886 POC1A POC1 centriolar protein A 3.53802387E-06 1.63621291E-05 4.1568 1.7544 1.8784 2.0841 1.5813 2.3617 2.8340440028 LOC440028 uncharacterized LOC440028 0.00982319267 0.021303067124 4.1522 0.2136 1.2832 1.6745 0.2619 1.4818 0.57174007 PRICKLE3 prickle homolog 3 (Drosophila) 2.15958634E-09 2.26391059E-08 4.1518 1.1503 2.0207 1.4447 0.8083 2.3167 1.560680757 TMEM121 transmembrane protein 121 2.0225168E-08 1.60065973E-07 4.1498 0.5922 1.2019 1.0917 0.2528 0.7950 1.053164837 KLC2 kinesin light chain 2 6.03040957E-13 3.00238811E-11 4.1489 0.8918 1.1167 1.2271 0.5718 1.4247 1.20179415 FADS2 fatty acid desaturase 2 3.20224472E-06 1.49187699E-05 4.1484 1.2518 1.6067 1.1265 0.6648 1.4309 1.6842124454 EARS2 glutamyl-tRNA synthetase 2, mitochondrial 6.08603221E-09 5.56855185E-08 4.1479 0.0763 0.5464 0.4306 0.0535 0.4641 0.3257692148 SCARNA10 small Cajal body-specific RNA 10 6.35657661E-10 7.97715439E-09 4.1466 0.0843 0.1217 0.1765 0.1897 0.0307 0.2640220042 C11orf82 hypothetical protein FLJ25416 4.11283813E-06 1.87312508E-05 4.1435 1.5056 1.7556 2.5102 1.1652 1.7227 2.61293996 LLGL1 lethal giant larvae homolog 1 (Drosophila) 4.03326584E-14 4.49364838E-12 4.1431 1.1685 1.6829 1.9145 0.9234 1.4788 1.50982767 GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 5.86393091E-05 0.000211124622 4.1427 1.1553 1.6595 2.0469 0.5460 3.1068 1.698284126 ATRIP ATR interacting protein 6.29222128E-07 3.4319841E-06 4.1424 0.8875 1.4616 1.1127 0.9406 1.7608 1.2442121268 RHEBL1 Ras homolog enriched in brain like 1 2.37473528E-07 1.43679348E-06 4.1358 1.4591 3.1557 2.1353 1.0727 2.2279 2.056410131 TRAP1 TNF receptor-associated protein 1 1.30464083E-10 2.05942901E-09 4.1316 0.9411 2.1687 1.1725 0.7934 3.1073 1.408163967 CLSPN claspin homolog (Xenopus laevis) 9.6641321E-06 4.07154766E-05 4.1280 1.7834 2.2121 1.6761 1.8114 2.2471 2.59232356 FPGS folylpolyglutamate synthase 8.7375099E-13 3.90346653E-11 4.1277 0.8983 1.3159 1.1252 0.7570 1.5205 1.129155789 DEPDC1B DEP domain containing 1B 1.39026137E-05 5.66026231E-05 4.1228 2.5198 3.5499 1.9622 1.9947 3.1228 2.4262283899 INO80E coiled-coil domain containing 95 7.49656607E-11 1.30330405E-09 4.1222 0.8546 0.9391 0.6105 0.5767 0.3323 0.357683742 MARVELD1 MARVEL domain containing 1 0.00026064812 0.000821414702 4.1192 1.5466 2.5866 1.6983 1.3319 2.3817 2.15474175 MCM6 minichromosome maintenance complex component 6 2.40375021E-10 3.50809295E-09 4.1170 1.4143 3.7885 1.4888 1.0135 3.5347 1.929881890 QTRT1 queuine tRNA-ribosyltransferase 1 4.17460008E-10 5.57589859E-09 4.1150 1.9295 3.0978 2.0016 1.3737 4.6346 1.8794402665 IGLON5 IgLON family member 5 0.00096989273 0.002702329968 4.1142 0.0918 0.0969 0.1679 0.2116 0.1699 0.25583376 IARS isoleucyl-tRNA synthetase 6.67378909E-11 1.18853289E-09 4.1124 0.6976 1.6111 0.8742 0.8390 1.4780 0.9077100128881 VPS9D1-AS1 VPS9D1 antisense RNA 1 5.51851321E-07 3.0454326E-06 4.1096 0.5715 0.7962 1.0672 0.4537 0.8607 1.148923464 GCAT glycine C-acetyltransferase 2.16883117E-09 2.27099617E-08 4.1091 2.3914 1.4288 2.5754 1.5911 1.0360 2.3807548321 FAM27A family with sequence similarity 27, member A 1.18013639E-06 6.05374851E-06 4.1085 1.5006 1.5699 1.6894 1.1586 1.3131 1.66745328 PLAU plasminogen activator, urokinase 0.02479491501 0.047529656629 4.1040 0.9274 1.2037 1.8008 0.5986 0.8481 1.2538339983 NAT8L N-acetyltransferase 8-like (GCN5-related, putative) 0.0019853707 0.005149282249 4.1010 0.4482 1.3562 0.8808 1.4838 0.6575 1.2166

124044 SPATA2L spermatogenesis associated 2-like,spermatogenesis associated 2-like 3.5444355E-12 1.17113789E-10 4.0983 1.4658 3.5426 1.3428 0.9500 3.4807 2.05837127 TNFAIP2 tumor necrosis factor, alpha-induced protein 2 3.74850158E-05 0.000140181377 4.0970 0.0314 0.1773 0.1333 0.1091 0.3068 0.16037813 EVI5 ecotropic viral integration site 5 3.2152964E-07 1.88542669E-06 4.0970 0.0825 0.0551 0.0725 0.4246 0.0633 0.174356931 DUS3L dihydrouridine synthase 3-like (S. cerevisiae) 2.29386393E-11 5.04981707E-10 4.0953 1.1999 1.4622 1.1136 1.1808 1.8395 1.570011004 KIF2C kinesin family member 2C 1.38051854E-06 6.98555382E-06 4.0938 1.2364 1.5740 1.4059 1.2875 1.9516 1.33695973 RENBP renin binding protein 7.43576906E-06 3.21425059E-05 4.0909 0.8445 1.4768 1.7239 0.6848 0.9976 1.1792147111 NOTUM notum pectinacetylesterase homolog (Drosophila) 0.00098148501 0.002732128891 4.0877 1.0151 0.9052 1.1029 0.4284 0.4980 0.63156442 SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.02616732765 0.04975332059 4.0877 0.1131 0.0814 0.1682 0.4123 0.2398 0.477610576 CCT2 chaperonin containing TCP1, subunit 2 (beta) 8.72753005E-12 2.32124351E-10 4.0870 2.8953 2.0917 1.4325 2.2561 1.8876 1.5117284648 LOC284648 hypothetical protein LOC284648 0.02092405431 0.041065898191 4.0867 2.2197 3.8962 2.5043 1.5579 2.5656 1.95385192 PEX10 peroxisomal biogenesis factor 10 5.57887888E-08 3.92670551E-07 4.0864 0.8449 3.7352 1.8906 0.7466 6.1116 2.59261164 CKS2 CDC28 protein kinase regulatory subunit 2 8.48890551E-11 1.44287704E-09 4.0831 1.1114 3.1956 1.6110 0.9947 5.9880 3.6550135 ADORA2A adenosine A2a receptor 1.93400445E-05 7.63902493E-05 4.0789 0.8954 1.7433 1.2353 0.6458 1.5621 0.840584733 CBX2 chromobox homolog 2 (Pc class homolog, Drosophila) 3.48392544E-05 0.00013087641 4.0764 1.5340 2.1442 1.9128 0.7757 0.9721 1.492892579 G6PC3 glucose 6 phosphatase, catalytic, 3 3.92064399E-08 2.87702839E-07 4.0731 1.7196 1.4905 1.8007 1.2021 1.9996 1.8134650623 BEND3P3 hypothetical LOC650623 2.72802318E-07 1.62578081E-06 4.0728 0.0978 0.0802 0.0594 0.1295 0.0428 0.17672224 FDPS farnesyl diphosphate synthase 1.47943931E-11 3.55688357E-10 4.0713 2.1957 2.3360 2.2209 1.8050 2.8555 2.686494059 LENG9 leukocyte receptor cluster (LRC) member 9 1.72101598E-06 8.53362388E-06 4.0711 1.2875 1.3373 2.4549 0.8517 1.4757 3.339157462 KIAA1161 KIAA1161 0.00012192549 0.000411520134 4.0705 2.2061 1.6781 2.0067 1.4417 1.4998 1.916879746 ECHDC3 enoyl CoA hydratase domain containing 3 0.00331535787 0.008152095152 4.0701 1.1163 1.1040 1.6387 0.6490 0.7050 1.68904648 MYO7B myosin VIIB 0.00080924882 0.002291877412 4.0672 0.2314 0.6968 0.3934 0.1511 0.2812 0.24848364 HIST1H4C histone cluster 1, H4c 6.63425607E-09 6.00401817E-08 4.0649 1.4988 0.8504 1.3791 1.4789 0.5714 0.950210669 CGREF1 cell growth regulator with EF-hand domain 1 0.00040683026 0.001227882799 4.0524 0.3133 0.5594 0.4964 0.2454 0.6415 0.4512282974 STK32C serine/threonine kinase 32C 3.59521032E-11 7.20303541E-10 4.0501 0.8088 1.0980 1.2642 0.7446 1.1150 0.9807

57480 PLEKHG1 3.89525232E-09 3.80406469E-08 4.0464 0.9222 0.6982 0.8533 0.6929 0.5320 0.7273348738 C2orf48 chromosome 2 open reading frame 48 0.00585892456 0.013505016986 4.0462 0.5537 0.6574 0.5026 0.3160 0.2803 0.23746522 SLC4A2 solute carrier family 4 (anion exchanger), member 2 7.14772263E-11 1.25943286E-09 4.0454 0.8711 1.9068 1.5708 0.7750 2.0384 1.22965778 PTPN7 protein tyrosine phosphatase, non-receptor type 7 8.93572414E-15 1.58061002E-12 4.0430 1.4033 2.1243 2.3723 0.9500 2.5590 2.24684085 MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 2.55515372E-07 1.53376375E-06 4.0416 2.2994 1.5385 1.6798 2.3535 1.8664 2.576511169 WDHD1 WD repeat and HMG-box DNA binding protein 1 3.09479041E-08 2.31849161E-07 4.0392 0.1769 1.4057 0.2267 0.2780 0.6982 0.210251548 SIRT6 sirtuin 6 1.48051837E-12 5.91948178E-11 4.0392 3.2559 1.6237 2.2199 1.7883 1.3420 2.731484069 PLEKHN1 pleckstrin homology domain containing, family N member 1 1.479505E-05 5.98748957E-05 4.0391 1.5074 2.2616 1.9048 1.0989 2.5868 1.849981570 CLPB ClpB caseinolytic peptidase B homolog (E. coli) 4.70929412E-11 8.98206912E-10 4.0384 0.5952 0.7603 0.8627 0.7765 0.5817 0.945566005 CHID1 chitinase domain containing 1 6.46532606E-12 1.86921579E-10 4.0364 0.4691 1.3832 0.7405 0.4123 2.0467 0.9475196264 MPZL3 myelin protein zero-like 3 3.12519171E-08 2.3374336E-07 4.0362 2.0066 2.6408 1.1861 2.0236 3.6638 1.632780210 ARMC9 armadillo repeat containing 9 4.95987101E-06 2.22615483E-05 4.0360 1.3753 2.7635 1.6095 1.3773 3.1133 1.93257133 TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.12980613E-12 4.73482053E-11 4.0343 1.6010 1.4065 1.7237 1.2994 2.1324 2.710790381 TICRR TOPBP1-interacting checkpoint and replication regulator 2.00014177E-05 7.87811824E-05 4.0322 1.7733 2.5002 1.8197 1.7383 1.9448 2.011865990 FAM173A family with sequence similarity 173, member A 5.30673605E-10 6.84295561E-09 4.0316 1.5373 2.7795 1.9677 0.6934 2.7253 2.012322820 COPG1 coatomer protein complex, subunit gamma 3.70981003E-13 2.11830153E-11 4.0314 2.9281 2.2858 2.4842 2.5259 2.9742 3.1430201255 LRRC45 leucine rich repeat containing 45 3.75411316E-10 5.1228645E-09 4.0304 0.8009 0.6062 1.7120 0.8333 0.4030 1.1392653820 FAM72B family with sequence similarity 72, member B 4.61959407E-08 3.32712743E-07 4.0268 0.9721 2.1938 1.8273 0.7963 2.2141 2.06576183 MRPS12 mitochondrial ribosomal protein S12 1.17515847E-15 4.71210315E-13 4.0228 1.6629 22.5529 1.6299 0.3967 3.0490 0.5536100532746 PPT2-EGFL8 PPT2-EGFL8 readthrough (NMD candidate) 0.00049535058 0.001464807539 4.0225 0.3584 0.4191 0.7903 0.3782 0.5772 0.5752284403 WDR62 WD repeat domain 62 1.23169072E-06 6.29347117E-06 4.0218 0.5050 0.4496 1.9297 0.7788 0.1386 1.0377100129066 UNQ6494 uncharacterized LOC100129066 0.00425194523 0.010195466518 4.0172 0.0733 0.3540 0.1090 0.1706 0.1391 0.173451127 TRIM17 tripartite motif containing 17 2.6066138E-05 0.000100227372 4.0136 1.4670 1.4833 1.2344 0.8118 1.0905 0.9345666 BOK BCL2-related ovarian killer 0.00689201145 0.015583570498 4.0128 0.0728 0.0307 0.3214 0.0342 0.0748 0.1156160 AP2A1 adaptor-related protein complex 2, alpha 1 subunit 2.43521523E-15 6.74185646E-13 4.0118 0.6460 0.8635 0.7220 0.4716 1.2347 0.829783596 BCL2L12 BCL2-like 12 (proline rich) 5.14596482E-10 6.65914088E-09 4.0108 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970109 ADCY3 adenylate cyclase 3 2.17340734E-11 4.87868537E-10 4.0090 0.7611 0.8223 0.9541 0.5112 0.9557 0.671381848 SPRY4 sprouty homolog 4 (Drosophila) 0.00049601571 0.001466299803 4.0085 1.7819 2.0193 2.3217 0.9294 1.5526 2.0393440044 SLC22A20 solute carrier family 22, member 20 0.00011517893 0.000390382025 4.0068 0.2935 0.1945 0.3591 0.1811 0.0575 0.307455379 LRRC59 leucine rich repeat containing 59 6.8941851E-10 8.50577651E-09 4.0053 2.2780 1.4432 1.5300 1.8439 1.6350 1.47012639 GCDH glutaryl-CoA dehydrogenase 2.67210022E-10 3.85660468E-09 4.0019 1.9278 2.1844 1.9280 1.7463 3.2751 1.5997246182 AKR7A2P1 AKR7 family pseudogene 0.00165817653 0.004383420361 4.0002 0.0341 0.1317 0.0738 0.3219 0.0980 0.158754438 GFOD1 glucose-fructose oxidoreductase domain containing 1 9.54196777E-08 6.35157869E-07 3.9984 0.6589 1.0688 1.0086 0.5435 1.0837 1.00953383 ICAM1 intercellular adhesion molecule 1 9.56762646E-08 6.36633906E-07 3.9980 1.4191 2.2152 1.9385 0.9249 1.7176 1.944729984 RHOD ras homolog family member D 5.83244214E-05 0.00021007369 3.9965 0.6875 1.4449 1.3482 0.4422 0.7394 0.724583985 SPNS1 spinster homolog 1 (Drosophila) 1.36977575E-09 1.53954057E-08 3.9964 2.3580 2.5401 1.9468 1.7125 2.7198 2.36046300 MAPK12 mitogen-activated protein kinase 12 5.5735694E-09 5.16955635E-08 3.9960 0.2471 1.2074 1.0611 0.0954 0.6669 0.683523516 SLC39A14 solute carrier family 39 (zinc transporter), member 14 6.61561159E-07 3.58589306E-06 3.9948 1.8418 3.8881 2.4156 1.2980 4.7969 2.5603574042 SNORA10 small nucleolar RNA, H/ACA box 10 1.08325092E-07 7.11728185E-07 3.9942 1.1469 0.8538 0.8843 1.2482 0.7321 0.47638444 DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 0.00010167414 0.000349011817 3.9928 2.7086 1.5875 2.3244 2.1474 1.2376 2.1116875 CBS cystathionine-beta-synthase 8.84955815E-05 0.000307822438 3.9887 1.4074 1.5450 0.7460 0.6060 0.9566 1.117611332 ACOT7 acyl-CoA thioesterase 7 3.47336858E-07 2.01926156E-06 3.9838 0.8484 1.5675 1.1327 0.5829 1.9127 0.9153197335 WDR90 WD repeat domain 90 7.64783441E-06 3.29578373E-05 3.9825 0.7078 0.7484 0.7211 0.5530 0.7777 0.82913601 IL15RA interleukin 15 receptor, alpha 4.46127701E-11 8.58972113E-10 3.9818 1.5303 1.3778 1.4277 1.7708 1.7923 2.17198438 RAD54L RAD54-like (S. cerevisiae) 2.05085854E-06 9.98754988E-06 3.9786 1.6408 1.6637 2.3056 1.1045 1.4319 2.92292785 GNG3 guanine nucleotide binding protein (G protein), gamma 3 0.00282402529 0.007065607454 3.9777 0.3321 0.3321 0.3321 0.3970 0.3970 0.397026153 KIF26A kinesin family member 26A 0.01233738879 0.025956790417 3.9774 1.0002 2.1738 0.9755 0.4832 2.5170 0.650455226 NAT10 N-acetyltransferase 10 (GCN5-related) 1.07310482E-12 4.55994679E-11 3.9738 2.5572 2.8862 1.6896 1.7726 3.7822 1.7167203068 TUBB tubulin, beta 7.86505621E-10 9.53618495E-09 3.9722 0.6146 0.5574 0.5415 0.6383 0.7540 0.7086196483 FAM86A family with sequence similarity 86, member A 8.17921021E-08 5.54753263E-07 3.9718 1.0496 2.2425 1.7458 0.9408 2.5348 2.3327100127888 LOC100127888 uncharacterized LOC100127888 0.00067824549 0.001944594645 3.9707 0.0558 0.3045 0.1547 0.0692 0.0593 0.1205891 CCNB1 cyclin B1 3.31773349E-07 1.93865131E-06 3.9706 1.9257 3.0808 2.5255 1.2379 2.5730 2.812255057 AIM1L absent in melanoma 1-like 0.00059223523 0.001721221908 3.9691 0.0843 0.2389 0.2907 0.1448 0.0800 0.213510061 ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 3.04481462E-14 3.73388273E-12 3.9667 1.0652 0.8650 1.1686 1.3399 1.2431 1.3720

10940 POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) 5.4816874E-09 5.08691682E-08 3.9666 1.0076 1.8813 1.1819 1.0150 1.7034 0.4783388323 GLTPD2 glycolipid transfer protein domain containing 2 0.00029236808 0.000910231663 3.9654 0.6225 1.1537 0.9011 0.3808 1.1173 0.8193

25902 MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 7.64150436E-08 5.22355285E-07 3.9653 0.8948 1.3648 1.0643 0.5744 1.0308 1.4198645121 CCNI2 similar to cyclin I 3.14257762E-05 0.000118909046 3.9649 1.3868 2.4834 1.5186 1.4799 2.0659 1.381883460 EMC6 ER membrane protein complex subunit 6 1.18388902E-08 9.90477115E-08 3.9633 1.0624 2.2858 2.8242 0.4557 1.8733 0.43368800 PEX11A peroxisomal biogenesis factor 11 alpha 0.00011726065 0.000397143021 3.9626 0.0949 0.4091 0.2268 0.1102 0.5185 0.0971197342 EME2 essential meiotic structure-specific endonuclease subunit 2 1.97731939E-06 9.66031549E-06 3.9599 1.7196 0.9577 2.6095 0.8869 1.1702 2.847464928 MRPL14 mitochondrial ribosomal protein L14 2.9910191E-17 8.75611785E-14 3.9515 2.3127 2.7401 4.0247 1.2368 2.9408 2.49314881 NPR1 natriuretic peptide receptor 1 0.00282718111 0.007071629467 3.9491 0.6505 0.4994 0.8354 0.3579 0.2429 0.6480286319 TUSC1 tumor suppressor candidate 1 3.35608126E-05 0.000126307553 3.9485 0.4170 0.7186 0.5726 0.5002 0.6553 0.609964175 LEPRE1 leucine proline-enriched proteoglycan (leprecan) 1 1.16281586E-15 4.71210315E-13 3.9470 3.5013 1.7083 5.4530 1.0809 2.6238 6.279926995 TRUB2 TruB pseudouridine (psi) synthase family member 2 5.84712041E-12 1.73721275E-10 3.9448 0.1963 0.8904 3.1931 0.3206 0.3638 0.357155723 ASF1B anti-silencing function 1B histone chaperone 5.92631461E-06 2.61370071E-05 3.9431 0.9056 0.9076 4.2922 0.7571 0.5197 3.1213677811 SNORA28 small nucleolar RNA, H/ACA box 28 0.00010134418 0.00034800992 3.9418 0.4254 0.5287 0.4668 0.4592 0.6424 0.364556924 PAK6 p21 protein (Cdc42/Rac)-activated kinase 6 0.00100187552 0.002782107829 3.9404 0.1849 0.4001 0.4744 0.2849 0.1015 0.4241146760 RTN4RL1 reticulon 4 receptor-like 1 0.00127142164 0.003456027407 3.9398 1.5135 1.6653 1.6055 1.0093 1.1448 1.6734653308 ASAH2B N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B 2.62264716E-05 0.000100737879 3.9397 2.3972 1.6043 1.7481 2.2467 1.2871 2.30458361 HIST1H4F histone cluster 1, H4f 1.51680503E-08 1.23838523E-07 3.9380 1.9511 2.8596 1.9340 2.0436 2.8919 1.5301100132948 FAM27C family with sequence similarity 27, member C 5.09253113E-06 2.2795377E-05 3.9370 1.3060 1.7385 1.7058 0.8639 1.4533 1.78347037 TFRC transferrin receptor 2.4387255E-09 2.51753629E-08 3.9369 2.4131 2.2657 2.2000 1.8782 3.6799 2.80394914 NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.00036411768 0.001108490216 3.9359 1.0997 3.1660 2.8994 0.5694 1.6545 2.3077219293 ATAD3C ATPase family, AAA domain containing 3C 6.00887572E-08 4.20667345E-07 3.9339 0.1011 0.0261 0.1201 0.1394 0.0132 0.09766566 SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 2.93054718E-10 4.15927555E-09 3.9325 2.5120 3.0809 1.9616 2.5442 5.0432 3.3859

23657 SLC7A11 0.00414004828 0.009953547645 3.9309 6.0588 3.1797 2.9445 4.6803 2.3656 2.629379047 KCTD15 potassium channel tetramerization domain containing 15 0.00042497934 0.001273613655 3.9297 0.6386 1.7657 1.2569 0.4866 1.6819 1.32311493 CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.26772869E-07 8.18513734E-07 3.9267 2.1215 1.4585 1.5864 1.6792 1.9481 1.98099424 KCNK6 potassium channel, subfamily K, member 6 6.50289986E-12 1.87414805E-10 3.9262 0.6174 0.7780 0.9950 0.3938 0.8663 1.057885409 NKD2 naked cuticle homolog 2 (Drosophila) 0.00092929533 0.002601115842 3.9191 0.4530 1.2804 0.5892 0.2627 0.7184 0.787710535 RNASEH2A ribonuclease H2, subunit A 4.97858409E-09 4.70122421E-08 3.9168 1.1383 0.9217 1.9569 0.9716 0.8516 2.2801283345 RPL13P5 RPL13-2 pseudogene 0.00016143194 0.00052937623 3.9154 0.1237 0.0323 0.1917 0.5371 0.1184 0.0950

pleckstrin homology domain containing, family G (with RhoGef domain) member 1

solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11

970 CD70 CD70 molecule 0.00025310379 0.00079901734 3.9105 1.3243 2.8975 2.5689 1.1613 1.3157 1.667665268 WNK2 WNK lysine deficient protein kinase 2 2.52428273E-05 9.73279048E-05 3.9079 0.4947 0.4918 0.4139 0.3258 0.3415 0.424455143 CDCA8 cell division cycle associated 8 1.66393811E-06 8.27530681E-06 3.9075 0.4116 1.3154 3.0578 0.0724 0.5504 1.72219526 MPDU1 mannose-P-dolichol utilization defect 1 5.11053172E-11 9.5577928E-10 3.9069 0.9110 1.3126 1.9495 1.1989 2.1478 1.7906140691 TRIM69 tripartite motif-containing 69 2.93741185E-09 2.9686056E-08 3.9058 2.2553 2.0310 2.0658 1.5297 2.2442 2.091311033 ADAP1 ArfGAP with dual PH domains 1 7.55397876E-07 4.04413419E-06 3.9018 0.2310 0.4819 0.5379 0.2723 0.3987 0.4189126549 ANKLE1 ankyrin repeat domain 41 6.84926772E-07 3.70265739E-06 3.8977 1.2015 1.5039 1.4416 1.0220 0.9218 1.43026737 TRIM21 tripartite motif containing 21 2.1248646E-09 2.23135207E-08 3.8971 1.5060 2.2601 1.7843 1.3118 3.4081 2.044279583 TMEM231 transmembrane protein 231 8.3105918E-07 4.40659122E-06 3.8967 1.0364 1.3211 1.0437 0.7467 1.0210 0.942727077 B9D1 B9 protein domain 1 0.00028816781 0.000898532809 3.8955 0.7038 0.5777 0.8517 0.7027 0.7450 1.156479019 CENPM centromere protein M 5.47390388E-09 5.08481617E-08 3.8942 1.6325 1.7595 2.1623 1.2301 1.7305 1.88603801 KIFC3 kinesin family member C3 0.00035957767 0.001096678882 3.8928 0.0947 0.2054 0.2705 0.1432 0.0648 0.27175983 RFC3 replication factor C (activator 1) 3, 38kDa 1.21186378E-07 7.85776261E-07 3.8863 1.8956 1.9107 2.0738 1.5191 2.5103 2.3658

8792 TNFRSF11A 0.00014393423 0.000477914989 3.8858 0.4099 1.2235 1.2049 0.5241 1.1544 1.329110362 HMG20B high mobility group 20B 4.38860888E-15 1.01504635E-12 3.8855 1.0592 1.2355 1.6928 0.8162 1.9204 1.9461100302743 SNORA80B small nucleolar RNA, H/ACA box 80B 1.15109316E-07 7.50902329E-07 3.8836 0.7655 2.4402 2.7655 0.4424 2.3145 1.31079294 S1PR2 sphingosine-1-phosphate receptor 2 1.16974961E-11 2.94742065E-10 3.8826 0.7312 0.4171 0.9671 0.5196 0.3591 0.900154620 FBXL19 F-box and leucine-rich repeat protein 19 8.6437281E-13 3.87103431E-11 3.8822 0.7085 2.6541 1.2059 0.4784 2.4043 1.1435122970 ACOT4 acyl-CoA thioesterase 4 7.92630351E-05 0.000278786175 3.8815 0.9984 1.7040 1.3710 1.2985 0.9840 1.48335709 PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.48405176E-14 2.29801642E-12 3.8808 2.3877 1.9475 2.8106 1.9911 2.5183 2.458379012 CAMKV CaM kinase-like vesicle-associated 0.00253024533 0.006409627435 3.8805 0.6053 1.7696 1.2429 0.6006 1.0464 0.587129775 CARD10 caspase recruitment domain family, member 10 0.00510426083 0.011993962697 3.8786 0.2046 0.6990 0.2864 0.1412 0.6195 0.31759277 WDR46 WD repeat domain 46 4.98980525E-14 5.09350399E-12 3.8778 0.4203 0.5881 0.5939 0.5347 0.4894 0.55124221 MEN1 multiple endocrine neoplasia I 9.59231214E-16 4.17311256E-13 3.8736 1.2086 1.7004 1.1366 1.1491 1.6380 1.502591107 TRIM47 tripartite motif containing 47 2.70092617E-11 5.7924088E-10 3.8719 1.4912 1.6270 1.8744 1.0390 1.3116 1.75379945 GFPT2 glutamine-fructose-6-phosphate transaminase 2 0.01335651095 0.027816670504 3.8714 1.5019 1.6667 1.4784 0.8188 1.0934 1.6881171389 NLRP6 NLR family, pyrin domain containing 6 9.34421837E-07 4.8949988E-06 3.8714 0.6458 2.9543 1.3112 0.4943 2.0292 1.18937407 VARS valyl-tRNA synthetase 1.34679361E-11 3.31206095E-10 3.8710 0.3946 0.4663 0.4356 0.4418 0.6380 0.530184940 CORO6 coronin 6 5.97463975E-05 0.000214772019 3.8706 0.6182 1.4175 1.3967 0.4319 1.0511 1.01364953 ODC1 ornithine decarboxylase 1 5.08001232E-08 3.61738056E-07 3.8705 1.2646 3.2430 2.4434 1.5295 3.4652 2.89986721 SREBF2 sterol regulatory element binding transcription factor 2 1.52662365E-09 1.68852708E-08 3.8672 0.8343 1.3336 1.1295 0.9189 1.7005 1.71165524 PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 8.90298589E-16 4.17311256E-13 3.8646 2.2760 1.8551 1.9669 1.2515 1.7233 1.6313242 ALOX12B arachidonate 12-lipoxygenase, 12R type 2.6628054E-06 1.26244889E-05 3.8622 0.0235 0.0398 0.5659 0.1598 1.5266 0.16407283 TUBG1 tubulin, gamma 1 4.65037344E-10 6.1167015E-09 3.8619 13.3130 1.8943 3.1746 10.8434 1.8382 3.277455954 ZMAT5 zinc finger, matrin-type 5 3.58845758E-08 2.64815416E-07 3.8606 1.7312 2.6518 2.0639 0.9446 1.2973 0.960060673 C12orf44 chromosome 12 open reading frame 44 1.06784302E-11 2.74425143E-10 3.8602 1.7268 1.4496 2.5272 1.6118 1.9983 2.574525837 RAB26 RAB26, member RAS oncogene family 5.6511434E-05 0.000204026264 3.8578 0.6759 1.0448 1.0293 0.2677 0.5385 0.80245479 PPIB peptidylprolyl isomerase B (cyclophilin B) 3.88989399E-10 5.26100244E-09 3.8573 2.0965 1.8066 1.5234 1.5147 1.7949 1.537251734 MSRB1 methionine sulfoxide reductase B1 8.02771795E-08 5.46100009E-07 3.8547 1.2401 2.4823 2.3175 0.7529 1.7089 2.1781677822 SNORA40 small nucleolar RNA, H/ACA box 40 5.84314627E-06 2.58263108E-05 3.8546 0.9598 2.4268 0.8919 0.6035 1.4615 0.468080781 COL18A1 collagen, type XVIII, alpha 1 3.01834181E-10 4.25548932E-09 3.8544 0.3944 0.6441 0.4522 0.2524 0.3823 0.452164651 CSRNP1 AXIN1 up-regulated 1 2.14693786E-10 3.1712893E-09 3.8500 0.8717 1.8012 1.0927 1.1369 1.4991 1.551950628 GEMIN4 gem (nuclear organelle) associated protein 4 1.40579345E-11 3.42488772E-10 3.8489 16.7699 0.7053 1.8743 10.7305 1.8959 1.501185301 COL27A1 collagen, type XXVII, alpha 1 0.00010530405 0.000360321287 3.8487 0.4959 1.0981 0.8117 0.5083 1.1805 0.70999477 MED20 mediator complex subunit 20 1.99949922E-09 2.11550954E-08 3.8434 0.9895 0.3970 1.7679 0.2550 0.3519 1.12019915 ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.0061009265 0.013993990592 3.8417 0.1456 0.4397 0.4718 0.3181 0.0732 0.47685687 PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 6.10619736E-10 7.71060389E-09 3.8414 2.7934 2.6346 2.1513 3.2127 3.9677 2.5573158158 RASEF RAS and EF-hand domain containing 2.30610368E-05 8.96534604E-05 3.8399 0.1083 0.0142 0.2938 0.1119 0.0505 0.242756992 KIF15 kinesin family member 15 2.6355245E-06 1.25113805E-05 3.8377 1.0632 0.0716 1.5126 0.2566 0.1523 1.247410212 DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 6.27678315E-12 1.82917674E-10 3.8366 0.8009 1.0345 0.9283 0.8320 1.7938 1.401010856 RUVBL2 RuvB-like AAA ATPase 2 6.2023506E-11 1.12425139E-09 3.8326 0.9735 2.4918 1.8620 0.4699 1.5204 1.0399143903 LAYN layilin 0.00693239628 0.01565551166 3.8306 2.1949 1.4572 1.6801 1.5042 1.3471 1.541323770 FKBP8 FK506 binding protein 8, 38kDa 1.41813596E-14 2.23380864E-12 3.8303 1.4943 1.6710 1.8433 0.8952 0.9089 1.716384634 KISS1R KISS1 receptor 0.00031297531 0.000968940161 3.8282 1.4133 2.5542 2.2449 0.6303 1.8068 2.0387114897 C1QTNF1 C1q and tumor necrosis factor related protein 1 0.00572503304 0.013239818217 3.8276 0.2202 0.2495 0.3313 0.2167 0.1404 0.270879850 FAM57A family with sequence similarity 57, member A 5.17938855E-08 3.6809719E-07 3.8267 1.0651 1.2683 1.4103 0.9460 1.9123 1.580155352 COPRS coordinator of PRMT5, differentiation stimulator 6.4553117E-10 8.08994893E-09 3.8259 1.9052 1.1858 1.3514 1.4829 1.2987 1.1644122769 LRR1 leucine rich repeat protein 1 1.18824226E-10 1.91493418E-09 3.8198 3.5901 2.1256 1.9799 3.9914 3.6055 3.711543 ACHE acetylcholinesterase (Yt blood group) 0.00086850639 0.002446708099 3.8197 1.0090 1.2012 0.7317 0.7867 1.1904 0.45205696 PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.21969662E-13 9.24742602E-12 3.8171 0.6185 0.8505 0.7627 0.6171 0.8012 0.7840158055 C9orf163 chromosome 9 open reading frame 163 0.00731438056 0.016400584323 3.8170 0.3321 0.3321 0.3321 0.3970 0.3970 0.397011313 LYPLA2 lysophospholipase II 1.33389544E-15 4.97406887E-13 3.8159 2.8299 3.9743 1.6730 2.5096 4.4174 1.6880

136853 SRCRB4D 8.65623196E-05 0.000301844791 3.8156 0.8019 1.0981 0.9759 0.6953 1.0891 0.930330000 TNPO2 transportin 2 5.24457982E-14 5.25019358E-12 3.8128 2.4253 2.9175 2.0918 1.9431 4.5064 2.49231537 CYC1 cytochrome c-1 2.15468417E-13 1.45278189E-11 3.8100 1.8492 2.6614 1.8245 0.9110 2.7737 2.72035688 PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 7.19786186E-16 3.65331478E-13 3.8097 5.1194 4.3504 3.5204 2.6563 7.0203 5.911711338 U2AF2 U2 small nuclear RNA auxiliary factor 2 1.16559182E-10 1.89312833E-09 3.8070 1.4536 1.7835 1.8195 1.9774 2.6088 3.14639361 LONP1 lon peptidase 1, mitochondrial 8.94580804E-11 1.5120981E-09 3.8062 2.7108 2.6798 1.9578 1.4187 5.0050 3.26272819 GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 0.01666286268 0.033671234785 3.8055 0.0697 0.1505 0.2779 0.1825 0.0910 0.18342740 GLP1R glucagon-like peptide 1 receptor 0.00541652009 0.012610049151 3.8044 0.4943 1.6414 1.0779 0.4861 0.5051 0.837555969 C20orf24 chromosome 20 open reading frame 24 1.75425469E-09 1.90004397E-08 3.8020 2.1652 4.4687 1.8222 1.6768 6.4498 2.388310498 CARM1 coactivator-associated arginine methyltransferase 1 7.46574501E-15 1.4691205E-12 3.8008 0.5109 1.7602 0.9676 0.2961 1.5493 1.20251736 DKC1 dyskeratosis congenita 1, dyskerin 1.17537143E-12 4.85891104E-11 3.7991 2.4712 1.5367 2.0417 1.8070 2.4208 2.566579989 TTC26 tetratricopeptide repeat domain 26 0.0001056024 0.000361139241 3.7976 3.3479 1.5916 1.5441 2.8621 1.8105 1.16712886 GRB7 growth factor receptor-bound protein 7 0.00272284886 0.006838748362 3.7969 0.4109 0.6121 0.7493 0.2897 0.2178 0.43893049 HBQ1 hemoglobin, theta 1 0.00709750628 0.015990830415 3.7961 1.1201 1.2650 1.0150 0.6382 0.4829 0.82176652 SORD sorbitol dehydrogenase 1.54028703E-10 2.37904687E-09 3.7933 1.9559 2.1367 2.0788 1.3319 2.7204 1.9675286002 SLC26A4-AS1 hypothetical protein LOC286002 0.02122489232 0.041562665574 3.7932 0.8001 1.2660 1.6137 0.4241 1.0779 1.311684261 FBXW9 F-box and WD repeat domain containing 9 2.16324581E-07 1.3220322E-06 3.7906 1.2926 2.8817 2.3135 1.7340 2.8920 2.022110825 NEU3 sialidase 3 (membrane sialidase) 1.99393387E-05 7.85705407E-05 3.7904 2.7678 1.6659 1.5972 2.3037 2.1498 1.541451645 PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 2.47665084E-09 2.54948531E-08 3.7801 2.2537 2.2361 1.8917 2.5349 3.9773 2.2753115004 MB21D1 Mab-21 domain containing 1 1.08686363E-11 2.76975904E-10 3.7740 1.4668 1.2700 1.5007 1.2161 1.5758 2.1233141 ADPRH ADP-ribosylarginine hydrolase 1.72900997E-05 6.90545796E-05 3.7713 0.7352 0.8913 1.0006 0.8149 0.8388 0.84677415 VCP valosin containing protein 7.8935945E-15 1.51707465E-12 3.7699 2.4803 1.6570 1.5844 1.5911 1.9889 2.028251433 ANAPC5 anaphase promoting complex subunit 5 1.9099875E-14 2.70537144E-12 3.7682 0.5193 0.8629 0.5233 0.6798 1.1147 0.60051212 CLTB clathrin, light chain B 2.16229585E-15 6.37249513E-13 3.7663 1.8950 3.1129 1.7323 0.8118 2.7745 1.5373219699 UNC5B unc-5 homolog B (C. elegans) 0.00028133379 0.000879324505 3.7650 1.2320 1.1711 0.9557 0.6866 1.5030 1.0566286140 RNF5P1 ring finger protein 5 pseudogene 1 2.12955951E-08 1.67504569E-07 3.7631 0.0613 0.0077 0.2741 0.1812 0.0890 0.29033014 H2AFX H2A histone family, member X 5.63481103E-09 5.22334245E-08 3.7625 2.0841 1.9682 1.3820 1.6926 3.4410 1.87833767 KCNJ11 potassium inwardly-rectifying channel, subfamily J, member 11 0.00089001708 0.002501136885 3.7623 2.4635 1.3327 1.1567 2.3073 1.4442 0.99996945 MLX MLX, MAX dimerization protein 6.47245909E-16 3.47837566E-13 3.7592 1.6986 1.6577 1.5762 1.4429 2.4154 1.930584769 MPV17L2 MPV17 mitochondrial membrane protein-like 2 3.36928059E-09 3.34220928E-08 3.7584 1.6512 1.5208 2.0767 1.4522 1.5307 2.29027535 ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.1329789E-11 2.87524867E-10 3.7565 0.7814 0.8956 0.9298 0.8394 1.3741 0.972422984 PDCD11 programmed cell death 11 5.66484125E-13 2.9405676E-11 3.7562 0.4346 25.3787 3.8424 0.3318 35.4722 4.018951676 ASB2 ankyrin repeat and SOCS box containing 2 1.6454209E-05 6.60917358E-05 3.7561 0.8269 0.9560 1.7854 0.7658 0.5974 0.9849388591 RNF207 ring finger protein 207 1.65399644E-07 1.0417726E-06 3.7498 1.1442 2.2232 1.5026 0.6822 1.5577 1.65468870 IER3 immediate early response 3 1.91692208E-05 7.58138534E-05 3.7476 0.5063 0.4250 0.5732 0.4902 0.5758 0.73264860 PNP purine nucleoside phosphorylase 1.44318574E-12 5.79558019E-11 3.7464 0.9603 1.6361 1.0094 0.9907 2.6006 1.39322582 GALE UDP-galactose-4-epimerase 1.44211813E-10 2.24258575E-09 3.7457 1.2334 1.6545 1.6008 0.9253 2.0961 1.714251303 FKBP11 FK506 binding protein 11, 19 kDa 3.20548855E-09 3.19883598E-08 3.7452 1.3179 2.7844 1.7200 1.4769 3.2368 1.8113414919 C8orf82 similar to RIKEN cDNA C030006K11 gene 3.11634962E-09 3.11839761E-08 3.7448 1.9757 4.0307 1.7683 1.2896 3.6049 2.5962100289656 LOC100289656 Dexi homolog (mouse) pseudogene 0.00052614362 0.001547350202 3.7444 0.2357 0.1013 0.1291 0.2233 0.1416 0.21222017 CTTN cortactin 0.00420772305 0.010098977484 3.7410 0.8701 2.1531 1.1005 0.5265 1.8041 0.9617144097 C11orf84 hypothetical protein BC007540 5.64872111E-11 1.03969939E-09 3.7400 1.3590 1.6294 1.5869 1.0080 1.4459 1.31804830 NME1 NME/NM23 nucleoside diphosphate kinase 1 9.53733561E-08 6.3508089E-07 3.7400 0.3321 0.3321 0.3321 0.3970 0.3970 0.397079006 METRN meteorin, glial cell differentiation regulator 9.71775542E-11 1.61567632E-09 3.7389 1.0371 1.5448 1.4582 0.4258 0.6489 1.2655162466 PHOSPHO1 phosphatase, orphan 1 0.0006648042 0.001909925643 3.7375 1.7555 1.3314 1.7973 1.1274 1.4675 1.60756023 RMRP RNA component of mitochondrial RNA processing endoribonuclease 8.8530175E-12 2.34778426E-10 3.7357 0.9423 2.2836 0.7122 1.2088 3.1669 0.9917138428 PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) 1.54149878E-07 9.76300368E-07 3.7357 0.2084 0.1890 0.2296 0.3498 0.2103 0.27499875 URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 2.37685999E-12 8.36801268E-11 3.7356 4.8235 1.1690 4.7269 1.3059 1.8243 4.996926270 FBXO6 F-box protein 6 9.09793712E-07 4.77998205E-06 3.7350 1.7039 1.0691 1.3443 1.4465 1.0533 1.21257389 UROD uroporphyrinogen decarboxylase 6.25046214E-13 3.06313506E-11 3.7349 2.8851 1.6776 2.0455 1.4745 2.0439 1.42282077 ERF Ets2 repressor factor 4.53080814E-11 8.68264647E-10 3.7329 1.1651 1.3131 1.6486 1.1346 1.5783 1.88488208 CHAF1B chromatin assembly factor 1, subunit B (p60) 7.70558514E-07 4.11565191E-06 3.7326 1.0964 1.3356 0.9578 0.9232 1.5307 0.910955163 PNPO pyridoxamine 5'-phosphate oxidase 1.10869113E-12 4.66070025E-11 3.7325 1.6867 4.2878 2.3749 1.6108 3.0750 2.257726227 PHGDH phosphoglycerate dehydrogenase 2.36283851E-06 1.13465927E-05 3.7298 0.6562 1.0032 0.6878 0.7501 1.0631 1.1204100151683 RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing) 0.00049774194 0.001470926857 3.7295 2.3870 1.0927 2.3698 1.9450 0.9660 2.602993436 ARMC6 armadillo repeat containing 6 4.19615624E-12 1.33766407E-10 3.7283 0.0137 0.4339 1.7147 0.0913 0.9509 1.398124139 EML2 echinoderm microtubule associated protein like 2 1.71408477E-11 4.01021216E-10 3.7282 0.5341 1.0217 1.0056 0.6690 0.5607 0.79374744 NEFH neurofilament, heavy polypeptide 5.63677605E-06 2.50048973E-05 3.7240 0.3789 0.4401 0.6510 0.2647 0.1493 0.788856901 NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.00125258566 0.003407361201 3.7235 0.9628 1.8445 1.7282 0.7045 1.4093 1.5684399664 MEX3D mex-3 RNA binding family member D 1.41541226E-06 7.13839714E-06 3.7223 1.4126 2.4653 1.3942 0.6421 0.7510 1.681911153 FICD FIC domain containing 7.01158201E-07 3.78368655E-06 3.7221 1.3701 0.9319 1.6013 1.0272 1.1241 1.7405

10166 SLC25A15 6.51038985E-11 1.16397107E-09 3.7189 2.1349 2.3278 1.9769 1.7858 3.3755 2.031226164 MTG2 mitochondrial ribosome-associated GTPase 2 1.28261166E-12 5.20797337E-11 3.7167 3.1539 1.9251 2.1937 2.7311 1.7147 2.098764768 IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 7.46583104E-10 9.13090125E-09 3.7163 1.1831 1.7560 1.2145 1.2505 2.8218 1.99974285 MIPEP mitochondrial intermediate peptidase 2.59471337E-07 1.55495581E-06 3.7158 0.3321 0.3321 0.3321 0.3970 0.3970 0.397023630 KCNE1L KCNE1-like 0.00493569995 0.011629285557 3.7158 0.0569 0.2596 0.2437 0.2024 0.2195 0.144184303 CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 6.29631153E-07 3.43319022E-06 3.7157 1.3381 2.4833 2.1374 0.9792 1.7893 1.85724234 METTL1 methyltransferase like 1 3.67605831E-08 2.70951745E-07 3.7112 0.6482 4.6231 3.0749 0.7032 2.2889 1.720079065 ATG9A ATG9 autophagy related 9 homolog A (S. cerevisiae) 3.10198055E-15 7.76429981E-13 3.7094 1.0605 2.2526 2.2420 0.9623 1.0277 2.233823555 TSPAN15 tetraspanin 15 0.00166565306 0.004400204273 3.7058 1.1462 1.5891 2.0846 0.7177 1.5388 1.67841192 CLIC1 chloride intracellular channel 1 1.48274258E-11 3.56014093E-10 3.7056 0.7471 0.6515 0.6879 0.7660 0.9317 0.80569768 KIAA0101 KIAA0101 1.83019054E-06 9.02110645E-06 3.7051 2.5657 1.7056 1.8179 1.9148 1.7258 1.87571844 DUSP2 dual specificity phosphatase 3 5.88360532E-06 2.59611776E-05 3.7049 2.5142 3.7298 2.9659 2.0159 4.6135 3.517528976 ACAD9 acyl-CoA dehydrogenase family, member 9 1.91129627E-08 1.52153221E-07 3.7047 0.9347 1.0531 1.1458 0.8469 1.5284 1.25019123 SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 1.84908748E-07 1.15076725E-06 3.7046 0.5231 2.2680 1.0598 0.3688 1.7589 1.180956666 PANX2 pannexin 2 0.00010354221 0.000354757788 3.7019 0.3444 2.4417 0.5392 0.1274 1.5381 0.913110383 TUBB4B tubulin, beta 4B class IVb 6.86491251E-10 8.4863103E-09 3.6973 1.0705 1.4876 1.3619 1.1844 2.7016 2.438610900 RUNDC3A RUN domain containing 3A 0.00610670017 0.014005475769 3.6953 1.1915 1.8068 1.2214 0.8658 0.4629 0.7258100128569 C19orf71 chromosome 19 open reading frame 71 3.36192206E-05 0.000126475272 3.6949 0.0140 0.0130 0.1798 0.0608 0.0379 0.2692

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

scavenger receptor cysteine rich domain containing, group B (4 domains)

solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15

57524 CASKIN1 CASK interacting protein 1 2.83338477E-05 0.000108173018 3.6940 0.8126 0.8580 0.8379 0.5066 1.4657 0.85526097 RORC RAR-related orphan receptor C 0.00170804627 0.00449768287 3.6918 0.3947 0.4474 1.0493 0.3065 0.4337 0.434665078 RTN4R reticulon 4 receptor 0.00054009212 0.001583778027 3.6916 0.9427 1.4136 1.0875 0.6608 0.7030 0.715285458 DIXDC1 DIX domain containing 1 1.00104466E-06 5.21113618E-06 3.6908 0.7400 0.9777 1.1317 0.7307 0.6358 0.96126348 CCL3 chemokine (C-C motif) ligand 3 0.01601051375 0.03252296912 3.6901 0.1521 0.1648 0.9162 0.1959 0.0886 0.42954141 MARS methionyl-tRNA synthetase 6.48971324E-11 1.16141078E-09 3.6893 0.3155 0.3359 0.4142 0.3691 0.3738 0.333726472 PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 3.27922634E-11 6.70223979E-10 3.6890 1.4388 2.1877 1.8460 1.0036 2.6194 2.113329781 NCAPH2 non-SMC condensin II complex, subunit H2 4.60967662E-12 1.43001717E-10 3.6857 2.4212 2.6304 2.4222 1.3493 2.9862 2.209641 ASIC1 acid-sensing (proton-gated) ion channel 1 1.25693257E-06 6.40990008E-06 3.6854 0.3969 0.8201 0.8455 0.3545 0.6094 0.63123949 LDLR low density lipoprotein receptor 3.28927086E-10 4.58440559E-09 3.6849 0.8006 0.8334 0.9543 0.7426 1.1145 1.133027341 RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 3.16261005E-09 3.15949759E-08 3.6847 1.1849 1.5793 1.2587 1.0713 1.8662 1.3519116113 FOXP4 forkhead box P4 1.1834352E-08 9.90477115E-08 3.6808 1.1440 3.8912 1.6496 0.5338 5.3646 2.680664856 VWA1 von Willebrand factor A domain containing 1 0.0009118035 0.002557248437 3.6760 0.6837 2.9312 1.8953 0.1084 1.8172 1.349455756 INTS9 integrator complex subunit 9 9.41272263E-15 1.60737634E-12 3.6695 2.0295 3.5586 2.3569 1.7336 2.1032 0.985880723 SLC35G2 solute carrier family 35, member G2 9.02100066E-06 3.82528949E-05 3.6675 1.9751 1.4398 2.2957 1.3683 1.2312 2.33008970 HIST1H2BJ histone cluster 1, H2bj 5.31270307E-08 3.76400583E-07 3.6663 53.2279 0.8182 0.8382 58.2984 1.5004 2.32549672 SDC3 syndecan 3 0.00302390751 0.007518415831 3.6646 0.4083 0.9909 0.4976 0.1294 0.2379 0.457823729 SHPK sedoheptulokinase 2.94635597E-10 4.1733191E-09 3.6643 0.2838 3.0372 1.4011 0.3516 1.5980 0.56549833 MELK maternal embryonic leucine zipper kinase 8.3957482E-05 0.000293714553 3.6641 1.6542 1.4019 1.6667 1.1024 2.0980 2.19284669 NAGLU N-acetylglucosaminidase, alpha 4.60133503E-07 2.59012919E-06 3.6641 1.2054 2.8997 1.5362 1.0540 2.8292 1.530279080 CCDC86 coiled-coil domain containing 86 1.52174818E-08 1.24186613E-07 3.6629 2.1839 2.3737 1.7288 1.5888 3.8439 1.8357983 CDK1 cyclin-dependent kinase 1 2.81387139E-05 0.000107495417 3.6597 1.4380 3.0607 0.9301 1.0023 2.3007 1.466510036 CHAF1A chromatin assembly factor 1, subunit A (p150) 6.9785797E-09 6.24636382E-08 3.6595 1.6834 4.6448 2.5619 1.4014 4.3178 2.36546426 SRSF1 serine/arginine-rich splicing factor 1 4.78827736E-12 1.47044376E-10 3.6559 1.7718 1.7167 1.5912 2.3776 3.4638 3.1779201161 CENPV proline rich 6 9.25478918E-09 7.97658056E-08 3.6550 1.3442 2.2177 1.2824 1.0764 1.7213 2.027855027 HEATR3 HEAT repeat containing 3 5.13596867E-10 6.65091562E-09 3.6517 0.4453 1.2619 0.7561 0.4531 1.3661 0.93567036 TFR2 transferrin receptor 2 4.25005414E-05 0.000157106273 3.6499 0.5251 0.8666 0.8649 0.5101 0.7877 0.659723511 NUP188 nucleoporin 188kDa 1.9809347E-12 7.35683716E-11 3.6482 0.3225 0.3640 0.8709 0.0824 0.3759 0.6342115708 TRMT61A tRNA methyltransferase 61 homolog A (S. cerevisiae) 1.84339379E-10 2.76766569E-09 3.6476 1.3524 2.9875 2.7351 1.5809 2.9337 3.4905

92609 TIMM50 1.2690399E-10 2.01757684E-09 3.6438 1.5323 1.1528 1.1947 1.2337 1.8257 1.025311182 SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.14201956E-05 8.39171987E-05 3.6426 0.9431 1.3204 1.3359 0.5779 1.2258 1.049226073 POLDIP2 polymerase (DNA-directed), delta interacting protein 2 1.94103944E-13 1.32338331E-11 3.6420 1.1997 7.0891 2.0040 1.2950 7.2669 1.297284314 TMEM107 transmembrane protein 107 6.7203881E-07 3.63944669E-06 3.6403 1.4945 1.8627 2.1603 1.3144 1.9154 2.2590342977 NANOS3 nanos homolog 3 (Drosophila) 0.02249594619 0.04366789853 3.6403 0.0548 0.1671 0.1895 0.0869 0.0765 0.18722850 GPR27 G protein-coupled receptor 27 0.00096034699 0.002679410633 3.6353 0.3321 0.3321 0.3321 0.3970 0.3970 0.397022907 DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 5.91839883E-14 5.51739711E-12 3.6348 1.6353 2.0612 1.7300 1.3081 3.1015 2.1032699 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2.08908272E-06 1.0152053E-05 3.6348 2.7365 2.1793 2.4428 2.5933 2.6065 2.609680199 FUZ fuzzy planar cell polarity protein 4.12728654E-10 5.5167359E-09 3.6346 1.8997 2.9893 1.1011 1.7610 3.2557 1.118584879 MFSD2A major facilitator superfamily domain containing 2A 3.83374292E-05 0.000143164011 3.6319 1.5781 1.5650 1.7415 0.6835 1.6249 1.42552717 GLA galactosidase, alpha 1.28315314E-07 8.26719821E-07 3.6295 1.2133 4.4164 0.5888 1.4179 3.1102 0.5844100130899 LOC100130899 uncharacterized LOC100130899 0.00117072257 0.003207593749 3.6263 0.0992 0.1189 0.2118 0.3228 0.5491 0.22785245 PHB prohibitin 6.35066265E-11 1.1387567E-09 3.6257 2.4454 2.5273 2.2110 2.6813 4.1948 2.505010898 CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 4.76566734E-12 1.4659642E-10 3.6251 1.3798 2.8515 2.0441 1.0548 1.8342 1.72987295 TXN thioredoxin 2.98474786E-11 6.22572065E-10 3.6229 1.7187 3.6901 2.3236 1.5683 4.1363 2.887710007 GNPDA1 glucosamine-6-phosphate deaminase 1 2.82652121E-09 2.870828E-08 3.6217 1.9493 2.2719 1.7193 1.3773 1.7674 1.40088862 APLN apelin 0.01457638191 0.02999320386 3.6207 2.2483 2.4745 1.5666 1.5167 1.2496 1.07502178 FANCE Fanconi anemia, complementation group E 3.81632517E-09 3.7349702E-08 3.6194 1.9169 1.8105 1.2233 1.0827 1.7202 1.236751308 REEP2 receptor accessory protein 2 5.90497115E-05 0.000212351177 3.6191 0.6772 1.9063 1.4081 0.4734 0.8645 0.9520388507 ZNF 788 zinc finger family member 788 3.47834929E-06 1.61310655E-05 3.6176 0.9733 1.0226 1.4735 0.7518 1.2252 1.786154602 NDFIP2 Nedd4 family interacting protein 2 3.37729692E-09 3.34834342E-08 3.6175 0.4356 2.2881 0.5588 0.3843 1.0953 0.27005702 PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 2.23022566E-12 8.00539693E-11 3.6153 2.2227 2.9271 1.7718 2.1138 3.0133 2.258527043 PELP1 proline, glutamate and leucine rich protein 1 1.16716991E-12 4.84693833E-11 3.6137 0.4634 0.8200 1.0926 0.9463 0.6768 0.59187391 USF1 upstream transcription factor 1 7.37203001E-08 5.05257811E-07 3.6094 3.3742 1.6736 2.0738 3.4217 2.1895 2.239658488 PCTP phosphatidylcholine transfer protein 1.89992418E-05 7.52067039E-05 3.6092 0.7757 1.5550 1.5763 0.9235 1.4021 1.56994128 MAOA monoamine oxidase A 0.00760753101 0.01699656438 3.6092 1.6794 3.7116 3.0817 1.7024 2.7864 2.938210733 PLK4 polo-like kinase 4 1.26462916E-06 6.44195817E-06 3.6086 1.8989 1.7063 1.7281 2.2868 1.9222 2.853685395 FAM207A family with sequence similarity 207, member A 2.70635776E-10 3.89988715E-09 3.6073 4.4306 6.2888 0.9453 4.8399 2.1171 2.41758354 HIST1H3I histone cluster 1, H3i 3.70017149E-07 2.1395422E-06 3.6071 2.2641 2.2491 1.5852 2.0252 1.2361 1.4484151009 LOC151009 uncharacterized LOC151009 0.00019435215 0.000626535377 3.6026 0.3321 0.3321 0.3321 0.3970 0.3970 0.397050509 COL5A3 collagen, type V, alpha 3 0.01733405995 0.034858897578 3.6020 0.2305 0.1767 0.1473 0.1813 0.0944 0.27226449 SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 1.78854772E-13 1.24259863E-11 3.6016 1.5205 1.3415 1.9280 1.4019 1.7073 2.028029109 FHOD1 formin homology 2 domain containing 1 4.76695913E-14 4.92101002E-12 3.6011 1.5240 1.8687 1.7554 0.9618 3.8024 3.157657647 DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 3.20792363E-13 1.94090002E-11 3.5997 1.0159 1.2861 1.0129 0.8340 1.6910 0.922510419 PRMT5 protein arginine methyltransferase 5 2.91924305E-10 4.1504582E-09 3.5993 2.2990 3.2057 2.0267 2.1555 3.0464 1.86696895 TARBP2 TAR (HIV-1) RNA binding protein 2 9.29768446E-13 4.07403574E-11 3.5988 0.9916 2.0440 2.1684 1.1051 3.6180 2.8587378832 COL18A1-AS1 chromosome 21 open reading frame 123 0.01481806942 0.030425414587 3.5981 0.0162 0.0525 0.0823 0.1067 0.0865 0.0701

8541 PPFIA3 1.90761947E-06 9.36486377E-06 3.5958 3.7498 2.4303 1.0880 1.8444 0.9182 0.92386182 MRPL12 mitochondrial ribosomal protein L12 8.082817E-11 1.38675335E-09 3.5952 0.3321 0.3321 0.3321 0.3970 0.3970 0.397090313 TP53I13 tumor protein p53 inducible protein 13 9.2935158E-15 1.6019917E-12 3.5939 1.0731 2.4787 1.9813 0.8405 2.0516 2.323211284 PNKP polynucleotide kinase 3'-phosphatase 1.96311306E-14 2.73816807E-12 3.5919 1.5515 2.3322 1.7585 1.3831 3.6593 2.097579931 TNIP3 TNFAIP3 interacting protein 3 0.00016817141 0.000549406044 3.5912 0.6089 1.1144 0.8470 0.6347 0.9004 0.48323135 HLA-G major histocompatibility complex, class I, G 3.05039792E-09 3.06921095E-08 3.5911 0.3076 0.3118 0.3165 0.3782 0.3878 0.371723400 ATP13A2 ATPase type 13A2 2.01838072E-12 7.48070033E-11 3.5886 1.2124 1.9152 0.9446 0.9066 2.3092 0.9460100288198 HMGN3-AS1 HMGN3 antisense RNA 1 0.00404430383 0.009746441516 3.5858 0.8272 2.9451 1.4284 0.8804 1.9362 0.99841503 CTPS1 CTP synthase 1 6.66199183E-09 6.02613439E-08 3.5847 0.4760 1.2720 0.9819 0.5092 1.0320 0.9604146909 KIF18B kinesin family member 18B 0.00046859099 0.001391305596 3.5834 0.8489 0.8831 1.2714 0.7557 0.4473 1.412255644 OSGEP O-sialoglycoprotein endopeptidase 5.96130031E-12 1.75685289E-10 3.5821 1.0735 0.3483 0.2621 0.4330 0.4443 0.335380142 PTGES2 prostaglandin E synthase 2 7.16494153E-09 6.37690266E-08 3.5792 1.4972 1.6096 1.2801 1.5002 4.0176 2.087351540 SCLY selenocysteine lyase 0.00279413607 0.00699759516 3.5768 2.1485 1.7163 2.3051 1.7772 2.2355 3.443351603 METTL13 methyltransferase like 13 4.41919017E-13 2.43215189E-11 3.5760 2.9751 2.3757 1.7508 2.7850 2.8957 2.488951286 CEND1 cell cycle exit and neuronal differentiation 1 0.00138370609 0.003724123973 3.5755 0.1079 0.1926 0.3802 0.3022 0.1740 0.37944826 NNAT neuronatin 0.00435700734 0.010412142041 3.5752 1.3260 1.8828 0.7596 0.9322 0.9727 0.7144

4794 NFKBIE 6.83284681E-10 8.46439166E-09 3.5731 1.4409 2.5722 1.8736 1.0970 3.0070 2.411151493 RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase 9.86786515E-12 2.56831523E-10 3.5684 1.9409 2.3347 1.6315 1.6530 2.9426 1.64316714 SRC v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog 5.6920767E-05 0.000205382357 3.5675 0.5046 0.7384 0.8676 0.3122 1.2245 0.907523308 ICOSLG inducible T-cell co-stimulator ligand 4.83358817E-08 3.46350287E-07 3.5668 1.7176 2.0557 1.7925 1.2380 1.9028 2.4520112724 RDH13 retinol dehydrogenase 13 (all-trans/9-cis) 4.39653121E-09 4.21919214E-08 3.5619 0.6484 0.7175 0.7286 0.6181 0.7706 0.835654784 ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 7.52456033E-09 6.6516094E-08 3.5616 2.2311 0.6372 1.6901 5.4011 0.6162 0.823110244 RABEPK Rab9 effector protein with kelch motifs 1.0498134E-10 1.73594483E-09 3.5593 1.8447 1.4561 2.1147 1.6648 2.2338 2.26534097 MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.2971008E-12 8.15002442E-11 3.5590 0.5381 2.4478 2.4558 0.3112 1.6824 2.241429968 PSAT1 phosphoserine aminotransferase 1 3.09627514E-05 0.000117302798 3.5571 2.3087 2.5533 2.0291 1.6409 2.7429 2.6793729533 FAM72A family with sequence similarity 72, member A 2.17641192E-06 1.0528832E-05 3.5569 0.8197 1.4403 1.9086 0.6658 1.3634 1.654126775 SNORA72 small nucleolar RNA, H/ACA box 72 2.50066674E-05 9.64784263E-05 3.5567 1.0043 2.0261 0.7264 0.7497 2.0180 0.558455920 RCC2 regulator of chromosome condensation 2 1.00775493E-12 4.34285333E-11 3.5553 2.2577 2.5399 1.8504 2.0000 3.4309 3.40516838 SURF6 surfeit 6 4.25290464E-09 4.09857983E-08 3.5548 1.8044 2.9307 2.1683 1.4984 3.6691 2.25019775 EIF4A3 eukaryotic translation initiation factor 4A3 1.79522409E-12 6.77734185E-11 3.5538 2.2648 2.7127 2.0576 1.9445 3.9092 3.32686621 SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 9.67890691E-10 1.13951667E-08 3.5506 0.8070 1.4120 1.1117 0.2109 1.3897 0.672379751 SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 2.17652095E-11 4.87967986E-10 3.5490 1.2411 1.7169 1.8761 0.9039 2.0310 1.8018483 ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.0483637E-08 1.61814533E-07 3.5487 1.9121 2.5916 1.9076 1.9019 4.2702 3.9655399909 PCNXL3 pecanex-like 3 (Drosophila) 1.59157945E-16 1.41500021E-13 3.5473 0.6476 0.9559 1.2294 0.5353 1.1318 1.108229882 ANAPC2 anaphase promoting complex subunit 2 3.27552976E-10 4.56873892E-09 3.5465 1.8330 4.3356 0.8291 1.3237 4.9927 0.373651805 COQ3 coenzyme Q3 methyltransferase 5.88801593E-06 2.59743667E-05 3.5457 1.3910 1.5409 1.2132 1.4086 1.9626 1.9852138716 RPP25L ribonuclease P/MRP 25kDa subunit-like 6.63180474E-12 1.90360085E-10 3.5454 2.1308 1.3186 2.1995 1.9104 1.8381 2.3708339448 C1orf174 chromosome 1 open reading frame 174 2.4651554E-11 5.37618655E-10 3.5415 2.8458 1.3419 0.9986 4.3663 1.2915 0.6531523 ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 5.71719127E-09 5.28680076E-08 3.5406 3.1936 13.9930 3.5961 2.3659 14.1477 2.92181138 CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 2.83436053E-05 0.000108187666 3.5365 1.4662 3.4678 1.3658 1.0313 3.2951 1.2578283578 TMED8 transmembrane emp24 protein transport domain containing 8 1.28349225E-09 1.46118196E-08 3.5357 1.5642 0.5290 1.3746 1.2034 0.2598 1.0217116115 ZNF526 zinc finger protein 526 1.36301978E-12 5.52219456E-11 3.5346 1.4080 0.1960 3.7158 0.7418 0.2147 1.892922974 TPX2 TPX2, microtubule-associated 4.7587772E-07 2.67134799E-06 3.5341 1.8222 1.7517 2.1381 1.3444 1.4317 2.598154471 SMCR7L mitochondrial elongation factor 1 5.72325616E-14 5.44663211E-12 3.5335 0.5414 0.6658 0.9150 0.5976 0.7319 1.043310130 PDIA6 protein disulfide isomerase family A, member 6 3.48586474E-10 4.80344801E-09 3.5332 0.6692 0.6344 0.6430 0.5763 0.8091 0.777983879 CDCA7 cell division cycle associated 7 5.75249332E-07 3.16214073E-06 3.5330 2.8508 4.2341 1.7196 2.0518 4.8459 2.9453113000 RPUSD1 RNA pseudouridylate synthase domain containing 1 3.26153215E-13 1.96636633E-11 3.5325 0.7785 1.1057 1.5320 0.2664 1.1260 0.8945977 CD151 CD151 molecule (Raph blood group) 4.96616408E-13 2.65326755E-11 3.5313 1.7126 0.9335 1.6234 1.0759 0.4507 1.405584219 WDR24 WD repeat domain 24 2.24390931E-11 4.98186038E-10 3.5256 1.2864 2.3326 1.1805 1.4942 3.4692 1.6578140707 BRI3BP BRI3 binding protein 1.48219903E-08 1.21392831E-07 3.5250 2.8066 2.8176 2.3854 1.9423 1.5782 2.58248226 HDHD1 haloacid dehalogenase-like hydrolase domain containing 1 1.09823964E-10 1.796869E-09 3.5233 6.1223 0.1031 2.5921 4.1609 0.0652 4.9149677836 SNORA58 small nucleolar RNA, H/ACA box 58 0.01456222438 0.029970822683 3.5217 0.1937 0.5133 0.2268 0.3029 0.5094 0.185127440 CECR5 cat eye syndrome chromosome region, candidate 5 7.82966634E-10 9.50589125E-09 3.5210 2.6695 0.9523 2.6278 3.6587 0.3851 1.549479801 SHCBP1 SHC SH2-domain binding protein 1 9.18173379E-05 0.000317743636 3.5210 1.6148 1.8085 2.0105 1.1368 1.2750 2.02035209 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.80870639E-09 1.95207815E-08 3.5194 0.8301 1.7055 1.3219 0.6912 1.8870 1.187430851 TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 2.79587426E-05 0.000106986836 3.5191 4.6084 5.0547 1.7811 2.3478 0.6625 0.887555655 NLRP2 NLR family, pyrin domain containing 2 2.08073419E-09 2.19130692E-08 3.5168 0.0817 0.0931 0.4325 0.3945 1.0572 0.37078189 SYMPK symplekin 2.46690674E-13 1.60983285E-11 3.5128 1.6933 1.3930 1.0725 1.2555 2.3141 1.80869688 NUP93 nucleoporin 93kDa 1.59304037E-11 3.76559297E-10 3.5081 1.1652 1.2937 1.2059 1.2087 1.6140 1.2847126374 WTIP Wilms tumor 1 interacting protein 0.0057237447 0.01323851432 3.5073 0.4862 1.4415 0.7002 0.5379 3.2144 1.010254707 GPN2 GPN-loop GTPase 2 7.25214462E-13 3.42152182E-11 3.5053 1.4705 2.0071 1.5866 1.3401 1.8637 1.951155620 STAP2 signal transducing adaptor family member 2 3.6506215E-07 2.11289693E-06 3.5049 0.9810 1.5318 1.6846 0.6589 1.4460 1.29262997 GYS1 glycogen synthase 1 (muscle) 7.24568511E-12 2.03995621E-10 3.5044 2.8243 4.2508 2.0741 1.7352 4.0385 2.260984254 CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha 1.07269473E-06 5.55563441E-06 3.5042 0.9553 1.2454 1.2130 0.6149 0.8732 1.13541495 CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 4.05560833E-07 2.31358337E-06 3.5015 0.6016 0.6996 0.5687 1.1857 0.8389 0.897092856 IMP4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) 1.1023205E-12 4.65163977E-11 3.5010 1.1073 2.7954 1.8999 1.0277 3.0896 1.91364758 NEU1 sialidase 1 (lysosomal sialidase) 9.40275021E-12 2.46849213E-10 3.4991 0.5083 0.7291 0.5117 0.5105 0.7419 0.6522317772 HIST2H2AB histone cluster 2, H2ab 4.09861716E-07 2.33447421E-06 3.4988 3.1272 1.9247 2.0238 3.1695 1.8471 2.30597936 NELFE negative elongation factor complex member E 1.25629366E-14 2.0135963E-12 3.4976 0.3907 1.0361 0.7540 0.4251 0.8385 0.8762

1951 CELSR3 7.06787932E-11 1.24897767E-09 3.4947 0.9469 0.3869 0.5786 0.6262 0.6700 0.4773339451 KLHL17 kelch-like family member 17 2.96912489E-07 1.75629168E-06 3.4915 0.4376 1.3203 0.9716 0.3089 1.8933 1.022079622 SNRNP25 chromosome 16 open reading frame 33 1.60140548E-06 7.99696115E-06 3.4889 0.3724 0.6701 0.7236 0.1449 0.1584 1.376190378 SAMD1 sterile alpha motif domain containing 1 9.48012873E-12 2.48523547E-10 3.4887 1.0685 1.7441 1.6453 1.6530 2.0146 1.47539587 MAD2L1BP MAD2L1 binding protein 1.0209329E-13 8.07553502E-12 3.4858 1.4878 2.5998 2.0091 1.1356 2.3393 1.7653

translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon

cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)

80851 SH3BP5L SH3-binding domain protein 5-like 1.09845812E-10 1.796869E-09 3.4857 1.0999 3.9572 1.2613 1.2729 1.4727 0.733726168 SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 3.90012698E-08 2.86427332E-07 3.4840 0.3667 0.4192 0.6041 0.5354 0.3562 0.42236776 STAT5A signal transducer and activator of transcription 5A 1.2939801E-11 3.19076982E-10 3.4818 1.5579 2.0096 1.7518 1.0545 2.1970 1.4732115098 CCDC124 coiled-coil domain containing 124 1.56397013E-13 1.12952024E-11 3.4815 1.0697 1.3121 1.7209 0.7478 1.6799 1.397864852 TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 4.06427618E-13 2.2991472E-11 3.4803 2.2918 2.4464 2.1487 2.1261 2.9504 2.511023594 ORC6 origin recognition complex, subunit 6 5.27288209E-08 3.74159618E-07 3.4772 2.8564 4.2599 1.6715 1.1083 4.5842 1.761656265 CPXM1 carboxypeptidase X (M14 family), member 1 0.00111804092 0.003077096491 3.4750 1.3483 1.8920 1.8840 1.0289 1.4171 1.20908914 TIMELESS timeless circadian clock 1.16959921E-07 7.61614993E-07 3.4725 2.1930 2.1235 1.6821 2.2207 2.3717 1.6609100129405 MSTO2P misato family member 2, pseudogene 3.70023589E-11 7.37303274E-10 3.4717 1.5655 1.9257 1.5185 1.4316 2.5395 1.64262967 GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 1.39100816E-06 7.03278946E-06 3.4706 0.1885 0.2789 0.4564 0.0835 3.9542 0.68402583 B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 0.00163454116 0.004329081918 3.4704 1.1538 0.8776 1.3099 0.5456 0.7158 1.22149820 CUL7 cullin 7 3.17074214E-11 6.5390294E-10 3.4692 0.7668 0.9553 0.9712 0.9413 0.7813 1.05953487 IGFBP4 insulin-like growth factor binding protein 4 6.98078888E-06 3.03192238E-05 3.4690 1.1926 1.8360 1.1028 0.5038 1.4875 0.9933

2618 GART 2.2388123E-12 8.00539693E-11 3.4672 5.6278 5.1920 2.5669 3.9211 6.6174 2.704660 ACTB actin, beta 4.39743042E-10 5.82667503E-09 3.4661 1.6186 2.0331 1.8593 1.4619 5.0299 3.0503

9196 KCNAB3 0.00039911458 0.00120651792 3.4645 0.4137 0.3221 0.6377 0.5567 0.3617 0.30324324 MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.00165221211 0.004370182362 3.4643 1.8198 3.1552 1.8939 1.5622 2.5388 1.577965094 JMJD4 jumonji domain containing 4 1.25606781E-10 2.00640023E-09 3.4632 1.3644 5.8896 3.5316 0.5791 2.8395 3.73533145 HMBS hydroxymethylbilane synthase 8.13938559E-12 2.22564894E-10 3.4609 1.4874 0.9178 1.3563 1.1958 1.3700 1.401410573 MRPL28 mitochondrial ribosomal protein L28 4.63659144E-13 2.52142258E-11 3.4599 1.3061 1.5135 1.3487 0.8842 1.0843 0.74428607 RUVBL1 RuvB-like AAA ATPase 1 4.04311954E-12 1.29606807E-10 3.4599 1.8984 2.3944 1.5864 1.4585 3.0109 1.3688682 BSG basigin (Ok blood group) 9.56357276E-16 4.17311256E-13 3.4578 1.2069 1.9293 1.2408 0.7686 1.8157 1.557484817 TXNDC17 thioredoxin domain containing 17 7.7339769E-08 5.27492445E-07 3.4554 0.7153 1.8968 1.7326 0.0466 4.1592 2.730910252 SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00010383753 0.000355652053 3.4543 2.1767 2.4739 1.5879 1.6972 3.3396 2.7270284618 RUSC1-AS1 chromosome 1 open reading frame 104 0.00536076981 0.012495469566 3.4538 0.3321 0.3321 0.3321 0.3970 0.3970 0.39703914 LAMB3 laminin, beta 3 0.016153185 0.032787269096 3.4524 0.3731 0.7778 1.1929 0.2528 0.1341 0.608355228 PNMAL1 paraneoplastic Ma antigen family-like 1 0.0214758717 0.041986638953 3.4523 0.4393 0.9501 0.7872 0.1915 0.8257 0.58776261 RYR1 ryanodine receptor 1 (skeletal) 3.17445699E-06 1.48081894E-05 3.4517 0.1193 0.3382 0.4571 0.2169 0.2277 0.38495214 PFKP phosphofructokinase, platelet 6.58122959E-11 1.17407346E-09 3.4513 0.2469 0.4203 0.5338 0.2976 0.5522 0.589110300 KATNB1 katanin p80 (WD repeat containing) subunit B 1 1.44469616E-14 2.25619557E-12 3.4511 1.7018 1.6171 2.3675 1.7048 3.2313 3.083579998 ANKRD53 ankyrin repeat domain 53 0.01647466512 0.033332419571 3.4508 2.5299 2.5766 2.0637 1.8845 1.1781 1.6280339665 SLC35E4 solute carrier family 35, member E4 2.76550932E-08 2.10459751E-07 3.4497 1.3188 2.1501 1.5922 0.7647 1.2584 1.31977203 CCT3 chaperonin containing TCP1, subunit 3 (gamma) 4.03766748E-12 1.29606807E-10 3.4497 0.3321 0.3321 0.3321 0.3970 0.3970 0.397051293 CD320 CD320 molecule 1.10617616E-13 8.50641606E-12 3.4496 2.7195 2.3606 2.0938 2.0828 2.6111 2.08269334 B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 9.21109265E-11 1.55262993E-09 3.4480 1.3152 3.1917 1.9506 1.1413 3.5634 2.2365651746 ANKRD33B similar to ankyrin repeat domain 33 4.42014174E-07 2.50200836E-06 3.4451 1.6401 4.7486 1.9199 1.0607 3.9016 2.9160126119 JOSD2 Josephin domain containing 2 2.34717601E-12 8.27945947E-11 3.4450 0.7523 1.3297 1.5077 0.6075 1.4721 1.72545739 PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 5.32813382E-05 0.000193434654 3.4435 1.5058 1.1932 1.8770 1.1886 1.7823 1.614185456 TNKS1BP1 tankyrase 1 binding protein 1, 182kDa 5.23077329E-12 1.59294483E-10 3.4424 0.7563 1.0018 0.9641 0.6837 1.0042 0.94249110 MTMR4 myotubularin related protein 4 1.77592703E-14 2.55951107E-12 3.4406 1.3385 2.3817 1.9928 1.3076 2.7753 2.43247167 TPI1 triosephosphate isomerase 1 5.35459779E-10 6.88523652E-09 3.4385 0.9631 2.5711 1.9216 0.9822 3.7537 1.91045708 PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 7.60341187E-13 3.54808925E-11 3.4369 1.6454 1.9968 1.6250 1.4481 2.8487 1.871926608 TBL2 transducin (beta)-like 2 8.54718708E-12 2.29330694E-10 3.4358 0.9348 1.8055 2.4932 0.9925 3.4217 3.256929100 TMEM208 transmembrane protein 208 1.44011612E-10 2.24138004E-09 3.4344 0.6275 12.0229 2.3629 0.1758 32.7112 2.0897113746 ODF3 outer dense fiber of sperm tails 3 0.00129722227 0.003516742622 3.4341 0.0099 0.1025 0.1526 0.1093 0.0388 0.100856061 UBFD1 ubiquitin family domain containing 1 1.70123591E-10 2.58610504E-09 3.4326 2.2477 6.2515 3.5614 1.4589 9.5585 2.019854938 SARS2 seryl-tRNA synthetase 2, mitochondrial 6.00759032E-13 3.00238811E-11 3.4325 0.4575 1.2274 1.2498 0.3097 1.0763 0.549684662 GLIS2 GLIS family zinc finger 2 4.88016401E-05 0.000178305053 3.4325 0.0270 0.0575 0.1663 0.0785 0.0085 0.16002831 NPBWR1 neuropeptides B/W receptor 1 0.00951560636 0.02070747326 3.4320 1.5241 2.4470 2.4105 1.4202 1.9749 1.875027338 UBE2S ubiquitin-conjugating enzyme E2S 1.40645037E-09 1.56986323E-08 3.4316 1.7172 1.8972 1.6802 1.7457 2.2954 1.80448872 CDC123 cell division cycle 123 1.68818976E-13 1.18186219E-11 3.4306 2.8714 2.2978 1.8854 1.6819 2.8742 2.8929375346 TMEM110 transmembrane protein 110 4.90887919E-11 9.2660166E-10 3.4303 0.3321 0.3321 0.3321 0.3970 0.3970 0.397084988 PPP1R16A protein phosphatase 1, regulatory subunit 16A 6.48491776E-07 3.52446214E-06 3.4296 0.0667 0.0175 0.2218 0.0924 0.0905 0.2001

57596 BEGAIN 7.02042721E-05 0.0002491788 3.4287 0.8349 1.6414 1.3689 0.5785 0.8799 1.06321717 DHCR7 7-dehydrocholesterol reductase 1.20121635E-08 1.00451374E-07 3.4278 1.9373 1.8489 1.8400 1.4965 2.3827 2.4417112849 L3HYPDH L-3-hydroxyproline dehydratase (trans-) 3.99267314E-05 0.000148550702 3.4274 4.4881 4.1432 1.0952 2.8363 14.2057 0.874910155 TRIM28 tripartite motif containing 28 6.26690525E-13 3.06313506E-11 3.4267 1.0327 1.4720 1.2248 1.3619 1.5407 1.144029126 CD274 CD274 molecule 7.5380675E-08 5.1567042E-07 3.4231 3.8948 3.6828 1.7945 3.1975 4.0695 1.540655011 PIH1D1 PIH1 domain containing 1 2.54647664E-13 1.62122722E-11 3.4222 2.0486 3.5178 1.6598 1.6261 5.8483 2.05559754 STARD8 StAR-related lipid transfer (START) domain containing 8 0.01224874899 0.025784463306 3.4221 0.5407 0.8344 0.7874 0.7694 0.4516 0.764855324 ABCF3 Q9NUQ8,ATP-binding cassette, sub-family F (GCN20), member 3 3.48293974E-13 2.02320155E-11 3.4221 0.9639 1.1260 1.2566 0.9851 1.3476 1.24285315 PKM pyruvate kinase, muscle 8.38171941E-12 2.27114953E-10 3.4218 1.4050 1.5499 1.2635 1.1117 1.8912 1.69186470 SHMT1 serine hydroxymethyltransferase 1 (soluble) 3.26886053E-10 4.56291975E-09 3.4210 0.7946 1.4210 0.9042 0.7591 1.2629 1.1117122416 ANKRD9 ankyrin repeat domain 9 8.41208078E-05 0.000294229594 3.4193 0.9382 0.7656 1.5773 0.4722 0.4528 1.3146581 BAX BCL2-associated X protein 6.72563016E-12 1.92016741E-10 3.4191 1.6000 1.9797 1.8648 1.1034 1.5003 2.04042321 FLT1 fms-related tyrosine kinase 1 1.54658179E-05 6.23959869E-05 3.4168 0.3076 0.4182 0.4374 0.3430 0.4034 0.465951537 MTFP1 mitochondrial fission process 1 2.64911501E-11 5.7080931E-10 3.4142 1.1351 1.6898 1.4681 0.6942 1.6445 1.246856624 ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 2.1024868E-05 8.24922456E-05 3.4140 0.0553 0.0032 0.2988 0.0482 0.0147 0.06463268 AGFG2 ArfGAP with FG repeats 2 5.02184646E-12 1.53700467E-10 3.4134 2.0099 1.9860 1.6242 1.1866 2.4428 1.9555221927 BRAT1 chromosome 7 open reading frame 27 5.97013619E-13 3.00238811E-11 3.4128 0.8354 1.2971 0.7564 0.7752 1.1718 0.858322870 PPP6R1 protein phosphatase 6, regulatory subunit 1 7.37212202E-15 1.4691205E-12 3.4128 1.3583 1.8283 1.0340 1.3967 3.4827 1.6999100130093 LOC100130093 uncharacterized LOC100130093 3.43034253E-07 1.9974257E-06 3.4126 0.3321 0.3321 0.3321 0.3970 0.3970 0.397010430 TMEM147 transmembrane protein 147 2.53042066E-12 8.840506E-11 3.4120 0.6433 1.9761 3.1766 0.2478 1.3484 1.98288352 HIST1H3C histone cluster 1, H3c 1.25343061E-05 5.1559397E-05 3.4106 2.8011 4.3735 2.9638 2.3691 2.7714 2.217410272 FSTL3 follistatin-like 3 (secreted glycoprotein) 4.0437441E-07 2.30753567E-06 3.4102 1.0776 1.9275 1.1277 0.7474 1.9197 1.3534283358 B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3 0.01107467747 0.023612194483 3.4085 0.9264 0.8590 0.9681 0.6048 0.9186 0.7475

1622 DBI 1.57943494E-11 3.74311742E-10 3.4068 1.0475 2.3899 2.5765 0.6707 1.4708 1.23295364 PLXNB1 plexin B1 0.000161835 0.000530317274 3.4051 0.2850 0.4138 0.3847 0.3360 0.3286 0.421210994 ILVBL ilvB (bacterial acetolactate synthase)-like 1.65829574E-11 3.89505467E-10 3.4033 1.4577 1.8417 1.5547 1.1003 2.0929 2.36695091 PC pyruvate carboxylase 8.46302933E-07 4.47961969E-06 3.4031 1.1295 0.6756 1.1093 0.6025 0.6694 1.01913557 IL1RN interleukin 1 receptor antagonist 0.00788501987 0.017548731182 3.4030 0.2277 0.6011 0.9040 0.3251 0.3368 0.494910525 HYOU1 hypoxia up-regulated 1 1.50829268E-08 1.23270364E-07 3.4004 1.3164 2.4533 1.6977 1.1551 2.3858 1.646211065 UBE2C ubiquitin-conjugating enzyme E2C 2.38899839E-05 9.24434107E-05 3.3988 0.8714 1.6513 1.8457 0.6723 1.6806 1.9974161742 SPRED1 sprouty-related, EVH1 domain containing 1 0.00739494097 0.01656126731 3.3972 2.3079 3.8982 2.5547 1.4471 3.6821 2.56575028 P2RY1 purinergic receptor P2Y, G-protein coupled, 1 0.004970646 0.01170407779 3.3957 0.9305 2.3357 1.4812 0.9721 1.4084 1.700254962 TIPIN TIMELESS interacting protein 2.88765827E-07 1.71031741E-06 3.3953 1.1529 0.6015 1.2761 0.8576 0.7941 1.305054920 DUS2 dihydrouridine synthase 2 2.91976647E-08 2.20272391E-07 3.3941 1.4169 3.9932 2.1087 0.9023 6.5404 1.64115361 PLXNA1 plexin A1 2.8995412E-09 2.93520314E-08 3.3934 0.0368 0.0441 0.1414 0.1527 0.0763 0.16365763 PTMS parathymosin 4.82009454E-07 2.69748139E-06 3.3933 0.6992 1.7161 1.5866 0.3211 1.1080 1.134479913 ACTR5 ARP5 actin-related protein 5 homolog (yeast) 1.17225855E-10 1.90183958E-09 3.3933 1.9860 1.7121 1.7077 1.9668 2.0512 1.65558663 EIF3C eukaryotic translation initiation factor 3, subunit C 8.70487234E-05 0.000303309358 3.3931 0.5935 0.6386 0.7465 0.6668 0.4271 0.726910615 SPAG5 sperm associated antigen 5 3.96209465E-07 2.2673158E-06 3.3924 4.2847 0.6391 1.7641 0.3648 0.7158 0.589555815 TSNAXIP1 translin-associated factor X interacting protein 1 0.01552460516 0.03169447883 3.3921 0.4474 0.6856 0.2528 0.3286 0.2890 0.24063936 LCP1 lymphocyte cytosolic protein 1 (L-plastin) 2.65695166E-12 9.1853835E-11 3.3916 1.4051 1.5164 1.1686 1.0670 1.4996 0.851523597 ACOT9 acyl-CoA thioesterase 9 5.59288997E-13 2.92781141E-11 3.3914 0.9792 1.3717 0.7480 0.8707 1.6504 1.11595585 PKN1 protein kinase N1 1.626259E-16 1.41500021E-13 3.3888 1.9371 1.5078 2.1740 1.3591 1.1022 1.8396677803 SNORA15 small nucleolar RNA, H/ACA box 15 2.88266783E-05 0.000109870894 3.3832 0.1947 0.2396 0.3783 0.2744 0.1282 0.260656935 SMCO4 single-pass membrane protein with coiled-coil domains 4 2.23665446E-07 1.3613641E-06 3.3828 1.4718 2.5262 2.5090 0.9809 1.9184 2.8005125950 RAVER1 ribonucleoprotein, PTB-binding 1 1.75224316E-14 2.55951107E-12 3.3825 0.8444 1.0260 1.1340 1.2708 2.2396 1.511257192 MCOLN1 mucolipin 1 2.42823078E-08 1.87525921E-07 3.3822 1.2478 1.1071 2.1619 0.9127 0.8841 1.541310908 PNPLA6 patatin-like phospholipase domain containing 6 2.49964755E-13 1.61813867E-11 3.3821 2.0628 3.2907 1.9725 1.7853 3.4248 2.71435331 PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.28996201E-08 1.78531423E-07 3.3811 1.6250 1.1912 2.4980 0.7943 0.9853 2.1807488 ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 2.96436763E-08 2.22992694E-07 3.3791 0.8633 0.9258 0.6417 0.7824 1.3185 1.0461

7532 YWHAG 1.7448684E-11 4.07180528E-10 3.3771 1.5446 1.7551 1.8099 1.6754 3.4210 3.19603554 IL1R1 interleukin 1 receptor, type I 0.00034973631 0.001069368104 3.3739 0.3422 0.2254 0.5589 0.2070 0.2589 0.477228992 MACROD1 MACRO domain containing 1 4.87639342E-11 9.21421515E-10 3.3735 1.2009 1.4178 1.6773 1.1254 1.9146 2.231227037 TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) 7.18815792E-13 3.40264304E-11 3.3731 12.0135 4.2318 1.5611 12.4822 3.5078 0.99929603 NFE2L3 nuclear factor, erythroid 2-like 3 2.91210793E-11 6.12313418E-10 3.3723 1.2771 1.6795 2.0988 0.8906 1.9030 2.21123171 FOXA3 forkhead box A3 0.00894704117 0.019604664538 3.3714 0.3565 0.2225 0.7009 0.1532 0.1187 0.677825979 DHRS7B dehydrogenase/reductase (SDR family) member 7B 8.65518427E-08 5.83139849E-07 3.3711 1.4312 1.6880 1.5040 1.4857 1.8489 1.90707372 UMPS uridine monophosphate synthetase 4.38959294E-12 1.38049298E-10 3.3708 2.8131 1.4610 1.1856 3.8851 2.1196 1.627156926 NCLN nicalin 2.10488116E-11 4.74901994E-10 3.3702 0.6857 0.5604 0.6198 0.6751 0.7280 0.844823543 RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.00020355517 0.000653591485 3.3701 0.5048 0.5878 0.6278 0.4716 0.4874 0.48066351 CCL4 chemokine (C-C motif) ligand 4 0.00768718591 0.017154404126 3.3701 0.3467 0.1770 0.5350 0.3171 0.1804 0.329384818 IL17RC interleukin 17 receptor C 0.00060993892 0.001767894019 3.3698 0.5672 0.6985 0.7555 0.4238 0.2475 0.383651078 THAP4 THAP domain containing 4 3.35522321E-13 1.99261232E-11 3.3684 2.5103 1.7044 2.0394 1.5658 1.3463 2.32881890 TYMP enoyl CoA hydratase, short chain, 1, mitochondrial 0.00028347101 0.000885096084 3.3647 0.7369 3.6755 1.3561 0.5202 2.7580 2.15303902 LAG3 lymphocyte-activation gene 3 1.39565416E-06 7.05237635E-06 3.3643 0.9969 1.9876 2.1846 0.4594 1.2083 1.892893185 IGSF8 immunoglobulin superfamily, member 8 1.46824222E-15 5.36233287E-13 3.3633 1.5977 1.9311 2.2317 1.4845 2.2504 2.0521

518 ATP5G3 2.96705595E-12 1.00396382E-10 3.3628 1.1342 2.2209 1.8148 1.2135 3.3189 2.59284049 LTA lymphotoxin alpha 6.64440161E-06 2.90168514E-05 3.3617 0.4772 0.6885 0.6293 0.4690 0.6393 0.58289816 URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 1.76870496E-09 1.9134267E-08 3.3612 1.6228 4.3128 1.1732 0.4101 5.8450 0.772057130 ATP13A1 ATPase type 13A1 3.74374923E-14 4.24880658E-12 3.3600 0.4248 0.4860 0.8568 0.4533 0.5886 0.722355355 HJURP Holliday junction recognition protein 6.72479866E-05 0.000239523433 3.3579 1.8718 2.2851 1.8909 1.4989 2.6091 2.34567384 UQCRC1 ubiquinol-cytochrome c reductase core protein I 7.14207195E-13 3.3935069E-11 3.3570 1.2638 2.6741 1.8296 1.0584 4.8862 2.3886203069 R3HCC1 R3H domain and coiled-coil containing 1 6.13937533E-13 3.04007225E-11 3.3568 1.5005 2.6026 2.0628 1.1735 2.1054 2.05918629 JRK jerky homolog (mouse) 7.40764271E-09 6.56413422E-08 3.3541 6.1282 3.5853 2.1104 5.9873 2.5835 1.5615373863 DND1 DND microRNA-mediated repression inhibitor 1 1.29711887E-05 5.31530748E-05 3.3538 0.1400 0.2350 0.3180 0.2532 0.1012 0.360626301 GBGT1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 0.00290654743 0.007254259605 3.3530 0.3321 0.3321 0.3321 0.3970 0.3970 0.397010953 TOMM34 translocase of outer mitochondrial membrane 34 2.28989856E-11 5.04981707E-10 3.3515 2.1757 2.7663 1.5500 1.5445 2.8389 1.166510105 PPIF peptidylprolyl isomerase F 3.29020437E-07 1.92502767E-06 3.3514 1.1494 2.1976 1.2201 0.8519 1.4327 1.58092687 GGT5 gamma-glutamyltransferase 5 0.01583751768 0.032210944239 3.3505 0.3305 0.4144 0.4024 0.1921 0.0944 0.3559439 ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 9.02367291E-14 7.40214508E-12 3.3496 2.3308 2.8011 2.3854 1.7339 3.7144 2.673923644 EDC4 enhancer of mRNA decapping 4 1.18627816E-15 4.71210315E-13 3.3491 1.1947 1.3522 1.0994 1.0914 1.9601 0.9798116238 TLCD1 TLC domain containing 1 6.19437594E-05 0.000222059324 3.3467 1.6118 3.8862 1.6555 1.0138 3.8028 2.37556839 SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 1.06371337E-08 9.01492145E-08 3.3462 1.0708 1.0755 1.3497 0.7545 1.0911 1.25448974 P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.01535147095 0.03137256203 3.3449 0.4231 0.8356 1.3644 0.3755 0.8068 1.3192

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

potassium voltage-gated channel, shaker-related subfamily, beta member 3

likely ortholog of rat brain-enriched guanylate kinase-associated protein

diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)

80789 INTS5 integrator complex subunit 5 3.11467264E-10 4.37442725E-09 3.3436 2.5356 3.0964 1.7219 2.0613 3.1470 2.157451150 SDF4 stromal cell derived factor 4 3.92102803E-12 1.26358067E-10 3.3412 0.8939 1.3086 1.0169 0.7002 2.8375 1.2570

4241 MFI2 0.00019604658 0.000631643231 3.3408 1.2010 3.0126 1.3279 0.7705 1.8125 1.038711194 ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 3.54872293E-10 4.88270071E-09 3.3400 2.0155 2.5426 1.7857 1.9965 3.2542 1.85892902 GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.02134391775 0.041764410483 3.3390 0.2143 0.2609 0.3414 0.1435 0.1139 0.4680390748 PABPN1L poly(A) binding protein, nuclear 1-like (cytoplasmic) 0.00125795156 0.003421448473 3.3388 0.0475 0.0197 0.0745 0.0246 0.0848 0.360551236 FAM203A family with sequence similarity 203, member A 1.86306371E-13 1.28460001E-11 3.3375 1.7557 1.6559 1.8849 1.8120 1.9892 2.28491727 CYB5R3 cytochrome b5 reductase 3 2.21662853E-12 7.97761619E-11 3.3368 0.7880 1.5501 1.0476 0.6175 1.9044 1.139123276 KLHL18 kelch-like family member 18 8.41953172E-12 2.27114953E-10 3.3357 0.6055 0.5525 0.2409 0.2497 0.2619 0.3755126432 RINL FLJ45909 protein 1.566324E-12 6.12845229E-11 3.3344 1.8411 1.8538 2.3502 0.9546 1.6220 1.912391056 AP5B1 DKFZp761E198 protein 1.56604549E-06 7.83108461E-06 3.3319 1.2079 7.0078 1.8618 0.9343 6.1705 2.9153284615 ANKRD34A ankyrin repeat domain 34 7.2201049E-08 4.96148013E-07 3.3319 2.6698 36.5850 3.9281 0.6357 6.6177 1.16742101 ESRRA estrogen-related receptor alpha 1.95115358E-14 2.73816807E-12 3.3307 0.7832 0.9412 1.1938 0.6532 1.3133 1.754910985 GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 4.35807174E-17 8.75611785E-14 3.3300 2.5704 2.0068 2.8891 1.7132 2.1689 2.28221020 CDK5 cyclin-dependent kinase 5 1.43579518E-11 3.479423E-10 3.3299 0.4669 0.8915 0.6462 0.3209 0.3154 0.42514191 MDH2 malate dehydrogenase 2, NAD (mitochondrial) 5.41609368E-14 5.32058407E-12 3.3290 2.0117 1.2606 3.2560 2.9051 0.5335 1.677579888 LPCAT1 lysophosphatidylcholine acyltransferase 1 2.0729522E-14 2.86946838E-12 3.3275 0.4319 1.2770 0.7334 0.3509 1.1829 0.698884667 HES7 hairy and enhancer of split 7 (Drosophila) 0.00482418079 0.01140328996 3.3272 2.0397 2.8934 3.0931 1.1943 2.8217 2.281190161 HS6ST2 heparan sulfate 6-O-sulfotransferase 2 0.00362006331 0.008819439578 3.3223 0.2256 1.0962 0.4953 0.3110 1.0694 0.4860163702 IFNLR1 interferon, lambda receptor 1 8.38840029E-08 5.6704717E-07 3.3220 2.5824 2.7557 1.9457 1.9053 2.1347 1.60567272 TTK TTK protein kinase 9.18832706E-05 0.000317911593 3.3194 1.9084 1.4966 2.3214 1.6759 1.2964 2.35343972 LHB luteinizing hormone beta polypeptide 0.01497464059 0.030719280655 3.3142 0.9630 1.1799 0.9616 0.7497 1.2008 0.89305425 POLD2 polymerase (DNA directed), delta 2, accessory subunit 1.78989575E-08 1.43317156E-07 3.3133 1.6380 2.7707 2.0500 1.3705 3.8326 2.080280727 TTYH3 tweety family member 3 1.77631823E-07 1.10812177E-06 3.3119 0.8718 1.2820 1.1648 0.4187 1.9172 1.481623587 ELP5 elongator acetyltransferase complex subunit 5 2.98337984E-11 6.22572065E-10 3.3098 1.6270 3.5158 2.4522 0.7579 1.2578 1.133710785 WDR4 WD repeat domain 4 2.01815556E-06 9.8387776E-06 3.3085 1.5764 2.2839 2.5067 0.8057 2.4050 1.47767086 TKT transketolase 1.59139963E-09 1.74958208E-08 3.3084 0.5005 0.5537 0.5656 0.8571 0.9487 0.876992170 MTG1 mitochondrial ribosome-associated GTPase 1 1.23314065E-12 5.07476261E-11 3.3073 0.7331 1.5404 1.0697 0.8167 1.8749 0.9725200172 SLFNL1 schlafen-like 1 0.00093984717 0.002627028845 3.3059 0.0455 0.1273 0.2364 0.0261 0.0374 0.152855159 RFWD3 ring finger and WD repeat domain 3 2.42096912E-10 3.5291625E-09 3.3057 0.8302 1.2330 1.3953 0.7952 1.9689 1.53444839 NOP2 NOP2 nucleolar protein 2.16264251E-12 7.84043727E-11 3.3034 1.6648 2.8834 2.0310 1.6738 4.5959 2.4101

80270 HSD3B7 0.00819090564 0.018156524074 3.3016 0.2081 0.1163 0.3387 0.0591 0.0525 0.334356949 XAB2 XPA binding protein 2 1.07916523E-14 1.77644208E-12 3.2996 1.1785 0.8392 3.6379 0.6053 0.4849 1.7740

5553 PRG2 0.00826133251 0.018283801786 3.2989 0.5309 1.4062 0.9743 0.3819 1.9763 0.638293010 B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 0.01281932691 0.026827939682 3.2976 0.2148 0.4140 0.5971 0.2024 0.2920 0.30998565 YARS tyrosyl-tRNA synthetase 1.87291845E-10 2.8073803E-09 3.2962 1.1571 2.5644 1.2858 0.5596 2.0742 0.72946396 SEC13 SEC13 homolog (S. cerevisiae) 1.70520547E-10 2.58998457E-09 3.2960 0.8458 0.8334 0.8972 0.9568 1.3327 0.8952388341 FAM211A family with sequence similarity 211, member A 1.06543766E-07 7.00780308E-07 3.2959 0.3650 0.6047 0.7999 0.2305 0.2077 0.77894861 NPAS1 neuronal PAS domain protein 1 0.01280004107 0.026790647251 3.2924 1.6052 1.3920 1.3186 0.8204 0.8727 0.854784287 ZDHHC16 zinc finger, DHHC-type containing 16 6.09864675E-11 1.10990511E-09 3.2910 0.6586 2.2414 3.6147 0.3891 0.6643 2.47859562 MINPP1 multiple inositol-polyphosphate phosphatase 1 3.50602241E-09 3.46468586E-08 3.2897 1.0905 1.4095 0.9273 1.0647 2.7689 2.00603159 HMGA1 high mobility group AT-hook 1 5.90284893E-12 1.74808518E-10 3.2895 1.6026 2.6142 1.8164 1.3770 3.1338 1.503481624 DIAPH3 diaphanous-related formin 3 0.0001534736 0.000505729401 3.2894 0.7693 0.6340 0.6388 0.6782 0.7396 0.867723286 WWC1 WW and C2 domain containing 1 0.00072599657 0.002072720216 3.2880 0.1983 1.1168 0.4727 0.2397 1.3609 0.4703112464 PRKCDBP protein kinase C, delta binding protein 0.0069765508 0.015741607327 3.2872 0.2992 1.1685 1.7720 0.3328 0.6757 1.446193082 NEURL3 neuralized homolog 3 (Drosophila) pseudogene 0.00245884797 0.006246591925 3.2855 0.4069 0.9146 0.6379 0.1984 0.5357 0.46367922 SLC39A7 solute carrier family 39 (zinc transporter), member 7 5.94334049E-11 1.08488229E-09 3.2854 0.3321 0.3321 0.3321 0.3970 0.3970 0.397084872 ZC3H10 zinc finger CCCH-type containing 10 4.91486038E-08 3.51622274E-07 3.2852 2.6129 2.5144 2.1502 1.7090 1.9530 2.47169399 STOML1 stomatin (EPB72)-like 1 1.4155037E-08 1.16695857E-07 3.2815 1.1002 4.2828 1.1353 0.7188 3.1276 1.04773560 IL2RB interleukin 2 receptor, beta 2.27168299E-09 2.36110304E-08 3.2813 1.2244 2.1909 2.5953 0.6745 2.2926 2.8701390637 GDPGP1 GDP-D-glucose phosphorylase 1 4.64641458E-06 2.09421034E-05 3.2813 1.0231 4.2358 1.1696 0.5091 5.3088 0.0908718 C3 complement component 3 0.01621482845 0.032894120733 3.2780 0.0912 0.0594 0.2779 0.3512 0.2577 0.23142648 KAT2A K(lysine) acetyltransferase 2A 1.44213974E-07 9.19747901E-07 3.2770 1.3478 1.5613 1.0825 0.9613 0.8711 0.825890379 DCAF15 hypothetical protein BC002926 6.69528005E-14 6.08637598E-12 3.2759 0.8882 1.5257 1.2843 0.6927 1.3247 1.3192100158262 SCARNA9L small Cajal body-specific RNA 9-like 8.92255427E-05 0.000309948501 3.2749 0.4468 0.7226 0.7406 0.5086 0.3689 0.379557530 CGN cingulin 0.00068865965 0.001971668617 3.2748 2.3113 3.2374 2.1191 1.7752 3.0496 1.873910749 KIF1C kinesin family member 1C 1.72695607E-12 6.57394609E-11 3.2741 0.7090 5.9832 3.0033 0.2787 2.4664 1.8228257 ALX3 ALX homeobox 3 0.00295735346 0.007367979616 3.2741 0.4516 0.6779 0.5140 0.3266 2.0825 0.3340

4356 MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.01363084085 0.028305798841 3.2737 0.8823 0.6528 0.9642 0.6879 0.7485 0.92417296 TXNRD1 thioredoxin reductase 1 8.20166002E-11 1.40298837E-09 3.2733 1.0328 1.3740 1.0100 0.9155 1.6918 0.92154810 NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 6.96545233E-05 0.000247275588 3.2731 0.1363 0.2949 0.6690 0.4711 0.1394 0.509222948 CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 4.37076915E-11 8.43323062E-10 3.2728 6.4429 1.1910 2.4101 5.7740 3.7953 2.3512128178 EDARADD EDAR-associated death domain 0.00366641774 0.008922853613 3.2716 1.2943 1.8724 1.2921 1.0775 0.8030 1.110180045 GPR157 G protein-coupled receptor 157 0.00013512343 0.000450954379 3.2710 1.0653 1.2728 1.8615 0.7369 1.1089 1.8323146956 EME1 essential meiotic structure-specific endonuclease 1 1.02780367E-05 4.30932276E-05 3.2692 0.2042 0.1763 0.2640 0.1175 2.9641 0.25951237 CCR8 chemokine (C-C motif) receptor 8 0.00257159416 0.006502652701 3.2687 0.3130 0.2038 0.7626 0.2870 0.1357 0.369494081 SFXN1 sideroflexin 1 2.93901138E-11 6.17259953E-10 3.2675 2.2007 2.8764 1.8647 2.1092 4.2944 2.234650512 PODXL2 podocalyxin-like 2 4.74422865E-08 3.40481327E-07 3.2665 0.5423 0.9532 0.9803 0.4413 1.3139 0.53289817 KEAP1 kelch-like ECH-associated protein 1 2.3482151E-14 3.06899214E-12 3.2660 0.6016 0.8983 1.0233 0.6295 1.0040 1.4744100128927 ZBTB42 zinc finger and BTB domain containing 42 7.60792248E-08 5.2025434E-07 3.2659 0.8117 1.5645 1.6612 0.6150 1.1728 1.44832021 ENDOG endonuclease G 4.65313873E-10 6.1167015E-09 3.2658 1.5462 3.2009 1.9535 1.5225 3.9237 2.3727200081 TXLNA taxilin alpha 4.21208693E-13 2.35361628E-11 3.2654 2.0393 1.5969 2.0689 1.4544 1.3651 2.22705499 PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.35394656E-16 1.3744062E-13 3.2644 1.7006 1.7485 1.9522 1.0440 1.6034 1.776083854 ANGPTL6 angiopoietin-like 6 0.00011365692 0.000385939277 3.2616 0.5104 0.6742 1.8367 0.4253 0.4969 0.83651642 DDB1 damage-specific DNA binding protein 1, 127kDa 2.61382252E-13 1.64122904E-11 3.2613 0.1462 0.7807 0.9106 0.1535 0.2368 0.211910469 TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 8.28438132E-09 7.22540408E-08 3.2612 1.9785 1.4986 1.6687 1.7831 2.6735 2.300051225 ABI3 ABI family, member 3 1.13254111E-07 7.40386085E-07 3.2597 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702710 GK glycerol kinase 6.17429318E-09 5.63671439E-08 3.2589 1.4211 1.4522 1.7427 1.6138 3.3712 3.18963703 STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 2.13170108E-10 3.15643777E-09 3.2561 1.0565 1.2908 0.9133 1.0763 1.8919 1.2719595 CCND1 cyclin D1 0.00026358957 0.000830111791 3.2556 1.2691 2.1484 1.0622 1.0453 1.0277 0.4433284207 METRNL meteorin, glial cell differentiation regulator-like 3.77226784E-06 1.73357339E-05 3.2532 0.9713 2.0092 1.7267 0.6055 1.6033 1.56479704 DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 1.53840302E-11 3.66967362E-10 3.2524 0.6084 0.5010 0.6799 0.5574 0.7298 0.601623139 MAST2 microtubule associated serine/threonine kinase 2 1.08290555E-10 1.77643295E-09 3.2519 0.4033 0.6053 0.6152 0.3035 0.4777 0.5460

6541 SLC7A1 9.49300653E-09 8.15880599E-08 3.2518 1.4657 2.2922 2.1867 0.9967 3.9078 2.849310078 TSSC4 tumor suppressing subtransferable candidate 4 2.65929722E-12 9.1853835E-11 3.2477 1.3918 1.9301 1.8364 1.6658 2.6562 2.6349100131454 DBIL5P diazepam binding inhibitor-like 5, pseudogene 0.00096654187 0.002694637319 3.2445 0.9957 1.1539 3.3135 1.7580 0.6196 4.55373654 IRAK1 interleukin-1 receptor-associated kinase 1 3.09542099E-14 3.77063549E-12 3.2417 0.7692 1.5821 2.9688 0.4289 0.9295 2.97504597 MVD mevalonate (diphospho) decarboxylase 1.01577968E-11 2.63267039E-10 3.2416 2.1269 1.6398 2.1662 0.9512 1.3150 1.0073677831 SNORA51 small nucleolar RNA, H/ACA box 51 0.00374554412 0.009100875283 3.2413 0.2074 1.3281 1.1460 0.4369 0.7466 0.877610560 SLC19A2 solute carrier family 19 (thiamine transporter), member 2 3.23269342E-07 1.89410703E-06 3.2406 2.3627 2.9682 2.5346 2.0471 3.5689 2.93861545 CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.02196978327 0.042782892448 3.2397 0.7799 1.1176 1.7160 0.6603 0.5971 1.97815699 PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 1.77831121E-10 2.68317939E-09 3.2320 1.7858 1.3151 1.7570 1.7127 2.4515 2.458726284 ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 5.4279892E-11 1.00792905E-09 3.2304 1.0050 0.7455 1.3262 1.0805 1.0897 1.6910894 CCND2 cyclin D2 9.35282584E-10 1.10795067E-08 3.2297 2.5309 1.7999 2.3406 2.2316 3.2757 3.126384752 B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 3.03927327E-06 1.42393849E-05 3.2297 0.9390 0.7106 1.2146 0.5597 0.7232 1.247292162 TMEM88 transmembrane protein 88 0.0010016499 0.002781904084 3.2257 0.1518 0.7062 1.6183 0.6692 0.3231 0.927193474 ZNF670 zinc finger protein 670 1.69349609E-05 6.77992123E-05 3.2253 0.3321 0.3321 0.3321 0.3970 0.3970 0.397029088 MRPL15 mitochondrial ribosomal protein L15 1.30318045E-13 9.75889881E-12 3.2250 2.0193 2.1891 1.6444 1.9506 2.2213 1.96845932 RBBP8 retinoblastoma binding protein 8 3.58359097E-09 3.5298854E-08 3.2243 0.4618 0.8634 0.8238 0.3300 0.5099 0.55203978 LIG1 ligase I, DNA, ATP-dependent 7.32588735E-08 5.0266096E-07 3.2242 0.5533 0.9240 0.6426 0.7584 1.4400 1.054251400 PPME1 protein phosphatase methylesterase 1 9.12415056E-10 1.08468757E-08 3.2240 1.0925 3.5988 1.9626 0.8732 1.2768 1.069255215 FANCI Fanconi anemia, complementation group I 6.90403071E-07 3.72895209E-06 3.2234 0.6657 1.0672 0.7928 0.7697 1.2682 1.0585221504 ZBTB9 zinc finger and BTB domain containing 9 2.04352336E-09 2.15709179E-08 3.2232 1.4371 1.5324 1.1746 1.3003 2.4177 1.2613

2793 GNGT2 7.32962236E-05 0.000259096266 3.2218 2.1643 2.5090 2.7368 1.6202 2.4569 1.21402153 F5 coagulation factor V (proaccelerin, labile factor) 8.66255136E-07 4.57462828E-06 3.2212 1.4465 2.2869 2.0759 1.2632 3.6223 1.616325940 FAM98A family with sequence similarity 98, member A 3.73492404E-10 5.10048819E-09 3.2209 0.8991 0.8487 0.6123 0.9460 1.2802 0.937479947 DHDDS dehydrodolichyl diphosphate synthase 1.10799421E-13 8.50641606E-12 3.2188 2.4794 2.4520 2.4567 1.9014 2.3433 2.624479050 NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) 1.95239729E-12 7.28171067E-11 3.2180 2.0913 2.2334 0.5991 1.1847 2.4319 0.43859020 MAP3K14 mitogen-activated protein kinase kinase kinase 14 1.32462988E-09 1.49960577E-08 3.2177 0.5376 0.8357 0.5571 0.4368 1.1730 0.74653995 FADS3 fatty acid desaturase 3 5.35736708E-07 2.96187023E-06 3.2170 0.7202 1.7136 1.3220 0.4523 2.8476 1.501010381 TUBB3 tubulin, beta 3 class III 1.30338039E-05 5.33976826E-05 3.2167 0.1346 0.3466 0.5644 0.1062 0.3084 0.412651654 CDK5RAP1 CDK5 regulatory subunit associated protein 1 1.25045075E-10 2.00348165E-09 3.2156 1.1020 1.9951 0.9348 1.0675 3.7364 1.0173

8884 SLC5A6 2.17190891E-10 3.19939373E-09 3.2151 0.2915 33.5981 0.4515 0.1439 9.8915 0.40239970 NR1I3 nuclear receptor subfamily 1, group I, member 3 0.00186752082 0.004871978921 3.2090 0.0875 0.0468 0.2320 0.4040 0.5495 0.209983706 FERMT3 fermitin family member 3 4.67118888E-17 8.75611785E-14 3.2083 1.4900 1.9425 2.6732 1.3038 3.1101 2.6923578 BAK1 BCL2-antagonist/killer 1 4.81516634E-14 4.94284941E-12 3.2069 0.6289 0.9653 0.7811 0.6786 1.2331 0.954123549 DNPEP aspartyl aminopeptidase 1.26981905E-10 2.01757684E-09 3.2064 0.7602 0.7008 0.9024 0.8048 1.0089 0.9156949 SCARB1 scavenger receptor class B, member 1 8.30913528E-07 4.40659122E-06 3.2024 0.8661 1.0563 0.9948 0.6069 0.7608 0.8376677807 SNORA22 small nucleolar RNA, H/ACA box 22 2.02250413E-07 1.24806469E-06 3.2021 0.2889 0.4543 0.7984 0.3765 0.6024 0.3104401541 CENPP centromere protein P 1.93875251E-05 7.65317393E-05 3.2015 0.1788 0.1887 0.2141 0.2483 0.2582 0.3027119559 SFXN4 sideroflexin 4 1.52364708E-08 1.24260991E-07 3.2004 1.2732 1.2514 1.5363 1.3340 1.2419 1.52978013 NR4A3 nuclear receptor subfamily 4, group A, member 3 0.00098884976 0.002750771834 3.1997 2.9340 3.6275 2.3220 2.0588 3.9496 3.6000

54584 GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 2.22057149E-10 3.26085935E-09 3.1997 0.3321 0.3321 0.3321 0.3970 0.3970 0.39705704 PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.27481853E-13 1.51147215E-11 3.1984 2.5024 1.5469 2.5143 1.9857 2.1501 3.1551396 ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 2.15960309E-12 7.84043727E-11 3.1954 1.5740 2.2145 1.9956 1.3315 2.5864 3.255179709 COLGALT1 glycosyltransferase 25 domain containing 1 1.76007559E-10 2.66005799E-09 3.1948 0.6021 1.0017 1.1927 0.5627 1.1920 1.133211047 ADRM1 adhesion regulating molecule 1 5.25823897E-14 5.25019358E-12 3.1931 0.9805 1.9256 1.7289 0.9439 2.2238 3.46835600 MAPK11 mitogen-activated protein kinase 11 3.98592275E-07 2.2780976E-06 3.1931 1.1513 1.2415 1.4783 0.5605 0.7146 1.20917408 VASP vasodilator-stimulated phosphoprotein 1.1521742E-13 8.77188624E-12 3.1928 0.7977 1.6573 1.4826 0.9498 2.1549 2.10521947 EFNB1 ephrin-B1 8.40859484E-07 4.45338681E-06 3.1902 1.7826 4.6403 3.1683 1.8371 3.7414 3.4350140838 NANP N-acetylneuraminic acid phosphatase 2.13853503E-06 1.03620557E-05 3.1895 1.7977 2.1382 1.6598 1.5603 3.5257 2.10584641 MYO1C myosin IC 2.29073706E-11 5.04981707E-10 3.1887 0.8604 1.6466 1.3661 0.5869 1.1232 1.208879077 DCTPP1 XTP3-transactivated protein A 2.71494673E-09 2.7667321E-08 3.1883 1.2798 2.9895 2.4490 1.0059 3.7214 2.09524001 LMNB1 lamin B1 6.82535339E-07 3.69082146E-06 3.1871 2.3997 2.0070 1.8429 2.4249 2.1276 2.627910549 PRDX4 peroxiredoxin 4 1.83904787E-08 1.46995113E-07 3.1859 2.0203 1.3418 1.6738 1.3035 1.6935 1.335310650 SLMO1 slowmo homolog 1 (Drosophila) 0.00549490908 0.01276741845 3.1806 1.5641 1.3649 1.2184 0.8965 1.3955 1.1191

antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

solute carrier family 7 (cationic amino acid transporter, y+ system), member 1

guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2

solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6

29070 CCDC113 coiled-coil domain containing 113 0.00244311486 0.006211297444 3.1780 1.5316 4.0204 1.1966 1.4892 5.4583 1.0019100289511 LOC100289511 uncharacterized LOC100289511 0.00152454316 0.004067229164 3.1771 3.3801 2.2908 2.3334 3.5360 2.6418 1.534964064 OXCT2 3-oxoacid CoA transferase 2 0.00054559446 0.001597061275 3.1763 0.4777 1.3227 1.4011 0.4262 0.6505 1.006858477 SRPRB signal recognition particle receptor, B subunit 7.23525741E-10 8.89654262E-09 3.1758 0.0630 0.0867 0.2547 0.2285 0.0118 0.35762571 GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.00649193857 0.01479799171 3.1724 0.7527 1.1591 1.5974 0.5256 0.7836 1.06796752 SSTR2 somatostatin receptor 2 0.01085866019 0.023211211855 3.1703 0.9914 1.0411 1.6790 1.2301 0.5163 1.003351728 POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 7.06083183E-11 1.24894017E-09 3.1682 0.6200 14.5652 1.1110 0.8042 11.1494 1.08279371 KIF3B kinesin family member 3B 4.56788515E-09 4.36529275E-08 3.1668 1.2915 1.2832 1.1514 1.1092 1.1668 1.25971376 CPT2 carnitine palmitoyltransferase 2 4.53688721E-12 1.41705988E-10 3.1652 2.3129 1.0541 1.5254 2.2804 1.5307 1.795010661 KLF1 Kruppel-like factor 1 (erythroid) 0.00115788048 0.003174829245 3.1643 0.0983 0.3639 0.5748 0.1789 0.2756 0.5443672 BRCA1 breast cancer 1, early onset 6.4144174E-06 2.80863251E-05 3.1630 0.6661 3.7953 0.8860 0.1792 3.5507 0.691984720 PIGO phosphatidylinositol glycan anchor biosynthesis, class O 1.90733458E-11 4.38927172E-10 3.1614 0.9711 1.1092 1.6591 1.1313 1.6740 1.85307422 VEGFA vascular endothelial growth factor A 0.00210312471 0.00543079348 3.1609 0.8750 1.7897 0.8083 0.7225 1.7934 1.215855559 HAUS7 HAUS augmin-like complex, subunit 7 2.40393691E-09 2.48583674E-08 3.1597 0.7337 0.3752 0.6585 0.5528 0.3688 0.722228964 GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 4.54084259E-15 1.03712845E-12 3.1593 1.4832 2.6336 3.0914 1.0957 3.3334 3.183655851 PSENEN presenilin enhancer 2 homolog (C. elegans) 3.98983076E-10 5.36834961E-09 3.1593 0.4576 1.4790 2.0683 0.4481 0.5741 0.588055897 MESP1 mesoderm posterior 1 homolog (mouse) 0.00019881518 0.000639568821 3.1590 0.8187 1.1361 1.3723 0.5974 0.7091 1.8651148113 CILP2 cartilage intermediate layer protein 2 0.00019560877 0.000630363928 3.1587 0.8738 1.7776 0.9305 0.2955 0.8991 0.505223151 GRAMD4 GRAM domain containing 4 9.92162613E-11 1.64508124E-09 3.1580 0.8347 0.8156 0.8274 0.5111 0.6327 0.700484313 VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 1.72554559E-10 2.61870174E-09 3.1563 3.3845 1.3851 1.4929 3.1448 2.0036 1.6857587 BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.33326865E-09 1.50751763E-08 3.1541 0.8091 1.0355 1.1719 0.5162 1.2990 1.082210497 UNC13B unc-13 homolog B (C. elegans) 0.00033286638 0.001023756017 3.1540 1.1402 1.0464 0.7765 0.8619 1.1620 0.8284284649 SMG7-AS1 DKFZP564C196 protein 0.00245939045 0.006246591925 3.1539 3.2401 4.9808 1.7613 3.7560 5.4832 1.72949787 DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00041194689 0.00124086606 3.1539 1.9466 1.6279 1.6957 1.5340 1.7467 2.133254757 FAM20A family with sequence similarity 20, member A 0.01189983649 0.02513395127 3.1530 0.3435 1.3776 0.5066 0.3529 1.1385 0.3855622 BDH1 3-hydroxybutyrate dehydrogenase, type 1 8.59829526E-13 3.86014867E-11 3.1525 0.7804 0.8624 0.8485 0.8300 1.4112 1.734291695 RRP7B ribosomal RNA processing 7 homolog B (S. cerevisiae) 2.51139802E-08 1.93213746E-07 3.1525 3.9038 1.4842 2.2758 2.1774 2.1105 2.187927429 HTRA2 HtrA serine peptidase 2 3.86975526E-11 7.65239915E-10 3.1486 2.2367 3.1210 2.8629 1.2694 1.7639 1.9348266675 BEST4 bestrophin 4 0.00030759711 0.000953744181 3.1469 0.1845 0.7847 0.5942 0.2804 0.6167 0.377054976 C20orf27 chromosome 20 open reading frame 27 1.07039873E-10 1.76042534E-09 3.1467 1.2148 1.9085 1.6339 0.8085 1.7985 2.1573170463 SSBP4 single stranded DNA binding protein 4 1.23967585E-09 1.41659519E-08 3.1453 1.9686 1.6264 2.4050 1.0512 1.2238 1.9725677826 SNORA45 small nucleolar RNA, H/ACA box 45 0.00105166717 0.002906680158 3.1452 0.3686 0.6033 1.3014 0.5001 0.5509 0.511029927 SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.37063292E-11 5.20002458E-10 3.1445 1.0086 1.4755 1.2025 0.9296 2.3660 1.7603

3002 GZMB 0.00170732484 0.00449643118 3.1439 0.2255 0.4814 1.7407 0.5785 0.3379 1.191855572 FOXRED1 FAD-dependent oxidoreductase domain containing 1 3.20343059E-08 2.39105734E-07 3.1430 0.3927 0.5054 0.6701 0.4834 0.2923 0.614780179 MYO19 myosin XIX 1.75080149E-10 2.64823219E-09 3.1428 0.1864 0.1811 0.2071 0.2490 0.2171 0.29598662 EIF3B eukaryotic translation initiation factor 3, subunit B 1.08577366E-11 2.76975904E-10 3.1423 0.9178 0.9065 0.8207 1.1834 1.6226 1.533210376 TUBA1B tubulin, alpha 1b 1.82483667E-07 1.13683654E-06 3.1418 2.7474 4.3331 1.8403 1.9330 5.2144 2.56905351 PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 3.55244192E-07 2.06064186E-06 3.1358 2.0651 1.4653 2.0052 0.9751 1.2518 2.024323404 EXOSC2 exosome component 2 2.88956056E-10 4.12484769E-09 3.1355 2.1794 2.5395 2.0288 2.0615 4.0213 2.53652873 GPS1 G protein pathway suppressor 1 2.6112204E-13 1.64122904E-11 3.1340 2.1518 4.0064 0.9488 2.1810 9.5221 0.65322672 GFI1 growth factor independent 1 transcription repressor 8.8737832E-10 1.05698674E-08 3.1326 1.8055 1.8482 1.8898 1.4034 2.8707 3.12252068 ERCC2 excision repair cross-complementation group 2 8.90952479E-12 2.35593107E-10 3.1315 0.8686 0.2433 0.6104 0.8064 0.3379 0.751826145 IRF2BP1 interferon regulatory factor 2 binding protein 1 7.72513313E-12 2.14193676E-10 3.1306 2.0173 3.1579 2.0180 1.8074 4.7641 3.154410555 AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.8875227E-09 2.02399147E-08 3.1303 1.4904 1.3252 1.4909 0.8451 0.6585 1.831080149 ZC3H12A zinc finger CCCH-type containing 12A 2.93605568E-12 9.95317427E-11 3.1282 1.3133 1.4399 1.7856 0.8619 1.0343 2.1183

7531 YWHAE 1.30965245E-10 2.06470832E-09 3.1279 1.2181 2.6999 1.1978 1.4734 5.2079 2.36585531 PPP4C protein phosphatase 4, catalytic subunit 2.25176011E-15 6.53081916E-13 3.1267 1.7740 3.6945 2.2398 1.4538 4.1421 2.2705

146206 RLTPR 7.88112832E-11 1.35724766E-09 3.1243 1.4761 1.2862 1.5343 1.0868 1.2641 1.60758458 TTF2 transcription termination factor, RNA polymerase II 1.89786637E-09 2.0338894E-08 3.1237 1.9315 3.6616 2.2433 1.8494 5.6534 3.328255154 MSTO1 misato 1, mitochondrial distribution and morphology regulator 7.16144843E-12 2.01935163E-10 3.1234 1.7349 1.9713 1.6567 1.7718 2.9468 1.806157106 NAT14 N-acetyltransferase 14 (GCN5-related, putative) 2.55957538E-07 1.5349052E-06 3.1227 1.0001 1.6836 1.5624 0.6908 1.2474 1.397265260 SELRC1 Sel1 repeat containing 1 4.62525851E-07 2.60199272E-06 3.1218 1.5390 3.1805 1.4100 1.5300 2.8152 1.3997

4722 NDUFS3 8.85839358E-13 3.93821332E-11 3.1206 0.3321 0.3321 0.3321 0.3970 0.3970 0.39709410 SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 2.22335064E-13 1.48809754E-11 3.1186 2.1720 7.3939 2.4524 0.6560 3.5444 1.39661917 EEF1A2 eukaryotic translation elongation factor 1 beta 2 0.00099723548 0.002770486048 3.1176 0.4608 1.2407 0.6078 0.2483 0.5129 0.434053 ACP2 acid phosphatase 2, lysosomal 1.22648714E-08 1.02283766E-07 3.1164 0.3009 0.3356 0.1397 0.4248 0.3979 0.4846170850 KCNG3 potassium voltage-gated channel, subfamily G, member 3 0.01166719708 0.024728340692 3.1159 1.2295 2.6800 1.4112 0.6689 2.7302 2.235654517 PUS7 pseudouridylate synthase 7 (putative) 1.35033706E-07 8.66339844E-07 3.1136 0.6945 1.8497 1.1971 0.5027 1.9312 1.22125987 TRIM27 tripartite motif containing 27 3.45732334E-14 4.04950077E-12 3.1136 0.4546 0.5160 0.5042 0.5440 0.7302 0.72637264 TSTA3 tissue specific transplantation antigen P35B 2.97765999E-11 6.22572065E-10 3.1130 1.7077 1.7348 1.6934 1.3671 1.9312 2.619350 ACO2 aconitase 2, mitochondrial 7.4263937E-11 1.29480024E-09 3.1124 1.6867 1.7361 1.4871 1.3099 1.3792 0.7128139735 ZFP92 similar to Zinc finger protein 92 (Zfp-92) 0.00112025576 0.003082263705 3.1123 0.0190 0.1102 0.1600 0.0364 0.0499 0.14573313 HSPA9 heat shock 70kDa protein 9 (mortalin) 1.08078003E-10 1.77590042E-09 3.1090 1.4947 1.3432 1.7584 1.7750 2.3156 2.47898351 HIST1H3D histone cluster 1, H3d 3.1649388E-07 1.85888016E-06 3.1089 0.3321 0.3321 0.3321 0.3970 0.3970 0.39701317 SLC31A1 solute carrier family 31 (copper transporter), member 1 1.13233972E-05 4.69802711E-05 3.1063 7.3595 1.4015 3.1164 3.2510 1.1611 3.20562318 FLNC filamin C, gamma 0.01169688421 0.024788386496 3.1047 1.1622 1.6273 1.0862 0.6756 0.6454 0.6859643155 SMIM15 small integral membrane protein 15 4.5598886E-14 4.76715125E-12 3.1042 1.7525 1.6121 1.6782 1.6727 2.7990 2.2303113115 MTFR2 mitochondrial fission regulator 2 1.84374482E-05 7.32367508E-05 3.1040 3.3006 2.3170 2.2784 2.5370 2.1830 2.46115777 PTPN6 protein tyrosine phosphatase, non-receptor type 6 4.45013709E-09 4.26615451E-08 3.1031 2.1215 2.4899 2.7487 1.4953 3.0784 2.595423028 KDM1A lysine (K)-specific demethylase 1A 1.04666941E-16 1.36605311E-13 3.1025 2.1777 2.1182 1.6068 2.4850 2.6743 2.543723065 EMC1 ER membrane protein complex subunit 1 1.56357884E-10 2.40891337E-09 3.0985 0.1703 0.2842 0.5528 0.2762 1.8225 0.26113615 IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 1.39813245E-09 1.56414625E-08 3.0977 1.4810 1.3492 1.8566 1.0935 1.5837 1.58875724 PTAFR platelet-activating factor receptor 0.01911549409 0.037948534126 3.0969 0.0853 0.2493 0.1898 0.2903 0.2340 0.143323534 TNPO3 transportin 3 1.58457105E-15 5.36233287E-13 3.0953 8.0517 2.5706 1.2392 8.3177 4.2349 3.75218449 DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 9.05537032E-14 7.40214508E-12 3.0947 0.4158 0.4321 0.3885 0.4682 0.5117 0.48066713 SQLE squalene epoxidase 4.08550018E-08 2.98781501E-07 3.0946 2.5797 1.6518 2.0320 1.8756 2.0681 2.5031128272 ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 7.87474835E-07 4.19741546E-06 3.0943 0.5105 0.6387 0.7469 0.4240 0.6491 0.7852650368 LOC650368 similar to beta-1,4-mannosyltransferase 0.00102939636 0.002851164221 3.0922 0.4791 0.1482 0.2757 0.6209 0.3230 0.237711151 CORO1A coronin, actin binding protein, 1A 1.95345356E-10 2.91613591E-09 3.0896 1.5215 2.0361 2.3596 1.2538 2.3874 2.63175442 POLRMT polymerase (RNA) mitochondrial (DNA directed) 6.28429379E-13 3.06313506E-11 3.0892 2.4589 1.9716 1.8466 1.8460 2.8561 2.485811316 COPE coatomer protein complex, subunit epsilon 2.44976274E-12 8.59620829E-11 3.0880 0.9230 2.8193 3.6783 0.8703 7.1566 2.2472327 APEH acylaminoacyl-peptide hydrolase 4.10044025E-11 7.98755269E-10 3.0866 1.1898 2.5153 1.8697 1.1804 2.7445 2.722357465 TBC1D24 TBC1 domain family, member 24 1.94418313E-12 7.27953159E-11 3.0834 0.4567 0.8854 0.6920 0.3187 1.5631 0.6972356 FASLG Fas ligand (TNF superfamily, member 6) 0.00187478166 0.004888826957 3.0823 1.0496 1.4477 1.3831 0.6211 1.1812 0.69689670 IPO13 importin 13 1.39890998E-13 1.02226696E-11 3.0821 1.1377 1.0434 1.3346 0.8127 1.5002 1.455410459 MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 4.80422482E-11 9.10609915E-10 3.0802 3.4517 0.9836 1.4767 1.0965 1.1726 1.426684962 AJUBA jub, ajuba homolog (Xenopus laevis) 0.00012193356 0.000411520134 3.0779 1.0525 1.2820 1.5005 1.0681 1.1383 1.3344728340 GTF2H2C general transcription factor IIH, polypeptide 2C 8.65294324E-10 1.03337633E-08 3.0768 2.5341 1.6499 2.2981 2.0341 2.2269 2.472229889 GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 4.87731876E-09 4.62203537E-08 3.0767 1.9413 1.5600 1.6296 1.7936 2.2643 2.313755152 DALRD3 DALR anticodon binding domain containing 3 9.63212296E-13 4.18047864E-11 3.0735 1.5514 2.5658 1.9478 1.4899 2.9266 2.759557165 GJC2 gap junction protein, gamma 2, 47kDa 0.00282438687 0.007065607454 3.0729 0.0779 0.0757 0.1811 0.0043 0.0346 0.09754172 MCM3 minichromosome maintenance complex component 3 1.2627039E-08 1.05016503E-07 3.0727 2.2225 1.9226 1.6899 2.1228 1.8762 2.5997283807 FBXL22 F-box and leucine-rich repeat protein 22 0.00063727949 0.001838101154 3.0726 0.2130 0.5733 0.5850 0.3935 0.4034 0.441879039 DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 6.13655867E-15 1.28881839E-12 3.0726 2.1574 3.0302 2.5479 1.3037 3.6308 3.53283566 IL4R interleukin 4 receptor 1.45718341E-10 2.26199233E-09 3.0715 2.2707 1.6659 2.1415 2.3738 2.0875 2.79349911 TMCC2 transmembrane and coiled-coil domain family 2 2.22940762E-07 1.3574054E-06 3.0715 0.5272 0.6480 0.8829 0.4911 0.4228 0.74326491 STIL SCL/TAL1 interrupting locus 1.45956822E-07 9.29889487E-07 3.0710 1.1226 0.9540 0.8547 1.0522 1.2690 1.1236115939 TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 4.38153225E-13 2.4187117E-11 3.0694 1.0020 0.2393 1.0130 0.3941 0.1107 0.9745

117166 WFIKKN1 0.00044182539 0.00131955436 3.0676 0.2398 0.1742 0.1408 0.0906 0.1089 0.110755738 ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 4.52187721E-14 4.76715125E-12 3.0623 1.3492 2.2455 1.4405 0.9287 2.0466 1.3026121642 ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 2.46551335E-11 5.37618655E-10 3.0622 1.9677 2.0973 1.4564 1.6047 2.2827 1.080551069 MRPL2 mitochondrial ribosomal protein L2 1.19455538E-11 2.98181911E-10 3.0616 0.3321 0.3321 0.3321 0.3970 0.3970 0.39709732 DOCK4 dedicator of cytokinesis 4 0.01044169034 0.02244594892 3.0615 0.7537 1.4216 1.7978 0.4990 0.5381 1.634257650 KIAA1524 KIAA1524 1.67986282E-05 6.7341934E-05 3.0594 0.1738 0.4384 0.3244 0.2308 0.3334 0.25507691 ZNF132 zinc finger protein 132 0.00014718874 0.000487127807 3.0593 1.4160 1.9427 2.2846 1.8063 2.0106 2.56002794 GNL1 guanine nucleotide binding protein-like 1 2.23641617E-13 1.49137942E-11 3.0580 0.4616 0.7195 0.4779 0.4785 0.7318 0.494155739 CARKD hypothetical protein FLJ10769 1.71383806E-09 1.86400292E-08 3.0577 0.6195 0.7799 0.7949 0.7611 0.7342 0.8310

10797 MTHFD2 8.35921733E-09 7.27678033E-08 3.0577 1.5956 1.8637 1.8255 1.3387 3.8252 2.631365989 DLK2 delta-like 2 homolog (Drosophila) 1.76564859E-05 7.03947875E-05 3.0566 1.2617 2.4256 1.4317 1.2148 1.5533 1.207679070 KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1 0.00022901315 0.000727617495 3.0551 0.3318 0.3225 0.3054 1.0229 0.4134 0.328211091 WDR5 WD repeat domain 5 2.12430979E-10 3.14804449E-09 3.0545 1.2268 0.9888 1.1927 1.0519 1.5296 1.928629926 GMPPA GDP-mannose pyrophosphorylase A 1.61654418E-10 2.48214246E-09 3.0541 2.0090 2.4552 2.4810 1.7897 2.7052 2.26416478 SIAH2 siah E3 ubiquitin protein ligase 2 1.10701267E-09 1.28021111E-08 3.0527 2.3381 2.0000 1.4999 2.1425 2.8524 2.934810645 CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.50389298E-12 5.99981059E-11 3.0502 0.7862 0.8873 0.7032 0.7076 0.9659 0.79648187 ZNF239 zinc finger protein 239 0.00018954479 0.000612225994 3.0496 0.6533 0.6297 0.5728 0.9029 0.4520 0.667510189 ALYREF Aly/REF export factor 6.90523373E-09 6.19596129E-08 3.0475 0.9369 1.4026 1.7834 0.8726 1.3128 2.12244580 MTX1 metaxin 1 9.13465942E-13 4.03084856E-11 3.0473 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

4793 NFKBIB 8.15253322E-14 6.96089192E-12 3.0451 3.7693 3.7225 2.9447 2.3554 1.1809 1.62409173 IL1RL1 interleukin 1 receptor-like 1 0.0104896109 0.022522464192 3.0441 0.2122 0.3417 0.4281 0.2800 0.2601 0.335727166 PRELID1 PRELI domain containing 1 4.80037836E-09 4.55886245E-08 3.0403 1.3088 1.2873 0.4843 0.0928 5.1281 0.5169

25974 MMACHC 2.59930145E-07 1.55719462E-06 3.0374 1.2488 1.0634 0.8990 2.2218 0.6715 0.43715819 PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.00074908156 0.002133959827 3.0369 2.1993 2.7170 2.5356 1.5522 1.8510 2.134457405 SPC25 SPC25, NDC80 kinetochore complex component 8.54887849E-05 0.000298557163 3.0356 1.2769 1.1329 1.9707 1.1323 0.7380 1.82745032 P2RY11 purinergic receptor P2Y, G-protein coupled, 11 0.00055132965 0.001612855479 3.0356 0.2399 0.7787 1.4620 0.1188 0.4797 0.777984446 BRSK1 BR serine/threonine kinase 1 1.84195757E-05 7.31816671E-05 3.0354 0.5616 0.6860 0.7434 0.4994 0.6248 0.57463182 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 9.64788874E-09 8.26902362E-08 3.0348 1.3420 1.1188 1.2034 1.4107 1.7670 2.201381554 WBSCR16 Williams-Beuren syndrome chromosome region 16 3.27811565E-13 1.96636633E-11 3.0347 0.6449 1.0534 1.2535 0.7670 1.0499 1.607355192 DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 6.58598493E-09 5.96920222E-08 3.0304 1.0777 4.9234 3.1465 0.6905 2.5408 3.10309862 MED24 mediator complex subunit 24 3.86419064E-12 1.25188815E-10 3.0303 0.4174 0.5941 0.6026 0.6052 0.5858 0.70639654 TTLL4 tubulin tyrosine ligase-like family, member 4 8.06645527E-10 9.75448515E-09 3.0299 0.6580 1.0994 0.8161 0.5273 1.0971 0.7534199953 TMEM201 transmembrane protein 201 9.60167624E-07 5.01548966E-06 3.0294 0.6261 0.7670 1.1723 0.4821 0.7466 1.171710298 PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 3.9883771E-09 3.8784261E-08 3.0289 1.8078 1.4651 1.7929 1.7355 2.0073 2.072654884 RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 2.54352363E-10 3.68348124E-09 3.0281 5.5452 0.9123 4.2217 0.7840 0.3889 3.174223432 GPR161 G protein-coupled receptor 161 0.00692851769 0.015648686688 3.0272 0.5707 1.1363 0.7868 0.3429 0.7761 0.542879798 ARMC5 armadillo repeat containing 5 1.01148363E-08 8.61222225E-08 3.0257 1.7341 3.3704 2.1025 1.5795 4.0463 2.6601

granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing

NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta

methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria

23623 RUSC1 RUN and SH3 domain containing 1 1.63447184E-12 6.28738303E-11 3.0251 1.7209 1.6288 1.5394 1.0825 1.2530 1.223351726 DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 6.17381439E-07 3.3754619E-06 3.0248 0.4716 3.1645 1.1142 0.6525 2.2859 0.6412285601 GPR150 G protein-coupled receptor 150 4.92827153E-05 0.000179918836 3.0236 1.6367 5.0054 2.5134 1.1564 3.5513 2.5774

10273 STUB1 1.70585156E-07 1.07057432E-06 3.0227 1.4698 1.7909 1.6164 1.3029 3.4576 2.2604401551 WDR38 WD repeat domain 38 0.0058022367 0.013394626535 3.0193 0.7655 1.3229 1.0167 0.4543 0.7172 0.91715998 RGS3 regulator of G-protein signaling 3 3.40621333E-08 2.52590625E-07 3.0159 0.3887 0.4993 0.5534 0.3503 0.3941 0.33636398 SECTM1 secreted and transmembrane 1 0.00010869618 0.000370747913 3.0150 1.5637 1.5488 1.6305 1.0511 1.5587 1.404010322 SMYD5 SMYD family member 5 1.21852533E-08 1.01759117E-07 3.0131 1.6234 2.7991 1.2621 1.4081 4.2751 1.418914 AAMP angio-associated, migratory cell protein 8.68545586E-12 2.31701372E-10 3.0119 2.8697 2.7974 2.3807 2.0679 2.8095 1.402964855 FAM129B family with sequence similarity 129, member B 0.00020831214 0.00066776831 3.0105 1.1361 2.0248 1.4433 0.7147 0.7775 1.0915118424 UBE2J2 ubiquitin-conjugating enzyme E2, J2 1.06573606E-12 4.53919096E-11 3.0105 0.5361 0.9217 1.1462 0.5400 1.1760 1.360292999 ZBTB47 zinc finger and BTB domain containing 47 0.00070692879 0.002021756576 3.0093 0.7991 0.8916 1.9850 0.4075 0.8676 1.27332331 FMOD fibromodulin 0.01126551785 0.023963159748 3.0087 0.9187 0.8301 1.1302 0.6941 0.3113 0.818757665 RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 5.65919272E-06 2.50799829E-05 3.0076 1.7275 3.1300 1.5027 1.6182 3.8309 1.6445526 ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 2.83942493E-07 1.68502671E-06 3.0073 1.9346 2.6593 2.1377 1.5225 2.7070 2.5624255031 LINC00957 hypothetical protein FLJ35390 3.97793404E-08 2.91672596E-07 3.0054 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970407835 LOC407835 mitogen-activated protein kinase kinase 2 pseudogene 1.77281894E-06 8.77144537E-06 3.0052 0.1501 0.1064 0.1080 0.5014 0.0303 0.089426173 INTS1 integrator complex subunit 1 4.54969504E-12 1.41863529E-10 3.0030 0.9608 0.5974 0.7323 0.6794 0.6798 0.8606723790 HIST2H2AA4 histone cluster 2, H2aa4 7.14682569E-08 4.92037676E-07 3.0019 1.3732 1.1820 1.2059 1.7508 1.7023 2.35648341 HIST1H2BN histone cluster 1, H2bn 1.74897456E-07 1.09330356E-06 3.0010 3.5021 2.5486 1.4635 2.1303 2.7017 3.90861351 COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.84707515E-11 6.04904153E-10 3.0009 1.6832 1.6212 1.5327 1.6384 2.7265 2.39545754 PTK7 protein tyrosine kinase 7 8.721224E-05 0.000303763257 2.9986 0.4474 0.9160 0.8875 0.4801 0.6674 0.77396625 SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 6.93403129E-12 1.97042954E-10 2.9978 0.6905 1.1922 0.8830 0.8214 1.7880 1.262151148 CERCAM cerebral endothelial cell adhesion molecule 0.00378695543 0.009185616574 2.9977 0.3712 0.8194 0.7103 0.2349 0.6579 0.653611135 CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 0.01789342059 0.035845694665 2.9974 1.4430 2.4223 1.6842 0.8789 1.2252 1.316710267 RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00156878554 0.004173682218 2.9971 0.5991 1.4763 0.7600 0.3038 0.5705 0.800955872 PBK PDZ binding kinase 0.00044823766 0.001335866657 2.9953 1.7545 1.4195 1.7732 1.2982 1.5606 1.9992388906 LOC388906 opioid growth factor receptor pseudogene 1.42864038E-05 5.80478476E-05 2.9950 3.2689 3.4755 1.6362 2.4213 3.3152 1.9382100125556 FAM86JP family with sequence similarity 86, member A pseudogene 0.00100674197 0.002794772008 2.9929 0.9005 1.6446 1.8001 0.8493 1.9620 1.996426027 ACOT11 acyl-CoA thioesterase 11 0.01954881582 0.038678501641 2.9926 0.5797 1.1529 1.0790 0.3432 0.6810 0.8155332 BIRC5 baculoviral IAP repeat containing 5 0.00011372932 0.000386041637 2.9908 0.5678 0.4941 1.8621 0.4696 0.4561 1.8076431705 ASTL astacin-like metallo-endopeptidase (M12 family) 0.00662189387 0.015039806686 2.9896 0.3802 0.6553 0.4427 0.2037 0.2353 0.16153265 HRAS Harvey rat sarcoma viral oncogene homolog 5.43403134E-12 1.63845909E-10 2.9871 1.4474 2.7610 2.8878 1.1168 4.5018 2.720529090 TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) 8.01468473E-06 3.43846723E-05 2.9864 2.7410 4.8876 1.4441 2.2504 9.7969 1.6420388569 ZNF324B zinc finger protein 324B 1.27526323E-07 8.22506519E-07 2.9864 1.1409 1.7706 2.1242 0.6823 1.8703 2.024931 ACACA acetyl-CoA carboxylase alpha 2.84764468E-09 2.88746746E-08 2.9855 0.3691 0.5381 0.6039 0.3212 0.6392 0.668480347 COASY Coenzyme A synthase 3.60343156E-14 4.16720895E-12 2.9842 1.4038 1.4539 2.1051 1.2776 2.4604 2.3506100506668 DYNLL1-AS1 DYNLL1 antisense RNA 1 0.00051454253 0.001515917617 2.9842 0.1456 11.6927 0.5858 0.1446 3.5472 0.6406201292 TRIM65 tripartite motif-containing 65 2.10524636E-11 4.74901994E-10 2.9836 1.0125 1.4300 1.4229 0.8774 2.7587 1.812090113 VWA5B2 von Willebrand factor A domain containing 5B2 0.00833661948 0.018419191188 2.9833 0.7194 1.2369 0.8778 0.5419 0.7125 0.634180020 FOXRED2 FAD-dependent oxidoreductase domain containing 2 2.19323215E-06 1.05989785E-05 2.9825 0.8790 1.2705 1.3939 0.8245 1.6771 1.1352387097 C6orf147 chromosome 6 open reading frame 147 0.00578595387 0.013362101763 2.9823 0.0088 11.0029 0.1221 0.0097 1.5253 0.195591978 TPGS1 tubulin polyglutamylase complex subunit 1 5.31719081E-07 2.94228379E-06 2.9811 1.6950 2.2824 2.0739 1.6315 2.6566 3.05989253 NUMBL numb homolog (Drosophila)-like 8.19308156E-07 4.34933139E-06 2.9731 0.8044 2.0109 1.4501 0.5776 2.0717 1.371055616 ASAP3 development and differentiation enhancing factor-like 1 0.00048360661 0.00143193323 2.9728 0.8792 1.1486 1.0880 0.6219 1.3526 1.09745832 ALDH18A1 aldehyde dehydrogenase 18 family, member A1 8.42499991E-12 2.27114953E-10 2.9726 1.6677 1.7977 1.5874 1.2408 2.2058 1.79875447 POR P450 (cytochrome) oxidoreductase 5.43192166E-10 6.96505772E-09 2.9718 0.9315 0.1352 0.2692 0.7647 0.1942 0.53369942 XYLB xylulokinase homolog (H. influenzae) 0.0003498037 0.001069368104 2.9693 0.4478 0.7799 0.7025 0.4236 0.8038 0.706179682 MLF1IP MLF1 interacting protein 4.17565088E-05 0.000154654204 2.9674 1.0343 1.1989 0.8710 0.8280 1.3327 1.074379023 NUP37 nucleoporin 37kDa 3.71455864E-10 5.07647087E-09 2.9663 0.4344 1.0604 0.6567 0.2896 1.3319 0.61296608 SMO smoothened, frizzled class receptor 0.01056674463 0.022664110571 2.9656 0.6461 0.6871 0.4984 0.7336 0.4813 0.4585347240 KIF24 kinesin family member 24 0.00011075345 0.000376920668 2.9641 0.4987 1.1361 1.6811 1.4326 0.5728 1.24347542 ZFPL1 zinc finger protein-like 1 5.00339466E-09 4.71715241E-08 2.9634 0.2172 9.4951 1.3558 0.1553 3.0665 0.631010652 YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 1.8478507E-13 1.27893667E-11 2.9631 1.5251 0.9583 1.2032 1.7296 1.4089 1.3901256933 NPB neuropeptide B 0.01586824327 0.032266252055 2.9619 0.6379 0.2255 0.5129 0.2865 0.1113 0.25737706 TRIM25 tripartite motif containing 25 5.44577743E-11 1.01020553E-09 2.9618 1.5897 3.6739 1.3625 1.6087 4.2041 2.37583483 IGFALS insulin-like growth factor binding protein, acid labile subunit 0.00620886476 0.014216588578 2.9612 0.1470 0.1038 0.0642 0.0220 0.0592 0.149029903 CCDC106 coiled-coil domain containing 106 5.79413503E-06 2.56282826E-05 2.9612 1.1442 3.4712 1.5577 1.0254 3.4997 1.443730968 STOML2 stomatin (EPB72)-like 2 2.17296827E-10 3.19939373E-09 2.9609 1.7923 1.8077 2.0957 1.0755 1.7925 2.207064223 MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 3.22925312E-12 1.07870042E-10 2.9608 1.2729 1.9025 1.3904 1.3518 2.3465 2.129284916 CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 1.19680964E-09 1.36932409E-08 2.9606 0.2837 1.0812 0.9195 0.3929 0.8095 0.88075982 RFC2 replication factor C (activator 1) 2, 40kDa 2.29026738E-08 1.78531423E-07 2.9601 2.1248 2.2118 2.0461 2.1868 3.3366 2.70358266 UBL4A ubiquitin-like 4A 2.26886602E-14 3.02856103E-12 2.9563 1.7843 2.2491 1.4803 1.3652 2.6869 1.3403898 CCNE1 cyclin E1 9.21074219E-06 3.90212412E-05 2.9551 0.6601 0.7407 1.6616 0.5438 0.4744 1.6384160419 C12orf50 chromosome 12 open reading frame 50 0.00012416293 0.000418348723 2.9545 0.0577 0.0157 0.0598 0.0360 0.2118 0.11698362 HIST1H4K histone cluster 1, H4k 2.9023407E-08 2.19311928E-07 2.9529 2.4246 2.2553 1.3028 2.0550 1.4591 1.258923450 SF3B3 splicing factor 3b, subunit 3, 130kDa 1.62080317E-12 6.27443125E-11 2.9526 2.1922 1.2906 1.6678 2.2284 2.2265 4.2408

6520 SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 9.1705216E-09 7.90768148E-08 2.9525 5.9706 1.9738 2.5908 5.2229 2.3004 2.603329074 MRPL18 mitochondrial ribosomal protein L18 5.3305461E-10 6.86397029E-09 2.9520 3.3749 4.8303 2.0287 2.6233 6.4579 2.785223753 SDF2L1 stromal cell-derived factor 2-like 1 1.11698743E-08 9.42706439E-08 2.9511 1.5568 2.2261 2.4703 0.8630 2.3338 2.518455684 RABL6 RAB, member RAS oncogene family-like 6 7.03051477E-15 1.43874317E-12 2.9510 0.3427 0.9576 0.5382 0.4256 1.1563 0.716210574 CCT7 chaperonin containing TCP1, subunit 7 (eta) 3.41680415E-11 6.925329E-10 2.9481 3.0037 2.2131 1.7252 2.2057 3.7939 3.50231687 DFNA5 deafness, autosomal dominant 5 0.00776157008 0.017305602016 2.9474 0.9925 1.3829 1.7781 0.8682 1.3422 1.82106567 SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.00080196558 0.00227256747 2.9451 1.4704 1.5683 1.1997 1.2163 0.8660 1.2063941 CD80 CD80 molecule 0.00108230638 0.002985492473 2.9449 0.1579 0.3162 1.0260 0.2438 0.3152 0.61372177 FANCD2 Fanconi anemia, complementation group D2 1.45628034E-06 7.32429244E-06 2.9443 0.6243 1.3589 1.4466 0.3598 0.7671 0.939357176 VARS2 valyl-tRNA synthetase 2, mitochondrial 9.6700275E-11 1.6092053E-09 2.9442 0.3546 0.3907 0.4040 0.4081 0.4294 0.425654836 BSPRY B-box and SPRY domain containing 2.36959771E-05 9.17798771E-05 2.9410 0.5822 1.1332 1.7448 0.4717 0.9425 1.866226240 FAM50B family with sequence similarity 50, member B 6.28967164E-09 5.72050175E-08 2.9406 1.3461 2.8430 1.8491 1.6850 2.6612 1.6434

6603 SMARCD2 9.41813566E-16 4.17311256E-13 2.9372 1.3205 2.1250 1.5055 1.1753 2.3777 1.601880222 TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 1.80613474E-10 2.72291205E-09 2.9372 3.1361 2.4289 1.9169 3.1011 3.3476 2.86204723 NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 5.07775948E-14 5.12601222E-12 2.9356 0.8954 0.8981 0.8604 1.0548 1.0669 0.86311293 COL6A3 collagen, type VI, alpha 3 0.00269002983 0.006771441925 2.9342 0.0408 0.0320 0.1970 0.1656 0.0771 0.195679754 ASB13 ankyrin repeat and SOCS box-containing 13 7.71404768E-08 5.26526258E-07 2.9337 1.7570 3.3196 1.8634 1.0094 2.6946 1.885258480 RHOU ras homolog family member U 0.00347148225 0.008499386798 2.9283 0.7776 0.8420 0.6294 0.7017 0.9278 0.7392729747 ZNF878 zinc finger protein 878 0.02562909896 0.048862155286 2.9280 1.3605 2.3866 2.2174 1.1211 1.9709 1.762479576 NKAP NFKB activating protein 5.83345507E-07 3.20568094E-06 2.9280 2.0004 0.8374 0.7941 2.2332 1.4477 1.001980262 C16orf70 chromosome 16 open reading frame 70 5.02667504E-07 2.8002258E-06 2.9268 1.2411 0.4484 0.9655 1.0427 0.6096 1.178423354 HAUS5 HAUS augmin-like complex, subunit 5 7.25382222E-09 6.44032262E-08 2.9266 1.5957 1.9116 2.0155 1.3054 1.9513 1.9335161725 OTUD7A OTU domain containing 7A 0.00063281782 0.001827540259 2.9236 0.7976 1.1592 0.5600 0.5845 0.9703 0.48281209 CLPTM1 cleft lip and palate associated transmembrane protein 1 4.21743328E-11 8.19797243E-10 2.9230 1.2405 0.9844 1.1563 1.6795 1.3454 1.61779238 TBRG4 transforming growth factor beta regulator 4 1.8111171E-11 4.20492142E-10 2.9223 1.9515 2.7418 1.7659 1.8328 4.4981 1.677255201 MAP1S microtubule-associated protein 1S 1.33861729E-13 9.94277035E-12 2.9210 1.2735 2.6530 2.4631 1.0570 2.8466 1.87186663 SOX10 SRY (sex determining region Y)-box 10 0.01553904568 0.031716872506 2.9206 0.0231 0.1922 0.0868 0.0761 0.0100 0.13451595 CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 4.13975077E-06 1.88350413E-05 2.9197 1.1275 1.7122 1.1901 1.0777 2.1067 1.704257662 CAMSAP3 KIAA1543 0.00221201273 0.005675076744 2.9183 0.2589 0.6217 0.5241 0.3053 0.5891 0.44308363 HIST1H4J histone cluster 1, H4j 3.72580941E-08 2.74286824E-07 2.9175 2.2427 2.3664 1.7632 1.7066 2.0383 2.296657805 CCAR2 KIAA1967 5.19564309E-16 3.08000989E-13 2.9132 1.4727 1.3267 1.1932 1.5030 1.7134 1.058151564 HDAC7 histone deacetylase 7 3.30563938E-11 6.74867517E-10 2.9118 0.6194 1.2741 0.8857 0.4959 1.4233 0.95751965 EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 8.15437028E-10 9.85101799E-09 2.9116 1.6798 6.1534 0.6677 1.0338 8.1888 1.196810295 BCKDK branched chain ketoacid dehydrogenase kinase 2.27473453E-08 1.77699655E-07 2.9115 1.0926 2.4586 1.7091 0.6418 1.4039 1.5014122616 C14orf79 chromosome 14 open reading frame 79 0.00022982395 0.000730066621 2.9115 0.6752 1.5754 1.0345 0.7203 0.8165 1.50161543 CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.01046675212 0.022483027541 2.9074 0.8655 1.1452 1.4568 0.5899 0.9973 1.486823560 GTPBP4 GTP binding protein 4 1.47070539E-09 1.63161681E-08 2.9069 1.8624 1.8374 1.8037 1.8229 4.1009 2.34568487 GEMIN2 gem (nuclear organelle) associated protein 2 2.13296252E-06 1.03405389E-05 2.9068 1.5572 1.9960 1.5025 1.1256 1.5273 1.880555127 HEATR1 HEAT repeat containing 1 6.79793877E-10 8.44979165E-09 2.9062 1.3438 0.9467 1.0516 1.8562 1.2990 1.470479071 ELOVL6 ELOVL fatty acid elongase 6 5.31496241E-07 2.94198707E-06 2.9055 2.1931 2.0315 1.7687 1.9739 2.1167 2.07078882 ZNF259 ZPR1 zinc finger 2.22216692E-11 4.95768425E-10 2.9042 1.7565 2.0664 2.0081 1.3813 2.5627 2.36869761 MLEC malectin 1.59463378E-10 2.45468815E-09 2.9041 1.6455 4.7741 1.9075 2.1005 9.0443 3.061429995 LMCD1 LIM and cysteine-rich domains 1 2.07518747E-05 8.15086533E-05 2.9036 0.1497 0.0871 0.4069 0.0202 0.2600 0.356854587 MXRA8 matrix-remodelling associated 8 0.00012204319 0.000411738035 2.9033 0.2640 0.1515 0.4495 0.2384 0.1722 0.2085176 ACAN aggrecan 0.00692727133 0.015647805879 2.9001 0.1314 0.5182 0.4205 0.0944 0.4919 0.33716749 SSRP1 structure specific recognition protein 1 9.41706579E-10 1.11371279E-08 2.8993 2.4346 1.7782 2.2754 1.6315 1.3861 1.8299

57664 PLEKHA4 0.00122111533 0.003331176356 2.8991 0.1087 0.1947 0.5055 0.1500 0.0371 0.406828973 MRPS18B mitochondrial ribosomal protein S18B 1.26518411E-12 5.14865122E-11 2.8977 0.6167 0.6466 0.6662 0.5739 0.8698 0.701984695 LOXL3 lysyl oxidase-like 3 0.00218564231 0.005616562744 2.8973 0.2364 0.2794 0.6716 0.3677 0.1940 0.368111129 CLASRP CLK4-associating serine/arginine rich protein 5.19341409E-10 6.71578643E-09 2.8963 1.9769 3.1874 1.7525 1.4161 3.5879 1.6090

26012 NSMF 3.03974891E-07 1.79168684E-06 2.8955 0.7006 1.2230 0.9867 0.5287 1.1024 0.84595226 PGD phosphogluconate dehydrogenase 9.15691056E-07 4.80514273E-06 2.8949 2.6061 2.3216 1.9628 1.9827 3.0174 2.774283475 DOHH deoxyhypusine hydroxylase/monooxygenase 4.77081906E-13 2.58671828E-11 2.8949 2.2964 2.0521 1.3725 1.7195 3.5880 1.452880755 AARSD1 alanyl-tRNA synthetase domain containing 1 6.00169235E-11 1.09444035E-09 2.8938 3.0817 2.6082 2.2017 3.2283 3.6657 2.713385026 C9orf37 chromosome 9 open reading frame 37 0.00022434924 0.000713916648 2.8938 1.3017 2.4880 5.5066 0.7355 1.9051 2.72115052 PRDX1 peroxiredoxin 1 1.88208153E-10 2.81880276E-09 2.8890 1.5412 2.3213 2.0198 1.4432 2.9517 1.7831340061 TMEM173 transmembrane protein 173 3.20621822E-08 2.39216085E-07 2.8884 1.6149 2.6728 2.0284 1.5797 2.7398 2.360484342 COG8 component of oligomeric golgi complex 8 5.38813462E-10 6.91862234E-09 2.8882 0.4126 19.3896 6.3840 1.2585 19.5587 4.5251374654 KIF7 kinesin family member 7 0.00311837302 0.007727001864 2.8876 0.6250 1.1475 0.7355 0.3161 0.5095 0.61095701 PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 4.43439448E-13 2.43319087E-11 2.8871 2.1995 1.3459 1.8580 2.6146 1.6861 2.2002347733 TUBB2B tubulin, beta 2B class IIb 1.16783409E-06 5.99906228E-06 2.8860 0.7210 2.0869 1.6202 0.3721 1.0740 1.284979734 KCTD17 potassium channel tetramerization domain containing 17 2.46312685E-11 5.37618655E-10 2.8859 0.9482 2.3790 1.1199 0.8720 1.3780 1.124210952 SEC61B Sec61 beta subunit 1.58442689E-09 1.74296497E-08 2.8834 4.0435 2.5497 3.3193 1.3393 1.9538 1.89232968 GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 1.8086302E-10 2.7244263E-09 2.8833 0.6166 0.5385 0.6065 0.6767 0.8154 0.6991440362 HERC2P4 hect domain and RLD 2 pseudogene 4 0.00062978518 0.001819932765 2.8830 0.0468 0.0046 0.0861 0.2154 0.0297 0.1720226 ALDOA aldolase A, fructose-bisphosphate 1.70739328E-09 1.8592068E-08 2.8823 1.2228 2.4870 1.9692 1.2484 3.4736 2.288028957 MRPS28 mitochondrial ribosomal protein S28 2.73798447E-08 2.08625739E-07 2.8810 2.2778 2.2173 1.2298 2.1906 2.8479 2.130927161 AGO2 argonaute RISC catalytic component 2 4.7331892E-09 4.50911539E-08 2.8809 1.4389 1.5750 2.2378 1.5228 1.4955 2.276851318 MRPL35 mitochondrial ribosomal protein L35 5.14442862E-13 2.72460869E-11 2.8809 2.5888 2.1424 1.5087 2.6083 2.5652 1.905226051 PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.76079107E-09 2.81188263E-08 2.8797 1.5853 3.7319 2.6538 1.6072 3.2356 2.641779833 GEMIN6 gem (nuclear organelle) associated protein 6 2.62819303E-08 2.01267154E-07 2.8794 1.1806 1.5322 1.1400 1.0723 1.9126 1.03053384 ICAM2 intercellular adhesion molecule 2 1.00296381E-08 8.55163545E-08 2.8772 1.6913 1.6674 1.0740 1.7263 1.6141 1.0416

STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

NMDA receptor synaptonuclear signaling and neuronal migration factor

10046 MAMLD1 mastermind-like domain containing 1 0.00099851254 0.002773612225 2.8767 0.5389 0.7819 0.8635 0.4368 0.9414 0.71755985 RFC5 replication factor C (activator 1) 5, 36.5kDa 1.95536429E-08 1.55408509E-07 2.8749 1.9124 2.3614 1.6938 1.0749 2.6114 1.576223254 KAZN kazrin, periplakin interacting protein 0.01201021969 0.025337805591 2.8744 0.1621 0.2627 0.3180 0.2119 0.1444 0.234280028 FBXL18 F-box and leucine-rich repeat protein 18 7.18357953E-11 1.26453146E-09 2.8741 1.6269 2.2446 1.7794 1.2605 3.4707 2.6298

871 SERPINH1 2.80103948E-08 2.12734775E-07 2.8740 0.5836 1.2278 0.8890 0.5655 1.1148 1.16966790 AURKA aurora kinase A 7.20809889E-07 3.88514404E-06 2.8739 0.7297 19.3983 3.0225 0.2483 5.4269 2.630256938 ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 2.55733382E-05 9.84360725E-05 2.8737 1.0141 3.6401 2.3684 1.1288 2.4572 2.289579643 CHMP6 chromatin modifying protein 6 4.07401283E-08 2.98238631E-07 2.8737 1.8407 1.5623 2.4762 1.0072 1.6408 2.5451219902 TMEM136 transmembrane protein 136 0.01739496265 0.034969826993 2.8733 1.0675 1.2730 1.1002 0.6405 0.9663 0.86653835 KIF22 kinesin family member 22 8.00321901E-12 2.19901982E-10 2.8730 1.7668 1.4039 2.2528 1.3544 1.7629 2.11342521 FUS fused in sarcoma 6.67489604E-08 4.62860344E-07 2.8726 1.4871 1.8716 1.2990 1.8720 3.2070 2.09055326 PLAGL2 pleiomorphic adenoma gene-like 2 8.38840139E-07 4.44398E-06 2.8695 2.4044 13.9561 1.9336 1.9878 8.8554 1.820710102 TSFM Ts translation elongation factor, mitochondrial 1.03561059E-11 2.67647477E-10 2.8691 1.6745 0.7739 1.0105 1.3339 0.9996 1.07306461 SHB Src homology 2 domain containing adaptor protein B 4.01815843E-05 0.000149379025 2.8675 2.5673 3.0574 1.9005 2.0005 2.2018 2.0141138162 C9orf116 chromosome 9 open reading frame 116 0.00218582408 0.005616562744 2.8669 0.2272 0.4587 0.5326 0.4179 0.1710 0.648923769 FLRT1 fibronectin leucine rich transmembrane protein 1 0.01700852109 0.034279693078 2.8663 0.0104 0.0241 0.1097 0.0898 0.0238 0.16278350 HIST1H3A histone cluster 1, H3a 4.83016125E-06 2.1738105E-05 2.8661 3.0283 0.7608 1.0616 2.3292 0.7271 1.284711343 MGLL monoglyceride lipase 0.00086753212 0.002444340308 2.8659 0.2443 0.2272 0.4728 0.3361 0.3111 0.46362271 FH fumarate hydratase 1.94373836E-09 2.07090305E-08 2.8656 2.6871 2.4461 1.3889 2.4689 3.1107 2.363410005 ACOT8 acyl-CoA thioesterase 8 3.23573589E-06 1.5063278E-05 2.8651 2.8221 0.4044 3.2741 0.6282 0.3038 0.9301283219 KCTD21 potassium channel tetramerisation domain containing 21 5.09550494E-09 4.78689287E-08 2.8630 3.1734 1.4609 4.0533 1.6039 1.8480 2.92304704 NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 6.41691216E-12 1.85815878E-10 2.8622 0.2879 3.4654 1.2772 0.6941 3.0347 0.431955718 POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) 2.52185798E-13 1.61813867E-11 2.8603 2.8450 1.9537 1.6409 2.5135 2.5699 2.5199200734 SPRED2 sprouty-related, EVH1 domain containing 2 9.23991663E-05 0.000319575538 2.8600 1.0906 0.7769 1.0729 0.7724 0.8863 1.42231978 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.17373817E-06 6.02261834E-06 2.8595 1.7875 1.7712 2.1853 1.6517 2.1218 2.623029894 CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 9.55484316E-15 1.61653791E-12 2.8554 0.8512 1.8313 1.0937 0.6396 1.9020 0.91079054 NFS1 NFS1 cysteine desulfurase 1.09356587E-07 7.17215921E-07 2.8532 4.1111 0.6088 5.8931 6.8952 0.3923 5.5755119 ADD2 adducin 2 (beta) 0.00048492969 0.001435618177 2.8517 0.6785 0.6666 0.7858 0.6424 0.7693 1.0190

8402 SLC25A11 1.39010053E-10 2.17651387E-09 2.8510 6.6861 2.5630 2.0400 4.2814 1.3930 1.887855168 MRPS18A mitochondrial ribosomal protein S18A 5.31881984E-14 5.25326898E-12 2.8499 2.0443 2.2876 2.1750 1.6509 2.7625 2.163356548 CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 2.03402316E-08 1.60890351E-07 2.8475 1.8469 2.7954 2.5825 1.4247 2.7352 2.895229933 GPR132 G protein-coupled receptor 132 3.31181529E-11 6.7537376E-10 2.8470 0.8013 1.2379 1.6717 0.8079 1.2497 1.3188100132111 LOC100132111 uncharacterized LOC100132111 0.00213800761 0.005509191246 2.8464 2.3354 2.3275 2.3002 1.2030 1.5522 2.0413124976 SPNS2 spinster homolog 2 (Drosophila) 0.00122043567 0.003329819396 2.8460 0.5671 1.4684 0.4372 0.2638 0.6026 0.2894

9645 MICAL2 2.18941341E-05 8.5572111E-05 2.8458 0.3380 0.5425 0.9174 0.3916 0.5606 0.511822993 HMGXB3 HMG box domain containing 3 2.64386052E-15 6.95977011E-13 2.8451 0.3251 0.3710 0.1579 0.4313 0.4093 0.20296950 TCP1 t-complex 1 1.15318186E-09 1.32772142E-08 2.8444 1.6480 5.1764 2.0634 1.3958 10.3674 3.16581801 DPH1 DPH2 homolog (S. cerevisiae) 3.68701016E-11 7.36273767E-10 2.8444 0.7447 1.2051 0.7424 0.7819 1.6238 0.809455621 TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) 1.66010405E-11 3.89505467E-10 2.8420 1.2439 1.4382 0.9732 1.4227 3.1649 1.37925188 PET112 PET112 homolog (yeast) 1.67387081E-07 1.05283881E-06 2.8398 0.7813 0.8454 1.0732 0.7299 0.9423 1.07799900 SV2A synaptic vesicle glycoprotein 2A 2.93597248E-10 4.16183779E-09 2.8397 1.1493 1.4941 1.0768 0.6625 1.1242 0.9133

10197 PSME3 1.41208487E-11 3.42730016E-10 2.8394 1.9470 1.7914 1.1769 2.5244 2.3308 1.437723395 LARS2 leucyl-tRNA synthetase 2, mitochondrial 8.15616349E-07 4.33225056E-06 2.8389 1.8096 2.7956 1.9629 1.3515 3.3141 2.1544729993 SHISA9 hypothetical protein LOC729993 0.00066924516 0.001920598008 2.8388 0.0512 0.3677 0.3840 0.1466 0.1505 0.363956894 AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 1.60216898E-13 1.14803261E-11 2.8388 0.5600 0.9096 0.4946 0.7373 1.1584 0.544851155 HN1 hematological and neurological expressed 1 7.89900015E-13 3.63230412E-11 2.8382 1.9915 1.6268 1.4570 1.8624 2.1964 1.589754496 PRMT7 protein arginine methyltransferase 7 9.24283018E-11 1.55511043E-09 2.8376 0.3335 0.1516 0.2314 0.2689 0.1488 0.19939632 SEC24C SEC24 family member C 4.25368055E-13 2.36961131E-11 2.8352 2.3625 2.2433 2.7692 2.3184 2.9534 3.24098209 C21orf33 chromosome 21 open reading frame 33 1.04690961E-11 2.69804405E-10 2.8345 1.5181 2.4708 1.8757 1.1987 3.1348 2.303857333 RCN3 reticulocalbin 3, EF-hand calcium binding domain 0.00157651605 0.004190587904 2.8344 0.6820 2.2537 1.1719 0.6416 1.3377 0.819380775 TMEM177 transmembrane protein 177 4.91256738E-06 2.20817789E-05 2.8339 2.2038 2.0676 2.0532 1.7405 1.7868 2.241055001 TTC22 tetratricopeptide repeat domain 22 0.00054386378 0.001593271796 2.8329 1.4905 2.6085 2.2825 1.9375 3.3669 2.296510098 TSPAN5 tetraspanin 5 1.64055774E-09 1.79498629E-08 2.8323 2.8044 2.3753 2.1393 2.3175 2.7256 2.368850814 NSDHL NAD(P) dependent steroid dehydrogenase-like 5.1711411E-07 2.87194803E-06 2.8314 2.1944 1.3945 1.6720 0.5789 1.4815 0.951951116 MRPS2 mitochondrial ribosomal protein S2 3.13615025E-10 4.39161395E-09 2.8304 1.1965 5.7960 0.8371 0.7200 49.9767 0.5807100533107 RTEL1-TNFRSF6RTEL1-TNFRSF6B readthrough (NMD candidate) 0.00174814799 0.004592029906 2.8300 0.1425 0.2277 0.1928 0.2348 0.1847 0.24905830 PEX5 peroxisomal biogenesis factor 5 6.12713143E-10 7.73169513E-09 2.8299 1.7227 2.5640 2.0418 1.4012 2.3849 1.66231723 DHODH dihydroorotate dehydrogenase (quinone) 1.92844076E-06 9.45437874E-06 2.8294 1.4289 2.3095 1.6256 1.2059 3.6752 1.5179146540 ZNF785 zinc finger protein 785 5.22572369E-06 2.33458247E-05 2.8284 1.3104 2.6891 1.9605 0.9871 2.8709 2.475991039 DPP9 dipeptidyl-peptidase 9 5.36289109E-11 9.98886299E-10 2.8283 1.8424 4.1773 1.9907 2.4560 6.7377 2.720590522 YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 1.54855779E-08 1.26055176E-07 2.8273 1.0862 1.0714 1.4685 0.8730 1.5801 1.5405126789 PUSL1 pseudouridylate synthase-like 1 5.71895807E-14 5.44663211E-12 2.8253 0.3321 0.3321 0.3321 0.3970 0.3970 0.397056342 PPAN peter pan homolog (Drosophila) 4.270372E-06 1.93714591E-05 2.8252 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970220323 OAF OAF homolog (Drosophila) 0.00117050703 0.003207484177 2.8246 1.8952 2.0261 1.4293 1.3428 1.7706 1.167164118 DUS1L dihydrouridine synthase 1-like (S. cerevisiae) 5.81082426E-10 7.39898125E-09 2.8239 0.9546 1.6572 1.3944 0.6111 2.1030 1.362257486 NLN neurolysin (metallopeptidase M3 family) 5.02312103E-05 0.000183125434 2.8236 2.3860 5.6444 1.2670 2.2685 6.3021 0.6679

2590 GALNT2 2.03706358E-09 2.15151594E-08 2.8219 0.5818 1.0479 0.6467 0.4628 0.8893 0.8621255231 MCOLN2 mucolipin 2 0.00022826971 0.000725633972 2.8218 1.4637 2.8096 1.6454 1.3120 2.2532 1.7097

55624 POMGNT1 2.74631413E-10 3.94812366E-09 2.8217 0.4476 0.7411 0.8690 0.4947 0.6766 0.75955426 POLE polymerase (DNA directed), epsilon, catalytic subunit 1.92354883E-09 2.05418376E-08 2.8216 1.2651 6.0117 1.3200 1.3064 2.4739 0.875923509 POFUT1 protein O-fucosyltransferase 1 8.76012368E-08 5.88907211E-07 2.8212 0.7825 8.7611 5.0710 0.9703 7.7201 3.1750339175 METTL2A methyltransferase like 2A 1.59103966E-11 3.76559297E-10 2.8199 1.6239 1.6476 1.6381 1.2738 2.6705 1.876457455 REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 7.92028548E-11 1.36270674E-09 2.8194 0.6314 0.9722 0.6417 0.5566 1.0589 0.7611201294 UNC13D unc-13 homolog D (C. elegans) 1.93066134E-13 1.3212376E-11 2.8190 1.4336 2.8324 1.3838 1.4087 3.4532 1.930126470 SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.00266409718 0.00671240811 2.8188 0.5380 1.5853 0.6008 0.7249 0.8007 0.5631255374 MBLAC1 similar to hypothetical protein MGC49416 2.14558642E-05 8.40209067E-05 2.8184 2.2737 2.6811 1.7415 2.4547 4.7722 2.490090326 THAP3 THAP domain containing, apoptosis associated protein 3 8.42004324E-09 7.31926879E-08 2.8184 1.3079 1.3325 1.2986 0.9705 1.7521 1.6719256815 C10orf67 chromosome 10 open reading frame 67 0.00283568545 0.007090959969 2.8175 1.7877 2.3012 1.7453 1.2815 1.7552 1.4732100506930 LINC00665 long intergenic non-protein coding RNA 665 0.00279296873 0.00699563051 2.8149 1.1455 1.2810 0.7519 1.9395 1.0377 0.73778844 KSR1 kinase suppressor of ras 1 1.01035267E-07 6.68156495E-07 2.8136 0.1011 0.4038 0.8593 0.1180 0.2481 0.4558677814 SNORA31 small nucleolar RNA, H/ACA box 31 0.0003023867 0.00093934203 2.8135 0.7512 2.7814 1.1640 0.5290 1.7144 0.76793712 IVD isovaleryl-CoA dehydrogenase 6.21661081E-09 5.6653323E-08 2.8134 0.8499 1.1918 0.9142 0.4959 1.6226 0.85199903 KLHL21 kelch-like family member 21 1.77805014E-09 1.92239835E-08 2.8129 2.6591 2.4412 2.0754 1.9672 2.7292 2.5887

6884 TAF13 6.33627579E-05 0.00022665707 2.8114 2.5565 1.6777 1.4705 1.9646 1.9922 1.4081100287902 LGALS8-AS1 LGALS8 antisense RNA 1 0.01915408802 0.038012761623 2.8110 2.3489 8.5207 1.5820 3.8076 4.5143 2.63925834 PYGB phosphorylase, glycogen; brain 5.90833128E-14 5.51739711E-12 2.8104 1.7827 2.1142 1.6165 1.6614 3.7647 2.621954606 DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 2.07861811E-09 2.19130692E-08 2.8091 1.8125 2.9153 2.0456 1.7731 5.0167 2.19879416 DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 2.85456343E-14 3.54820293E-12 2.8089 3.9947 5.0039 2.0755 3.1429 5.2293 2.223910435 CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 0.0001469823 0.000486532705 2.8052 1.6219 1.1030 1.3830 1.2820 0.8303 1.26455710 PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.93988118E-15 6.00491023E-13 2.8043 1.9614 1.9695 1.6964 1.8050 3.4621 2.1644811 CALR calreticulin 3.8058543E-10 5.17030258E-09 2.8015 2.0267 4.5025 2.1903 2.0707 6.0461 2.89239824 ARHGAP11A Rho GTPase activating protein 11A 7.19564536E-08 4.95025723E-07 2.8013 2.5042 2.7859 1.4546 2.6274 3.2446 2.656939 ACAT2 acetyl-CoA acetyltransferase 2 3.35579938E-08 2.49358139E-07 2.8005 0.7442 1.8870 1.0176 0.7218 1.6390 0.669727242 TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.00326568376 0.008043558784 2.8005 0.9679 2.1663 1.4173 0.5926 2.7161 1.4607

4150 MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 1.02690432E-12 4.4149637E-11 2.8003 1.4244 2.8710 1.4358 0.5971 7.3437 4.48035210 PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.00736613583 0.01650650403 2.7998 0.5598 1.3813 1.1825 0.3979 0.9374 1.2436126792 B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 3.90374449E-14 4.40303822E-12 2.7997 0.3163 13.8813 1.8255 1.3719 6.2739 2.304710113 PREB prolactin regulatory element binding 2.48162374E-14 3.14890479E-12 2.7992 1.8006 1.4956 1.6902 1.2959 2.7999 1.95833303 HSPA1A heat shock 70kDa protein 1A 2.89082538E-08 2.18721165E-07 2.7976 0.3321 0.3321 0.3321 0.3970 0.3970 0.39705471 PPAT phosphoribosyl pyrophosphate amidotransferase 2.08008148E-08 1.64036465E-07 2.7975 0.8138 2.2248 2.6044 0.5813 3.7409 3.815329916 SNX11 sorting nexin 11 7.47555133E-12 2.07904526E-10 2.7970 1.4278 1.8166 1.4539 1.3591 2.2711 1.5968195828 ZNF367 zinc finger protein 367 1.04544683E-06 5.42527818E-06 2.7957 3.2317 3.0841 0.9685 3.2949 3.3940 2.367257415 C3orf14 chromosome 3 open reading frame 14 0.00223038067 0.005716582361 2.7926 0.0402 0.0876 0.2223 0.5168 0.4665 0.197190485 ZNF835 zinc finger protein 835 0.00010929223 0.000372363902 2.7906 1.1064 2.4525 0.9369 0.9361 2.2173 0.940757722 IGDCC4 immunoglobulin superfamily, DCC subclass, member 4 0.02538723265 0.048480754423 2.7904 0.6876 0.7992 0.7622 0.5716 0.7072 0.418264207 IRF2BPL interferon regulatory factor 2 binding protein-like 7.39305915E-12 2.06536755E-10 2.7904 2.1871 2.0958 2.8001 1.5362 3.7411 2.722863898 SH2D4A SH2 domain containing 4A 0.00020267766 0.000651191533 2.7902 1.5838 1.4251 1.0727 1.3772 1.4006 1.02826650 CAPN15 calpain 15 3.21737054E-11 6.60621421E-10 2.7885 0.7460 0.6961 1.3380 0.5503 0.8917 2.06786607 SMN2 survival of motor neuron 2, centromeric 7.35549218E-11 1.28677062E-09 2.7885 0.2274 0.2139 0.2814 0.3592 0.2307 0.297351053 GMNN geminin, DNA replication inhibitor 3.91751982E-07 2.24743869E-06 2.7882 2.9858 3.6011 1.9433 2.7032 4.3093 2.330381618 ITM2C integral membrane protein 2C 9.06950736E-07 4.76749248E-06 2.7877 0.6455 1.1552 0.9512 0.7019 1.1869 0.997051530 ZC3HC1 zinc finger, C3HC-type containing 1 7.95160532E-10 9.62834543E-09 2.7875 0.6465 0.6933 0.7468 0.8935 1.1656 0.94905106 PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.51404437E-07 1.51057609E-06 2.7872 0.5542 0.7850 1.6318 0.4685 0.5027 0.914323005 MAPKBP1 mitogen-activated protein kinase binding protein 1 5.25081906E-10 6.78042162E-09 2.7856 1.0393 1.1176 1.2813 0.8104 1.1640 1.08349564 BCAR1 breast cancer anti-estrogen resistance 1 0.01408780653 0.029142126213 2.7829 0.2339 0.3430 0.3637 0.2109 0.2637 0.373923034 SAMD4A sterile alpha motif domain containing 4A 9.50564797E-06 4.01032555E-05 2.7825 0.7506 1.3601 1.1249 0.4678 1.2794 1.23989686 VGLL4 vestigial-like family member 4 3.72531056E-11 7.41491009E-10 2.7809 1.0491 1.0301 0.9208 0.9226 1.0067 0.904023187 PHLDB1 pleckstrin homology-like domain, family B, member 1 0.00377812702 0.009167853515 2.7809 0.3336 0.3415 0.3658 0.3549 0.2608 0.43915886 RAD23A RAD23 homolog A (S. cerevisiae) 2.53145748E-13 1.61813867E-11 2.7799 1.1351 2.9492 2.3996 1.0261 4.4852 2.765451005 AMDHD2 amidohydrolase domain containing 2 1.39174596E-06 7.03457323E-06 2.7788 1.3488 0.9466 1.0919 0.8101 1.3192 1.196790203 SNX21 sorting nexin family member 21 0.00081597293 0.002308680292 2.7762 0.9237 1.4529 1.5524 0.6536 0.8337 1.327183746 L3MBTL2 l(3)mbt-like 2 (Drosophila) 4.49070812E-11 8.62820387E-10 2.7759 2.4631 1.9315 1.9498 2.1740 2.5874 2.143590861 HN1L hematological and neurological expressed 1-like 1.75032689E-10 2.64823219E-09 2.7749 0.9050 1.6504 1.2888 0.5583 1.3899 0.94989927 MFN2 mitofusin 2 7.7376216E-13 3.57928663E-11 2.7749 2.7517 2.4861 1.9126 2.3571 2.2524 2.17882063 NR2F6 nuclear receptor subfamily 2, group F, member 6 5.28276009E-07 2.92770981E-06 2.7745 0.9714 3.1287 0.7682 0.6368 2.4931 1.12748366 HIST1H4B histone cluster 1, H4b 9.65043922E-08 6.41210274E-07 2.7744 2.9347 2.9446 2.5158 2.8983 2.1677 2.233956848 SPHK2 sphingosine kinase 2 5.10713185E-08 3.63527515E-07 2.7727 1.1406 1.3384 2.0448 1.2825 0.9834 1.86282184 FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.41385449E-06 1.1570291E-05 2.7702 0.6738 0.8356 1.0504 0.5753 0.7389 1.082060528 ELAC2 elaC ribonuclease Z 2 4.66453409E-16 2.93897817E-13 2.7693 0.6178 0.7391 0.5767 0.7117 0.9657 0.616027079 RPUSD2 RNA pseudouridylate synthase domain containing 2 5.50125687E-12 1.65055773E-10 2.7687 2.1212 1.1938 2.4590 1.9187 1.6317 2.5785

84679 SLC9A7 9.78163701E-09 8.36359717E-08 2.7677 2.4353 2.9628 1.7672 1.8251 2.4577 2.206951081 MRPS7 mitochondrial ribosomal protein S7 1.15739397E-10 1.88316141E-09 2.7667 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970284352 PPP1R37 hypothetical protein LOC284352 1.24018816E-08 1.0328495E-07 2.7665 2.0488 5.0427 1.7547 1.7932 8.3709 2.396081929 SEH1L SEH1-like (S. cerevisiae) 2.3220457E-11 5.10570626E-10 2.7640 1.7206 1.4275 1.6654 1.5751 1.9836 3.268355670 PEX26 peroxisomal biogenesis factor 26 4.41381003E-12 1.385724E-10 2.7632 2.2644 2.7304 2.4558 1.9585 3.1319 3.1516

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11

microtubule associated monooxygenase, calponin and LIM domain containing 2

proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)

protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)

TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa

solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7

4521 NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 1.74267351E-07 1.09011059E-06 2.7620 0.4730 0.4341 0.8190 0.2617 0.1490 0.7859211 ALAS1 aminolevulinate, delta-, synthase 1 1.57723056E-14 2.3817485E-12 2.7595 1.4635 2.0467 2.4447 0.9554 1.5798 2.027084971 ATG4D ATG4 autophagy related 4 homolog D (S. cerevisiae) 2.06600851E-06 1.00532909E-05 2.7594 1.1259 1.1881 1.5461 1.0391 0.9491 1.385657217 TTC7A tetratricopeptide repeat domain 7A 5.3386686E-13 2.81118596E-11 2.7586 0.9687 0.7649 1.3866 0.4577 0.5386 1.1884100133050 LOC100133050 glucuronidase, beta pseudogene 0.00573504359 0.013261290365 2.7583 0.0524 0.0120 0.2126 0.2038 0.2541 0.152855238 SLC38A7 solute carrier family 38, member 7 1.89872781E-06 9.32873204E-06 2.7564 1.3451 2.6521 1.4093 1.0832 2.5233 0.9564271 AMPD2 adenosine monophosphate deaminase 2 6.31200969E-09 5.73796225E-08 2.7561 0.7937 1.4580 1.1589 0.5656 1.3802 0.93915575 PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 8.12291477E-08 5.51344349E-07 2.7556 0.7588 1.0892 0.9821 0.7209 1.0689 0.62269392 TGFBRAP1 transforming growth factor, beta receptor associated protein 1 2.99433403E-09 3.02111935E-08 2.7544 1.1921 1.7223 1.0798 0.9213 1.4667 0.9593

6778 STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.4510861E-12 8.59620829E-11 2.7544 1.2157 1.9147 1.4630 1.1529 2.0442 1.494479017 GGCT gamma-glutamylcyclotransferase 3.93394053E-11 7.73745547E-10 2.7543 1.0714 1.2257 1.0930 0.9934 2.0807 1.20819188 DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 8.09606335E-08 5.4993037E-07 2.7527 1.8742 2.1555 1.6621 1.6947 3.9143 2.5825641 BLM Bloom syndrome, RecQ helicase-like 1.57141509E-07 9.93525829E-07 2.7526 1.9708 3.5297 2.4751 1.5240 3.3797 2.9174

9015 TAF1A 6.0268186E-06 2.649741E-05 2.7524 1.2160 1.7952 1.1846 1.0877 2.1544 1.29319423 NTN1 netrin 1 4.44385089E-05 0.000163804808 2.7516 1.4077 1.4543 1.9398 0.9124 1.5480 2.076523176 SEPT8 septin 8 6.77344293E-09 6.11483939E-08 2.7515 1.0812 0.9410 1.4665 0.8172 0.9654 1.38309454 HOMER3 homer homolog 3 (Drosophila) 0.00171310304 0.004509698719 2.7502 0.1694 0.4697 0.4411 0.1682 0.1981 0.341351042 ZNF593 zinc finger protein 593 6.9806671E-09 6.24636382E-08 2.7501 1.5247 2.0045 1.5843 0.9733 3.1717 1.55759853 RUSC2 RUN and SH3 domain containing 2 0.00010452725 0.000357931395 2.7496 0.8153 0.7686 0.8259 0.9789 0.4954 0.87057410 VAV2 vav 2 guanine nucleotide exchange factor 4.65958879E-05 0.000170998205 2.7482 0.9537 1.6561 0.6439 0.7268 1.7524 0.9521

6392 SDHD 1.08747263E-13 8.49158113E-12 2.7467 2.5461 4.4591 4.6807 0.1880 0.8562 0.786991875 TTC5 tetratricopeptide repeat domain 5 2.80979044E-07 1.6701526E-06 2.7462 2.1841 1.8388 1.3076 1.9001 2.7163 1.419984865 CCDC142 hypothetical protein FLJ14397 2.97438951E-07 1.75883641E-06 2.7458 1.0056 0.2861 1.1950 1.3749 0.0799 0.61984162 MCAM melanoma cell adhesion molecule 3.26937364E-05 0.000123221937 2.7452 0.3289 0.4826 0.9621 0.3477 0.2603 0.83129114 ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 3.81579398E-06 1.75225402E-05 2.7443 1.1782 0.9900 1.2984 1.4395 1.6282 1.7118150197 LINC00896 long intergenic non-protein coding RNA 896 0.00627641603 0.014347888616 2.7429 1.9058 1.8345 2.1514 1.9154 2.4274 2.26505296 PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.45158692E-12 5.81653427E-11 2.7415 2.3486 2.8136 2.4565 2.3658 2.3881 2.83291798 DPAGT1 diphthamide biosynthesis 1 9.35464337E-10 1.10795067E-08 2.7396 2.0715 2.7491 2.4538 1.9327 3.6252 2.743128952 CCDC22 coiled-coil domain containing 22 5.20632435E-13 2.74942077E-11 2.7394 2.2812 1.4843 1.7689 1.9733 1.4952 1.407455093 WDYHV1 WDYHV motif containing 1 8.38993423E-06 3.58347074E-05 2.7388 2.1411 2.5938 3.4917 1.1943 1.7537 2.178626277 TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.93188863E-10 4.15927555E-09 2.7388 2.3563 2.4137 2.4413 1.9383 3.8558 2.5948100131193 KIAA1984-AS1 KIAA1984 antisense RNA 1 6.65990878E-05 0.000237350991 2.7383 2.1437 3.5884 2.9003 1.5410 3.1146 1.66879055 PRC1 protein regulator of cytokinesis 1 1.69024909E-05 6.76840485E-05 2.7383 2.1213 2.6982 1.8009 1.8743 2.7247 2.6688494143 CHAC2 ChaC, cation transport regulator homolog 2 (E. coli) 3.77166814E-06 1.73357339E-05 2.7380 3.3392 1.9627 1.6313 3.6749 2.3990 1.70752580 GAK cyclin G associated kinase 2.57649943E-15 6.92320554E-13 2.7371 0.4039 0.3192 1.0023 0.6655 0.1916 1.123055300 PI4K2B Q8TCG2,G5E9Z4,phosphatidylinositol 4-kinase type 2 beta 1.10763502E-08 9.3556709E-08 2.7369 1.0148 1.0447 0.6479 1.1403 1.8177 1.04689258 MFHAS1 malignant fibrous histiocytoma amplified sequence 1 2.06747373E-10 3.07129106E-09 2.7355 2.1399 0.9623 1.3962 1.8974 0.9713 1.477955706 NDC1 NDC1 transmembrane nucleoporin 2.22266437E-06 1.07298609E-05 2.7324 2.6739 2.2709 1.4992 2.1756 2.3886 2.526457673 BEND3 KIAA1553 5.29806211E-06 2.36343239E-05 2.7312 0.8886 1.4825 1.6493 0.6494 1.1031 1.93585434 POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 3.48789672E-13 2.02320155E-11 2.7306 1.4456 1.9206 2.4224 1.2406 1.9638 1.9479

51204 TACO1 1.29435531E-10 2.04848356E-09 2.7299 2.1622 1.8962 2.2993 1.8088 2.0868 2.108210942 PRSS21 protease, serine, 21 (testisin) 1.58482914E-05 6.38263125E-05 2.7290 0.0963 1.7279 0.5814 0.3775 1.6268 0.396610101 NUBP2 nucleotide binding protein 2 6.82090817E-14 6.16988287E-12 2.7286 0.9631 3.8053 1.8544 0.9299 15.2807 4.0860100529211 TMEM256-PLSC TMEM256-PLSCR3 readthrough (NMD candidate) 0.00035439091 0.001081943324 2.7276 0.3321 0.3321 0.3321 0.3970 0.3970 0.397051588 PIAS4 protein inhibitor of activated STAT, 4 1.07092735E-11 2.74831243E-10 2.7255 1.8580 1.8155 1.7026 1.2826 1.9938 2.336322827 PUF60 poly-U binding splicing factor 60KDa 7.99793605E-13 3.65345719E-11 2.7247 0.7974 0.9838 1.2356 0.7255 0.9838 1.092910060 ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.00017098685 0.000557606952 2.7242 0.8832 0.8996 0.5592 0.6647 0.4142 0.336584172 POLR1B polymerase (RNA) I polypeptide B, 128kDa 6.58089004E-10 8.20791965E-09 2.7232 1.7956 1.5251 1.6350 1.9576 2.0305 2.856655038 CDCA4 cell division cycle associated 4 1.43324053E-08 1.17805537E-07 2.7197 1.8298 2.4326 1.9545 1.6066 3.4536 3.156423566 LPAR3 lysophosphatidic acid receptor 3 0.01887786398 0.037542155026 2.7196 0.3549 0.5704 0.7189 0.4373 0.1908 0.70735576 PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 5.64912923E-14 5.43267839E-12 2.7194 1.7378 2.2376 1.6807 1.2633 3.5904 1.9630124935 SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.00368675267 0.008966370936 2.7187 0.8515 1.1005 1.0936 0.6012 1.0808 0.84016120 RPE ribulose-5-phosphate-3-epimerase 7.71473434E-07 4.11822507E-06 2.7186 1.1004 0.9390 1.1276 1.0136 1.3626 1.0899728833 FAM72D family with sequence similarity 72, member D 0.0001136887 0.000385975448 2.7184 1.0690 2.4946 1.8894 0.9802 3.3005 2.58887368 UGT8 UDP glycosyltransferase 8 0.00569602026 0.013182084807 2.7178 0.3849 0.4130 0.4642 0.4352 0.2795 0.376427173 SLC39A1 solute carrier family 39 (zinc transporter), member 1 4.53910495E-10 6.00134049E-09 2.7178 4.9503 2.4525 2.5355 3.8774 2.0802 2.4380374383 NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 9.96759975E-05 0.000342603429 2.7170 1.6191 2.5841 1.9856 1.4638 1.8188 1.47133161 HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00121713038 0.003321793329 2.7152 4.0031 8.2506 1.2279 2.0330 5.7515 2.4287638 BIK BCL2-interacting killer (apoptosis-inducing) 5.67300946E-06 2.51290252E-05 2.7148 1.7936 1.9438 1.6787 1.2002 1.5475 1.7839348262 FAM195B hypothetical protein LOC348262 7.96097902E-09 6.9766431E-08 2.7148 1.8100 5.9261 2.1264 1.3594 4.0693 3.08667917 BAG6 BCL2-associated athanogene 6 8.60281796E-14 7.24381059E-12 2.7136 0.5694 0.9920 0.8094 0.4456 0.6189 0.60642643 GCH1 GTP cyclohydrolase 1 1.18745857E-09 1.36118212E-08 2.7128 1.5207 1.7368 1.3350 1.6445 2.2084 2.674351253 MRPL37 mitochondrial ribosomal protein L37 1.36857372E-09 1.53954057E-08 2.7123 1.9290 2.2761 4.0660 0.3752 2.1382 3.011423144 ZC3H3 zinc finger CCCH-type containing 3 6.17291701E-16 3.41792544E-13 2.7122 1.2900 1.4484 2.1543 1.1649 1.9906 2.44319179 AP4M1 adaptor-related protein complex 4, mu 1 subunit 3.44383603E-07 2.00400548E-06 2.7119 0.7653 0.9353 0.5027 0.7600 0.2227 0.313910869 USP19 ubiquitin specific peptidase 19 5.39406286E-16 3.08000989E-13 2.7111 0.7596 1.1902 1.3072 0.7132 1.0929 1.160163910 SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 0.00069201901 0.001980976245 2.7109 1.0787 1.8716 2.1248 0.5549 2.1593 1.44266484 ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 3.32705706E-06 1.54726359E-05 2.7094 0.2078 0.9660 0.4818 0.3590 0.3844 0.2971

26133 TRPC4AP 2.1109698E-15 6.32321969E-13 2.7080 0.6645 0.6534 0.7663 0.6267 0.6284 0.745930817 EMR2 egf-like module containing, mucin-like, hormone receptor-like 2 0.00012017291 0.000405877883 2.7069 0.2188 0.2622 0.3616 0.5548 0.2427 0.36355036 PA2G4 proliferation-associated 2G4, 38kDa 9.47390312E-10 1.11898615E-08 2.7068 1.7556 2.4083 1.8954 1.4999 3.7283 2.60745714 PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 5.7405162E-12 1.70831779E-10 2.7068 2.4748 1.2081 1.5655 1.7441 1.7441 1.5154116225 ZMYND19 zinc finger, MYND-type containing 19 6.59549295E-08 4.57657774E-07 2.7058 1.7393 1.0162 2.1048 0.8870 1.4644 2.953483595 SOX7 SRY (sex determining region Y)-box 7 0.01053946034 0.022613553239 2.7057 0.5566 1.9809 0.8429 0.5531 1.2892 0.65242597 GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.90275236E-09 2.93682675E-08 2.7053 1.7063 2.5159 1.7878 1.2794 4.3936 3.199855622 TTC27 tetratricopeptide repeat domain 27 6.50911222E-08 4.52566585E-07 2.7052 2.2939 2.9198 2.2696 2.6651 4.5202 2.724554984 PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 7.10211477E-06 3.08022409E-05 2.7051 0.3321 0.3321 0.3321 0.3970 0.3970 0.397053841 CDHR5 cadherin-related family member 5 0.01352084711 0.028115729868 2.7050 0.0805 0.0447 0.1306 0.0568 0.1979 0.12749363 RAB33A RAB33A, member RAS oncogene family 9.58113859E-08 6.37300926E-07 2.7044 2.9713 3.6928 1.6722 3.6747 4.7687 2.8046727866 FAM156B family with sequence similarity 156, member B 0.00012723596 0.000427677607 2.7039 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

6610 SMPD2 3.38426976E-06 1.57266982E-05 2.7033 2.2204 5.3060 0.9172 2.8871 2.4201 0.6935114088 TRIM9 tripartite motif containing 9 0.00231792815 0.005920210117 2.7033 1.3595 2.2144 2.0901 1.4712 3.0495 1.6800

10598 AHSA1 1.11203256E-09 1.28439057E-08 2.7014 3.4751 3.0515 1.5272 3.0391 9.3511 2.425265999 LRRC61 leucine rich repeat containing 61 1.09801576E-07 7.1961779E-07 2.7006 1.0535 1.0431 1.3806 0.8463 0.6775 0.79379986 RCE1 Ras converting CAAX endopeptidase 1 9.22842577E-10 1.09565819E-08 2.6999 1.5642 1.9734 1.8192 1.7817 3.6875 2.650625885 POLR1A polymerase (RNA) I polypeptide A, 194kDa 2.48026614E-08 1.91140544E-07 2.6984 1.0672 4.0569 0.3993 3.8730 9.7084 0.19872950 GSTP1 glutathione S-transferase pi 1 8.38112499E-08 5.66765047E-07 2.6975 1.2815 1.7299 1.7888 0.9813 2.4805 1.574680308 FLAD1 flavin adenine dinucleotide synthetase 1 3.81659812E-11 7.56251034E-10 2.6972 1.3468 1.3058 1.3454 0.9737 1.7894 1.422784306 PDCD2L programmed cell death 2-like 2.88895153E-09 2.92610434E-08 2.6954 1.2021 2.1225 1.6899 1.0776 2.5978 2.03495055 SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.01401667334 0.029008115907 2.6942 0.0513 0.1065 0.1788 0.1460 0.0406 0.160853838 C11orf24 chromosome 11 open reading frame 24 3.104414E-08 2.32474806E-07 2.6940 1.2842 2.0545 2.3719 0.9230 2.5541 3.359584275 SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 4.62951339E-08 3.33164509E-07 2.6935 1.2968 1.2202 1.6866 0.9483 0.9944 1.650254541 DDIT4 DNA-damage-inducible transcript 4 5.17681486E-08 3.68057436E-07 2.6933 2.0394 3.3561 1.5177 2.3925 4.3587 3.44542879 GPX4 glutathione peroxidase 4 1.13565534E-10 1.84943801E-09 2.6930 1.3142 1.9893 1.2348 1.1720 1.9819 1.55847126 TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 3.21778166E-11 6.60621421E-10 2.6927 0.6409 10.2574 0.9459 0.6535 1.5376 1.2079

7035 TFPI 0.00668698081 0.015176315164 2.6921 1.0923 1.0704 0.7008 0.6116 0.8588 0.37054967 OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 4.21139616E-12 1.33827184E-10 2.6916 1.1619 1.4845 1.1933 0.9439 1.6624 1.16659091 PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 5.09048306E-09 4.78689287E-08 2.6916 0.4836 1.5658 0.6472 0.4301 1.6849 0.620710755 GIPC1 GIPC PDZ domain containing family, member 1 3.5516078E-11 7.13916146E-10 2.6906 1.0462 1.1454 1.7952 0.8975 1.1607 1.69634074 M6PR mannose-6-phosphate receptor (cation dependent) 1.54592074E-12 6.0793321E-11 2.6863 2.3317 2.6957 2.1641 2.6112 5.0972 3.73978602 NOP14 NOP14 nucleolar protein 1.34968195E-11 3.31470278E-10 2.6839 1.5208 1.2639 3.2403 0.9566 2.0510 2.903279902 NUP85 nucleoporin 85kDa 3.47375363E-10 4.7903718E-09 2.6826 1.7424 0.9797 1.0704 1.7154 1.7264 1.445910058 ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 3.91872201E-05 0.000146158172 2.6823 0.2662 0.7361 0.3891 0.4186 0.4082 0.3522284106 CISD3 hypothetical protein LOC284106 2.78728708E-11 5.94183488E-10 2.6822 1.5625 3.4482 2.0743 1.2662 3.6727 2.22149260 PDLIM7 PDZ and LIM domain 7 (enigma) 1.35564637E-06 6.87683798E-06 2.6816 0.5221 0.7458 1.0784 0.3223 1.1497 1.294127346 TMEM97 transmembrane protein 97 4.05827711E-07 2.31387501E-06 2.6803 1.8708 1.7004 2.0577 1.2258 2.1630 2.265726262 TSPAN17 tetraspanin 17 8.23295237E-14 6.99686073E-12 2.6785 1.3825 0.5542 2.1573 0.9094 0.4730 1.68054609 MYC v-myc avian myelocytomatosis viral oncogene homolog 3.44057305E-07 2.00274453E-06 2.6779 2.4903 3.3071 1.7184 2.9644 6.4071 3.155410081 PDCD7 programmed cell death 7 5.28417117E-10 6.81867059E-09 2.6775 2.1584 2.3025 1.8500 2.4679 4.0729 2.1971

1650 DDOST 5.87844446E-11 1.07410937E-09 2.6771 2.2544 1.9938 2.1439 1.8958 2.5975 3.1280440957 SMIM4 small integral membrane protein 4 4.77122774E-07 2.67587088E-06 2.6768 2.2105 3.4734 2.4895 1.8145 6.1398 2.60976941 TCF19 transcription factor 19 4.83254746E-06 2.17434886E-05 2.6762 0.3519 0.4020 0.7817 0.4424 0.4171 0.91773070 HELLS helicase, lymphoid-specific 1.02444806E-05 4.29722564E-05 2.6749 2.3870 3.3180 1.8598 2.3295 3.2847 2.628511285 B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 1.6664115E-09 1.82109276E-08 2.6724 1.0549 1.6872 1.1287 0.8502 1.7455 1.149179683 ZDHHC14 zinc finger, DHHC-type containing 14 9.38194947E-06 3.96362961E-05 2.6697 0.5116 0.9002 0.7609 0.7021 0.9280 1.2365

84892 POMGNT2 7.35768431E-07 3.94945968E-06 2.6694 0.7859 1.3924 0.8753 0.6135 1.1494 0.9329348926 FAM86EP hypothetical protein LOC348926 8.88728337E-06 3.77384247E-05 2.6684 1.1845 1.3623 1.4527 1.1668 1.6423 2.04297226 TRPM2 transient receptor potential cation channel, subfamily M, member 2 0.00598252281 0.013758672975 2.6678 0.4226 0.4644 0.4456 0.2761 0.3806 0.355726517 TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 1.26346919E-10 2.01625406E-09 2.6668 1.6175 2.9120 1.6888 1.6301 5.4131 3.0432158 ADSL adenylosuccinate lyase 1.77214939E-11 4.12493167E-10 2.6653 1.0740 1.3319 1.2138 1.0729 1.7739 1.689851649 MRPS23 mitochondrial ribosomal protein S23 7.30290261E-10 8.95561318E-09 2.6653 3.1312 3.9366 1.7200 2.9256 6.1071 2.47775818 PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 7.09980501E-06 3.0799534E-05 2.6648 2.0024 7.5126 1.1781 1.1399 4.7149 1.211630834 ZNRD1 zinc ribbon domain containing 1 1.21759953E-11 3.02693586E-10 2.6638 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702966 GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa 2.08033707E-09 2.19130692E-08 2.6634 2.1319 4.6657 1.8382 1.9147 7.1939 2.18878772 FADD Fas (TNFRSF6)-associated via death domain 8.38198784E-14 7.09054082E-12 2.6631 2.6343 1.3977 1.3747 2.4504 1.9870 2.20709703 KIAA0100 KIAA0100 3.76301232E-13 2.14198632E-11 2.6624 2.0459 2.6463 2.3154 1.7284 2.1007 2.459023193 GANAB glucosidase, alpha; neutral AB 8.46061461E-13 3.81833826E-11 2.6603 1.5115 2.0590 1.3972 0.9311 2.2665 1.73383675 ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 2.09727399E-06 1.01891493E-05 2.6545 4.4676 1.3029 2.2435 2.5052 0.4657 1.386480228 ORAI2 ORAI calcium release-activated calcium modulator 2 5.66315901E-07 3.11772345E-06 2.6545 2.2330 2.1697 2.6800 1.4456 2.3644 2.719023649 POLA2 polymerase (DNA directed), alpha 2, accessory subunit 1.20378599E-08 1.00620209E-07 2.6545 1.0668 1.0613 1.3555 0.9197 1.5897 1.373154487 DGCR8 DGCR8 microprocessor complex subunit 8.14885693E-12 2.22564894E-10 2.6543 1.7242 1.7135 1.0540 1.4029 2.0831 1.127684706 GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 0.0002278342 0.000724375589 2.6541 0.6229 1.1589 0.7857 0.4053 1.2882 0.90695833 PCYT2 phosphate cytidylyltransferase 2, ethanolamine 6.15794929E-08 4.30608685E-07 2.6539 1.0016 1.7973 1.0128 0.9069 1.0890 0.95441892 ECHS1 epithelial cell transforming 2 1.05152589E-10 1.73720444E-09 2.6537 1.3351 1.5995 1.4555 0.7120 1.5040 1.8277

TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa

succinate dehydrogenase complex, subunit D, integral membrane protein

translational activator of mitochondrially encoded cytochrome c oxidase I

transient receptor potential cation channel, subfamily C, member 4 associated protein

sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)

AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)

protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)

10135 NAMPT nicotinamide phosphoribosyltransferase 8.62598885E-06 3.67398761E-05 2.6526 1.6968 2.1777 1.9896 1.3516 2.5420 3.085780742 PRR3 proline rich 3 1.07207886E-06 5.55559414E-06 2.6514 0.3321 0.3321 0.3321 0.3970 0.3970 0.39705373 PMM2 phosphomannomutase 2 8.75839738E-12 2.3260674E-10 2.6512 9.3159 3.0505 3.3750 6.9736 8.2595 2.614026150 RIBC2 RIB43A domain with coiled-coils 2 0.01377676663 0.028550423036 2.6507 0.0560 1.1527 0.3107 0.0573 1.7320 1.036511117 EMILIN1 elastin microfibril interfacer 1 0.00050678408 0.001494747158 2.6479 0.2317 0.2735 0.6883 0.2888 0.1452 0.3981127281 FAM213B family with sequence similarity 213, member B 2.66806937E-12 9.19829499E-11 2.6468 1.3432 2.5496 1.7581 0.9803 4.6501 2.59364713 NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 6.20867536E-11 1.12425139E-09 2.6466 1.7731 3.3914 1.1990 1.2522 4.2427 2.17499024 BRSK2 BR serine/threonine kinase 2 0.00089308739 0.002508993351 2.6455 0.2311 0.2530 0.3579 0.1928 0.1506 0.4368677681 SCARNA20 small Cajal body-specific RNA 20 0.00362751442 0.008835236413 2.6452 0.0986 0.1183 0.3385 0.0926 0.0775 0.20498846 ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 2.14260602E-07 1.31198717E-06 2.6448 0.9724 0.2549 1.5098 0.5806 0.2660 0.540348 ACO1 aconitase 1, soluble 5.50677746E-08 3.8804411E-07 2.6435 2.3627 2.2117 2.4607 1.8120 2.0416 2.671151004 COQ6 coenzyme Q6 monooxygenase 1.44995254E-05 5.88091739E-05 2.6432 1.1622 1.3975 0.9448 2.3871 0.4023 0.964155076 TMEM45A transmembrane protein 45A 0.00010532794 0.000360335531 2.6424 0.5889 0.4984 0.5906 0.4445 0.3803 0.55052821 GPI glucose-6-phosphate isomerase 9.92695554E-08 6.57669803E-07 2.6424 0.9256 0.6912 1.0315 1.0444 1.1401 1.030357546 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 3.85416068E-10 5.22302976E-09 2.6419 1.4513 2.2888 1.8681 1.4228 2.6912 2.25362034 EPAS1 endothelial PAS domain protein 1 0.01050568919 0.022551686192 2.6410 0.8515 2.0070 1.1248 0.6624 1.9923 1.1325145741 C2CD4A nuclear localized factor 1 0.00994309058 0.02152353407 2.6408 2.1264 1.5785 2.6598 1.1831 1.0593 1.2896221468 TMEM217 chromosome 6 open reading frame 128 0.00440191448 0.010511210317 2.6407 1.3810 2.5948 2.8908 0.8666 1.1115 1.479464428 NARFL nuclear prelamin A recognition factor-like 1.30517666E-10 2.05942901E-09 2.6392 0.6133 1.2260 0.8628 0.4944 0.8100 0.927584079 ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 3.47149491E-13 2.02320155E-11 2.6385 1.8177 3.0340 2.0894 0.3572 1.0591 1.508979894 ZNF672 zinc finger protein 672 7.38604593E-12 2.06536755E-10 2.6370 1.8311 3.4199 1.8640 1.7347 3.8425 2.43778566 PDXK pyridoxal (pyridoxine, vitamin B6) kinase 1.38389531E-10 2.16865652E-09 2.6370 1.1091 2.7141 1.5316 1.1461 2.5512 2.048851162 EGFL7 EGF-like-domain, multiple 7 0.00026760503 0.000841146211 2.6356 0.2500 0.3634 0.3223 0.1023 0.4755 0.2371124359 CDYL2 chromodomain protein, Y-like 2 2.95895428E-08 2.22768903E-07 2.6354 0.7925 2.2747 2.0099 0.9323 3.7943 1.6050123099 DEGS2 delta(4)-desaturase, sphingolipid 2 0.00836461924 0.018472120219 2.6351 1.2757 1.8038 1.3750 0.5602 1.7958 1.40982976 GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 8.3090643E-15 1.53356791E-12 2.6348 1.2628 1.2052 1.0035 1.5256 1.8882 1.4498285074 LOC285074 hypothetical protein LOC285074 4.51158211E-09 4.31600148E-08 2.6347 0.8046 0.7545 0.7055 1.1023 1.1055 1.75309144 SYNGR2 synaptogyrin 2 3.12815546E-11 6.48045993E-10 2.6318 1.3165 2.1811 1.8410 0.9250 2.2653 2.2483677774 SCARNA1 small Cajal body-specific RNA 1 3.02500565E-06 1.41834496E-05 2.6310 0.4976 0.8740 0.6105 0.3645 0.5038 0.375710635 RAD51AP1 RAD51 associated protein 1 4.01603371E-05 0.000149330419 2.6308 0.6784 0.3692 2.0553 0.9333 0.3852 1.075554753 ZNF853 zinc finger protein 853 0.00011173836 0.000380060197 2.6303 0.8629 2.0197 1.0590 0.3603 3.4516 0.885829952 DPP7 dipeptidyl-peptidase 7 2.14277613E-12 7.81493122E-11 2.6303 1.4493 2.4769 1.0817 1.3112 2.9311 1.2270140885 SIRPA signal-regulatory protein alpha 0.01563869832 0.03188100277 2.6297 0.2910 0.6539 0.7171 0.2870 0.5783 0.5032199731 CADM4 cell adhesion molecule 4 0.00177426232 0.004651933018 2.6287 0.6388 0.8097 1.1825 0.4073 0.3558 1.103122997 IGSF9B immunoglobulin superfamily, member 9B 4.98200152E-05 0.00018173514 2.6283 0.7743 1.9015 1.3850 0.4655 2.0620 1.2424401106 LINC00884 long intergenic non-protein coding RNA 884 0.00904679358 0.019801510822 2.6274 1.9463 1.5388 2.1065 1.6175 1.7529 2.1414114548 NLRP3 NLR family, pyrin domain containing 3 0.00358580382 0.008746470085 2.6260 1.7170 1.2216 1.4540 1.1553 0.7712 0.9273

51025 PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 3.16374417E-05 0.000119635624 2.6253 1.7791 1.8909 1.4697 0.8106 3.1560 1.402657505 AARS2 alanyl-tRNA synthetase 2, mitochondrial (putative) 3.46864325E-09 3.4314591E-08 2.6251 1.0421 1.3934 1.1628 0.9134 1.8365 1.01682107 ETF1 eukaryotic translation termination factor 1 1.91564856E-09 2.04934019E-08 2.6237 1.2477 1.0813 1.0902 1.1766 1.6442 1.3931246330 PELI3 pellino homolog 3 (Drosophila) 7.65698086E-08 5.23217481E-07 2.6231 1.1350 1.1155 1.9227 1.0265 1.3879 1.51853984 LIMK1 LIM domain kinase 1 6.45125843E-08 4.48714861E-07 2.6229 0.6467 0.9232 1.2186 0.3176 0.7961 0.944729934 SNX12 sorting nexin 12 1.10286259E-07 7.22535149E-07 2.6203 1.0044 1.1644 0.8529 1.1857 1.6993 1.58382644 GCHFR GTP cyclohydrolase I feedback regulator 1.42149483E-12 5.73367626E-11 2.6200 2.4514 2.3321 2.1966 1.7909 1.9073 2.465979000 AUNIP chromosome 1 open reading frame 135 0.0006184814 0.001789815049 2.6194 2.3215 2.0170 2.3551 1.8361 3.1019 2.159726747 NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 7.45438292E-06 3.22153464E-05 2.6183 0.6177 5.5476 2.3039 0.2799 8.4477 0.59498533 COPS3 COP9 signalosome subunit 3 4.79274181E-11 9.10255189E-10 2.6176 2.2646 2.1598 1.9292 1.7064 2.7094 2.044656652 C10orf2 progressive external ophthalmoplegia 1 4.95729732E-09 4.68528355E-08 2.6151 0.2869 1.0186 0.3722 0.3760 0.3016 0.29705119 CHMP1A charged multivesicular body protein 1A 7.65988543E-13 3.55232047E-11 2.6143 0.1714 0.2526 0.2192 0.2608 0.2157 0.2414401565 FAM166A family with sequence similarity 166, member A 0.00053215782 0.001563529121 2.6128 0.0267 0.0329 0.1588 0.1328 0.0835 0.23813008 HIST1H1E histone cluster 1, H1e 9.87452135E-08 6.54670734E-07 2.6120 2.2642 7.0625 1.5801 2.4377 4.8208 1.338829780 PARVB parvin, beta 7.96022912E-05 0.000279817827 2.6118 0.4414 0.7519 1.0427 0.3220 0.8270 0.757684957 RELT RELT tumor necrosis factor receptor 7.64303647E-09 6.73029216E-08 2.6117 0.5287 0.4528 0.6002 0.4482 0.4911 0.849979155 TNIP2 TNFAIP3 interacting protein 2 1.42921953E-09 1.59235971E-08 2.6107 0.8640 2.1041 1.7956 0.5598 2.1130 1.25152314 FLII flightless I homolog (Drosophila) 1.74783262E-14 2.55951107E-12 2.6097 1.7154 2.2485 1.5852 1.2829 2.7611 1.66488501 SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 1.50048898E-06 7.52798866E-06 2.6086 1.6825 1.5189 2.0846 1.2038 1.7937 2.76477153 TOP2A topoisomerase (DNA) II alpha 170kDa 1.08154714E-05 4.50879064E-05 2.6038 1.0290 0.8751 1.0809 0.9087 0.8661 1.319254821 ERCC6L excision repair cross-complementation group 6-like 0.00034604856 0.001060372169 2.6030 1.3195 0.4222 1.8712 1.1882 0.4036 2.1527150468 CKAP2L cytoskeleton associated protein 2-like 0.00070459596 0.002015400347 2.6025 1.2437 0.8688 2.1013 1.2625 1.0939 2.345323409 SIRT4 sirtuin 4 0.00020404736 0.000655016392 2.6022 1.6291 1.2671 1.5018 1.6883 1.8593 1.52471737 DLAT dihydrolipoamide S-acetyltransferase 4.24741655E-11 8.2387256E-10 2.6021 2.4270 2.3502 1.9803 2.4109 3.5289 2.723755735 DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 3.38885302E-07 1.97509139E-06 2.6013 1.3009 1.0968 1.2231 0.7371 2.2507 1.304064782 AEN interferon stimulated exonuclease gene 20kDa-like 1 3.0889367E-09 3.09905582E-08 2.5999 1.7056 1.7354 1.7502 1.3369 2.4352 1.545480176 SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.9024129E-05 0.000110577332 2.5991 0.3464 0.5928 0.5306 0.2779 0.4643 0.723583759 RBM4B RNA binding motif protein 4B 2.72756895E-10 3.92471143E-09 2.5985 3.6851 2.0267 1.9769 3.3353 2.2920 2.041757171 DOLPP1 dolichyldiphosphatase 1 8.90807628E-11 1.50711454E-09 2.5985 1.2583 1.9811 2.2155 1.0743 1.8891 2.767280700 UBXN6 UBX domain protein 6 1.20550825E-16 1.3744062E-13 2.5977 0.7409 1.4889 1.1580 0.4405 1.4674 1.223084174 SLA2 Src-like-adaptor 2 9.39978451E-10 1.11238901E-08 2.5959 1.8198 1.9200 2.2605 1.6055 2.0425 2.4385

6774 STAT3 1.39577206E-11 3.40662978E-10 2.5958 2.8310 1.7488 2.4470 2.7609 2.7597 3.152323020 SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 3.45447152E-14 4.04950077E-12 2.5947 1.3802 1.2703 1.7799 1.5930 2.0186 1.924085415 RHPN2 rhophilin, Rho GTPase binding protein 2 0.00407347968 0.009808990596 2.5944 0.2748 0.7472 0.6866 0.4511 0.5357 0.596784433 CARD11 caspase recruitment domain family, member 11 4.17500199E-13 2.34725035E-11 2.5926 1.2895 1.4147 1.6658 1.0486 2.5737 2.0855283742 FAM98B family with sequence similarity 98, member B 5.91411518E-09 5.42755965E-08 2.5924 2.1422 1.9655 1.3604 1.7007 1.6693 1.9283

79156 PLEKHF1 1.42680451E-09 1.59063892E-08 2.5921 1.6810 2.3059 2.1442 1.7948 2.8103 2.4407653238 GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) 7.51276843E-10 9.17602305E-09 2.5916 1.1702 1.0367 1.0410 1.2186 1.3720 0.985764151 NCAPG non-SMC condensin I complex, subunit G 0.0004344658 0.001299273179 2.5913 0.2416 0.5568 0.9613 0.5641 4.0726 1.50507156 TOP3A topoisomerase (DNA) III alpha 3.9837626E-10 5.36413487E-09 2.5899 0.8601 0.9706 1.6781 0.7626 1.2024 1.586679968 WDR76 WD repeat domain 76 1.80845314E-06 8.92359055E-06 2.5895 2.3906 2.0494 1.7837 1.5623 1.8200 1.683551075 TMX2 thioredoxin-related transmembrane protein 2 8.87004459E-10 1.05698674E-08 2.5893 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

8818 DPM2 6.65467936E-10 8.28863676E-09 2.5890 1.0167 0.8267 0.9477 0.9113 1.2008 1.276910227 MFSD10 major facilitator superfamily domain containing 10 4.55315831E-10 6.01556823E-09 2.5890 0.2228 1.8023 2.3058 0.1929 0.8803 1.5324131408 FAM131A family with sequence similarity 131, member A 1.9472421E-06 9.53887603E-06 2.5877 0.7824 0.5141 0.8026 0.8536 0.4233 0.6700116840 CNTROB centrobin, centrosomal BRCA2 interacting protein 4.51953852E-09 4.32135049E-08 2.5872 0.8450 1.7972 1.0059 0.6898 0.5203 0.767310421 CD2BP2 CD2 (cytoplasmic tail) binding protein 2 1.90157759E-15 5.99062512E-13 2.5870 2.7047 1.4989 2.0763 2.4808 2.1152 2.0457

10610 ST6GALNAC2 0.0124767123 0.026194931311 2.5868 1.1532 1.8576 1.1951 0.7305 1.3240 0.915083451 ABHD11 abhydrolase domain containing 11 7.21359465E-05 0.000255390044 2.5867 1.2268 2.4316 1.5516 1.2228 2.8540 2.178225929 GEMIN5 gem (nuclear organelle) associated protein 5 1.30286049E-10 2.05933105E-09 2.5862 2.0762 2.5593 1.9307 1.6954 3.5711 2.19773292 HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 9.69116163E-09 8.29400025E-08 2.5854 0.2158 0.3166 0.4574 0.1290 0.2628 0.3512

4522 MTHFD1 9.85321547E-08 6.53732582E-07 2.5852 2.2379 3.1902 1.5329 2.0342 4.8574 2.320884461 NEURL4 neuralized homolog 4 (Drosophila) 1.07649358E-11 2.75485864E-10 2.5849 0.6427 1.2400 0.9352 0.7628 1.4075 1.0783

2547 XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 7.46547831E-13 3.4976723E-11 2.5845 4.4349 3.7095 1.7649 2.4705 7.9185 1.1039692205 SNORD89 small nucleolar RNA, C/D box 89 0.00015083515 0.000497663387 2.5837 0.2310 0.8240 1.2850 0.6788 0.4642 0.40878078 USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.35240811E-13 9.96419395E-12 2.5814 1.6710 2.4319 1.6598 1.9668 4.7500 2.41518368 HIST1H4L histone cluster 1, H4l 1.85944579E-05 7.37321908E-05 2.5813 2.2044 1.5332 1.9006 1.4808 1.0068 1.039157410 SCYL1 SCY1-like 1 (S. cerevisiae) 8.95777026E-15 1.58061002E-12 2.5812 1.1876 1.1563 1.3411 0.8250 0.9450 1.103755748 CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 4.11397781E-10 5.50297237E-09 2.5811 2.1365 2.5488 2.0951 1.8612 3.2980 2.452657168 ASPHD2 aspartate beta-hydroxylase domain containing 2 4.48670116E-06 2.02822869E-05 2.5806 2.1152 2.2673 2.2602 2.0422 2.2755 2.723650615 IL21R interleukin 21 receptor 2.00321977E-10 2.98554907E-09 2.5801 1.3007 1.4260 2.0709 1.2105 1.4378 2.131779180 EFHD2 EF-hand domain family, member D2 2.13675096E-08 1.67997907E-07 2.5792 1.6585 1.5373 1.4363 1.6939 2.0111 1.73918600 TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.00938825515 0.020467986897 2.5787 0.4424 1.0108 0.8514 0.5589 0.6863 0.68469394 HS6ST1 heparan sulfate 6-O-sulfotransferase 1 2.57770207E-09 2.64456891E-08 2.5779 1.3347 1.9931 1.6256 1.1013 3.1492 1.920610939 AFG3L2 AFG3-like AAA ATPase 2 1.42044424E-10 2.21642674E-09 2.5774 1.6418 2.3897 2.2216 1.3346 1.9653 2.7722440695 ETV3L ets variant 3-like 0.00403218962 0.009723659591 2.5766 0.0712 0.1295 0.3692 0.2496 0.2727 0.319679363 RSG1 REM2 and RAB-like small GTPase 1 3.60030661E-05 0.000134915509 2.5761 2.4153 2.6151 2.6037 1.5191 1.5563 1.757563920 C5orf54 transposon-derived Buster3 transposase-like 0.0117531835 0.02488749206 2.5751 2.3636 2.0108 1.5868 2.1314 2.1005 1.61509061 PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 3.34859384E-10 4.65528668E-09 2.5749 2.7522 2.3046 1.5755 2.3298 2.8650 2.0373138151 NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 9.31302446E-11 1.56266211E-09 2.5737 0.8367 3.4248 2.0004 0.4794 2.3199 1.9258390916 NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 1.27037922E-09 1.44715518E-08 2.5736 1.6871 2.3590 2.5688 1.2257 2.3373 2.78708407 TAGLN2 transgelin 2 3.2782484E-11 6.70223979E-10 2.5727 1.6410 2.0180 2.3292 1.6279 2.8789 2.53828604 SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 1.74538894E-09 1.89268526E-08 2.5708 1.8267 3.0595 1.7998 1.5538 3.5589 2.0174

219855 SLC37A2 solute carrier family 37 (glycerol-3-phosphate transporter), member 2 0.02473645819 0.047438261026 2.5695 0.7630 0.9901 0.6799 0.9316 0.6184 0.49203024 HIST1H1A histone cluster 1, H1a 0.0047642371 0.011282029598 2.5693 1.0710 0.9835 1.2607 0.9748 0.4345 0.9265114790 STK11IP serine/threonine kinase 11 interacting protein 5.22381395E-10 6.75032026E-09 2.5675 2.0489 1.5046 1.6813 2.0319 1.7591 1.9301124093 CCDC78 coiled-coil domain containing 78 0.00212962143 0.005491453968 2.5669 0.2096 0.2377 0.4645 0.1443 0.1924 0.293179626 TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2 9.37104691E-07 4.907646E-06 2.5646 0.3321 0.3321 0.3321 0.3970 0.3970 0.39709767 PHF16 jade family PHD finger 3 0.00219916075 0.005645249538 2.5641 1.8547 1.1201 0.7833 1.1120 0.6665 0.841349856 WRAP73 WD repeat containing, antisense to TP73 5.26887435E-12 1.59923688E-10 2.5628 1.7751 2.5847 1.8070 0.9605 2.9555 1.351610534 SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 8.59533545E-08 5.79962959E-07 2.5626 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970134353 LSM11 LSM11, U7 small nuclear RNA associated 1.8975778E-05 7.5146384E-05 2.5624 1.6493 2.2566 1.9583 1.1347 2.8366 1.901551374 ATRAID all-trans retinoic acid-induced differentiation factor 4.19999734E-09 4.05193582E-08 2.5585 1.7003 0.2862 1.2694 3.9294 0.2105 0.64409040 UBE2M ubiquitin-conjugating enzyme E2M 2.65376816E-12 9.1853835E-11 2.5585 5.8884 3.1646 1.8855 3.7725 6.9465 2.74845066 PAM peptidylglycine alpha-amidating monooxygenase 4.92561676E-09 4.66325749E-08 2.5579 0.2597 0.4539 0.3706 0.2878 0.2342 0.2992124056 NOXO1 NADPH oxidase organizer 1,NADPH oxidase organizer 1 0.00437518332 0.01045284382 2.5571 0.1354 0.2061 0.1839 0.0720 0.2642 0.33379131 AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 3.23392452E-09 3.22545136E-08 2.5565 1.2182 0.8023 1.3373 1.2833 1.6051 1.5802113189 CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 4.43275733E-08 3.21155202E-07 2.5556 1.2556 1.5376 1.3703 1.1242 1.1820 1.299823596 OPN3 opsin 3 4.40639285E-05 0.000162522427 2.5549 1.8122 1.1034 1.2597 1.4011 1.3532 1.83396836 SURF4 surfeit 4 6.68341988E-10 8.3187635E-09 2.5548 2.1424 1.9923 1.6709 1.1733 1.8168 1.896378992 YIPF2 Yip1 domain family, member 2 3.39097537E-10 4.69749068E-09 2.5548 0.1708 0.6567 2.2621 0.1650 0.2450 0.84746048 RNF5 ring finger protein 5, E3 ubiquitin protein ligase 5.57200307E-12 1.66631162E-10 2.5504 0.5298 0.3899 1.0118 0.5392 0.4195 0.71469129 PRPF3 pre-mRNA processing factor 3 4.02030246E-11 7.87563963E-10 2.5503 1.0470 0.8930 0.7467 1.5289 1.3626 1.22294913 NTHL1 nth endonuclease III-like 1 (E. coli) 2.6688494E-10 3.85660468E-09 2.5495 0.7600 0.3792 1.8445 0.1420 0.4937 0.425251388 NIP7 NIP7, nucleolar pre-rRNA processing protein 4.75426199E-11 9.03952915E-10 2.5494 0.1271 2.9395 2.2181 0.4109 1.2826 0.41527205 TRIP6 thyroid hormone receptor interactor 6 3.38893426E-08 2.51615631E-07 2.5487 1.1957 1.7659 1.8206 0.9596 2.3276 1.737584279 PRADC1 protease-associated domain containing 1 6.72229554E-08 4.65617074E-07 2.5482 2.2990 2.8036 1.5835 1.3029 2.8127 1.264456907 SPIRE1 spire-type actin nucleation factor 1 1.17373126E-05 4.85322868E-05 2.5477 0.6925 0.4062 0.5409 0.4097 0.3411 0.5227

signal transducer and activator of transcription 3 (acute-phase response factor)

pleckstrin homology domain containing, family F (with FYVE domain) member 1

dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase

22879 MON1B MON1 secretory trafficking family member B 2.87239573E-11 6.08867921E-10 2.5460 1.7482 2.0302 1.0548 2.2419 2.1921 1.738422937 SCAP SREBF chaperone 9.38458338E-12 2.46726773E-10 2.5460 1.7524 3.0313 1.3868 1.3151 3.7824 1.84319638 FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.01523870113 0.031183956449 2.5455 1.0114 1.1669 1.4265 0.7326 0.7344 0.994285014 TMEM141 transmembrane protein 141 3.88642436E-06 1.78155409E-05 2.5446 1.3926 1.0468 1.8666 1.0517 2.1417 1.96761025 CDK9 cyclin-dependent kinase 9 1.16379676E-09 1.33909915E-08 2.5438 1.8038 11.7751 5.2139 0.9032 5.2235 4.316981691 exonuclease NEF-sp 0.00309355303 0.007673719273 2.5438 0.0657 0.3032 4.8640 0.0801 0.2880 1.785464699 TMPRSS3 transmembrane protease, serine 3 0.00243318651 0.006187777853 2.5431 0.4356 0.4213 0.5110 0.4700 0.4534 0.33395928 RBBP4 retinoblastoma binding protein 4 2.20133628E-14 3.00170273E-12 2.5429 2.2907 4.3090 2.2757 1.2545 5.7631 2.724410721 POLQ polymerase (DNA directed), theta 0.00021070659 0.000674497336 2.5410 1.3073 1.0402 0.8715 1.1139 1.1596 1.109783959 SLC4A11 solute carrier family 4, sodium borate transporter, member 11 0.01770670376 0.035526176686 2.5407 1.1566 1.4331 1.2929 1.0841 1.5051 1.303110873 ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.00531755265 0.0124121515 2.5387 1.1103 1.6842 1.1846 1.1480 1.0732 1.197523378 RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 2.39506908E-08 1.85199756E-07 2.5385 17.1207 4.9105 2.8456 2.8604 1.5889 1.7254100287042 LOC100287042 uncharacterized LOC100287042 0.00020846502 0.000668141191 2.5363 1.1257 3.3460 1.4389 0.3536 4.7628 0.983084937 ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 3.52445491E-05 0.00013229014 2.5362 1.6602 1.4165 1.5552 0.8013 1.1563 1.3577112858 TP53RK TP53 regulating kinase 6.91007875E-08 4.77176715E-07 2.5357 1.9340 1.4432 1.9516 1.9788 2.3171 2.53774125 MAN2B1 mannosidase, alpha, class 2B, member 1 4.62308234E-12 1.43174509E-10 2.5356 1.2031 6.7434 0.7891 0.4123 3.1027 1.20003139 HLA-L major histocompatibility complex, class I, L (pseudogene) 0.00014332553 0.000476190897 2.5344 0.4615 0.4965 0.5707 0.5133 0.5960 0.682011165 NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 3.48391375E-06 1.61527714E-05 2.5342 2.9425 2.4693 1.6622 1.9881 3.4834 2.31672079 ERH enhancer of rudimentary homolog (Drosophila) 8.67897605E-12 2.31701372E-10 2.5342 3.3591 20.2030 1.4942 1.1628 16.2546 1.160923759 PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 8.51387222E-09 7.38526649E-08 2.5334 0.6496 0.5812 0.8121 0.8063 1.4379 1.322757143 ADCK1 aarF domain containing kinase 1 0.00029148386 0.000907788148 2.5332 0.5871 1.2013 0.7715 0.5615 1.0987 0.860010262 SF3B4 splicing factor 3b, subunit 4, 49kDa 3.0029787E-10 4.2370986E-09 2.5321 2.2877 2.9858 1.7969 1.9696 3.4970 1.546355170 PRMT6 protein arginine methyltransferase 6 3.414185E-08 2.5307906E-07 2.5317 1.0593 2.0651 1.6797 1.3655 2.1837 2.80688193 DPF1 D4, zinc and double PHD fingers family 1 0.00605484226 0.01390923785 2.5316 0.4113 0.9139 1.4519 0.2274 0.4743 1.057354862 CC2D1A coiled-coil and C2 domain containing 1A 2.39608537E-13 1.58055133E-11 2.5310 2.1228 1.1154 1.5000 0.2972 1.8572 2.20709907 AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 8.34037262E-11 1.42097327E-09 2.5304 1.2620 1.5231 1.1874 1.7755 2.0926 1.7294163259 DENND2C DENN/MADD domain containing 2C 0.0070485878 0.015888452548 2.5300 1.9224 1.6429 1.9846 1.7987 1.8617 1.769023154 NCDN neurochondrin 6.76416703E-12 1.92815694E-10 2.5298 0.3321 0.3321 0.3321 0.3970 0.3970 0.397025923 ATL3 atlastin GTPase 3 3.32293895E-10 4.62780035E-09 2.5294 0.7669 0.6296 0.7728 0.7306 0.7474 0.888555003 PAK1IP1 PAK1 interacting protein 1 3.085564E-08 2.3125277E-07 2.5285 4.0630 3.4693 1.0890 1.9856 2.8673 0.40705768 QSOX1 quiescin Q6 sulfhydryl oxidase 1 8.49083385E-12 2.281537E-10 2.5283 2.0311 2.6735 1.8826 1.7123 3.1204 2.3029147700 KLC3 kinesin light chain 3 0.00560596556 0.012990767614 2.5282 0.2193 0.3265 0.3397 0.2646 0.2547 0.3861163154 PRR22 proline rich 22 0.00878676412 0.019290638499 2.5271 0.0029 0.0468 0.2791 0.1155 0.0660 0.1779135932 TMEM139 transmembrane protein 139 0.02090872476 0.041041234697 2.5268 0.6483 0.5657 0.6631 0.3261 0.3896 0.4319

6509 SLC1A4 0.00011205435 0.000380993125 2.5267 0.8327 1.2644 0.8512 0.5895 1.1383 1.16826821 SUOX sulfite oxidase 0.00049958514 0.001475657887 2.5263 0.4688 0.6521 0.7481 0.4659 0.6166 0.700225799 ZNF324 zinc finger protein 324 1.26471618E-12 5.14865122E-11 2.5249 1.2229 2.2548 1.8323 1.1176 3.4571 1.8960286077 FAM83H family with sequence similarity 83, member H 3.89568033E-08 2.86215806E-07 2.5246 0.2134 0.2838 0.3096 0.2625 0.2304 0.33932805 GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.01125193E-08 8.61222225E-08 2.5240 2.3425 2.2113 1.5364 1.6746 3.6654 2.1313115353 LRRC42 leucine rich repeat containing 42 6.33636604E-08 4.41395655E-07 2.5233 1.9290 2.7134 3.5842 1.1223 2.4454 2.959980346 REEP4 receptor accessory protein 4 3.29827888E-08 2.45583341E-07 2.5226 1.2808 2.8366 1.8154 0.9403 2.3619 1.395355472 RBM12B-AS1 RBM12B antisense RNA 1 0.00341345104 0.008368519701 2.5221 2.0998 5.6060 1.3103 1.1274 3.0827 0.89174851 NOTCH1 notch 1 1.74885361E-08 1.40338397E-07 2.5220 1.1001 3.0462 1.1969 1.0972 7.9475 2.24867355 SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 1.1956225E-07 7.76899511E-07 2.5214 1.4344 1.6026 1.2685 1.1152 2.7422 1.228064109 CRLF2 cytokine receptor-like factor 2 0.02001000575 0.039471318697 2.5211 0.8084 0.4273 0.7121 0.4482 0.4516 0.552755964 SEPT3 septin 3 0.00041219903 0.001241420902 2.5194 0.9899 1.7798 1.5501 0.5423 1.7076 1.452826504 CNNM4 cyclin M4 2.62599955E-08 2.01183496E-07 2.5192 1.0811 1.0905 1.1973 0.7609 0.9294 1.018184445 LZTS2 leucine zipper, putative tumor suppressor 2 2.83239218E-10 4.05591457E-09 2.5171 0.8519 0.9575 1.2112 0.8701 0.7895 1.1414

4247 MGAT2 2.16717681E-10 3.19601733E-09 2.5166 22.7077 4.8800 13.6120 19.2212 10.0507 15.5976478 ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 0.00014730777 0.000487345206 2.5153 1.1666 1.2912 1.1271 1.0863 1.5458 0.881810922 FASTK Fas-activated serine/threonine kinase 5.13801655E-09 4.81939623E-08 2.5150 1.1225 3.9893 1.6948 1.1817 4.9990 2.074754442 KCTD5 potassium channel tetramerization domain containing 5 3.90180518E-06 1.78681164E-05 2.5149 2.2798 1.5752 1.9894 1.9255 2.2883 2.736957473 ZNF512B zinc finger protein 512B 2.81875652E-08 2.13977229E-07 2.5146 1.3711 1.0785 2.2663 0.8061 0.6050 1.72173069 HDLBP high density lipoprotein binding protein 6.97387858E-14 6.2771778E-12 2.5140 0.8915 1.1580 1.0696 0.8023 1.2019 1.169354840 APTX aprataxin 3.62687605E-09 3.56291823E-08 2.5134 0.8705 1.1606 0.8419 0.9423 1.4163 0.91092987 GUK1 guanylate kinase 1 5.40167961E-09 5.03406061E-08 2.5126 0.9759 1.9966 0.8868 1.0998 1.9037 1.2748494514 C18orf56 chromosome 18 open reading frame 56 0.01683852926 0.033970807852 2.5100 0.5813 0.8119 2.1825 0.4634 1.2883 1.90265603 MAPK13 mitogen-activated protein kinase 13 4.04004499E-10 5.42791927E-09 2.5098 1.8870 1.7125 2.3371 1.4543 2.3317 1.93862305 FOXM1 forkhead box M1 0.00041649839 0.001252518174 2.5092 0.3321 0.3321 0.3321 0.3970 0.3970 0.397084641 HIATL1 hippocampus abundant transcript-like 1 9.0844165E-08 6.08023657E-07 2.5088 1.3633 0.9302 1.0773 1.3650 1.2765 1.54862180 ACSL1 acyl-CoA synthetase long-chain family member 1 0.00061250268 0.001774761965 2.5069 0.4877 0.4493 0.5521 0.4635 0.3807 0.609923 ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 5.75591276E-14 5.44932839E-12 2.5066 0.5940 0.7721 0.5694 0.6587 0.9451 0.61792678 GGT1 gamma-glutamyltransferase 1 2.40077101E-07 1.4506246E-06 2.5065 0.3234 0.3292 0.6217 0.4026 0.2443 0.371955750 AGK acylglycerol kinase 6.4927409E-10 8.12662095E-09 2.5042 2.7820 2.8847 1.9005 2.2796 3.6041 1.520280772 GLTPD1 glycolipid transfer protein domain containing 1 2.99667006E-10 4.23146487E-09 2.5036 4.2898 1.2061 0.4006 1.2660 3.7892 0.872555722 CEP72 centrosomal protein 72kDa 8.93393219E-06 3.79188871E-05 2.5036 2.6404 5.0736 2.6683 0.4146 1.1356 2.659084301 DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 1.48766563E-08 1.21731422E-07 2.5035 1.3185 1.1456 1.1328 1.0289 1.0617 1.410854888 NSUN2 NOP2/Sun RNA methyltransferase family, member 2 5.951338E-10 7.55158667E-09 2.5034 2.9841 1.0774 1.2293 1.1669 2.8322 3.713464949 MRPS26 mitochondrial ribosomal protein S26 1.90698342E-06 9.36425718E-06 2.5029 1.4245 1.3210 2.2253 1.0969 1.5232 2.68309513 FXR2 fragile X mental retardation, autosomal homolog 2 7.20931349E-11 1.26784E-09 2.5026 1.2815 1.1361 1.0738 1.4381 1.8194 2.120064859 NABP1 nucleic acid binding protein 1 1.20300053E-10 1.93667187E-09 2.5019 1.1309 1.9805 1.7051 1.1768 2.3713 1.95205693 PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.10700442E-08 9.3556709E-08 2.5017 1.8783 1.1791 1.3759 1.8223 1.9683 2.03471059 CENPB centromere protein B, 80kDa 1.26657906E-10 2.01757684E-09 2.5013 4.4149 7.3206 1.7660 7.7690 8.3208 1.049929985 SLC39A3 solute carrier family 39 (zinc transporter), member 3 5.37564457E-10 6.90743865E-09 2.5013 1.4268 1.3765 1.9437 1.0650 2.4963 2.053923313 KIAA0930 KIAA0930 6.93754725E-08 4.7889257E-07 2.5002 0.4980 0.6624 0.7772 0.3928 0.7216 0.71884595 MUTYH mutY homolog 6.24833973E-08 4.3592846E-07 2.5002 1.1932 1.4020 1.5020 0.9085 0.6337 1.214679447 PAGR1 PAXIP1 associated glutamate-rich protein 1 8.22329389E-13 3.74703307E-11 2.4995 1.6115 2.8052 1.9664 1.7436 4.2197 2.457610935 PRDX3 peroxiredoxin 3 4.16194738E-08 3.03823821E-07 2.4988 2.1224 1.2512 2.1850 2.4226 1.5641 2.596751490 C9orf114 chromosome 9 open reading frame 114 1.2756364E-10 2.02505893E-09 2.4987 2.0826 2.5723 1.5693 1.4401 2.7100 1.3935162968 ZNF497 zinc finger protein 497 0.00014635609 0.000484723307 2.4984 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706503 SLA Src-like-adaptor 1.95976892E-09 2.08433631E-08 2.4983 1.8037 1.8270 1.7632 1.4670 2.1153 1.523423016 EXOSC7 exosome component 7 3.5933189E-12 1.18301123E-10 2.4982 2.2774 1.3601 1.2495 1.2456 1.1200 0.771379918 SETD6 SET domain containing 6 2.16398327E-07 1.3220322E-06 2.4968 1.1132 1.3558 2.0232 1.0253 1.4366 2.78457284 TUFM Tu translation elongation factor, mitochondrial 1.1136396E-10 1.81844708E-09 2.4967 0.4556 0.5986 1.8549 0.7226 0.9784 0.780955295 KLHL26 kelch-like family member 26 8.4779323E-09 7.36258455E-08 2.4966 0.8904 2.2619 1.4390 0.9159 3.0748 1.711323780 APOL2 apolipoprotein L, 2 1.46670184E-08 1.20177471E-07 2.4963 2.3580 1.2263 1.8264 2.5478 1.8926 2.1270

23416 KCNH3 0.00026640756 0.000837542841 2.4949 1.6038 0.8893 1.3100 0.9775 0.4594 1.0654

123096 SLC25A29 5.4514696E-05 0.000197480675 2.4947 0.7268 1.5506 0.8420 0.7208 1.5935 1.3808142 PARP1 poly (ADP-ribose) polymerase 1 1.58696721E-12 6.18274303E-11 2.4945 2.0114 1.2236 1.9143 1.8932 1.5175 2.319225841 ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0019116832 0.004975113997 2.4940 2.1209 3.5236 2.0383 1.5471 2.8074 1.99211141 CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 0.00649609023 0.014801915528 2.4935 0.1632 0.4728 0.5804 0.2798 0.2252 0.3682286075 ZNF707 zinc finger protein 707 1.50131918E-06 7.53008621E-06 2.4926 1.7657 2.5557 1.6000 1.5358 2.6887 1.96888427 ZNF282 zinc finger protein 282 2.83665265E-07 1.68392844E-06 2.4919 0.6616 1.3458 1.2692 0.5383 1.5229 1.3819

1677 DFFB 5.86735276E-07 3.22333944E-06 2.4916 1.2482 4.1047 1.6545 0.2832 2.6539 1.59288425 LTBP4 latent transforming growth factor beta binding protein 4 7.49096553E-09 6.62832553E-08 2.4911 0.5424 0.8181 1.2339 0.5494 0.9339 0.9238145864 HAPLN3 hyaluronan and proteoglycan link protein 3 8.93640367E-07 4.70022936E-06 2.4906 1.3415 1.2914 1.6447 1.2291 2.0023 2.357857521 RPTOR regulatory associated protein of MTOR, complex 1 6.8325327E-10 8.46439166E-09 2.4895 0.9806 1.0088 0.7943 0.8817 2.0902 1.01546794 STK11 serine/threonine kinase 11 2.24259577E-11 4.98186038E-10 2.4889 1.2386 2.3621 1.5064 1.0913 2.8799 1.788484300 MNF1 mitochondrial nucleoid factor 1 3.41876555E-07 1.99131922E-06 2.4880 1.4522 1.5569 2.5326 1.6827 2.1079 2.68561643 DDB2 damage-specific DNA binding protein 2, 48kDa 1.67341589E-10 2.55230845E-09 2.4866 3.1313 2.3564 1.9933 2.3843 2.8530 2.674547 ACLY ATP citrate lyase 4.95566114E-11 9.33599085E-10 2.4856 1.8083 1.9756 1.3130 1.9364 3.5414 1.9493285855 RPL7L1 ribosomal protein L7-like 1 1.3547636E-10 2.1303133E-09 2.4851 2.8730 2.8651 1.8436 3.2817 5.5165 2.8376126321 MFSD12 major facilitator superfamily domain containing 12 7.49354655E-11 1.30330405E-09 2.4850 1.6021 2.1703 1.6944 1.0533 4.0772 2.1156896 CCND3 cyclin D3 1.5396361E-09 1.69887996E-08 2.4836 1.9870 2.8749 1.9928 2.4824 4.9272 2.35148353 HIST1H3E histone cluster 1, H3e 0.01083331178 0.023167869023 2.4834 1.8358 1.2433 1.1154 1.9067 1.1058 1.041824142 NAT6 N-acetyltransferase 6 (GCN5-related) 3.78978208E-07 2.18280817E-06 2.4827 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702941 GSTA4 glutathione S-transferase alpha 4 0.02363231334 0.045602453198 2.4820 0.9296 2.4293 1.2433 0.8850 3.3200 1.4817751071 METTL12 methyltransferase like 12 1.05787014E-05 4.41713967E-05 2.4810 2.5637 2.9847 1.8190 1.1861 1.9620 0.795186 ACTL6A actin-like 6A 9.3518673E-11 1.56768183E-09 2.4796 1.1700 1.6628 1.5860 1.7575 3.5351 2.78622647 BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 1.69220077E-08 1.36091076E-07 2.4795 0.4996 5.4584 5.8830 0.4385 2.4638 5.5456100287216 SH3RF3-AS1 SH3RF3 antisense RNA 1 0.00090616469 0.00254299512 2.4795 1.6942 1.3222 1.2422 0.8133 0.4169 0.415479038 ZFYVE21 zinc finger, FYVE domain containing 21 1.56240643E-06 7.81681904E-06 2.4791 1.2517 2.1026 1.7004 1.0105 1.0556 1.275211054 OGFR opioid growth factor receptor 4.39043157E-09 4.21555258E-08 2.4785 1.0835 0.9918 1.5801 0.8051 0.3231 0.62498985 PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 1.87550091E-09 2.01395785E-08 2.4779 9.4199 5.4303 10.8639 8.1028 3.8098 3.9517387509 GPR153 G protein-coupled receptor 153 0.00231017083 0.005902872524 2.4777 0.7486 2.8738 1.0128 0.5290 1.8606 1.2307

8518 IKBKAP 0.00018552712 0.000600629251 2.4755 11.5636 2.0076 0.7527 9.7637 2.0429 0.7278100532732 MSH5-SAPCD1 MSH5-SAPCD1 readthrough (NMD candidate) 1.27508353E-07 8.22506519E-07 2.4754 0.3675 0.3832 0.4029 0.3956 0.4263 0.449355898 UNC45A unc-45 homolog A (C. elegans) 3.02788918E-13 1.84418637E-11 2.4754 1.2093 1.6928 1.4907 0.9330 2.1084 1.594879651 RHBDF2 rhomboid 5 homolog 2 (Drosophila) 4.66876331E-06 2.10324564E-05 2.4743 0.4658 0.6737 0.8498 0.3662 0.7837 0.762250813 COPS7A COP9 signalosome subunit 7A 2.68543202E-11 5.76594757E-10 2.4737 1.8032 1.2217 1.8447 1.3496 1.3383 2.08203837 KPNB1 karyopherin (importin) beta 1 2.22991861E-11 4.96868631E-10 2.4733 0.9915 1.3174 1.1615 1.0411 1.2500 1.49588659 ALDH4A1 aldehyde dehydrogenase 4 family, member A1 0.00032579443 0.001005220493 2.4720 1.2391 1.0302 0.7860 0.7565 0.7904 0.80555230 PGK1 phosphoglycerate kinase 1 2.12986064E-07 1.30637172E-06 2.4714 2.8405 4.1823 2.0793 2.6406 6.2290 2.6315157506 RDH10 retinol dehydrogenase 10 (all-trans) 0.00042106517 0.001263956425 2.4709 0.8379 2.6015 1.2405 0.8414 2.3232 2.16313308 HSPA4 heat shock 70kDa protein 4 4.66786627E-10 6.13165007E-09 2.4705 2.1946 3.1359 1.9518 2.1719 5.0304 3.866510570 DPYSL4 dihydropyrimidinase-like 4 0.00061692072 0.00178587609 2.4704 1.1567 6.3297 1.4913 0.7341 2.8450 1.151525896 INTS7 integrator complex subunit 7 8.67829237E-11 1.47369664E-09 2.4703 0.3911 4.1513 0.5913 1.4379 5.1236 0.43396184 RPN1 ribophorin I 4.02696617E-09 3.91178766E-08 2.4701 1.7559 2.5300 1.4968 1.7850 2.7926 2.0500

292 SLC25A5 8.15706558E-10 9.85101799E-09 2.4684 0.9147 1.0814 1.4284 0.4655 0.7355 0.5668100500849 MIR3916 microRNA 3916 0.00015457959 0.000508915002 2.4682 0.1256 0.1019 0.2037 0.4336 0.2490 0.51786150 MRPL23 mitochondrial ribosomal protein L23 2.90343452E-08 2.19311928E-07 2.4672 1.4893 1.9413 1.7747 1.1825 3.9597 3.19138668 EIF3I eukaryotic translation initiation factor 3, subunit I 2.66022025E-11 5.72527024E-10 2.4662 0.5071 0.2372 1.4210 0.2811 0.2878 1.41863692 EIF6 eukaryotic translation initiation factor 6 5.9124875E-13 2.99771164E-11 2.4657 1.4514 2.3076 2.1276 1.6280 3.9484 2.30089463 PICK1 protein interacting with PRKCA 1 7.6521876E-07 4.09311393E-06 2.4642 1.7210 1.4681 1.3365 1.7619 1.6136 1.35242114 ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 4.46872627E-07 2.52247656E-06 2.4628 1.6843 2.1271 1.3612 1.2644 1.9241 1.6275440173 LOC440173 uncharacterized LOC440173 0.01067989846 0.02288531778 2.4626 0.0723 0.0550 0.1841 0.2308 0.1549 0.268079171 RBM42 RNA binding motif protein 42 2.59796581E-12 9.02472077E-11 2.4622 2.0134 1.9535 2.0040 1.5356 2.0364 2.3122

solute carrier family 1 (glutamate/neutral amino acid transporter), member 4

mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

potassium voltage-gated channel, subfamily H (eag-related), member 3solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29

DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein

solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5

169714 QSOX2 quiescin Q6 sulfhydryl oxidase 2 1.71806485E-09 1.86748846E-08 2.4622 1.6448 1.5292 1.9504 0.8644 1.3780 2.09306837 MED22 mediator complex subunit 22 1.01566428E-10 1.682522E-09 2.4621 8.3305 6.5388 15.8377 7.4367 5.4318 7.4966

26088 GGA1 1.79206277E-11 4.16597594E-10 2.4612 2.7387 4.7289 2.2413 1.7844 4.9591 2.081011321 GPN1 GPN-loop GTPase 1 2.70458807E-12 9.30663526E-11 2.4599 0.4514 0.4045 1.1139 0.6626 0.1483 0.488879575 ABHD8 abhydrolase domain containing 8 5.94183988E-06 2.61940246E-05 2.4596 1.1424 1.2996 2.2075 0.8509 1.7577 1.55511841 DTYMK dual specificity phosphatase 1 1.02744296E-06 5.33943055E-06 2.4595 1.5027 2.6275 2.2152 1.1346 4.1561 3.33808891 EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1.09443996E-08 9.26243954E-08 2.4592 1.9160 1.9001 2.3531 1.4746 2.3181 2.49535329 PLAUR plasminogen activator, urokinase receptor 0.02115773588 0.041462264044 2.4581 1.5213 1.2600 1.8051 1.1133 0.9389 1.19203297 HSF1 heat shock transcription factor 1 4.68838647E-12 1.44706415E-10 2.4576 2.5165 2.5907 0.9237 2.2696 14.8701 1.207064787 EPS8L2 EPS8-like 2 6.87727259E-07 3.71559801E-06 2.4571 0.3238 0.6876 0.6511 0.2679 0.5123 0.53527850 IL1R2 interleukin 1 receptor, type II 0.02119679914 0.041520727242 2.4559 0.0884 0.3691 0.5774 0.2379 0.1979 0.3595387103 CENPW chromosome 6 open reading frame 173 0.00034643329 0.001061373093 2.4552 1.8071 2.6575 1.4810 1.6786 2.1292 1.894124137 KIF4A kinesin family member 4A 0.00214997212 0.005534557713 2.4548 10.8440 5.1375 1.3311 2.8109 0.7502 0.667164834 ELOVL1 ELOVL fatty acid elongase 1 9.0273131E-13 3.99387567E-11 2.4541 2.5718 2.3501 1.9006 1.7973 3.5629 2.1459144100 PLEKHA7 pleckstrin homology domain containing, family A member 7 0.00162316891 0.004302080397 2.4519 0.5694 0.3775 0.7513 0.5028 0.3390 0.62375211 PFKL phosphofructokinase, liver 8.17153851E-09 7.1372061E-08 2.4512 0.9663 1.3363 0.9950 0.7872 1.2505 1.21865433 POLR2D polymerase (RNA) II (DNA directed) polypeptide D 5.39489003E-08 3.81188827E-07 2.4511 2.0310 1.9392 1.8747 1.6855 3.0006 2.553551294 PCDH12 protocadherin 12 0.01084501442 0.023187468239 2.4507 0.7055 0.9074 1.3010 0.5517 0.9647 0.7252283596 SNHG10 small nucleolar RNA host gene (non-protein coding) 10 1.01492299E-06 5.28037383E-06 2.4505 3.0029 1.0209 7.0295 2.4313 1.5481 6.003026499 PLEK2 pleckstrin 2 0.00091935158 0.002576045397 2.4481 1.2098 0.8741 1.0322 0.9110 0.9404 0.75343980 LIG3 ligase III, DNA, ATP-dependent 1.70206103E-09 1.85561212E-08 2.4475 2.0404 2.7463 1.6425 1.5411 2.5668 1.63428726 EED embryonic ectoderm development 5.23785824E-07 2.90635122E-06 2.4456 0.8924 1.2807 0.9263 1.2529 1.6093 1.2515

6553 SLC9A5 4.64586322E-05 0.000170550156 2.4443 1.2423 2.8626 1.3194 0.4434 1.1365 1.419755009 C19orf24 chromosome 19 open reading frame 24 3.5480368E-11 7.13916146E-10 2.4439 1.0577 1.9938 1.7795 0.6699 2.2217 2.01208638 OASL 2'-5'-oligoadenylate synthetase-like 0.00737510005 0.016524565061 2.4436 3.0367 2.5005 1.6952 3.2069 1.5858 1.18169246 UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.34062845E-07 8.6041317E-07 2.4430 2.1353 2.1848 1.7336 1.9265 3.8489 2.1021100137049 PLA2G4B phospholipase A2, group IVB (cytosolic) 0.00577347867 0.013339509803 2.4430 0.0912 0.1103 0.2089 0.1265 0.0581 0.1722221908 PPP1R35 chromosome 7 open reading frame 47 2.52288825E-08 1.94016052E-07 2.4428 1.1800 1.3955 1.5895 1.1184 2.1795 2.7523348654 GEN1 hypothetical protein FLJ40869 2.50694109E-05 9.67000795E-05 2.4406 1.2470 4.8659 1.5891 0.7336 2.2407 1.1652

788 SLC25A20 1.68405423E-07 1.05851527E-06 2.4404 3.2045 2.4065 1.6625 1.9557 1.8463 1.34984735 SEPT2 septin 2 4.91410754E-12 1.50655324E-10 2.4390 3.0628 4.1856 2.6339 1.5432 4.3909 2.788910978 CLP1 cleavage and polyadenylation factor I subunit 1 6.88324007E-08 4.75682914E-07 2.4377 2.1342 1.5089 2.2849 2.3712 1.9908 2.37581181 CLCN2 chloride channel, voltage-sensitive 2 0.00046117473 0.001371514424 2.4374 0.8971 1.0036 1.1751 0.9350 1.6873 1.2821126382 NR2C2AP nuclear receptor 2C2-associated protein 4.30691435E-08 3.13404775E-07 2.4373 1.8392 2.9137 1.7722 2.3420 3.1877 2.015126873 OPLAH 5-oxoprolinase (ATP-hydrolysing) 0.00537014313 0.012515098615 2.4361 0.1439 0.5839 0.4952 0.1631 0.4345 0.47139125 RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) 7.85076158E-09 6.89341906E-08 2.4360 5.9052 11.1083 1.8340 3.5553 10.6220 1.97703992 FADS1 fatty acid desaturase 1 0.00103803261 0.002872471885 2.4358 0.1711 0.3228 0.3761 0.0840 0.1094 0.333487178 PNPT1 polyribonucleotide nucleotidyltransferase 1 9.87966013E-06 4.15564341E-05 2.4352 2.5911 1.6774 1.4387 2.7225 2.3004 1.500560314 C12orf10 chromosome 12 open reading frame 10 8.7328576E-11 1.48021126E-09 2.4340 1.2251 2.5767 2.2605 1.2584 3.8362 2.04526257 RXRB retinoid X receptor, beta 3.13652375E-10 4.39161395E-09 2.4338 0.8698 0.6931 0.7088 0.8632 0.5900 0.743358506 SCAF1 SR-related CTD-associated factor 1 3.25607125E-09 3.24399858E-08 2.4332 4.0696 3.9650 2.0500 2.9242 3.7320 3.0955605 BCL7A B-cell CLL/lymphoma 7A 5.83895984E-06 2.58140514E-05 2.4321 0.8839 2.6367 2.0267 0.6802 2.4101 2.033965082 VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 5.93927382E-12 1.75602607E-10 2.4321 2.7931 3.9920 1.9420 2.6188 5.4257 2.6386128077 LIX1L Lix1 homolog (mouse)-like 4.43999313E-09 4.25866428E-08 2.4312 1.8616 1.7689 1.6575 1.7121 1.5400 1.53704137 MAPT microtubule-associated protein tau 0.00321142549 0.007928545682 2.4307 0.5288 0.6324 0.7592 0.5392 0.5724 0.696511331 PHB2 prohibitin 2 2.29170667E-11 5.04981707E-10 2.4291 2.2981 1.3472 0.7217 0.4021 3.7421 1.112485414 SLC45A3 solute carrier family 45, member 3 0.00291545491 0.007272517686 2.4289 0.2118 0.2093 0.2839 0.2732 0.2076 0.3075

220963 SLC16A9 solute carrier family 16, member 9 (monocarboxylic acid transporter 9) 0.01278533224 0.026762927094 2.4282 0.4867 0.9922 1.3457 0.2067 0.3683 1.16996631 SNRPC small nuclear ribonucleoprotein polypeptide C 5.73964259E-11 1.05401758E-09 2.4270 1.3599 2.3200 1.5257 1.9626 4.2393 2.1476115950 ZNF653 zinc finger protein 653 4.51127372E-05 0.00016598871 2.4258 1.4102 2.6431 1.3660 1.0060 2.1686 1.58212622 GAS8 growth arrest-specific 8 4.1769839E-05 0.000154654204 2.4258 1.0461 1.0754 0.6839 0.8421 1.2746 0.545264925 CCDC71 coiled-coil domain containing 71 2.93099926E-08 2.2093737E-07 2.4236 1.8029 1.7155 2.1621 1.4437 2.1794 1.94953309 HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.44341358E-06 1.17058345E-05 2.4226 2.0935 5.1212 1.9802 2.5691 7.4327 3.114190525 SHF Src homology 2 domain containing F 0.00153995925 0.004104760811 2.4219 1.0118 1.0532 1.1666 0.9521 0.8107 1.192823098 SARM1 sterile alpha and TIR motif containing 1 2.34393725E-07 1.41909945E-06 2.4212 1.1576 0.9356 1.0373 1.0872 1.3499 1.20888542 APOL1 apolipoprotein L, 1 1.8976044E-06 9.32572016E-06 2.4204 2.7717 1.7605 2.3334 2.8117 2.4940 1.992922983 MAST1 microtubule associated serine/threonine kinase 1 0.00426133397 0.010210724715 2.4201 0.4259 0.4495 1.2020 0.5104 0.3339 0.917722904 SBNO2 strawberry notch homolog 2 (Drosophila) 2.91683918E-08 2.20142443E-07 2.4192 1.2504 2.2922 1.5790 1.0790 2.6145 1.9681388552 BLOC1S3 biogenesis of lysosome-related organelles complex-1, subunit 3 4.77932406E-07 2.67876715E-06 2.4184 3.5733 4.0951 1.5599 2.9482 5.5339 3.0961645332 FAM86C2P family with sequence similarity 86, member A pseudogene 6.8598077E-05 0.000243714576 2.4183 0.8997 2.3524 1.5024 0.8975 2.9424 2.023923075 SWAP70 SWAP switching B-cell complex 70kDa subunit 9.54397216E-06 4.02556462E-05 2.4177 2.3573 2.0262 1.4585 1.9491 1.7920 1.630684243 ZDHHC18 zinc finger, DHHC-type containing 18 9.2669189E-13 4.07031592E-11 2.4163 0.9061 1.6755 1.6077 0.8285 2.1214 1.2631

27340 UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 4.1479756E-07 2.35891099E-06 2.4157 2.7735 2.4987 1.4646 2.8841 3.8359 1.908263893 UBE2O ubiquitin-conjugating enzyme E2O 7.44955167E-11 1.2975997E-09 2.4152 18.2813 4.3926 1.7427 5.4895 1.3326 1.036779915 ATAD5 ATPase family, AAA domain containing 5 5.84923841E-06 2.58402018E-05 2.4150 0.9409 1.6045 1.6743 0.9592 2.1261 1.540354995 OXSM 3-oxoacyl-ACP synthase, mitochondrial 7.27614757E-05 0.000257405166 2.4139 1.4096 2.2437 4.5050 0.0871 2.9556 1.111923070 CMTR1 cap methyltransferase 1 2.79016202E-09 2.83863254E-08 2.4131 1.8995 3.2840 1.8046 1.8374 3.8739 2.4141

3783 KCNN4 1.25819533E-06 6.41454942E-06 2.4128 0.5559 1.8918 2.1707 0.4969 2.0199 1.7855

57095 PITHD1 2.79795391E-12 9.59178495E-11 2.4122 1.2651 2.0852 2.9070 0.3185 0.8150 2.627711098 PRSS23 protease, serine, 23 0.01625650221 0.032964022678 2.4120 0.3734 1.1349 1.4376 0.5291 0.5992 1.64765160 PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 4.81985636E-10 6.29960052E-09 2.4111 1.1547 0.9186 1.0457 1.0769 1.1109 1.2638833 CARS cysteinyl-tRNA synthetase 9.33705542E-09 8.04369056E-08 2.4107 0.6841 1.0091 0.9492 0.5884 1.2071 1.3268401331 RASA4CP RAS p21 protein activator 4C, pseudogene 1.64373569E-10 2.51333377E-09 2.4105 0.7422 1.6620 1.7919 0.7507 2.6522 1.0590645 BLVRB biliverdin reductase B (flavin reductase (NADPH)) 0.00023879297 0.000756978677 2.4096 0.7294 2.4578 2.2109 0.5208 5.3519 1.305110146 G3BP1 GTPase activating protein (SH3 domain) binding protein 1 1.17670735E-10 1.90281596E-09 2.4091 1.0743 0.6050 1.1539 1.3620 1.0961 1.774554939 COMMD4 COMM domain containing 4 2.83505367E-09 2.87629654E-08 2.4082 1.3579 2.5315 1.9579 0.9178 2.3608 1.9762128312 HIST3H2BB histone cluster 3, H2bb 0.00022669449 0.000721128448 2.4071 2.8696 2.8243 2.2300 1.2967 2.3939 2.103780746 TSEN2 TSEN2 tRNA splicing endonuclease subunit 6.4238851E-06 2.81156849E-05 2.4061 2.5967 1.9425 2.3504 1.4630 1.9390 1.818784541 KBTBD8 kelch repeat and BTB (POZ) domain containing 8 1.54957176E-07 9.80393879E-07 2.4055 1.7725 2.4361 2.1021 1.5495 2.8954 2.344656919 DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33 5.75278506E-09 5.30080124E-08 2.4053 0.9559 1.1901 0.8736 1.0608 2.1248 1.4841125476 INO80C INO80 complex subunit C 6.51988492E-07 3.54135961E-06 2.4049 2.4842 2.0803 2.0781 2.6986 2.0639 1.899265003 MRPL11 mitochondrial ribosomal protein L11 5.7362055E-09 5.29888508E-08 2.4041 1.3861 1.3192 1.1623 1.1914 2.1344 1.69849727 RAB11FIP3 RAB11 family interacting protein 3 (class II) 1.04220816E-08 8.85731515E-08 2.4038 0.5663 0.6704 0.6917 0.4730 0.6661 0.75673611 ILK integrin-linked kinase 5.47356781E-09 5.08481617E-08 2.4033 2.0099 2.2277 1.9823 0.9311 2.4451 1.50414642 MYO1D myosin ID 8.84385475E-06 3.75976999E-05 2.4029 1.9512 2.2027 1.7081 1.3580 2.1011 1.907110865 ARID5A AT rich interactive domain 5A (MRF1-like) 5.47748762E-07 3.02553367E-06 2.4016 1.2641 1.1197 1.3067 1.2891 1.9865 1.767879178 THTPA thiamine triphosphatase 4.9773601E-06 2.23235944E-05 2.4009 0.7526 0.9710 1.1992 0.7541 1.0123 1.427057630 SH3RF1 SH3 domain containing ring finger 1 0.02027055709 0.039903428043 2.4008 0.4081 1.5267 0.6115 0.5476 0.8821 0.81078697 CDC23 cell division cycle 23 2.78642866E-08 2.11787123E-07 2.3995 3.4437 2.0790 1.8770 3.2818 2.6775 2.096023636 NUP62 nucleoporin 62kDa 2.23305403E-09 2.32890202E-08 2.3989 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706175 RPLP0 ribosomal protein, large, P0 7.63255533E-11 1.32191518E-09 2.3982 16.1510 1.0537 8.0154 16.3368 5.1640 3.87107841 MOGS mannosyl-oligosaccharide glucosidase 7.07252398E-12 1.99735948E-10 2.3982 1.6181 1.5869 1.3016 1.3778 1.9526 1.4489162515 SLC16A11 solute carrier family 16, member 11 3.54077423E-05 0.000132820831 2.3973 1.6825 2.0586 1.6663 1.4329 1.5510 1.73498851 CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 7.83783639E-05 0.000275940167 2.3969 1.5542 1.2934 1.5192 1.4642 2.1107 2.532784516 DCTN5 dynactin 5 (p25) 1.07595599E-11 2.75485864E-10 2.3968 0.6893 12.0566 1.9112 0.2889 1.4820 1.017883732 RIOK1 RIO kinase 1 1.03285814E-09 1.204364E-08 2.3964 0.4971 5.5368 0.7516 0.5232 2.2734 0.704411133 KPTN kaptin (actin binding protein) 3.09211073E-05 0.000117169322 2.3953 0.3169 0.3179 0.2983 0.3956 0.3566 0.412254982 CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 9.97145242E-06 4.19135907E-05 2.3950 1.3443 1.4295 1.6798 1.1231 1.6828 1.68677511 XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.01999388E-08 8.68063723E-08 2.3933 0.7547 0.8902 0.8321 0.6231 1.1908 0.8693

6583 SLC22A4 0.00719370099 0.016157751005 2.3930 1.3413 4.1717 1.7124 0.9110 3.6599 1.90826734 SRPR signal recognition particle receptor (docking protein) 1.26789111E-10 2.01757684E-09 2.3914 1.8573 0.2178 2.3026 0.7404 0.1693 1.3240165 AEBP1 AE binding protein 1 7.66002037E-07 4.09433404E-06 2.3899 0.4604 0.9670 0.8224 0.3713 1.1554 0.67944294 MAP3K10 mitogen-activated protein kinase kinase kinase 10 1.96657372E-06 9.61810359E-06 2.3893 1.5289 2.3832 1.9444 1.5628 2.6035 2.705190956 ADCK2 aarF domain containing kinase 2 5.27212408E-09 4.92748088E-08 2.3878 1.3550 0.9200 2.1057 1.1051 1.0765 2.0349285958 SNHG15 chromosome 7 open reading frame 40 1.86126505E-06 9.15451815E-06 2.3873 1.5863 4.1741 2.0350 1.2489 3.8702 2.0902100506714 LOC100506714 uncharacterized LOC100506714 0.00019528262 0.000629423905 2.3872 0.4005 0.7455 2.3465 0.1782 0.2432 1.762026000 TBC1D10B TBC1 domain family, member 10B 1.85521041E-11 4.2855126E-10 2.3867 0.7621 1.5504 0.9064 0.5673 2.2640 1.483029956 CERS2 ceramide synthase 2 9.35621649E-10 1.10795067E-08 2.3859 1.0278 3.3287 1.3648 0.8750 3.4262 2.065484536 C21orf67 chromosome 21 open reading frame 67 0.00425608071 0.010202434755 2.3853 1.1649 8.1916 1.9240 1.0920 1.7615 2.4108677801 SNORA14A small nucleolar RNA, H/ACA box 14A 0.00051796044 0.001525495357 2.3848 0.0907 0.1404 0.2164 0.1373 0.1079 0.1909117246 FTSJ3 FtsJ homolog 3 (E. coli) 1.45006173E-10 2.25302108E-09 2.3846 2.0713 2.5006 2.9380 1.5001 1.2691 1.258580777 CYB5B cytochrome b5 type B (outer mitochondrial membrane) 2.8859128E-11 6.0988763E-10 2.3838 2.4361 1.7586 2.1244 2.2284 2.6497 2.5180489 ATP2A3 ATPase, Ca++ transporting, ubiquitous 2.26455244E-10 3.32085892E-09 2.3837 1.2480 1.0061 0.9336 1.1470 1.0253 1.286184444 DOT1L DOT1-like histone H3K79 methyltransferase 2.51280403E-10 3.6439647E-09 2.3837 1.0941 1.3061 0.7430 0.6768 2.6709 1.16553939 LDHA lactate dehydrogenase A 1.39980829E-06 7.06971328E-06 2.3833 2.0986 2.1843 2.0911 2.1083 3.4081 2.85156832 SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 1.72695649E-07 1.08138962E-06 2.3823 2.6057 2.5690 1.8860 2.3640 5.0251 2.20186904 TBCD tubulin folding cofactor D 7.26549073E-13 3.42152182E-11 2.3822 0.6582 0.8144 0.8932 0.8100 1.2078 1.28268086 AAAS achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A) 3.17190805E-10 4.43436144E-09 2.3805 2.4220 1.3899 2.5186 2.0042 2.2029 2.137290355 C5orf30 chromosome 5 open reading frame 30 9.65113372E-06 4.06761598E-05 2.3799 1.2153 1.8303 1.6469 1.0167 1.6562 2.604165243 ZFP69B ZFP69 zinc finger protein B 0.00010598914 0.000362258421 2.3796 1.4602 2.8639 1.9488 1.2160 2.2622 2.128184331 FAM195A family with sequence similarity 195, member A 7.91769541E-10 9.59364261E-09 2.3792 1.3780 3.0470 1.5197 1.1972 3.6059 1.9281

8693 GALNT4 0.0199017436 0.03927048153 2.3787 1.6131 14.6670 3.0743 1.1364 7.7361 1.726784890 ADO chromosome 10 open reading frame 22 2.12640143E-11 4.78966796E-10 2.3786 1.2819 2.2449 1.7392 1.6455 2.8066 2.726684885 ZDHHC12 zinc finger, DHHC-type containing 12 5.9982612E-10 7.59004353E-09 2.3777 0.2554 0.5205 2.9692 0.1961 0.3798 2.268784464 SLX4 SLX4 structure-specific endonuclease subunit 3.14070899E-07 1.84525812E-06 2.3773 2.3261 4.1342 2.0125 1.8924 6.5060 2.533655611 OTUB1 OTU domain, ubiquitin aldehyde binding 1 1.5350209E-13 1.11301198E-11 2.3768 1.3877 1.9347 2.4074 1.2157 2.1314 2.015154849 DEF8 differentially expressed in FDCP 8 homolog (mouse) 1.68658392E-10 2.56810511E-09 2.3766 0.6072 1.2339 0.7675 0.5044 1.5391 0.473851118 UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) 5.72023046E-09 5.28680076E-08 2.3758 2.5630 1.6628 2.0253 2.2354 3.1343 2.0983

23082 PPRC1 4.95913878E-09 4.68528355E-08 2.3752 0.7936 1.2566 0.8845 0.8836 2.2242 1.37448892 EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 7.31418206E-11 1.28238076E-09 2.3751 1.8641 1.6805 1.9336 1.6782 2.0114 1.99084831 NME2 NME/NM23 nucleoside diphosphate kinase 2 4.66726463E-09 4.45793305E-08 2.3748 1.1398 1.5034 1.7137 1.0242 1.9820 1.79562132 EXT2 exostosin glycosyltransferase 2 2.67994186E-11 5.76092914E-10 2.3747 0.6604 0.7342 0.7375 0.4886 0.6451 0.73361431 CS citrate synthase 1.66511657E-12 6.36506485E-11 2.3745 1.3663 0.8401 1.1778 1.1381 0.9229 1.276557613 KIAA1467 KIAA1467 8.66946791E-06 3.69078559E-05 2.3744 0.8558 1.0621 0.9743 0.7497 1.1128 1.0832

golgi-associated, gamma adaptin ear containing, ARF binding protein 1

solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5

solute carrier family 25 (carnitine/acylcarnitine translocase), member 20

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1

solute carrier family 22 (organic cation/zwitterion transporter), member 4

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)

peroxisome proliferator-activated receptor gamma, coactivator-related 1

5684 PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 5.43796995E-09 5.05846281E-08 2.3740 3.2493 2.1871 1.2776 4.0032 3.4396 1.853084838 ZNF496 zinc finger protein 496 1.956008E-06 9.57492449E-06 2.3734 0.8505 0.6756 1.0717 0.9330 0.8779 1.171456893 UBQLN4 ubiquilin 4 4.31240578E-13 2.39199406E-11 2.3725 2.1658 2.8874 2.6393 1.8948 3.4826 2.664084034 EMILIN2 elastin microfibril interfacer 2 0.00235458208 0.006004595079 2.3724 1.9670 1.6775 1.8618 0.9946 0.7893 1.78531653 DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 2.24147108E-09 2.33634681E-08 2.3721 2.1770 2.2650 1.8379 2.0055 2.9063 2.831825980 AAR2 AAR2 splicing factor homolog (S. cerevisiae) 6.01749432E-13 3.00238811E-11 2.3721 1.9491 3.4086 1.5067 1.7506 4.8841 1.6301

133308 SLC9B2 2.12017802E-07 1.30133614E-06 2.3719 0.5745 0.9220 0.7060 0.6613 0.7737 0.8426645431 FUT8-AS1 FUT8 antisense RNA 1 0.00877037832 0.019265731255 2.3712 3.0597 1.6980 2.8776 5.5561 2.1460 3.380110519 CIB1 calcium and integrin binding 1 (calmyrin) 4.64830332E-12 1.43712011E-10 2.3710 4.1560 4.6211 2.3347 2.6921 6.1006 1.9368122786 FRMD6 FERM domain containing 6 0.00245322006 0.00623438623 2.3710 0.6461 0.3930 0.7641 0.4075 0.4120 0.730410072 DPP3 dipeptidyl-peptidase 3 1.90933436E-06 9.37076483E-06 2.3705 0.9128 1.5436 1.0655 0.7461 2.3023 1.224184627 ZNF469 zinc finger protein 469 0.00062947343 0.0018193196 2.3699 0.0558 0.0713 0.1506 0.2388 0.0139 0.198958509 CACTIN chromosome 19 open reading frame 29 4.13628707E-13 2.33266165E-11 2.3697 1.2307 1.2513 0.9621 0.9733 1.2262 1.0633958 CD40 CD40 molecule, TNF receptor superfamily member 5 0.00077565495 0.002203134977 2.3697 2.0052 1.7915 1.5892 1.4570 2.1337 1.0667255252 LRRC57 leucine rich repeat containing 57 3.98335307E-05 0.000148266098 2.3682 1.1825 0.3309 3.7179 1.4850 0.4351 0.964657572 DOCK6 dedicator of cytokinesis 6 0.00557742797 0.012939406283 2.3682 0.5531 0.2611 0.3230 0.2072 0.2601 0.326010713 USP39 ubiquitin specific peptidase 39 3.26891701E-12 1.08797179E-10 2.3682 0.6108 8.1891 1.4256 0.5758 14.5654 1.412310654 PMVK phosphomevalonate kinase 7.965509E-13 3.64776392E-11 2.3682 1.6526 3.7860 2.1198 1.9173 4.7392 2.64445564 PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 7.14627325E-09 6.36338717E-08 2.3673 1.7150 1.9535 2.1484 1.5109 2.1330 2.59113636 INPPL1 inositol polyphosphate phosphatase-like 1 6.48279654E-13 3.13369467E-11 2.3669 0.8707 1.0082 1.5905 0.7471 0.8623 1.50539128 PRPF4 pre-mRNA processing factor 4 2.61004618E-08 2.0004515E-07 2.3666 9.7705 3.8707 2.9130 3.5396 3.4719 1.214523306 TMEM194A transmembrane protein 194A 7.48506904E-07 4.00959195E-06 2.3663 2.3280 1.9121 1.6265 1.6299 2.6653 2.6161126306 JSRP1 junctional sarcoplasmic reticulum protein 1 0.00471459724 0.011173167423 2.3663 0.3489 0.2731 0.5068 0.4678 0.1178 0.2961162417 NAGS N-acetylglutamate synthase 0.00054114996 0.001586123215 2.3659 1.8611 1.6315 1.8732 1.2375 0.8708 1.9995116461 TSEN15 TSEN15 tRNA splicing endonuclease subunit 2.24409041E-07 1.36498069E-06 2.3657 1.9727 1.7269 1.6139 2.4509 2.3805 1.984511212 PROSC proline synthetase co-transcribed homolog (bacterial) 7.41702046E-11 1.29449798E-09 2.3648 2.3535 1.4889 1.8155 2.0646 2.0512 2.56748879 SGPL1 sphingosine-1-phosphate lyase 1 4.89485131E-05 0.000178770184 2.3638 0.8037 1.7729 1.0568 0.8068 1.5764 1.004554433 GAR1 GAR1 ribonucleoprotein 7.234093E-07 3.89570726E-06 2.3631 2.3320 2.9978 2.1091 2.3975 4.5927 2.2425389813 C9orf172 similar to CG15216-PA 0.01215217465 0.025595911839 2.3627 0.7750 1.0108 1.3730 0.3520 0.4404 0.5473100131551 LINC00887 long intergenic non-protein coding RNA 887 0.01149710421 0.024401799064 2.3623 0.1631 0.1343 0.3355 0.0544 0.2740 0.193655813 UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) 8.36398766E-11 1.42296818E-09 2.3603 0.9526 1.2409 1.0664 0.9299 2.2622 1.2121319085 ITPK1-AS1 ITPK1 antisense RNA 1 0.01075140697 0.023014258227 2.3597 0.3201 0.7238 0.7683 0.1399 0.4234 0.31251849 DUSP7 dual specificity phosphatase 8 6.57626917E-10 8.2077589E-09 2.3596 1.1083 2.2304 1.9687 1.1403 1.7704 3.28589609 RAB36 RAB36, member RAS oncogene family 0.0096135272 0.020887147396 2.3593 1.1515 1.1419 1.1111 0.6898 0.9505 0.72371847 DUSP5 dual specificity phosphatase 6 0.00071751831 0.002050437051 2.3583 2.0651 3.6511 2.2665 1.3664 3.8385 3.151510490 VTI1B vesicle transport through interaction with t-SNAREs 1B 2.28109691E-11 5.04981707E-10 2.3580 1.5757 2.1620 1.8274 1.5627 3.5524 2.40938861 LDB1 LIM domain binding 1 3.32228273E-13 1.98381536E-11 2.3571 2.1487 2.5000 2.3173 1.6856 2.4471 2.6689653333 FAM86B2 family with sequence similarity 86, member B2 0.01057487338 0.022676221843 2.3570 0.4358 0.9479 0.8062 0.3659 1.0173 0.4955222658 KCTD20 potassium channel tetramerisation domain containing 20 6.35381892E-14 5.86348381E-12 2.3565 1.0968 7.2527 0.4871 0.8346 1.6501 0.2306899 CCNF cyclin F 0.00010664298 0.000364220669 2.3565 1.6555 1.8183 2.3275 1.8572 2.3241 3.5293644619 INTS4L2 integrator complex subunit 4-like 2 9.4042725E-05 0.000324829617 2.3549 0.4477 0.5714 1.0927 0.2963 0.5166 0.68048099 CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.00019291771 0.000622240482 2.3531 1.2345 1.8756 1.6090 0.4631 1.0242 1.2062388567 ZNF749 zinc finger protein 749 7.3960853E-05 0.000261294027 2.3525 2.0952 2.6085 2.5508 1.9187 2.7666 3.195655191 NADSYN1 NAD synthetase 1 3.07877401E-07 1.81285221E-06 2.3517 0.9467 1.3496 0.8912 0.8483 1.0549 0.940351776 ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.00037177148 0.00112953252 2.3510 1.5806 1.6125 1.5649 1.3536 1.5997 1.39067186 TRAF2 TNF receptor-associated factor 2 4.5303024E-11 8.68264647E-10 2.3502 1.4271 1.6873 2.0561 0.6583 1.9745 1.307210912 GADD45G growth arrest and DNA-damage-inducible, gamma 0.00481813448 0.011391945292 2.3491 2.7936 2.1618 2.1862 1.6972 1.7061 2.298484617 TUBB6 tubulin, beta 6 class V 0.01645819313 0.033306468597 2.3488 0.7132 1.4698 1.9503 0.5497 1.0967 1.464151529 ANAPC11 anaphase promoting complex subunit 11 6.66173229E-12 1.90788671E-10 2.3483 0.2771 2.8417 1.6193 0.3056 1.6766 1.60878480 RAE1 ribonucleic acid export 1 3.85610067E-10 5.22302976E-09 2.3480 1.3709 1.3830 1.6850 1.6412 2.8801 2.26591147 CHUK conserved helix-loop-helix ubiquitous kinase 1.83806139E-10 2.76647922E-09 2.3476 2.3995 1.4220 2.0682 2.4443 1.5488 2.98905272 SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 1.66257197E-09 1.81798414E-08 2.3469 1.4376 1.8558 1.6085 1.0331 1.8376 1.2176389247 LOC389247 uncharacterized LOC389247 0.01710096062 0.034431818452 2.3448 2.8287 3.7270 1.6224 2.1384 2.3360 2.678810011 SRA1 steroid receptor RNA activator 1 2.94821234E-08 2.22051673E-07 2.3447 1.7652 2.2982 1.4119 1.4151 2.5721 1.193110592 SMC2 structural maintenance of chromosomes 2 2.18359942E-06 1.05552192E-05 2.3446 1.6621 1.7417 1.3403 1.9926 2.9093 1.91071763 DNA2 dynein, axonemal, heavy chain 5 1.5998824E-05 6.43616276E-05 2.3444 2.0077 2.1317 1.3112 1.8951 2.4455 1.4930643866 CBLN3 cerebellin 3 precursor 0.00261006096 0.006589889979 2.3442 0.3321 0.3321 0.3321 0.3970 0.3970 0.397023590 PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 2.97633398E-05 0.000113134126 2.3435 1.3433 0.9217 1.3758 1.2360 1.7142 1.907927175 TUBG2 tubulin, gamma 2 5.72291975E-07 3.14777814E-06 2.3431 0.9402 1.4956 1.4505 0.7510 1.2216 1.3846223 ALDH9A1 aldehyde dehydrogenase 9 family, member A1 7.66558897E-14 6.73392508E-12 2.3424 3.6913 2.4694 6.7725 2.8846 0.8721 4.47871632 ECI1 enoyl-CoA delta isomerase 1 7.65369715E-09 6.73643325E-08 2.3421 0.7363 1.1535 1.2150 0.4667 0.8568 1.5746285590 SH3PXD2B SH3 and PX domains 2B 0.01211440841 0.025531080786 2.3399 1.2260 1.7797 0.8358 0.9663 1.3546 0.642110201 NME6 NME/NM23 nucleoside diphosphate kinase 6 8.06022919E-08 5.47903674E-07 2.3394 2.7352 4.3814 2.0518 2.9592 5.1422 3.05343795 KHK ketohexokinase (fructokinase) 8.79497574E-05 0.000306040367 2.3352 1.3869 2.9447 1.8747 1.1121 3.6515 2.46243553 IL1B interleukin 1, beta 0.01931962338 0.038307993307 2.3346 0.2206 0.2093 0.2602 0.2509 0.2207 0.282085476 GFM1 G elongation factor, mitochondrial 1 3.80523089E-10 5.17030258E-09 2.3339 1.2966 2.6733 1.0052 1.5254 3.6370 1.153685465 EPT1 ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) 1.86545809E-06 9.1726723E-06 2.3320 0.3321 0.3321 0.3321 0.3970 0.3970 0.397022845 DOLK dolichol kinase 2.1068606E-07 1.29433479E-06 2.3317 2.0363 0.5382 2.0479 1.2023 0.1243 0.4637

10509 SEMA4B 6.81787097E-06 2.96680491E-05 2.3314 0.8158 1.6483 1.2889 0.7039 1.6077 1.2294677802 SNORA14B small nucleolar RNA, H/ACA box 14B 9.31824031E-05 0.000322040641 2.3312 2.6457 3.7479 2.1725 1.4779 4.0321 1.613079760 GEMIN7 gem (nuclear organelle) associated protein 7 5.83811517E-08 4.0934014E-07 2.3309 2.4324 1.8060 2.0948 1.6350 2.0781 1.696564320 RNF25 ring finger protein 25 2.83470055E-09 2.87629654E-08 2.3298 0.0796 0.4804 2.0504 0.7650 0.2587 1.880484315 MON1A MON1 secretory trafficking family member A 1.41590802E-08 1.16695857E-07 2.3296 1.5708 1.6598 2.1157 0.7311 1.6880 1.992955222 LRRC20 leucine rich repeat containing 20 7.64579542E-06 3.29578373E-05 2.3289 0.7008 0.8240 0.7247 0.7549 0.6109 0.829963943 FKBPL FK506 binding protein like 0.00011259711 0.000382696137 2.3285 0.8205 1.0402 1.1209 0.7926 1.2486 1.23281874 E2F4 E4F transcription factor 1 6.97638206E-12 1.9763171E-10 2.3272 2.4972 2.3517 2.1127 2.1655 2.5602 1.81128153 RND2 Rho family GTPase 2 0.00990881082 0.02145695559 2.3270 1.8199 2.4170 1.5478 1.2439 2.0848 1.578855017 C14orf119 chromosome 14 open reading frame 119 8.45122379E-10 1.01592606E-08 2.3261 3.2960 8.5572 5.1944 2.7345 16.2771 7.645525920 NELFB negative elongation factor complex member B 2.57919525E-13 1.63126369E-11 2.3256 1.3584 7.1912 1.3807 1.4067 6.6523 2.144155605 KIF21A kinesin family member 21A 4.13731641E-06 1.88333446E-05 2.3254 0.3926 0.7146 0.4140 0.4459 0.8352 0.43275917 RARS arginyl-tRNA synthetase 1.73547156E-09 1.88503274E-08 2.3252 1.7229 1.5963 1.3144 1.8186 2.8013 1.5612129138 ANKRD54 ankyrin repeat domain 54 7.73428979E-07 4.12736399E-06 2.3246 0.2525 0.9462 1.1438 0.1980 0.4306 2.992984319 CMSS1 chromosome 3 open reading frame 26 1.03281669E-06 5.3658307E-06 2.3233 1.5200 1.4035 1.2028 1.4800 1.3543 1.37903619 INCENP inner centromere protein antigens 135/155kDa 4.79354672E-07 2.68344625E-06 2.3229 1.2087 2.2842 1.4437 0.8140 1.8120 2.232780301 PLEKHO2 pleckstrin homology domain containing, family O member 2 2.28947166E-08 1.78531423E-07 2.3213 2.0810 2.0860 2.1985 1.6256 2.8765 2.60726305 SBF1 SET binding factor 1 4.57152144E-12 1.4230126E-10 2.3197 0.3675 0.5476 0.6163 0.4261 0.8882 0.748754039 PCBP3 poly(rC) binding protein 3 0.00103596779 0.002867192289 2.3196 0.3847 0.5567 0.5703 0.4064 0.5427 0.489610844 TUBGCP2 tubulin, gamma complex associated protein 2 1.95000694E-13 1.3245549E-11 2.3193 0.1541 0.1880 0.2853 0.3497 0.1932 0.34119880 ZBTB39 zinc finger and BTB domain containing 39 2.67025164E-10 3.85660468E-09 2.3185 2.4960 1.0538 1.6763 1.6362 1.4136 1.353085235 HIST1H2AH histone cluster 1, H2ah 1.46759607E-05 5.94587925E-05 2.3184 0.3321 0.3321 0.3321 0.3970 0.3970 0.39703749 KCNC4 potassium voltage-gated channel, Shaw-related subfamily, member 4 1.22336803E-05 5.04249508E-05 2.3176 1.0345 2.5525 2.0933 0.8718 2.5282 2.828111113 CIT citron (rho-interacting, serine/threonine kinase 21) 0.00014439897 0.000479371011 2.3170 0.7897 0.5611 1.1132 0.5578 0.6517 0.98953156 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.6740375E-08 2.0417891E-07 2.3165 0.6827 1.0202 0.7326 0.8139 1.1589 0.7523874 CBR3 carbonyl reductase 3 2.91717956E-06 1.372013E-05 2.3153 1.3787 2.4696 1.5929 1.3163 1.9759 2.1623115 ADCY9 adenylate cyclase 9 1.1967984E-05 4.94413301E-05 2.3152 0.9786 1.6842 2.2836 0.8339 1.4103 2.55331371 CPOX coproporphyrinogen oxidase 2.47565849E-14 3.14890479E-12 2.3143 1.6322 4.3106 1.8959 1.5308 4.5520 2.69348625 RFXANK regulatory factor X-associated ankyrin-containing protein 6.28653485E-13 3.06313506E-11 2.3142 1.3550 1.8633 1.2444 1.0304 1.9817 0.868184939 MUM1 melanoma associated antigen (mutated) 1 2.98119243E-08 2.2407383E-07 2.3136 0.3509 0.4733 0.5360 0.3017 0.4812 0.54872833 CXCR3 chemokine (C-X-C motif) receptor 3 0.00054029178 0.001583861933 2.3135 1.2209 1.2847 2.7312 0.6021 0.9777 1.66577846 TUBA1A tubulin, alpha 1a 8.43051766E-06 3.59660095E-05 2.3133 0.8219 1.5138 1.2408 1.1100 1.8899 1.65946341 SCO1 SCO1 cytochrome c oxidase assembly protein 7.70168408E-11 1.32988323E-09 2.3132 0.9197 11.9351 1.7679 0.2642 22.1656 1.5833116444 GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 0.00624976572 0.014295908772 2.3121 0.1840 0.8674 0.7310 0.1325 0.5134 0.517923149 FCHO1 FCH domain only 1 6.55717963E-11 1.17119048E-09 2.3115 1.0273 1.2825 1.2749 0.8407 1.3606 1.320690850 ZNF598 zinc finger protein 598 1.51939033E-12 6.02776456E-11 2.3112 1.1052 1.0508 1.3297 0.8273 1.6375 1.33942118 ETV4 ets variant 4 0.01469576838 0.030201448641 2.3106 0.9532 1.2235 0.8284 0.5972 0.8960 0.6862140465 MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 2.52039852E-07 1.51389618E-06 2.3103 2.1625 2.2196 2.3807 1.9530 1.6877 2.069357661 PHRF1 PHD and ring finger domains 1 1.93843212E-11 4.44962709E-10 2.3098 0.9644 0.8349 1.0700 1.4691 1.7026 1.2839503542 SPRN shadow of prion protein homolog (zebrafish) 0.00027582523 0.000863584415 2.3085 0.5297 0.7886 0.4361 0.2651 1.1973 0.36815518 PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 5.63657699E-13 2.93423176E-11 2.3076 1.0037 1.3371 1.2777 0.9559 1.9320 1.4781976 CD97 CD97 molecule 5.57794323E-10 7.13227283E-09 2.3069 1.8142 2.7962 2.1368 1.9742 3.9937 2.653454853 WDR55 WD repeat domain 55 2.96533815E-11 6.22074153E-10 2.3053 1.7803 1.3651 1.5790 1.9784 1.6922 1.872056957 OTUD7B OTU domain containing 7B 1.89647813E-07 1.17785344E-06 2.3050 0.8892 1.5221 0.9425 0.7773 1.3704 1.096554020 SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 6.89204757E-12 1.96154974E-10 2.3047 0.8580 1.8165 0.8814 0.7249 1.9142 1.2064445577 C9orf129 chromosome 9 open reading frame 129 1.79410945E-05 7.14515428E-05 2.3044 1.0547 0.7699 0.6192 0.6815 0.7109 0.472351203 NUSAP1 nucleolar and spindle associated protein 1 2.28718938E-05 8.90317946E-05 2.3042 0.6577 19.2965 0.5793 0.4490 6.0706 1.0315677819 SNORA37 small nucleolar RNA, H/ACA box 37 6.59179455E-05 0.000235061027 2.3034 1.2090 1.6318 1.4841 0.9450 1.2434 0.636455536 CDCA7L cell division cycle associated 7-like 8.87784668E-07 4.67372253E-06 2.3024 4.0236 4.0535 1.7546 3.6150 4.4624 1.72222542 SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 1.15815741E-08 9.72958719E-08 2.3018 1.0798 1.3408 1.4824 0.8523 1.3103 1.24667855 FZD5 frizzled class receptor 5 0.01935829886 0.038359704678 2.3018 1.6171 1.8908 2.3786 0.9410 1.2599 2.1769400931 MIRLET7BHG MIRLET7B host gene (non-protein coding) 0.00460799067 0.01094892139 2.3016 0.1948 0.2303 0.2005 0.2345 0.2510 0.292327158 NDOR1 NADPH dependent diflavin oxidoreductase 1 1.1859325E-09 1.36028617E-08 2.2992 0.6214 2.6756 2.2705 0.2795 1.9525 0.3694924 CD7 CD7 molecule 3.23320918E-07 1.89410703E-06 2.2988 1.6011 2.5777 1.8616 1.5398 3.5247 3.1101116983 ACAP3 centaurin, beta 5 2.06519403E-07 1.27140247E-06 2.2987 0.5678 0.8615 0.9654 0.4861 0.5121 0.640180895 ILKAP integrin-linked kinase-associated serine/threonine phosphatase 6.42837784E-09 5.83503824E-08 2.2983 1.8930 2.3039 2.1865 1.4295 3.5884 2.078290550 MCU mitochondrial calcium uniporter 5.62380467E-05 0.000203159666 2.2975 2.8190 1.3223 1.5760 2.1560 1.0541 1.480191433 RCCD1 RCC1 domain containing 1 3.14768641E-05 0.000119077694 2.2962 0.9131 1.0172 1.6773 0.8298 1.0455 1.924051102 MECR mitochondrial trans-2-enoyl-CoA reductase 1.37181964E-05 5.5975633E-05 2.2941 1.4500 2.5865 1.6158 1.0107 2.2399 1.46362316 FLNA filamin A, alpha 1.43552788E-09 1.59549669E-08 2.2935 0.7032 0.4605 1.1087 0.6091 0.2313 0.92541337 COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 5.11110681E-10 6.62341444E-09 2.2931 1.9746 2.4529 1.9592 1.8321 1.7627 2.13204520 MTF1 metal-regulatory transcription factor 1 3.970013E-09 3.86262394E-08 2.2923 2.0309 1.4774 1.7399 1.5997 2.2529 2.10714478 MSN moesin 7.97159782E-15 1.51707465E-12 2.2918 2.1812 1.6621 1.3167 1.8025 1.6496 1.34289696 CROCC ciliary rootlet coiled-coil, rootletin 7.85092221E-09 6.89341906E-08 2.2918 0.5311 0.7136 0.6832 0.4455 0.5350 0.633357592 ZNF687 zinc finger protein 687 6.00135168E-13 3.00238811E-11 2.2913 0.7577 1.5829 1.0866 0.9085 2.0607 2.065755157 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 1.42913824E-06 7.2036452E-06 2.2910 12.1074 3.6229 0.9199 1.4703 28.1197 0.798491368 CDKN2AIPNL similar to RIKEN cDNA A430101B06 gene 1.39289871E-07 8.91158388E-07 2.2908 3.4230 3.5534 2.0852 2.3416 2.3389 2.323110440 TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 2.0227251E-08 1.60065973E-07 2.2889 1.3994 1.3723 1.6641 2.2511 2.8241 2.64545422 POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 7.55061886E-06 3.26081087E-05 2.2882 1.4076 2.4197 2.2032 1.1903 1.8521 2.687454892 NCAPG2 non-SMC condensin II complex, subunit G2 0.00018741947 0.00060600398 2.2875 0.4170 0.4809 0.6927 0.4619 0.5288 0.83369961 MVP major vault protein 4.05493118E-09 3.93653912E-08 2.2874 1.3940 1.7389 1.3638 1.3571 1.6196 1.496955968 NSFL1C NSFL1 (p97) cofactor (p47) 2.64268289E-11 5.70095652E-10 2.2868 1.1556 0.8803 1.0279 1.0679 0.6157 0.9852

57553 MICAL3 3.11044407E-07 1.82863687E-06 2.2862 0.4189 0.7567 0.6116 0.2875 0.7489 0.6218

solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

microtubule associated monooxygenase, calponin and LIM domain containing 3

81490 PTDSS2 phosphatidylserine synthase 2 6.27882253E-09 5.7158606E-08 2.2861 1.0264 2.2470 1.9444 0.7639 2.6223 2.1322147912 SIX5 SIX homeobox 5 0.00061022849 0.001768452817 2.2855 2.1473 3.6197 1.8583 1.2835 2.6370 2.603079944 L2HGDH L-2-hydroxyglutarate dehydrogenase 3.19085708E-07 1.87229739E-06 2.2825 0.9485 1.1398 0.7170 0.3959 0.6440 0.71718815 BANF1 barrier to autointegration factor 1 6.88158168E-11 1.2219656E-09 2.2815 1.0282 0.8228 1.1555 0.7376 0.3701 0.4737100131897 FAM196B family with sequence similarity 196, member B 0.00174280028 0.004579957807 2.2804 0.1013 0.0245 0.1365 0.0575 0.0333 0.1545

55627 SMPD4 1.25911776E-09 1.43701435E-08 2.2793 0.3781 0.6388 1.2858 0.1951 0.6448 1.0442653857 ACTR3C actin-related Arp11 0.00016676244 0.000545192936 2.2788 0.5901 0.8171 1.2734 0.3201 0.4632 0.583779671 NLRX1 NLR family member X1 1.2448566E-09 1.42162623E-08 2.2786 0.9054 1.9226 1.6527 0.7361 3.1412 2.054510025 MED16 mediator complex subunit 16 1.65784565E-12 6.35055675E-11 2.2782 0.4986 0.5813 0.5976 0.3845 0.4944 0.54228795 TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.34675171E-08 1.11499081E-07 2.2779 0.8769 0.4331 1.3325 0.8847 0.2936 1.1649642826 BMS1P6 Hypothetical protein LOC642826 0.00721291419 0.016194933402 2.2778 1.1700 0.9208 1.5816 1.2437 0.3725 0.579628991 COMMD5 COMM domain containing 5 1.96732118E-11 4.49898531E-10 2.2777 0.9674 0.8739 0.9715 0.9299 0.9947 1.4226

347734 SLC35B2 5.27205648E-09 4.92748088E-08 2.2774 1.4271 1.6801 1.6601 1.2782 2.3500 1.834510989 IMMT inner membrane protein, mitochondrial 4.15656574E-12 1.32777568E-10 2.2772 1.0986 0.9670 1.0905 0.9317 1.2157 1.379110056 FARSB phenylalanyl-tRNA synthetase, beta subunit 4.4448556E-08 3.21904089E-07 2.2765 2.1297 2.9948 2.0579 1.8148 4.8542 2.504784274 COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) 1.68299306E-07 1.05821229E-06 2.2751 3.0816 3.1988 2.1801 3.6237 4.2767 2.2994

90480 GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 7.06235068E-09 6.29786586E-08 2.2745 1.6227 2.5158 1.9945 2.0973 2.8252 2.49646242 RTKN rhotekin 0.00321749176 0.007941376404 2.2743 0.7247 1.1121 1.7195 0.5013 1.0163 1.096891300 R3HDM4 R3H domain containing 4 3.4200824E-10 4.73063934E-09 2.2738 0.7699 2.3229 1.4361 0.7495 4.0509 1.632611222 MRPL3 mitochondrial ribosomal protein L3 6.7644994E-08 4.68185352E-07 2.2737 2.5733 3.8595 2.2049 2.1835 4.9465 2.70122117 ETV3 ets variant 3 1.6432277E-06 8.18344415E-06 2.2732 2.2056 2.4559 2.5831 1.9019 1.8391 2.7214126298 IRGQ immunity-related GTPase family, Q 4.45005592E-08 3.22025433E-07 2.2720 1.4850 1.9944 1.7381 1.1881 2.3740 2.57918310 ACOX3 acyl-CoA oxidase 3, pristanoyl 5.74317664E-07 3.15796941E-06 2.2709 1.1587 1.5510 1.0282 1.0002 1.6951 0.98141665 DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 4.42540363E-10 5.85524802E-09 2.2704 0.6583 0.5536 0.5686 0.8307 0.8146 0.9801283248 RCOR2 REST corepressor 2 0.02535125682 0.048428454222 2.2700 1.3131 2.1386 1.5981 0.7401 1.9489 1.631551107 APH1A APH1A gamma secretase subunit 4.95530958E-09 4.68528355E-08 2.2700 2.2949 1.1743 1.9741 1.5841 1.6189 2.23595327 PLAT plasminogen activator, tissue 0.00516140149 0.012100221702 2.2693 0.0458 0.0818 0.3650 0.1499 0.0618 0.30715707 PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 1.96721328E-09 2.09103671E-08 2.2693 1.6386 2.9266 1.7136 1.3298 3.6903 2.353457617 VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 3.11714498E-08 2.3323699E-07 2.2684 1.3198 3.1944 1.6855 1.1663 3.1508 1.33909308 CD83 CD83 molecule 0.00012268849 0.000413685951 2.2679 1.3152 2.0788 1.5254 0.9811 2.3488 1.628292558 CCDC64 coiled-coil domain containing 64 8.31070354E-06 3.55295215E-05 2.2679 0.8826 0.9167 0.8465 0.9156 1.8435 1.18213398 ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.00135145237 0.003646985336 2.2674 2.9319 2.2275 2.3430 3.1558 3.3549 3.38209249 DHRS3 dehydrogenase/reductase (SDR family) member 3 2.96715234E-06 1.39300636E-05 2.2673 1.3385 3.2400 1.4905 1.2535 2.9172 1.989057017 COQ9 coenzyme Q9 homolog (S. cerevisiae) 5.98859723E-10 7.58832514E-09 2.2666 1.3530 1.7893 0.5749 0.9110 0.1492 0.181880174 DBF4B DBF4 homolog B (S. cerevisiae) 0.00083166687 0.002349935567 2.2664 1.8963 1.5743 1.8969 1.7621 1.9282 1.9061100129518 LOC100129518 uncharacterized LOC100129518 0.01804648462 0.036100872238 2.2649 0.3321 0.3321 0.3321 0.3970 0.3970 0.397064794 DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 3.10783478E-09 3.11158121E-08 2.2648 4.6808 1.0596 3.6105 1.1422 0.5866 6.159355336 FBXL8 Q96CD0,F-box and leucine-rich repeat protein 8 0.00066107789 0.001900741968 2.2648 0.2260 1.1870 2.9118 0.3785 2.1018 0.508423237 ARC activity-regulated cytoskeleton-associated protein 0.01435759451 0.029603020421 2.2642 0.9352 1.8958 0.8174 0.5281 0.9945 0.56199730 VPRBP Vpr (HIV-1) binding protein 1.17532093E-10 1.90281596E-09 2.2633 1.0577 0.9324 0.8250 1.0238 1.1303 1.02723608 ILF2 interleukin enhancer binding factor 2 1.66693648E-08 1.34532966E-07 2.2630 3.0626 5.7019 2.0498 3.5727 9.4964 2.9078283922 LOC283922 hypothetical protein LOC283922 4.04876546E-06 1.8448639E-05 2.2586 2.2374 2.4117 1.8561 1.8048 2.9249 2.18916871 TADA2A transcriptional adaptor 2A 5.34905063E-06 2.3850135E-05 2.2583 0.3667 2.5138 1.5167 0.5191 0.6633 0.5357921 CD5 CD5 molecule 1.9491444E-09 2.07545259E-08 2.2574 1.7181 2.8207 2.3697 2.3124 3.7119 2.6879

27090 ST6GALNAC4 4.76150142E-09 4.52898114E-08 2.2573 1.4049 3.1087 2.3373 1.0965 4.0094 2.41631855 DVL1 dishevelled segment polarity protein 3 6.14102491E-09 5.61324698E-08 2.2567 0.6915 1.6992 0.8508 0.5811 1.6010 1.186727229 TUBGCP4 tubulin, gamma complex associated protein 4 8.52751675E-09 7.39159327E-08 2.2566 1.5094 1.5125 1.1358 1.1815 1.8832 1.470554461 FBXW5 F-box and WD repeat domain containing 5 1.64696071E-12 6.32211472E-11 2.2566 0.8996 2.1925 1.7232 0.9108 2.3393 2.518723420 NOMO1 NODAL modulator 1 9.16447097E-10 1.08877252E-08 2.2553 1.2058 1.9827 1.5112 1.1376 2.8153 1.710851232 CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.00240277133 0.006115536659 2.2541 1.6016 5.3762 2.1124 0.9027 2.7847 2.183492703 TMEM183A transmembrane protein 183A 1.10956907E-12 4.66070025E-11 2.2523 12.8406 1.8606 0.7556 8.7008 1.1519 0.358965220 NADK NAD kinase 3.04783115E-09 3.06831795E-08 2.2520 0.4445 0.9171 0.7242 0.3199 0.8040 0.572126519 TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 4.38118142E-08 3.18175465E-07 2.2514 2.2418 2.4852 2.2278 1.8667 2.4087 2.6625100507178 SLFNL1-AS1 SLFNL1 antisense RNA 1 0.00010647561 0.000363717025 2.2508 0.2735 0.1731 0.1354 0.3035 0.0755 0.2227

7520 XRCC5 9.71920811E-10 1.14131986E-08 2.2499 1.5801 1.8686 1.4340 1.4937 1.8580 1.28307216 TRO trophinin 0.00544090872 0.01265965672 2.2497 0.8435 1.1083 1.2557 0.9429 0.9203 0.995154436 SH3TC1 SH3 domain and tetratricopeptide repeats 1 1.68192215E-05 6.73949158E-05 2.2496 1.6992 1.4609 1.7487 1.1905 1.1812 1.25993832 KIF11 kinesin family member 11 0.00015201872 0.000501387371 2.2479 2.2706 2.7694 2.9471 1.9251 2.7558 4.65199094 UNC119 unc-119 homolog (C. elegans) 1.57018071E-11 3.73086372E-10 2.2474 1.0766 1.9870 1.3391 0.5803 1.8988 1.22333705 ITPK1 inositol-tetrakisphosphate 1-kinase 3.47613982E-11 7.02610917E-10 2.2470 1.7774 1.8842 1.8921 1.1989 1.5830 2.327391694 LONRF1 LON peptidase N-terminal domain and ring finger 1 0.00038633534 0.001170278411 2.2457 0.4826 0.7110 0.4743 0.5016 0.5553 0.837010548 TM9SF1 transmembrane 9 superfamily member 1 1.97908038E-07 1.22292042E-06 2.2454 0.9350 1.8006 1.1485 0.8334 1.8624 1.283951428 DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.44537338E-09 2.5229736E-08 2.2453 1.7026 2.5554 1.6284 1.7583 3.4260 2.387892935 MARS2 methionyl-tRNA synthetase 2, mitochondrial 8.73085224E-07 4.60670321E-06 2.2452 2.0132 2.6545 1.9126 2.6608 4.3885 2.70602146 EZH2 enhancer of zeste homolog 2 (Drosophila) 1.04873769E-07 6.90293049E-07 2.2434 1.4600 1.3273 0.8530 1.1644 1.7132 1.250584942 WDR73 WD repeat domain 73 6.12247583E-07 3.3524087E-06 2.2422 1.6947 3.2501 1.4887 1.7443 4.1779 1.7178

23207 PLEKHM2 1.08184866E-12 4.58643588E-11 2.2405 1.9871 2.9266 1.7968 1.4693 3.7656 2.534379446 WDR25 WD repeat domain 25 1.34642748E-05 5.5037859E-05 2.2403 2.4267 1.6873 0.8179 2.0347 0.4402 0.307059274 MESDC1 mesoderm development candidate 1 3.20558951E-11 6.59600581E-10 2.2401 2.3008 3.5299 1.8406 1.9424 3.7255 2.26271613 DAPK3 death-associated protein kinase 3 4.8043568E-10 6.28833865E-09 2.2398 0.9137 0.8632 0.6890 0.6152 0.7962 0.730451056 LAP3 leucine aminopeptidase 3 0.0001109569 0.000377542747 2.2398 2.0214 2.1579 1.6640 2.1671 2.5358 2.300379004 CUEDC2 CUE domain containing 2 1.25455889E-12 5.12825503E-11 2.2390 1.0409 1.2633 1.4483 0.8386 1.2089 1.089355245 UQCC ubiquinol-cytochrome c reductase complex assembly factor 1 8.34876057E-09 7.2736251E-08 2.2389 0.7023 1.0411 1.1988 0.6495 0.9034 0.8877283212 KLHL35 hypothetical protein FLJ33790 0.00175407237 0.004605605731 2.2379 0.6229 0.8331 1.3957 0.3647 0.3782 0.97814927 NUP88 nucleoporin 88kDa 5.4054438E-09 5.03406061E-08 2.2374 14.6802 3.7082 7.2522 5.6665 7.1752 6.7062115106 HAUS1 HAUS augmin-like complex, subunit 1 3.06126515E-07 1.80320557E-06 2.2366 2.8177 13.3911 1.9773 1.2794 4.6725 0.894851593 SRRT serrate RNA effector molecule homolog (Arabidopsis) 1.94469534E-07 1.20411634E-06 2.2364 1.6861 1.7228 1.8451 1.7414 1.8971 2.8101113277 TMEM106A transmembrane protein 106A 0.00042614822 0.001276488582 2.2362 1.7869 2.0528 2.8068 1.7156 1.8980 2.5293284353 NKPD1 NTPase, KAP family P-loop domain containing 1 0.00149129312 0.003987256066 2.2345 0.0557 0.1647 0.0595 0.1868 0.0314 0.10334668 NAGA N-acetylgalactosaminidase, alpha- 5.25907993E-06 2.34776224E-05 2.2328 1.7153 2.1667 2.0205 1.1245 1.8689 2.02394116 MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 1.38878871E-08 1.14771358E-07 2.2327 0.2996 0.2943 1.4756 0.3970 0.3970 0.39707760 ZNF213 zinc finger protein 213 3.74385413E-06 1.72311593E-05 2.2327 1.5054 1.1398 0.9758 1.2680 1.8521 1.38124082 MARCKS myristoylated alanine-rich protein kinase C substrate 0.01044555673 0.022448978184 2.2327 2.1580 1.8557 2.7209 1.6291 1.6749 2.1380125061 AFMID arylformamidase 0.00014156146 0.000470977953 2.2324 0.1895 6.5669 2.1736 0.0478 0.9639 1.6528955 ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 4.12387707E-12 1.31964066E-10 2.2306 0.6712 0.9203 0.8788 0.7798 1.0655 0.99679019 MPZL1 myelin protein zero-like 1 3.12236833E-06 1.45950151E-05 2.2305 0.9738 2.0026 0.9214 0.7436 1.4467 1.070010489 LRRC41 leucine rich repeat containing 41 8.37956765E-13 3.79929181E-11 2.2301 1.0726 3.1210 1.5001 0.8506 5.5305 3.24335662 PSD pleckstrin and Sec7 domain containing 3.08761217E-05 0.000117023127 2.2299 0.6841 1.9340 1.1259 0.3963 1.7139 0.85002002 ELK1 ELK1, member of ETS oncogene family 2.27690408E-08 1.77793126E-07 2.2291 1.9696 1.8123 2.1365 1.4510 2.3413 2.94287625 ZNF74 zinc finger protein 74 1.01946529E-06 5.30098741E-06 2.2289 1.9278 1.6738 1.7119 2.0322 1.7036 1.7487100293516 ZNF587B zinc finger protein 587B 9.87848318E-05 0.000339988029 2.2280 0.3321 0.3321 0.3321 0.3970 0.3970 0.397081572 PDRG1 p53 and DNA-damage regulated 1 5.63727633E-09 5.22334245E-08 2.2275 0.9462 1.3324 1.3071 0.9548 2.3080 1.718984364 ARFGAP2 zinc finger protein 289, ID1 regulated 1.43088206E-09 1.59313047E-08 2.2269 0.8221 0.6491 1.2151 0.9918 1.2147 1.3421200933 FBXO45 F-box protein 45 8.26293052E-09 7.21013689E-08 2.2269 7.0378 3.0301 2.7736 6.9348 0.9588 1.290154802 TRIT1 tRNA isopentenyltransferase 1 4.95590771E-05 0.000180855494 2.2265 1.6128 1.4410 1.3456 1.6654 1.9050 1.310484264 HAGHL hydroxyacylglutathione hydrolase-like 5.36545893E-05 0.000194712345 2.2258 2.2475 2.4447 1.0737 1.7005 1.3286 2.22508241 RBM10 RNA binding motif protein 10 4.86755115E-11 9.20702842E-10 2.2252 1.0571 1.6612 0.5781 0.4682 3.0613 0.32016753 SSTR3 somatostatin receptor 3 0.00674034523 0.015284138501 2.2251 0.2678 0.2763 0.4183 0.2794 0.3293 0.275079794 C12orf49 chromosome 12 open reading frame 49 2.25499926E-12 8.04752861E-11 2.2247 0.6775 2.7870 1.4474 0.5767 5.8368 0.629451010 EXOSC3 exosome component 3 8.03259635E-09 7.02929121E-08 2.2234 1.6794 1.7155 1.7096 1.7067 2.6121 2.7346414332 LCN10 lipocalin 10 0.01859273961 0.037055686979 2.2233 0.3780 0.4645 0.4997 0.3306 0.3629 0.4060

100288842 LOC100288842 0.00158008494 0.004198242253 2.2230 3.1867 0.3683 0.8703 3.9507 2.8091 0.778957678 GPAM glycerol-3-phosphate acyltransferase, mitochondrial 9.94199509E-05 0.000341851965 2.2220 1.7535 2.5710 1.8416 1.4863 2.5206 1.894655798 METTL2B methyltransferase like 2B 5.12257459E-08 3.64484747E-07 2.2217 1.7415 1.7863 1.7973 1.6391 2.0536 2.056479081 C11orf48 chromosome 11 open reading frame 48 2.32214163E-12 8.22290154E-11 2.2207 0.4833 5.1353 5.1980 0.0512 0.7153 4.4163254122 SNX32 hypothetical protein FLJ30934 0.00051931708 0.001528998007 2.2199 1.5680 2.2925 2.8386 1.1898 2.1570 2.364651287 COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) 4.51680391E-08 3.26467725E-07 2.2191 0.3321 0.3321 0.3321 0.3970 0.3970 0.397010946 SF3A3 splicing factor 3a, subunit 3, 60kDa 3.5603855E-12 1.17428455E-10 2.2191 1.9030 2.9816 1.8274 1.9285 4.9636 2.564979654 HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 3.6416016E-12 1.19406428E-10 2.2182 0.6579 1.0880 0.5887 0.6522 1.2598 0.915154973 CPSF3L cleavage and polyadenylation specific factor 3-like 5.54553598E-11 1.02558738E-09 2.2178 5.2186 0.1964 0.8379 0.6241 0.4445 0.66621434 CSE1L CSE1 chromosome segregation 1-like (yeast) 1.93720655E-07 1.20002974E-06 2.2173 1.0668 1.0448 0.7911 1.0452 1.6328 1.322964410 KLHL25 kelch-like family member 25 3.93634876E-06 1.80037458E-05 2.2168 2.0170 1.0744 1.8427 1.7331 1.0682 2.6767284358 MAMSTR likely ortholog of MEF2-activating SAP transcriptional regulator 0.00502502374 0.011827545251 2.2156 0.3035 0.3095 0.6237 0.1853 0.1837 0.40157027 TFDP1 transcription factor Dp-1 1.22506247E-06 6.26310615E-06 2.2155 1.7411 1.3178 2.0995 1.1301 2.0081 1.636480271 ITPKC inositol-trisphosphate 3-kinase C 2.8610208E-08 2.16608603E-07 2.2154 2.3563 4.7872 2.0886 1.9781 3.7441 1.695110220 GDF11 growth differentiation factor 11 1.29058791E-08 1.07140492E-07 2.2153 1.2580 1.3420 1.3484 0.9832 1.0769 1.2954

11226 GALNT6 7.67169205E-06 3.30528548E-05 2.2148 0.3985 0.3880 0.4787 0.3302 0.1855 0.3048201164 PLD6 similar to CG12314 gene product 1.67035221E-07 1.05098745E-06 2.2144 0.7788 0.9141 0.8656 0.5848 1.7048 0.905010360 NPM3 nucleophosmin/nucleoplasmin 3 4.45442453E-07 2.51595811E-06 2.2129 1.4051 1.8708 1.7948 0.8832 2.0996 1.856751067 YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 2.64420826E-08 2.02239319E-07 2.2129 1.9572 1.6777 1.3635 2.1645 2.7763 2.509756006 SMG9 SMG9 nonsense mediated mRNA decay factor 1.67783997E-10 2.55692176E-09 2.2100 1.5160 2.4448 1.8856 1.4667 2.7942 2.68925551 PRF1 perforin 1 (pore forming protein) 0.00012479647 0.000420250857 2.2091 1.7825 1.1112 1.7411 1.2535 0.9006 1.478755527 FEM1A fem-1 homolog a (C. elegans) 3.64000645E-10 4.98951222E-09 2.2074 1.1996 1.8829 1.4697 0.8925 2.7999 2.421683862 TMEM120A transmembrane protein 120A 4.76190921E-07 2.67228517E-06 2.2064 0.5167 1.7593 1.0010 0.6143 2.0074 1.169654936 ADPRHL2 ADP-ribosylhydrolase like 2 2.3909476E-07 1.44564509E-06 2.2062 1.9851 1.9322 2.2658 2.4214 2.5992 2.29317458 EIF4H eukaryotic translation initiation factor 4H 7.36140044E-12 2.0629986E-10 2.2059 2.1718 3.5061 1.9464 2.2871 4.3852 2.48487468 WHSC1 Wolf-Hirschhorn syndrome candidate 1 7.73725689E-10 9.41246057E-09 2.2054 0.2624 0.6659 0.5986 0.2308 0.9672 1.148855006 TRMT61B tRNA methyltransferase 61 homolog B (S. cerevisiae) 8.13878758E-05 0.000285654873 2.2041 1.6169 2.4125 1.7033 1.6969 4.8185 2.772754929 TMEM161A transmembrane protein 161A 1.37463236E-09 1.54377889E-08 2.2041 1.7555 1.1673 1.6133 1.2674 1.2878 1.286383871 RAB34 RAB34, member RAS oncogene family 9.33737859E-06 3.94753775E-05 2.2031 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970285267 ZNF619 zinc finger protein 619 0.00121389747 0.003314455243 2.2027 1.2979 1.2311 1.2317 1.1588 0.6526 1.07855892 RAD51D RAD51 paralog D 7.22866079E-06 3.13139142E-05 2.2019 0.7702 0.9416 0.8428 0.7311 1.1430 0.816655322 C5orf22 Q49AR2,chromosome 5 open reading frame 22 3.23744481E-07 1.8959805E-06 2.2016 3.3021 0.2621 0.6638 1.8102 0.2607 0.208764005 MYO1G myosin IG 3.88670034E-09 3.79774271E-08 2.2012 1.5647 2.0091 2.1109 1.1993 2.1343 2.09799533 POLR1C polymerase (RNA) I polypeptide C, 30kDa 2.23626487E-08 1.74843953E-07 2.2010 2.2501 31.1667 6.2748 1.5982 41.2677 3.95383508 IGHMBP2 immunoglobulin mu binding protein 2 3.76257256E-08 2.76710146E-07 2.2008 1.8357 0.1969 0.4489 0.7896 2.0873 0.3402

sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)

solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

pleckstrin homology domain containing, family M (with RUN domain) member 2

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 pseudogene

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)

9435 CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.0001604171 0.000526426244 2.2002 1.6649 2.7883 1.7459 1.7763 2.9194 3.3182286262 TPRN chromosome 9 open reading frame 75 7.05243989E-09 6.29209871E-08 2.2002 0.5624 2.6418 2.1944 0.5597 1.7094 2.9556113444 SMIM12 small integral membrane protein 12 9.97398909E-13 4.30838602E-11 2.1988 2.8627 3.2371 1.8317 1.7221 3.8763 1.8272100507588 TGFBR3L transforming growth factor, beta receptor III-like 0.01897163556 0.037695707363 2.1985 0.6190 1.3475 1.4432 0.3167 0.7304 1.3678284119 PTRF polymerase I and transcript release factor 0.00441393641 0.010534410405 2.1984 0.9417 1.3551 1.5605 0.4901 1.0464 1.345358526 MID1IP1 MID1 interacting protein 1 2.77367541E-08 2.10905523E-07 2.1981 2.4467 3.6922 1.6715 2.1948 3.9696 2.398294005 PIGS phosphatidylinositol glycan anchor biosynthesis, class S 1.54665769E-11 3.67975642E-10 2.1955 1.3739 0.8632 0.9552 1.0530 0.9324 1.190792815 HIST3H2A histone cluster 3, H2a 2.36100627E-06 1.13407746E-05 2.1953 4.4922 2.4511 0.7792 3.3174 2.6594 1.353130 ACAA1 acetyl-CoA acyltransferase 1 1.18415891E-10 1.91139148E-09 2.1953 2.1869 2.6823 1.5239 2.5028 7.7206 2.61357165 TPD52L2 tumor protein D52-like 2 6.41264038E-12 1.85815878E-10 2.1951 2.1358 2.2903 1.3911 1.9277 2.9819 2.5240402055 SRRD SRR1 domain containing 1.92652731E-07 1.19408097E-06 2.1949 0.6592 0.4444 1.4287 0.0873 0.2674 0.44349493 KIF23 kinesin family member 23 0.00055265385 0.001616470502 2.1945 0.6307 0.4660 0.8363 0.4719 0.4918 0.95042232 FDXR ferredoxin reductase 1.08595482E-07 7.13248259E-07 2.1944 0.9307 1.3073 1.3379 0.7899 1.6035 1.822051110 LACTB2 lactamase, beta 2 0.00015970134 0.000524737089 2.1938 19.6841 3.3717 0.9405 2.7071 4.7906 0.050359269 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 6.29675355E-05 0.000225464003 2.1929 1.3837 1.6034 1.7517 1.1274 1.4565 1.3999401409 RAB19 RAB19, member RAS oncogene family 0.00032973044 0.001015307472 2.1924 0.9470 1.7156 1.4788 0.8597 1.0467 1.1189148156 ZNF558 zinc finger protein 558 1.38710123E-05 5.64982471E-05 2.1922 0.6740 0.8599 0.7170 0.8001 0.8372 1.088285461 TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.00127504011 0.003462949108 2.1903 0.4378 0.4564 0.5193 0.3577 0.3725 0.477854732 TMED9 transmembrane emp24 protein transport domain containing 9 2.32599038E-10 3.4027619E-09 2.1903 1.8586 2.1841 1.3357 1.5136 2.0278 1.7188128240 APOA1BP apolipoprotein A-I binding protein 2.1970239E-11 4.91358882E-10 2.1901 2.3151 3.6724 2.0068 1.6656 4.9181 1.63438677 STX10 syntaxin 10 5.86627128E-06 2.58971995E-05 2.1897 12.2762 10.2336 2.9390 4.8648 7.4518 2.40471213 CLTC clathrin, heavy chain (Hc) 4.15446437E-09 4.02240113E-08 2.1892 2.1311 2.8308 1.9083 2.5902 5.6790 3.401129954 POMT2 protein-O-mannosyltransferase 2 0.0002527337 0.000798065692 2.1886 0.2000 0.1982 0.1812 0.2767 0.2338 0.178679961 DENND2D DENN/MADD domain containing 2D 4.97904158E-08 3.55517967E-07 2.1884 2.5905 2.0576 1.9068 2.4044 2.5210 1.9099100287482 SMKR1 small lysine-rich protein 1 0.00028969125 0.00090297484 2.1866 1.1693 1.2119 2.0618 0.7739 1.2268 1.25807376 NR1H2 nuclear receptor subfamily 1, group H, member 2 1.05801331E-10 1.74162334E-09 2.1858 1.0652 1.8816 1.9522 1.0741 2.8896 1.58737416 VDAC1 voltage-dependent anion channel 1 4.37345102E-08 3.17740346E-07 2.1845 1.2365 1.7159 1.1581 1.0515 2.1305 1.525979035 NABP2 nucleic acid binding protein 2 1.35706857E-07 8.70352995E-07 2.1841 2.0789 1.7671 2.3413 1.5543 1.2306 2.15339663 LPIN2 lipin 2 8.44245465E-10 1.01554004E-08 2.1831 1.6618 2.9347 1.6756 1.5525 2.7246 1.44432274 FHL2 four and a half LIM domains 2 0.00104100068 0.002879377002 2.1810 0.4167 0.3560 0.3841 0.5274 0.5798 0.435154998 AURKAIP1 aurora kinase A interacting protein 1 9.49311367E-11 1.58554089E-09 2.1797 1.3972 2.6651 1.6813 1.2512 4.8508 2.433855326 AGPAT5 Q9NUQ2,1-acylglycerol-3-phosphate O-acyltransferase 5 7.99706756E-09 7.0049098E-08 2.1792 2.2758 2.7030 1.7613 2.5541 3.5118 2.5937440 ASNS asparagine synthetase (glutamine-hydrolyzing) 6.76705574E-05 0.000240840753 2.1788 1.8550 1.2770 1.4689 1.4606 1.0282 1.700550855 PARD6A par-6 family cell polarity regulator alpha 2.59090573E-06 1.23219754E-05 2.1786 0.0206 0.4081 3.3422 0.0243 0.3635 0.793411336 EXOC3 exocyst complex component 3 3.47694107E-08 2.57313354E-07 2.1780 0.0823 0.4185 2.1202 0.0168 0.7091 0.69361108 CHD4 chromodomain helicase DNA binding protein 4 5.09220257E-11 9.53756288E-10 2.1779 1.7344 2.0909 2.1987 1.4999 3.4595 2.534956912 IFT46 intraflagellar transport 46 homolog (Chlamydomonas) 3.88621229E-06 1.78155409E-05 2.1774 1.8395 1.2760 2.1864 1.4213 1.2056 1.5930

471 ATIC 4.07697277E-09 3.95405766E-08 2.1767 1.9489 3.1420 1.7173 1.8026 3.9988 1.553828969 BZW2 basic leucine zipper and W2 domains 2 2.38010953E-08 1.84305226E-07 2.1760 2.1360 1.2704 1.5008 1.3839 1.4842 1.890384883 AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 2.29698191E-05 8.93558728E-05 2.1759 0.3430 1.8957 0.7710 0.2385 1.0736 0.621822905 EPN2 epsin 2 0.00024416828 0.000772811841 2.1758 0.5538 1.0334 0.8504 0.4596 0.8532 0.942557019 CIAPIN1 cytokine induced apoptosis inhibitor 1 4.30389162E-11 8.33058345E-10 2.1752 0.2402 2.0383 0.9036 0.3668 1.9086 0.613684311 MRPL45 mitochondrial ribosomal protein L45 6.55724929E-08 4.55220589E-07 2.1748 1.7899 2.6875 1.9143 1.7759 4.1108 2.5544348995 NUP43 nucleoporin 43kDa 4.19746525E-09 4.05193582E-08 2.1747 1.0684 1.6432 0.7515 0.7756 1.2990 0.73856199 RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 3.94061086E-10 5.31447785E-09 2.1713 0.9260 0.9651 1.2362 1.0356 1.3711 1.4350646023 ADORA2A-AS1 hypothetical protein LOC646023 0.00303042135 0.00753358625 2.1712 0.0720 0.0639 0.2644 0.6459 0.0434 0.1385387496 RASL11A RAS-like, family 11, member A 0.00221185069 0.005675076744 2.1712 0.9641 2.0155 1.6720 0.8583 2.5685 2.054054733 SLC35F2 solute carrier family 35, member F2 1.61044127E-06 8.03549503E-06 2.1707 2.6360 2.2938 2.1115 1.9712 2.4296 2.51564134 MAP4 microtubule-associated protein 4 2.84038697E-12 9.69446082E-11 2.1703 0.3586 0.2526 0.4096 0.5352 0.4331 0.70588676 STX11 syntaxin 11 3.78454603E-05 0.000141442473 2.1694 2.6125 2.2544 1.9982 3.0225 2.9278 2.1401169200 TMEM64 transmembrane protein 64 3.14073596E-07 1.84525812E-06 2.1694 0.8666 1.3124 0.7298 0.8486 1.4251 1.2533729440 CCDC61 hypothetical protein LOC729440 7.96322833E-06 3.4212111E-05 2.1691 2.1741 1.4267 1.8194 1.5529 2.3866 1.7217126526 C19orf47 chromosome 19 open reading frame 47 1.7485011E-08 1.40338397E-07 2.1690 0.8333 1.5182 2.8738 0.5969 4.3700 1.25586499 SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 2.97885441E-11 6.22572065E-10 2.1679 0.4449 1.7926 0.5811 0.3803 0.7706 0.628254958 TMEM160 transmembrane protein 160 6.06577755E-11 1.1050238E-09 2.1676 1.2171 1.7957 1.1139 0.8664 1.2964 1.379691768 CABLES1 Cdk5 and Abl enzyme substrate 1 0.00469657505 0.01113334448 2.1668 0.4773 0.9816 1.0348 0.3474 0.6009 0.772410318 TNIP1 TNFAIP3 interacting protein 1 1.16271173E-10 1.89013067E-09 2.1666 0.7684 1.4021 1.2564 0.7191 1.4517 1.254210380 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2.36762723E-05 9.17719237E-05 2.1659 2.7190 3.0687 1.9393 2.8845 4.5648 2.603210432 RBM14 RNA binding motif protein 14 1.78681877E-06 8.83114757E-06 2.1654 0.3321 0.3321 0.3321 0.3970 0.3970 0.397030837 SOCS7 suppressor of cytokine signaling 7 4.38322834E-07 2.48265183E-06 2.1654 1.9351 2.0734 2.0192 1.3942 1.9304 2.0826100287932 TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 9.93076939E-08 6.5768401E-07 2.1647 2.6015 2.1597 2.4061 3.1256 3.2921 3.240429777 ABT1 activator of basal transcription 1 2.56560384E-11 5.5741633E-10 2.1644 1.8307 2.5392 1.9575 1.9010 4.1093 3.04846059 ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 2.57190728E-08 1.97287531E-07 2.1644 1.4024 3.5743 1.2650 1.2994 0.5696 0.7100197407 ZNF48 zinc finger protein 48 9.18509649E-11 1.54967759E-09 2.1635 1.7358 2.7657 1.9978 1.7289 3.0005 2.2785282969 FUOM chromosome 10 open reading frame 125 5.58588381E-05 0.000201869598 2.1617 1.0544 2.1457 0.9738 0.9391 3.0038 1.965829904 EEF2K eukaryotic elongation factor-2 kinase 8.32415841E-10 1.00263034E-08 2.1609 1.1998 2.0595 1.5140 1.3617 3.3292 2.17212733 GLE1 GLE1 RNA export mediator 1.18844974E-10 1.91493418E-09 2.1609 2.8599 2.0551 1.8696 2.6042 2.6898 2.903455695 NSUN5 NOP2/Sun domain family, member 5 3.10869487E-13 1.88711205E-11 2.1604 2.1389 1.7926 1.3784 1.8726 1.7678 1.58153419 IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 6.47975269E-07 3.5227028E-06 2.1599 1.0266 1.0239 0.9589 0.9289 1.0506 0.856454676 GTPBP2 GTP binding protein 2 2.20581706E-07 1.34609309E-06 2.1587 1.0226 0.5745 2.7517 0.6307 0.8884 1.7711706 TSPO translocator protein (18kDa) 1.37125605E-07 8.7914353E-07 2.1584 1.5252 2.3368 1.8436 1.2935 3.3920 2.1907253714 MMS22L chromosome 6 open reading frame 167 7.47188746E-07 4.00477295E-06 2.1567 2.3354 2.8115 1.6322 1.8929 3.0437 2.191510557 RPP38 ribonuclease P/MRP 38kDa subunit 1.96261377E-06 9.60130625E-06 2.1564 0.3426 0.4871 0.3070 0.2277 0.5383 0.210979917 MAGIX MAGI family member, X-linked 0.00521754461 0.012214602822 2.1563 0.6792 0.7814 0.9235 0.4572 0.4957 0.630425822 DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.00011493602 0.000389764344 2.1562 1.3240 1.3989 2.1014 1.2062 1.1111 2.32658683 SRSF9 serine/arginine-rich splicing factor 9 1.65489626E-08 1.33716836E-07 2.1560 25.7604 1.5768 0.8969 24.3069 2.4327 1.2095400506 KNOP1 lysine-rich nucleolar protein 1 1.46971784E-05 5.95183607E-05 2.1554 2.5714 1.6566 5.6801 1.7952 1.3357 3.85476504 SLAMF1 signaling lymphocytic activation molecule family member 1 7.71491047E-07 4.11822507E-06 2.1550 4.0640 2.2102 2.1923 4.3009 2.9885 2.15085546 PRCC papillary renal cell carcinoma (translocation-associated) 6.97555672E-11 1.23624997E-09 2.1549 3.5321 6.5806 2.4271 2.9567 10.6288 4.421610361 NPM2 nucleophosmin/nucleoplasmin 2 0.01816320307 0.036290655713 2.1543 0.7266 1.3690 1.0782 0.5982 1.0836 0.841979691 QTRTD1 queuine tRNA-ribosyltransferase domain containing 1 8.63375665E-07 4.56205904E-06 2.1533 0.9208 0.5462 1.0727 0.3868 0.3336 0.5183

440081 DDX12P 3.82903299E-07 2.20289959E-06 2.1518 0.6150 0.8902 0.8172 0.7565 0.9308 0.8884339929 LPP-AS2 LPP antisense RNA 2 0.02490829174 0.047710568019 2.1506 1.0845 4.0029 4.5829 1.3212 1.3631 3.402451604 PIGT phosphatidylinositol glycan anchor biosynthesis, class T 9.60717688E-13 4.17957943E-11 2.1499 1.4157 1.2624 1.2517 1.2587 1.4463 1.360279934 ADCK4 aarF domain containing kinase 4 3.222334E-07 1.88894728E-06 2.1497 0.7751 0.9781 1.3446 0.6909 0.9964 1.0426740 MRPL49 mitochondrial ribosomal protein L49 4.05005312E-11 7.90950479E-10 2.1497 0.3010 1.6683 0.9123 0.5665 9.0882 0.589451477 ISYNA1 inositol-3-phosphate synthase 1 2.63177164E-06 1.24968117E-05 2.1493 0.7338 2.8234 1.1198 0.5577 2.2124 0.87848775 NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 5.89791847E-07 3.23623923E-06 2.1493 1.6200 2.4985 3.0644 1.3435 3.6464 3.67331676 DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 5.42717174E-08 3.83025423E-07 2.1482 2.9162 1.6849 1.6768 2.1856 1.5183 1.64915428 POLG polymerase (DNA directed), gamma 7.84392487E-10 9.51687884E-09 2.1476 1.9911 2.9224 2.4144 2.3095 4.0256 2.79499219 MTA2 metastasis associated 1 family, member 2 2.97719004E-11 6.22572065E-10 2.1467 1.6794 2.2948 1.9873 1.8345 3.3446 2.687864210 MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 1.45994166E-11 3.52391731E-10 2.1458 0.6338 0.8671 0.5910 0.5325 0.6661 0.679551602 NOP58 NOP58 ribonucleoprotein 1.9983794E-09 2.11550954E-08 2.1456 2.5071 2.4761 2.4093 3.4427 4.8795 4.85681072 CFL1 cofilin 1 (non-muscle) 3.63004196E-09 3.56411213E-08 2.1453 3.0011 3.7446 1.7060 2.4076 3.8588 2.7394

10629 TAF6L 9.95007566E-08 6.58723849E-07 2.1451 1.6288 1.9590 2.4888 1.3931 2.8716 2.519526973 CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 2.99845915E-07 1.76963326E-06 2.1441 1.8862 3.8827 1.6387 2.0843 4.5399 2.05321663 DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 1.66330918E-07 1.04691648E-06 2.1429 0.1339 0.1482 0.1791 0.2503 0.2985 0.260223132 RAD54L2 RAD54-like 2 (S. cerevisiae) 1.99682016E-08 1.58221587E-07 2.1413 0.3652 0.4512 0.2698 0.3203 0.1878 0.2178654322 SNORA13 small nucleolar RNA, H/ACA box 13 0.02090919734 0.041041234697 2.1412 1.7674 8.3519 2.0538 1.0345 7.4736 1.620629890 RBM15B RNA binding motif protein 15B 5.89534442E-12 1.74808518E-10 2.1403 2.2509 2.5990 1.5950 1.3632 3.9596 1.3644204 AK2 adenylate kinase 2 8.11114995E-08 5.50750397E-07 2.1392 2.2951 2.0068 1.6986 1.7194 3.0456 2.101355353 LAPTM4B lysosomal protein transmembrane 4 beta 0.00011516429 0.000390382025 2.1383 1.6241 1.9117 2.0771 1.2589 1.8677 2.2947317781 DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 6.6739542E-09 6.0339679E-08 2.1380 0.9190 3.4409 7.3480 0.6737 2.3812 6.753411138 TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00124315148 0.003384721168 2.1379 0.8934 0.9245 0.7982 0.7184 0.8855 0.7707283989 TSEN54 tRNA splicing endonuclease 54 homolog (S. cerevisiae) 4.9364202E-10 6.41523967E-09 2.1377 2.1056 3.0066 1.4359 1.8992 7.7693 1.4868112950 MED8 mediator complex subunit 8 1.38344575E-09 1.55081722E-08 2.1369 1.2046 0.8672 4.4076 0.4457 0.4496 0.512755651 NHP2 NHP2 ribonucleoprotein 4.48315203E-07 2.52905693E-06 2.1369 1.6044 1.0125 1.3632 1.3444 1.9115 1.795055746 NUP133 nucleoporin 133kDa 3.01207063E-12 1.01543459E-10 2.1366 2.1829 1.9904 2.3823 1.6101 2.1938 2.738751264 MRPL27 mitochondrial ribosomal protein L27 5.59653982E-08 3.93761939E-07 2.1352 1.4435 1.6901 0.7866 2.5800 0.7642 0.8455

9013 TAF1C 1.64534906E-08 1.3314357E-07 2.1351 0.9996 1.8707 1.4426 1.2333 2.8527 1.654957478 USP31 ubiquitin specific peptidase 31 2.4740831E-07 1.4888694E-06 2.1346 0.5012 0.5824 0.5550 0.5087 0.6795 0.557351291 GMIP GEM interacting protein 3.77345279E-10 5.14157564E-09 2.1346 1.3616 1.8054 1.8247 1.5168 2.0867 2.1833

728758 PIN4P1 0.01513399061 0.031004403681 2.1345 0.0395 0.0789 0.1792 0.0747 0.3763 0.090284775 ZNF607 zinc finger protein 607 0.00377192741 0.009155241454 2.1342 1.4528 1.2452 1.4319 1.2258 1.5036 1.6497908 CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 8.73067087E-08 5.87359419E-07 2.1333 2.5782 8.1336 1.3332 0.7189 6.5523 0.853123185 LARP4B La ribonucleoprotein domain family, member 4B 1.06359523E-11 2.73718478E-10 2.1321 1.3792 0.8685 1.1672 1.7150 1.2856 2.34781845 DUSP3 dual specificity phosphatase 4 0.00097956407 0.002728028458 2.1288 2.0303 3.7157 2.1078 2.0016 5.3258 3.0811144455 E2F7 E2F transcription factor 7 0.00545555015 0.012690491714 2.1285 0.5985 0.9630 0.8629 0.6407 1.0394 0.9787149175 MANEAL mannosidase, endo-alpha-like 0.00055673856 0.001627375938 2.1283 0.4707 0.7167 1.0945 0.3928 0.3090 0.581791442 C19orf40 chromosome 19 open reading frame 40 0.00066010929 0.001898554537 2.1279 0.4417 0.1740 0.4949 0.5334 0.1117 0.571030833 NT5C 5', 3'-nucleotidase, cytosolic 4.75828923E-08 3.41356344E-07 2.1266 1.3085 2.4075 1.4207 1.3178 3.9160 2.1420162979 ZNF296 zinc finger protein 296 0.00034776167 0.001064728748 2.1258 1.3427 2.5620 2.0516 1.0153 2.6307 1.581323061 TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 4.29059651E-10 5.70165668E-09 2.1246 0.5512 0.7165 0.7587 0.4122 0.7577 0.920780324 PUS1 pseudouridylate synthase 1 3.92499333E-09 3.82901645E-08 2.1244 0.8627 1.9118 1.2523 0.5866 2.5934 1.362184717 HDGFRP2 hepatoma-derived growth factor-related protein 2 5.99354672E-10 7.58933372E-09 2.1243 0.7074 1.0026 1.0740 0.6387 1.1412 1.28645155 PDGFB platelet-derived growth factor beta polypeptide 0.02551158783 0.048673497835 2.1241 1.3261 1.1003 1.0714 0.7548 0.5728 0.663183694 RPS6KL1 ribosomal protein S6 kinase-like 1 0.000338113 0.001038493976 2.1238 0.3057 0.7124 0.4898 0.2907 0.8307 0.416023550 PSD4 pleckstrin and Sec7 domain containing 4 1.73714027E-09 1.88503274E-08 2.1233 1.1051 1.0263 1.0239 1.0354 0.9999 1.0373157570 ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.00981100715 0.021280475156 2.1220 1.3112 0.9505 1.1317 0.7767 0.7524 1.59968833 GMPS guanine monphosphate synthase 6.79970804E-09 6.13249089E-08 2.1203 1.1251 3.4421 1.5144 1.2098 2.7393 2.132210948 STARD3 StAR-related lipid transfer (START) domain containing 3 4.29882387E-10 5.70429265E-09 2.1162 1.5481 1.3071 1.4371 1.3396 2.2220 1.404684285 EIF1AD eukaryotic translation initiation factor 1A domain containing 5.72682317E-10 7.3021991E-09 2.1161 3.1947 1.6309 1.9128 1.2552 2.3393 4.304928982 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 9.038955E-05 0.000313396178 2.1141 3.6735 3.8140 2.8455 1.2025 1.7421 2.294829920 PYCR2 pyrroline-5-carboxylate reductase family, member 2 7.55611249E-09 6.67304434E-08 2.1140 1.0945 1.0541 1.5262 1.0028 1.0011 0.850464785 GINS3 GINS complex subunit 3 (Psf3 homolog) 0.00064944215 0.001869345764 2.1129 1.3271 1.4589 1.6702 1.3462 2.4271 2.202510609 LEPREL4 leprecan-like 4 0.00055574894 0.001624743155 2.1125 1.9566 4.4575 2.1510 2.1683 3.4852 2.12139784 SNX17 sorting nexin 17 8.28082513E-12 2.25287446E-10 2.1124 1.7042 1.9895 3.0659 1.0727 2.5629 1.6655283335 LOC283335 hypothetical protein LOC283335 0.0069534733 0.015695350737 2.1120 1.3768 1.8708 1.0754 1.3405 1.8621 1.3152131076 CCDC58 coiled-coil domain containing 58 0.00031728691 0.000980958772 2.1119 2.0257 1.8862 2.2856 2.4110 3.4004 2.3723

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 (CHL1-like helicase homolog, S. cerevisiae)

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa

protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 pseudogene 1

283848 CES4A hypothetical protein FLJ37464 0.00271247549 0.006819255927 2.1108 0.2800 0.4467 0.9148 0.3002 0.4451 0.94103306 HSPA2 heat shock 70kDa protein 2 7.45344055E-05 0.00026326941 2.1107 2.0494 2.1154 2.1245 1.7253 2.2714 2.16547918 GPANK1 G patch domain and ankyrin repeats 1 2.01381142E-09 2.12941912E-08 2.1091 0.6027 0.7939 0.6418 0.5764 0.6756 0.735226048 ZNF500 zinc finger protein 500 1.15115951E-05 4.76744934E-05 2.1090 1.2260 2.1137 1.9213 1.1525 2.2262 1.72055153 PDE1B phosphodiesterase 1B, calmodulin-dependent 0.00025439294 0.000802671003 2.1071 1.5527 1.0392 1.4463 1.1108 0.9380 0.908660626 RIC8A RIC8 guanine nucleotide exchange factor A 1.70819535E-11 4.00155712E-10 2.1064 1.6221 1.2336 1.6287 1.7408 3.1218 2.16829764 KIAA0513 KIAA0513 3.88070064E-06 1.77982334E-05 2.1060 1.8851 1.2683 1.5764 1.0833 1.9080 1.68785357 PLS1 plastin 1 0.00234843239 0.005991420913 2.1057 0.8618 0.8708 0.6903 0.7817 0.6821 0.73322302 FOXJ1 forkhead box J1 0.00689122288 0.015583570498 2.1057 0.9139 2.5332 1.4191 0.5408 0.8654 0.569410093 ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 3.67692954E-11 7.35064077E-10 2.1055 2.4792 0.4946 1.4312 0.3906 0.4406 1.138426507 CNNM1 cyclin M1 0.00233009005 0.005947947105 2.1054 0.3286 0.6871 0.6518 0.3968 0.9406 0.64066533 SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 2.95110201E-06 1.38653988E-05 2.1052 2.0602 2.3357 1.3081 1.8238 2.8482 2.07174501 MT1X metallothionein 1X 1.4964439E-06 7.51181947E-06 2.1051 1.9967 2.6021 2.0123 1.9382 3.1608 1.649264114 TMBIM1 transmembrane BAX inhibitor motif containing 1 6.83157296E-10 8.46439166E-09 2.1047 2.6994 3.1824 2.1857 1.6611 3.3631 1.81994493 MT1E metallothionein 1E 0.00551435196 0.012807708028 2.1036 1.6436 2.1093 2.0600 1.5868 1.7815 1.597051121 RPL26L1 ribosomal protein L26-like 1 4.69019991E-08 3.36868447E-07 2.1036 4.2191 0.2553 1.0563 6.3181 0.2539 0.378157109 REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) 2.21649848E-11 4.95108316E-10 2.1029 1.2467 1.8660 2.2788 1.4611 2.7305 3.1712129880 BBS5 Bardet-Biedl syndrome 5 0.00036296423 0.001105531324 2.1015 0.3321 0.3321 0.3321 0.3970 0.3970 0.39709631 NUP155 nucleoporin 155kDa 1.47363086E-06 7.40672091E-06 2.1010 2.8853 2.7733 2.4397 2.5694 3.8136 2.677424144 TFIP11 tuftelin interacting protein 11 1.02953916E-12 4.41590128E-11 2.1000 1.1756 1.1282 1.1273 1.1411 1.3533 1.24328907 AP1M1 adaptor-related protein complex 1, mu 1 subunit 5.33694497E-12 1.61451421E-10 2.0994 1.7111 1.6485 1.7500 1.4670 1.7518 1.883783892 KCTD10 potassium channel tetramerization domain containing 10 4.63265567E-10 6.09855075E-09 2.0988 2.1314 1.1315 1.9028 1.3487 0.7331 0.833780023 NRSN2 neurensin 2 0.00030183803 0.000937956553 2.0984 0.3800 0.8446 1.3681 0.2871 1.0610 1.238910294 DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 5.55412143E-11 1.02613657E-09 2.0984 3.2056 4.3142 2.1134 2.5957 4.9157 2.66495690 PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 2.57064998E-10 3.71899575E-09 2.0978 1.0476 0.7308 1.0984 1.0045 1.5003 1.1852646329 LOC646329 uncharacterized LOC646329 0.00127510517 0.003462949108 2.0977 3.0793 3.1698 1.8656 2.4236 4.2359 1.323422822 PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00031201074 0.000966117635 2.0972 1.8041 1.8910 2.4233 1.1335 1.9087 3.85988969 HIST1H2AG histone cluster 1, H2ag 5.66392508E-06 2.50948688E-05 2.0970 8.9368 0.7542 5.7622 2.3108 0.4982 2.8916253639 ZNF620 zinc finger protein 620 0.00030757585 0.000953744181 2.0962 1.1159 1.1769 1.0296 1.1803 1.6957 0.96822617 GARS glycyl-tRNA synthetase 1.7863859E-06 8.83114757E-06 2.0951 2.3178 2.9796 0.7269 0.6104 0.7357 0.3395113829 SLC35A4 solute carrier family 35, member A4 5.65029278E-11 1.03969939E-09 2.0941 1.3726 5.0413 2.3680 0.3992 4.7741 0.990310156 RASA4 RAS p21 protein activator 4 2.70851668E-09 2.76171969E-08 2.0939 0.5578 0.6543 0.6445 0.4418 1.1887 0.456510965 ACOT2 acyl-CoA thioesterase 2 3.06183347E-06 1.43340561E-05 2.0937 2.4177 3.7043 2.0076 2.0509 4.7230 1.866378996 C7orf49 chromosome 7 open reading frame 49 7.40376392E-12 2.06536755E-10 2.0934 1.4947 1.8518 1.6516 0.9380 1.4210 1.49841857 DVL3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1.05610889E-10 1.74162334E-09 2.0934 0.8983 1.3321 1.4431 0.7783 1.3136 1.319855308 DDX19A Q9NUU7,B4DRZ7,DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 6.13166853E-11 1.1138693E-09 2.0926 0.4159 0.8737 0.9367 1.0740 0.5762 0.592258472 SQRDL sulfide quinone reductase-like (yeast) 1.17593044E-08 9.85171985E-08 2.0925 0.9828 1.1976 1.0733 0.9808 1.7810 1.18951312 COMT catechol-O-methyltransferase 3.74347425E-08 2.75476285E-07 2.0918 0.2438 0.3736 0.3574 0.0990 0.1909 0.29705883 RAD9A RAD9 homolog A (S. pombe) 1.18536087E-06 6.07884196E-06 2.0917 1.2470 1.0014 1.6753 1.1346 1.9263 1.67183614 IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 3.34081871E-09 3.31938224E-08 2.0897 1.6046 1.8061 2.2266 1.3388 1.9587 1.770754440 SASH3 SAM and SH3 domain containing 3 1.63372848E-09 1.78922826E-08 2.0892 2.0027 1.5492 1.4124 1.7593 1.4800 1.49839064 MAP3K6 mitogen-activated protein kinase kinase kinase 6 0.00050903091 0.001500647435 2.0880 0.7575 0.8752 1.0491 0.3452 0.8759 0.973523392 KIAA0368 KIAA0368 5.53681428E-10 7.09457718E-09 2.0878 1.4728 2.1663 1.2559 1.2183 2.4698 1.80116720 SREBF1 sterol regulatory element binding transcription factor 1 3.99010052E-07 2.27977226E-06 2.0871 0.8933 1.0547 1.8988 0.6476 0.9846 1.546764411 ARAP3 centaurin, delta 3 0.00151020454 0.004034277394 2.0869 0.4456 0.4286 0.6786 0.3804 0.3044 0.540211128 POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 1.18515701E-11 2.9718682E-10 2.0869 2.2333 2.3111 1.9461 1.7622 2.7860 2.30757916 PRRC2A proline-rich coiled-coil 2A 4.95616852E-11 9.33599085E-10 2.0864 0.6253 0.6543 0.5439 0.6304 0.8622 0.8147407975 MIR17HG miR-17-92 cluster host gene (non-protein coding) 0.00031115116 0.000963619309 2.0859 2.6229 4.7222 1.5940 1.7837 4.4324 2.463623218 NBEAL2 neurobeachin-like 2 4.84744919E-07 2.71029962E-06 2.0857 0.8601 1.5555 1.1486 0.7481 1.1576 0.9828100533955 SENP3-EIF4A1 SENP3-EIF4A1 readthrough 7.75240919E-10 9.42461881E-09 2.0852 0.9840 0.9409 1.1569 0.9032 1.3369 1.3154115207 KCTD12 potassium channel tetramerization domain containing 12 0.01928308885 0.038239700392 2.0851 1.7255 1.2386 1.5658 1.5599 1.6849 2.243384705 GTPBP3 GTP binding protein 3 (mitochondrial) 2.1774099E-08 1.71047436E-07 2.0849 1.6257 2.1417 1.4426 1.2436 2.5709 1.6991643 CXCR5 chemokine (C-X-C motif) receptor 5 0.0045973183 0.010924983742 2.0841 0.9331 0.7812 1.7977 0.4928 0.6383 0.919264216 TFB2M transcription factor B2, mitochondrial 5.64489058E-08 3.96858179E-07 2.0841 1.7124 1.9281 3.6706 1.0782 1.7757 1.2777284023 LOC284023 hypothetical protein LOC284023 0.00047229739 0.001401171943 2.0833 1.9295 2.3844 2.2473 1.1514 3.5340 2.46935694 PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 8.50107329E-10 1.02057563E-08 2.0829 1.8394 1.5352 1.6641 1.4861 2.1949 1.76689329 GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 1.60885857E-07 1.01509198E-06 2.0823 1.0140 3.9234 0.9660 1.2859 8.9752 1.234884978 FRMD5 FERM domain containing 5 0.02323212595 0.044901354491 2.0818 0.4596 0.4728 0.5487 0.4628 0.2193 0.5087285367 RPUSD3 RNA pseudouridylate synthase domain containing 3 1.1929653E-11 2.98181911E-10 2.0812 1.7831 2.7303 2.4414 1.6421 3.0243 2.573010045 SH2D3A SH2 domain containing 3A 1.88688044E-05 7.47713713E-05 2.0810 2.1606 2.6100 1.9383 1.6454 3.0604 2.01556195 RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 6.24275657E-11 1.1264569E-09 2.0806 1.1196 1.8059 2.2456 0.7190 1.4249 1.69683609 ILF3 interleukin enhancer binding factor 3, 90kDa 2.91916497E-10 4.1504582E-09 2.0783 2.0614 1.2102 0.5782 1.6767 3.7789 0.780060490 PPCDC phosphopantothenoylcysteine decarboxylase 0.00038033537 0.001153250565 2.0767 0.8904 1.0993 1.7839 1.0402 1.2676 1.6390124583 CANT1 calcium activated nucleotidase 1 1.34650456E-11 3.31206095E-10 2.0757 1.2310 2.5157 1.7594 0.9933 2.6356 1.8865285966 FAM115C hypothetical protein FLJ40722 3.55902802E-09 3.50758145E-08 2.0748 1.5248 1.2971 1.1576 1.4065 1.6658 1.2210116988 AGAP3 centaurin, gamma 3 1.49759834E-06 7.5155498E-06 2.0742 0.3175 0.2716 0.4895 0.2081 0.1968 0.50628694 DGAT1 diacylglycerol O-acyltransferase 1 5.46765832E-12 1.64317521E-10 2.0740 1.6947 1.2836 1.9225 0.9919 1.8349 2.127423129 PLXND1 plexin D1 0.0211711193 0.041475146547 2.0728 0.3642 0.6118 0.5700 0.3058 0.3945 0.404028998 MRPL13 mitochondrial ribosomal protein L13 1.20300952E-07 7.80866425E-07 2.0723 0.3543 0.0435 0.0959 0.1055 0.0640 0.30729093 DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 1.90503621E-09 2.03918111E-08 2.0718 1.9886 2.0306 1.9383 2.5195 2.8653 3.321057003 CCDC47 coiled-coil domain containing 47 4.28660807E-09 4.12453411E-08 2.0710 2.8706 2.0104 2.4318 2.1339 3.4887 2.88195770 PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.50982871E-11 3.61567368E-10 2.0706 2.5944 1.7431 2.0500 2.2307 2.4583 2.6014

10775 POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 8.85793201E-10 1.05647607E-08 2.0703 2.0583 2.3724 1.9537 2.4192 4.2899 2.9563353174 ZACN zinc activated ligand-gated ion channel 0.02097961783 0.041152933645 2.0702 0.5749 0.4499 0.5934 0.2505 0.1391 0.340264755 C16orf58 chromosome 16 open reading frame 58 1.92328567E-09 2.05418376E-08 2.0695 1.4229 1.7179 1.1857 1.2768 2.0762 1.606258490 RPRD1B regulation of nuclear pre-mRNA domain containing 1B 2.69973035E-08 2.06054607E-07 2.0688 1.1220 2.1232 1.4276 0.8263 1.2460 0.913911021 RAB35 RAB35, member RAS oncogene family 2.02213372E-10 3.01128177E-09 2.0678 2.5108 2.3895 2.8060 2.0979 2.9447 3.5749

10248 POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 1.81337512E-07 1.13008152E-06 2.0676 1.5144 2.6610 2.2505 1.6972 4.7667 3.501279892 MCMBP minichromosome maintenance complex binding protein 1.1655979E-09 1.34032755E-08 2.0671 1.0038 1.0794 0.8960 1.1790 1.3562 1.1472310 ANXA7 annexin A7 3.16946404E-11 6.5390294E-10 2.0668 3.6164 2.7797 1.8561 3.3120 3.2118 2.304927141 CIDEB cell death-inducing DFFA-like effector b 5.09449506E-11 9.53756288E-10 2.0665 0.2916 0.4511 0.3943 0.3500 0.2571 0.33129735 KNTC1 kinetochore associated 1 1.56310685E-05 6.30070338E-05 2.0664 2.6056 2.4570 4.0251 0.8928 1.6570 1.901423264 ZC3H7B zinc finger CCCH-type containing 7B 2.26802011E-09 2.35998083E-08 2.0660 1.4893 1.4581 1.4463 1.0731 1.9576 1.692792806 CENPBD1 hypothetical protein MGC16385 0.00121071515 0.003306260232 2.0659 2.9236 5.4170 4.0398 1.3383 4.1096 1.71128940 TOP3B topoisomerase (DNA) III beta 2.54643529E-08 1.95497755E-07 2.0655 0.8485 1.8501 0.8983 0.6514 1.9924 0.93719904 RBM19 RNA binding motif protein 19 1.68557884E-08 1.35857506E-07 2.0652 2.8799 3.0408 2.2424 2.4802 3.2881 1.76187094 TLN1 talin 1 9.72667959E-11 1.6156899E-09 2.0650 0.3321 0.3321 0.3321 0.3970 0.3970 0.397079879 CCDC134 coiled-coil domain containing 134 2.32172642E-05 9.02032431E-05 2.0649 2.6348 2.1756 2.2672 2.6015 2.5771 2.924557089 ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 3.10785045E-05 0.000117692525 2.0647 0.6464 5.5657 2.1114 0.3006 0.8331 0.94509344 TAOK2 TAO kinase 2 1.53088859E-08 1.24709747E-07 2.0639 0.6764 0.7410 0.7329 0.5793 0.7953 0.82456891 TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 6.2814405E-09 5.7158606E-08 2.0637 0.4633 0.7028 0.4876 0.4791 0.7385 0.5321150946 GAREML GRB2 associated, regulator of MAPK1-like 0.00169027795 0.004458619888 2.0633 0.5954 1.3907 0.5485 0.2529 1.4030 0.497084437 MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils 3.67290771E-06 1.69429776E-05 2.0633 1.6892 3.4690 1.2383 1.7600 3.6448 1.3797257396 LOC257396 hypothetical protein LOC257396 0.01302154961 0.027204408241 2.0632 0.7975 0.4578 0.7290 0.1927 0.6260 0.58221778 DYNC1H1 dynamin 2 6.58617174E-11 1.17407346E-09 2.0629 0.4027 0.9016 0.6256 0.4452 1.4477 1.005953342 IL17D interleukin 17D 0.0098327657 0.021315018963 2.0627 3.0367 2.8007 1.3759 1.6678 1.9082 1.305910280 SIGMAR1 sigma non-opioid intracellular receptor 1 1.77025218E-08 1.41806435E-07 2.0626 1.8710 1.9082 2.2331 1.1528 3.1853 2.725726128 KIAA1279 KIAA1279 5.05040621E-06 2.26223926E-05 2.0614 1.8521 2.0367 1.5601 1.7435 2.3278 1.8726286442 LOC286442 hypothetical protein LOC286442 0.00440503223 0.010516197065 2.0611 2.0284 3.3217 1.8704 1.9112 3.6779 1.563110919 EHMT2 euchromatic histone-lysine N-methyltransferase 2 1.6423056E-10 2.51325025E-09 2.0608 0.3367 0.3237 0.3995 0.3903 0.3597 0.397660678 EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 2.14269101E-11 4.81565193E-10 2.0565 1.0769 0.6225 1.1690 0.5005 0.1810 0.460879791 FBXO31 F-box protein 31 1.25546492E-11 3.11682814E-10 2.0565 0.7728 2.1270 0.6226 1.0657 2.0303 0.919485453 TSPYL5 TSPY-like 5 0.0005002934 0.001477511061 2.0565 0.6224 1.6721 1.0124 0.7313 1.5458 1.00804682 NUBP1 nucleotide binding protein 1 1.88964417E-08 1.50709639E-07 2.0555 1.6378 1.1233 1.6513 1.1942 1.1936 1.698225960 GPR124 G protein-coupled receptor 124 0.00331464248 0.008151433023 2.0555 0.7191 0.9083 1.2679 0.5638 0.8431 1.080879723 SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 9.64696399E-05 0.000332520894 2.0551 2.1015 3.0171 1.4800 1.6540 3.6931 2.822855361 PI4K2A phosphatidylinositol 4-kinase type 2 alpha 4.84063081E-10 6.3222306E-09 2.0551 0.6606 0.8319 0.6914 0.7229 0.8600 0.851979142 PHF23 PHD finger protein 23 2.80327212E-09 2.85038331E-08 2.0550 1.4904 1.9024 1.5773 1.5560 3.2367 2.1396166793 ZBTB49 zinc finger protein 509 0.00094384591 0.002636995778 2.0541 0.9203 1.2511 0.4433 0.3830 0.7621 0.5863

4298 MLLT1 3.58194577E-10 4.91730377E-09 2.0533 1.3955 2.1552 1.8252 1.0107 2.4772 1.7344156 ADRBK1 adrenergic, beta, receptor kinase 1 2.51217051E-11 5.47108219E-10 2.0530 1.5454 1.3221 1.5693 1.7414 1.8269 2.134410245 TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 1.91925144E-10 2.86976779E-09 2.0527 0.3321 0.3321 0.3321 0.3970 0.3970 0.397057175 CORO1B coronin, actin binding protein, 1B 1.18696643E-06 6.08536771E-06 2.0526 2.1452 2.3300 1.7435 1.0861 1.1524 1.241435 ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 5.72440137E-10 7.3021991E-09 2.0513 1.7708 1.8871 1.6768 1.4285 1.6425 1.633780086 TUBA4B tubulin, alpha 4b (pseudogene) 0.00077232623 0.002195386578 2.0511 2.1874 2.4816 3.2980 2.0855 2.3072 2.791951161 C3orf18 chromosome 3 open reading frame 18 6.38233524E-05 0.00022817067 2.0510 0.8932 1.5970 2.7626 0.6031 0.8558 2.219464858 DCLRE1B DNA cross-link repair 1B 0.00042517863 0.001274001947 2.0509 1.2915 35.7986 1.1411 0.2433 8.2326 0.786110445 MCRS1 microspherule protein 1 2.87701004E-11 6.09139368E-10 2.0501 1.7342 2.2031 1.8720 1.8348 2.8510 2.62425901 RAN RAN, member RAS oncogene family 6.54160692E-08 4.54480006E-07 2.0499 2.5651 2.9328 2.2216 1.9551 4.0247 2.7134402 ARL2 ADP-ribosylation factor-like 2 2.80831105E-11 5.97362741E-10 2.0492 0.3321 0.3321 0.3321 0.3970 0.3970 0.39701820 ARID3A atrophin 1 4.67928692E-07 2.6307671E-06 2.0492 1.7472 3.5537 2.7766 1.5481 5.1751 5.02023320 HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.386424E-07 8.87933379E-07 2.0487 1.1982 9.1140 1.4111 1.1665 4.5132 1.3473283871 PGP hypothetical protein LOC283871 4.08631974E-07 2.32819565E-06 2.0473 1.7064 3.0403 1.6845 2.0110 5.4160 2.93118314 BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 2.21247769E-12 7.97761619E-11 2.0473 0.8612 0.9811 1.3409 0.4085 0.8453 0.697991373 UAP1L1 UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 0.00020241312 0.000650455964 2.0473 0.5794 1.3693 1.5606 0.4380 1.2162 1.534623483 TGDS TDP-glucose 4,6-dehydratase 0.0001316385 0.000440369576 2.0462 2.0315 2.8409 2.4123 1.9725 2.4803 2.9959219738 C10orf35 chromosome 10 open reading frame 35 0.00025642435 0.000808801257 2.0437 0.6388 1.8559 1.0527 0.4438 1.3647 1.023751184 GPN3 GPN-loop GTPase 3 4.05865226E-07 2.31387501E-06 2.0434 2.3520 3.3141 2.0835 1.8482 3.9018 1.90054983 OPHN1 oligophrenin 1 0.00448020181 0.010675827796 2.0432 1.7238 0.6634 1.1285 1.4080 0.3324 1.0788408050 NOMO3 NODAL modulator 3 2.19141031E-09 2.29201197E-08 2.0430 1.5807 1.3031 1.6728 1.5079 1.7288 1.7386134637 ADAT2 deaminase domain containing 1 7.46424449E-05 0.000263600068 2.0429 1.4315 4.3010 1.0204 0.9261 1.7154 0.78509092 SART1 squamous cell carcinoma antigen recognized by T cells 3.95841676E-11 7.77722483E-10 2.0424 2.1499 1.9899 1.4229 2.1882 2.4867 2.353010488 CREB3 cAMP responsive element binding protein 3 2.26303346E-09 2.35613375E-08 2.0422 3.3463 2.1482 3.6855 1.5223 3.7624 2.34461163 CKS1B CDC28 protein kinase regulatory subunit 1B 1.52905558E-05 6.17161556E-05 2.0421 0.3321 0.3321 0.3321 0.3970 0.3970 0.397055199 FAM86C1 family with sequence similarity 86, member C1 0.00042009008 0.001261458587 2.0402 1.1263 3.4564 1.6158 0.9998 4.7894 2.424323076 RRP1B ribosomal RNA processing 1B 8.26578748E-10 9.97572449E-09 2.0400 20.8004 10.1232 1.3211 20.0460 18.1016 1.1542283820 NOMO2 NODAL modulator 2 1.3500952E-09 1.52277404E-08 2.0398 1.4173 2.3354 1.4401 1.1822 2.9402 1.9537222068 TMED4 transmembrane emp24 protein transport domain containing 4 5.03653528E-13 2.68301961E-11 2.0393 1.8947 3.7336 1.9608 1.5869 5.1750 2.14679466 IL27RA interleukin 27 receptor, alpha 1.35803712E-10 2.13362462E-09 2.0390 1.2246 1.2956 1.6299 1.2409 1.8771 2.161251239 ANKRD39 ankyrin repeat domain 39 2.72180298E-07 1.62260307E-06 2.0389 1.4203 2.1194 1.5212 1.0816 3.0123 1.6160162 AP1B1 adaptor-related protein complex 1, beta 1 subunit 1.15282215E-09 1.32772142E-08 2.0378 0.4868 0.9739 0.7468 0.3613 1.1769 0.7573

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1

81543 LRRC3 leucine rich repeat containing 3 0.02150354729 0.042031751819 2.0377 0.5515 0.9933 1.0176 0.0897 8.8274 0.7099729438 GATSL2 GATS protein-like 2 0.0126544002 0.026531405667 2.0367 0.3321 0.3321 0.3321 0.3970 0.3970 0.397051399 TRAPPC4 trafficking protein particle complex 4 3.94106693E-10 5.31447785E-09 2.0363 0.3321 0.3321 0.3321 0.3970 0.3970 0.397025 ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 7.03775998E-08 4.85254091E-07 2.0354 2.7426 2.3988 1.9107 1.9487 2.5792 2.06233991 LIPE lipase, hormone-sensitive 1.02732744E-08 8.73897908E-08 2.0353 0.2911 0.1883 0.2646 0.3740 0.2258 0.306910263 CDK2AP2 cyclin-dependent kinase 2 associated protein 2 1.64965088E-08 1.33373543E-07 2.0351 1.2246 2.4542 1.6024 0.9768 3.1105 2.378279720 VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 6.57179557E-06 2.87272365E-05 2.0343 1.7016 2.3794 1.5116 1.8513 2.5821 1.42138819 SAP30 Sin3A-associated protein, 30kDa 4.53359448E-05 0.000166642202 2.0341 2.7325 3.0470 1.9916 2.7493 4.3057 3.043856616 DIABLO diablo, IAP-binding mitochondrial protein 0.00069522797 0.001989850478 2.0340 0.6127 0.6732 1.1424 0.4438 0.3712 0.837884232 MAF1 MAF1 homolog (S. cerevisiae) 5.08732992E-11 9.53756288E-10 2.0339 1.4575 19.5587 12.6090 0.0472 8.8934 4.797679169 C1orf35 chromosome 1 open reading frame 35 3.92392196E-07 2.25040496E-06 2.0337 1.1492 2.4701 1.6742 1.0547 3.2791 2.4215160760 PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) 9.09025114E-06 3.85286636E-05 2.0334 2.1414 2.1491 2.0118 2.1835 3.4037 2.71553735 KARS lysyl-tRNA synthetase 1.26631429E-10 2.01757684E-09 2.0330 1.3716 1.2055 1.0386 1.5048 2.0089 1.59174292 MLH1 mutL homolog 1 1.97823019E-07 1.22280859E-06 2.0322 0.4105 0.8254 0.4408 0.3259 0.8067 0.34372820 GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 2.60373108E-09 2.66827674E-08 2.0321 1.2500 1.1102 0.9121 1.0002 1.2814 1.03496813 STXBP2 syntaxin binding protein 2 3.64287877E-07 2.10913367E-06 2.0317 0.4928 0.7548 0.6898 0.4463 1.4707 0.7319115650 TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.02109494652 0.041356959524 2.0316 0.9106 1.2297 1.1737 0.8687 1.0656 0.7664129804 FBLN7 fibulin 7 1.92377627E-07 1.19278046E-06 2.0314 1.1677 2.1550 1.7953 0.9223 1.2854 1.125656993 TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 2.28343048E-09 2.36926983E-08 2.0313 2.1004 1.5812 2.3869 2.4963 2.4476 2.600384514 GHDC GH3 domain containing 9.53546737E-10 1.1255301E-08 2.0310 1.5058 1.7906 1.7818 1.2321 1.5931 1.7590

9150 CTDP1 3.28576073E-09 3.26823191E-08 2.0301 1.2159 1.8823 1.9933 1.0204 2.2396 2.54235695 PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 7.46245641E-10 9.13090125E-09 2.0290 2.2067 1.8539 1.3392 1.9677 3.2760 1.484723160 WDR43 WD repeat domain 43 9.7551613E-08 6.47462068E-07 2.0288 1.0298 2.0276 1.7071 1.3591 4.6811 3.1419144717 FAM109A family with sequence similarity 109, member A 0.00047357719 0.001404740643 2.0287 0.8792 0.9392 0.9485 0.8047 0.6347 0.8714375 ARF1 ADP-ribosylation factor 1 4.31266355E-11 8.33872892E-10 2.0287 1.7758 2.3801 1.8298 1.8560 5.1598 2.9214401720 FIGNL2 fidgetin-like 2 0.0043362367 0.010370643576 2.0275 0.4801 0.8314 0.3452 0.2215 0.1873 0.25124094 MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.01101903563 0.023510020909 2.0275 2.8425 2.0906 2.4170 2.0370 1.3917 2.66666897 TARS threonyl-tRNA synthetase 1.46694055E-07 9.33609813E-07 2.0272 2.0853 2.5499 1.7946 2.0191 4.2081 2.464329967 LRP12 low density lipoprotein receptor-related protein 12 0.00248839644 0.006312787798 2.0268 1.0864 0.9164 0.7528 0.8004 1.2433 0.81821954 MEGF8 multiple EGF-like-domains 8 1.43109922E-08 1.17682471E-07 2.0266 0.8891 1.2479 1.2367 0.7167 1.6533 1.403455190 NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.01226387256 0.025813325587 2.0255 0.9765 1.4303 1.2688 0.7189 1.2989 2.00643843 IPO5 importin 5 6.16631541E-07 3.372371E-06 2.0232 0.6859 1.7671 0.6494 0.5631 2.1689 0.991160672 MIIP migration and invasion inhibitory protein 1.60079756E-07 1.01035485E-06 2.0228 1.1602 1.7028 1.5752 1.1529 3.6085 2.001627068 PPA2 pyrophosphatase (inorganic) 2 1.84126432E-10 2.76674191E-09 2.0225 1.9096 2.5715 1.1732 1.9919 4.4647 1.85328192 CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 3.05424356E-11 6.34172026E-10 2.0225 1.2254 0.8450 1.0872 1.2883 1.9144 2.452983931 STK40 serine/threonine kinase 40 1.37778877E-11 3.37014142E-10 2.0222 1.7655 1.9627 1.0547 1.3546 1.3079 1.486179613 TANGO6 transmembrane and coiled-coil domains 7 7.78757307E-12 2.15271611E-10 2.0220 1.9567 3.5707 1.8120 1.8997 5.4153 2.105585376 RIMBP3 RIMS binding protein 3 0.00041263323 0.001242142488 2.0219 0.6947 1.1087 0.7444 0.5982 0.5934 0.7521

8517 IKBKG 2.37613314E-09 2.45986996E-08 2.0218 0.9340 1.5619 1.7665 0.4141 1.1751 1.20712137 EXTL3 exostosin-like glycosyltransferase 3 6.35515183E-07 3.45702097E-06 2.0210 2.3152 4.0380 1.6448 2.1699 6.5338 1.9464923 CD6 CD6 molecule 8.7434408E-07 4.61201358E-06 2.0198 2.4481 3.6454 2.0214 2.5715 6.2259 2.1484

150221 RIMBP3C 0.00036121092 0.001100741475 2.0198 0.6862 1.2127 1.0375 0.4785 0.7063 0.8516152579 SCFD2 sec1 family domain containing 2 6.60823778E-07 3.58295907E-06 2.0190 2.6788 2.6846 1.9584 2.5739 4.0811 2.5608100272216 LOC100272216 uncharacterized LOC100272216 0.00252431235 0.006396371563 2.0180 0.0663 0.0982 0.1730 0.5276 0.3364 0.1613254359 ZDHHC24 zinc finger, DHHC-type containing 24 2.10886425E-08 1.66091239E-07 2.0174 1.6825 3.4142 1.5859 0.8246 1.6315 1.07965692 PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 1.36405858E-10 2.14124385E-09 2.0169 2.6276 1.9495 1.8972 2.8038 2.2832 2.3788112597 LINC00152 long intergenic non-protein coding RNA 152 6.17188574E-05 0.000221383385 2.0164 2.2699 2.4992 1.8186 1.9092 2.5439 1.4227326625 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.00017834203 0.000579215339 2.0157 0.6599 2.0803 2.5813 0.1632 0.5388 1.1679197259 MLKL mixed lineage kinase domain-like 1.88359964E-07 1.17065077E-06 2.0154 2.2667 3.6988 1.8817 1.6583 3.8049 2.227284964 ALKBH6 alkB, alkylation repair homolog 6 (E. coli) 1.30741322E-05 5.35508953E-05 2.0153 1.7031 2.8528 2.6013 1.5102 3.2398 2.4431

5250 SLC25A3 9.22861928E-11 1.55415052E-09 2.0149 2.2146 2.3744 2.1159 2.5074 4.2739 2.946010196 PRMT3 protein arginine methyltransferase 3 2.68131767E-06 1.27023688E-05 2.0145 2.8801 2.6856 1.9616 2.3206 4.8590 3.005554148 MRPL39 mitochondrial ribosomal protein L39 7.63967748E-07 4.08761894E-06 2.0144 2.5575 2.6024 1.9457 2.1869 4.6929 2.47873875 KRT18 keratin 18 2.35104503E-05 9.11678583E-05 2.0139 1.4390 0.8982 1.2180 0.7196 0.4156 0.91075700 PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 9.5668751E-11 1.5964013E-09 2.0138 1.3704 2.2460 0.9008 1.3941 1.9156 1.019723087 TRIM35 tripartite motif containing 35 1.24738264E-08 1.03789506E-07 2.0134 2.6913 2.1156 3.3469 1.8842 2.0706 2.85872022 ENG endoglin 0.00013605927 0.000453994695 2.0124 0.4597 0.8118 0.6389 0.3555 0.9262 0.471581605 URM1 ubiquitin related modifier 1 1.53250543E-10 2.37062502E-09 2.0122 2.7738 1.9697 2.1574 2.4534 2.9504 2.56652539 G6PD glucose-6-phosphate dehydrogenase 1.55425459E-08 1.26393022E-07 2.0121 0.7652 0.9722 3.3403 0.5295 0.8019 2.0214127002 ATXN7L2 ataxin 7-like 2 1.90312258E-05 7.53006838E-05 2.0115 0.7366 1.9490 1.8799 0.5641 2.1110 1.767911060 WWP2 WW domain containing E3 ubiquitin protein ligase 2 5.5545062E-13 2.91643498E-11 2.0113 0.7942 0.4999 0.6596 0.6591 0.6248 0.6331112812 FDX1L ferredoxin 1-like 2.11267108E-05 8.2856248E-05 2.0112 1.2874 2.1830 1.8112 1.0964 1.8837 1.862754472 TOLLIP toll interacting protein 3.26850678E-11 6.69530895E-10 2.0109 0.2184 1.1932 2.3419 0.4377 1.1458 4.756854867 TMEM214 transmembrane protein 214 1.60217955E-09 1.76037431E-08 2.0105 1.3990 1.6325 2.3380 1.4080 2.5075 2.875756954 NIT2 nitrilase family, member 2 1.08881372E-06 5.62954281E-06 2.0078 2.1868 1.6017 2.4956 1.5901 2.1759 2.49399871 SEC24D SEC24 family member D 2.22566772E-06 1.07415216E-05 2.0077 0.5574 0.5749 0.5417 0.7143 0.5905 0.808879133 NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 0.00063356467 0.001829118923 2.0075 1.6787 41.7653 1.1864 0.5007 10.7660 1.10349742 IFT140 intraflagellar transport 140 homolog (Chlamydomonas) 0.00011342508 0.00038522363 2.0073 0.7343 1.2525 1.0858 0.4622 1.0059 1.2500151174 LOC151174 uncharacterized LOC151174 0.00368404767 0.008962178013 2.0069 0.0660 0.2827 0.7120 0.0976 1.0380 0.4236

146712 B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 8.55193754E-05 0.000298606923 2.0063 0.5916 1.4710 1.2108 0.3816 0.7375 1.08388623 ASMTL acetylserotonin O-methyltransferase-like 2.22185305E-10 3.26085935E-09 2.0063 1.3426 0.9123 1.5743 1.1356 1.6658 2.207980233 C17orf70 chromosome 17 open reading frame 70 1.326442E-06 6.7382001E-06 2.0051 0.6899 0.9327 0.7195 0.6737 0.8902 1.319180331 DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 3.536854E-11 7.12518152E-10 2.0050 1.0842 1.1732 0.6500 0.9428 1.1466 0.604383856 FSD1L fibronectin type III and SPRY domain containing 1-like 0.00316495025 0.007826881929 2.0036 1.1619 1.8163 1.5876 0.9116 1.2795 1.616479177 ZNF576 zinc finger protein 576 8.19943937E-05 0.000287484973 2.0027 1.5962 2.9697 1.5344 1.0435 1.8949 1.19507409 VAV1 vav 1 guanine nucleotide exchange factor 8.243925E-11 1.40778502E-09 2.0021 0.9283 1.8331 0.9106 1.0200 2.4794 1.348879829 NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 2.92570646E-05 0.000111371893 2.0018 1.5633 1.2371 1.3442 1.0259 0.8136 0.99961719 DHFR dihydrofolate reductase 0.00232794478 0.005944131769 2.0004 2.0584 5.6533 2.1243 1.2131 5.7924 1.37481001 CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00209064248 0.005400087561 2.0004 0.8726 1.2336 0.8944 0.1853 0.6345 0.76914076 CAPRIN1 cell cycle associated protein 1 3.11063998E-10 4.37212414E-09 2.0001 2.1353 2.6013 1.3765 2.0284 6.0986 2.42614828 NMB neuromedin B 0.00195208265 0.005070863537 2.0000 1.2034 1.9531 1.3452 1.1275 1.4556 0.91344771 NF2 neurofibromin 2 (merlin) 2.79608765E-10 4.00706773E-09 1.9991 0.8039 0.7270 0.6350 0.8725 0.7455 1.001623191 CYFIP1 cytoplasmic FMR1 interacting protein 1 0.00054144764 0.001586741178 1.9983 0.6985 0.4960 0.5372 0.6378 0.4593 0.510927351 DESI1 desumoylating isopeptidase 1 9.97419429E-10 1.16676362E-08 1.9983 1.9996 2.6247 2.0963 1.5602 5.6314 2.27539647 PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 3.2833552E-09 3.26761799E-08 1.9970 1.1281 1.4098 1.3875 0.6331 0.9724 1.106910327 AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 6.55572751E-10 8.18771381E-09 1.9961 1.1282 1.7538 0.9163 1.0876 2.2766 1.21447919 DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.00135062638 0.003645294719 1.9956 0.4085 0.4955 0.4271 0.4449 0.5551 0.4774144608 C12orf60 chromosome 12 open reading frame 60 0.01698779397 0.034245473454 1.9954 3.4585 19.4152 1.7473 0.7274 7.2130 1.1574708 C1QBP complement component 1, q subcomponent binding protein 4.57369734E-07 2.57536511E-06 1.9925 2.4667 3.2851 1.9267 1.5952 4.2046 1.81765496 PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 2.9199052E-10 4.1504582E-09 1.9920 1.5665 2.9526 1.7099 1.3821 3.8594 2.11493071 NCKAP1L NCK-associated protein 1-like 6.28946932E-10 7.912775E-09 1.9919 2.6415 1.4580 1.6891 1.9586 1.3120 1.863180764 THAP7 THAP domain containing 7 5.29109364E-09 4.94268216E-08 1.9915 1.8801 5.7245 4.1175 1.4948 7.4026 3.381727238 GPKOW G patch domain and KOW motifs 2.46999332E-12 8.64592299E-11 1.9912 1.5096 2.2012 1.7186 1.7836 2.5059 1.62365718 PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 9.53015443E-09 8.18303485E-08 1.9899 2.3609 1.2846 1.7601 1.7628 1.9007 2.4381126133 ALDH16A1 aldehyde dehydrogenase 16 family, member A1 1.46612475E-07 9.33415732E-07 1.9896 2.2283 2.4334 1.8337 2.0473 3.2649 3.39581445 CSK c-src tyrosine kinase 1.69298166E-10 2.57570033E-09 1.9896 2.3509 1.5909 1.8642 2.3175 1.6883 1.635889941 RHOT2 ras homolog family member T2 2.83045989E-08 2.14650481E-07 1.9856 0.6016 0.6868 0.9531 0.4870 0.8628 1.151910243 GPHN gephyrin 1.65723382E-05 6.65515963E-05 1.9843 0.8488 2.5328 0.8922 0.8746 2.2477 1.340164789 EXO5 exonuclease 5 0.00017226905 0.000560987355 1.9842 1.6767 2.6038 1.8087 1.4774 3.9722 1.810856902 PNO1 partner of NOB1 homolog (S. cerevisiae) 2.04279731E-05 8.03227728E-05 1.9839 1.9438 3.8605 1.0255 1.2169 3.2961 1.03491465 CSRP1 cysteine and glycine-rich protein 1 3.47428147E-09 3.435177E-08 1.9838 0.5640 0.5531 0.8884 0.5496 0.4974 0.7383389119 FAM212A family with sequence similarity 212, member A 0.00850462974 0.018749589119 1.9829 1.0746 2.0536 1.0488 0.6952 2.1234 1.602111137 PWP1 PWP1 homolog (S. cerevisiae) 1.82467981E-09 1.96583429E-08 1.9829 2.0012 3.5736 1.8304 2.2996 4.4208 2.233554930 HAUS4 HAUS augmin-like complex, subunit 4 1.47156382E-07 9.35900247E-07 1.9818 0.2126 0.2859 0.7920 0.2564 0.2894 0.53271267 CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 2.75894082E-07 1.64259911E-06 1.9818 2.0171 2.1787 2.3258 1.5535 1.9867 2.225756623 INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 9.19010859E-07 4.81979518E-06 1.9810 1.1130 2.0219 1.1475 0.9601 3.9078 1.95516502 SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 6.59297261E-06 2.88129145E-05 1.9806 3.1439 4.0227 2.7835 7.0366 2.5395 2.5087100294362 LOC100294362 uncharacterized LOC100294362 0.0071393022 0.016062461751 1.9806 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702624 GATA2 GATA binding protein 2 0.00463081039 0.010997422327 1.9800 1.0869 1.2961 1.5020 0.5092 1.0258 1.129864423 INF2 inverted formin, FH2 and WH2 domain containing 3.96144943E-07 2.2673158E-06 1.9796 0.6574 1.4171 0.7325 0.5571 0.9242 1.12298365 HIST1H4H histone cluster 1, H4h 1.83224979E-05 7.28118054E-05 1.9793 3.5337 3.7029 1.4673 4.5121 4.3821 2.27938317 CDC7 cell division cycle 7 0.00044716724 0.001333328964 1.9793 0.9532 1.2240 1.0130 0.9857 1.3061 1.0649389523 GATSL1 GATS protein-like 1 0.02295836776 0.044447477818 1.9787 0.7886 0.9487 1.1917 0.5363 0.7100 0.8549114793 FMNL2 formin-like 2 0.00075790549 0.002157507553 1.9776 0.4313 1.8622 0.7941 0.5659 2.9098 0.69339684 LRRC14 leucine rich repeat containing 14 1.63431587E-09 1.78922826E-08 1.9775 0.4927 6.7952 4.8615 0.0237 1.0716 3.1457

506 ATP5B 3.11711289E-10 4.37449207E-09 1.9760 4.1074 2.3166 2.0854 3.3475 1.3014 1.82074751 NEK2 NIMA-related kinase 2 0.01303972239 0.027236146255 1.9759 0.8232 0.9406 0.8511 0.6684 0.5719 1.042810554 AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.57199824E-08 1.27773807E-07 1.9757 0.6071 0.7756 0.8099 0.5445 0.8095 0.66349373 PLAA phospholipase A2-activating protein 9.72558371E-10 1.14133504E-08 1.9753 3.1125 0.1256 1.5794 10.9865 0.1184 2.5981157922 CAMSAP1 calmodulin regulated spectrin-associated protein 1 2.18818351E-09 2.28994783E-08 1.9752 1.3648 1.6146 1.5795 0.7702 1.6876 1.493229960 FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli) 3.01913871E-09 3.04110819E-08 1.9750 0.3233 1.0786 0.8169 0.3815 0.8751 1.157927348 TOR1B torsin family 1, member B (torsin B) 2.53999467E-08 1.95167294E-07 1.9747 2.4944 3.8144 1.8772 3.1193 5.0040 2.490883990 BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.00078435877 0.002225089814 1.9726 0.9232 1.0524 0.9762 0.9365 1.3690 1.169255588 MED29 mediator complex subunit 29 2.68200758E-09 2.73774539E-08 1.9725 2.8668 2.7126 1.5917 0.4100 2.9678 1.1504124751 KRBA2 KRAB-A domain containing 2 0.00431312553 0.010319422517 1.9714 0.8593 1.1749 1.0856 0.6544 1.6049 0.9204283932 FBXL19-AS1 hypothetical protein LOC283932 0.0153561944 0.031378705443 1.9713 0.3321 0.3321 0.3321 0.3970 0.3970 0.39709146 HGS hepatocyte growth factor-regulated tyrosine kinase substrate 3.7324391E-11 7.42101494E-10 1.9707 0.3189 2.3731 0.7778 0.3977 0.2810 0.171681577 GFOD2 glucose-fructose oxidoreductase domain containing 2 1.25214058E-07 8.09307136E-07 1.9697 2.5278 3.2089 2.7066 2.0092 3.2347 2.621556413 LTB4R2 leukotriene B4 receptor 2 0.00522107902 0.012219745855 1.9696 0.6154 0.8246 1.4837 0.3894 0.6266 0.698525855 BRMS1 breast cancer metastasis suppressor 1 1.19318583E-11 2.98181911E-10 1.9678 0.9384 0.9215 1.0732 0.6887 1.5864 1.0526

509 ATP5C1 2.94365739E-08 2.21800032E-07 1.9675 3.2243 30.9073 7.1933 0.4737 24.9785 5.808864375 IKZF4 IKAROS family zinc finger 4 (Eos) 0.00011055047 0.00037644021 1.9669 0.5757 0.6994 0.9314 0.4755 0.6123 0.7009

55041 PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 3.83655336E-09 3.75275712E-08 1.9664 1.0562 1.4524 1.0486 1.0549 1.2587 1.010984418 CYSTM1 chromosome 5 open reading frame 32 1.01195893E-07 6.68976611E-07 1.9654 0.9064 1.1509 1.3564 0.8663 1.2010 1.69197915 ALDH5A1 aldehyde dehydrogenase 5 family, member A1 2.15822711E-05 8.44616102E-05 1.9654 2.3067 2.7465 1.9269 1.5963 3.2693 1.8556

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

similar to Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1)

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3

ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

201725 C4orf46 hypothetical protein LOC201725 9.2067055E-05 0.00031848717 1.9653 4.8621 1.3257 2.3353 1.9104 0.9604 1.5024100507034 PITRM1-AS1 PITRM1 antisense RNA 1 0.00712218429 0.016036058007 1.9632 0.0815 0.0219 0.0886 0.2625 0.0173 0.0714

3177 SLC29A2 0.0006753328 0.00193654753 1.9622 1.1204 2.5377 1.7088 0.8316 2.6496 1.865923423 TMED3 transmembrane emp24 protein transport domain containing 3 2.2059472E-08 1.72917492E-07 1.9609 1.5210 2.6938 2.2461 1.1769 2.7574 2.05799158 FIBP fibroblast growth factor (acidic) intracellular binding protein 7.75527503E-12 2.14703614E-10 1.9607 2.2979 2.3354 2.7551 2.1216 3.0945 2.809180218 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 1.23344358E-08 1.02770091E-07 1.9603 1.8932 2.2505 0.9302 1.4489 2.9611 1.263181614 NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 3.92849027E-09 3.83038283E-08 1.9601 2.1548 1.9963 1.8763 2.3806 3.7740 2.87742010 EMD emerin 5.00577852E-09 4.71715241E-08 1.9586 0.8275 3.1047 2.1131 0.9708 3.9050 3.0775400569 MED11 mediator complex subunit 11 1.41708977E-05 5.76041474E-05 1.9585 1.6227 2.0391 2.1369 2.0169 2.7085 2.476284154 RPF2 ribosome production factor 2 homolog (S. cerevisiae) 0.00064864624 0.001867349003 1.9585 3.7852 2.1469 1.8528 3.5391 3.2401 2.7385

6598 SMARCB1 4.27106998E-10 5.67983921E-09 1.9577 1.3426 0.7750 1.5174 0.9133 0.7310 1.49942650 GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.00817078022 0.018118506812 1.9572 0.4697 0.3775 0.8908 0.5846 0.3858 0.774190120 C9orf69 hypothetical gene supported by AK023162 5.1961744E-12 1.58505006E-10 1.9569 1.3066 2.8329 2.2225 0.9769 4.5923 3.1511283373 ANKRD52 ankyrin repeat domain 52 4.53684869E-08 3.27657309E-07 1.9569 1.8308 1.8586 1.3223 1.4267 3.0239 1.5279

4719 NDUFS1 6.94114079E-09 6.22013362E-08 1.9563 1.9397 2.4920 2.3623 1.0702 2.0312 2.263454890 ALKBH5 alkB, alkylation repair homolog 5 (E. coli) 1.78227194E-09 1.92582336E-08 1.9550 1.5686 2.8970 1.4140 1.9667 3.9394 2.779611344 TWF2 twinfilin actin-binding protein 2 2.26986407E-09 2.36055528E-08 1.9545 2.1436 3.1797 2.2232 2.0067 3.9106 2.853125853 DCAF12 DDB1 and CUL4 associated factor 12 1.48506325E-09 1.64554735E-08 1.9544 1.3795 2.1328 2.2827 1.5363 3.6634 3.27753185 HNRNPF heterogeneous nuclear ribonucleoprotein F 3.78650435E-10 5.15167591E-09 1.9535 2.1254 2.9685 1.7981 1.8943 3.7512 2.767525912 C1orf43 chromosome 1 open reading frame 43 5.75440463E-10 7.33225114E-09 1.9531 0.3321 0.3321 0.3321 0.3970 0.3970 0.397081889 FAHD1 fumarylacetoacetate hydrolase domain containing 1 2.21579926E-05 8.6492382E-05 1.9526 1.9341 1.1813 0.4465 1.1434 2.0870 0.414981873 ARPC5L actin related protein 2/3 complex, subunit 5-like 1.08745595E-09 1.25839108E-08 1.9522 1.7191 1.1752 1.5881 1.4050 2.0558 3.756523646 PLD3 phospholipase D family, member 3 4.25857252E-05 0.00015738802 1.9521 0.2843 0.4171 0.3578 0.2630 0.3385 0.414279603 CERS4 LAG1 homolog, ceramide synthase 4 (S. cerevisiae) 5.12533797E-07 2.84997491E-06 1.9499 1.3380 1.0742 2.7138 0.8813 1.1910 3.496384687 PPP1R9B protein phosphatase 1, regulatory subunit 9B 7.7152301E-10 9.39817896E-09 1.9487 2.0859 3.0133 1.2610 2.0573 4.9132 3.167479814 AGMAT agmatine ureohydrolase (agmatinase) 3.19169986E-06 1.48734353E-05 1.9486 2.1170 2.2600 2.2979 1.7805 2.2697 2.206657622 LRFN1 leucine rich repeat and fibronectin type III domain containing 1 1.06768687E-05 4.45609286E-05 1.9469 0.1379 0.0504 0.0989 0.1661 0.0577 0.20952671 GFER growth factor, augmenter of liver regeneration 8.01969191E-11 1.37721626E-09 1.9466 1.7060 1.5147 1.6618 0.9010 1.3552 1.68548498 RANBP3 RAN binding protein 3 1.21681145E-11 3.02693586E-10 1.9466 1.9815 6.8924 1.3138 1.1958 9.9180 1.12678372 HYAL3 hyaluronoglucosaminidase 3 0.00091739486 0.002570956877 1.9456 0.3321 0.3321 0.3321 0.3970 0.3970 0.39705025 P2RX4 purinergic receptor P2X, ligand-gated ion channel, 4 4.71066333E-06 2.12159824E-05 1.9455 1.3932 0.8236 1.6712 1.1212 0.8751 1.9375481 ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.00216765352 0.005575361068 1.9452 2.0093 3.7306 1.7874 1.5023 4.9657 2.3825154761 LOC154761 family with sequence similarity 115, member C pseudogene 4.16347702E-09 4.02726586E-08 1.9439 1.8822 2.2644 1.9130 2.1670 4.5795 2.6952387338 NSUN4 NOP2/Sun domain family, member 4 1.68998381E-08 1.36042921E-07 1.9438 1.0206 1.2631 1.6973 1.2831 1.3908 1.8220

84259 DCUN1D5 1.2011968E-07 7.79966879E-07 1.9436 2.1247 1.8779 1.5998 2.0369 2.6773 2.0638164656 TMPRSS6 transmembrane protease, serine 6 0.01314188183 0.027415054771 1.9434 0.0174 0.0467 0.2987 0.0226 0.0629 0.2470197320 ZNF778 zinc finger protein 778 0.00051889597 0.001528004383 1.9433 0.8974 1.7989 0.9794 0.7538 1.4629 1.31729527 GOSR1 golgi SNAP receptor complex member 1 1.72789349E-10 2.62008879E-09 1.9425 2.3459 1.6727 2.2394 2.1236 1.7068 2.546357823 SLAMF7 SLAM family member 7 0.02462688295 0.047262094862 1.9411 0.3956 0.6370 1.2586 0.3684 0.7894 0.724755760 DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 7.12686689E-06 3.09022572E-05 1.9399 0.1237 0.9794 0.1436 0.1778 0.5257 0.31367692 ZNF133 zinc finger protein 133 0.00064485595 0.00185760806 1.9396 1.1845 1.2902 1.1610 1.3438 1.8375 1.768410134 BCAP31 B-cell receptor-associated protein 31 1.17303396E-08 9.8328517E-08 1.9396 3.7379 2.7839 2.2891 3.2370 5.7602 3.7598171568 POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) 6.22111978E-07 3.39929129E-06 1.9391 1.6800 2.3903 1.3337 1.4651 2.5212 1.5510440288 UBL7-AS1 UBL7 antisense RNA 1 (head to head) 0.00117304878 0.003213003651 1.9390 1.5125 14.7192 3.2154 0.5197 3.4259 1.12876626 SNRPA small nuclear ribonucleoprotein polypeptide A 4.01375356E-07 2.2911373E-06 1.9386 7.7289 4.1660 1.4933 8.9485 9.5407 2.5578339263 C17orf51 chromosome 17 open reading frame 51 0.0025325267 0.00641451732 1.9384 1.6810 1.5920 0.9917 1.6181 1.8632 1.179523310 NCAPD3 non-SMC condensin II complex, subunit D3 1.25150466E-05 5.14917656E-05 1.9382 3.9623 2.8591 1.4420 3.1388 6.1715 1.51178776 MTMR1 myotubularin related protein 1 1.45454771E-08 1.19248271E-07 1.9376 1.5648 1.2584 1.2677 1.3420 1.1364 1.27923704 ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 6.47217072E-11 1.1594069E-09 1.9373 2.2369 3.0882 2.0679 1.9087 3.6117 2.390384626 KRBA1 KRAB-A domain containing 1 4.14968816E-06 1.88708567E-05 1.9371 0.3945 0.6910 0.8350 0.4545 0.6378 0.760889970 RSPRY1 ring finger and SPRY domain containing 1 1.77918674E-06 8.80056853E-06 1.9369 5.7138 2.7882 2.9123 3.9420 3.0530 2.558565996 MGC2752 hypothetical protein MGC2752 8.69010111E-10 1.03713604E-08 1.9365 2.1401 2.0638 2.0147 1.3154 1.8356 2.4694645455 CEP170P1 centrosomal protein 170kDa-like 0.0014350788 0.003851044183 1.9364 0.0762 0.0231 0.1086 0.2193 0.0136 0.2228997 CDC34 cell division cycle 34 1.33607235E-09 1.50975349E-08 1.9363 1.0096 1.8833 1.4018 0.8503 2.6494 2.573656647 BCCIP BRCA2 and CDKN1A interacting protein 6.85850987E-09 6.1691451E-08 1.9360 4.0483 7.7612 1.8640 2.7653 7.1955 1.30359100 USP10 ubiquitin specific peptidase 10 6.30237708E-11 1.13455206E-09 1.9348 1.4615 1.4583 1.6854 1.4377 2.7843 2.27563005 H1F0 H1 histone family, member 0 0.00822206815 0.018210136887 1.9347 1.1375 1.9531 2.1344 0.7376 1.2566 2.05251871 E2F3 E2F transcription factor 4, p107/p130-binding 7.49151717E-08 5.12677909E-07 1.9342 2.4414 2.7423 1.8879 1.7228 2.6423 2.362451027 BOLA1 bolA family member 1 2.6882459E-05 0.000103062587 1.9335 0.9017 0.7348 0.9935 0.8303 0.8538 1.4486151888 BTLA B and T lymphocyte associated 5.1195311E-05 0.000186342773 1.9329 1.7725 2.0305 1.6772 1.9345 1.9009 1.6464203062 TSNARE1 t-SNARE domain containing 1 1.1338167E-05 4.70308712E-05 1.9322 1.0852 1.2635 0.9942 0.8969 1.3405 1.1273

4245 MGAT1 2.08424869E-06 1.01312562E-05 1.9317 1.8744 1.7400 2.0699 1.6288 1.5204 2.097279033 ERI3 ERI1 exoribonuclease family member 3 2.09105315E-07 1.28558961E-06 1.9304 0.8830 0.8686 1.1120 0.7197 0.5569 0.694557679 ALS2 amyotrophic lateral sclerosis 2 (juvenile) 5.41849301E-05 0.000196441873 1.9302 1.6013 1.6386 1.0151 1.7632 1.7777 1.254984878 ZBTB45 zinc finger and BTB domain containing 45 1.90177527E-07 1.18074202E-06 1.9295 1.7409 2.2027 2.2856 1.3783 2.5694 2.65298165 AKAP1 A kinase (PRKA) anchor protein 1 4.12707154E-08 3.01518797E-07 1.9289 1.0529 1.1715 1.3533 0.8536 1.0149 1.8995113402 SFT2D1 SFT2 domain containing 1 3.98591295E-07 2.2780976E-06 1.9283 1.7842 1.6438 1.4489 1.6087 1.3216 1.11295558 PRIM2 primase, DNA, polypeptide 2 (58kDa) 1.43146414E-05 5.81367255E-05 1.9283 2.6348 2.1879 3.1536 2.4967 2.5208 3.3417284018 C17orf58 chromosome 17 open reading frame 58 0.00205833323 0.00532566763 1.9279 1.4699 1.4464 1.4600 0.9955 2.3722 1.94865916 RARG retinoic acid receptor, gamma 3.13584383E-06 1.46505084E-05 1.9271 1.6289 2.4129 2.0795 1.6594 2.3312 2.159992906 HNRNPLL heterogeneous nuclear ribonucleoprotein L-like 1.12966776E-08 9.52528351E-08 1.9267 0.7652 1.6515 0.8869 0.9465 2.0595 1.4888170685 NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 0.00324297955 0.007996723668 1.9260 1.7999 3.0811 1.2401 1.3274 3.0585 1.54005595 MAPK3 mitogen-activated protein kinase 3 2.20396063E-09 2.30250249E-08 1.9257 1.3216 1.7575 1.7551 1.5338 1.8787 1.933225793 FBXO7 F-box protein 7 6.13466212E-12 1.79348074E-10 1.9254 1.5427 1.4013 0.9977 1.3546 1.6279 1.367285002 FAM86B1 family with sequence similarity 86, member B1 0.00359351843 0.008761778598 1.9253 0.7617 0.8527 1.2036 0.8194 1.1786 1.476379676 OGFOD2 2-oxoglutarate and iron-dependent oxygenase domaincontaining 2 1.76134157E-08 1.4127846E-07 1.9253 0.9168 1.3919 1.8258 0.3083 0.4388 1.190854963 UCKL1 uridine-cytidine kinase 1-like 1 6.32838685E-09 5.74998929E-08 1.9252 1.0652 1.4461 1.0253 0.8495 1.6081 1.42024924 NUCB1 nucleobindin 1 1.3533474E-09 1.52550054E-08 1.9238 0.8414 1.6281 1.3072 0.8798 1.6004 1.756993517 SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 0.00106889772 0.002949841286 1.9235 2.0828 1.3712 1.4603 1.6956 1.0181 1.472053354 PANK1 pantothenate kinase 1 0.00147159304 0.003940349938 1.9233 1.7403 1.7785 1.3597 1.4620 1.3220 1.269254903 MKS1 Meckel syndrome, type 1 0.00022836483 0.000725810093 1.9231 2.1028 0.9048 1.4797 1.9732 1.0556 1.53243663 IRF5 interferon regulatory factor 5 0.00560382097 0.012987445055 1.9226 0.6974 0.8431 0.9611 0.3637 0.6466 0.8653

9351 SLC9A3R2 0.0059713197 0.013740797744 1.9224 0.4194 0.9713 0.6538 0.1967 0.4768 0.52445631 PRPS1 phosphoribosyl pyrophosphate synthetase 1 2.54302582E-08 1.95318066E-07 1.9216 2.0238 2.1150 1.0650 2.3931 3.6349 1.4611150223 YDJC LOC150223 protein 8.28226402E-10 9.98901176E-09 1.9214 0.8306 2.5585 1.3952 0.7356 4.5862 2.512323788 MTCH2 mitochondrial carrier 2 4.89214375E-07 2.73361623E-06 1.9211 1.5364 3.1026 1.8733 1.3814 3.8196 2.4533124995 MRPL10 mitochondrial ribosomal protein L10 4.52878278E-08 3.27204108E-07 1.9200 3.8742 0.4811 1.8883 9.1048 0.0568 0.500979980 DSN1 DSN1, MIS12 kinetochore complex component 0.00012747174 0.000428391331 1.9199 1.7090 2.1311 2.0694 1.9066 2.5583 2.58504779 NFE2L1 nuclear factor, erythroid 2-like 1 2.20954111E-07 1.34710494E-06 1.9199 1.3981 1.9520 1.7910 1.1367 2.2227 2.010310906 TRAFD1 TRAF-type zinc finger domain containing 1 8.26014346E-06 3.5329902E-05 1.9196 1.7354 1.5583 1.3392 1.7157 2.4711 1.82465929 RBBP5 retinoblastoma binding protein 5 1.26247915E-09 1.43995125E-08 1.9192 1.8223 1.4801 1.2479 1.6514 1.5382 1.2937220134 SKA1 chromosome 18 open reading frame 24 0.00716368238 0.016104183621 1.9191 1.4329 2.3390 1.6263 1.0876 2.4719 1.50936240 RRM1 ribonucleotide reductase M1 5.70715199E-07 3.14099642E-06 1.9184 1.0953 1.2010 1.0825 1.0485 1.6627 1.288051629 SLC25A39 solute carrier family 25, member 39 1.96839735E-08 1.5624047E-07 1.9178 1.3577 2.1584 1.7157 1.3241 2.3319 2.912555693 KDM4D lysine (K)-specific demethylase 4D 0.01455923201 0.02996803958 1.9177 0.3351 0.0761 0.6854 0.3929 0.4103 0.79537726 TRIM26 tripartite motif containing 26 6.13262105E-11 1.1138693E-09 1.9176 0.4828 0.5955 0.4729 0.5372 0.7578 0.5834873 CBR1 carbonyl reductase 1 1.66553529E-10 2.54241109E-09 1.9168 1.6412 1.6970 1.4246 1.4231 1.5451 1.25437106 TSPAN4 tetraspanin 4 0.01020315661 0.022003077734 1.9160 0.5037 1.6694 0.8731 0.3956 0.9463 0.6520

84912 SLC35B4 5.76796823E-09 5.31211268E-08 1.9150 1.4629 1.3056 1.5744 1.3725 1.5319 1.50665931 RBBP7 retinoblastoma binding protein 7 7.99825101E-10 9.67841341E-09 1.9148 1.2183 0.9128 1.3299 1.0596 0.8556 1.38045008 OSM oncostatin M 0.0139062173 0.028795829835 1.9144 2.2461 2.0366 2.5061 1.9087 3.2845 3.9632116349 C5orf55 hypothetical protein BC014011 0.00105020734 0.002903084505 1.9139 3.2162 4.9168 1.2629 0.4075 1.4720 1.25128356 HIST1H3J histone cluster 1, H3j 0.00931533808 0.020328419618 1.9127 1.4365 1.4650 2.0611 1.4057 1.0314 1.12922768 GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.58716149E-08 1.28941681E-07 1.9121 1.1487 1.1591 1.1205 0.7727 0.8761 0.944457180 ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 0.00040187152 0.001213718421 1.9117 2.2164 2.1293 1.6301 1.9480 2.6691 2.13085360 PLTP phospholipid transfer protein 0.00332836464 0.008178574323 1.9112 0.9914 1.4762 1.6950 0.6133 1.3788 1.175025862 USP49 ubiquitin specific peptidase 49 0.00123524452 0.003364697048 1.9072 1.9505 1.9644 2.3437 1.5155 2.3446 2.50953417 IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.00024329261 0.000770424647 1.9068 0.7854 0.8739 1.2343 0.5752 0.7210 0.57814817 NIT1 nitrilase 1 3.07962634E-07 1.81285221E-06 1.9060 3.4715 0.2573 1.5263 0.3453 0.5277 0.6175728402 TPI1P3 triosephosphate isomerase 1 pseudogene 3 0.00033881838 0.001040136 1.9059 0.1418 0.0691 0.1662 0.4681 0.0315 0.14331894 ECT2 ectodysplasin A 0.00127929744 0.003473818211 1.9058 0.6401 1.4039 0.9788 0.5124 1.4567 1.151710712 FAM189B family with sequence similarity 189, member B 1.87887885E-07 1.16811413E-06 1.9048 0.8248 0.8584 0.8814 0.7083 0.9836 0.920965993 MRPS34 mitochondrial ribosomal protein S34 7.35706055E-10 9.00993367E-09 1.9041 0.3321 0.3321 0.3321 0.3970 0.3970 0.397064689 GORASP1 golgi reassembly stacking protein 1, 65kDa 1.97543339E-07 1.22190653E-06 1.9036 1.1108 3.4891 1.9026 0.3173 1.9212 0.75365810 RAD1 RAD1 homolog (S. pombe) 3.31590062E-08 2.46694365E-07 1.9032 1.1696 15.6348 0.7447 0.6589 6.4939 0.84212593 GAMT guanidinoacetate N-methyltransferase 5.17537314E-08 3.68057436E-07 1.9028 0.8901 0.9162 2.0233 0.4435 0.7621 2.048611180 WDR6 WD repeat domain 6 9.99542491E-09 8.52644276E-08 1.9028 1.4525 2.5693 1.4060 1.5227 2.1575 1.892028227 PPP2R3B protein phosphatase 2, regulatory subunit B'', beta 8.40243192E-06 3.58629376E-05 1.9019 0.9910 1.9150 0.8856 2.2995 2.2313 1.23353656 IRAK2 interleukin-1 receptor-associated kinase 2 8.97681344E-05 0.000311714814 1.9015 1.7280 2.4302 1.2724 1.4197 2.2470 1.6806114112 TXNRD3 thioredoxin reductase 3 0.00134790507 0.003639562808 1.9014 1.2980 1.9916 1.6188 1.1590 2.4791 1.43078893 EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 4.20216273E-12 1.33766407E-10 1.9007 2.7839 2.0869 1.9714 2.7813 3.6803 3.15189320 TRIP12 thyroid hormone receptor interactor 12 8.53023455E-10 1.02273258E-08 1.9006 1.6605 1.4142 0.8742 1.5848 1.6815 1.378858493 INIP INTS3 and NABP interacting protein 0.00012341253 0.000415973754 1.9002 2.5516 1.6880 1.4315 2.1886 1.8237 1.72164350 MPG N-methylpurine-DNA glycosylase 1.98547563E-11 4.52561066E-10 1.8993 1.5806 2.7868 2.3774 0.8949 3.4633 3.01147204 TRIO trio Rho guanine nucleotide exchange factor 0.01043583546 0.022438642685 1.8989 0.7181 0.9951 0.9059 0.7531 1.3078 1.17644882 NPR2 natriuretic peptide receptor 2 0.00600121311 0.013796447649 1.8971 0.0381 0.0411 0.2451 0.1208 0.0495 0.16989854 C2CD2L C2CD2-like 4.55720354E-08 3.2886739E-07 1.8968 2.1588 2.6907 2.0597 2.3978 4.0383 2.326126580 BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.00581828124 0.013421491574 1.8968 2.2679 3.4405 1.9830 1.8067 4.4384 1.925291445 RNF185 ring finger protein 185 8.08003194E-12 2.21346842E-10 1.8966 8.8054 0.3144 2.4019 2.1944 2.4886 1.23564864 NPC1 Niemann-Pick disease, type C1 4.50459213E-05 0.000165843053 1.8965 0.6087 0.8659 0.7615 0.6857 1.2352 0.906610613 ERLIN1 ER lipid raft associated 1 6.08680555E-06 2.67389201E-05 1.8961 2.3424 1.9627 2.6782 2.5439 3.5682 3.28629070 ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 5.91821731E-09 5.42859773E-08 1.8960 2.1215 1.8355 1.6509 1.8848 2.6941 2.43639695 EDEM1 ER degradation enhancer, mannosidase alpha-like 1 4.77506301E-08 3.4242524E-07 1.8959 2.0218 1.6822 1.8020 2.0936 2.3725 3.01513661 IRF3 interferon regulatory factor 3 3.10893788E-10 4.37212414E-09 1.8949 3.1487 2.0665 2.4518 1.6362 1.7204 2.170151608 GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 7.6462713E-11 1.32303664E-09 1.8942 0.4555 1.0006 0.6837 0.5554 1.7088 1.09768504 PEX3 peroxisomal biogenesis factor 3 2.12160722E-06 1.02909496E-05 1.8941 6.0819 16.9670 0.9123 2.5697 11.3603 1.389457555 NLGN2 neuroligin 2 0.00078474917 0.002225851725 1.8941 0.6107 0.4134 0.7868 0.4086 0.3146 0.8156

solute carrier family 29 (equilibrative nucleoside transporter), member 2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)

mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2

solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4

55721 IQCC IQ motif containing C 0.00142381611 0.00382250485 1.8901 1.1635 1.6519 1.9029 0.9492 1.4782 1.8696133522 PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 3.95124611E-05 0.000147281046 1.8895 0.5966 0.7014 0.7850 0.6689 0.9197 1.103379729 SH3D21 SH3 domain containing 21 0.00248403932 0.00630457508 1.8895 0.5262 0.8207 0.9682 0.4512 0.6948 0.939084310 C7orf50 hypothetical protein MGC11257 1.72268789E-05 6.88472292E-05 1.8894 1.4002 1.8717 1.8948 1.1017 1.6632 1.8642

6602 SMARCD1 4.2820015E-09 4.12227247E-08 1.8893 2.2170 1.3459 1.8486 1.6221 1.3621 1.908510067 SCAMP3 secretory carrier membrane protein 3 3.37111747E-10 4.67352492E-09 1.8892 1.6106 2.0580 1.6311 1.5407 2.5468 1.8955527 ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 2.65079022E-06 1.25740495E-05 1.8869 0.6316 2.4715 1.4288 0.5828 2.7419 1.66987385 UQCRC2 ubiquinol-cytochrome c reductase core protein II 1.01152463E-09 1.18175052E-08 1.8863 1.4073 1.4286 0.9443 1.8523 3.3652 1.48225894 RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 1.6224788E-10 2.48916311E-09 1.8851 1.2428 1.7818 0.8101 1.6013 2.1653 1.651123165 NUP205 nucleoporin 205kDa 2.20640806E-07 1.34609309E-06 1.8845 2.5419 1.6792 1.5132 2.7590 2.3423 2.29239898 UBAP2L ubiquitin associated protein 2-like 5.28613753E-08 3.749546E-07 1.8844 1.1093 1.1782 0.8745 0.8075 1.0198 0.64675591 PRKDC protein kinase, DNA-activated, catalytic polypeptide 6.15679688E-07 3.36876E-06 1.8840 4.0987 4.6167 0.5865 0.4378 3.0566 0.16385691 PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 2.50061833E-09 2.57270822E-08 1.8833 2.1634 3.9591 1.9407 2.6884 5.5249 3.18524814 NINJ1 ninjurin 1 2.87801978E-06 1.3549904E-05 1.8828 1.6973 1.6478 1.6912 1.4693 2.3446 1.99403251 HPRT1 hypoxanthine phosphoribosyltransferase 1 8.25217161E-07 4.37815562E-06 1.8814 2.8516 2.0152 2.0042 2.2225 1.9446 2.14319650 MTFR1 mitochondrial fission regulator 1 0.00027015337 0.000848005909 1.8813 1.0532 1.3873 1.0488 0.8785 1.4856 1.213055095 SAMD4B sterile alpha motif domain containing 4B 2.67554998E-09 2.73268022E-08 1.8811 1.8355 1.7289 1.7312 2.5927 3.0587 2.859910483 SEC23B Sec23 homolog B (S. cerevisiae) 1.28113957E-07 8.25713661E-07 1.8810 2.7368 1.9006 2.0540 2.4054 2.5343 2.363322897 CEP164 centrosomal protein 164kDa 6.60559733E-09 5.98104432E-08 1.8809 0.3787 0.4856 0.4651 0.4656 0.5207 0.54067752 ZNF200 zinc finger protein 200 0.00017061853 0.00055660451 1.8806 1.2534 1.5004 0.9494 1.5984 2.3568 1.906879731 NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 9.78406756E-07 5.10055585E-06 1.8805 2.9096 2.4327 1.7402 2.6821 3.0998 2.264529028 ATAD2 ATPase family, AAA domain containing 2 1.72596734E-05 6.89481314E-05 1.8804 1.3370 1.6511 1.0756 1.1945 1.7640 1.609264601 VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 2.29370113E-11 5.04981707E-10 1.8802 0.1991 0.1754 0.3436 0.2568 0.2539 0.32124507 MTAP methylthioadenosine phosphorylase 9.94950706E-07 5.18236582E-06 1.8802 1.4467 1.3734 1.2250 1.4841 1.9837 1.40704430 MYO1B myosin IB 0.01104571573 0.023555942779 1.8800 0.2538 0.5560 0.4390 0.4116 0.3916 0.53145984 RFC4 replication factor C (activator 1) 4, 37kDa 8.85400607E-06 3.76233486E-05 1.8799 1.4374 3.6040 2.0764 1.5354 5.1169 2.58378738 CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.00053312385 0.001566115605 1.8795 2.3745 1.9801 1.9931 2.1729 1.8975 1.8504

55290 BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 8.92463811E-07 4.69539267E-06 1.8794 1.4870 1.9560 2.2605 1.4592 3.0268 2.551451495 PTPLAD1 protein tyrosine phosphatase-like A domain containing 1 1.13601992E-07 7.42394709E-07 1.8777 1.7632 1.7824 1.8432 1.5352 1.9124 2.017957696 DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 7.21929092E-08 4.96148013E-07 1.8757 0.6594 1.0808 0.8450 0.6572 2.0321 1.1389200205 IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) 2.99996866E-05 0.0001139377 1.8734 1.2643 0.7916 0.9438 1.0575 0.6180 0.9965728568 C12orf73 keratin, hair, basic, 5 0.00021625979 0.000690821476 1.8733 2.2907 3.1718 1.5871 1.4478 6.0033 1.7760

55344 PLCXD1 2.99369359E-07 1.76739157E-06 1.8721 1.2100 1.9561 1.6744 0.8300 1.6102 1.80167709 ZBTB17 zinc finger and BTB domain containing 17 3.09336037E-09 3.10048714E-08 1.8721 1.7426 3.7497 1.9168 1.3248 3.4094 1.682284918 LRP11 low density lipoprotein receptor-related protein 11 0.02022376968 0.039837076278 1.8717 0.8496 4.8015 1.1608 0.5481 2.2847 1.06584686 NCBP1 nuclear cap binding protein subunit 1, 80kDa 2.29850114E-08 1.79020515E-07 1.8714 2.3874 3.1176 2.7091 1.2752 2.9929 2.143257645 POGK pogo transposable element with KRAB domain 2.27109334E-11 5.03609436E-10 1.8714 2.2275 2.4371 1.9864 1.5585 1.8259 2.157060558 GUF1 GUF1 GTPase homolog (S. cerevisiae) 5.01548579E-08 3.57980298E-07 1.8713 1.4072 1.2236 1.2103 1.6645 1.3492 1.6204467 ATF3 activating transcription factor 3 0.01775494967 0.035607211277 1.8712 0.4880 1.6775 1.0498 0.5002 1.6785 1.178810054 UBA2 ubiquitin-like modifier activating enzyme 2 8.07263256E-09 7.05756661E-08 1.8708 2.3198 1.9591 1.6279 1.9889 2.4156 2.02809189 ZBED1 zinc finger, BED-type containing 1 1.05163012E-08 8.92493524E-08 1.8705 1.8392 2.9477 1.8997 1.6694 1.4200 1.1170142940 TRUB1 TruB pseudouridine (psi) synthase family member 1 2.09151349E-05 8.20969592E-05 1.8704 1.4587 1.0546 1.4715 1.3602 1.3950 2.0076285598 ARL10 ADP-ribosylation factor-like 10 0.00140567125 0.003779344474 1.8699 1.4859 1.9688 2.0587 1.1577 2.7191 2.26956996 TDG thymine-DNA glycosylase 2.7084078E-08 2.06630594E-07 1.8695 6.8486 4.3661 1.4399 2.6491 3.5355 0.4903430 ASCL2 achaete-scute family bHLH transcription factor 2 0.02190238513 0.042674384842 1.8691 0.6682 2.2347 1.2137 0.6281 0.5809 1.146310641 NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 2.58396775E-09 2.64950947E-08 1.8689 0.7263 0.5899 1.3894 0.3632 0.3070 0.94034242 MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.51510455E-09 2.5861559E-08 1.8687 1.5813 2.6087 1.8348 1.6920 2.9515 2.522554978 SLC35F6 solute carrier family 35, member F6 1.00730675E-06 5.24224121E-06 1.8686 1.9829 2.6628 2.3325 2.0129 3.1182 1.96943430 IFI35 interferon-induced protein 35 0.00626355905 0.014325666659 1.8683 1.9458 2.0059 1.8163 1.4555 2.5253 1.5313220359 TIGD3 tigger transposable element derived 3 0.00880191926 0.019321079847 1.8679 0.7459 2.6117 1.7004 0.5472 2.2390 1.523255178 RNMTL1 RNA methyltransferase like 1 3.85404398E-07 2.21519634E-06 1.8646 0.7209 0.4832 12.0640 0.8886 0.5580 4.990751112 TRAPPC12 trafficking protein particle complex 12 1.41376783E-08 1.16624676E-07 1.8633 0.9312 1.2665 0.9799 1.0598 1.2546 1.210955839 CENPN centromere protein N 7.07651683E-05 0.000250925899 1.8618 3.5345 0.7650 2.8757 1.4930 0.9971 1.9333122961 ISCA2 iron-sulfur cluster assembly 2 2.61105596E-06 1.24113461E-05 1.8613 2.5565 5.9358 1.9175 0.5191 2.3192 1.150455072 RNF31 ring finger protein 31 3.86338473E-10 5.22901969E-09 1.8606 0.5937 0.7035 1.3362 0.6980 0.7346 1.21403798 KIF5A kinesin family member 5A 0.00259274294 0.006550691223 1.8604 0.8920 2.5558 1.5143 0.8572 1.4442 1.047581887 LAS1L LAS1-like (S. cerevisiae) 2.33201762E-07 1.41328776E-06 1.8598 1.2596 1.4971 1.2043 1.3112 1.4752 1.32272140 EYA3 eyes absent homolog 3 (Drosophila) 8.3534817E-10 1.00549946E-08 1.8591 2.0362 1.4802 2.0144 2.1942 2.1571 2.90243632 INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.00023527818 0.000746743605 1.8585 1.0886 1.3052 1.0161 0.8532 2.3666 1.050894235 GNG8 guanine nucleotide binding protein (G protein), gamma 8 0.01512421099 0.03098784292 1.8585 1.3061 2.6640 2.0832 0.9599 2.0193 1.7010284131 ENDOV hypothetical protein FLJ35220 0.00164297822 0.004349536081 1.8574 0.4531 0.3840 1.1073 0.5685 1.8081 1.1609

25894 PLEKHG4 1.43704975E-06 7.23952937E-06 1.8567 0.7118 1.3706 1.6190 0.4767 1.7615 1.389423659 PLA2G15 phospholipase A2, group XV 4.52104166E-05 0.000166214232 1.8563 0.6609 0.6900 1.2866 0.7944 1.0050 1.422451163 DBR1 debranching RNA lariats 1 3.19061874E-07 1.87229739E-06 1.8559 0.9158 0.7677 1.0682 0.9380 0.7599 1.2621145567 TTC7B tetratricopeptide repeat domain 7B 0.00166745107 0.004403654322 1.8549 0.1928 0.2011 0.3480 0.3141 0.1041 0.33914836 NMT1 N-myristoyltransferase 1 1.04014193E-09 1.21208376E-08 1.8545 0.5894 0.9480 1.0827 0.4695 1.4268 0.903855298 RNF121 Q9H920,ring finger protein 121 6.53185529E-07 3.54680713E-06 1.8545 3.4111 2.2665 1.3772 3.7007 6.2945 1.247110813 UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 3.40112461E-08 2.52418151E-07 1.8543 0.7636 1.5706 1.1422 0.7696 2.5302 1.07171836 SLC26A2 deoxythymidylate kinase (thymidylate kinase) 2.33791378E-05 9.06987827E-05 1.8539 2.5619 3.1372 2.4343 2.0425 3.7873 2.429364132 XYLT2 xylosyltransferase II 4.52480023E-06 2.04292438E-05 1.8534 1.3837 1.9008 2.1123 1.0902 2.3889 1.98969489 PGS1 phosphatidylglycerophosphate synthase 1 3.04290096E-08 2.28148898E-07 1.8526 0.7787 1.2087 1.4971 0.6363 1.6271 1.39477187 TRAF3 TNF receptor-associated factor 3 6.13433782E-09 5.60994097E-08 1.8524 0.8726 1.1884 1.0144 0.9927 1.6286 1.91695366 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00060292229 0.001748666044 1.8515 1.8536 1.7631 1.6374 2.0578 2.6848 2.838880153 EDC3 enhancer of mRNA decapping 3 4.08990332E-10 5.47879131E-09 1.8513 2.3868 1.5234 2.1832 2.5604 1.8444 2.6383170384 FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) 3.0520187E-05 0.000115746131 1.8510 0.6928 1.8381 1.0655 0.8959 2.3073 1.6124113179 ADAT3 hypothetical protein BC011824 0.00088936741 0.002499695629 1.8503 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

137964 AGPAT6 1.9968601E-09 2.11550954E-08 1.8499 1.6907 1.2682 2.0904 1.1764 1.2938 2.125422928 SEPHS2 selenophosphate synthetase 2 5.82013209E-10 7.40567225E-09 1.8498 2.8581 1.9551 2.1695 3.2487 3.1567 2.69821017 CDK2 cyclin-dependent kinase 2 1.36766546E-05 5.58185911E-05 1.8487 6.7167 4.0721 16.9149 3.7604 1.1403 8.182629959 NRBP1 nuclear receptor binding protein 1 8.51314132E-10 1.02135337E-08 1.8486 0.5777 0.9520 0.8409 0.6489 1.1938 1.064810809 STARD10 StAR-related lipid transfer (START) domain containing 10 9.4763955E-06 3.99890759E-05 1.8476 1.3847 2.2861 1.3845 1.2163 1.1705 0.76715423 POLB polymerase (DNA directed), beta 1.51091298E-06 7.57404716E-06 1.8476 2.3198 1.7410 1.6518 2.0900 2.1375 2.2498283951 C16orf91 hypothetical protein LOC283951 7.59554356E-06 3.27788786E-05 1.8473 1.1260 1.3720 1.1584 1.0057 1.3149 1.066479842 ZBTB3 zinc finger and BTB domain containing 3 0.00101437671 0.002813401817 1.8457 1.2083 1.4182 1.5153 1.3249 1.9225 1.831723180 RFTN1 raftlin, lipid raft linker 1 2.20814189E-09 2.30555249E-08 1.8457 2.3526 1.3325 1.7599 1.6381 1.8541 1.832955662 HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 1.17698106E-11 2.95815653E-10 1.8442 1.9362 2.7186 2.4228 1.5471 2.5760 1.616550853 VILL villin-like 4.65555651E-06 2.09781328E-05 1.8440 0.6927 1.0380 0.5329 0.5723 0.8365 0.5283782 CACNB1 calcium channel, voltage-dependent, beta 1 subunit 0.00081005068 0.0022933446 1.8412 0.4856 1.0257 1.1869 0.3155 1.0239 1.134156942 CMC2 chromosome 16 open reading frame 61 2.98235657E-07 1.76297701E-06 1.8408 3.0404 2.6456 1.8286 3.2118 5.7614 3.591010960 LMAN2 lectin, mannose-binding 2 5.19383253E-09 4.86675426E-08 1.8399 1.8404 1.6792 1.5766 1.8716 2.5900 2.134227085 MTBP MDM2 binding protein 0.00163134657 0.004321873947 1.8394 2.6647 0.4637 1.0116 2.8343 0.3109 1.11075395 PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 3.12925692E-06 1.46234738E-05 1.8357 5.2661 0.5319 1.8647 0.9417 0.4185 1.813951295 ECSIT ECSIT signalling integrator 1.24348645E-08 1.03512458E-07 1.8354 1.7257 1.1631 1.2754 1.1405 2.0671 1.782864318 NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) 2.70186033E-06 1.27897389E-05 1.8353 2.5383 1.9284 2.2420 2.0199 1.7258 2.52195528 PPP2R5D protein phosphatase 2, regulatory subunit B', delta 1.0565694E-09 1.22839062E-08 1.8353 0.7540 1.1127 1.0667 0.7730 1.0123 1.21195338 PLD2 phospholipase D2 0.00021737245 0.000693891863 1.8348 1.0639 1.4134 1.6329 0.6974 0.8153 1.971279465 ULBP3 UL16 binding protein 3 0.00400708906 0.009670787388 1.8347 0.6997 0.8316 0.8076 0.7041 1.0746 0.7208150248 C22orf15 chromosome 22 open reading frame 15 0.00719835343 0.016166213614 1.8342 1.5093 1.3073 1.9822 0.8665 0.7683 1.0199

2907 GRINA 8.75030748E-05 0.000304660096 1.8341 0.8340 1.5782 1.3147 0.9051 1.9240 1.213910454 TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 6.15031355E-10 7.75559207E-09 1.8341 1.1828 1.7898 1.1155 1.0037 2.0536 1.417958512 DLGAP3 discs, large (Drosophila) homolog-associated protein 3 0.00714897565 0.016079035333 1.8338 0.1325 0.0248 0.1259 0.2634 0.0125 0.0770100507582 BHLHE40-AS1 BHLHE40 antisense RNA 1 0.01840565088 0.036734904734 1.8333 0.8376 1.6170 1.8916 0.6946 1.5818 3.108711269 DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 8.30235666E-08 5.62270796E-07 1.8331 0.2056 0.2716 0.4056 0.3815 0.2407 0.3744

55334 SLC39A9 7.01565007E-07 3.78476404E-06 1.8325 3.3514 2.9044 2.4618 2.0013 1.4985 1.99641848 DUSP6 dual specificity phosphatase 7 0.00882458681 0.019366184259 1.8321 2.4471 2.9030 2.1993 1.3664 2.1539 2.607979096 C11orf49 chromosome 11 open reading frame 49 6.97444369E-06 3.03018904E-05 1.8298 1.9248 2.0908 1.6869 1.6152 1.7439 1.2550124790 HEXIM2 hexamethylene bis-acetamide inducible 2 0.00169995001 0.004479591368 1.8290 2.5846 2.7210 1.4364 2.2331 2.7557 1.6587

84135 UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) 2.67514028E-06 1.26796792E-05 1.8286 0.6501 2.4256 0.7143 0.4120 1.9871 0.33996253 RTN2 reticulon 2 0.01523649828 0.0311837923 1.8285 1.3327 1.3169 1.2225 0.6500 1.0934 1.32125111 PCNA proliferating cell nuclear antigen 5.45058688E-05 0.000197480675 1.8284 0.4783 1.3770 1.4964 0.6549 1.5280 0.971627304 MOCS3 molybdenum cofactor synthesis 3 1.956173E-06 9.57492449E-06 1.8284 1.3255 1.9401 2.4329 1.0168 0.8252 2.881553918 PELO pelota homolog (Drosophila) 4.49927274E-08 3.2532929E-07 1.8275 0.3321 0.3321 0.3321 0.3970 0.3970 0.39703326 HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 5.23042247E-06 2.33611047E-05 1.8269 0.8874 3.0039 1.4559 1.2439 2.2406 1.551781926 ABHD17A Family with sequence similarity 108, member A1 3.05830184E-09 3.07547007E-08 1.8258 1.6491 1.9399 1.8701 1.2053 1.7208 2.021311079 RER1 retention in endoplasmic reticulum sorting receptor 1 8.36361193E-07 4.43213217E-06 1.8249 1.4944 3.9836 7.4000 1.0497 5.4639 2.710526094 DCAF4 DDB1 and CUL4 associated factor 4 0.00021790444 0.00069546724 1.8245 0.8379 1.3833 0.8972 0.6341 1.7796 1.21988536 CAMK1 calcium/calmodulin-dependent protein kinase I 0.00468459304 0.011106381723 1.8239 0.5982 0.6311 1.1216 0.5649 0.3507 0.71163028 HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 3.18562467E-08 2.37971112E-07 1.8237 2.1420 3.2401 2.0635 1.6887 2.7387 1.821590678 LRSAM1 leucine rich repeat and sterile alpha motif containing 1 6.13602917E-05 0.00022018367 1.8233 0.3932 0.2385 0.3569 0.3804 0.0914 0.2830388324 INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 0.02540427016 0.048499302505 1.8224 2.5427 2.7646 0.8608 1.8328 2.6345 0.37902747 GLUD2 glutamate dehydrogenase 2 0.00011308194 0.000384201053 1.8217 0.1783 0.3622 0.5926 0.3894 0.6608 0.4723147015 DHRS13 dehydrogenase/reductase (SDR family) member 13 6.15692902E-06 2.70236385E-05 1.8216 0.9604 1.2682 1.0912 0.6592 0.9918 1.451751058 ZNF691 zinc finger protein 691 0.00205277356 0.005312034908 1.8215 1.5938 0.9146 1.5106 1.2502 0.7156 1.3976503538 A1BG-AS1 BC040926 0.01518329807 0.031087359921 1.8213 0.6029 0.9806 0.9865 0.4451 1.1602 1.1316131601 TPRA1 transmembrane protein, adipocyte asscociated 1 2.13478281E-10 3.15844141E-09 1.8212 0.9225 2.1802 1.0933 0.8410 1.7163 1.42307297 TYK2 tyrosine kinase 2 9.47151841E-09 8.14800303E-08 1.8211 1.6175 2.0790 2.3004 1.4610 2.9615 2.59442806 GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 4.07957206E-07 2.32507613E-06 1.8211 1.6901 1.5814 1.5431 1.6867 1.3728 1.743730845 EHD3 EH-domain containing 3 0.00971347916 0.021078941952 1.8207 0.8202 0.6800 0.3013 0.7244 0.9981 0.49435725 PTBP1 polypyrimidine tract binding protein 1 2.9799106E-08 2.24069656E-07 1.8206 1.0719 1.0981 0.9371 1.0638 2.5274 2.220580198 MUS81 MUS81 structure-specific endonuclease subunit 5.75066417E-09 5.30080124E-08 1.8204 1.0417 1.3686 1.8834 1.3087 2.3903 2.73488106 PABPN1 poly(A) binding protein, nuclear 1 4.40132495E-07 2.49212921E-06 1.8198 1.3005 1.2728 1.7736 0.9697 1.7450 1.883151647 FAM96B family with sequence similarity 96, member B 9.81332393E-09 8.38284502E-08 1.8188 2.0786 3.0405 3.1036 2.4998 2.9044 3.426311007 CCDC85B coiled-coil domain containing 85B 1.3929227E-07 8.91158388E-07 1.8185 1.9172 2.7907 2.2239 1.4614 2.7528 2.13886301 SARS seryl-tRNA synthetase 4.85763898E-07 2.71516609E-06 1.8184 2.0245 2.0245 1.4800 2.2787 4.4982 2.28471741 DLG3 discs, large homolog 3 (Drosophila) 4.97783232E-05 0.000181619313 1.8179 1.3382 0.8380 1.6744 0.7713 0.5070 1.25236452 SH3BP2 SH3-domain binding protein 2 1.63863129E-10 2.50972934E-09 1.8179 0.8249 1.1792 1.0975 0.5690 1.1581 0.8256

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1

Q9NUJ7,phosphatidylinositol-specific phospholipase C, X domain containing 1

pleckstrin homology domain containing, family G (with RhoGef domain) member 4

1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)

glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)

Q9NUM3,G3V5J8,B4DDK0,C4N9M8,M0QX28,solute carrier family 39, member 9

23523 CABIN1 calcineurin binding protein 1 8.21020573E-08 5.56648902E-07 1.8170 1.1855 1.0380 1.2984 0.8372 0.7947 1.23308890 EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 7.94687534E-09 6.96762506E-08 1.8164 1.1587 2.8393 1.7585 1.1021 1.5999 0.795710269 ZMPSTE24 zinc metallopeptidase STE24 7.90601815E-06 3.39823015E-05 1.8158 3.2732 1.1886 2.1639 3.3059 1.8146 3.99701315 COPB1 coatomer protein complex, subunit beta 1 2.42736975E-08 1.87525921E-07 1.8158 3.4408 2.6405 2.0085 3.2144 2.7544 2.03837486 WRN Werner syndrome, RecQ helicase-like 1.70439506E-05 6.81758024E-05 1.8156 0.1164 0.1273 0.1278 0.2559 0.1142 0.17091785 DNM2 DNA (cytosine-5-)-methyltransferase 3 alpha 8.48693722E-09 7.36690341E-08 1.8151 0.4149 0.4382 0.7434 0.3293 0.2076 0.4583580 BARD1 BRCA1 associated RING domain 1 4.45289642E-05 0.00016410513 1.8135 2.3553 2.5268 1.3646 2.4032 3.9170 1.973129127 RACGAP1 Rac GTPase activating protein 1 4.15820639E-05 0.00015405261 1.8134 2.2206 2.5704 1.5278 1.5596 2.4508 1.7565124923 SGK494 uncharacterized serine/threonine-protein kinase SgK494 0.00208732488 0.00539228052 1.8125 0.0909 0.1181 0.1228 0.0742 0.0445 0.164258489 ABHD17C family with sequence similarity 108, member C1 0.00160055769 0.004248930718 1.8124 2.7291 4.2845 1.7790 1.7501 4.0454 1.801254869 EPS8L1 EPS8-like 1 0.00609445887 0.013980910548 1.8122 0.4474 0.6686 0.8351 0.4560 0.4427 0.705728988 DBNL drebrin-like 0.00010604993 0.000362330635 1.8121 1.8426 1.9799 1.1579 1.2180 2.3534 1.1917339230 CCDC137 coiled-coil domain containing 137 0.00011864708 0.000401317935 1.8102 0.8091 1.8157 4.4925 0.6965 0.7854 1.57376944 VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 1.29039861E-09 1.46812972E-08 1.8098 1.5214 2.3472 1.8620 1.5893 2.5679 2.463355884 WSB2 WD repeat and SOCS box containing 2 4.46616072E-07 2.52180744E-06 1.8092 1.9288 1.8020 2.0481 1.6787 1.7670 1.68169328 GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa 4.58891046E-08 3.30894128E-07 1.8090 1.4251 2.3711 1.9192 1.6269 3.0208 4.2593116841 SNAP47 synaptosomal-associated protein, 47kDa 4.42514649E-08 3.20730967E-07 1.8088 0.5261 2.2765 0.9856 0.6682 1.8531 0.6303148413 LOC148413 uncharacterized LOC148413 1.02579465E-07 6.76165941E-07 1.8087 0.7471 1.3197 1.4767 0.4509 1.1796 0.690310162 LPCAT3 lysophosphatidylcholine acyltransferase 3 2.4746587E-07 1.4888694E-06 1.8081 1.5821 1.9893 1.9374 1.7057 1.8589 2.653129801 ZDHHC8 zinc finger, DHHC-type containing 8 4.43026157E-07 2.50638025E-06 1.8080 0.8673 0.4811 0.8255 0.6105 1.0770 0.901663979 FIGNL1 fidgetin-like 1 0.00013715284 0.000457393065 1.8079 0.8262 1.4520 1.3246 0.5752 1.0987 1.27178624 PSMG1 proteasome (prosome, macropain) assembly chaperone 1 3.69897608E-06 1.70513704E-05 1.8072 1.7051 2.8834 1.6572 1.4222 2.7957 3.298926267 FBXO10 F-box protein 10 0.00111918782 0.003079789136 1.8054 0.8684 1.0338 0.8191 0.4680 0.7883 0.63738898 MTMR2 myotubularin related protein 2 1.22057005E-08 1.01883308E-07 1.8049 2.3863 2.8422 2.0495 2.0056 2.8840 2.07859278 ZBTB22 zinc finger and BTB domain containing 22 1.92607574E-05 7.61264459E-05 1.8032 0.5004 0.5427 0.5807 0.5700 0.5264 0.62401877 E4F1 G protein-coupled receptor 183 3.64980028E-08 2.69124902E-07 1.8023 1.7254 1.6514 1.3763 1.2833 2.5148 2.036584515 MCM8 minichromosome maintenance complex component 8 0.00051443889 0.001515856712 1.8014 5.6281 3.4742 1.2832 3.2240 3.6625 1.003484905 ZNF341 zinc finger protein 341 0.00202846896 0.005252860663 1.8014 0.9622 1.3363 0.9868 0.9203 1.0541 0.858051343 FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 4.5597016E-10 6.01986037E-09 1.7980 1.0237 1.7519 0.9885 1.0252 2.4083 1.317279572 ATP13A3 ATPase type 13A3 1.76279395E-08 1.41332914E-07 1.7979 0.1102 0.1201 0.2054 0.1961 0.1046 0.2217

2526 FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 7.62195151E-06 3.2877313E-05 1.7966 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706772 STAT1 signal transducer and activator of transcription 1, 91kDa 0.00056372678 0.001646222746 1.7964 2.9144 3.1057 2.5485 2.6070 4.3389 2.6777974 CD79B CD79b molecule, immunoglobulin-associated beta 1.49501508E-05 6.04490274E-05 1.7960 1.2649 1.9048 2.2732 1.1834 1.7703 2.627993323 HAUS8 HAUS augmin-like complex, subunit 8 4.48025446E-05 0.000165013524 1.7955 1.4418 4.7146 4.5221 1.1282 3.3789 4.898625807 RHBDD3 rhomboid domain containing 3 0.00021310174 0.000681209775 1.7950 1.1534 20.7573 3.0920 0.1483 8.5256 1.420810726 NUDC nudC nuclear distribution protein 3.35995211E-07 1.95956096E-06 1.7949 1.7993 2.1991 2.1083 1.4714 2.6197 1.8310100128420 LINC00892 long intergenic non-protein coding RNA 892 0.01008502571 0.021789474956 1.7943 2.7543 0.9363 2.1584 2.3306 0.6779 1.22816730 SRP68 signal recognition particle 68kDa 9.64840103E-09 8.26902362E-08 1.7941 1.1952 1.1918 1.3802 1.1855 1.2731 1.5856134430 WDR36 WD repeat domain 36 7.34888356E-07 3.94699859E-06 1.7936 1.8367 1.7460 1.2083 1.5859 3.5897 1.674084255 SLC37A3 solute carrier family 37, member 3 1.35544386E-05 5.5381642E-05 1.7933 1.6457 1.8718 1.2270 1.1255 2.4596 1.60607466 WFS1 Wolfram syndrome 1 (wolframin) 0.00067249469 0.00192901459 1.7931 1.0856 1.0728 0.9700 0.7731 1.1731 1.07075193 PEX12 peroxisomal biogenesis factor 12 0.00199022913 0.005160418144 1.7913 2.5947 1.5044 2.0726 2.7451 1.4276 2.42112108 ETFA electron-transfer-flavoprotein, alpha polypeptide 1.04569587E-08 8.88282426E-08 1.7902 2.5355 1.5120 1.5548 2.4937 1.4260 1.98491612 DAPK1 death-associated protein kinase 1 0.02524660072 0.048248707081 1.7900 0.4664 0.5652 0.5641 0.3975 0.3381 0.575310055 SAE1 SUMO1 activating enzyme subunit 1 0.00072043207 0.002058119898 1.7900 1.4536 2.5824 1.4707 1.4948 3.0894 1.681763905 MANBAL mannosidase, beta A, lysosomal-like 0.00011071426 0.000376857477 1.7899 2.5946 3.5605 1.9242 2.6966 3.5478 2.1333374655 ZNF710 zinc finger protein 710 1.54502102E-07 9.77853277E-07 1.7895 1.2885 2.9143 2.1263 1.1775 3.0092 2.267760488 MRPS35 mitochondrial ribosomal protein S35 5.58866473E-07 3.0804248E-06 1.7892 2.3559 3.9106 1.7946 2.2206 5.8077 1.87475976 UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 1.10307143E-08 9.33116724E-08 1.7890 0.6903 0.5352 0.8914 0.5283 0.9056 1.311829086 BABAM1 BRISC and BRCA1 A complex member 1 1.24769103E-10 2.00156369E-09 1.7885 1.8187 1.6333 2.3195 1.5348 2.3354 2.078410195 ALG3 ALG3, alpha-1,3- mannosyltransferase 1.01532281E-07 6.7047994E-07 1.7880 3.1643 3.2981 2.0434 3.4093 5.0925 2.58009918 NCAPD2 non-SMC condensin I complex, subunit D2 7.13554228E-07 3.8471711E-06 1.7874 4.4361 1.8967 1.8985 3.0486 1.5545 2.279057514 ARHGAP31 Rho GTPase activating protein 31 0.00040030559 0.001209788894 1.7872 2.5215 3.4264 2.3040 1.9852 3.2045 2.217110658 CELF1 CUGBP, Elav-like family member 1 7.06996574E-09 6.30158117E-08 1.7869 0.8852 1.3849 1.0082 0.7580 1.3687 0.891423141 ANKLE2 ankyrin repeat and LEM domain containing 2 6.19772386E-09 5.65093864E-08 1.7853 1.7599 0.6670 0.7833 1.1975 0.8020 1.069681559 TRIM11 tripartite motif containing 11 5.42272489E-11 1.00792905E-09 1.7848 2.3060 1.7961 1.2388 1.8942 2.1400 2.18266307 MSMO1 methylsterol monooxygenase 1 4.13022491E-05 0.000153233441 1.7848 2.5756 2.5058 1.7382 2.4628 4.0984 2.22409955 HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.00336172238 0.008250556263 1.7841 0.1962 0.5436 1.8363 0.4080 0.2217 1.590279767 ELMO3 engulfment and cell motility 3 0.00239631721 0.006100809271 1.7837 0.0940 0.0354 0.3392 0.3245 0.0172 0.146579735 TBC1D17 TBC1 domain family, member 17 1.82746509E-05 7.26532681E-05 1.7835 0.1807 0.3326 0.6825 0.1999 0.3913 0.2762728752 LOC728752 uncharacterized LOC728752 0.0030483735 0.007574102347 1.7827 2.0654 0.9553 0.3202 1.2105 0.3763 1.174684292 WDR83 WD repeat domain 83 1.14833652E-06 5.90720858E-06 1.7815 0.3421 2.5920 1.3504 0.3005 1.9711 1.04119746 CLSTN3 calsyntenin 3 6.00076849E-06 2.64143681E-05 1.7813 0.9488 1.2739 1.2035 0.7934 1.6808 1.089011267 SNF8 SNF8, ESCRT-II complex subunit 5.43995152E-09 5.05846281E-08 1.7813 2.4406 2.5239 1.6209 2.2369 4.5301 1.956610436 EMG1 EMG1 N1-specific pseudouridine methyltransferase 0.00014135141 0.000470450452 1.7810 0.3745 1.9379 4.3797 0.4047 1.2593 3.9613644656 LOC644656 uncharacterized LOC644656 0.00614977599 0.014093654454 1.7808 4.1364 3.2585 2.0586 3.5087 4.0366 1.945954107 POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 6.07206216E-07 3.32580095E-06 1.7801 1.6114 1.1040 1.1727 1.5772 0.4314 0.4026387032 ZKSCAN4 zinc finger with KRAB and SCAN domains 4 0.00155311755 0.004135008574 1.7792 1.2884 1.1378 1.0387 1.3695 1.4027 1.908454797 MED18 mediator complex subunit 18 0.00012767267 0.000428829971 1.7792 3.5357 1.8184 1.7730 3.7149 2.0096 2.02802923 PDIA3 protein disulfide isomerase family A, member 3 1.30347487E-06 6.62690396E-06 1.7791 0.3321 0.3321 0.3321 0.3970 0.3970 0.397051117 COQ4 coenzyme Q4 1.29509297E-09 1.47255375E-08 1.7790 1.9062 6.5618 1.4671 1.4955 12.1742 1.442123381 SMG5 SMG5 nonsense mediated mRNA decay factor 2.16656522E-09 2.26992429E-08 1.7788 2.9338 7.7714 3.5585 2.0273 2.8260 2.0683283237 TTC9C tetratricopeptide repeat domain 9C 1.48239603E-05 5.99653315E-05 1.7777 3.7498 2.9298 2.4661 4.0242 4.3403 4.113379693 YRDC yrdC domain containing (E. coli) 4.51018171E-05 0.000165981954 1.7777 1.3346 1.8216 2.2918 0.4748 2.8156 1.445264793 CEP85 coiled-coil domain containing 21 2.99067296E-07 1.76617894E-06 1.7772 0.8568 1.1080 0.8992 0.8678 1.2790 1.4421148523 C1orf51 chromosome 1 open reading frame 51 0.01631307648 0.033064063618 1.7768 1.2551 1.8404 1.7435 0.9595 1.0884 1.051626578 OSTF1 osteoclast stimulating factor 1 7.94137655E-07 4.22676471E-06 1.7743 8.3108 4.3637 1.7840 5.7532 4.0778 2.913125917 THUMPD3 THUMP domain containing 3 5.31259337E-10 6.84567743E-09 1.7741 2.1519 1.7672 2.1839 2.4581 2.4497 2.4225129790 C7orf13 chromosome 7 open reading frame 13 0.01125245418 0.023938158432 1.7731 0.3338 0.3254 0.8987 1.1277 0.3972 0.4047286827 TRIM59 tripartite motif-containing 59 0.00145868387 0.003909221413 1.7722 0.3321 0.3321 0.3321 0.3970 0.3970 0.397057594 HOMEZ homeobox and leucine zipper encoding 4.58436348E-05 0.000168406694 1.7714 1.4202 1.3855 1.3505 1.2941 1.5153 1.504210493 VAT1 vesicle amine transport 1 1.13007164E-05 4.68968182E-05 1.7713 1.1747 1.4574 1.4590 0.8590 1.5792 1.515591893 FDXACB1 ferredoxin-fold anticodon binding domain containing 1 0.00233927627 0.005969728482 1.7712 0.3321 0.3321 0.3321 0.3970 0.3970 0.397025926 NOL11 nucleolar protein 11 8.03758511E-09 7.03028986E-08 1.7711 1.9186 2.2084 1.6038 1.8878 3.0995 1.6304540 ATP7B ATPase, Cu++ transporting, beta polypeptide 0.00212210243 0.00547283777 1.7711 0.3268 0.9380 0.6328 0.2687 0.4229 0.370325921 ZDHHC5 zinc finger, DHHC-type containing 5 2.01774161E-08 1.59810033E-07 1.7683 1.3585 1.7298 1.2683 1.3742 2.1092 2.16546635 SNRPE small nuclear ribonucleoprotein polypeptide E 4.78175147E-08 3.42770352E-07 1.7670 1.9195 3.4991 1.6905 2.3255 4.9562 2.067881037 CLPTM1L CLPTM1-like 2.84329108E-07 1.6867732E-06 1.7662 1.3682 3.2326 0.9151 1.1029 3.5216 1.244910409 BASP1 brain abundant, membrane attached signal protein 1 0.01917138001 0.038042946959 1.7660 0.5682 1.2703 0.3002 0.6672 0.6035 0.4632

6391 SDHC 1.25213102E-10 2.00348165E-09 1.7653 2.1307 1.8114 1.8556 2.2494 2.8060 2.09242000 ELF4 E74-like factor 4 (ets domain transcription factor) 5.02782378E-09 4.73304462E-08 1.7651 1.2638 2.9995 1.8400 1.3749 3.8614 2.6343133686 NADK2 NAD kinase 2, mitochondrial 0.00012576981 0.000423138651 1.7650 0.5990 0.6878 0.6668 0.6560 0.6610 0.887265123 INTS3 integrator complex subunit 3 6.65890197E-07 3.60828757E-06 1.7647 0.5699 0.7056 0.6113 0.5627 0.6889 0.70352764 GMFB glia maturation factor, beta 3.91565866E-07 2.24707648E-06 1.7646 2.1338 2.3139 2.6399 1.5611 2.8665 2.526323567 ZNF346 zinc finger protein 346 1.6749121E-05 6.71593938E-05 1.7642 2.5246 2.5290 2.1795 2.4066 3.8603 2.4931284837 LOC284837 hypothetical protein LOC284837 0.01780995865 0.0357058991 1.7636 0.3091 0.4043 0.3607 0.2835 0.1327 0.210481875 ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 5.94839923E-09 5.45354495E-08 1.7623 2.5755 3.6335 2.2201 1.2647 2.7454 1.225181556 VWA9 von Willebrand factor A domain containing 9 5.13073611E-07 2.85210861E-06 1.7618 0.4555 1.1945 2.8011 0.0715 0.4346 1.68717347 UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 0.00020670889 0.000662861492 1.7606 2.0442 2.1587 1.4013 1.6215 1.7728 1.571510691 GMEB1 glucocorticoid modulatory element binding protein 1 3.1662728E-06 1.47737836E-05 1.7606 2.0906 3.9398 2.3922 1.8785 3.7356 3.14792752 GLUL glutamate-ammonia ligase 0.01902386932 0.037787166011 1.7597 0.6484 0.9397 0.8164 0.6489 0.7620 0.993054443 ANLN anillin, actin binding protein 0.00861530481 0.018963841649 1.7597 0.3231 0.0929 0.1704 0.3039 0.0476 0.2648387036 GUSBP2 glucuronidase, beta pseudogene 2 1.27445996E-05 5.2318428E-05 1.7595 0.6309 2.5072 1.1148 0.6664 0.9464 0.7937152992 TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) 3.69919179E-06 1.70513704E-05 1.7595 0.1987 0.6697 0.3789 0.4314 0.4156 0.2968441518 FAM127C family with sequence similarity 127, member C 0.01344422776 0.027978693586 1.7592 0.9577 1.2403 1.5514 0.8452 1.1988 1.545154503 ZDHHC13 zinc finger, DHHC-type containing 13 0.00039315211 0.001190138398 1.7589 1.3169 1.5229 1.7398 1.0032 1.4781 1.935755048 VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 0.00095647699 0.002669836166 1.7574 0.9987 1.5997 1.9636 0.8051 1.3825 1.9796140901 STK35 serine/threonine kinase 35 4.74479606E-09 4.51781728E-08 1.7570 2.0399 1.3676 1.4865 1.8400 1.4796 2.09279953 HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 0.00057701764 0.00168127353 1.7567 2.6315 2.6028 2.0214 2.1167 2.5208 2.69761119 CHKA choline kinase alpha 0.00018052666 0.000585685929 1.7564 1.2173 2.1790 2.0276 0.5287 1.4637 1.98065796 PTPRK protein tyrosine phosphatase, receptor type, K 0.00175117882 0.004598669061 1.7550 0.7521 1.0014 0.9140 0.8809 0.9663 1.02579532 BAG2 BCL2-associated athanogene 2 2.84063025E-06 1.33876698E-05 1.7546 2.0634 2.0940 2.0701 1.9000 2.3130 2.268555254 TMEM39A transmembrane protein 39A 3.08663725E-07 1.81580927E-06 1.7543 2.6051 3.6220 2.3012 2.9786 4.9292 2.6753597 BCL2A1 BCL2-related protein A1 2.78601671E-05 0.0001066543 1.7536 2.4555 1.9561 1.3947 1.8263 2.0083 1.65713149 HMGB3 high mobility group box 3 0.00554869087 0.012882551403 1.7532 0.8507 1.7743 1.7001 0.6253 1.4364 2.161910450 PPIE peptidylprolyl isomerase E (cyclophilin E) 3.26511833E-09 3.25123935E-08 1.7528 0.8820 1.0349 1.1862 0.8452 1.1496 1.1749203054 ADCK5 aarF domain containing kinase 5 0.00077715073 0.002207040439 1.7519 0.5915 0.8945 0.9470 0.6327 1.0374 0.905110121 ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 3.06863807E-09 3.0824714E-08 1.7495 2.2269 1.2933 1.3436 2.8363 2.1575 2.893051259 TMEM216 transmembrane protein 216 0.00017483433 0.000568935506 1.7494 2.8721 1.8895 1.8958 2.1892 1.9552 1.88182306 FOXD2 forkhead box D2 0.00652094777 0.014851147649 1.7491 1.0857 0.8099 1.9831 0.6176 1.0652 1.4930254887 ZDHHC23 zinc finger, DHHC-type containing 23 0.00274680803 0.006889454541 1.7479 0.7328 0.8916 0.8524 0.6996 0.7144 0.6319586 BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.02021901303 0.039832000655 1.7479 1.6869 1.7650 1.5891 1.4334 1.0149 1.2264347746 PWARSN Prader Willi/Angelman region RNA, SNRPN neighbor 0.02555049463 0.048737721877 1.7479 0.0426 0.0064 0.2009 0.3360 0.1603 0.362610768 AHCYL1 adenosylhomocysteinase-like 1 7.65901018E-09 6.73786394E-08 1.7474 0.6581 1.5660 0.9656 0.4416 1.9210 0.825625829 TMEM184B transmembrane protein 184B 4.60887072E-08 3.32202311E-07 1.7472 2.0813 1.2048 2.6240 1.3712 1.0120 1.8472150465 TTL tubulin tyrosine ligase 1.79305997E-08 1.4350763E-07 1.7469 2.1133 6.8235 1.8397 1.6581 9.0799 2.705290459 ERI1 exoribonuclease 1 4.68551068E-07 2.63345589E-06 1.7468 1.3618 1.7060 1.5400 0.9881 2.1679 1.898151043 ZBTB7B zinc finger and BTB domain containing 7B 1.1722057E-06 6.01982646E-06 1.7451 1.4743 3.1644 1.4783 1.2883 2.7699 1.832779847 TMEM180 transmembrane protein 180 0.00014301983 0.000475483674 1.7448 0.6969 1.1675 1.0094 0.7543 1.1115 0.658084128 WDR75 WD repeat domain 75 0.00041183828 0.001240743461 1.7446 2.0771 2.1658 1.7746 2.8870 3.3574 2.53938570 KHSRP KH-type splicing regulatory protein 6.29190323E-07 3.4319841E-06 1.7436 1.2344 2.2720 2.2027 0.8726 3.3794 2.44477419 VDAC3 voltage-dependent anion channel 3 2.28496071E-08 1.78346015E-07 1.7427 1.2524 1.8022 1.2250 1.0924 1.7917 1.437179149 ZSCAN5A zinc finger and SCAN domain containing 5A 0.00262894883 0.00663299544 1.7412 1.0176 1.5025 1.1310 1.1904 1.5312 1.391029982 NRBF2 nuclear receptor binding factor 2 2.1624864E-06 1.04653211E-05 1.7407 1.6640 2.6331 1.0301 1.9301 2.8811 1.70601678 TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 7.69155989E-05 0.000271255803 1.7399 1.7145 2.2220 1.5104 2.3297 3.0212 2.56065394 EXOSC10 exosome component 10 4.61978767E-10 6.08859463E-09 1.7396 1.1394 1.3732 1.7739 1.0086 2.0199 2.4951140680 C20orf96 chromosome 20 open reading frame 96 0.00353085252 0.008628129008 1.7381 1.8187 2.8659 2.0665 1.7584 2.0984 1.803525989 ULK3 unc-51 like kinase 3 1.29939322E-08 1.07822493E-07 1.7368 1.3882 1.7186 1.6672 1.0788 1.5896 1.7501148022 TICAM1 toll-like receptor adaptor molecule 1 1.17128522E-09 1.34517433E-08 1.7365 0.8474 4.5898 2.1330 0.7841 6.0509 2.42845933 RBL1 retinoblastoma-like 1 5.86941668E-07 3.22350411E-06 1.7357 1.7309 1.7172 1.8381 1.4957 2.7212 1.98161499 CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 7.12669187E-07 3.84353346E-06 1.7354 0.6625 0.6463 0.7227 0.9049 0.7525 1.152584787 SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.00144255119 0.003869391566 1.7346 1.7402 1.9027 2.4149 1.5581 1.4730 2.2084

succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa

90390 MED30 mediator complex subunit 30 1.19631234E-06 6.13156215E-06 1.7343 2.1350 2.9984 1.7732 2.4433 4.1206 2.70522744 GLS glutaminase 0.0003710147 0.001127420674 1.7343 0.5282 1.1575 0.7774 0.7291 1.6784 1.2519101 ADAM8 ADAM metallopeptidase domain 8 1.69482346E-05 6.78374901E-05 1.7321 2.1089 1.7169 1.7904 1.6407 1.6909 1.7485246243 RNASEH1 ribonuclease H1 2.29086588E-07 1.39065453E-06 1.7301 14.6837 2.6011 1.3708 12.2227 1.0817 2.145722924 MAPRE3 microtubule-associated protein, RP/EB family, member 3 0.00245937429 0.006246591925 1.7297 0.8016 1.0596 0.8868 0.5934 0.8797 0.702381876 RAB1B RAB1B, member RAS oncogene family 3.48634865E-08 2.57905112E-07 1.7282 2.2272 2.5105 1.9572 2.2688 3.2209 3.309492595 ZNF764 zinc finger protein 764 1.33277649E-06 6.76646069E-06 1.7280 2.3783 1.7880 1.4437 1.8041 2.2998 2.2420116986 AGAP2 centaurin, gamma 1 3.51764226E-08 2.60009544E-07 1.7278 1.5469 2.4950 1.3250 1.4232 2.4677 1.368229888 STRN4 striatin, calmodulin binding protein 4 1.42541662E-09 1.59006181E-08 1.7272 0.5774 0.5936 0.8591 0.2363 0.4900 0.604810314 LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 1.8957749E-07 1.17781704E-06 1.7272 4.1895 4.2226 1.5506 3.4119 5.0940 2.00355202 PFDN2 prefoldin subunit 2 9.45353463E-07 4.94587639E-06 1.7271 0.3321 0.3321 0.3321 0.3970 0.3970 0.39704123 MAN2C1 mannosidase, alpha, class 2C, member 1 2.6750854E-05 0.000102644184 1.7269 1.3628 1.2096 2.1691 1.1693 1.6618 2.5855684 BST2 bone marrow stromal cell antigen 2 0.00025275866 0.000798065692 1.7265 2.9457 3.6109 2.6641 2.5886 3.3831 2.992980824 DUSP16 dual specificity phosphatase 16 5.13882436E-05 0.000186933304 1.7263 1.1362 1.3029 0.7733 1.1441 1.8529 1.0115823 CAPN1 calpain 1, (mu/I) large subunit 4.08071636E-08 2.98609729E-07 1.7254 2.1822 2.3424 1.6279 1.3149 2.8066 1.826455666 NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 3.71834388E-08 2.73847559E-07 1.7250 0.4769 0.7549 0.9732 2.0811 0.2859 1.02299046 DOK2 docking protein 2, 56kDa 1.8446992E-08 1.47382352E-07 1.7246 2.6581 2.5670 2.9037 2.0849 2.5567 2.6348129401 NUP35 nucleoporin 35kDa 0.00017959827 0.000583067156 1.7241 1.4528 0.8903 0.8060 1.9067 1.2662 1.205610109 ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 3.40452548E-08 2.52567964E-07 1.7235 1.2492 1.7599 0.8184 1.4157 2.9171 1.2214152877 FAM53A family with sequence similarity 53, member A 0.0137070988 0.028425389764 1.7233 1.5018 2.2116 1.4000 0.8121 2.0949 1.50297158 TP53BP1 tumor protein p53 binding protein 1 5.36836712E-09 5.00718754E-08 1.7231 1.1628 1.2517 1.0516 1.0280 1.1632 1.123984766 EFCAB4B EF-hand calcium binding domain 4B 1.04104846E-06 5.40398794E-06 1.7224 1.1918 1.4689 1.3907 1.0283 1.8306 1.446957215 THAP11 THAP domain containing 11 1.98258895E-09 2.10248782E-08 1.7222 1.0614 2.6387 1.6550 1.1445 3.1914 2.44795875 RABGGTA Rab geranylgeranyltransferase, alpha subunit 1.0642866E-09 1.23549204E-08 1.7207 1.2529 3.2419 1.6785 1.1390 2.6437 1.5060261734 NPHP4 nephronophthisis 4 0.00015796799 0.000519321915 1.7203 2.3435 2.0238 0.8775 2.8828 2.0800 1.175684804 MFSD9 major facilitator superfamily domain containing 9 0.00121532214 0.003317353771 1.7196 1.6478 0.2728 1.0046 0.9319 0.3442 0.60639567 GTPBP1 GTP binding protein 1 3.72216816E-09 3.64672689E-08 1.7194 1.8254 1.6974 2.0773 1.6618 1.8339 2.2542

2972 BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 6.17790169E-08 4.31838637E-07 1.7191 0.4982 1.1280 0.7262 0.3396 0.8661 0.484855687 TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 5.51797372E-07 3.0454326E-06 1.7183 1.5253 1.5622 1.2154 1.5662 2.1164 2.062255709 KBTBD4 kelch repeat and BTB (POZ) domain containing 4 3.12681374E-05 0.000118361592 1.7182 2.3569 1.3689 0.8502 1.5177 1.8281 0.403010237 SLC35B1 solute carrier family 35, member B1 0.00018213375 0.000590375709 1.7182 1.4285 1.2659 1.6827 1.6352 1.3570 1.84358394 PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 2.30685552E-06 1.1106947E-05 1.7181 1.0946 0.9137 1.0292 1.4586 1.6397 1.45452629 GBA glucosidase, beta, acid 0.00023500104 0.000745993583 1.7176 1.6570 1.4127 1.8246 1.2869 1.2750 1.6507440275 EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 1.35530587E-08 1.12156471E-07 1.7173 0.4073 0.3645 0.5186 0.4146 0.3298 0.527292922 CCDC102A coiled-coil domain containing 102A 5.09796506E-05 0.000185631761 1.7168 1.5466 2.0841 1.7446 1.1600 2.0438 1.933151001 MTERFD1 MTERF domain containing 1 0.00019097488 0.000616191596 1.7165 0.7642 2.6289 1.5789 0.5146 4.1132 1.31151534 CYB561 cytochrome b561 0.01409998744 0.029160721047 1.7162 0.8505 0.9137 0.7754 0.4623 0.5970 0.52632956 MSH6 mutS homolog 6 4.44384227E-06 2.01034627E-05 1.7160 1.6263 1.6248 1.7930 1.6234 1.9121 2.076679602 ADIPOR2 adiponectin receptor 2 1.93743855E-07 1.20002974E-06 1.7153 1.9988 4.5950 1.7239 1.6220 5.9738 2.048884740 AFAP1-AS1 hypothetical protein MGC10981 0.0196243002 0.038794245734 1.7148 0.0966 0.0571 0.2902 0.1212 0.4825 0.130623288 IQCE IQ motif containing E 9.92206092E-05 0.000341423535 1.7142 1.5634 1.0623 1.2933 0.9161 0.8991 1.1684115024 NT5C3B 5'-nucleotidase, cytosolic III-like 1.15520212E-07 7.53045065E-07 1.7142 2.2950 2.5064 2.1253 1.4606 2.8757 2.14838878 SQSTM1 sequestosome 1 5.36507781E-08 3.79522655E-07 1.7141 1.1798 2.0018 1.7321 0.6642 1.5789 1.631257048 PLSCR3 phospholipid scramblase 3 0.00669813797 0.015197861299 1.7140 1.5225 2.2859 1.9254 1.7989 2.8952 3.008910868 USP20 ubiquitin specific peptidase 20 1.18547001E-07 7.70850817E-07 1.7126 5.5453 4.2898 1.4136 1.9649 4.7847 1.547311068 CYB561D2 cytochrome b561 family, member D2 2.24826714E-06 1.08405341E-05 1.7123 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970284338 PRR19 hypothetical LOC284338 0.02283954511 0.04424556492 1.7118 0.7897 1.5603 0.8180 0.2810 2.3602 0.39935580 PRKCD protein kinase C, delta 2.0515378E-06 9.98819576E-06 1.7110 0.3881 0.9899 0.7321 0.4619 0.5943 0.91259409 PEX16 peroxisomal biogenesis factor 16 3.01249701E-09 3.03609186E-08 1.7106 2.2900 2.5367 1.8411 2.0804 4.1861 2.59284190 MDH1 malate dehydrogenase 1, NAD (soluble) 1.14847938E-08 9.66160926E-08 1.7097 2.2853 4.4509 1.7524 1.9694 3.8385 0.93241522 CTSZ cathepsin Z 0.01411682618 0.029185635662 1.7097 1.0554 1.3327 1.3095 0.7923 1.7815 1.482910228 STX6 syntaxin 6 7.25137131E-10 8.90437208E-09 1.7083 1.9508 1.7052 1.6014 1.9015 2.4198 2.559355131 RBM28 RNA binding motif protein 28 1.68645399E-06 8.37361068E-06 1.7081 2.3066 1.9947 1.6773 2.3436 2.6151 1.9846170394 PWWP2B PWWP domain containing 2B 0.00043275531 0.001294581706 1.7075 1.2851 1.7458 1.3238 0.9369 1.2187 1.050879596 RNF219 chromosome 13 open reading frame 7 1.14889942E-05 4.75916803E-05 1.7069 2.9040 1.5556 1.4211 2.9417 1.9865 1.459923545 ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 2.68196009E-05 0.000102864766 1.7069 1.8358 2.4926 2.1846 1.3584 3.5636 3.219351023 MRPS18C mitochondrial ribosomal protein S18C 1.26194708E-07 8.15068823E-07 1.7066 1.8351 12.1950 1.5285 0.8683 5.7543 0.4857113419 TEX261 testis expressed 261 7.38340108E-08 5.05847411E-07 1.7057 2.0400 1.8607 2.2301 2.0937 1.7613 1.97659570 GOSR2 golgi SNAP receptor complex member 2 6.04911316E-09 5.54032059E-08 1.7055 2.9128 1.5618 1.3452 2.5696 2.2934 2.12298503 PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.00475705954 0.011267953311 1.7037 0.8770 1.2316 0.7605 0.8498 0.7575 0.6519127933 UHMK1 U2AF homology motif (UHM) kinase 1 1.60132292E-08 1.29983885E-07 1.7034 1.8733 1.3271 1.4903 1.6552 2.1019 1.556490933 TRIM41 tripartite motif containing 41 1.61332763E-09 1.77049384E-08 1.7030 0.8210 0.9946 1.0308 1.0101 1.0899 1.4892741 ZNHIT2 zinc finger, HIT-type containing 2 1.64039446E-06 8.17378992E-06 1.7026 0.5673 2.4896 1.0961 0.3735 3.3328 1.407210890 RAB10 RAB10, member RAS oncogene family 1.61849189E-08 1.31144495E-07 1.7025 1.4248 2.5551 1.6158 1.8634 7.4135 4.149279029 SPATA5L1 spermatogenesis associated 5-like 1 1.25751258E-05 5.17040276E-05 1.7023 2.0310 2.5298 1.6786 2.4081 5.5335 2.842064087 MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 3.61048061E-10 4.95275538E-09 1.7017 1.3902 1.7758 1.1933 1.3691 1.8940 1.258654883 CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 3.72320027E-05 0.000139320736 1.7007 1.3693 1.5276 1.3598 1.6244 1.7660 1.157865009 NDRG4 NDRG family member 4 0.02228541893 0.043314453223 1.7003 0.3907 0.6622 0.6857 0.2501 0.3010 0.598623279 NUP160 nucleoporin 160kDa 5.62409293E-08 3.95548214E-07 1.7002 2.1128 2.0022 1.7713 2.4895 3.6376 1.81609917 FAM20B family with sequence similarity 20, member B 3.98964496E-08 2.92413929E-07 1.6987 1.9938 2.2500 1.2981 1.6124 2.9378 2.081310808 HSPH1 heat shock 105kDa/110kDa protein 1 0.00258457465 0.006532763593 1.6987 1.9759 3.1941 1.8300 2.2250 4.1708 3.285565108 MARCKSL1 MARCKS-like 1 1.26760318E-05 5.20631239E-05 1.6981 1.0210 1.4401 1.2268 0.7596 0.9520 1.20689948 WDR1 WD repeat domain 1 6.81421901E-09 6.14254611E-08 1.6978 1.9455 1.2359 1.1059 1.6713 1.1467 1.21753035 HARS histidyl-tRNA synthetase 7.51924147E-09 6.65012489E-08 1.6974 1.0502 0.8228 1.1448 0.5418 0.4120 0.684228511 NKIRAS2 NFKB inhibitor interacting Ras-like 2 7.78460629E-07 4.15300222E-06 1.6967 1.0036 1.3606 1.0113 0.9316 1.7151 0.9692266655 LINC00094 FLJ35348 1.73106514E-06 8.57879637E-06 1.6967 0.8610 1.4224 1.5102 0.5828 1.3451 1.5762302 ANXA2 annexin A2 0.00725593876 0.016285531622 1.6963 1.8174 1.8012 1.9925 1.0508 1.5758 2.25225127 CDK16 cyclin-dependent kinase 16 2.79728144E-07 1.66379969E-06 1.6948 0.9758 0.9662 1.0118 1.0110 1.2838 1.1732728377 ARHGEF34P Rho guanine nucleotide exchange factor (GEF) 34, pseudogene 3.99343831E-05 0.000148550702 1.6934 1.2787 1.3318 1.1145 1.0615 1.1377 1.01161477 CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 5.47664089E-09 5.08481617E-08 1.6930 1.6156 1.9179 2.1113 1.0202 2.0055 1.69448563 THOC5 THO complex 5 1.45470882E-08 1.19248271E-07 1.6928 0.7544 0.7285 0.8116 0.6934 1.0058 0.80336867 TACC1 transforming, acidic coiled-coil containing protein 1 1.22918762E-08 1.02462209E-07 1.6927 0.8860 1.3285 1.2941 0.7314 1.1390 0.956255156 ARMC1 armadillo repeat containing 1 2.96356734E-08 2.22992694E-07 1.6917 1.9955 3.8757 1.8887 1.5329 6.2425 2.234254935 DUSP23 dual specificity phosphatase 23 1.16436757E-05 4.81669102E-05 1.6917 1.7675 1.8664 1.4005 1.2087 1.8605 1.336429095 ORMDL2 ORM1-like 2 (S. cerevisiae) 1.14367498E-07 7.47130115E-07 1.6896 24.7984 0.4276 2.2114 14.4745 0.2383 1.268683667 SESN2 sestrin 2 1.19392938E-05 4.93339613E-05 1.6881 1.6781 2.4076 1.9660 1.0810 2.3693 2.160963897 HEATR6 HEAT repeat containing 6 1.75481487E-06 8.68707051E-06 1.6880 0.4999 0.9467 0.9805 0.5714 1.2631 1.15189183 ZW10 zw10 kinetochore protein 1.11402631E-05 4.63045695E-05 1.6879 1.4269 1.4446 1.5500 1.9599 3.5925 2.602851559 NT5DC3 5'-nucleotidase domain containing 3 0.00128773209 0.003494644405 1.6875 1.3860 2.6424 1.9539 1.1819 1.8565 1.8619435 ASL argininosuccinate lyase 0.00065628507 0.00188844737 1.6872 1.3913 1.3933 1.9736 0.8396 1.1104 2.200884629 TNRC18 trinucleotide repeat containing 18 6.35654485E-08 4.42632574E-07 1.6870 0.4343 0.6278 0.5307 0.3913 0.6244 0.4455144404 TMEM120B transmembrane protein 120B 1.81846355E-06 8.96572207E-06 1.6870 2.1931 2.1127 1.9165 1.7421 2.8302 2.31951407 CRY1 cryptochrome circadian clock 1 1.46357175E-05 5.93088999E-05 1.6869 1.6549 1.9629 1.5411 2.0108 3.1692 2.8289643853 TMPPE transmembrane protein with metallophosphoesterase domain 0.00359653982 0.008767975407 1.6862 0.3321 0.3321 0.3321 0.3970 0.3970 0.397010213 PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 2.1048216E-06 1.02230995E-05 1.6860 2.0905 2.2131 1.4079 2.1129 2.5493 1.698455665 URGCP upregulator of cell proliferation 2.27831527E-09 2.36665017E-08 1.6860 1.4501 1.3857 1.5907 1.5505 0.7567 0.73549276 COPB2 coatomer protein complex, subunit beta 2 (beta prime) 8.02566024E-09 7.02658667E-08 1.6853 1.8387 2.0792 1.6877 1.8494 3.1017 2.274354887 UHRF1BP1 UHRF1 binding protein 1 2.62049457E-09 2.68244687E-08 1.6850 1.6868 1.7313 1.3802 1.5693 1.5845 1.76908871 SYNJ2 synaptojanin 2 2.80633932E-06 1.32431385E-05 1.6842 0.6846 0.8388 0.7197 0.4378 0.7294 0.79621819 DRG2 AT rich interactive domain 3A (BRIGHT-like) 4.94004383E-10 6.41538599E-09 1.6833 2.2865 1.2676 2.0452 1.8754 1.4564 2.171784337 ELOF1 elongation factor 1 homolog (S. cerevisiae) 4.06997801E-10 5.4601056E-09 1.6825 1.3582 1.7089 2.0490 1.4886 2.1138 1.988527044 SND1 staphylococcal nuclease and tudor domain containing 1 1.2081986E-07 7.8367784E-07 1.6816 1.4605 2.3350 1.5445 1.4954 3.0527 2.172651272 BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.7684002E-08 1.41720212E-07 1.6813 2.2571 2.8545 1.9646 2.5012 3.8755 3.07166483 ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 3.77329442E-07 2.17647333E-06 1.6799 0.7354 1.0981 1.2703 0.5991 1.3715 1.33517001 PRDX2 peroxiredoxin 2 8.75010031E-08 5.88449882E-07 1.6783 1.4239 2.0705 1.9474 1.2968 2.7908 2.484737 ACADVL acyl-CoA dehydrogenase, very long chain 2.69464633E-05 0.000103264634 1.6778 0.6964 1.4078 1.4267 0.4218 0.4628 0.97252222 FDFT1 farnesyl-diphosphate farnesyltransferase 1 8.68452686E-08 5.84901123E-07 1.6776 1.2889 1.8658 1.2999 1.0134 2.3117 1.43848718 TNFRSF25 tumor necrosis factor receptor superfamily, member 25 1.38668195E-05 5.64937627E-05 1.6770 1.0674 1.4138 1.2808 1.1165 1.4443 1.3084200942 KLHDC8B kelch domain containing 8B 0.00989451729 0.021436781736 1.6769 0.8076 0.8897 1.0175 0.5862 0.7386 0.984755697 VAC14 Vac14 homolog (S. cerevisiae) 3.89903225E-09 3.80572208E-08 1.6766 0.7021 0.4204 0.6070 0.7645 0.3975 0.59742896 GRN granulin 0.01292399267 0.027016038674 1.6763 1.9668 3.4713 1.6121 1.7165 3.4694 1.6697

6722 SRF 2.8012252E-08 2.12734775E-07 1.6756 1.8472 2.3273 2.4036 1.3765 3.0778 2.431779022 TMEM106C transmembrane protein 106C 1.35484921E-05 5.53697267E-05 1.6755 1.3838 1.3815 1.8183 1.4404 1.9385 1.984555033 FKBP14 FK506 binding protein 14, 22 kDa 0.00417827717 0.010038853451 1.6755 2.4998 2.9337 2.0480 2.3504 4.2363 2.86443993 LLGL2 lethal giant larvae homolog 2 (Drosophila) 0.00042188518 0.001265794105 1.6753 0.3463 0.4037 0.5059 0.3307 0.2731 0.530757655 GRAMD1A GRAM domain containing 1A 2.21344996E-05 8.64191402E-05 1.6748 0.9817 1.1241 1.0662 0.9052 1.1524 1.011280304 C2orf44 chromosome 2 open reading frame 44 0.00016392985 0.000536412296 1.6737 1.7110 2.0033 1.5758 1.1574 1.9157 1.469284975 MFSD5 major facilitator superfamily domain containing 5 1.43165512E-09 1.59313047E-08 1.6727 1.9516 1.5751 2.1274 1.4853 1.9797 1.86779967 THRAP3 thyroid hormone receptor associated protein 3 9.42907177E-08 6.28329684E-07 1.6717 1.3899 1.3548 1.3154 1.5484 1.5550 1.422292345 NAF1 nuclear assembly factor 1 ribonucleoprotein 0.00012514745 0.000421199883 1.6712 1.7680 2.0643 1.7243 2.1578 2.9220 2.430951550 CINP cyclin-dependent kinase 2 interacting protein 7.64300149E-09 6.73029216E-08 1.6712 1.1235 0.5130 0.5075 0.4631 0.1849 0.31631318 SLC31A2 solute carrier family 31 (copper transporter), member 2 0.00945441926 0.020592579423 1.6712 1.8142 2.5172 1.2442 1.6871 2.3834 1.18233157 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 7.22337248E-05 0.000255686675 1.6705 0.8904 0.9432 1.0440 0.9207 1.4557 0.999084844 PHF5A PHD finger protein 5A 1.08159446E-06 5.596968E-06 1.6704 2.0894 4.2242 1.8871 1.5849 3.3563 1.1468128869 PIGU phosphatidylinositol glycan anchor biosynthesis, class U 0.00024852961 0.0007859351 1.6701 1.0735 1.1904 1.9300 1.2537 2.0646 2.304910938 EHD1 EH-domain containing 1 1.09152037E-07 7.16388656E-07 1.6690 1.3072 1.3769 1.9566 0.8692 1.3146 1.691584289 ING5 inhibitor of growth family, member 5 6.70965383E-06 2.9252874E-05 1.6684 1.4563 2.1849 1.5415 0.8711 2.9131 2.61036390 SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.99702852E-07 1.23359382E-06 1.6680 2.0201 1.9579 2.1829 2.2632 2.7660 2.54423098 HK1 hexokinase 1 9.60031515E-08 6.38344099E-07 1.6680 0.5669 1.3363 0.8853 0.6956 2.0357 1.0483200014 CC2D1B coiled-coil and C2 domain containing 1B 2.83114963E-08 2.14650481E-07 1.6679 0.7080 1.0470 1.1717 0.8242 1.5634 1.2282283131 NEAT1 trophoblast-derived noncoding RNA 0.00085256419 0.002404762728 1.6673 3.6509 2.2798 2.1627 3.3714 4.9093 3.426754535 CCHCR1 coiled-coil alpha-helical rod protein 1 1.40061043E-05 5.69849782E-05 1.6672 0.3567 0.3503 0.4277 0.4799 0.4537 0.40781070 CETN3 centrin, EF-hand protein, 3 (CDC31 homolog, yeast) 0.00214993174 0.005534557713 1.6670 2.4223 2.7134 2.9156 2.7371 3.5632 3.985055164 SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 2.69015267E-06 1.27379993E-05 1.6669 2.8383 1.6092 2.3967 2.2696 1.6179 2.137223647 ARFIP2 ADP-ribosylation factor interacting protein 2 2.24359195E-08 1.75341797E-07 1.6656 2.4509 3.0155 6.0425 1.1924 1.2140 1.70686118 RPA2 replication protein A2, 32kDa 1.08949285E-08 9.224844E-08 1.6652 1.8082 1.8996 1.5359 1.7361 2.8767 2.059510257 ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 3.53508772E-06 1.63568303E-05 1.6650 0.9462 1.5589 0.9291 0.6595 1.5594 0.821825824 PRDX5 peroxiredoxin 5 4.24277488E-08 3.09106789E-07 1.6649 1.4038 3.6285 2.7515 0.8971 3.6565 3.785810533 ATG7 autophagy related 7 3.8757625E-06 1.77800483E-05 1.6642 2.1817 2.6369 1.6513 1.9804 3.5029 2.173064975 MRPL41 mitochondrial ribosomal protein L41 1.15747139E-06 5.95084898E-06 1.6637 1.7844 1.2083 1.0695 1.2946 1.1313 1.826151202 DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 2.07647845E-08 1.63893798E-07 1.6625 1.2770 0.8703 1.0447 1.4862 1.6833 1.05364043 LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.85571169E-08 2.16333184E-07 1.6622 1.4411 2.8369 1.4917 1.5283 3.7867 1.5946

serum response factor (c-fos serum response element-binding transcription factor)

10528 NOP56 NOP56 ribonucleoprotein 1.58072727E-05 6.36751515E-05 1.6614 1.5181 7.2679 0.7590 0.8130 2.5477 0.733454969 C4orf27 chromosome 4 open reading frame 27 0.00269143811 0.006772890405 1.6613 2.1366 2.0904 1.3061 1.4516 2.0080 1.203191750 LIN52 lin-52 homolog (C. elegans) 0.00206345957 0.00533666431 1.6603 3.0157 4.8251 2.4516 2.4578 2.7683 1.262130001 ERO1L ERO1-like (S. cerevisiae) 1.56808985E-07 9.91766623E-07 1.6601 2.3003 2.1785 1.0725 1.8755 3.8170 2.00046810 STX4 syntaxin 4 4.99313762E-09 4.71009864E-08 1.6588 1.3794 1.8511 1.3586 1.5427 2.2292 1.896927131 SNX5 sorting nexin 5 1.22762914E-07 7.94679154E-07 1.6581 7.3539 2.9882 1.7832 3.9904 3.8284 1.726923361 ZNF629 zinc finger protein 629 0.00030084143 0.000935177726 1.6577 1.9178 2.0241 1.3468 1.5438 1.9119 1.69329989 PPP4R1 protein phosphatase 4, regulatory subunit 1 4.4306087E-07 2.50638025E-06 1.6573 2.4029 2.0824 1.5931 1.9029 2.6752 1.78391508 CTSB cathepsin B 0.00335448547 0.008239435209 1.6567 0.6568 1.1121 0.9066 0.9473 1.4838 1.178651312 SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 5.39960072E-05 0.000195873544 1.6563 0.5343 0.9297 0.7857 0.6417 1.1914 1.01099785 DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 5.68989641E-09 5.2667572E-08 1.6558 0.2685 0.2987 0.5364 0.3265 0.2540 0.43312975 GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 4.39274405E-08 3.18761792E-07 1.6557 2.6368 8.8070 5.4854 0.9985 4.5106 1.153257539 WDR35 WD repeat domain 35 0.00100604409 0.002793259024 1.6549 0.6285 0.7437 0.9168 0.5734 0.7186 0.882965251 ZNF649 zinc finger protein 649 0.00323360706 0.007976472948 1.6546 1.9152 2.1471 1.3103 2.0744 3.6032 2.17983052 HCCS holocytochrome c synthase 3.44059987E-06 1.59681587E-05 1.6537 2.6827 2.0408 2.5296 2.4082 2.5636 2.501265057 ACD adrenocortical dysplasia homolog (mouse) 6.15053837E-06 2.70020752E-05 1.6536 1.4126 0.9074 1.5740 0.8879 2.3700 1.482454859 ELP6 elongator acetyltransferase complex subunit 6 1.1208804E-06 5.77572662E-06 1.6534 1.5807 2.6188 1.9417 1.8547 6.5401 3.8500

57580 PREX1 6.80517449E-05 0.000242055963 1.6531 0.5271 0.7579 0.9046 0.7540 1.2116 1.2215208 AKT2 v-akt murine thymoma viral oncogene homolog 2 1.00291281E-07 6.6347657E-07 1.6530 0.8513 0.7539 0.7694 0.6046 0.8313 0.898529901 SAC3D1 SAC3 domain containing 1 2.77228423E-05 0.000106150833 1.6524 1.8347 1.6556 1.6874 1.8605 1.6664 1.87712653 GCSH glycine cleavage system protein H (aminomethyl carrier) 0.00360534662 0.008787100643 1.6523 1.6843 1.3242 1.5616 1.4045 1.6348 1.58288520 HAT1 histone acetyltransferase 1 3.65592983E-06 1.68689772E-05 1.6519 1.7580 1.5110 1.9087 2.0661 1.9239 2.22695606 MAP2K3 mitogen-activated protein kinase kinase 3 2.21674126E-07 1.35059341E-06 1.6512 1.1989 1.9984 1.4788 0.9931 2.3386 1.66136949 TCOF1 Treacher Collins-Franceschetti syndrome 1 5.87690591E-05 0.000211466768 1.6508 0.9693 0.8305 1.1269 0.7688 0.7861 0.999984934 C12orf52 chromosome 12 open reading frame 52 3.22578575E-08 2.4047963E-07 1.6496 0.5233 1.3494 2.1076 0.1096 0.5683 1.40803396 ICT1 immature colon carcinoma transcript 1 4.11214165E-07 2.34071814E-06 1.6488 1.4790 3.1639 1.6635 1.2694 4.5010 1.743726063 DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 0.00355057213 0.008667475478 1.6488 0.7071 2.0468 0.8488 0.5883 2.1261 1.176480273 GRPEL1 GrpE-like 1, mitochondrial (E. coli) 3.46658036E-06 1.60805677E-05 1.6481 1.5919 3.1457 3.6778 1.2031 3.8365 4.051554811 ZNF562 zinc finger protein 562 0.00020507495 0.000657852777 1.6469 1.1431 1.9930 0.9516 1.9292 3.1172 1.671684240 ZCCHC9 zinc finger, CCHC domain containing 9 5.82723859E-05 0.000209927649 1.6468 3.3407 1.2336 1.1790 1.1677 0.3076 1.09491487 CTBP1 C-terminal binding protein 1 1.50910528E-07 9.58441838E-07 1.6466 6.3164 0.5536 0.7058 10.8105 0.8153 1.34958864 PER2 period circadian clock 2 0.00032370645 0.000999115575 1.6461 0.6179 0.9700 0.9619 0.6266 0.8295 0.973179415 C17orf62 chromosome 17 open reading frame 62 1.61784794E-05 6.50127942E-05 1.6460 0.8112 2.1650 1.0286 0.7448 1.6820 1.1054154467 CCDC167 chromosome 6 open reading frame 129 3.44306557E-06 1.59755445E-05 1.6458 2.4125 1.9413 1.5269 2.2716 2.5488 1.3500353 APRT adenine phosphoribosyltransferase 1.44532293E-07 9.21456407E-07 1.6455 1.9011 3.5641 1.8698 1.4887 3.3557 2.806164682 ANAPC1 anaphase promoting complex subunit 1 2.22388323E-08 1.74099376E-07 1.6450 2.3189 3.3135 1.8250 2.5792 5.0207 3.016379140 CCDC28B coiled-coil domain containing 28B 5.1927507E-05 0.000188744661 1.6444 1.7795 3.0079 2.2235 1.6648 2.8639 1.79048525 DGKZ diacylglycerol kinase, zeta 8.93781951E-08 5.99529509E-07 1.6441 2.7553 2.1254 2.2703 1.8899 1.5150 1.80255355 PLP2 proteolipid protein 2 (colonic epithelium-enriched) 3.097307E-06 1.44852812E-05 1.6439 0.8695 1.0221 1.4291 0.7945 1.4096 1.687064960 MRPS15 mitochondrial ribosomal protein S15 4.2099348E-08 3.06836572E-07 1.6422 2.1677 3.3618 2.0683 2.0030 3.4766 2.0976128486 FITM2 fat storage-inducing transmembrane protein 2 0.01012814154 0.021869477755 1.6422 1.5121 2.0850 2.2052 0.9478 1.8398 2.173980196 RNF34 ring finger protein 34, E3 ubiquitin protein ligase 1.1902818E-09 1.36356295E-08 1.6417 2.6909 1.5721 1.8667 2.4661 3.0709 2.873064963 MRPS11 mitochondrial ribosomal protein S11 1.30745179E-07 8.40301058E-07 1.6407 7.4177 0.1854 3.0096 5.6622 0.1944 1.4103314 AOC2 amine oxidase, copper containing 2 (retina-specific) 0.00525984593 0.012297876496 1.6401 0.0741 0.0890 0.2070 0.1242 0.0765 0.203522856 CHSY1 carbohydrate (chondroitin) synthase 1 5.05140991E-06 2.26223926E-05 1.6400 1.0987 2.0682 1.4985 0.9542 1.5326 1.42376618 SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 1.39241762E-08 1.15019235E-07 1.6389 1.5177 2.2187 2.1666 1.0298 2.8715 1.97233054 HCFC1 host cell factor C1 (VP16-accessory protein) 3.97397972E-06 1.81622205E-05 1.6388 0.9280 3.5638 2.5401 1.3987 9.3790 8.05876929 TCF3 transcription factor 3 9.87065452E-07 5.14276018E-06 1.6380 0.4576 0.6557 0.7852 0.3867 0.6345 0.833491272 BOD1 family with sequence similarity 44, member B 0.00053406619 0.001568379539 1.6368 1.3141 1.8175 1.5044 1.0700 2.0038 1.3671151648 SGOL1 shugoshin-like 1 (S. pombe) 0.012337267 0.025956790417 1.6364 2.9559 2.5404 1.9281 2.4678 2.8540 2.510510617 STAMBP STAM binding protein 3.77440507E-06 1.73411942E-05 1.6363 2.4161 1.8159 2.2306 2.0460 2.1956 2.356225911 DPCD deleted in primary ciliary dyskinesia homolog (mouse) 0.02512443523 0.048050416632 1.6362 0.3645 1.1326 0.2481 0.4526 1.3253 0.06342802 GOLGA3 golgin A3 9.41790766E-08 6.27814698E-07 1.6361 1.3502 2.4904 1.4676 1.1764 2.6253 1.94327357 UGCG UDP-glucose ceramide glucosyltransferase 0.00039372669 0.001191680306 1.6359 2.3173 2.2521 1.5544 2.0797 4.1205 2.651184650 EBPL emopamil binding protein-like 1.1673735E-06 5.99838261E-06 1.6356 2.1349 1.9840 1.9252 1.5384 1.6884 1.994957407 NMRAL1 NmrA-like family domain containing 1 1.01787885E-07 6.71432576E-07 1.6355 0.2201 0.8427 0.6405 0.1071 0.2010 0.504593343 MVB12A multivesicular body subunit 12A 3.10884009E-07 1.82828214E-06 1.6352 1.5481 1.5482 1.8898 1.5046 2.0119 2.19495129 CDK18 cyclin-dependent kinase 18 0.02522448612 0.048212367196 1.6348 0.7080 1.5466 0.7572 0.5219 1.4731 0.576454885 TBC1D8B TBC1 domain family, member 8B (with GRAM domain) 0.01757038952 0.035287553013 1.6348 1.2164 2.5157 1.0161 1.0066 2.7227 0.904384915 FAM222A family with sequence similarity 222, member A 0.01883201394 0.037479934972 1.6345 0.8641 1.3376 0.9646 0.6794 0.7125 0.97606050 RNH1 ribonuclease/angiogenin inhibitor 1 1.82934654E-07 1.13925767E-06 1.6342 1.1041 2.0901 1.6028 0.8397 1.9531 1.911084908 FAM136A family with sequence similarity 136, member A 3.52551189E-07 2.04567016E-06 1.6323 1.2997 1.6465 1.4472 1.0531 2.5831 1.890054752 FNDC8 fibronectin type III domain containing 8 0.00941464538 0.020518177537 1.6316 0.3289 0.0805 0.3156 0.4309 0.2081 1.015084922 FIZ1 FLT3-interacting zinc finger 1 5.53881368E-06 2.46001953E-05 1.6311 0.3681 1.1943 1.1749 0.3131 0.6088 0.683681544 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 0.00091514809 0.002565447365 1.6302 0.3498 0.5229 0.5433 0.3576 0.5252 0.5928196743 PAOX polyamine oxidase (exo-N4-amino) 0.00236964575 0.00603795386 1.6302 1.8257 2.5500 1.2983 1.3555 1.9761 1.7693411 ARSB arylsulfatase B 0.00011898803 0.000402247783 1.6297 1.0427 0.9576 1.2130 0.8182 0.7036 1.37719937 DCLRE1A DNA cross-link repair 1A 0.0005010047 0.001478894646 1.6291 0.7572 1.1579 1.6997 0.3142 0.5135 0.681757602 USP36 ubiquitin specific peptidase 36 1.91369153E-08 1.52228871E-07 1.6290 0.6612 0.5567 0.8673 0.6345 0.5439 0.93825781 PTPN11 protein tyrosine phosphatase, non-receptor type 11 8.61046123E-08 5.80769094E-07 1.6289 1.8572 2.1334 1.4337 2.0522 2.9715 2.438664745 METTL17 methyltransferase like 17 5.85596144E-08 4.10433937E-07 1.6279 2.1092 2.5401 1.1554 1.8419 4.0956 1.8306154807 VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 0.00354024501 0.008644575281 1.6267 1.5427 1.4549 1.5932 1.2115 1.6439 2.0118113026 PLCD3 phospholipase C, delta 3 0.00445071353 0.010609711356 1.6266 0.3206 0.8075 0.7661 0.3941 0.8986 0.532222868 FASTKD2 FAST kinase domains 2 1.20384888E-06 6.16673023E-06 1.6262 0.6639 1.8294 1.1719 0.3922 2.0258 0.626490580 C19orf52 chromosome 19 open reading frame 52 5.5136214E-06 2.44980029E-05 1.6259 0.5573 9.7425 1.7663 0.1919 3.2619 2.809129902 FAM216A family with sequence similarity 216, member A 6.27690598E-05 0.000224841455 1.6258 0.3321 0.3321 0.3321 0.3970 0.3970 0.39709780 PIEZO1 piezo-type mechanosensitive ion channel component 1 8.79406034E-07 4.6333642E-06 1.6258 0.5111 1.9000 0.5159 0.4337 1.1405 0.784856882 CDC42SE1 CDC42 small effector 1 7.23689199E-07 3.8960663E-06 1.6257 7.4820 6.6811 1.3757 2.7396 2.7337 0.12209939 RBM8A RNA binding motif protein 8A 8.35271491E-07 4.42764163E-06 1.6256 2.4759 4.2175 2.2915 2.3927 7.1042 2.662156852 RAD18 RAD18 homolog (S. cerevisiae) 0.00012698941 0.000427005977 1.6253 2.5012 2.6680 1.7170 2.1381 3.1012 1.9119375690 WASH5P CXYorf1-related protein 0.00380998365 0.009226775521 1.6247 1.8043 1.6966 1.8133 2.0392 2.2032 2.46991729 DIAPH1 diaphanous-related formin 1 1.17817808E-07 7.66654912E-07 1.6237 0.7151 0.5654 0.5507 0.8777 0.7169 0.662910603 SH2B2 SH2B adaptor protein 2 0.02254090973 0.04372730678 1.6233 0.5581 0.9082 1.5975 0.3533 0.5913 0.74515966 REL v-rel avian reticuloendotheliosis viral oncogene homolog 2.76065303E-05 0.000105749795 1.6219 2.7328 1.6059 0.8709 2.9096 6.4679 2.0632345757 FAM174A family with sequence similarity 174, member A 0.00261611146 0.006603341415 1.6198 2.1685 2.5156 1.4305 2.0553 2.8662 1.581084619 ZGPAT zinc finger, CCCH-type with G patch domain 4.97232564E-08 3.55177225E-07 1.6190 0.4132 1.6964 1.3970 0.2199 2.0877 0.60068079 MLF2 myeloid leukemia factor 2 2.16380353E-07 1.3220322E-06 1.6183 1.1290 2.5626 2.3719 0.9822 2.6070 1.976483549 UCK1 uridine-cytidine kinase 1 1.70716001E-07 1.07082828E-06 1.6175 1.2437 1.4323 1.8645 0.8818 1.3166 2.089423456 ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 2.06983716E-06 1.00692398E-05 1.6170 2.4332 1.9584 1.6721 2.5104 3.0440 2.2507

55343 SLC35C1 2.06674892E-07 1.27193116E-06 1.6166 1.0469 1.7602 1.8156 0.6948 2.0798 2.04795498 PPOX protoporphyrinogen oxidase 0.00126786664 0.003447389776 1.6159 1.5288 2.4388 2.4800 1.1339 2.7171 3.327423633 KPNA6 karyopherin alpha 6 (importin alpha 7) 1.05313707E-08 8.93357496E-08 1.6155 1.2568 1.3719 0.9732 1.4030 1.5148 1.181827034 ACAD8 acyl-CoA dehydrogenase family, member 8 6.36914545E-05 0.00022774369 1.6154 0.5938 0.2897 1.0790 0.2507 1.3227 0.3104541578 CXorf40B chromosome X open reading frame 40B 6.76974197E-06 2.94867045E-05 1.6147 2.4923 6.1483 0.9439 1.0927 5.8212 0.640284304 NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 7.59138225E-09 6.69448535E-08 1.6125 1.2596 1.8447 2.1245 0.6913 1.1121 1.07668729 GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 4.36905781E-08 3.17654028E-07 1.6107 2.6495 1.6787 1.7013 2.1788 2.4380 2.337711198 SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 2.47613019E-07 1.48926434E-06 1.6105 2.3667 2.5200 2.1737 2.4409 3.8802 3.337089927 C16orf45 chromosome 16 open reading frame 45 0.00489713019 0.011554798929 1.6102 0.4202 1.1534 0.6860 0.3982 1.0971 0.71381399 CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 9.00372283E-08 6.03285748E-07 1.6102 1.7967 1.6945 1.6077 1.8851 3.6514 2.695385019 TMEM241 transmembrane protein 241 0.0047719352 0.011294404144 1.6099 0.8910 1.0066 0.8709 0.7998 1.4891 0.770881502 HM13 histocompatibility (minor) 13 1.59030884E-07 1.00477604E-06 1.6091 1.7207 1.2602 1.7521 1.6087 2.0739 2.376226523 AGO1 argonaute RISC catalytic component 1 6.07244906E-09 5.55890728E-08 1.6091 0.5932 0.7571 0.5897 0.5621 0.4788 0.6058120425 AMICA1 adhesion molecule, interacts with CXADR antigen 1 0.00128736543 0.003494168315 1.6089 1.3271 1.6923 1.9854 1.1727 1.8525 1.34055538 PPT1 palmitoyl-protein thioesterase 1 6.31256672E-06 2.76668791E-05 1.6085 1.0033 1.7842 0.8487 0.9569 1.4250 0.92429600 PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 3.57163061E-07 2.06914504E-06 1.6081 0.5804 1.4214 1.3098 0.6437 1.8283 1.39576525 SMTN smoothelin 0.00098933227 0.002751039302 1.6077 0.5308 0.6590 0.8540 0.4472 0.8536 0.804129928 TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 9.28160146E-08 6.19632524E-07 1.6076 1.6286 1.0107 1.6251 1.3232 1.4362 2.273423101 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 0.01511125554 0.0309647708 1.6073 0.2744 0.4242 0.5533 0.3187 0.3662 0.628122888 UBOX5 U-box domain containing 5 1.73229299E-05 6.91408966E-05 1.6068 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970138199 C9orf41 chromosome 9 open reading frame 41 0.00020024369 0.000643937458 1.6061 2.2788 1.8011 1.5582 1.9790 2.3601 3.00809138 ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 1.53575606E-06 7.69225185E-06 1.6057 1.5128 1.0751 1.5314 1.3982 1.4960 1.58443073 HEXA hexosaminidase A (alpha polypeptide) 2.01341558E-06 9.81828918E-06 1.6057 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970145438 FRMD6-AS1 FRMD6 antisense RNA 1 0.0060717955 0.013941172071 1.6055 1.8866 8.1779 0.7452 1.3673 4.0459 0.406279856 SNX22 sorting nexin 22 0.00683106981 0.015476417543 1.6049 1.4701 1.8923 1.4736 0.7866 2.0767 1.69359801 MRPL19 mitochondrial ribosomal protein L19 1.07472292E-07 7.06379035E-07 1.6047 1.3981 1.6909 1.5166 1.3521 2.7381 2.51981263 PLK3 polo-like kinase 3 0.00015916112 0.000523056125 1.6046 1.2893 1.9700 2.1830 1.3322 2.1279 2.74208448 DOC2A double C2-like domains, alpha 0.00519834608 0.012175897896 1.6042 0.2753 0.8435 0.5817 0.2750 0.4217 0.53289601 PDIA4 protein disulfide isomerase family A, member 4 6.48109256E-05 0.000231429594 1.6042 1.6763 2.3255 1.8503 1.1137 2.8661 2.91122130 EWSR1 EWS RNA-binding protein 1 2.45137873E-07 1.47778265E-06 1.6039 0.6734 1.6379 0.4222 1.0973 2.2646 1.004355571 CNOT11 chromosome 2 open reading frame 29 2.37860355E-09 2.46103307E-08 1.6019 2.6088 1.5110 2.0530 2.2749 2.0873 2.774179706 PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0047941416 0.011342555397 1.6015 1.2252 1.0392 0.9101 1.0435 0.7323 0.928755090 MED9 mediator complex subunit 9 9.46345555E-05 0.000326812058 1.6009 1.9322 2.1935 1.4531 1.5302 4.0205 1.3437619499 SNORA27 small nucleolar RNA, H/ACA box 27 0.00034254519 0.001051047145 1.6005 0.3058 0.5727 0.5422 0.7381 0.6582 0.37577469 NELFA negative elongation factor complex member A 2.28143956E-09 2.36854907E-08 1.6002 0.9776 0.6780 0.5595 0.8692 1.0857 0.935155051 NRDE2 NRDE-2, necessary for RNA interference, domain containing 0.00013786004 0.000459667642 1.5999 1.0023 1.2582 0.8700 1.1909 1.4904 1.060010128 LRPPRC leucine-rich pentatricopeptide repeat containing 1.36234449E-06 6.90698073E-06 1.5996 2.1366 2.0574 2.1676 2.6750 4.1879 2.768727153 ZNF777 zinc finger protein 777 6.83370108E-08 4.72438086E-07 1.5996 1.2760 4.1567 1.5287 1.5465 2.8166 1.643884336 TMEM101 transmembrane protein 101 2.89537394E-08 2.18974638E-07 1.5985 2.6844 1.2779 1.4157 2.2334 1.5409 1.7740146923 RUNDC1 RUN domain containing 1 1.52367053E-06 7.6338108E-06 1.5984 3.2973 1.7854 4.6302 1.9562 2.5684 1.28647317 UBA1 ubiquitin-like modifier activating enzyme 1 2.62178609E-07 1.5696355E-06 1.5977 1.4709 1.3877 1.1787 1.3686 1.7052 1.5300146059 CDAN1 congenital dyserythropoietic anemia, type I 0.00021737287 0.000693891863 1.5968 0.4425 0.7406 0.7197 0.5220 0.9911 0.742724145 PANX1 pannexin 1 4.7651222E-05 0.000174555559 1.5967 2.1940 3.2072 2.5137 1.9478 3.4687 3.6577165186 FAM179A similar to RIKEN cDNA 4632412N22 gene 0.02247255723 0.04362713193 1.5958 0.6320 1.0944 1.0668 0.3727 0.4297 0.7113

123879 DCUN1D3 0.00173486042 0.004562373276 1.5952 0.3321 0.3321 0.3321 0.3970 0.3970 0.397081576 CCDC130 coiled-coil domain containing 130 1.38229125E-05 5.63525785E-05 1.5950 2.1677 2.1753 2.0548 1.6726 3.1540 1.940926263 FBXO22 F-box protein 22 1.88760009E-05 7.47836704E-05 1.5942 1.5536 1.6759 1.4753 1.5477 2.4640 2.1535661 POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 8.31781106E-08 5.63108721E-07 1.5924 0.7723 1.3550 3.4539 0.9148 0.5956 4.17217942 TFEB transcription factor EB 0.00033776068 0.001037935274 1.5919 0.3758 0.5914 0.7203 0.3302 0.4054 0.586823150 FRMD4B FERM domain containing 4B 0.00031841058 0.00098409982 1.5908 0.8798 1.0255 0.9588 0.7880 0.6808 0.88453104 ZBTB48 zinc finger and BTB domain containing 48 0.00010290908 0.000352853217 1.5908 0.6935 1.3214 1.0813 0.5529 1.1798 0.896764777 RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 4.92215735E-07 2.74451202E-06 1.5901 0.7443 0.9972 0.7510 0.6558 0.7373 0.9577

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

Q96A29,B3KQH0,solute carrier family 35 (GDP-fucose transporter), member C1

DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)

593 BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 3.34901868E-07 1.95380809E-06 1.5901 1.6375 2.3743 1.4267 1.0604 1.3489 1.159510171 RCL1 RNA terminal phosphate cyclase-like 1 2.15265527E-06 1.04221826E-05 1.5898 1.3346 1.1717 1.6037 1.0139 1.1609 1.5486

50485 SMARCAL1 8.69395131E-08 5.85320112E-07 1.5894 0.7938 0.7854 0.7083 1.0269 0.7616 0.97491870 E2F2 E2F transcription factor 3 0.01935722314 0.038359704678 1.5894 1.3255 1.6935 2.7145 0.8993 0.9584 2.610551097 SCCPDH saccharopine dehydrogenase (putative) 9.37441995E-06 3.96136451E-05 1.5886 2.2337 1.1526 2.0663 1.9470 1.4431 2.349579939 SLC35E1 solute carrier family 35, member E1 4.7634992E-09 4.52898114E-08 1.5885 3.0153 3.1813 2.3620 2.5275 5.0010 3.2613112611 RWDD2A RWD domain containing 2A 0.00806014538 0.017892719756 1.5879 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970952 CD38 CD38 molecule 0.00291852787 0.007279189347 1.5866 1.5149 1.8928 1.6198 1.5252 2.2609 1.794754187 NANS N-acetylneuraminic acid synthase 1.07711759E-06 5.57538034E-06 1.5864 0.8217 1.3289 1.0134 0.7850 1.4583 1.187783606 GUCD1 guanylyl cyclase domain containing 1 2.18700273E-07 1.3351458E-06 1.5860 3.0626 3.0147 2.7528 1.5450 4.6840 2.863484193 SETD3 SET domain containing 3 3.54460587E-09 3.49525302E-08 1.5860 2.5561 3.1874 2.3566 1.2806 2.7013 1.94129537 TP53I11 tumor protein p53 inducible protein 11 0.0006154674 0.001782504404 1.5859 1.1520 1.0609 1.1868 1.0577 0.9330 1.29294047 LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 2.6902331E-06 1.27379993E-05 1.5855 2.1027 0.9491 2.1945 1.3207 0.5957 1.8173125988 C19orf70 hypothetical protein P117 2.09862523E-08 1.65356103E-07 1.5854 3.2829 0.2385 1.1122 0.5980 0.3008 2.972260491 NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 0.00019609216 0.000631643231 1.5853 0.4884 0.5654 1.2891 0.5419 0.3781 0.74332634 GBP2 guanylate binding protein 2, interferon-inducible 7.3878229E-07 3.96330887E-06 1.5843 2.3468 1.3696 1.2724 1.9368 1.5928 1.440223475 QPRT quinolinate phosphoribosyltransferase 0.00491862261 0.011593533578 1.5843 0.7765 0.9208 1.4251 0.2954 0.5926 0.811954552 GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 1.71144588E-08 1.37578263E-07 1.5842 1.4342 2.6555 2.1410 2.0073 3.4082 3.7556348327 ZNF530 zinc finger protein 530 0.00964207855 0.020938918376 1.5841 1.7427 2.4231 1.3359 1.7658 3.3432 1.2886113235 SLC46A1 solute carrier family 46 (folate transporter), member 1 0.00557830202 0.012939791103 1.5840 1.6308 1.0076 1.6985 1.4901 1.4612 1.38855891 MOK MOK protein kinase 0.00983021127 0.021312010014 1.5836 1.0958 0.8519 0.8293 1.3343 1.2784 0.885556910 STARD7 StAR-related lipid transfer (START) domain containing 7 4.14669674E-07 2.35891099E-06 1.5833 1.0578 0.7937 1.7092 0.5174 0.9935 0.827223221 RHOBTB2 Rho-related BTB domain containing 2 0.00032455751 0.001001573185 1.5831 0.7034 0.8220 0.6710 0.8347 0.7544 0.818528987 NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 6.60042765E-07 3.5797867E-06 1.5831 1.5011 1.9542 1.6099 1.5498 3.3562 1.81565393 EXOSC9 exosome component 9 1.65998431E-05 6.66181272E-05 1.5808 2.3040 1.5672 1.0176 2.2203 1.8751 1.106555278 QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 2.31072684E-05 8.9814084E-05 1.5801 0.3321 0.3321 0.3321 0.3970 0.3970 0.397056339 METTL3 methyltransferase like 3 2.79818458E-06 1.32114803E-05 1.5799 1.1374 1.3273 1.2289 1.2319 2.0905 1.5783654321 SNORA75 small nucleolar RNA, H/ACA box 75 0.02579462552 0.049141841043 1.5790 0.3240 0.3852 0.4358 0.1059 0.0892 0.3687134728 IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1 0.00713843723 0.016062461751 1.5785 0.9767 1.0986 0.9263 0.8724 0.9544 1.364726958 COPG2 coatomer protein complex, subunit gamma 2 0.00213391453 0.005500971547 1.5769 1.3995 1.9969 1.9162 1.0069 2.2542 2.2602126917 IFFO2 intermediate filament family orphan 2 1.25780346E-05 5.17043529E-05 1.5767 1.9789 2.2077 2.2699 1.4639 2.2390 2.980484065 TMEM222 transmembrane protein 222 1.36565819E-06 6.91802229E-06 1.5767 1.5926 1.7640 1.7048 1.5610 2.5323 2.57094331 MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0013466658 0.003636753995 1.5760 2.1906 3.0938 1.6022 2.4641 3.5264 1.71519261 MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.55282197E-05 9.82831079E-05 1.5735 1.8072 1.1664 1.8855 1.7947 1.2471 2.362423294 ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 6.73188798E-06 2.93358114E-05 1.5734 0.7097 0.8805 0.6678 0.6699 1.4500 1.059930849 PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 2.23422449E-08 1.74759203E-07 1.5734 1.9980 3.6234 1.7599 1.7399 4.0412 1.64519546 APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 5.59706664E-07 3.08319571E-06 1.5730 1.2212 0.7655 1.7628 1.3874 1.1533 2.082757799 RAB40C RAB40C, member RAS oncogene family 0.00012507454 0.000421046852 1.5720 1.2922 1.4704 1.4630 1.4474 3.0793 2.768379959 CEP76 centrosomal protein 76kDa 0.00269012133 0.006771441925 1.5718 1.4868 1.9521 2.0368 1.3038 1.1138 1.850651434 ANAPC7 anaphase promoting complex subunit 7 3.30894711E-08 2.46277318E-07 1.5703 2.3165 1.7842 1.8131 1.9687 2.3899 2.199329115 SAP30BP SAP30 binding protein 1.34613483E-08 1.11498529E-07 1.5701 0.3335 28.0369 0.7144 0.1051 12.5386 0.476363925 ZNF335 zinc finger protein 335 8.20155443E-09 7.16000012E-08 1.5686 0.7947 1.0452 0.8469 0.6021 0.8110 0.9307890 CCNA2 cyclin A2 0.00796981294 0.017718021897 1.5685 2.7226 2.9557 1.0792 1.8405 3.0134 2.1393379 ARL4D ADP-ribosylation factor-like 4D 0.00624426377 0.014286900523 1.5682 3.2469 2.1069 1.3770 2.2883 2.0961 1.4168642846 LOC642846 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11-like 0.00052622779 0.001547350202 1.5678 1.2166 0.8022 0.5016 1.1669 0.8878 0.686451079 NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 7.02046251E-08 4.84250249E-07 1.5659 0.3321 0.3321 0.3321 0.3970 0.3970 0.397056940 DUSP22 dual specificity phosphatase 22 1.41314816E-06 7.12894621E-06 1.5657 0.6348 1.2317 0.8783 0.6269 1.0774 1.08788723 SNX4 sorting nexin 4 1.07184601E-06 5.55559414E-06 1.5648 1.7942 1.9883 1.8909 1.5247 3.1755 1.99755977 DPF2 D4, zinc and double PHD fingers family 2 1.85008452E-08 1.47683462E-07 1.5648 2.1204 1.8554 1.5722 3.0170 2.8174 2.5420617 BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 3.86355471E-05 0.000144242044 1.5647 0.4434 1.8744 0.7743 0.1647 0.3894 0.44368994 LIMD1 LIM domains containing 1 6.68931454E-06 2.91792644E-05 1.5646 1.9163 2.5268 2.0846 1.9829 2.0693 1.78176729 SRP54 signal recognition particle 54kDa 5.85137682E-09 5.37538246E-08 1.5646 2.5221 4.1989 1.9890 2.5531 8.0930 3.24835601 MAPK9 mitogen-activated protein kinase 9 1.07249367E-06 5.55563441E-06 1.5632 0.7192 1.5510 1.0122 0.9335 1.6892 1.424855640 FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 0.00597411511 0.013743090921 1.5631 0.7981 0.8894 0.8622 0.5520 0.7593 0.815579175 ZNF343 zinc finger protein 343 0.00291502583 0.007272440181 1.5624 1.1001 1.2678 1.1767 1.1401 1.3638 1.72177343 UBTF upstream binding transcription factor, RNA polymerase I 4.94812239E-07 2.75814803E-06 1.5619 1.6216 3.4108 1.9886 1.3291 3.7377 2.441223066 CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.00591600426 0.013624556327 1.5615 1.6958 1.3683 1.1578 1.6111 0.8735 1.33537265 TTC1 tetratricopeptide repeat domain 1 1.10722063E-08 9.3556709E-08 1.5614 1.9603 2.5769 2.0179 2.2587 2.8801 2.33119404 LPXN leupaxin 6.57602962E-07 3.5686728E-06 1.5601 3.6594 5.6128 2.0401 3.4769 5.8326 1.987784981 MIR22HG MIR22 host gene (non-protein coding) 0.00532180743 0.01242049628 1.5599 0.3815 16.4687 1.6284 0.2314 17.4052 1.561184923 FAM104A family with sequence similarity 104, member A 1.20480356E-06 6.1698909E-06 1.5588 0.3321 0.3321 0.3321 0.3970 0.3970 0.397010330 CNPY2 canopy FGF signaling regulator 2 1.54878432E-08 1.26055176E-07 1.5586 2.0938 1.7845 1.5036 1.9865 3.6667 2.296292305 TMEM129 transmembrane protein 129 8.79917727E-06 3.7416469E-05 1.5573 1.3155 2.1045 1.8003 0.9608 3.7870 2.206479680 C22orf29 chromosome 22 open reading frame 29 9.63215363E-07 5.02965429E-06 1.5573 0.7350 1.2057 2.8463 0.7576 1.3443 4.27538886 DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 7.88768879E-08 5.37374533E-07 1.5567 1.6009 2.8168 1.3621 1.8444 3.7594 2.22893955 LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.00036899686 0.001122210137 1.5565 0.9371 1.6267 1.3584 0.7286 1.1677 1.069225983 NGDN neuroguidin, EIF4E binding protein 5.59684705E-06 2.48338002E-05 1.5560 1.5806 2.0173 2.1071 1.8360 2.3022 2.600726015 RPAP1 RNA polymerase II associated protein 1 1.22043033E-07 7.90769607E-07 1.5554 1.0614 0.8578 0.8136 1.0726 1.1278 0.880255020 TTC38 tetratricopeptide repeat domain 38 0.00036075189 0.001099526032 1.5547 1.3639 0.9168 1.5323 1.1391 1.1776 1.47135033 P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.00034761145 0.001064447193 1.5543 0.7438 1.5715 0.8688 0.6718 2.1833 1.331311234 HPS5 Hermansky-Pudlak syndrome 5 3.77202677E-06 1.73357339E-05 1.5543 1.5961 1.1491 0.4884 0.6235 0.6616 0.23548744 TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.01656678094 0.033503953657 1.5540 0.8829 1.6245 1.9570 0.2875 1.8064 1.41104357 MPST mercaptopyruvate sulfurtransferase 0.00132053992 0.003574652654 1.5536 0.3321 0.3321 0.3321 0.3970 0.3970 0.39703134 HLA-F major histocompatibility complex, class I, F 2.48570029E-06 1.18897162E-05 1.5531 0.6014 0.5929 0.5533 0.7180 0.8598 0.717426151 NAT9 N-acetyltransferase 9 (GCN5-related, putative) 5.56794461E-07 3.07024285E-06 1.5531 5.5862 2.0053 1.5722 3.2117 2.6699 1.2838400566 C17orf97 hypothetical gene supported by AK128660 0.01913700019 0.037982974961 1.5521 1.2501 1.1500 2.2639 0.9093 1.4414 1.29609793 CKAP5 cytoskeleton associated protein 5 1.59130239E-07 1.00505625E-06 1.5517 0.3183 0.9187 1.3246 0.1897 0.2399 1.609325813 SAMM50 SAMM50 sorting and assembly machinery component 1.74281414E-08 1.39976703E-07 1.5511 1.1520 1.1309 1.1114 1.0959 1.4757 1.6679643314 KIAA0754 KIAA0754 0.00381494821 0.009236350036 1.5501 1.5239 2.7531 1.1264 1.2786 1.9587 1.063223557 SNAPIN SNAP-associated protein 1.56023594E-06 7.80844458E-06 1.5496 0.9755 1.5071 1.2015 0.9525 2.0349 1.611011334 TUSC2 tumor suppressor candidate 2 2.38570746E-06 1.14413771E-05 1.5469 1.3817 1.1301 1.5363 0.9861 1.2971 1.448122894 DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 2.32813024E-08 1.81096619E-07 1.5463 1.3172 0.5773 1.2599 0.4479 0.7910 0.384423386 NUDCD3 NudC domain containing 3 4.85782322E-08 3.47814051E-07 1.5460 1.2773 1.5156 0.7833 1.1382 1.7141 1.20598682 PEA15 phosphoprotein enriched in astrocytes 15 4.28867255E-06 1.94496463E-05 1.5457 1.4399 1.9981 2.0941 1.1400 1.8134 1.754955172 DNAAF2 dynein, axonemal, assembly factor 2 1.67159126E-05 6.70544796E-05 1.5449 1.7170 1.8948 1.7509 2.1004 2.0452 3.22419274 BCL7C B-cell CLL/lymphoma 7C 3.64296512E-07 2.10913367E-06 1.5446 0.1204 2.2804 0.7363 0.0651 0.2116 0.2952

6875 TAF4B 7.87354187E-07 4.19741546E-06 1.5430 1.7244 1.9628 1.3582 1.8602 2.0197 2.0463

5050 PAFAH1B3 2.53106958E-07 1.51980622E-06 1.5393 1.1079 0.8068 0.8139 0.2798 0.6552 0.53942182 ACSL4 acyl-CoA synthetase long-chain family member 4 7.50256461E-06 3.24082413E-05 1.5391 2.1644 2.3100 1.4131 2.0268 2.3905 1.930992399 MRRF mitochondrial ribosome recycling factor 1.5950514E-07 1.00707599E-06 1.5390 0.6320 2.8945 0.9434 0.4318 1.1022 0.658451258 MRPL51 mitochondrial ribosomal protein L51 2.56121285E-07 1.53538324E-06 1.5390 2.4224 2.4786 3.0283 2.7388 4.7146 2.777051008 ASCC1 activating signal cointegrator 1 complex subunit 1 1.37472859E-05 5.60567749E-05 1.5378 1.1826 1.0296 1.1338 0.9783 0.8679 0.81288841 HDAC3 histone deacetylase 3 9.8517426E-09 8.41173088E-08 1.5372 1.0748 1.9584 1.4742 0.7828 0.8759 0.866726205 GMEB2 glucocorticoid modulatory element binding protein 2 2.88170342E-06 1.35637519E-05 1.5371 0.3771 0.8281 0.6700 0.5974 1.3003 0.997185406 DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14 3.60663146E-08 2.66049132E-07 1.5369 1.6176 1.8095 1.8900 1.5375 2.7462 2.04364809 NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 8.78105576E-07 4.62918208E-06 1.5362 3.2406 2.3462 1.8704 2.7837 3.5500 3.0363115416 MALSU1 mitochondrial assembly of ribosomal large subunit 1 2.64726156E-06 1.25605721E-05 1.5361 2.1890 2.9557 1.4687 2.3303 4.3388 2.193355832 CAND1 cullin-associated and neddylation-dissociated 1 3.19961505E-07 1.87683359E-06 1.5358 1.1360 1.5284 0.8005 1.1168 2.0464 1.61078178 ELL elongation factor RNA polymerase II 1.5240197E-08 1.24260991E-07 1.5358 0.8467 1.1592 1.2698 0.7149 1.4427 1.6344386724 AMIGO3 adhesion molecule with Ig-like domain 3 0.00329637465 0.008110874991 1.5353 0.9760 1.8403 1.7347 0.7991 1.4130 1.447351693 TRAPPC2L trafficking protein particle complex 2-like 2.2059919E-06 1.06578223E-05 1.5339 0.9059 0.6420 1.2132 0.4719 0.8432 0.362890784 LOC90784 uncharacterized LOC90784 0.00226321576 0.005790181787 1.5331 0.0321 0.3432 0.1304 0.1615 0.0975 0.216654758 KLHDC4 kelch domain containing 4 5.41406192E-06 2.41047123E-05 1.5326 0.6132 0.9467 0.6710 0.6145 1.3208 0.730551522 TMEM14C transmembrane protein 14C 1.80584325E-06 8.91447806E-06 1.5326 1.5839 2.0251 2.1592 1.2131 1.9244 1.97691314 COPA coatomer protein complex, subunit alpha 9.10373114E-07 4.77998205E-06 1.5325 1.1070 2.9951 1.1308 0.7593 5.8561 1.05164048 LTA4H leukotriene A4 hydrolase 0.00014820063 0.000489855635 1.5320 0.6795 0.6454 0.6719 1.0845 0.9902 0.82065871 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 4.65340511E-08 3.346203E-07 1.5312 2.5482 2.4922 1.9750 1.9413 2.0575 2.223254896 PQLC2 PQ loop repeat containing 2 0.00310678641 0.007702469657 1.5305 1.3398 1.2155 2.5018 1.8000 0.4634 1.2367283104 SBF2-AS1 hypothetical protein LOC283104 0.00820344675 0.01818211778 1.5304 1.7215 0.9721 1.5567 1.5545 0.8228 1.34088636 SSNA1 Sjogren syndrome nuclear autoantigen 1 1.40724111E-07 8.9937424E-07 1.5293 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

117584 RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 0.0001631784 0.000534240413 1.5288 1.1409 1.0772 1.3056 0.9234 0.5821 0.9916152485 ZNF827 zinc finger protein 827 0.00027135561 0.000851048705 1.5288 1.0810 1.8302 1.2694 1.2104 2.0337 1.64958225 GTPBP6 GTP binding protein 6 (putative) 9.76564316E-06 4.11147078E-05 1.5287 0.0958 0.1141 0.2378 0.2030 0.1241 0.102110193 RNF41 ring finger protein 41 1.53615335E-07 9.73589802E-07 1.5282 2.4875 3.1515 2.6014 2.1144 4.9241 3.088479134 TMEM185B transmembrane protein 185B 1.28691028E-07 8.28848244E-07 1.5280 0.8869 0.9348 2.2224 0.6930 0.9331 2.27295954 RCN1 reticulocalbin 1, EF-hand calcium binding domain 1.58042952E-05 6.36751515E-05 1.5265 0.6199 0.5879 0.7403 0.7495 0.7582 0.902951545 ZNF581 zinc finger protein 581 3.33082142E-07 1.94505494E-06 1.5255 2.4425 2.5623 2.3457 2.0601 4.3670 2.269626090 ABHD12 abhydrolase domain containing 12 2.08935991E-05 8.2030048E-05 1.5252 2.3858 2.5526 0.9486 1.4687 2.7398 1.428210536 LEPREL2 leprecan-like 2 0.00687441191 0.015549548706 1.5245 1.3311 1.7653 2.1895 0.9001 1.2607 1.88058764 TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.7303199E-05 0.000104609782 1.5244 1.8069 2.9728 3.5118 1.1076 2.4584 2.910879954 NOL10 nucleolar protein 10 4.55813355E-07 2.56739261E-06 1.5233 2.7932 1.5318 2.5748 2.9656 2.2293 2.788110311 DSCR3 Down syndrome critical region gene 3 1.22756919E-07 7.94679154E-07 1.5220 1.6223 2.5657 1.6421 1.7972 3.3753 2.77115141 PDE4A phosphodiesterase 4A, cAMP-specific 0.00026618297 0.00083698075 1.5220 0.5766 0.9239 1.1742 0.4533 0.8156 1.0175

8888 MCM3AP 2.98818854E-07 1.76528228E-06 1.5206 0.4454 0.4790 0.7629 0.2529 0.3199 0.45235557 PRIM1 primase, DNA, polypeptide 1 (49kDa) 4.59434204E-05 0.000168739332 1.5204 2.1756 2.2473 1.4760 2.3460 3.2072 2.445454914 FOCAD focadhesin 8.84733519E-06 3.76037471E-05 1.5198 0.4807 0.6700 0.4626 0.8602 0.4438 0.810955362 TMEM63B transmembrane protein 63B 0.00059446929 0.001726890749 1.5198 0.1708 1.0912 0.3065 0.3105 0.2430 0.23214598 MVK mevalonate kinase 0.00078238945 0.002219847822 1.5186 0.7937 0.7714 0.9424 0.4535 0.6112 0.572455705 IPO9 importin 9 2.46950236E-08 1.9039845E-07 1.5171 1.7671 0.9918 1.2856 2.7117 1.5177 1.556511022 TDRKH tudor and KH domain containing 0.00185202566 0.004833625617 1.5164 1.5487 1.6952 1.9320 1.5418 2.1185 2.6746100499489 LOC100499489 uncharacterized LOC100499489 0.00908376575 0.019875292516 1.5155 1.9467 3.3344 2.3803 1.9296 2.6770 2.713151015 ISOC1 isochorismatase domain containing 1 1.93910966E-06 9.50158533E-06 1.5150 2.1526 1.5059 2.1314 1.9499 1.5776 2.64632790 GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00326862751 0.00804910538 1.5150 2.5001 1.9559 1.4219 2.0650 2.2892 2.0492

10505 SEMA4F 0.00353114868 0.008628129008 1.5149 1.7340 1.4685 1.8737 1.5010 1.1045 2.098858491 ZNF71 zinc finger protein 71 0.00018621766 0.000602544551 1.5147 1.3389 1.5258 1.9552 1.3602 1.6116 1.954626589 MRPL46 mitochondrial ribosomal protein L46 8.64231973E-06 3.68008544E-05 1.5141 0.3946 0.8328 0.7695 0.4421 0.7273 0.60602058 EPRS glutamyl-prolyl-tRNA synthetase 6.08276583E-06 2.67302302E-05 1.5138 2.0487 1.8071 1.4211 2.7134 3.9025 2.227710653 SPINT2 serine peptidase inhibitor, Kunitz type, 2 3.50335881E-06 1.62264568E-05 1.5136 1.5491 2.6786 2.2396 1.1006 1.8209 2.0221

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1

TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDaplatelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

minichromosome maintenance complex component 3 associated protein

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F

3652 IPP intracisternal A particle-promoted polypeptide 0.00829751902 0.018346111754 1.5136 2.9518 1.7729 1.6816 2.5606 2.3848 2.13661207 CLNS1A chloride channel, nucleotide-sensitive, 1A 2.6244026E-06 1.24683007E-05 1.5135 2.3473 2.9200 1.6194 2.2132 4.0626 2.2924

6924 TCEB3 1.71640515E-08 1.37916248E-07 1.5134 2.7169 2.6149 1.4885 1.9951 2.8488 1.69624676 NAP1L4 nucleosome assembly protein 1-like 4 1.27549199E-06 6.49367222E-06 1.5132 0.8969 1.3778 1.2957 0.9436 2.1459 1.959194097 SFXN5 sideroflexin 5 0.00828033195 0.01831475916 1.5131 0.3653 0.3670 0.4932 0.4335 0.7280 0.8445

6576 SLC25A1 5.78691576E-06 2.56068922E-05 1.5131 1.2126 2.7155 1.8274 0.9052 2.4699 2.5109116028 RMI2 RecQ mediated genome instability 2 0.00240222288 0.006114992545 1.5129 0.8717 0.6340 1.1967 0.7586 0.6017 1.0558643988 C1orf233 hypothetical LOC643988 0.00180530036 0.00472179333 1.5125 0.7532 1.2694 1.0476 0.4363 0.4181 0.777763891 RNF123 ring finger protein 123 6.25388627E-07 3.41446441E-06 1.5115 1.2543 1.9067 1.2519 0.8045 2.6263 1.007279411 GLB1L galactosidase, beta 1-like 0.01331722559 0.02773966553 1.5112 0.2890 0.3858 0.5483 0.3395 0.5752 0.42329639 ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.00372985774 0.009065171669 1.5106 0.6055 0.6620 0.3180 0.3625 0.8687 0.37778605 PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 0.01121846882 0.023876978716 1.5104 0.6672 0.6204 0.8028 0.4028 0.6059 0.653210425 ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 1.64332315E-07 1.03576407E-06 1.5101 1.3516 1.2354 1.8350 1.1315 0.9827 1.25539501 RPH3AL rabphilin 3A-like (without C2 domains) 0.01570160729 0.0319808013 1.5101 0.1158 0.1260 0.0761 0.1715 0.0411 0.195951093 RRNAD1 ribosomal RNA adenine dimethylase domain containing 1 0.0001498466 0.000494938021 1.5101 0.3761 9.2200 2.9622 0.2197 12.1739 1.22859673 SLC25A44 solute carrier family 25, member 44 1.0060412E-05 4.22486437E-05 1.5099 2.2811 1.9584 2.5684 2.1227 2.2853 3.2530391 RHOG ras homolog family member G 1.11396985E-06 5.74335697E-06 1.5089 2.2871 2.4145 1.9490 2.1257 2.7537 3.101964149 C17orf75 chromosome 17 open reading frame 75 7.19286924E-05 0.000254705633 1.5089 1.6387 3.1314 1.8786 1.3570 3.3567 1.98415292 PIM1 pim-1 oncogene 0.00014533393 0.000481949479 1.5085 2.3560 2.6150 2.2760 2.7438 3.1774 3.595890441 ZNF622 zinc finger protein 622 4.78948539E-07 2.6819944E-06 1.5081 2.4059 4.1927 1.9836 2.5267 6.6460 3.135192154 MTSS1L metastasis suppressor 1-like 0.01645814726 0.033306468597 1.5081 0.2100 0.4675 0.5197 0.1066 0.3896 0.362722876 INPP5F inositol polyphosphate-5-phosphatase F 2.23648955E-05 8.72627311E-05 1.5079 1.3858 1.5833 1.0872 0.9192 1.3157 1.01917390 UROS uroporphyrinogen III synthase 1.6354238E-06 8.15346893E-06 1.5079 0.5403 0.9293 1.4705 0.4704 0.3153 0.898296610 LOC96610 hypothetical gene LOC96610 0.00388344347 0.009387257457 1.5071 2.7912 2.8177 1.3417 2.5395 3.9748 1.950855781 RIOK2 RIO kinase 2 8.11113251E-06 3.47413533E-05 1.5069 2.5333 3.1702 1.5896 3.1011 5.1057 2.079727343 POLL polymerase (DNA directed), lambda 1.10027511E-06 5.68237052E-06 1.5069 0.7699 0.4959 1.4975 0.4656 0.2603 0.3233149603 RNF187 ring finger protein 187 2.49256126E-06 1.19069488E-05 1.5068 1.9727 1.3585 1.7485 1.6452 1.9810 3.08516277 S100A6 S100 calcium binding protein A6 0.00210217259 0.005429102136 1.5065 1.6366 2.7760 2.0542 1.3401 4.1460 2.355951106 TFB1M transcription factor B1, mitochondrial 0.00066040034 0.001899092714 1.5065 1.9924 3.4628 1.9999 2.0801 3.7018 2.797356941 C3orf37 chromosome 3 open reading frame 37 2.38009533E-08 1.84305226E-07 1.5057 1.9050 2.6930 1.4186 1.6033 2.4410 1.507029924 EPN1 epsin 1 1.7515976E-07 1.09456879E-06 1.5057 2.3071 2.0240 1.9358 1.5110 1.7940 1.9310151963 MB21D2 Mab-21 domain containing 2 0.00466253215 0.011064128228 1.5056 1.2831 2.3132 1.4885 1.8498 2.4244 1.78287549 ZNF2 zinc finger protein 2 0.00845630255 0.018656551578 1.5053 2.0591 2.6616 1.6397 2.0156 4.1238 2.314510682 EBP emopamil binding protein (sterol isomerase) 8.02942641E-05 0.000282087444 1.5045 2.1737 2.2874 2.7959 1.4931 2.7608 2.00129777 TM9SF4 transmembrane 9 superfamily protein member 4 4.69219918E-07 2.63640416E-06 1.5044 1.9355 1.2472 1.2993 2.9292 2.0789 1.865355181 SMG8 SMG8 nonsense mediated mRNA decay factor 9.45320414E-07 4.94587639E-06 1.5039 1.4162 1.6137 1.8722 1.8559 2.6797 2.4951550 AUP1 ancient ubiquitous protein 1 5.09312882E-07 2.83465275E-06 1.5038 0.6607 1.5950 0.6915 0.6477 0.9797 0.497710169 SERF2 small EDRK-rich factor 2 3.5465064E-06 1.63930597E-05 1.5033 0.1991 0.2766 0.1829 0.4310 0.2469 0.56997979 SHFM1 split hand/foot malformation (ectrodactyly) type 1 2.92103472E-05 0.000111240405 1.5032 2.0331 1.7408 1.3360 2.5829 2.9724 1.667051029 DESI2 desumoylating isopeptidase 2 2.36984162E-05 9.17798771E-05 1.5013 2.9056 2.2782 1.8174 2.1161 3.2971 2.184857122 NUP107 nucleoporin 107kDa 9.77505284E-05 0.000336491646 1.5011 0.9593 5.8156 2.3516 0.8430 4.9878 1.7697309 ANXA6 annexin A6 5.09289904E-07 2.83465275E-06 1.5009 1.7430 1.7197 2.2617 1.1324 1.4239 1.8643

79796 ALG9 9.51143947E-05 0.000328221005 1.5008 1.2093 0.9848 0.7614 1.1477 1.2648 1.08629592 IER2 immediate early response 2 0.00010873929 0.000370825742 1.5005 5.1302 1.0884 2.0039 3.3247 0.6582 1.96859928 KIF14 kinesin family member 14 0.01685952254 0.034009405585 1.5003 1.4737 1.2798 1.2177 1.0723 1.1240 1.12698665 EIF3F eukaryotic translation initiation factor 3, subunit F 1.47388558E-06 7.40672091E-06 1.5001 2.1750 1.4271 1.5519 1.9319 1.8294 2.189823463 ICMT isoprenylcysteine carboxyl methyltransferase 9.11086457E-05 0.000315589986 1.4993 1.3941 2.2308 1.4976 0.7294 1.7948 1.704181575 APOLD1 apolipoprotein L domain containing 1 0.00342939623 0.008405355856 1.4990 0.3927 0.5177 0.6397 0.4077 0.3667 0.4568

84920 ALG10 0.00508794246 0.011960232175 1.4990 2.2820 1.9198 1.7575 1.9739 2.1440 2.25782187 FANCB Fanconi anemia, complementation group B 0.01028057256 0.022156949974 1.4989 0.4281 50.5575 0.9030 0.4173 34.7169 0.34675547 PRCP prolylcarboxypeptidase (angiotensinase C) 2.84005853E-06 1.33876698E-05 1.4982 2.3065 2.3493 2.1984 1.2710 2.1601 2.233955646 LYAR Ly1 antibody reactive 0.00043283698 0.001294614074 1.4981 1.0412 1.9893 1.1523 0.7163 1.2368 0.70403007 HIST1H1D histone cluster 1, H1d 0.00034268354 0.001051295093 1.4978 2.3549 2.1574 2.0707 2.1263 2.1274 2.041779807 GSTCD glutathione S-transferase, C-terminal domain containing 0.01674348142 0.033801446518 1.4975 0.3624 0.4951 0.3653 0.3861 0.3643 0.40345306 PITPNA phosphatidylinositol transfer protein, alpha 4.66747299E-08 3.35367937E-07 1.4964 1.2196 1.7671 0.7537 0.9870 1.2946 0.968723197 FAF2 Fas associated factor family member 2 3.94200247E-07 2.25723187E-06 1.4949 1.8236 2.8626 2.1049 1.9603 3.4530 3.04024701 NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 3.93711613E-07 2.25584779E-06 1.4949 4.1949 18.7300 0.7159 2.1827 8.1765 1.4628

10478 SLC25A17 1.78644382E-06 8.83114757E-06 1.4946 2.1284 1.5322 2.4767 1.7309 1.8937 2.522310096 ACTR3 ARP3 actin-related protein 3 homolog (yeast) 1.38604931E-06 7.0096576E-06 1.4940 2.0732 1.5744 1.8672 2.2102 3.3425 3.1920

6715 SRD5A1 0.01468619958 0.030187311443 1.4933 1.7782 2.2694 0.3428 0.4785 0.4577 2.054184902 CEP89 coiled-coil domain containing 123 0.00280186657 0.007014071234 1.4933 0.2670 1.3285 0.4834 0.3083 0.7976 0.418010073 SNUPN snurportin 1 0.0002187481 0.000697794226 1.4931 1.1347 1.3273 1.4410 0.9539 1.5118 1.23947589 ZSCAN21 zinc finger and SCAN domain containing 21 0.01352582432 0.028122879146 1.4927 1.8987 1.8807 1.5402 1.7153 2.1673 1.93676835 SURF2 surfeit 2 2.96551796E-06 1.39259687E-05 1.4922 0.3602 25.9086 1.3143 0.3785 2.8836 0.422384321 THOC3 THO complex 3 2.86935166E-06 1.35160592E-05 1.4916 1.2808 1.6565 1.2084 1.3344 2.8870 1.751780017 C14orf159 chromosome 14 open reading frame 159 4.03846433E-06 1.84062909E-05 1.4915 2.5407 2.5988 2.1682 2.1120 2.1784 2.09401326 MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.00422348644 0.010135479938 1.4913 2.1536 2.6268 1.3700 1.6536 2.5960 1.38209690 UBE3C ubiquitin protein ligase E3C 6.1578691E-07 3.36876E-06 1.4911 1.0666 0.7531 0.8780 0.9545 1.3432 0.979355374 TMCO6 transmembrane and coiled-coil domains 6 0.00511659782 0.012016770619 1.4911 1.4014 1.2994 1.2187 1.3371 1.5012 1.1568157769 FAM91A1 family with sequence similarity 91, member A1 1.10378313E-06 5.69726706E-06 1.4904 1.8792 2.1873 2.2385 1.6330 3.6170 2.6002

6878 TAF6 6.25588623E-08 4.36288371E-07 1.4901 1.1491 0.3575 1.0776 0.6940 0.3472 0.8087285282 RABL3 RAB, member of RAS oncogene family-like 3 0.00018403027 0.00059614845 1.4896 2.1942 4.3523 7.8309 1.5522 6.5474 4.1531445328 ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35 0.00521226342 0.01220693119 1.4893 2.7960 1.9782 2.2948 2.0263 1.6452 2.130890809 TMEM55B transmembrane protein 55B 6.32854648E-07 3.4466528E-06 1.4890 1.4448 2.8475 2.1654 1.2231 3.5229 2.268653981 CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 2.66636398E-08 2.03678105E-07 1.4889 3.6947 1.4244 3.2835 3.6103 0.6664 2.951960436 TGIF2 TGFB-induced factor homeobox 2 5.33598033E-08 3.7775681E-07 1.4883 1.9991 1.8536 2.1606 1.1040 1.6983 1.931110539 GLRX3 glutaredoxin 3 2.93253774E-07 1.73577355E-06 1.4880 0.9195 1.0368 1.3558 0.8148 1.0800 1.26209364 RAB28 RAB28, member RAS oncogene family 0.00143625929 0.003853646083 1.4878 2.0043 2.1924 1.9246 1.9866 2.9054 2.26672963 GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 2.53427547E-06 1.20841026E-05 1.4876 2.9717 2.2799 2.2286 2.8294 3.5852 2.78689148 NEURL neuralized E3 ubiquitin protein ligase 1 0.01017285574 0.02194990072 1.4864 1.5198 1.2845 1.3135 0.8540 0.5851 0.971023196 FAM120A family with sequence similarity 120A 1.6852107E-06 8.36971186E-06 1.4863 0.2663 0.2277 0.3053 0.3177 0.1807 0.33512868 GRK4 G protein-coupled receptor kinase 4 0.01015875565 0.021922851459 1.4860 2.7447 2.5988 3.2908 0.7169 2.0857 1.862523517 SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 4.61421518E-08 3.32456387E-07 1.4843 6.4588 3.3153 0.6368 1.2742 1.8538 0.326857862 ZNF410 zinc finger protein 410 1.53969298E-07 9.75494805E-07 1.4843 1.1633 1.1129 1.4759 0.8458 1.5761 1.44275387 PMS2P3 postmeiotic segregation increased 2 pseudogene 3 0.00961356231 0.020887147396 1.4836 2.2434 2.1709 1.5767 2.1692 3.6412 1.9079159195 USP54 ubiquitin specific peptidase 54 0.00757181449 0.016923815832 1.4831 0.3403 0.2899 0.3807 0.3883 0.1247 0.285110062 NR1H3 nuclear receptor subfamily 1, group H, member 3 0.00859976339 0.018934194079 1.4826 0.4367 0.2299 0.3815 0.3982 0.0797 0.21987873 MANF mesencephalic astrocyte-derived neurotrophic factor 0.0016595061 0.004386300515 1.4824 1.9635 2.1371 1.9891 1.6256 3.6215 3.399964743 WDR13 WD repeat domain 13 4.38158815E-07 2.48249236E-06 1.4823 0.8588 1.5637 0.9087 1.0820 2.8271 1.345088745 RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) 7.25994276E-08 4.98510613E-07 1.4807 2.4771 1.7445 1.6208 2.3324 1.3661 2.2836100271835 LIMS3-LOC4408 LIMS3-LOC440895 readthrough 0.01410586483 0.029167371057 1.4807 0.4404 0.5610 0.6136 0.5376 0.2534 0.4675

80207 OPA3 4.62543151E-06 2.08526732E-05 1.4798 1.2654 1.3197 1.1003 1.4137 2.8642 1.460884278 HIATL2 hippocampus abundant transcript-like 2 0.00878070459 0.019281460675 1.4797 2.0829 1.4257 1.4076 2.0137 2.0664 2.1363163 AP2B1 adaptor-related protein complex 2, beta 1 subunit 1.88535061E-06 9.26799203E-06 1.4773 1.3902 1.3576 1.1035 1.5038 1.7166 1.261779135 APOO apolipoprotein O 0.01004836487 0.021723396011 1.4773 1.0193 0.6370 3.1301 2.0893 0.3691 2.178955276 PGM2 phosphoglucomutase 2 1.83259826E-06 9.02810336E-06 1.4766 2.5978 2.6098 2.6890 2.7228 3.9599 3.508326355 FAM162A family with sequence similarity 162, member A 7.84864052E-05 0.000276267308 1.4763 2.2180 4.4666 1.8844 1.5899 4.1765 2.161611171 STRAP serine/threonine kinase receptor associated protein 3.89559619E-06 1.78441548E-05 1.4758 1.7405 2.7773 1.8656 2.4526 3.8464 2.91315790 PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 4.35158406E-05 0.000160695521 1.4751 1.3852 1.5831 2.9026 1.5215 2.8291 3.924351497 NELFCD negative elongation factor complex member C/D 2.62925315E-06 1.24880981E-05 1.4748 1.4045 2.0614 2.1085 1.1023 3.8131 2.75101912 PHC2 eukaryotic translation elongation factor 1 alpha 2 2.17724746E-06 1.05300862E-05 1.4743 1.1649 1.3027 1.0900 0.9106 0.9040 1.29808496 PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.00440108039 0.010510592199 1.4735 1.0149 1.1784 1.1975 1.2167 1.0355 1.457125828 TXN2 thioredoxin 2 3.44855705E-07 2.0057009E-06 1.4733 2.5814 2.0374 2.4354 2.0346 2.4443 2.86246723 SRM spermidine synthase 0.00163786611 0.00433725937 1.4733 1.6770 2.6670 2.0654 0.9359 3.6758 2.94679941 EXOG endo/exonuclease (5'-3'), endonuclease G-like 0.00713354248 0.016056182328 1.4732 1.2063 1.8682 1.7607 1.3056 1.8580 2.1682

55319 TMA16 Q96EY4,translation machinery associated 16 homolog (S. cerevisiae) 0.00014998697 0.000495222593 1.4710 2.4216 1.6891 1.6676 2.3619 2.5896 2.57569265 CYTH3 cytohesin 3 0.01355373627 0.028174501615 1.4710 0.9641 0.8152 0.8985 0.8577 0.9926 0.704191544 UBXN11 UBX domain protein 11 0.00039904759 0.00120651792 1.4693 2.8517 2.6798 2.3243 3.3661 2.5113 2.67255993 RFX5 regulatory factor X, 5 (influences HLA class II expression) 9.96662801E-07 5.18980413E-06 1.4692 1.9795 1.3254 2.4919 1.6918 1.2655 1.851691949 COG7 component of oligomeric golgi complex 7 3.05170481E-06 1.42902999E-05 1.4691 1.8652 1.6525 1.9181 1.9923 2.3844 2.766451 ACOX1 acyl-CoA oxidase 1, palmitoyl 1.33835227E-07 8.59254134E-07 1.4689 1.9045 1.4163 2.5939 2.0076 1.5770 3.79336117 RPA1 replication protein A1, 70kDa 1.57299457E-06 7.86153086E-06 1.4689 0.4670 2.5442 0.7284 1.4812 0.7718 0.25681457 CSNK2A1 casein kinase 2, alpha 1 polypeptide 5.30888128E-07 2.94040251E-06 1.4684 1.7881 1.9764 1.7688 1.8122 2.4578 1.69328357 HIST1H3H histone cluster 1, H3h 0.00269282422 0.006775445353 1.4683 1.0889 2.3670 2.9051 1.7657 0.9276 1.434010741 RBBP9 retinoblastoma binding protein 9 8.34576634E-05 0.000292133798 1.4682 1.6988 1.8702 1.7668 1.4805 2.2391 1.70089446 GSTO1 glutathione S-transferase omega 1 9.97604623E-06 4.19232559E-05 1.4679 1.4649 2.1682 1.8094 1.3135 2.1390 1.52758359 HIST1H4A histone cluster 1, H4a 0.00546082852 0.012697920434 1.4678 1.7015 1.8435 2.0336 1.5220 1.7425 2.84151762 DMWD DNA replication helicase/nuclease 2 2.57942645E-05 9.92446411E-05 1.4660 1.3892 0.4985 1.1173 0.8040 0.6639 0.92825681 PSKH1 protein serine kinase H1 2.26373249E-06 1.09108204E-05 1.4649 2.5689 2.2502 1.9593 2.1235 2.4908 1.9253

548593 SLX1A 7.99958125E-06 3.43440669E-05 1.4646 1.0772 2.1856 1.0506 0.7023 1.1850 0.83754802 NFYC nuclear transcription factor Y, gamma 4.14419171E-08 3.02648565E-07 1.4643 1.3014 1.9696 1.2189 1.0395 1.1868 1.049523309 SIN3B SIN3 transcription regulator family member B 4.48356159E-06 2.027311E-05 1.4636 0.7637 0.5276 0.6226 0.5724 0.3420 0.58922769 GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.02323520957 0.044902564703 1.4634 0.4375 0.8118 2.0293 0.3565 0.8765 1.65256829 SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.36927723E-06 1.13715349E-05 1.4628 0.8827 1.0045 0.8627 0.8999 1.4969 1.187357670 KIAA1549 KIAA1549 0.01935001243 0.038359704678 1.4627 1.1984 0.8519 1.1852 0.7076 0.6802 0.874979568 C2orf47 chromosome 2 open reading frame 47 1.64015376E-05 6.5894656E-05 1.4624 1.5651 4.9429 4.2249 1.2998 1.9673 3.890010594 PRPF8 pre-mRNA processing factor 8 1.31733515E-06 6.69550704E-06 1.4620 1.3482 1.4239 2.1198 1.7156 1.9722 2.81769861 PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 6.25449452E-07 3.41446441E-06 1.4611 1.4383 1.7185 1.1915 1.6649 2.1335 1.74872071 ERCC3 excision repair cross-complementation group 3 4.85109664E-08 3.47468592E-07 1.4598 1.1831 1.5972 1.2135 1.1163 2.1912 1.1402207 AKT1 v-akt murine thymoma viral oncogene homolog 1 2.46866736E-06 1.18175243E-05 1.4598 0.3188 1.0103 0.6534 0.2422 0.4800 0.58083006 HIST1H1C histone cluster 1, H1c 0.00029771252 0.000925923958 1.4597 2.7940 2.9916 2.1300 2.8105 2.8749 1.896928958 COA3 cytochrome c oxidase assembly factor 3 1.79163826E-07 1.11729742E-06 1.4576 21.0556 2.6061 0.9736 4.7820 1.3422 0.418010907 TXNL4A thioredoxin-like 4A 4.10159473E-07 2.33544216E-06 1.4574 2.0219 2.5683 1.8625 1.5561 3.9294 1.6162151194 METTL21A methyltransferase like 21A 9.65257382E-06 4.06761598E-05 1.4569 1.5277 1.5990 2.1335 1.5952 2.2655 2.6983

transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)

solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1

asparagine-linked glycosylation 9 homolog (S. cerevisiae, alpha- 1,2-mannosyltransferase)

asparagine-linked glycosylation 10 homolog (yeast,alpha-1,2-glucosyltransferase)

solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

55071 C9orf40 chromosome 9 open reading frame 40 0.00028379334 0.000885951133 1.4558 1.0080 3.0692 1.8764 1.1169 3.8747 2.9213256364 EML3 echinoderm microtubule associated protein like 3 6.31400652E-07 3.44033038E-06 1.4556 0.9688 0.6891 1.8673 0.3972 0.8925 1.4200372 ARCN1 archain 1 1.84778421E-06 9.09555849E-06 1.4555 3.3115 2.6595 2.7085 3.1384 3.9853 3.8904148046 CIRBP-AS1 chromosome 19 open reading frame 23 0.02372139888 0.045755030128 1.4555 2.1924 2.2497 1.4966 1.4367 1.3861 0.93206388 SDF2 stromal cell-derived factor 2 9.28846062E-07 4.86858154E-06 1.4550 4.0735 4.7552 2.3727 0.7387 3.3585 1.076154776 PPP1R12C protein phosphatase 1, regulatory subunit 12C 3.51679137E-07 2.04190696E-06 1.4542 1.2113 1.4210 1.2154 1.1426 2.0272 1.2673100507321 ERVK13-1 endogenous retrovirus group K13, member 1 0.01173340476 0.024851370319 1.4540 2.0854 2.1824 1.7066 1.7748 2.6955 2.532580152 CENPT centromere protein T 5.17672181E-05 0.000188236937 1.4537 1.2880 4.2839 1.9417 0.8778 3.2794 1.08157280 TUBB2A tubulin, beta 2A class IIa 0.00109293467 0.003011173435 1.4503 1.1377 0.8092 0.9413 0.9763 0.5739 0.81444835 NQO2 NAD(P)H dehydrogenase, quinone 2 2.69354644E-05 0.000103244138 1.4480 1.1381 1.6601 1.2711 0.8979 1.7077 1.7280652276 LOC652276 potassium channel tetramerization domain containing 5 pseudogene 0.00125211082 0.003407083972 1.4468 1.8803 1.9243 1.9275 1.5113 2.6654 2.681179147 FKRP fukutin related protein 0.00165710806 0.004381229713 1.4457 1.6135 3.7266 3.1505 0.6662 2.1796 2.040881 ACTN4 actinin, alpha 4 8.87727101E-06 3.77046713E-05 1.4456 1.8489 2.4489 1.4725 1.4931 2.5022 1.483984191 FAM96A family with sequence similarity 96, member A 1.16053384E-05 4.80409476E-05 1.4437 2.0165 2.8385 2.5002 2.1020 3.4293 3.1513348793 WDR53 WD repeat domain 53 0.00920916999 0.020118358936 1.4432 0.7964 0.6168 1.5660 0.9645 1.5389 0.835629965 CDIP1 cell death-inducing p53 target 1 1.16369041E-07 7.58037478E-07 1.4424 0.8666 1.4086 1.2744 0.6933 1.0583 1.366111057 ABHD2 abhydrolase domain containing 2 3.08180473E-07 1.81355027E-06 1.4412 1.3305 1.7851 2.0168 1.3179 2.2808 2.5736

8514 KCNAB2 2.10595862E-06 1.0223187E-05 1.4410 1.8795 6.2526 2.8255 1.4412 3.3987 1.869185377 MICALL1 MICAL-like 1 1.43861109E-05 5.8388054E-05 1.4410 0.7534 2.7670 2.0617 0.5163 1.7948 1.763979637 ARMC7 armadillo repeat containing 7 3.80871172E-05 0.000142316525 1.4406 1.9132 2.6048 1.8921 1.2231 2.1317 1.738322909 FAN1 FANCD2/FANCI-associated nuclease 1 0.00603989511 0.013878390771 1.4405 1.7375 1.3737 1.6266 1.4531 1.9203 1.896010866 HCP5 HLA complex P5 (non-protein coding) 4.29713774E-06 1.94832012E-05 1.4376 0.8629 0.7774 0.7425 0.9498 0.8917 0.8886199990 C1orf86 chromosome 1 open reading frame 86 7.39927062E-07 3.96828508E-06 1.4368 0.5673 1.0157 0.9786 0.6436 0.6621 1.032090529 STPG1 sperm-tail PG-rich repeat containing 1 0.01254896843 0.026340580258 1.4368 1.0656 1.5840 0.9979 0.7395 1.1041 0.815584295 PHF6 PHD finger protein 6 1.38292754E-05 5.63659424E-05 1.4342 2.3242 2.4709 1.5291 2.8032 4.3880 1.92901201 CLN3 ceroid-lipofuscinosis, neuronal 3 1.52728635E-07 9.68978341E-07 1.4336 1.6482 1.3253 1.2948 1.6218 1.9479 1.184751337 THEM6 thioesterase superfamily member 6 6.74394018E-06 2.93813245E-05 1.4335 4.8811 8.4820 3.6278 3.1957 9.8281 2.28074489 MT1A metallothionein 1A 0.01973510857 0.038996420865 1.4316 0.4253 0.4239 0.6898 0.4086 0.3571 0.657384899 TMTC4 transmembrane and tetratricopeptide repeat containing 4 0.0007378191 0.002104172085 1.4314 1.0335 1.0581 0.6906 0.8581 2.0088 0.9635606495 CYB5RL hypothetical protein LOC606495 0.01335723878 0.027816670504 1.4300 0.8442 0.3336 0.5723 3.9639 0.0516 0.30644752 NEK3 NIMA-related kinase 3 0.01327694213 0.027658908524 1.4296 0.9205 0.7563 0.9475 0.6560 0.5494 0.9072

23062 GGA2 5.06840937E-07 2.82261433E-06 1.4284 1.7030 3.4690 1.4497 1.5937 4.6069 1.83935571 PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 3.99239362E-07 2.28036937E-06 1.4283 2.5975 2.3006 1.9988 2.4952 3.4525 2.38169870 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 9.0250338E-08 6.04492E-07 1.4280 2.2310 1.8987 1.4266 1.1575 1.7346 1.109157727 NCOA5 nuclear receptor coactivator 5 8.64313391E-07 4.56569364E-06 1.4266 0.5134 0.6763 0.6295 0.4762 0.7366 0.843155341 LSG1 Q9H089,large 60S subunit nuclear export GTPase 1 2.64433544E-07 1.58106339E-06 1.4263 2.7079 1.8221 1.5052 3.2270 3.9486 2.418283707 TRPT1 tRNA phosphotransferase 1 9.92705098E-05 0.000341466633 1.4259 0.5735 0.3651 1.3107 0.1752 0.1090 0.51711390 CREM cAMP responsive element modulator 0.00105909514 0.002925882428 1.4255 0.7686 1.1773 0.8398 0.8011 1.7017 0.955811140 CDC37 cell division cycle 37 4.84756583E-06 2.18003256E-05 1.4251 1.8820 15.5977 2.0538 0.6549 5.8174 2.10707277 TUBA4A tubulin, alpha 4a 0.00020464902 0.000656601735 1.4243 1.6703 1.7347 2.1290 1.5249 2.0438 2.250510998 SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.0007368802 0.002102086177 1.4229 0.5645 1.2413 0.8932 0.4939 1.3834 0.850879571 GCC1 GRIP and coiled-coil domain containing 1 2.31443823E-07 1.40361842E-06 1.4228 2.3222 2.3442 1.8174 2.1174 2.5402 1.853079660 PPP1R3B protein phosphatase 1, regulatory subunit 3B 0.00053095702 0.001560478464 1.4224 1.8961 2.0524 2.3673 1.2638 2.1360 1.8413401397 LINC00998 long intergenic non-protein coding RNA 998 0.00195288333 0.005072222346 1.4221 2.2443 1.1571 2.2596 2.5078 1.6037 1.767410238 DCAF7 DDB1 and CUL4 associated factor 7 4.26603066E-06 1.93565712E-05 1.4221 2.2871 2.6195 2.2181 2.0806 3.1588 3.067723225 NUP210 nucleoporin 210kDa 3.53676926E-06 1.63604678E-05 1.4216 0.6003 0.6487 0.8545 0.5844 0.7601 1.060057082 CASC5 cancer susceptibility candidate 5 0.00769480965 0.01716722368 1.4215 1.8490 1.7628 1.4444 1.5698 1.8295 2.359323172 FAM175B family with sequence similarity 175, member B 4.17667997E-05 0.000154654204 1.4214 1.5760 2.4870 1.8023 1.2329 3.5962 2.219656927 GPR108 G protein-coupled receptor 108 4.93310019E-06 2.21602498E-05 1.4214 1.0743 0.7727 1.0152 0.6982 1.0510 1.263355615 PRR5 proline rich 5 (renal) 0.00013348858 0.000445987092 1.4203 0.5290 1.0213 0.7169 0.4489 0.5687 0.517527309 ZNF330 zinc finger protein 330 2.32179922E-06 1.11700673E-05 1.4196 1.5026 1.0425 1.1748 1.8694 1.4903 2.09399069 CLDN12 claudin 12 0.01983731456 0.039168728293 1.4182 0.9905 1.5911 0.9122 0.9101 1.6435 0.769226190 FBXW2 F-box and WD repeat domain containing 2 1.97663629E-07 1.22223683E-06 1.4181 1.9791 10.5835 1.3443 0.6556 10.6037 1.224323352 UBR4 ubiquitin protein ligase E3 component n-recognin 4 4.7369837E-06 2.13240124E-05 1.4180 0.5266 0.3640 0.5184 0.6358 0.5770 0.5987267 AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.00013986018 0.000465826701 1.4174 0.5589 1.0082 0.6033 0.6034 1.0261 0.770590990 KIFC2 kinesin family member C2 0.00849103348 0.018724132716 1.4168 2.5676 2.3679 2.3616 1.0623 1.3871 1.940584133 ZNRF3 zinc and ring finger 3 0.01836949372 0.036666745613 1.4155 1.1130 1.4991 1.3476 1.1056 1.5866 1.0026649 BMP1 bone morphogenetic protein 1 0.0127552999 0.026712302559 1.4151 0.7644 0.8135 1.4623 0.5596 0.8612 1.2000

4706 NDUFAB1 5.64853832E-06 2.50388385E-05 1.4150 2.0788 2.0793 1.5202 2.1257 3.9978 1.69011977 EIF4E eukaryotic translation initiation factor 4E 5.25863957E-07 2.91699642E-06 1.4140 1.9246 1.8050 1.6693 2.2692 3.2654 2.1551

9368 SLC9A3R1 5.64656164E-06 2.503615E-05 1.4140 0.3467 3.4987 1.7222 0.3787 7.1666 2.14816293 VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 1.54595974E-06 7.74123769E-06 1.4126 0.5994 0.9501 1.1783 0.4260 0.5172 1.48836809 STX3 syntaxin 3 0.0046696253 0.011075206848 1.4120 1.5091 1.2595 1.7470 0.9915 0.8848 1.873027013 CNPPD1 cyclin Pas1/PHO80 domain containing 1 1.32647251E-06 6.7382001E-06 1.4119 1.5615 3.0193 2.2627 0.8649 3.3285 3.4629253980 KCTD13 potassium channel tetramerisation domain containing 13 0.00022347997 0.000711398263 1.4112 1.5107 2.2868 1.9314 1.2089 2.6371 2.359226276 VPS33B vacuolar protein sorting 33 homolog B (yeast) 7.34944947E-05 0.000259746887 1.4111 2.6713 2.0292 2.4022 2.0839 2.7397 2.5122166647 GPR125 G protein-coupled receptor 125 0.01388708444 0.028765991037 1.4103 0.6405 0.8230 0.6307 0.6433 0.9704 0.740451333 ZNF771 zinc finger protein 771 0.01082746702 0.023158079985 1.4083 1.1004 1.6293 1.8128 1.0120 1.6692 2.18929770 RASSF2 Ras association (RalGDS/AF-6) domain family member 2 2.4865473E-06 1.18906549E-05 1.4075 1.2791 1.5508 1.4179 1.1042 1.5218 1.330354531 MIER2 mesoderm induction early response 1, family member 2 0.0001286238 0.000431865855 1.4075 2.5063 5.3594 2.2027 1.4838 5.3719 1.816280019 UBTD1 ubiquitin domain containing 1 0.01690505993 0.034093736752 1.4070 0.9345 0.9284 0.7901 0.5649 0.8705 0.520151373 MRPS17 mitochondrial ribosomal protein S17 0.0005756663 0.001677603607 1.4070 1.1977 1.9973 1.6102 1.0974 2.6121 1.998751021 MRPS16 mitochondrial ribosomal protein S16 7.95496225E-07 4.23276267E-06 1.4062 3.1456 2.4529 2.2455 2.9136 3.3690 3.0342221786 FAM200A chromosome 7 open reading frame 38 0.01413708117 0.029210985772 1.4044 1.4093 1.4352 1.3346 1.5649 1.3679 1.311084936 ZFYVE19 zinc finger, FYVE domain containing 19 2.79860413E-05 0.000107046461 1.4042 0.4867 3.7151 1.5006 1.2550 2.4711 0.7835139285 AMER1 family with sequence similarity 123B 0.00040103108 0.001211580656 1.4030 1.4121 1.8016 1.8796 1.2973 1.9857 2.760710992 SF3B2 splicing factor 3b, subunit 2, 145kDa 6.31553578E-06 2.76732541E-05 1.4029 2.0822 3.1541 1.6633 2.0613 4.8914 1.812084832 ANKRD36BP1 hypothetical protein MGC12538 0.01580316654 0.032164994025 1.4023 0.2878 0.3214 0.2276 0.5982 0.1100 0.287464897 C12orf43 chromosome 12 open readingframe 43 9.09454413E-05 0.00031514415 1.4017 2.1934 1.5387 1.2109 2.5606 2.4096 1.5344

1743 DLST 1.40631459E-06 7.09643198E-06 1.4016 2.4117 2.5956 2.2590 1.9637 3.5099 2.35071659 DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 3.29412147E-07 1.92670254E-06 1.4011 2.3108 2.7618 1.9096 2.3611 3.0249 2.311923130 ATG2A autophagy related 2A 1.76291333E-07 1.10088696E-06 1.4011 0.8734 1.5748 1.2180 0.6190 1.8956 1.38756513 SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00026955414 0.000846488744 1.4010 0.2681 1.3922 0.2901 0.3568 0.5425 0.1946

257068 PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2 0.01269060921 0.026592065531 1.4010 2.5696 1.8105 1.7849 2.1011 2.5043 2.4717

6597 SMARCA4 3.90484081E-06 1.78775373E-05 1.4008 0.6455 0.9054 0.5692 0.5393 1.0755 0.873025778 DSTYK dual serine/threonine and tyrosine protein kinase 4.34811145E-06 1.97045368E-05 1.4005 1.1101 1.7396 1.5481 0.9617 2.0522 1.550710328 EMC8 ER membrane protein complex subunit 8 2.65765204E-07 1.5869483E-06 1.4000 1.1191 0.3033 3.2433 0.3561 0.8765 0.165983983 TSSK6 testis-specific serine kinase 6 0.0166156687 0.033587952037 1.4000 0.2243 3.0756 0.9502 0.2002 1.2647 0.76543065 HDAC1 histone deacetylase 1 4.40373644E-06 1.99467209E-05 1.3999 0.9436 1.6982 1.1325 0.9854 2.1939 1.3068

2055 CLN8 0.00027627956 0.000864562448 1.3990 1.6042 1.5192 2.3577 1.5589 1.9301 3.187051429 SNX9 sorting nexin 9 0.00011885318 0.000401866279 1.3989 1.2649 1.5548 1.1951 1.1970 1.8245 1.971179877 DCAKD dephospho-CoA kinase domain containing 2.37191839E-05 9.18213829E-05 1.3987 1.4393 1.2514 2.3856 1.0673 0.9648 2.255179154 DHRS11 short-chain dehydrogenase/reductase 0.0199960047 0.039447959182 1.3981 1.0864 1.7182 1.6785 0.8313 1.4635 1.4293128 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 5.31205207E-07 2.94126713E-06 1.3970 3.6617 1.6309 0.9452 0.6008 1.0044 0.57461186 CLCN7 chloride channel, voltage-sensitive 7 6.00981769E-05 0.000215909141 1.3964 0.8823 1.4186 0.9956 0.7219 1.4657 1.3779253512 SLC25A30 solute carrier family 25, member 30 0.00574808904 0.013288092482 1.3957 1.3007 1.2825 0.7391 1.3718 1.4362 1.209855626 AMBRA1 autophagy/beclin-1 regulator 1 2.27194473E-07 1.38008557E-06 1.3956 1.0377 1.6210 0.8647 0.9472 1.5520 0.796679797 ZNF408 zinc finger protein 408 4.51710226E-05 0.000166102822 1.3948 1.6611 5.6518 1.2477 1.2198 3.9729 0.861022985 ACIN1 apoptotic chromatin condensation inducer 1 3.54599468E-06 1.63930597E-05 1.3944 2.0532 3.5388 1.0712 1.1012 3.2459 0.71182872 MKNK2 MAP kinase interacting serine/threonine kinase 2 1.28646475E-05 5.2775671E-05 1.3944 0.7393 1.2924 1.1375 0.6519 1.0716 1.0772375061 FAM89A family with sequence similarity 89, member A 0.00021975252 0.000700631327 1.3928 1.6198 2.3948 1.1775 1.0511 2.4039 1.481280223 RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00032027593 0.000989362945 1.3928 0.6800 0.4250 0.7898 0.5769 0.5362 0.84762633 GBP1 guanylate binding protein 1, interferon-inducible 0.02371717331 0.045751709319 1.3917 2.8542 1.9743 2.5453 3.0085 2.4035 2.643684080 ENKD1 chromosome 16 open reading frame 48 0.00373337774 0.009072520021 1.3913 0.3392 0.4819 0.9703 0.2032 0.4823 0.754883590 TMUB1 transmembrane and ubiquitin-like domain containing 1 4.72670281E-07 2.65497429E-06 1.3910 1.5668 1.8900 1.6645 1.2413 1.6259 1.59306611 SMS spermine synthase 2.24512592E-05 8.75062731E-05 1.3910 1.0393 0.6908 0.7034 1.1279 0.5526 0.7993755 C21orf2 chromosome 21 open reading frame 2 4.05371294E-05 0.000150639502 1.3909 0.8020 0.8834 0.7161 0.5139 0.5839 0.733879594 MUL1 mitochondrial E3 ubiquitin protein ligase 1 1.28394819E-06 6.53490289E-06 1.3909 1.7754 2.2674 1.6186 1.7940 3.8215 1.965958505 OSTC oligosaccharyltransferase complex subunit (non-catalytic) 6.17867167E-05 0.000221583295 1.3905 3.1944 2.5145 1.8027 2.8279 3.9000 2.860022916 NCBP2 nuclear cap binding protein subunit 2, 20kDa 3.15993972E-06 1.47517677E-05 1.3905 2.8221 3.4250 3.5269 1.2390 4.6953 3.606779176 FBXL15 F-box and leucine-rich repeat protein 15 1.03752591E-05 4.34211484E-05 1.3905 1.8485 0.2546 0.9736 2.2230 1.0674 5.16224833 NME4 NME/NM23 nucleoside diphosphate kinase 4 4.9388513E-05 0.000180269059 1.3904 0.4746 1.4530 0.6428 0.4963 0.7888 0.611451194 IPO11 importin 11 0.00025123643 0.000793945362 1.3898 0.7656 1.0488 0.6751 0.7835 1.1101 0.6588

4726 NDUFS6 2.36820493E-05 9.17748473E-05 1.3888 4.3844 4.2471 2.8971 4.4195 5.9631 4.2242133015 PACRGL PARK2 co-regulated-like 0.01615946274 0.032792725802 1.3884 1.0880 0.8855 0.9373 1.1911 1.0608 1.039065005 MRPL9 mitochondrial ribosomal protein L9 1.97446697E-07 1.22172233E-06 1.3883 1.4032 1.1536 1.9183 0.7465 0.8577 1.551028512 NKIRAS1 NFKB inhibitor interacting Ras-like 1 0.01430556307 0.029509059418 1.3879 0.7231 0.6569 0.8204 0.6598 0.4376 0.40845723 PSPH phosphoserine phosphatase 0.00472437755 0.011194893858 1.3877 0.2772 0.7965 0.9866 0.4011 1.0785 1.007855317 AP5S1 Q9NUS5,adaptor-related protein complex 5, sigma 1 subunit 0.00589783963 0.013589574497 1.3875 1.5706 2.0575 2.0576 1.6480 2.6723 2.783354961 SSH3 slingshot protein phosphatase 3 0.01071164696 0.022945469163 1.3872 1.4657 1.2414 1.8687 1.3473 1.7376 2.16475590 PRKCZ protein kinase C, zeta 0.00445675262 0.010622721602 1.3861 0.3379 0.5906 0.4341 0.2888 0.5272 0.405127183 VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.20710309E-06 6.17820385E-06 1.3853 2.7567 2.8996 2.0344 2.5125 3.5174 2.165581855 SFXN3 sideroflexin 3 8.88029565E-05 0.000308715301 1.3843 1.5418 3.2527 1.9867 1.2472 3.1203 1.676184326 C16orf13 hypothetical protein MGC13114 2.00105946E-06 9.76577813E-06 1.3838 1.6529 2.3848 1.8210 1.9829 3.1298 2.8377653583 PHLDB3 pleckstrin homology-like domain, family B, member 3 0.00015254603 0.000502973392 1.3838 0.7404 1.3288 0.8483 0.6980 2.3946 1.087823467 NPTXR neuronal pentraxin receptor 0.01000252587 0.021634251036 1.3835 0.6352 1.9936 1.1506 0.5877 1.2543 1.031029085 PHPT1 phosphohistidine phosphatase 1 3.79052667E-07 2.18280817E-06 1.3834 0.8717 4.5078 1.6397 0.8950 7.5552 3.42202869 GRK5 G protein-coupled receptor kinase 5 5.11835094E-07 2.84695612E-06 1.3831 2.9308 2.8572 1.9866 2.9224 4.6224 2.82308260 NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 2.56729149E-06 1.22192107E-05 1.3831 0.7453 1.9285 1.7964 0.7272 1.8006 1.83548340 HIST1H2BL histone cluster 1, H2bl 0.00148598066 0.003975379021 1.3823 2.1388 1.5339 2.5537 1.7181 0.6041 1.664623457 ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.01544635396 0.031553747053 1.3821 0.2913 0.4278 0.6467 0.3346 0.8630 0.55243064 HTT huntingtin 4.43111874E-06 2.00608032E-05 1.3820 4.9444 8.1620 0.5060 3.4719 2.0620 0.70267984 ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 0.00011612608 0.000393373312 1.3819 0.9430 1.3569 1.1981 0.8692 0.9728 0.984383986 ITFG3 integrin alpha FG-GAP repeat containing 3 0.00776921099 0.01732052504 1.3817 1.2363 0.8861 0.9620 1.1668 0.9993 1.05386666 SOX12 SRY (sex determining region Y)-box 12 6.42420012E-06 2.81156849E-05 1.3811 2.2735 2.4437 1.8091 1.4412 2.6822 2.3354

potassium voltage-gated channel, shaker-related subfamily, beta member 2

golgi-associated, gamma adaptin ear containing, ARF binding protein 2

NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1

dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)

NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)

9026 HIP1R huntingtin interacting protein 1 related 3.19316619E-05 0.000120573533 1.3801 0.8029 0.8322 0.7649 0.8180 0.7577 0.7847140701 ABHD16B chromosome 20 open reading frame 135 0.01421797213 0.029354891151 1.3800 0.0676 0.5040 0.2455 0.2099 0.2740 0.280654788 DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 2.39786807E-07 1.44934983E-06 1.3790 1.8690 1.6067 1.3988 2.4709 2.8818 2.724856654 NPDC1 neural proliferation, differentiation and control, 1 0.00521897718 0.01221639136 1.3786 0.4884 1.3013 1.0254 0.4689 1.0638 0.84648338 HIST2H2AC histone cluster 2, H2ac 0.00083844054 0.002366386402 1.3783 0.3321 0.3321 0.3321 0.3970 0.3970 0.397057600 FNIP2 folliculin interacting protein 2 0.00559369961 0.012968922633 1.3783 2.1387 3.2331 1.8875 2.0847 2.4615 2.15659889 ZBED4 zinc finger, BED-type containing 4 3.56085839E-07 2.06486844E-06 1.3781 2.2499 2.4120 2.2714 1.5807 3.4008 2.7028339123 JMJD8 jumonji domain containing 8 6.76980627E-07 3.66512297E-06 1.3766 1.8851 2.7047 1.8024 1.9124 1.9024 1.759526521 TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.00049713198 0.00146936193 1.3765 2.8687 0.6431 1.7829 2.3610 0.9206 0.876755002 TMCO3 transmembrane and coiled-coil domains 3 0.00011306443 0.000384201053 1.3753 1.8405 0.7177 1.9310 1.1602 0.2887 1.0768203286 ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 0.00033796697 0.001038242249 1.3753 0.3811 0.7014 0.7408 0.4635 0.5205 0.655510552 ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 4.18324771E-05 0.000154854745 1.3748 2.7342 2.8313 2.5956 2.3384 4.0364 3.294279066 METTL16 methyltransferase like 16 4.35862499E-07 2.47101445E-06 1.3745 2.7092 2.6058 1.9616 2.6070 3.9705 2.229555182 RNF220 ring finger protein 220 2.6293786E-05 0.000100953994 1.3744 1.2072 1.3904 1.3651 0.7610 1.0885 1.12489855 FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.01417176767 0.029269417747 1.3739 1.1795 1.9523 1.6052 0.7493 1.3949 1.45263927 LASP1 LIM and SH3 protein 1 8.60573728E-06 3.66707163E-05 1.3736 1.8416 1.8745 1.2973 2.0569 3.1803 2.90263004 GZMM granzyme M (lymphocyte met-ase 1) 0.00052015164 0.001531208423 1.3727 1.4196 1.8172 1.6716 1.0066 1.3468 1.1033100131655 LOC100131655 uncharacterized LOC100131655 0.02597045083 0.049425440897 1.3726 2.6678 2.4231 1.6286 2.9810 4.1149 2.73759810 RNF40 ring finger protein 40, E3 ubiquitin protein ligase 4.98672224E-06 2.23600954E-05 1.3706 0.7655 0.5904 0.7173 0.5199 0.5131 0.525423541 SEC14L2 SEC14-like 2 (S. cerevisiae) 0.00044592436 0.001330274283 1.3706 1.1909 0.7870 1.4935 0.9627 0.7091 0.99795195 PEX14 peroxisomal biogenesis factor 14 0.00065917888 0.001896177032 1.3699 0.9005 0.9996 1.1426 0.6467 1.2680 1.367925800 SLC39A6 solute carrier family 39 (zinc transporter), member 6 2.617254E-06 1.24375722E-05 1.3688 5.1931 4.3079 1.9300 2.3646 6.6255 1.858258516 FAM60A family with sequence similarity 60, member A 0.00269052089 0.006771514838 1.3686 2.1979 2.1367 1.8762 1.4912 1.7707 1.77046717 SRI sorcin 3.77675621E-07 2.17674026E-06 1.3686 1.3604 3.1827 1.4504 1.3532 3.6391 1.802455055 ZWILCH zwilch kinetochore protein 0.00110916583 0.003053590175 1.3685 2.0415 4.9284 3.4757 0.3490 10.8913 2.0522231 AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.45070314E-06 7.30026102E-06 1.3685 1.7487 1.9414 1.6704 1.1697 1.6740 2.192563933 MCUR1 mitochondrial calcium uniporter regulator 1 1.55422591E-05 6.26767069E-05 1.3684 1.8582 2.4637 2.1988 1.4727 2.3496 2.63612720 GLB1 galactosidase, beta 1 6.66401007E-06 2.90885791E-05 1.3681 0.4305 1.3705 0.5530 0.3372 0.8956 0.616280305 TRABD TraB domain containing 4.03736277E-06 1.84062909E-05 1.3676 1.7745 1.5745 2.0548 1.1028 3.1033 2.573257210 SLC45A4 solute carrier family 45, member 4 0.00024516529 0.00077583309 1.3673 0.1389 0.0599 0.2595 0.1854 0.0594 0.1913128308 MRPL55 mitochondrial ribosomal protein L55 3.93397847E-06 1.79974098E-05 1.3672 1.9778 3.5773 2.2676 1.8260 5.1342 2.716022980 TCF25 transcription factor 25 (basic helix-loop-helix) 3.73511909E-06 1.7199621E-05 1.3667 0.9929 1.5324 1.1031 0.7841 2.0907 1.43049290 GPR55 G protein-coupled receptor 55 0.02549309632 0.048653630248 1.3661 0.7479 1.1703 1.3235 0.5426 0.8947 0.869755686 MREG melanoregulin 0.00643088624 0.014671796745 1.3656 2.2423 2.6688 1.8212 1.4868 1.9541 1.70225300 PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 6.78381856E-07 3.67053399E-06 1.3649 0.8437 1.6927 1.3468 0.7157 1.6336 1.333484955 NUDCD1 NudC domain containing 1 2.81020429E-06 1.32579532E-05 1.3640 2.7237 0.6445 0.6271 0.6153 1.4108 0.65295443 POMC proopiomelanocortin 0.01558635602 0.031792129632 1.3638 1.0288 1.2195 1.2064 0.7368 0.7208 0.802581839 VANGL1 VANGL planar cell polarity protein 1 0.00371915133 0.009040352958 1.3636 0.6837 0.9539 1.5099 0.7689 0.6947 1.91038733 GPAA1 glycosylphosphatidylinositol anchor attachment 1 7.64722457E-06 3.29578373E-05 1.3632 1.9556 2.5301 1.2851 1.5361 2.4533 1.57441810 DR1 developmentally regulated GTP binding protein 2 2.49117995E-06 1.1906576E-05 1.3631 4.1561 1.2682 2.2757 2.2897 2.2884 2.83751497 CTNS cystinosin, lysosomal cystine transporter 0.00066890399 0.001919920479 1.3626 0.7380 60.5079 2.2495 0.3138 9.5507 0.687555052 MRPL20 mitochondrial ribosomal protein L20 2.11240415E-06 1.02491788E-05 1.3623 1.7681 4.2536 1.6219 1.3844 7.4860 2.563551562 MBIP MAP3K12 binding inhibitory protein 1 0.00476776705 0.011288925698 1.3621 2.1646 2.0679 1.4293 2.4886 3.6313 2.3105118980 SFXN2 sideroflexin 2 0.02505415605 0.047956163775 1.3612 0.8754 2.3498 3.3057 2.8128 1.3910 1.2497115509 ZNF689 zinc finger protein 689 0.0001382107 0.000460668727 1.3611 1.8006 2.0377 1.8227 1.4448 2.7860 1.96099783 RIMS3 regulating synaptic membrane exocytosis 3 0.00715228364 0.016084495593 1.3592 1.3620 2.9795 1.7592 0.8652 3.1040 1.63129442 MED27 mediator complex subunit 27 2.5934389E-06 1.23308133E-05 1.3588 2.4087 2.3794 1.4582 1.7448 2.9243 1.4909125919 ZNF543 zinc finger protein 543 0.01466436118 0.030157254631 1.3583 1.8877 0.9871 2.2864 1.8770 1.1900 2.390654927 CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 1.24937565E-05 5.14157473E-05 1.3583 1.4532 1.1859 1.3559 1.5920 1.0396 1.890510616 RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 1.43192981E-05 5.81427145E-05 1.3560 1.5764 1.2088 1.6259 1.4489 1.8312 2.478711196 SEC23IP SEC23 interacting protein 3.44894496E-07 2.0057009E-06 1.3559 1.0399 1.3514 1.3221 1.2044 1.2955 1.4908340152 ZC3H12D zinc finger CCCH-type containing 12D 0.00609422345 0.013980910548 1.3556 1.2323 1.2354 1.5406 1.0149 1.1649 1.2850100288123 LOC100288123 uncharacterized LOC100288123 0.01953759504 0.038664674175 1.3553 0.3420 0.3537 0.1430 0.9602 0.3924 0.41643178 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.00235270197 0.006001475687 1.3550 1.6868 2.7261 2.2732 1.5286 4.7347 2.3114283234 CCDC88B coiled-coil domain containing 88B 2.02535494E-05 7.96883839E-05 1.3544 0.4536 0.8059 0.8277 0.4672 0.7701 0.71144061 LY6E lymphocyte antigen 6 complex, locus E 0.00072825924 0.002078855304 1.3530 0.6081 4.1419 1.2846 0.8445 4.5724 1.4169644096 SDHAF1 hypothetical protein LOC644096 1.39028334E-05 5.66026231E-05 1.3523 1.3128 1.9101 1.8563 0.9150 2.1888 2.410623529 CLCF1 cardiotrophin-like cytokine factor 1 0.02538595509 0.048480754423 1.3515 1.1993 1.6942 1.3752 0.7476 1.0308 1.05497862 BRPF1 bromodomain and PHD finger containing, 1 3.83818039E-07 2.20746718E-06 1.3507 1.7583 2.9161 2.3037 1.9707 2.9488 3.27207621 ZNF70 zinc finger protein 70 0.02505728273 0.047957124748 1.3503 1.4429 1.9094 1.6259 1.0813 1.5805 2.13959486 CHST10 carbohydrate sulfotransferase 10 0.01704739169 0.034346668982 1.3495 2.2397 2.4081 1.7243 1.3565 1.5833 1.6388202915 TMEM184A hypothetical protein MGC9712 0.02173119304 0.042399611241 1.3484 0.1250 0.0886 0.2026 0.1651 0.0564 0.183864792 RABL5 RAB, member RAS oncogene family-like 5 0.01881826626 0.03746022019 1.3484 1.9497 1.3770 1.8408 1.4853 1.2357 1.726381857 MED25 mediator complex subunit 25 2.01508918E-05 7.93186331E-05 1.3483 0.7889 0.9913 1.1318 0.8615 1.4061 1.3130387978 C14orf23 hypothetical gene supported by BX248251 0.01799360374 0.036010857347 1.3482 0.0595 0.0362 0.1773 0.1956 0.0395 0.3274113251 LARP4 La ribonucleoprotein domain family, member 4 1.45708368E-05 5.90852931E-05 1.3481 0.6753 0.8743 0.5482 0.7550 1.4316 0.907123107 MRPS27 mitochondrial ribosomal protein S27 2.32968985E-06 1.12021297E-05 1.3473 1.4065 1.1011 0.3426 0.6471 0.2099 0.2597100133445 LOC100133445 uncharacterized LOC100133445 0.01666356204 0.033671234785 1.3468 1.7430 3.0283 1.4434 1.2341 1.5346 0.832055250 ELP2 elongator acetyltransferase complex subunit 2 3.73280229E-06 1.71932855E-05 1.3461 2.7231 2.4725 3.6567 2.3369 3.7809 3.0271129303 TMEM150A transmembrane protein 150A 0.00685074848 0.015509463045 1.3459 0.2988 0.8120 0.1550 0.5253 1.8089 0.171451182 HSPA14 heat shock 70kDa protein 14 7.33228104E-07 3.93929547E-06 1.3450 0.3321 0.3321 0.3321 0.3970 0.3970 0.397054974 THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 0.00036854116 0.001121022821 1.3444 1.6737 1.8799 1.4556 1.4782 1.3578 1.57153838 KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.00068449809 0.001960675517 1.3441 1.4289 2.0024 1.4065 1.2187 3.0015 2.269027243 CHMP2A charged multivesicular body protein 2A 1.29455388E-05 5.30717714E-05 1.3427 1.3819 3.2775 2.0411 1.0881 2.6096 1.838725861 DFNB31 deafness, autosomal recessive 31 0.01019524109 0.021988603075 1.3424 0.7589 1.4065 1.1587 0.6823 1.3447 1.068481628 TSC22D4 TSC22 domain family, member 4 9.44465418E-06 3.98735493E-05 1.3408 1.3798 1.2285 1.6344 1.4587 1.9387 2.4862662 BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 0.00319287812 0.007887017571 1.3404 0.8912 0.8522 0.8738 1.1778 0.8820 1.002128960 DCPS decapping enzyme, scavenger 9.08762364E-06 3.85264639E-05 1.3401 2.3865 3.1820 2.4328 2.3231 3.2493 3.0864401884 MGC57346 uncharacterized LOC401884 0.00596139049 0.013720434196 1.3395 0.3321 0.3321 0.3321 0.3970 0.3970 0.39704683 NBN nibrin 0.000109131 0.000371953306 1.3385 2.5625 1.8623 0.8687 2.6212 2.0480 1.83738904 CPNE1 copine I 2.12884893E-05 8.34369962E-05 1.3383 0.9445 0.6189 0.5049 0.6093 0.5040 0.40048943 AP3D1 adaptor-related protein complex 3, delta 1 subunit 1.10499337E-05 4.59918881E-05 1.3383 0.4979 1.1662 0.7785 0.3144 1.1211 0.8165151987 PPP4R2 protein phosphatase 4, regulatory subunit 2 1.85433821E-05 7.36255275E-05 1.3381 2.0888 2.1727 1.5158 1.9838 2.5499 2.24654957 ODF2 outer dense fiber of sperm tails 2 4.90317595E-07 2.73746086E-06 1.3376 0.7797 0.9662 0.6290 0.5710 0.8075 0.6612728411 GUSBP1 glucuronidase, beta pseudogene 1 6.42172615E-05 0.000229444232 1.3365 1.3890 3.0518 0.8535 1.5926 3.1777 1.3125284361 EMC10 hematopoietic signal peptide-containing 1.16275701E-05 4.81111776E-05 1.3365 0.0719 0.0040 0.5470 0.1212 0.0044 0.25332319 FLOT2 flotillin 2 1.58816198E-05 6.39323545E-05 1.3363 1.7647 2.6427 1.8447 1.8744 3.8175 2.648525930 PTPN23 protein tyrosine phosphatase, non-receptor type 23 8.33155729E-06 3.56020147E-05 1.3363 2.0952 2.0754 2.3378 2.3432 3.7228 3.01357008 TEF thyrotrophic embryonic factor 0.01143495851 0.024281180933 1.3358 0.7956 2.3998 1.0391 0.5462 2.5310 1.2192959 CD40LG CD40 ligand 0.00215758619 0.005552593644 1.3350 2.9006 2.5284 2.1778 3.3594 3.0461 2.375079143 MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0005310341 0.001560478464 1.3350 0.8929 1.2297 1.2157 0.3837 1.3573 0.890523609 MKRN2 makorin ring finger protein 2 9.51223652E-07 4.97303535E-06 1.3341 3.4772 2.3396 1.5645 3.3490 3.0518 2.058451018 RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) 0.00015778607 0.000518817177 1.3340 1.8059 1.0749 1.7662 1.8145 1.4965 2.26806732 SRPK1 SRSF protein kinase 1 1.34423071E-05 5.49603571E-05 1.3340 1.5590 2.3804 1.6064 1.2968 3.4547 2.265810695 CNPY3 canopy FGF signaling regulator 3 4.39946677E-05 0.000162299731 1.3336 1.8537 2.6656 2.0942 1.9512 5.2055 2.651564425 POLR1E polymerase (RNA) I polypeptide E, 53kDa 3.92824713E-06 1.79756903E-05 1.3331 2.1144 2.6498 2.6005 1.4084 2.8075 2.40879972 NUP153 nucleoporin 153kDa 5.79889447E-06 2.56431268E-05 1.3327 1.4949 1.7176 1.4021 1.7260 2.7612 1.993911270 NRM nurim (nuclear envelope membrane protein) 5.44464609E-05 0.000197311728 1.3325 0.4996 0.5163 0.5931 0.4789 0.5948 0.63738220 DGCR14 DiGeorge syndrome critical region gene 14 6.37252104E-06 2.79095648E-05 1.3314 1.2840 2.1188 1.3234 1.2769 4.7345 1.792455702 CCDC94 coiled-coil domain containing 94 8.49532592E-07 4.49449649E-06 1.3313 1.6096 1.8609 1.3398 1.6072 1.6732 1.75482176 FANCC Fanconi anemia, complementation group C 0.00919216557 0.020093222799 1.3308 1.2710 0.9695 1.3417 1.4285 0.7134 1.42137329 UBE2I ubiquitin-conjugating enzyme E2I 5.94765225E-06 2.62121326E-05 1.3304 1.4527 1.1265 1.3429 1.2437 1.0191 1.488190324 CCDC97 coiled-coil domain containing 97 8.75546411E-07 4.6170228E-06 1.3303 3.0436 2.6445 3.0083 2.9316 3.1650 3.365455732 C1orf112 chromosome 1 open reading frame 112 0.0097640608 0.021183675962 1.3302 0.5303 0.2732 0.7742 0.7920 0.1905 0.619164965 MRPS9 mitochondrial ribosomal protein S9 1.13681721E-05 4.71446303E-05 1.3297 2.3708 3.8312 2.3216 2.3473 4.4756 2.4134103 ADAR adenosine deaminase, RNA-specific 8.39735713E-06 3.58580298E-05 1.3297 2.0006 2.7193 1.6656 1.7409 3.3988 1.855155346 TCP11L1 Q9NUJ3,B3KQZ4,t-complex 11, testis-specific-like 1 0.00873552161 0.019191469391 1.3297 0.7644 0.7463 1.0337 0.8637 1.3089 1.280984750 FUT10 fucosyltransferase 10 (alpha (1,3) fucosyltransferase) 0.01985723309 0.03919535088 1.3291 0.8659 1.1412 0.7044 0.7657 1.1983 0.753557827 C6orf47 chromosome 6 open reading frame 47 5.85053168E-06 2.58402018E-05 1.3288 0.5041 0.6701 0.5619 0.5527 0.8785 0.6067

54910 SEMA4C 0.00012761863 0.000428727256 1.3286 0.6563 0.8236 0.8999 0.4409 0.7393 0.86165860 QDPR quinoid dihydropteridine reductase 2.15090562E-05 8.42111581E-05 1.3271 2.1439 2.0623 2.0872 1.7473 1.9021 1.7249150383 CDPF1 similar to RIKEN cDNA 2210021J22 0.01320333526 0.027524397245 1.3263 1.1777 3.1551 2.0091 0.8858 3.5236 2.418711164 NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 1.74880776E-06 8.65967897E-06 1.3262 3.0692 10.3627 0.4585 1.7072 3.0165 0.2928675 BRCA2 breast cancer 2, early onset 0.00989480173 0.021436781736 1.3262 0.6209 0.7504 0.8008 0.8518 0.6629 0.986210951 CBX1 chromobox homolog 1 8.09836664E-06 3.4695432E-05 1.3260 1.2134 1.8218 1.6149 1.2763 2.1032 1.978684067 FAM160A2 family with sequence similarity 160, member A2 5.53077136E-05 0.000200075736 1.3251 1.7149 0.4389 1.4841 0.6295 1.4781 1.035856980 PRDM10 PR domain containing 10 0.00073941209 0.002107728195 1.3249 1.6098 1.1521 1.0811 1.3726 1.3577 1.052484187 TMEM164 transmembrane protein 164 1.92429114E-05 7.60723664E-05 1.3244 2.3228 3.0314 1.3988 1.7753 2.3687 1.5423150726 FBXO41 F-box protein 41 0.00024761141 0.000783167 1.3237 1.0585 0.8574 1.3114 0.5810 1.0543 1.073354509 RHOF ras homolog family member F (in filopodia) 7.71782072E-06 3.32437577E-05 1.3222 1.7900 2.3731 1.8315 1.2975 2.8599 2.71919120 SLC16A6 solute carrier family 16, member 6 0.02234703032 0.043420346455 1.3218 6.9983 3.5111 3.2993 4.3514 3.4232 1.89979578 CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.0136909767 0.028404851401 1.3217 0.9381 1.4864 0.4874 0.7469 0.8062 0.44152990 GUSB glucuronidase, beta 6.67266534E-05 0.000237759245 1.3215 1.6925 1.1604 1.8375 1.2598 1.6228 2.166023192 ATG4B autophagy related 4B, cysteine peptidase 1.15798886E-06 5.95183475E-06 1.3212 1.5699 5.0356 1.6206 0.6555 3.2025 0.701084100 ARL6 ADP-ribosylation factor-like 6 0.01859104115 0.037055686979 1.3202 1.8711 2.4695 1.9912 1.5513 2.7660 2.52285634 PRPS2 phosphoribosyl pyrophosphate synthetase 2 1.71850435E-06 8.52348302E-06 1.3197 0.7144 1.4875 0.7221 0.6864 2.7856 0.847910043 TOM1 target of myb1 (chicken) 1.90272748E-05 7.53006838E-05 1.3191 1.6401 1.3653 2.1665 1.4772 1.4226 2.522254991 C1orf159 chromosome 1 open reading frame 159 0.00216573146 0.005571201626 1.3187 1.0048 1.0324 0.6736 0.9907 0.9899 0.81195184 PEPD peptidase D 8.22396196E-07 4.36445637E-06 1.3185 0.9448 1.3168 0.8242 0.7480 1.0244 0.860164979 MRPL36 mitochondrial ribosomal protein L36 1.72579631E-05 6.89481314E-05 1.3173 2.0842 2.3598 1.4640 1.9608 2.6727 2.382623052 ENDOD1 endonuclease domain containing 1 4.06263736E-05 0.000150909758 1.3164 1.6088 2.4660 2.0482 1.5279 2.1559 2.016554897 CASZ1 castor zinc finger 1 0.0035423546 0.008648570713 1.3160 0.5619 2.1199 0.4918 0.5361 1.9384 0.62988139 GAN gigaxonin 0.0065630732 0.014932196927 1.3157 2.5741 2.7529 2.0955 2.3902 3.1357 2.6216203260 CCDC107 coiled-coil domain containing 107 0.02327581284 0.044976274566 1.3157 2.5530 11.2618 1.1589 0.7309 3.2642 0.684556479 KCNQ5 potassium voltage-gated channel, KQT-like subfamily, member 5 0.00377965403 0.00917034104 1.3152 2.1504 2.6490 2.2783 1.7701 3.3220 3.19608664 EIF3D eukaryotic translation initiation factor 3, subunit D 2.03392055E-05 7.99909519E-05 1.3149 1.1083 1.7366 1.2954 1.0371 1.9957 1.813779590 MRPL24 mitochondrial ribosomal protein L24 7.32902654E-05 0.000259096266 1.3131 1.7918 3.4462 1.7084 1.0859 4.3402 1.633780010 RMI1 RecQ mediated genome instability 1 0.00292830964 0.00730159304 1.3121 0.7343 2.7238 1.2829 0.3725 1.1222 0.46563241 HPCAL1 hippocalcin-like 1 2.52829611E-05 9.74415239E-05 1.3118 1.1974 1.5119 1.6415 1.0221 1.5186 1.550111070 TMEM115 transmembrane protein 115 1.55620293E-05 6.2742586E-05 1.3118 0.8836 1.8967 1.7911 0.8634 2.1103 2.176110226 PLIN3 perilipin 3 0.00058100689 0.001692087641 1.3113 1.2302 2.6180 1.6060 0.6669 2.3533 1.8110340037 PRR7-AS1 PRR7 antisense RNA 1 0.0218805093 0.042649953695 1.3112 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702067 ERCC1 excision repair cross-complementation group 1 8.69351781E-07 4.58832921E-06 1.3093 1.7851 2.0134 2.1570 1.2193 1.3674 1.7682

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C

20 ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00319026505 0.007881628321 1.3090 0.3280 0.6288 0.5730 0.2952 0.2797 0.5076128061 C1orf131 chromosome 1 open reading frame 131 0.00299722515 0.007460195877 1.3075 1.1859 0.2715 0.1156 0.4558 2.0078 0.175054801 HAUS6 HAUS augmin-like complex, subunit 6 8.91479841E-06 3.78464676E-05 1.3066 0.7937 0.9370 0.6458 0.9051 1.1917 0.9331116143 WDR92 WD repeat domain 92 0.02142730097 0.041905131478 1.3065 1.3079 10.6350 2.0700 0.6069 7.1029 1.573955148 UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 1.91960355E-06 9.41357917E-06 1.3062 0.5367 0.7462 0.9387 0.4623 1.9720 0.8216883 CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.02557197218 0.048768508057 1.3059 1.3379 5.0694 2.5887 0.4750 3.6967 3.287094120 SYTL3 synaptotagmin-like 3 0.00419464186 0.010075522019 1.3056 1.5925 2.2390 1.5643 1.1801 1.6426 1.0120738 VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) 2.68438942E-05 0.000102936335 1.3041 0.6338 0.5476 0.9518 0.7950 0.9305 1.07822801 GOLGA2 golgin A2 3.95626145E-06 1.80902926E-05 1.3030 0.4141 1.2888 1.0101 0.3550 2.0963 0.9994126295 ZNF57 zinc finger protein 57 0.02529581693 0.048337708327 1.3028 0.8944 1.4182 0.8688 0.9985 1.3312 1.270779652 TMEM204 transmembrane protein 204 0.00016353808 0.000535288918 1.3017 0.7151 1.9013 0.8666 0.6128 2.7296 1.2693166378 SPATA5 spermatogenesis associated 5 0.0004361112 0.001303980342 1.3012 4.8781 17.0891 9.4010 8.5567 3.9927 3.097327246 RNF115 ring finger protein 115 4.10731992E-05 0.000152445561 1.3003 2.3472 1.7868 1.7953 1.0071 1.1905 0.847080818 ZNF436 zinc finger protein 436 0.01311945695 0.027376564525 1.2999 2.5447 0.9539 2.8222 2.1195 0.8629 1.882026135 SERBP1 SERPINE1 mRNA binding protein 1 5.25795039E-06 2.34776224E-05 1.2999 1.9123 2.2886 1.7120 2.1506 5.4205 3.360022898 DENND3 DENN/MADD domain containing 3 0.01045515725 0.022461685276 1.2986 0.5350 0.6196 0.5957 0.4073 0.5024 0.75195605 MAP2K2 mitogen-activated protein kinase kinase 2 2.86325762E-05 0.000109176635 1.2984 0.9652 1.6353 1.3759 0.6286 1.7566 1.20404236 MFAP1 microfibrillar-associated protein 1 1.36920479E-06 6.93406593E-06 1.2981 1.9768 2.1924 1.6471 1.9804 3.2755 1.49401639 DCTN1 dynactin 1 5.84982013E-06 2.58402018E-05 1.2980 0.7682 0.7439 0.6010 0.5838 0.6461 0.627284335 AKT1S1 AKT1 substrate 1 (proline-rich) 0.00182905563 0.004779136912 1.2980 1.0705 2.1256 1.6763 1.0259 1.4708 1.87534846 NOS3 nitric oxide synthase 3 (endothelial cell) 0.00965509286 0.02096468885 1.2968 0.3050 0.5043 0.4196 0.2990 0.1637 0.408654948 MRPL16 mitochondrial ribosomal protein L16 1.70919706E-06 8.48192522E-06 1.2953 1.4215 1.7287 1.3286 1.5258 2.1907 1.293457001 ACN9 ACN9 homolog (S. cerevisiae) 0.00866678745 0.019056503054 1.2950 0.6469 0.2896 1.0637 0.6075 0.3566 0.79701528 CYB5A cytochrome b5 type A (microsomal) 0.00032647667 0.001006985424 1.2948 1.8693 1.6648 1.4677 2.1783 3.3180 2.22108672 EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 1.93176146E-05 7.63181521E-05 1.2945 0.3725 0.6338 0.5347 0.3273 0.7492 0.50129790 BMS1 BMS1 ribosome biogenesis factor 1.8506663E-06 9.10729183E-06 1.2940 1.8449 1.0762 1.7136 1.8764 1.9111 2.964922954 TRIM32 tripartite motif containing 32 0.00020348072 0.000653541873 1.2938 8.8222 4.4508 1.3985 2.5911 1.0357 0.636883752 LONP2 lon peptidase 2, peroxisomal 1.58865108E-06 7.93760802E-06 1.2931 1.7314 0.9882 1.4984 1.6880 1.1213 1.99663916 LAMP1 lysosomal-associated membrane protein 1 1.26733282E-05 5.20631239E-05 1.2930 1.7329 2.4496 1.9213 1.3220 2.1756 2.36905432 POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 7.25298045E-06 3.14043741E-05 1.2930 1.5025 2.5134 1.3289 1.0570 2.8936 1.6393219931 TPCN2 two pore segment channel 2 0.00274455133 0.006884739423 1.2928 0.7544 0.6154 1.1253 0.6452 0.4948 1.158184933 C8orf76 chromosome 8 open reading frame 76 0.02415764701 0.046517918241 1.2927 2.4924 2.5882 1.5044 1.8441 3.2946 1.856610921 RNPS1 RNA binding protein S1, serine-rich domain 2.97257427E-05 0.000113014725 1.2926 1.4242 2.1188 1.8843 1.1369 3.7093 3.197255847 CISD1 zinc finger, CDGSH-type domain 1 1.38605584E-05 5.64808482E-05 1.2918 1.9012 1.7865 1.4114 1.4077 2.0949 1.666854993 ZSCAN2 zinc finger and SCAN domain containing 2 0.01616995148 0.032810366848 1.2916 0.8769 1.4861 1.1417 0.9049 1.5640 1.178790957 DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 0.00015712674 0.000516835255 1.2915 3.2460 3.4018 0.5214 1.1538 1.8090 0.19029825 SPATA2 spermatogenesis associated 2 0.00018982066 0.000612900361 1.2906 1.2661 1.3516 1.3910 1.3968 1.8104 1.911710367 MICU1 mitochondrial calcium uptake 1 2.07386002E-05 8.14740277E-05 1.2904 0.8852 0.7736 0.7715 0.8126 0.6974 0.78273312 HSPA8 heat shock 70kDa protein 8 5.28787392E-05 0.000192011193 1.2902 3.1894 2.1212 2.7007 2.9859 3.0051 3.76441173 AP2M1 adaptor-related protein complex 2, mu 1 subunit 3.17373275E-05 0.000119963684 1.2890 0.9384 1.1158 0.9694 0.8647 1.0568 0.95245519 PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.00035486638 0.00108321393 1.2879 0.8748 1.1571 0.7013 0.7337 1.1219 0.81123163 HMOX2 heme oxygenase (decycling) 2 5.50564164E-06 2.44707089E-05 1.2875 1.9381 1.6959 1.3897 2.0782 2.0041 1.7389382 ARF6 ADP-ribosylation factor 6 1.94895535E-05 7.6914281E-05 1.2865 1.7921 2.1006 1.5507 1.9786 5.2121 2.692060526 C2orf43 chromosome 2 open reading frame 43 0.0006225398 0.001800989115 1.2863 2.3105 2.7317 1.4307 2.4424 3.3743 2.53125511 PPP1R8 protein phosphatase 1, regulatory subunit 8 2.42348789E-06 1.16134201E-05 1.2863 1.3856 1.2286 0.8830 1.5493 1.9420 1.449564841 GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 0.00090801583 0.002547798716 1.2862 1.8210 1.4263 1.1394 1.3407 1.6785 1.4852152002 XXYLT1 xyloside xylosyltransferase 1 0.00489523795 0.011551825893 1.2848 0.4618 0.8710 0.6886 0.4053 0.9560 0.731679863 RBFA ribosome binding factor A (putative) 7.04634683E-05 0.000249953115 1.2840 2.2277 4.6642 3.0777 1.3019 3.1851 1.62417319 UBE2A ubiquitin-conjugating enzyme E2A 3.63196982E-06 1.67668905E-05 1.2837 1.1166 0.7577 1.0650 0.9452 1.1854 1.16145431 POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 1.81075281E-05 7.20358704E-05 1.2833 1.8993 0.6817 0.9569 1.8355 1.0764 1.57896640 SNTA1 syntrophin, alpha 1 0.00633380927 0.014471847317 1.2826 1.4889 2.1862 2.1372 1.4182 1.7626 2.39098216 LZTR1 leucine-zipper-like transcription regulator 1 1.69290472E-06 8.40335643E-06 1.2808 0.7644 0.8065 1.0307 0.7340 1.0555 1.122492714 ARRDC1 arrestin domain containing 1 3.12061485E-06 1.45905513E-05 1.2808 0.9813 0.8879 0.8533 1.0301 1.5586 1.16718242 KDM5C lysine (K)-specific demethylase 5C 3.26051277E-05 0.000122913327 1.2808 1.4212 1.9890 2.0555 1.1679 4.3119 3.45084351 MPI mannose phosphate isomerase 0.00144519506 0.003875914301 1.2804 2.2910 1.6331 2.4479 2.1396 1.7108 2.448627102 EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 5.94210989E-06 2.61940246E-05 1.2802 1.3037 0.9667 0.9267 1.1444 0.8747 1.1884389 RHOC ras homolog family member C 0.01306028551 0.027271768743 1.2795 0.7918 1.5665 1.5107 0.5229 1.6571 1.317584896 ATAD1 ATPase family, AAA domain containing 1 1.05562175E-05 4.40916567E-05 1.2794 1.1508 1.8442 0.6969 0.9301 1.2224 0.37923482 IGF2R insulin-like growth factor 2 receptor 2.42031374E-05 9.35759049E-05 1.2793 1.8127 2.6321 1.7354 1.4862 2.3220 2.31228125 ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 2.35997468E-05 9.14947112E-05 1.2788 1.7844 1.9561 1.5528 1.9242 5.5922 3.305151621 KLF13 Kruppel-like factor 13 2.89510111E-05 0.000110321768 1.2787 0.7528 2.8008 0.7024 1.0100 4.0906 2.60218824 CES2 carboxylesterase 2 1.27569821E-05 5.23574972E-05 1.2783 5.7692 1.0086 0.8270 0.3367 2.0554 0.71336302 TSPAN31 tetraspanin 31 0.00581587846 0.013419337193 1.2775 1.5904 1.9442 1.4717 1.1609 1.8473 1.497511124 FAF1 Fas (TNFRSF6) associated factor 1 1.83175385E-06 9.0263771E-06 1.2773 1.1592 1.6747 1.0006 0.9614 2.1851 1.02171236 CCR7 chemokine (C-C motif) receptor 7 0.00356758 0.008704342616 1.2759 2.9194 2.7204 2.1162 2.8123 4.1604 2.4744

60468 BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.00041135059 0.001239478567 1.2757 1.3787 2.7294 1.4976 1.2006 1.8050 1.903955239 OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 1.91420556E-06 9.39214931E-06 1.2757 3.7528 2.5107 2.8810 3.3018 2.1397 1.872225880 TMEM186 transmembrane protein 186 0.00546471399 0.012705338331 1.2755 1.0762 9.4947 1.6807 0.6627 4.3921 1.599853834 FGFRL1 fibroblast growth factor receptor-like 1 0.00122717959 0.003345222362 1.2754 1.2799 1.5108 1.9197 0.8531 1.6283 1.68175467 PPARD peroxisome proliferator-activated receptor delta 2.16243505E-05 8.45987388E-05 1.2751 1.0855 1.7803 1.3900 0.7907 1.2042 1.2193153830 RNF145 ring finger protein 145 1.65795499E-05 6.65659273E-05 1.2747 2.2640 2.9353 1.8681 2.1266 4.1390 2.030923039 XPO7 exportin 7 2.12268222E-06 1.02934314E-05 1.2746 2.2097 2.1449 1.8796 1.3172 1.4438 1.39295037 PEBP1 phosphatidylethanolamine binding protein 1 3.49318382E-05 0.000131197235 1.2738 2.4536 3.0971 1.8259 2.2245 5.7960 2.22057701 ZNF142 zinc finger protein 142 3.49224223E-06 1.61831727E-05 1.2730 0.8091 1.6997 1.2945 0.4099 1.4887 0.8485

9551 ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 1.07493777E-05 4.48533064E-05 1.2727 0.3321 0.3321 0.3321 0.3970 0.3970 0.397010403 NDC80 NDC80 kinetochore complex component 0.0015763831 0.004190587904 1.2716 2.8820 2.8276 3.4415 0.3983 1.8084 3.6720224 ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00013191406 0.000441049155 1.2715 1.1806 1.5843 0.9873 1.1205 1.7582 1.109993973 ACTR8 ARP8 actin-related protein 8 homolog (yeast) 5.46822899E-05 0.000198009275 1.2709 1.0658 1.0091 0.9021 1.0159 1.2860 0.88033068 HDGF hepatoma-derived growth factor 3.95971619E-05 0.000147506492 1.2703 1.8163 1.5890 1.7324 1.6988 1.7845 1.701311260 XPOT exportin, tRNA 0.00013084634 0.000438040355 1.2691 2.2371 2.6109 1.8621 2.4522 3.3425 2.83323981 LIG4 ligase IV, DNA, ATP-dependent 0.02175132682 0.042434362976 1.2685 0.6156 1.5017 1.2420 0.5633 1.1547 0.77887564 ZNF16 zinc finger protein 16 0.02102439334 0.041231911026 1.2677 1.7798 1.4949 1.7968 1.6919 2.1808 1.685163906 GPATCH3 G patch domain containing 3 0.00056960109 0.001662049054 1.2675 3.3821 3.4381 2.3218 3.1889 5.4011 2.8630729967 MORN2 hypothetical protein LOC729967 0.02236909612 0.043458599071 1.2673 0.3441 0.1454 0.3773 0.9133 0.1121 0.72952040 STOM stomatin 0.00822474971 0.018213868219 1.2669 1.6086 2.3608 2.1201 1.4575 3.1121 2.442655915 LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 0.00318532108 0.007870478253 1.2659 1.1457 1.3532 1.4291 1.1981 2.4677 2.3121377 ARF3 ADP-ribosylation factor 3 3.5808615E-05 0.000134241898 1.2657 1.1349 2.9634 1.5937 0.8010 5.0981 1.79476051 RNPEP arginyl aminopeptidase (aminopeptidase B) 3.04982566E-05 0.000115686972 1.2655 1.5077 1.2462 1.5983 0.9681 1.5979 2.227851368 TEX264 testis expressed 264 2.81818639E-06 1.32921791E-05 1.2655 1.4936 1.5883 2.3082 0.8945 1.5857 2.515523042 PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 3.61290515E-06 1.66873111E-05 1.2654 1.8486 1.4152 1.4134 1.5538 2.1324 2.13508799 PEX11B peroxisomal biogenesis factor 11 beta 1.95857093E-05 7.72437041E-05 1.2637 2.4096 1.9728 2.1238 1.9307 2.5290 2.703856905 C15orf39 chromosome 15 open reading frame 39 0.00017969765 0.000583203464 1.2635 0.7428 0.9030 1.2597 0.6035 0.9436 1.257826001 RNF167 ring finger protein 167 1.1848452E-05 4.898075E-05 1.2633 2.5281 2.8333 2.3242 1.4400 2.3519 1.75095034 P4HB prolyl 4-hydroxylase, beta polypeptide 0.00021575401 0.000689326344 1.2627 0.8356 1.2053 1.1213 0.9228 2.3028 1.94365589 PRKCSH protein kinase C substrate 80K-H 4.90116754E-05 0.000178965095 1.2621 0.7087 1.6578 3.8176 0.6515 2.4473 2.168358497 PRUNE prune exopolyphosphatase 0.00017634187 0.000573228722 1.2618 0.9920 18.3189 0.7821 0.7048 16.4484 0.286880227 PAAF1 proteasomal ATPase-associated factor 1 0.00134459062 0.003631864396 1.2617 1.3761 1.6254 1.7262 0.4622 3.4291 0.570423119 HIC2 hypermethylated in cancer 2 0.00214417582 0.005521970483 1.2613 1.2106 0.6292 1.0928 0.9540 0.8894 1.13685437 POLR2H polymerase (RNA) II (DNA directed) polypeptide H 7.76903113E-05 0.000273728764 1.2611 1.7124 2.2486 1.8830 1.8394 2.5142 2.36231022 CDK7 cyclin-dependent kinase 7 0.00138316638 0.003723219807 1.2611 2.7022 2.1196 1.2490 3.0591 1.9235 2.054523438 HARS2 histidyl-tRNA synthetase 2, mitochondrial 3.53034946E-05 0.000132484176 1.2611 0.9778 0.7216 1.0624 0.7636 0.7889 0.87821774 DNASE1L1 deoxyribonuclease I-like 3 0.01071835735 0.022956959976 1.2606 0.8581 0.6090 0.8937 0.8073 0.3433 0.625651665 ASB1 ankyrin repeat and SOCS box containing 1 2.52004E-06 1.20287803E-05 1.2606 2.7433 2.0741 1.6032 2.2535 3.0859 2.285327040 LAT linker for activation of T cells 4.87892858E-05 0.000178305053 1.2596 1.0493 2.2669 1.7263 1.5168 2.6880 2.218255775 TDP1 tyrosyl-DNA phosphodiesterase 1 3.03597666E-06 1.4231238E-05 1.2587 0.9867 0.7736 1.1437 0.8634 0.9978 1.104196764 TGS1 trimethylguanosine synthase 1 1.9689656E-06 9.6272249E-06 1.2584 21.9824 4.1891 1.1419 17.1236 1.3947 0.514380128 TRIM46 tripartite motif containing 46 0.02495271691 0.047787028959 1.2582 0.8666 0.8947 1.1574 0.4579 0.7502 0.706164098 PARVG parvin, gamma 0.00489964611 0.01155775029 1.2575 0.9872 1.1140 1.0253 1.0152 1.2339 0.9770375035 SFT2D2 SFT2 domain containing 2 0.00614153637 0.014078302925 1.2560 0.3321 0.3321 0.3321 0.3970 0.3970 0.397010845 CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.74150914E-05 6.94930224E-05 1.2558 1.4281 1.6796 1.6580 1.2974 3.1850 2.57598492 PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 0.02278154847 0.04416581402 1.2548 1.1905 2.8968 1.4563 1.1166 1.4572 1.4354221955 DAGLB diacylglycerol lipase, beta 0.00131455285 0.003561083711 1.2547 0.7321 1.0651 0.7180 0.8047 1.2313 0.924993183 PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.01262717621 0.026480404429 1.2536 2.4392 2.6721 1.8105 2.1488 2.9749 2.185485028 SNHG12 small nucleolar RNA host gene 12 (non-protein coding) 0.02430000816 0.046747709951 1.2533 3.4650 2.3371 2.2736 1.6148 2.0566 2.2735201254 STRA13 stimulated by retinoic acid 13 homolog (mouse) 0.00098823922 0.002750092463 1.2531 0.8996 1.3009 3.6771 0.6522 1.2115 2.555579631 EFTUD1 elongation factor Tu GTP binding domain containing 1 0.00080306955 0.002275342983 1.2524 1.4538 0.1214 1.3441 0.2230 0.1529 0.671164434 NOM1 nucleolar protein with MIF4G domain 1 5.10435199E-05 0.000185827295 1.2517 1.6588 2.8642 1.8340 1.1404 6.3959 2.42606683 SPAST spastin 0.00063836509 0.001840651248 1.2517 2.1468 3.1263 1.9657 2.3516 2.8706 2.877822976 PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.00282145638 0.007060209673 1.2514 0.9234 0.7135 1.0206 0.4112 0.7949 0.917055161 TMEM33 transmembrane protein 33 5.85526699E-05 0.000210854234 1.2511 1.9632 1.2016 1.4583 2.4888 2.1706 2.1410196463 PLBD2 phospholipase B domain containing 2 0.00244395735 0.006212574947 1.2506 1.3732 2.4977 1.6551 1.3552 2.9104 2.06487307 U2AF1 U2 small nuclear RNA auxiliary factor 1 5.12452702E-05 0.000186487468 1.2502 1.9015 2.7253 2.0698 1.5374 2.9414 1.9759

9014 TAF1B 0.00484293654 0.011440224491 1.2499 1.3839 1.2459 1.8392 1.3431 2.1044 2.0093115704 EVI5L ecotropic viral integration site 5-like 0.00180218289 0.004714989359 1.2495 0.6257 1.0334 0.5484 0.4408 0.5338 0.55289675 TTI1 TELO2 interacting protein 1 6.61508506E-05 0.00023584553 1.2489 3.5499 1.7508 1.9225 3.0292 0.8519 1.1101148789 B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 0.00704291432 0.015877622502 1.2483 1.9342 3.8035 1.6395 1.6599 6.4071 2.8010252969 NEIL2 nei like 2 (E. coli) 0.00213221533 0.005497366791 1.2480 1.9919 2.2170 2.1956 1.5109 2.3365 3.1686113730 KLHDC7B kelch domain containing 7B 0.00434144085 0.010379014411 1.2480 1.2035 2.0949 1.7545 0.7346 1.7116 2.0387221785 ZSCAN25 zinc finger protein 498 5.13141386E-06 2.29525567E-05 1.2476 1.2746 1.2196 1.5712 1.3028 1.9524 1.743179649 MAP7D3 MAP7 domain containing 3 0.00037838477 0.001148479487 1.2459 1.4849 0.7671 0.6393 0.8647 1.0362 0.93986100 RP9 retinitis pigmentosa 9 (autosomal dominant) 0.01516825361 0.031064148161 1.2454 1.9200 3.9202 2.1976 1.4661 3.1203 2.63501889 ECE1 thymidine phosphorylase 5.90042222E-05 0.00021222936 1.2447 1.6901 2.3415 1.9173 1.1634 2.3025 1.751684197 POMK protein-O-mannose kinase 0.0219492236 0.042751968185 1.2436 2.3038 4.5519 1.7737 2.3822 5.9779 2.410091942 NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 0.00943948299 0.020564949701 1.2435 3.4868 1.6743 3.6448 3.1449 0.8112 3.09899836 LCMT2 leucine carboxyl methyltransferase 2 0.00038093797 0.001154886119 1.2432 1.4769 0.3839 2.0627 0.9667 0.5898 1.639484888 SPPL2A signal peptide peptidase like 2A 3.37376133E-05 0.000126894539 1.2432 2.0473 2.5543 2.1086 1.8666 3.2648 2.629425844 YIPF3 Yip1 domain family, member 3 4.14690985E-06 1.88629168E-05 1.2429 1.7258 1.2141 1.1473 0.2263 0.5247 0.371510352 WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 0.00249511358 0.006325893613 1.2428 1.8889 3.3206 1.8297 1.7016 3.2663 2.067680148 PQLC1 PQ loop repeat containing 1 2.89979077E-06 1.36453713E-05 1.2427 2.4085 5.5969 1.9228 1.4255 4.3607 2.162210522 DEAF1 DEAF1 transcription factor 3.74971969E-06 1.72538097E-05 1.2414 0.5077 1.4445 0.7897 0.9642 0.5808 0.826655110 MAGOHB mago-nashi homolog B (Drosophila) 0.00550450291 0.012788083561 1.2413 2.4054 1.4756 1.4987 2.2389 2.0522 2.0265

TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa

10400 PEMT phosphatidylethanolamine N-methyltransferase 0.00215820463 0.005553403032 1.2413 0.7189 0.6576 0.7661 0.6604 0.8986 1.102557819 LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.96729E-05 0.0001128373 1.2407 0.6476 0.5519 0.6069 0.6283 0.6052 0.59585706 PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 9.36213558E-06 3.95708863E-05 1.2406 1.2284 1.2164 1.1761 1.2104 1.3991 1.48274152 MBD1 methyl-CpG binding domain protein 1 7.32233964E-06 3.16821667E-05 1.2398 0.8087 1.2984 1.2830 0.9682 1.4820 1.2997124401 ANKS3 ankyrin repeat and sterile alpha motif domain containing 3 0.01423297837 0.029382553472 1.2395 0.4670 0.6500 0.8024 0.0667 0.8306 0.4063613 BCR breakpoint cluster region 3.27457133E-05 0.000123341512 1.2395 0.7261 0.8439 1.0103 0.4864 0.7282 0.7307

85365 ALG2 0.00011565694 0.000391856764 1.2362 3.7650 8.7958 2.2819 2.5723 7.0275 2.226355974 SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 1.03092977E-05 4.32044697E-05 1.2360 2.2543 1.7533 2.3475 1.9367 2.7749 3.31149604 RNF14 ring finger protein 14 0.0014466987 0.003879377558 1.2355 1.5344 1.2281 1.0230 1.3323 1.4340 0.964326037 SIPA1L1 signal-induced proliferation-associated 1 like 1 6.21062163E-06 2.72462133E-05 1.2351 0.3364 0.3180 0.4042 0.3441 0.3020 0.29461938 EEF2 ephrin-A1 4.43672664E-06 2.0076243E-05 1.2346 2.6188 2.2357 2.0803 1.9298 3.1648 2.53578540 AGPS alkylglycerone phosphate synthase 3.14941942E-06 1.47064124E-05 1.2325 3.1024 2.0844 1.8451 1.1923 0.8583 0.9093150275 CCDC117 coiled-coil domain containing 117 1.50393665E-05 6.07828588E-05 1.2313 2.1223 3.6849 1.1336 1.4944 4.4795 1.7247124245 ZC3H18 zinc finger CCCH-type containing 18 3.56573376E-06 1.64777661E-05 1.2301 0.5815 0.8263 0.7312 0.4343 1.1553 0.7810835 CASP2 caspase 2, apoptosis-related cysteine peptidase 6.01086088E-06 2.64524205E-05 1.2301 1.6031 1.1708 1.2865 1.3625 1.3605 1.32238705 B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 0.016991529 0.034249224266 1.2286 0.4976 0.7552 0.7041 0.5087 0.7722 0.704792105 INTS4 integrator complex subunit 4 1.10640824E-05 4.60193293E-05 1.2276 2.6341 1.8971 2.4601 2.6627 2.4089 2.5054118813 ZFYVE27 zinc finger, FYVE domain containing 27 5.01590728E-05 0.000182898938 1.2273 1.8321 1.5898 1.5920 1.4516 1.2234 1.47472475 MTOR mechanistic target of rapamycin (serine/threonine kinase) 4.51145456E-06 2.037906E-05 1.2271 1.4329 1.1305 1.0277 1.1490 1.2491 1.018553407 STX18 syntaxin 18 0.00092193232 0.002582880599 1.2261 2.1721 0.7666 6.6649 3.7842 0.4395 1.78703418 IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00138682999 0.003730883045 1.2258 1.4896 2.5088 2.1503 1.1250 2.4114 1.6737114034 TOE1 target of EGR1, member 1 (nuclear) 0.00093434094 0.002614037312 1.2257 1.3052 1.4740 0.3699 0.5494 0.7711 0.447510540 DCTN2 dynactin 2 (p50) 3.18350414E-05 0.000120283267 1.2256 1.8186 1.3446 1.4907 1.5439 1.7058 1.914565980 BRD9 bromodomain containing 9 0.00016505881 0.000540009769 1.2249 0.3445 0.5570 0.6926 0.2490 0.5916 0.663159349 KLHL12 kelch-like family member 12 4.3911776E-06 1.98947674E-05 1.2249 0.4662 0.5574 0.6243 0.6178 0.5778 0.6782808 CALM3 calmodulin 3 (phosphorylase kinase, delta) 2.28548243E-05 8.89843065E-05 1.2248 2.0160 4.9957 1.9592 1.6479 9.2691 2.39818508 NIPSNAP1 nipsnap homolog 1 (C. elegans) 1.01569193E-05 4.26441243E-05 1.2245 1.1388 2.3792 1.2551 1.5805 2.3555 1.871826099 SZRD1 SUZ RNA binding domain containing 1 8.16966263E-05 0.000286518379 1.2235 1.2255 1.9730 0.8758 1.6611 3.3517 1.796526123 TCTN3 tectonic family member 3 0.00026394396 0.000830941423 1.2234 1.6819 2.0839 1.9728 1.3927 3.4022 1.69212782 GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 5.36152742E-05 0.000194608322 1.2232 1.0655 2.3973 1.4494 1.4288 4.8303 2.845355734 ZFP64 ZFP64 zinc finger protein 0.00799044523 0.01775309037 1.2226 1.4358 1.6854 1.7757 1.2569 1.5871 1.7416153527 ZMAT2 zinc finger, matrin-type 2 6.94614192E-06 3.01974554E-05 1.2223 2.1791 0.8123 1.8550 1.9876 0.7901 1.9533126308 MOB3A MOB kinase activator 3A 8.45779321E-05 0.000295602138 1.2216 2.2253 3.4359 1.7132 2.5590 4.9698 2.060655858 TMEM165 transmembrane protein 165 0.00033850143 0.001039337626 1.2207 2.2414 2.0030 1.8820 1.5712 2.8334 2.71243685 ITGAV integrin, alpha V 0.00249019764 0.006316059309 1.2204 1.2726 1.2838 1.2570 1.3056 1.4646 1.561955149 MTPAP mitochondrial poly(A) polymerase 0.00015056096 0.000497027964 1.2197 1.8324 0.8050 1.2158 2.0238 1.3583 1.185379672 FN3KRP fructosamine 3 kinase related protein 0.00028943947 0.000902343965 1.2196 1.4916 2.9112 1.8997 1.3469 3.4360 2.1537784 CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.0218200829 0.042541245706 1.2192 0.9501 1.1369 1.7280 0.9053 1.1278 1.8700476 ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00148467328 0.003972463047 1.2190 1.1198 1.8039 1.0523 0.9825 1.6933 1.09955438 POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 2.18268331E-05 8.532732E-05 1.2190 4.8656 1.1827 5.0362 3.6461 0.8788 4.508855229 PANK4 pantothenate kinase 4 1.09415494E-05 4.55615294E-05 1.2174 1.2910 2.6574 2.3060 0.9027 2.2338 2.6026552900 BOLA2 bolA homolog 2 (E. coli) 8.57328261E-05 0.00029923786 1.2158 0.3321 0.3321 0.3321 0.3970 0.3970 0.397091966 CXorf40A chromosome X open reading frame 40A 0.00028796634 0.000898057856 1.2157 0.2734 0.2298 1.4682 0.7927 0.2022 0.83868761 PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 8.11974925E-05 0.000285041418 1.2152 2.2932 1.8988 0.8560 1.9767 2.3119 1.606423195 MDN1 MDN1, midasin homolog (yeast) 0.00048181583 0.00142732471 1.2128 1.3227 1.2733 0.9826 1.5482 2.0829 1.45812870 GRK6 G protein-coupled receptor kinase 6 9.13345943E-05 0.000316312681 1.2122 1.3538 3.3915 2.6707 1.0107 2.6574 2.388993100 NAPRT1 nicotinate phosphoribosyltransferase domain containing 1 4.38087457E-05 0.000161711798 1.2118 1.1089 2.2113 1.2604 0.6406 2.2120 1.773926229 B3GAT3 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) 5.04869726E-06 2.26213331E-05 1.2118 1.9484 2.1990 1.4962 1.0125 3.0018 1.462584271 POLDIP3 polymerase (DNA-directed), delta interacting protein 3 2.20843967E-05 8.62419526E-05 1.2117 2.1545 2.2458 0.8182 1.0166 4.1720 1.256484365 MKI67IP MKI67 (FHA domain) interacting nucleolar phosphoprotein 0.00047952836 0.001421009111 1.2109 2.5497 1.2691 1.8700 2.2167 2.2417 2.06873183 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1.76891848E-05 7.04943912E-05 1.2105 1.5532 1.2174 1.2223 1.1485 1.5479 1.069711243 PMF1 polyamine-modulated factor 1 5.48944884E-06 2.44225004E-05 1.2099 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

160622 GRASP 0.02199762632 0.042823420845 1.2093 0.4662 1.1977 0.8938 0.4367 1.1776 0.872551143 DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 1.10582493E-05 4.60055399E-05 1.2092 1.6324 1.6000 1.4713 1.4254 1.6303 2.1631

515 ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 8.98254627E-05 0.000311763528 1.2079 1.0135 4.6101 1.7329 0.6241 1.9941 1.035125804 LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00020052018 0.000644713141 1.2074 1.7216 1.7293 2.5250 1.1685 3.0448 2.2479203259 FAM219A chromosome 9 open reading frame 25 0.00044657598 0.001332000691 1.2069 2.7004 2.0370 1.0114 1.9166 2.1063 1.27031021 CDK6 cyclin-dependent kinase 6 0.00375415638 0.009116951792 1.2065 1.6452 2.4372 1.7067 1.4642 3.5313 2.954025904 CNOT10 CCR4-NOT transcription complex, subunit 10 8.56736582E-05 0.000299088476 1.2065 1.0822 0.8886 0.8163 0.9324 1.1392 0.96671788 DNMT3A DNA (cytosine-5-)-methyltransferase 3 beta 2.07200131E-05 8.14185118E-05 1.2055 0.8269 1.4051 1.4263 0.7148 1.7081 1.314823173 METAP1 methionyl aminopeptidase 1 5.69437681E-06 2.52175601E-05 1.2053 0.6433 0.8331 0.8370 0.7302 0.7580 1.137979866 BORA chromosome 13 open reading frame 34 0.01883601099 0.037483292624 1.2025 1.1500 4.9368 1.6605 0.4258 5.9574 0.63885162 PDHB pyruvate dehydrogenase (lipoamide) beta 6.11924433E-06 2.68711445E-05 1.2024 2.0136 1.7873 1.3917 1.5718 1.8962 1.781392255 LMBRD2 LMBR1 domain containing 2 0.01858505335 0.037048450237 1.2020 2.4405 3.9100 4.2114 1.5008 1.8954 2.283579786 KLHL36 kelch-like family member 36 1.44903473E-05 5.87849969E-05 1.2006 1.4074 1.1718 1.1414 1.1476 1.5308 1.1901389906 LOC389906 zinc finger protein 839 pseudogene 0.00672224181 0.015244979802 1.2005 1.5934 1.6468 0.9986 0.8713 2.4609 2.17128797 TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.00075599915 0.002152995082 1.2002 10.2026 8.5874 1.2383 9.0355 8.1279 3.01185685 PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 5.91308499E-05 0.00021260112 1.1995 2.5703 2.4705 1.8795 2.6547 4.2577 2.7814

84901 NFATC2IP 1.01850862E-05 4.27525604E-05 1.1987 0.7221 1.3427 0.9301 0.9264 1.1633 1.787427433 TOR2A torsin family 2, member A 0.00077425342 0.002200180183 1.1977 1.3926 0.5972 1.0500 0.9672 0.6787 1.586192799 SHKBP1 SH3KBP1 binding protein 1 9.29370911E-05 0.000321314386 1.1977 0.8674 1.2277 1.0639 0.7857 1.3372 0.97649733 SART3 squamous cell carcinoma antigen recognized by T cells 3 3.11656258E-05 0.000117997993 1.1976 1.0916 0.9313 0.8646 1.3422 2.2412 1.47919818 NUPL1 nucleoporin like 1 0.00015866498 0.000521519433 1.1975 1.5165 1.6494 1.4602 1.8826 2.4508 1.706725839 COG4 component of oligomeric golgi complex 4 1.23551595E-05 5.08912249E-05 1.1970 0.8487 1.1408 2.8768 0.7995 0.2533 2.100679003 MIS12 MIS12 kinetochore complex component 0.00096405379 0.002688110928 1.1967 2.0638 8.5240 1.8458 0.6476 4.0339 1.25316627 SNRPA1 small nuclear ribonucleoprotein polypeptide A' 0.00206574242 0.00534105638 1.1964 1.7525 2.8353 1.7422 1.7934 4.3142 2.73048803 SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.00043003355 0.001287493534 1.1960 1.1900 2.3886 2.1164 0.8398 1.9354 1.5434260294 NSUN5P2 NOL1/NOP2/Sun domain family, member 5C 0.02489194743 0.047695644231 1.1954 0.8124 1.1025 1.0822 0.7283 1.1940 0.993984280 BTBD10 BTB (POZ) domain containing 10 0.00319914013 0.00790141775 1.1948 1.4979 1.6772 1.1514 1.2697 2.1393 1.44053274 HRH2 histamine receptor H2 0.0074866212 0.016753893761 1.1946 0.8286 1.2539 1.3043 0.7779 1.1366 1.235122994 AZI1 centrosomal protein 131kDa 0.00998358776 0.021600784521 1.1935 0.4579 0.4295 0.8071 0.3024 0.3232 0.997818 ABAT 4-aminobutyrate aminotransferase 0.00316059367 0.007819812468 1.1935 0.5038 0.5564 0.6445 0.3895 0.5785 0.7153146705 ENTHD2 ENTH domain containing 2 0.0028392066 0.007098141094 1.1925 0.9281 1.3371 0.8041 0.6399 0.4646 0.672260412 EXOC4 exocyst complex component 4 9.87530196E-06 4.15476669E-05 1.1923 0.6829 0.8955 0.5127 0.5906 1.1091 0.597356945 MRPS22 mitochondrial ribosomal protein S22 5.56123625E-05 0.000201137983 1.1916 1.7243 2.0057 1.1386 2.0465 3.3040 1.4964644 BLVRA biliverdin reductase A 0.00014479837 0.000480522299 1.1904 1.9850 2.7678 1.3313 1.3694 2.3813 1.476510465 PPIH peptidylprolyl isomerase H (cyclophilin H) 2.5407785E-05 9.78606763E-05 1.1900 2.5850 1.9553 2.1604 2.1870 3.5738 2.21159711 KIAA0226 KIAA0226 1.21788677E-05 5.02216815E-05 1.1899 0.7502 0.9859 0.8141 0.7165 1.2017 1.0215

127428 TCEANC2 0.01630709728 0.033055611435 1.1898 0.3321 0.3321 0.3321 0.3970 0.3970 0.39705902 RANBP1 RAN binding protein 1 0.00168029415 0.004434830966 1.1886 1.2028 1.5284 1.5168 0.8021 3.2962 1.3086790955 C11orf83 hypothetical protein LOC790955 0.00010924783 0.000372282045 1.1883 0.2651 9.1128 2.2559 0.0158 3.2556 1.4657129563 DIS3L2 DIS3 mitotic control homolog (S. cerevisiae)-like 2 0.00106624645 0.002945193507 1.1879 0.9305 0.9142 1.1288 1.0173 1.2608 1.574991289 LMF2 lipase maturation factor 2 1.3098409E-05 5.36383078E-05 1.1879 1.5428 5.0783 1.9029 0.6102 14.2345 1.827551222 ZNF219 zinc finger protein 219 0.01387479356 0.028743790006 1.1867 1.3465 1.9102 1.5106 1.0066 2.1268 1.308684247 LDOC1L leucine zipper, down-regulated in cancer 1-like 0.00350732539 0.008580244938 1.1866 1.5628 2.2636 1.9595 1.0818 2.4093 1.780610605 PAIP1 poly(A) binding protein interacting protein 1 2.02897364E-05 7.98135768E-05 1.1866 1.9535 1.3415 1.7002 1.6636 2.8961 2.384423293 SMG6 SMG6 nonsense mediated mRNA decay factor 2.84614813E-05 0.000108614909 1.1865 2.6333 1.4734 2.0702 1.8890 0.9945 1.211354681 P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.00010938137 0.000372598132 1.1853 0.5080 1.9065 1.0551 0.5771 3.5143 1.4622113763 ZBED6CL ZBED6 C-terminal like 0.02580177863 0.049150343941 1.1842 0.1113 0.2225 0.1246 0.1369 0.4754 0.22622889 RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.00012996535 0.000435649774 1.1840 0.8939 1.0079 1.2177 0.5514 1.1125 0.8095131474 CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 0.00376890908 0.009149130689 1.1837 5.1715 12.0382 2.1430 2.7987 17.8571 1.43878703 B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 1.52174025E-05 6.14480395E-05 1.1832 1.3324 1.2513 1.1840 1.4952 1.4469 0.99717884 SLBP stem-loop binding protein 5.89074231E-05 0.000211922905 1.1830 1.8838 2.1793 1.5196 1.7936 3.9331 3.223510678 B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 4.05546046E-05 0.000150673798 1.1829 1.5912 1.8613 1.2385 1.9356 3.3429 2.073184886 C1orf198 chromosome 1 open reading frame 198 0.01657406248 0.033514970089 1.1828 0.7018 0.7067 0.5971 0.6700 0.9022 0.705655630 SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.00120112301 0.003283992169 1.1818 0.5063 0.3300 0.6690 0.3616 0.4979 0.843580306 MED28 mediator complex subunit 28 9.44084977E-06 3.98666991E-05 1.1813 2.7227 1.8293 1.8860 3.1410 3.6222 3.25438270 LAGE3 L antigen family, member 3 8.58897028E-06 3.66248927E-05 1.1807 1.5392 1.5012 1.8719 0.7624 1.8520 1.963710531 PITRM1 pitrilysin metallopeptidase 1 1.14654531E-05 4.75157086E-05 1.1803 1.3708 1.8657 1.6454 1.5338 2.0474 2.61982739 GLO1 glyoxalase I 2.29759311E-05 8.93606244E-05 1.1803 0.9798 1.5868 1.1650 0.9097 1.9830 1.239623125 CAMTA2 calmodulin binding transcription activator 2 4.80004407E-05 0.000175623559 1.1796 0.9318 1.5820 1.4645 0.9016 2.0612 1.6709115362 GBP5 guanylate binding protein 5 0.01761446176 0.035372177752 1.1791 2.3718 3.1371 1.0371 2.5955 3.7258 2.044591 ACVR1B activin A receptor, type IB 0.00216870675 0.005576500109 1.1784 1.8302 2.3932 2.0389 1.1952 1.5674 1.424991304 TMEM259 transmembrane protein 259 7.38893985E-05 0.000261092069 1.1779 0.9210 0.7888 1.1570 0.7391 1.7073 1.3324780 DDR1 discoidin domain receptor tyrosine kinase 1 0.02430439766 0.046751232127 1.1773 0.3620 0.3612 0.3649 0.3976 0.3674 0.40652937 GSS glutathione synthetase 1.02370629E-05 4.29510021E-05 1.1765 0.1700 0.3851 0.8714 0.2517 0.2289 0.56685711 PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 1.71461463E-05 6.855457E-05 1.1761 0.3020 2.6244 0.6004 0.0913 3.3268 0.18407030 TFE3 transcription factor binding to IGHM enhancer 3 1.91592677E-05 7.57908941E-05 1.1747 2.0721 1.1275 2.3053 1.0793 1.1834 2.7310388152 LOC388152 golgin A2 pseudogene 0.00545132643 0.012682281188 1.1739 2.1910 1.6618 1.6262 1.3886 1.2524 1.66224677 NARS asparaginyl-tRNA synthetase 0.00131872492 0.003570797523 1.1736 1.5073 2.0898 1.7847 1.9442 3.0822 2.725784138 SLC7A6OS solute carrier family 7, member 6 opposite strand 0.0164367083 0.033270359376 1.1735 0.3741 2.7586 3.7235 1.1689 1.3709 0.890480344 DCAF11 WD repeat domain 23 4.80507284E-05 0.000175772354 1.1734 3.1278 6.2505 2.0273 2.4434 5.0866 2.4464127253 TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) 0.00078138255 0.002217679694 1.1731 4.9809 8.2916 2.7910 1.7719 0.9260 1.199410623 POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 0.00018079069 0.000586334323 1.1730 1.2307 6.6514 2.1442 0.7188 5.2350 1.557457470 LRRC47 leucine rich repeat containing 47 1.32961945E-05 5.44116607E-05 1.1730 2.3380 1.7180 2.2626 1.6760 2.3162 2.571454480 CHPF2 chondroitin polymerizing factor 2 3.16740382E-05 0.00011974923 1.1726 1.9450 1.6103 1.5840 1.3393 2.8739 2.04332787 GNG5 guanine nucleotide binding protein (G protein), gamma 5 1.3344092E-05 5.45954431E-05 1.1717 1.7462 2.0359 1.8290 2.2956 2.9345 3.475857701 NCKAP5L NCK-associated protein 5-like 0.00545659686 0.012691310813 1.1714 0.5721 18.3869 0.4147 0.7318 3.1342 0.679955794 DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 1.14388823E-05 4.74163471E-05 1.1713 0.8350 0.8214 1.4471 0.5502 0.6666 0.77575898 RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.00013388572 0.000447068703 1.1710 1.7968 2.5817 1.8860 1.8213 3.7609 2.86173718 JAK3 Janus kinase 3 0.00011876237 0.000401633534 1.1706 2.8967 2.3270 2.5912 2.7614 2.9265 2.222780013 FAM188A family with sequence similarity 188, member A 0.02361368755 0.045571324353 1.1698 2.1683 3.4653 1.6966 2.5214 3.0730 2.5883201266 SLC39A11 solute carrier family 39 (metal ion transporter), member 11 0.004617797 0.010970795323 1.1683 2.2733 2.3106 2.4319 1.2314 1.5432 2.04155914 RARA retinoic acid receptor, alpha 4.73176614E-05 0.000173403191 1.1678 1.5806 1.6359 1.4863 1.0191 1.3249 1.197551651 PTRH2 peptidyl-tRNA hydrolase 2 0.00034669127 0.001061985401 1.1670 1.8204 0.3286 1.9800 0.3148 1.0424 0.332529980 DONSON downstream neighbor of SON 0.00234584655 0.005985659572 1.1666 0.6204 0.6737 0.5892 0.6182 0.5051 0.6325339122 RAB43 RAB43, member RAS oncogene family 0.00988463725 0.021419840112 1.1654 0.7058 1.0574 0.9017 0.9975 2.0725 1.237279873 NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 0.00177571316 0.004654401205 1.1649 1.2790 0.8172 1.1735 1.3540 1.2173 1.838164419 MTMR14 myotubularin related protein 14 1.53438053E-05 6.19174052E-05 1.1634 0.6164 0.5429 0.6885 0.7321 0.4469 0.8002

asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)

GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein

transcription elongation factor A (SII) N-terminal and central domain containing 2

399687 MYO18A myosin XVIIIA 3.92694818E-05 0.000146435096 1.1632 1.3000 1.6115 1.5392 1.0105 1.1717 1.40422965 GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 2.33795571E-05 9.06987827E-05 1.1628 0.8845 1.4200 2.2155 0.7090 2.8497 1.29689380 GRHPR glyoxylate reductase/hydroxypyruvate reductase 1.81455286E-05 7.21713318E-05 1.1627 0.9829 1.7856 1.2795 0.8466 2.1534 1.275864783 RBM15 RNA binding motif protein 15 5.49345103E-05 0.000198765024 1.1626 1.4039 4.6451 2.1329 1.5225 7.5536 1.478723435 TARDBP TAR DNA binding protein 1.09130667E-05 4.54636468E-05 1.1622 2.0244 3.8592 1.7118 1.6385 5.6947 2.579056672 AKIP1 chromosome 11 open reading frame 17 0.00899137021 0.019689635237 1.1615 9.9424 5.9574 1.7691 5.1241 5.1698 2.637783480 PUS3 pseudouridylate synthase 3 0.01288921767 0.026949511997 1.1603 3.4892 2.0360 1.5509 3.8353 2.9905 2.067010743 RAI1 retinoic acid induced 1 5.77502494E-05 0.000208210844 1.1582 1.0429 1.5373 0.8234 0.7886 2.1208 1.144010039 PARP3 poly (ADP-ribose) polymerase family, member 3 0.02042469123 0.040172223691 1.1570 1.2302 2.1028 3.1380 0.9932 0.4722 2.217154675 CRLS1 cardiolipin synthase 1 1.39408957E-05 5.67323041E-05 1.1567 2.6044 4.4933 1.3340 2.0411 4.5617 1.54377074 TIAM1 T-cell lymphoma invasion and metastasis 1 8.32658213E-05 0.000291573991 1.1560 0.6575 0.9411 0.9305 0.7167 0.8830 0.98355986 RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.00086427367 0.002435910614 1.1555 0.2512 0.9837 1.0399 0.5974 1.4088 0.4073817 CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.00060834846 0.001763563877 1.1542 1.8790 2.4940 1.5954 2.1396 3.4922 2.906254441 STAG3L1 stromal antigen 3-like 1 (pseudogene) 0.00088503361 0.002488663293 1.1541 1.7599 1.4144 1.3927 1.6873 1.3885 1.527825870 SUMF2 sulfatase modifying factor 2 5.97862056E-05 0.000214872846 1.1538 1.9736 1.2089 1.9127 2.3470 2.1597 2.46725609 MAP2K7 mitogen-activated protein kinase kinase 7 1.35717157E-05 5.54398367E-05 1.1522 2.5089 3.5128 1.9270 2.1875 4.9424 2.5853116496 FAM129A family with sequence similarity 129, member A 0.02218988811 0.043142544748 1.1522 1.0203 0.7429 1.4826 0.6485 0.4179 1.236563941 NECAB3 N-terminal EF-hand calcium binding protein 3 0.00898772675 0.019684015729 1.1516 1.5218 1.0350 1.8501 1.7428 1.6549 2.554522929 SEPHS1 selenophosphate synthetase 1 1.33955872E-05 5.47815956E-05 1.1509 1.3490 1.4149 0.9334 1.2257 1.6283 1.230150488 MINK1 misshapen-like kinase 1 3.50933661E-05 0.000131776816 1.1507 0.8654 0.7399 0.9617 0.6355 0.7170 0.96197553 ZNF7 zinc finger protein 7 0.01501261894 0.030786820796 1.1506 0.7615 2.4065 1.0399 0.6996 2.2811 1.576064926 RASAL3 RAS protein activator like 3 0.00016999164 0.00055495573 1.1502 1.0684 1.4105 1.1078 0.9481 2.0732 1.243210254 STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.00294713724 0.007344529688 1.1487 2.4278 1.6974 1.9530 2.3927 2.0424 2.414255311 ZNF444 Q8N0Y2,zinc finger protein 444 3.25308139E-05 0.000122683804 1.1486 2.2610 1.6118 1.6825 1.7542 1.7749 1.695010714 POLD3 polymerase (DNA-directed), delta 3, accessory subunit 0.00108210954 0.002985400187 1.1483 2.2659 1.6311 1.6727 2.0582 1.8734 1.9583333929 SNAI3 snail family zinc finger 3 0.02161531322 0.042209576054 1.1474 1.2180 2.2667 1.5785 1.1550 2.5628 1.33753831 KLC1 kinesin light chain 1 2.24105053E-05 8.73847105E-05 1.1467 0.4934 0.6424 0.9148 0.5378 0.9536 1.358155751 TMEM184C transmembrane protein 184C 0.00087289902 0.002457188554 1.1459 2.4142 2.9261 1.5797 2.0505 3.8420 2.138155577 NAGK N-acetylglucosamine kinase 0.00201202361 0.005213968998 1.1452 1.8989 1.6432 2.1203 2.1967 1.8400 2.670657707 TLDC1 TBC/LysM-associated domain containing 1 0.01530377532 0.031299595111 1.1447 1.1861 1.9737 2.0681 0.7906 2.5511 1.879810422 UBAC1 UBA domain containing 1 6.56401574E-05 0.000234161842 1.1446 0.8360 1.7148 1.7396 0.5613 2.2282 1.58553416 IDE insulin-degrading enzyme 2.62716587E-05 0.000100890237 1.1439 1.2645 1.3458 1.0201 1.1469 1.6618 1.259656886 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 6.71975551E-05 0.000239390471 1.1436 2.3238 3.0910 1.6362 1.8041 4.7161 2.527251335 NGRN neugrin, neurite outgrowth associated 0.00253987891 0.006432247744 1.1434 7.7823 3.2176 1.7387 16.2203 0.8257 1.113379719 AAGAB hypothetical protein FLJ11506 2.86118433E-05 0.000109120351 1.1418 0.4630 0.5405 1.4076 0.3724 0.2163 0.8323

1933 EEF1B2 8.62063113E-05 0.00030071816 1.1398 1.4902 2.7266 2.1470 1.8322 4.8658 3.4130

6548 SLC9A1 0.00328388155 0.008082311914 1.1396 1.0048 1.4936 1.0304 0.8474 1.4058 0.719251755 CDK12 cyclin-dependent kinase 12 7.14126029E-05 0.000253025224 1.1387 2.5310 2.4301 1.6418 2.8727 2.5210 2.2393201163 FLCN folliculin 0.00042163121 0.001265239868 1.1383 0.3321 0.3321 0.3321 0.3970 0.3970 0.397055257 MRGBP MRG/MORF4L binding protein 2.67774724E-05 0.000102724748 1.1382 2.1668 1.2929 1.5617 1.9221 0.9419 2.13579677 PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 0.00986399654 0.021380183255 1.1379 0.3798 0.8922 0.5981 0.4760 0.8545 0.478284926 SPRYD3 SPRY domain containing 3 0.0109362833 0.023349821038 1.1358 2.0135 1.9947 2.0314 1.4320 2.3881 2.12471175 AP2S1 adaptor-related protein complex 2, sigma 1 subunit 6.2955806E-05 0.000225464003 1.1357 1.3091 1.0293 1.5189 1.2044 2.2591 1.63717260 TSSC1 tumor suppressing subtransferable candidate 1 2.31429474E-05 8.99336313E-05 1.1347 1.1206 0.9286 0.9720 1.2961 0.9719 1.193551096 UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.81248305E-05 0.000107487325 1.1341 5.9991 3.6105 1.8695 5.0219 6.0759 3.1648

54921 CHTF8 8.43536179E-05 0.000294987427 1.1337 1.0861 3.1545 1.7818 0.7894 1.2196 1.329291647 ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 0.0036285141 0.008836493364 1.1324 4.8698 3.9730 1.4073 2.5475 5.1127 1.359681858 SHARPIN SHANK-associated RH domain interactor 2.32553437E-05 9.03075679E-05 1.1319 27.9006 1.8253 4.2618 7.5996 4.5353 3.645156850 GRIPAP1 GRIP1 associated protein 1 2.24296478E-05 8.74406921E-05 1.1318 1.2906 1.1460 1.2288 1.6841 1.3308 1.5436374882 TMEM205 transmembrane protein 205 9.61190334E-05 0.000331374901 1.1315 1.4866 4.9882 1.8627 0.9877 3.3259 0.387055795 PCID2 PCI domain containing 2 1.93884316E-05 7.65317393E-05 1.1313 2.4325 1.5694 2.6722 0.7248 0.7269 1.23087249 TSC2 tuberous sclerosis 2 2.65728255E-05 0.000102003922 1.1312 0.6077 0.4373 1.5874 0.5833 2.0064 0.6930133957 CCDC127 coiled-coil domain containing 127 0.00367153661 0.008932931674 1.1310 7.4967 0.4545 1.0986 2.3024 0.2563 1.79969031 BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.00016355725 0.000535288918 1.1309 0.9738 2.6930 1.2691 1.0541 3.1684 2.09304733 DRG1 developmentally regulated GTP binding protein 1 5.58169406E-05 0.000201758089 1.1304 1.9678 2.1400 1.9009 1.7590 2.4457 2.424522859 LPHN1 latrophilin 1 0.00056987673 0.001662587824 1.1299 1.5978 3.0289 1.3972 1.6982 2.4822 2.28093932 LCK lymphocyte-specific protein tyrosine kinase 0.00013185775 0.000440941593 1.1298 2.6212 2.3545 2.7800 1.9871 2.8001 1.993384895 FAM73B family with sequence similarity 73, member B 0.00020813778 0.000667326448 1.1295 1.2660 1.6027 1.5319 0.9226 1.6419 1.2557112770 C1orf85 chromosome 1 open reading frame 85 0.00299216701 0.007449635597 1.1294 1.5410 1.2822 1.2699 1.6336 1.2686 1.3729221937 FOXK1 forkhead box K1 0.00015454937 0.000508907216 1.1290 1.7279 1.7144 1.4095 1.1574 2.4000 1.416263939 FAM217B family with sequence similarity 217, member B 0.00224400466 0.005746664773 1.1278 0.9298 1.3003 1.2061 0.5568 1.1506 0.858623234 DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 0.00034433907 0.001055665008 1.1272 0.2882 0.7404 0.5574 0.4850 0.3155 0.49099391 CIAO1 cytosolic iron-sulfur assembly component 1 7.91408953E-05 0.000278517419 1.1265 2.2692 7.7032 6.4909 0.3363 19.2259 2.884551385 ZNF589 zinc finger protein 589 0.00919814322 0.020103884321 1.1263 1.7324 2.1141 1.3953 1.4198 4.1448 1.88909524 TECR trans-2,3-enoyl-CoA reductase 8.38582791E-05 0.000293479884 1.1260 1.9929 0.2360 0.4819 3.4802 0.9086 0.2410

23163 GGA3 2.42154799E-05 9.35840204E-05 1.1252 0.8652 2.8886 2.9596 0.8273 2.1977 1.30719807 IP6K1 inositol hexakisphosphate kinase 1 4.13666094E-05 0.000153409922 1.1250 1.4786 1.5355 2.1032 1.2507 1.5904 2.636329979 UBQLN1 ubiquilin 1 0.00013645623 0.000455236117 1.1249 1.7173 1.2357 1.4367 2.3002 2.1381 2.594551126 NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 5.16874714E-05 0.000187984371 1.1247 2.8473 2.4189 1.7737 2.1616 3.3573 1.81644946 OAZ1 ornithine decarboxylase antizyme 1 1.70593361E-05 6.82224094E-05 1.1223 0.3321 0.3321 0.3321 0.3970 0.3970 0.397051566 ARMCX3 armadillo repeat containing, X-linked 3 0.00073514859 0.002097538267 1.1217 3.2392 3.0293 1.7520 3.0147 3.7091 2.413384131 CEP78 centrosomal protein 78kDa 0.00639803061 0.014607624065 1.1208 0.9515 1.0181 0.9701 1.0268 1.3612 1.214284759 PCGF1 polycomb group ring finger 1 0.0014880848 0.003980425334 1.1200 1.5218 1.2039 2.0177 1.5332 1.5291 2.394451703 ACSL5 acyl-CoA synthetase long-chain family member 5 5.28300581E-05 0.000191872555 1.1199 0.6802 0.7201 0.8487 0.7138 0.8042 0.78607775 ZNF232 zinc finger protein 232 0.00688233835 0.01556555097 1.1189 1.3015 1.7271 1.0627 1.0159 1.5162 1.554564763 ZNF574 zinc finger protein 574 4.70401622E-05 0.000172490035 1.1187 1.0506 1.8324 1.2565 0.8493 1.6807 1.57993659 IRF1 interferon regulatory factor 1 0.00409343764 0.009853154073 1.1180 1.7184 2.1941 2.9274 1.2495 2.3301 2.661610204 NUTF2 nuclear transport factor 2 0.00018951882 0.000612225994 1.1180 2.6158 1.1763 3.2090 1.9673 1.4862 2.898651114 ZDHHC9 zinc finger, DHHC-type containing 9 0.01157111885 0.024550334839 1.1179 1.5354 1.1453 1.1836 1.2994 0.7823 1.746856834 GPR137 G protein-coupled receptor 137 0.00037634303 0.001142661975 1.1178 0.9835 1.3282 1.5984 0.5462 0.9246 1.171126528 DAZAP1 DAZ associated protein 1 0.00017962374 0.000583067156 1.1177 0.8985 2.2177 1.5994 1.1652 2.4903 2.808325988 HINFP histone H4 transcription factor 0.00341708209 0.008376297823 1.1177 1.0059 1.4291 1.3465 0.8588 1.8562 1.322792667 MGME1 mitochondrial genome maintenance exonuclease 1 0.00419241107 0.010071487654 1.1170 2.8292 5.0093 1.9665 1.6752 5.8186 2.181851016 EMC9 ER membrane protein complex subunit 9 0.01003155323 0.021694465699 1.1165 1.7862 3.8778 2.0388 1.5897 4.2470 2.581311102 RPP14 ribonuclease P/MRP 14kDa subunit 0.00284306532 0.007106496524 1.1162 3.3313 2.6622 1.4275 3.9012 3.9121 2.1242114049 WBSCR22 Williams Beuren syndrome chromosome region 22 3.67630933E-05 0.000137678877 1.1161 3.1233 0.4755 0.9001 0.3570 0.7512 0.966926354 GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 0.00365462831 0.008895346811 1.1158 7.4281 1.3982 4.2367 11.2995 0.9267 2.162623598 PATZ1 POZ (BTB) and AT hook containing zinc finger 1 9.03654139E-05 0.000313371957 1.1155 3.3924 6.1641 2.5000 2.7109 9.1988 3.9989

114789 SLC25A25 0.00013038945 0.000436750874 1.1143 1.3642 2.4388 1.6012 1.1574 2.3956 1.69885019 OXCT1 3-oxoacid CoA transferase 1 0.00092744894 0.002596345489 1.1135 0.6810 1.0038 1.2435 0.7404 1.5365 1.47118439 NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.59134261E-05 9.96821308E-05 1.1127 3.1038 3.4249 2.2178 2.5414 3.2206 2.32117090 TLE3 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) 0.00025019693 0.000790797158 1.1124 1.0852 1.3411 1.1829 0.8529 1.3418 1.189411253 MAN1B1 mannosidase, alpha, class 1B, member 1 0.00013268695 0.000443389901 1.1117 0.4211 1.0057 1.3051 0.6239 0.5368 0.6679637 BID BH3 interacting domain death agonist 0.00547289651 0.012720365465 1.1104 1.2838 2.3734 1.7629 0.7882 1.6359 1.1591

8813 DPM1 0.00066620579 0.001913378209 1.1102 4.5549 4.1056 3.5091 3.3603 4.2733 2.81999693 RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.01165102695 0.024702664697 1.1101 0.1175 0.0495 0.3605 0.1790 0.0202 0.2945439921 MXRA7 matrix-remodelling associated 7 0.00614675259 0.01408849264 1.1101 0.4230 0.3372 0.6340 0.3375 0.1720 0.433554955 C1orf109 chromosome 1 open reading frame 109 0.00153191689 0.00408630445 1.1100 1.4061 1.4194 1.1980 1.0355 1.9247 1.17344121 MAN1A1 mannosidase, alpha, class 1A, member 1 0.00030060084 0.000934588824 1.1097 2.1735 1.6321 1.7509 2.1750 2.4310 3.767979753 SNIP1 Smad nuclear interacting protein 1 0.00157585548 0.004190051131 1.1081 1.6859 2.3666 1.2098 1.3983 3.1242 1.694024140 FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 8.33173412E-05 0.000291698498 1.1079 5.3103 3.9356 2.2387 3.7085 4.0933 2.69263628 INPP1 inositol polyphosphate-1-phosphatase 0.02175650652 0.042439936713 1.1072 1.0948 1.2268 1.3871 0.6336 0.8397 1.291026147 PHF19 PHD finger protein 19 0.00180143025 0.004713695188 1.1069 1.9763 2.0300 1.8743 1.6715 1.8287 2.01154343 MOV10 Mov10, Moloney leukemia virus 10, homolog (mouse) 0.00860803963 0.018950132544 1.1062 1.6820 2.1154 1.7999 1.5808 1.9675 1.679257680 CHD8 chromodomain helicase DNA binding protein 8 0.00017095989 0.000557606952 1.1059 0.8065 0.8128 0.8271 0.6714 0.8624 0.78575236 PGM1 phosphoglucomutase 1 3.35454391E-05 0.000126275703 1.1058 0.9724 0.9264 0.8885 0.9640 1.2638 1.362610188 TNK2 tyrosine kinase, non-receptor, 2 0.00031432064 0.000972775526 1.1057 0.6346 0.8627 0.7492 0.5289 0.8380 0.827855486 PARL presenilin associated, rhomboid-like 3.04969202E-05 0.000115686972 1.1043 2.1793 1.8881 1.8070 2.1263 2.4551 2.136281853 TMEM14B transmembrane protein 14B 0.00026453266 0.000832507877 1.1042 0.3321 0.3321 0.3321 0.3970 0.3970 0.39708408 ULK1 unc-51 like autophagy activating kinase 1 0.00274972423 0.00689582227 1.1038 1.2260 3.4187 1.5227 0.9183 3.6899 1.06165229 PGGT1B protein geranylgeranyltransferase type I, beta subunit 0.00514147392 0.012058145478 1.1027 1.6949 2.1389 1.6519 1.8711 2.7858 1.95812926 GRSF1 G-rich RNA sequence binding factor 1 0.00022360525 0.000711673075 1.1019 1.5978 1.8749 1.8873 1.3381 3.3873 2.662364222 TOR3A torsin family 3, member A 4.25008926E-05 0.000157106273 1.1009 2.2251 2.4589 1.8983 1.4792 2.1241 2.4655

3516 RBPJ 0.00181743941 0.004751502765 1.1005 2.1766 2.1066 2.2571 2.1125 3.7223 3.87806400 SEL1L sel-1 suppressor of lin-12-like (C. elegans) 5.69729152E-05 0.000205529932 1.0992 1.8293 1.6689 1.4020 1.5479 2.0302 1.654123211 ZC3H4 zinc finger CCCH-type containing 4 0.00102671163 0.002845021971 1.0983 1.5723 2.2366 1.8628 1.7775 3.0976 2.956457590 WDFY1 WD repeat and FYVE domain containing 1 0.00196895914 0.005111069957 1.0964 2.0893 2.8359 1.4917 1.5835 3.9491 1.79335310 PKD1 polycystic kidney disease 1 (autosomal dominant) 0.00014369043 0.000477192209 1.0959 0.3265 4.6247 0.8121 0.7980 6.4043 0.899054977 SLC25A38 solute carrier family 25, member 38 4.68496706E-05 0.00017182601 1.0959 1.3492 1.4780 1.3958 1.4105 2.3948 2.611329914 UBIAD1 UbiA prenyltransferase domain containing 1 3.20732761E-05 0.000121058232 1.0955 2.4960 3.4632 1.4751 1.7481 5.0545 2.09373267 AGFG1 ArfGAP with FG repeats 1 0.00021466799 0.000685976476 1.0954 1.6770 2.4941 1.1431 0.8896 5.4469 1.918253371 NUP54 nucleoporin 54kDa 9.55921979E-05 0.00032974526 1.0954 3.2353 2.1480 2.0072 2.8858 2.9995 2.4180121457 IKBIP IKBKB interacting protein 0.00053659042 0.001574527089 1.0952 3.5689 1.8603 3.1490 3.0719 2.6268 4.428054865 GPATCH4 G patch domain containing 4 0.00379334784 0.009197459089 1.0946 2.9964 3.2609 2.6486 2.6436 4.2137 2.555064718 UNKL unkempt homolog (Drosophila)-like 0.00182884335 0.004779136912 1.0943 1.0161 1.1991 1.5456 0.7385 0.8872 1.860980279 CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.00219751829 0.005641851082 1.0939 1.9723 2.5858 1.8532 1.4586 2.8213 1.903524148 PRPF6 pre-mRNA processing factor 6 0.00029311072 0.000912232863 1.0928 2.3537 3.6476 1.8802 1.6717 4.3822 2.32705096 PCCB propionyl CoA carboxylase, beta polypeptide 3.69981942E-05 0.000138530944 1.0917 0.6581 0.9780 1.0725 0.7297 1.2096 0.929125879 DCAF13 DDB1 and CUL4 associated factor 13 0.00012100958 0.00040855267 1.0897 2.9334 2.8966 1.3292 1.3565 2.8013 0.8059

64708 COPS7B 6.33364491E-05 0.000226607323 1.0878 1.0754 1.2128 1.4375 0.8218 1.1105 0.953550626 CYHR1 cysteine/histidine-rich 1 0.00166405864 0.004397061396 1.0872 1.4765 1.5825 2.4116 1.3433 1.5751 2.0899533 ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.00030812696 0.000954853754 1.0871 2.0826 2.1742 2.1634 2.3373 2.4779 2.485564432 MRPS25 mitochondrial ribosomal protein S25 0.00027513304 0.000861860255 1.0868 1.9476 1.0736 1.6337 1.3964 1.6799 2.092158525 WIZ widely interspaced zinc finger motifs 0.00026490568 0.00083353824 1.0865 0.8440 1.6976 1.2730 0.8630 1.8116 1.021254925 ZSCAN32 zinc finger and SCAN domain containing 32 0.00406941505 0.009800494498 1.0844 1.4389 4.7493 0.6380 0.6313 3.7415 0.48976812 STXBP1 syntaxin binding protein 1 0.01856459533 0.037013943978 1.0835 1.2173 1.8423 1.9712 0.7873 1.0767 2.4576

eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1

CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)

golgi-associated, gamma adaptin ear containing, ARF binding protein 3

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit

recombination signal binding protein for immunoglobulin kappa J region

COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)

1660 DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.00043961076 0.001313584266 1.0825 0.7113 0.5148 0.7294 0.8968 0.7059 1.037479073 TMEM109 transmembrane protein 109 0.00040061269 0.001210516805 1.0822 2.3204 5.3129 2.2137 2.3398 4.7135 2.192056181 MTFR1L mitochondrial fission regulator 1-like 0.00042255403 0.001267537893 1.0821 0.9833 0.7586 1.0914 0.7332 0.6861 1.094257587 KIAA1430 KIAA1430 0.0002404447 0.000761950324 1.0812 2.4745 3.6308 2.0178 2.0579 3.6888 2.151984262 PSMG3 proteasome (prosome, macropain) assembly chaperone 3 6.23078607E-05 0.000223276962 1.0811 0.3162 7.5539 0.4552 0.5899 2.3669 0.392957380 MRS2 MRS2 magnesium transporter 9.97922351E-05 0.000342938446 1.0797 1.6683 1.6927 1.8217 1.6399 2.7140 2.2212118472 ZNF511 zinc finger protein 511 0.00734504908 0.016467329669 1.0784 3.9909 2.7502 2.5685 2.5349 3.9732 3.668551068 NMD3 NMD3 ribosome export adaptor 0.00025968301 0.000818655618 1.0783 1.1913 0.7922 0.8956 1.0959 0.9991 0.818010959 TMED2 transmembrane emp24 domain trafficking protein 2 0.00045310136 0.001349261426 1.0780 1.8982 1.8435 1.5783 2.5770 4.0355 2.59596231 RPS26 ribosomal protein S26 0.01453746943 0.029929860156 1.0777 2.7592 1.2802 1.8661 2.3847 1.8814 2.17929797 TATDN2 TatD DNase domain containing 2 0.00034348542 0.001053401395 1.0772 2.1139 2.7776 1.8866 1.5849 2.9917 1.9156164 AP1G1 adaptor-related protein complex 1, gamma 1 subunit 8.31786901E-05 0.000291324713 1.0768 0.9211 1.4431 0.8105 0.8177 1.6021 1.209555699 IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00012874104 0.000432100713 1.0766 1.6574 1.5674 1.3379 1.6037 1.5342 1.849393 ACVR2B activin A receptor, type IIB 0.00106643932 0.002945281027 1.0754 1.4206 1.0363 1.4276 0.9206 0.4932 1.071355100 WDR70 WD repeat domain 70 0.00230195044 0.00588351356 1.0752 3.0575 1.8666 1.5966 4.3959 2.4764 2.23942686 GGT7 gamma-glutamyltransferase 7 0.02566687802 0.048918868797 1.0734 0.9408 1.1928 1.3318 0.7404 0.5213 0.870422934 RPIA ribose 5-phosphate isomerase A 0.00177489751 0.004652930744 1.0727 2.4173 4.0834 1.3007 3.0265 4.3974 2.1141572 BAD BCL2-associated agonist of cell death 6.78418549E-05 0.000241356381 1.0727 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

4734 NEDD4 0.01196416286 0.025249385968 1.0712 1.0112 1.5629 1.0199 0.9596 1.6115 1.094880155 NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.00118127128 0.003233586351 1.0697 0.3321 0.3321 0.3321 0.3970 0.3970 0.397026056 RAB11FIP5 RAB11 family interacting protein 5 (class I) 0.00154424195 0.004114975771 1.0695 0.4447 0.6479 0.7280 0.3915 0.4531 0.9405401505 TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast) 0.00040830531 0.001231317811 1.0694 2.3673 1.1642 1.6404 2.1491 2.1285 2.213257062 DDX24 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 0.00053979298 0.001583161678 1.0685 3.2019 8.3260 4.2026 3.5107 10.2616 3.782410484 SEC23A Sec23 homolog A (S. cerevisiae) 6.31094068E-05 0.000225883463 1.0684 1.3170 1.6786 1.3107 1.2368 2.4112 1.540660625 DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 0.00715381757 0.016085965375 1.0682 2.1862 2.2466 2.3172 1.7048 2.4003 2.93272188 FANCF Fanconi anemia, complementation group F 0.00032624552 0.001006442364 1.0676 1.3476 2.0421 1.6751 1.6374 2.5798 2.614179183 TTPAL tocopherol (alpha) transfer protein-like 0.00042437856 0.001272230532 1.0671 0.8735 0.8196 0.7471 0.7674 0.7119 0.751484864 MINA MYC induced nuclear antigen 0.00059685675 0.001733238095 1.0662 1.6526 1.0843 1.6075 1.5281 1.2685 1.26885330 PLCB2 phospholipase C, beta 2 0.00200245656 0.00519064921 1.0628 0.9828 1.8054 1.1246 1.0525 2.6034 1.42102992 GYG1 glycogenin 1 0.00164108472 0.004345152864 1.0627 1.9442 1.8660 1.7022 1.3587 1.7934 1.8455128637 TBC1D20 TBC1 domain family, member 20 7.92369765E-05 0.000278748178 1.0622 1.7512 2.4937 1.4890 1.3905 1.8091 1.84691982 EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.00014494166 0.000480735879 1.0616 2.1347 2.2135 1.5384 1.7213 2.8952 2.35898336 HIST1H2AM histone cluster 1, H2am 0.00703953582 0.015871964268 1.0615 0.7068 7.0832 1.5225 0.3940 11.0460 2.484455716 LMBR1L limb development membrane protein 1-like 0.00029164175 0.000908125082 1.0613 1.0490 1.2444 1.1276 1.0212 1.2370 1.19247171 TPM4 tropomyosin 4 0.00029295273 0.000911896469 1.0609 0.7461 1.5798 1.3204 0.6107 1.1155 1.30985573 PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.00034903344 0.001067906733 1.0605 1.5777 2.0542 1.4250 1.5328 2.2409 1.53919657 IQCB1 IQ motif containing B1 0.00419901282 0.010082044981 1.0594 1.6717 1.6227 1.3660 0.9264 2.0838 0.956652 ACP1 acid phosphatase 1, soluble 0.00012571239 0.000423023336 1.0574 2.7318 1.7351 7.4259 0.3004 0.6914 2.492129946 SERTAD3 SERTA domain containing 3 0.01024201572 0.022081665052 1.0572 1.8525 1.8006 1.6426 2.0089 2.1229 2.370410723 SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 0.01084189757 0.023183516967 1.0571 1.5758 1.5011 1.2200 1.7840 1.0484 1.766490780 PYGO2 pygopus homolog 2 (Drosophila) 0.00011494357 0.000389764344 1.0565 1.9199 2.2895 2.6848 1.4195 3.1528 3.393110291 SF3A1 splicing factor 3a, subunit 1, 120kDa 0.0005110447 0.001506098189 1.0562 0.4587 1.4808 0.8366 0.0236 0.7552 0.23715989 RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.01392363825 0.028825370272 1.0559 1.1193 1.5742 1.7470 1.3199 1.7305 2.346954700 RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 6.47517257E-05 0.000231263396 1.0557 1.6548 0.8985 1.1730 1.7383 1.4659 1.373230827 CXXC1 CXXC finger protein 1 0.00014486757 0.000480664665 1.0537 1.9706 1.1235 1.6437 2.4203 2.2572 1.9642

9641 IKBKE 0.01038856577 0.022352787766 1.0536 2.1550 1.7216 1.7778 1.7894 1.6657 1.679155929 DMAP1 DNA methyltransferase 1 associated protein 1 0.00011312901 0.000384289521 1.0523 2.7869 1.6536 1.8671 2.6264 2.1201 1.770022800 RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.01580930108 0.032171461104 1.0512 0.8548 1.5973 0.8736 0.7001 1.1976 0.918357154 SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.00090599269 0.002542902977 1.0495 1.6041 1.3346 1.6643 1.6759 1.0075 1.7838727957 MROH1 maestro heat-like repeat family member 1 0.00033147336 0.001020330388 1.0481 0.3990 0.8276 0.6954 0.3552 1.1037 0.6999116447 TOP1MT topoisomerase (DNA) I, mitochondrial 0.00134420567 0.003631864396 1.0479 0.4352 0.8095 0.9333 0.3211 0.7228 0.637059342 SCPEP1 serine carboxypeptidase 1 0.0128878342 0.026949511997 1.0472 2.3281 1.7527 2.1764 1.7112 1.4958 1.73021453 CSNK1D casein kinase 1, delta 0.00041940527 0.001260008742 1.0458 0.3673 0.7749 0.5532 0.4764 1.0040 0.665626121 PRPF31 pre-mRNA processing factor 31 8.52996018E-05 0.000297953417 1.0446 1.5403 4.4405 1.3223 0.8643 3.1348 2.377751320 MEX3C mex-3 RNA binding family member C 0.00121490439 0.003316708945 1.0445 1.2147 1.5407 1.5495 1.6529 2.0112 2.3220157285 SGK223 homolog of rat pragma of Rnd2 0.00463289625 0.010999516673 1.0441 0.2420 0.1963 0.6416 0.3084 0.3037 0.32422014 EMP3 epithelial membrane protein 3 0.00071068694 0.002031868536 1.0436 2.1278 3.6079 1.6665 1.9131 5.4549 1.938022936 ELL2 elongation factor, RNA polymerase II, 2 0.01011562452 0.021847835837 1.0423 1.3660 2.2822 1.1873 1.5109 3.7082 1.945923474 ETHE1 ethylmalonic encephalopathy 1 0.00017539732 0.00057056433 1.0411 2.1000 2.1607 2.3080 1.5884 3.2552 2.943955677 IWS1 IWS1 homolog (S. cerevisiae) 9.10284811E-05 0.000315372091 1.0399 2.9773 3.6895 1.9830 3.5124 5.6913 2.670584991 RBM17 RNA binding motif protein 17 0.00019353143 0.000623999688 1.0394 0.7157 0.6510 1.1858 0.5011 0.8344 1.14084947 OAZ2 ornithine decarboxylase antizyme 2 0.00145192324 0.003892244935 1.0393 2.4182 2.9641 1.8882 2.0193 3.4710 1.888079188 TMEM43 transmembrane protein 43 0.00011845692 0.000400823121 1.0390 0.4124 2.4159 1.5978 0.2388 2.1114 1.089111056 DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 0.01064595523 0.022817934777 1.0387 2.3420 2.7317 1.7604 2.0826 3.3954 1.86405297 PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.00045297957 0.001349118623 1.0383 3.3798 6.1561 2.5533 1.6619 9.0613 1.948179174 CRELD2 cysteine-rich with EGF-like domains 2 0.01620539325 0.032878630405 1.0381 0.2563 0.1501 0.7332 0.3446 0.5585 0.553429919 C18orf8 chromosome 18 open reading frame 8 0.00797659988 0.017728664546 1.0371 1.8361 3.3674 2.1905 1.7288 2.8599 2.610979598 CEP97 leucine-rich repeats and IQ motif containing 2 0.01956892034 0.038705706049 1.0370 0.9198 0.6030 0.8183 1.0693 0.6263 1.14964729 NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.00120063873 0.003283159359 1.0365 2.7613 1.8572 1.3666 2.7120 3.2305 3.053123406 COTL1 coactosin-like F-actin binding protein 1 0.0004244631 0.001272275218 1.0364 1.9614 0.7812 2.5254 2.0432 0.9672 2.9886215 ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 0.00940672175 0.020503354382 1.0363 4.1396 2.0239 6.9710 1.5256 1.4006 4.69152120 ETV6 ets variant 6 0.00165515274 0.004377326811 1.0348 1.2343 1.3293 1.2403 1.4573 2.2215 1.6081196383 RILPL2 Rab interacting lysosomal protein-like 2 0.00045647206 0.001358413261 1.0348 1.4565 2.2041 1.5021 1.4992 3.3699 2.09992039 DMTN dematin actin binding protein 0.00982375457 0.021303067124 1.0327 0.7595 0.8536 0.7664 0.4075 0.6565 0.711155262 C7orf43 chromosome 7 open reading frame 43 0.00016285353 0.000533559201 1.0321 1.7821 1.7686 1.8336 1.1324 1.2654 2.0137

517 ATP5G2 0.0008336117 0.002354576126 1.0321 2.2965 2.2570 1.9819 2.0113 2.4061 1.986810904 BLCAP bladder cancer associated protein 0.00161317913 0.004278706496 1.0306 1.0080 1.0332 1.4332 0.9318 1.0861 1.385511261 CHP1 calcineurin-like EF-hand protein 1 0.00015996998 0.000525502172 1.0293 2.0996 1.9741 3.0257 1.1198 2.3044 1.857956683 C21orf59 chromosome 21 open reading frame 59 0.00014666595 0.000485573501 1.0278 0.6200 0.7603 0.6897 0.7610 1.1181 1.165479230 ZNF557 zinc finger protein 557 0.00771442532 0.017206784596 1.0255 1.9751 2.3562 1.4880 1.5283 3.7571 2.02677157 TP53 tumor protein p53 0.00052521131 0.001545091902 1.0243 0.2080 0.2107 0.2624 0.3757 0.2201 0.331955669 MFN1 mitofusin 1 0.00862362835 0.018977590893 1.0242 1.1368 1.0356 0.9155 1.0989 1.0889 1.097027000 DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.00157860972 0.004195542817 1.0239 1.6613 1.5620 1.2495 1.3766 1.8363 1.366123365 ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.00477118805 0.01129409873 1.0235 0.5997 1.1243 0.9764 0.6138 1.6499 0.8843729082 OIP5-AS1 OIP5 antisense RNA 1 0.00021082685 0.000674764084 1.0233 2.8312 2.8769 1.7364 2.7987 4.1047 2.777755846 ITFG2 integrin alpha FG-GAP repeat containing 2 0.00998742211 0.021604140745 1.0218 2.4351 2.0771 1.6945 2.4192 3.0198 2.657055299 BRIX1 Q8TDN6,BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) 0.00188059558 0.004900490939 1.0211 2.6491 2.2879 1.3484 1.7722 1.1945 1.4772374395 TMEM179B transmembrane protein 179B 0.00039409225 0.001192589204 1.0203 1.6861 2.2863 1.9833 1.6884 4.1822 2.85088455 ATRN attractin 0.00072492469 0.002069983434 1.0202 2.6644 3.0963 1.9661 2.0029 4.1552 2.3073118881 COMTD1 catechol-O-methyltransferase domain containing 1 0.01017369249 0.02194990072 1.0178 1.3572 1.9127 1.2052 1.0288 2.0794 1.292455367 PIDD p53-induced death domain protein 0.00468275571 0.011104907504 1.0177 0.8567 1.0996 1.3047 0.5706 1.0321 1.00652746 GLUD1 glutamate dehydrogenase 1 0.00092685697 0.002595085889 1.0172 5.0601 7.0571 2.0393 2.9674 5.3610 2.505310066 SCAMP2 secretory carrier membrane protein 2 0.00064035639 0.001845810361 1.0169 0.8792 0.9613 1.4106 1.0981 0.8912 1.370823670 TMEM2 transmembrane protein 2 0.00102032417 0.002828383556 1.0155 0.7464 0.8012 0.6048 0.8416 1.0959 1.0832317762 CCDC85C chromosome 14 open reading frame 65 0.00169187487 0.004462173436 1.0152 1.4090 2.8049 1.4052 1.4112 2.0816 2.521484549 MAK16 MAK16 homolog (S. cerevisiae) 0.00136591395 0.00368274747 1.0145 1.4972 2.2594 2.2371 1.9385 2.6958 2.64033300 DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00013938312 0.000464322406 1.0141 0.8867 1.7264 1.5498 0.7140 1.3889 1.107584681 HINT2 histidine triad nucleotide binding protein 2 0.00866239279 0.019049132387 1.0139 1.7155 2.4855 1.6778 2.1060 2.3395 2.741291012 CERS5 LAG1 homolog, ceramide synthase 5 (S. cerevisiae) 0.00021699338 0.000693043706 1.0138 0.7810 1.4339 1.2395 0.8745 2.1655 1.16991408 CRY2 cryptochrome circadian clock 2 0.00060822596 0.001763488526 1.0129 1.0031 1.3640 0.8540 1.0953 1.7078 0.92555715 PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 0.00017487132 0.000568954543 1.0125 27.2539 20.7609 5.9975 14.5075 12.0034 4.9646

10971 YWHAQ 0.00370321347 0.009004007515 1.0125 1.7054 1.1500 1.4817 1.3509 1.4046 2.523510426 TUBGCP3 tubulin, gamma complex associated protein 3 0.00017589172 0.000571968953 1.0107 1.7894 2.8230 1.6148 1.5787 4.1938 2.449854623 PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.00017457447 0.000568191085 1.0106 0.2063 2.7746 1.6314 0.1301 3.1859 1.04333301 DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00173653921 0.004566131018 1.0093 2.1124 2.6029 2.1412 1.6815 3.3424 2.31589933 KIAA0020 KIAA0020 0.00748188879 0.01674740561 1.0092 3.5973 2.0683 1.4679 3.3002 3.7276 1.67439025 RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.00238010692 0.006062918382 1.0090 2.0254 1.6079 1.2922 2.1694 2.2163 1.7085262 AMD1 adenosylmethionine decarboxylase 1 0.0010731353 0.002961088525 1.0084 2.4964 2.2275 2.0599 1.7957 2.1404 1.938655770 EXOC2 exocyst complex component 2 0.00252824169 0.006405439856 1.0079 2.8982 4.7220 1.8061 3.7723 6.5076 2.46975825 ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 0.0142568259 0.029421811935 1.0046 0.9333 1.3526 1.0727 0.9136 1.6233 1.3208221830 TWISTNB TWIST neighbor 0.00028067983 0.000877580726 1.0046 1.7017 1.7116 1.9719 1.5870 2.4344 1.85934144 MAT2A methionine adenosyltransferase II, alpha 0.00093898676 0.00262502541 1.0042 2.6949 2.8395 2.0089 1.6775 4.5901 1.729283607 AMMECR1L AMME chromosomal region gene 1-like 0.00115344866 0.003165011846 1.0040 1.4612 2.2649 1.6085 2.0163 3.0079 2.150389845 ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 0.00334271951 0.008211638989 1.0039 0.7126 0.5638 0.6598 0.7472 0.8421 0.834881932 HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 0.00436184468 0.010422338964 1.0031 1.6880 1.2231 1.4446 1.4882 1.2310 1.34418131 NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.00035830547 0.00109316374 1.0017 1.0393 2.6416 1.6543 0.6990 3.4375 1.720364374 SIL1 SIL1 nucleotide exchange factor 0.00992462162 0.021488646307 1.0013 1.2834 1.0347 1.0342 0.9048 1.1592 1.035410524 KAT5 K(lysine) acetyltransferase 5 0.00031653861 0.000978810867 1.0009 1.4252 1.8476 1.9867 1.3280 2.0461 2.38127386 UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.00095228558 0.002658542733 1.0008 1.8069 2.5183 1.8859 1.6043 2.2401 2.4266829 CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.00120521495 0.003293208855 1.0003 0.3321 0.3321 0.3321 0.3970 0.3970 0.397079868 ALG13 chromosome X open reading frame 45 0.00064118535 0.00184790832 -1.0007 1.6048 2.4586 1.8863 1.5346 3.5360 2.058310735 STAG2 stromal antigen 2 0.00083646775 0.00236118317 -1.0017 1.7689 2.2735 1.7367 2.6639 4.1417 3.11445814 PURB purine-rich element binding protein B 0.00014332264 0.000476190897 -1.0022 1.8280 2.2883 1.8446 1.6406 1.8691 2.629426003 GORASP2 golgi reassembly stacking protein 2, 55kDa 0.00113275947 0.00311525903 -1.0042 0.4941 0.5586 0.8006 0.6536 0.5484 0.732651759 C9orf78 chromosome 9 open reading frame 78 0.00082364958 0.00232895776 -1.0053 0.9160 0.5861 1.1333 0.8050 0.3397 0.698551100 SH3GLB1 SH3-domain GRB2-like endophilin B1 0.00028427557 0.000887003373 -1.0064 2.1650 1.9057 2.1855 1.9622 2.5670 3.87155635 PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 0.00045287313 0.001349021504 -1.0078 2.2593 2.0615 2.3037 1.9972 1.9476 2.35964289 MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.00027465244 0.000860649876 -1.0106 1.1992 1.7016 1.8443 1.2325 1.9116 1.74026801 STRN striatin, calmodulin binding protein 0.00011909025 0.00040251889 -1.0110 3.0089 2.4004 1.8815 2.5283 2.7845 2.218554812 AFTPH aftiphilin 0.00015547584 0.000511773484 -1.0117 1.7553 1.5050 1.1180 1.8346 1.6340 1.398879832 QSER1 glutamine and serine rich 1 0.00534703601 0.012473004205 -1.0120 0.8172 1.0590 0.6934 0.8256 1.6608 1.094751072 MEMO1 mediator of cell motility 1 0.00014762787 0.000488315803 -1.0124 0.5598 0.7020 0.7307 0.5123 0.7885 0.813955578 SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.00012714931 0.000427465 -1.0126 1.0232 1.3851 0.6166 0.9103 1.3776 0.7637159013 CXorf38 chromosome X open reading frame 38 0.00015074124 0.000497533213 -1.0133 2.7275 2.2125 1.5363 1.9025 2.8149 1.5922132720 C4orf32 chromosome 4 open reading frame 32 0.01262899845 0.026481186552 -1.0154 1.3641 1.4005 1.3523 1.9564 2.9631 1.36839640 ZNF592 zinc finger protein 592 0.00025270004 0.000798065692 -1.0162 1.1818 1.5036 1.2279 1.1420 2.2756 1.82635757 PTMA prothymosin, alpha 9.16229473E-06 3.88250114E-05 -1.0166 1.1250 2.2790 1.7308 2.0933 6.5943 3.049655125 CEP192 centrosomal protein 192kDa 0.00013372692 0.000446696149 -1.0189 0.4272 0.7405 0.5716 0.5016 1.0745 0.762178991 PCYOX1L prenylcysteine oxidase 1 like 0.0022422004 0.005743654246 -1.0195 1.1040 0.6455 1.1767 0.7537 0.6212 0.9883338692 ANKRD13D ankyrin repeat domain 13 family, member D 0.00169870477 0.004476955661 -1.0210 0.6010 1.1123 1.1505 0.5537 1.5427 1.2743

neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

66008 TRAK2 trafficking protein, kinesin binding 2 0.00012760462 0.000428727256 -1.0217 6.2481 2.0940 4.7118 1.6813 0.8029 2.558079621 RNASEH2B ribonuclease H2, subunit B 0.00897636275 0.019666199051 -1.0234 2.1351 0.7490 1.5712 1.1215 0.5848 1.484725936 NSL1 NSL1, MIS12 kinetochore complex component 0.00010465184 0.000358290873 -1.0242 0.4147 1.2833 1.7293 0.5442 4.3391 2.136654439 RBM27 RNA binding motif protein 27 0.00017824879 0.000579088386 -1.0249 2.1457 3.4938 2.0370 2.0322 4.7456 2.556410776 ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00088595069 0.002490858741 -1.0250 1.1018 0.9102 1.1168 1.1045 1.1938 1.61445516 PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 9.96667519E-05 0.000342603429 -1.0254 1.4172 1.0811 1.0112 1.1375 1.6086 1.08135257 PHKB phosphorylase kinase, beta 0.00082117478 0.002322319396 -1.0258 0.1165 0.5986 1.1053 0.2859 0.6409 0.486655855 FAM45B family with sequence similarity 45, member A pseudogene 0.00013898325 0.000463090006 -1.0269 0.3654 1.1020 0.7140 0.3215 1.3419 0.9511375748 ERCC6L2 RAD26L hypothetical protein 0.00169752053 0.004474479961 -1.0292 0.9229 1.5315 1.6817 0.6611 0.8155 1.075557134 MAN1C1 mannosidase, alpha, class 1C, member 1 0.01851858603 0.036940131429 -1.0297 1.6468 5.5951 1.8072 1.8811 5.6221 2.817722861 NLRP1 NLR family, pyrin domain containing 1 0.00063739367 0.00183814032 -1.0307 1.7476 2.6060 1.6959 1.6888 2.0023 1.480879595 SAP130 Sin3A-associated protein, 130kDa 9.06195707E-05 0.000314074506 -1.0311 0.6476 1.2203 0.9911 0.6866 1.1600 1.016023412 COMMD3 COMM domain containing 3 0.00026786633 0.000841694499 -1.0318 0.3321 0.3321 0.3321 0.3970 0.3970 0.39709958 USP15 ubiquitin specific peptidase 15 0.00022211339 0.000707294497 -1.0319 14.2027 2.3752 0.5845 12.8711 2.4726 1.62738766 RAB11A RAB11A, member RAS oncogene family 0.00059060718 0.001716763341 -1.0321 1.5586 2.5411 1.4625 2.4276 4.9261 2.46115430 POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.00136955507 0.003691475182 -1.0351 7.8693 25.4227 1.7027 12.2396 21.2413 1.569923161 SNX13 sorting nexin 13 0.00094230729 0.002633502417 -1.0355 1.3153 0.9703 1.1828 1.3287 1.5523 1.3290286205 SCAI chromosome 9 open reading frame 126 0.0242626616 0.046685694261 -1.0355 1.3928 2.9164 1.2327 1.2530 1.8768 1.09447411 VBP1 von Hippel-Lindau binding protein 1 9.03552423E-05 0.000313371957 -1.0362 1.3656 3.0739 1.8436 1.4880 2.8640 2.612784809 CROCCP2 hypothetical protein MGC12760 0.00456942097 0.010866156394 -1.0366 0.6212 0.7680 0.9451 0.6715 0.9877 0.974510428 CFDP1 craniofacial development protein 1 0.00059886733 0.00173800887 -1.0373 1.9924 2.3505 2.0295 2.4124 3.5889 2.7705253959 RALGAPA1 GTPase activating Rap/RanGAP domain-like 1 8.2003704E-05 0.000287484973 -1.0377 0.9127 0.5168 0.4012 0.8508 0.5497 0.669251752 ERAP1 endoplasmic reticulum aminopeptidase 1 0.00050835885 0.00149914992 -1.0383 1.6593 1.1290 1.0426 1.8725 1.1568 1.205555291 PPP6R3 protein phosphatase 6, regulatory subunit 3 0.00075793788 0.002157507553 -1.0385 0.4409 0.4114 0.5701 0.6661 0.5735 0.83458284 KDM5D lysine (K)-specific demethylase 5D 0.01557044237 0.031770309661 -1.0399 1.0431 0.7320 0.8072 1.1716 0.7783 1.00761362 CPD carboxypeptidase D 9.72233761E-05 0.000334866264 -1.0403 2.4160 3.0478 2.1422 2.0154 2.7893 1.8650114803 MYSM1 Myb-like, SWIRM and MPN domains 1 0.000779908 0.002214182565 -1.0406 0.7014 1.1315 0.4939 0.6664 2.0489 0.7621161176 SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00081972238 0.002318570786 -1.0410 0.1776 0.1246 0.4759 0.1564 0.0963 0.410291782 CHMP7 CHMP family, member 7 0.00063281153 0.001827540259 -1.0434 1.7409 2.2367 1.4662 1.7570 1.7481 1.204391603 ZNF830 zinc finger protein 830 0.00093224259 0.002608566089 -1.0435 0.1357 2.8257 1.6910 0.1057 3.0463 0.9145146198 ZFP90 ZFP90 zinc finger protein 0.00109537968 0.00301745477 -1.0441 1.7480 2.0163 1.8819 1.4372 2.4413 2.007823429 RYBP RING1 and YY1 binding protein 0.00425238892 0.010195466518 -1.0446 2.3177 6.3176 1.6397 2.5497 5.8306 2.23581983 EIF5 eukaryotic translation initiation factor 5 0.00182999198 0.004780216354 -1.0450 1.4449 1.3796 1.8577 1.6991 2.0089 2.890251136 RNFT1 ring finger protein, transmembrane 1 0.00130978204 0.003549738579 -1.0451 2.9933 1.6294 1.8029 2.4015 2.2377 2.35707444 VRK2 vaccinia related kinase 2 0.00394486304 0.009525642594 -1.0469 0.6219 0.9790 0.7478 0.5767 0.9950 0.861910724 MGEA5 meningioma expressed antigen 5 (hyaluronidase) 0.00031460344 0.000973321051 -1.0478 1.3410 2.3147 0.7288 1.8863 4.0331 1.46677763 ZFAND5 zinc finger, AN1-type domain 5 0.00066445645 0.00190925432 -1.0478 1.8266 2.1273 1.4312 1.2897 1.8635 1.3754253039 PSMD5-AS1 hypothetical protein LOC253039 0.00314209307 0.007781556595 -1.0495 0.1248 6.4658 7.0841 0.0851 0.3773 0.657151426 POLK polymerase (DNA directed) kappa 0.00381945494 0.009246036127 -1.0498 0.6309 2.4057 0.7376 0.1636 0.8350 0.274155069 TMEM248 transmembrane protein 248 0.00056893379 0.001660367053 -1.0522 2.2685 2.6391 2.1716 1.8174 3.6347 3.332523479 ISCU iron-sulfur cluster assembly enzyme 0.00011417359 0.000387333787 -1.0523 2.5146 2.0524 1.6279 2.5806 3.4706 2.5562162989 DEDD2 death effector domain containing 2 0.00012981128 0.000435293029 -1.0524 0.9590 4.5643 1.7527 0.6269 16.3749 1.331755690 PACS1 phosphofurin acidic cluster sorting protein 1 0.00044265313 0.001321810417 -1.0526 1.4124 0.7344 1.0782 1.4110 1.2072 1.335310923 SUB1 SUB1 homolog (S. cerevisiae) 0.00064778818 0.001865172645 -1.0526 1.1909 1.1713 1.2978 1.6008 1.4551 1.73098036 SHOC2 soc-2 suppressor of clear homolog (C. elegans) 8.76524839E-05 0.000305122154 -1.0535 1.7277 1.1579 0.9561 1.4595 0.8742 1.22688089 YEATS4 YEATS domain containing 4 6.64438716E-05 0.000236844015 -1.0540 1.4806 1.2255 2.2215 1.3115 1.5787 2.2928916 CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.0003427806 0.001051416348 -1.0542 3.4987 2.3061 1.9749 2.9479 4.8177 2.24119595 CYTIP cytohesin 1 interacting protein 0.00053038918 0.001559084809 -1.0545 2.0186 2.2424 1.6767 2.2806 3.3796 1.810655860 ACTR10 actin-related protein 10 homolog (S. cerevisiae) 0.00011911365 0.000402523507 -1.0547 1.4734 1.1305 0.8347 1.4617 1.6256 1.01109706 ULK2 unc-51 like autophagy activating kinase 2 0.00378582417 0.009184091769 -1.0548 0.9686 0.7408 1.4800 0.9450 0.8161 2.25962971 GTF3A general transcription factor IIIA 0.00058380244 0.00169941664 -1.0554 2.5315 3.4016 2.1009 2.1770 4.4565 1.941164431 ACTR6 ARP6 actin-related protein 6 homolog (yeast) 0.00230725897 0.005896256773 -1.0558 2.7892 2.8222 2.1471 2.8559 2.8068 2.70851075 CTSC cathepsin C 0.00147007211 0.00393743149 -1.0558 2.3486 2.9133 2.4235 1.9572 2.3085 2.668957559 STAMBPL1 STAM binding protein-like 1 0.00687354942 0.015549522712 -1.0558 0.6563 1.1072 1.2655 0.6967 1.1898 0.9505839 CASP6 caspase 6, apoptosis-related cysteine peptidase 0.0019038531 0.004957560764 -1.0582 1.9501 1.5570 2.0500 1.7150 1.6107 2.415055653 BCAS4 breast carcinoma amplified sequence 4 0.00010594718 0.000362182774 -1.0584 2.0176 4.2898 2.1851 1.7355 3.1021 2.112422920 KIFAP3 kinesin-associated protein 3 0.00804281425 0.017857101537 -1.0586 1.2668 1.3835 0.9551 1.0633 1.0762 0.842755193 PBRM1 polybromo 1 0.00023471057 0.000745200957 -1.0587 0.5347 0.5350 0.5371 0.5233 0.4868 0.530857291 DANCR differentiation antagonizing non-protein coding RNA 6.90121899E-05 0.000245138167 -1.0590 0.2868 0.2641 2.1232 0.3294 0.1157 0.4709285190 RGPD4 RANBP2-like and GRIP domain containing 4 0.00035074831 0.001071897154 -1.0591 0.1458 0.1605 0.2237 0.3737 0.2362 0.25415187 PER1 period circadian clock 1 0.00020619081 0.000661316204 -1.0610 1.1964 2.0974 1.4917 0.9579 2.3926 1.335456889 TM9SF3 transmembrane 9 superfamily member 3 0.00049384824 0.001460837794 -1.0624 3.8118 1.4087 2.0451 2.7936 2.0015 2.31333107 HLA-C major histocompatibility complex, class I, C 5.66840154E-05 0.000204608915 -1.0629 0.6497 0.6988 0.5572 0.6862 0.8164 0.62032932 GSK3B glycogen synthase kinase 3 beta 5.46422537E-05 0.00019790352 -1.0635 0.6605 2.2895 0.5430 0.9711 4.9796 1.36552995 GYPC glycophorin C (Gerbich blood group) 0.00048798191 0.00144418618 -1.0636 2.2205 1.4040 1.1464 1.8627 1.4647 1.395451643 TMBIM4 transmembrane BAX inhibitor motif containing 4 0.00648516241 0.014786235031 -1.0644 0.3321 0.3321 0.3321 0.3970 0.3970 0.39709662 CEP135 centrosomal protein 135kDa 0.00396675979 0.009577250905 -1.0646 1.0088 1.1165 0.9789 0.7374 1.0901 1.1964140775 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 0.00030612657 0.000949829287 -1.0649 2.6423 0.3958 2.5412 1.7296 0.9669 1.498080254 CEP63 centrosomal protein 63kDa 0.0051173933 0.012017094246 -1.0652 1.5202 2.1993 1.0965 1.3473 1.3753 0.9072728661 SLC35E2B solute carrier family 35, member E2B 0.00041700515 0.001253416372 -1.0655 0.7672 1.2611 0.8997 0.8478 1.5113 1.104523059 CLUAP1 clusterin associated protein 1 0.00649174229 0.01479799171 -1.0656 1.2810 1.7472 1.4622 0.9983 1.5514 1.26048653 DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.02035767971 0.040061984242 -1.0662 2.9636 1.8822 1.4168 2.9707 2.4688 1.8946

6601 SMARCC2 0.00044745552 0.001333970824 -1.0665 2.1890 4.8856 2.1916 1.8808 4.9528 3.11305921 RASA1 RAS p21 protein activator (GTPase activating protein) 1 8.60045906E-05 0.000300071774 -1.0667 2.1423 2.3515 1.2138 2.0581 2.8949 2.0004254863 TMEM256 chromosome 17 open reading frame 61 0.00095134938 0.002656334953 -1.0670 0.3321 0.3321 0.3321 0.3970 0.3970 0.397055671 SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) 0.00032939826 0.001014626614 -1.0671 1.0132 1.3039 0.8730 0.9181 1.8929 1.408964417 C5orf28 chromosome 5 open reading frame 28 0.00452345441 0.010769063056 -1.0714 2.1853 2.4281 1.7893 1.9975 2.7925 2.3301728932 GPR89C G protein-coupled receptor 89C 0.00099383696 0.002762304378 -1.0722 0.1289 0.1708 0.2827 0.3913 0.0796 0.177323240 KIAA0922 KIAA0922 9.60219039E-05 0.000331102515 -1.0729 0.7115 1.1061 0.7990 0.8098 1.2637 1.03702595 GANC glucosidase, alpha; neutral C 0.01884786286 0.037494627126 -1.0730 1.8359 3.5567 2.2299 1.2769 3.5004 1.109622927 HABP4 hyaluronan binding protein 4 0.00068082886 0.001951082942 -1.0731 1.2573 1.2414 1.7563 1.1425 1.4156 2.286723585 TMEM50A transmembrane protein 50A 0.00036625137 0.00111438451 -1.0732 1.7389 2.2527 1.0861 0.6067 2.3607 1.078510163 WASF2 WAS protein family, member 2 0.0004287411 0.001283834384 -1.0737 2.4666 2.0796 2.0248 2.7052 2.6113 2.9158167227 DCP2 DCP2 decapping enzyme homolog (S. cerevisiae) 9.92555679E-05 0.000341466633 -1.0748 2.3645 2.2461 2.5220 2.6447 3.9985 2.37165955 RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00034971512 0.001069368104 -1.0749 1.6209 1.7922 1.5820 1.0474 1.8523 1.578123049 SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.00043088469 0.001289407954 -1.0754 0.5232 0.8671 0.7924 0.6472 1.3498 1.041879089 TMUB2 transmembrane and ubiquitin-like domain containing 2 8.06658291E-05 0.00028328388 -1.0759 0.6599 1.3071 1.3426 0.4962 0.9036 0.7461286336 FAM78A family with sequence similarity 78, member A 0.00041714164 0.001253620392 -1.0778 2.7803 2.3085 2.6499 2.3882 2.7151 2.985151386 EIF3L eukaryotic translation initiation factor 3, subunit L 9.39021317E-05 0.000324405322 -1.0780 2.0103 2.4517 2.0577 1.8165 5.5535 2.99964736 RPL10A ribosomal protein L10a 9.38522978E-06 3.9640989E-05 -1.0791 1.7861 1.7234 2.0063 1.2823 2.2754 2.5245330 BIRC3 baculoviral IAP repeat containing 3 0.00042709475 0.001279114117 -1.0802 2.7909 3.4053 2.2436 3.2478 4.1384 3.14655128 CDK17 cyclin-dependent kinase 17 6.85131147E-05 0.000243460061 -1.0807 2.8866 1.9419 2.0180 3.1845 2.2776 3.23605062 PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.00043807439 0.001309421755 -1.0809 2.1654 2.4982 0.9676 2.6802 3.5597 1.85741265 CNN2 calponin 2 0.00025845975 0.000814939869 -1.0816 1.3944 2.8452 1.4880 1.4936 2.7419 1.98123021 H3F3B H3 histone, family 3B (H3.3B) 0.00713281629 0.016056182328 -1.0822 0.6808 1.0867 0.7775 0.7514 1.3572 1.42017770 ZNF227 zinc finger protein 227 0.01180404381 0.024975400982 -1.0824 1.0691 0.8503 0.8070 1.5354 0.9635 1.09824820 NKTR natural killer cell triggering receptor 0.0006169248 0.00178587609 -1.0825 0.9386 1.3045 0.6866 0.7214 0.9616 0.47289126 SMC3 structural maintenance of chromosomes 3 0.00034986819 0.001069386336 -1.0830 2.4358 2.6512 1.6192 2.6593 4.1192 2.431755252 ASXL2 additional sex combs like 2 (Drosophila) 0.00026598858 0.000836657491 -1.0834 0.9593 0.8388 1.0532 0.9863 1.1782 1.24523480 IGF1R insulin-like growth factor 1 receptor 0.00029096557 0.000906328493 -1.0866 0.8008 0.7926 0.5144 1.0453 1.4619 1.077454799 MBTD1 mbt domain containing 1 0.00951683312 0.02070747326 -1.0878 1.0330 0.9822 1.8936 0.9940 0.6929 1.611155619 DOCK10 dedicator of cytokinesis 10 0.00042091384 0.001263709773 -1.0880 1.3168 1.1641 0.7040 1.2141 1.3566 0.85017378 UPP1 uridine phosphorylase 1 0.00407542589 0.009812383956 -1.0883 1.6247 2.2572 2.4501 1.5688 3.2576 2.860465018 PINK1 PTEN induced putative kinase 1 0.00629436129 0.014385312002 -1.0884 0.9678 0.4972 0.5873 0.9052 0.5663 0.685454465 ETAA1 Ewing tumor-associated antigen 1 0.00380697428 0.009221932134 -1.0886 1.7933 2.0500 1.7606 1.8518 3.6805 2.6374100506736 SLFN12L schlafen family member 12-like 0.01473816221 0.030281760925 -1.0895 2.9813 2.1152 1.6288 2.6727 1.6066 1.59353097 HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.00037725253 0.001145233123 -1.0930 1.6588 2.2410 0.9933 2.3179 3.6257 3.07554660 PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.00678116758 0.015372890079 -1.0933 0.9358 0.6575 0.6611 0.9664 0.6855 0.82843212 HOXB2 homeobox B2 0.00528332402 0.012343772305 -1.0962 0.8545 1.5050 1.5472 0.6705 0.7927 0.6170

51257 MARCH2 0.00300409731 0.007476282484 -1.0972 1.3105 0.9547 1.2408 0.5810 0.9315 0.977823635 SSBP2 single-stranded DNA binding protein 2 0.01426602178 0.029437464698 -1.0974 0.8974 1.2975 2.1984 1.3139 1.0505 2.96515586 PKN2 protein kinase N2 0.00229562056 0.005868155965 -1.0986 1.6712 2.1152 1.0667 1.7728 2.7523 1.576810476 ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 0.00013004721 0.0004357861 -1.0991 1.5049 1.0459 1.4461 0.6136 2.7734 0.403179591 C10orf76 chromosome 10 open reading frame 76 0.00012507894 0.000421046852 -1.0991 0.8743 0.7418 0.8353 0.7221 0.7836 1.04586304 SATB1 SATB homeobox 1 0.00166572969 0.004400204273 -1.1000 3.3267 2.9862 1.6377 2.8495 3.3476 2.11987326 UBE2G1 ubiquitin-conjugating enzyme E2G 1 6.41005625E-05 0.000229116878 -1.1030 1.6705 1.0446 1.6187 1.7023 1.6131 2.059351635 DHRS7 dehydrogenase/reductase (SDR family) member 7 6.02166052E-05 0.00021629208 -1.1040 0.9713 0.9043 1.1501 0.9638 0.8796 1.221427163 NAAA N-acylethanolamine acid amidase 0.00013669219 0.000455940055 -1.1041 0.9726 1.7514 1.3421 1.0534 2.3624 2.039885363 TRIM5 tripartite motif containing 5 0.01101306314 0.023500022161 -1.1044 1.0936 1.3661 0.7501 1.0533 1.4779 0.702779745 CLIP4 CAP-GLY domain containing linker protein family, member 4 0.00142793453 0.003832998341 -1.1056 0.4908 0.4256 0.6317 0.5894 0.4042 0.45585007 OSBP oxysterol binding protein 4.15297322E-05 0.000153889934 -1.1072 0.6329 0.6074 0.8549 0.6995 0.9606 1.14859994 CASP8AP2 caspase 8 associated protein 2 0.00015357609 0.000505975905 -1.1077 2.3208 3.5145 2.5834 2.2136 5.2727 3.6703441108 C5orf56 hypothetical gene supported by AK128882 0.02093755577 0.041079246102 -1.1081 3.4433 3.7411 2.5381 2.7356 3.8261 2.766123398 PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 6.04563779E-05 0.00021711064 -1.1090 2.0327 0.5348 0.2078 1.5651 0.4118 1.04229702 CEP57 centrosomal protein 57kDa 0.00017164509 0.000559254486 -1.1098 3.0207 2.0220 1.9133 2.9827 2.2848 3.31315311 PKD2 polycystic kidney disease 2 (autosomal dominant) 0.00830070026 0.018350925012 -1.1099 0.4383 0.6287 0.4288 0.5124 0.4692 0.63926188 RPS3 ribosomal protein S3 1.51619598E-05 6.12638535E-05 -1.1101 0.2099 0.1829 0.4661 0.0912 0.0378 0.2626274 BIN1 bridging integrator 1 0.0003695077 0.001123401785 -1.1106 1.1885 2.2497 2.1338 0.9707 1.8781 1.930026228 STAP1 signal transducing adaptor family member 1 0.01662864352 0.033610461767 -1.1111 4.0662 1.6686 1.2137 2.5340 0.6895 0.873251430 SUCO SUN domain containing ossification factor 0.00108997726 0.003004837747 -1.1113 2.3091 3.1697 1.1465 2.7660 5.1538 2.570151506 UFC1 ubiquitin-fold modifier conjugating enzyme 1 0.00016107209 0.000528291007 -1.1119 1.9955 2.8864 1.9803 2.7793 6.0599 2.327556829 ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.00032822398 0.001011691728 -1.1121 1.5281 1.3446 1.5289 1.3751 1.4824 2.26657544 ZFY zinc finger protein, Y-linked 0.00271443993 0.006823255796 -1.1127 1.1760 1.9751 0.8737 1.1517 1.8821 1.87299367 RAB9A RAB9A, member RAS oncogene family 0.00026883727 0.000844454975 -1.1137 2.8396 3.3846 2.0138 2.7466 4.2959 2.11556192 RPS4Y1 ribosomal protein S4, Y-linked 1 0.0219004611 0.042674384842 -1.1145 1.6889 0.4907 0.5437 1.1947 0.8080 0.5811100506779 BZRAP1-AS1 BZRAP1 antisense RNA 1 0.00077917947 0.002212458004 -1.1146 2.1330 2.3808 2.1813 1.7099 5.8404 1.961664062 RBM26 RNA binding motif protein 26 2.30491046E-05 8.96261417E-05 -1.1155 1.1180 0.9144 0.6621 1.1311 1.5272 0.59805908 RAP1B RAP1B, member of RAS oncogene family 0.00030166962 0.000937592655 -1.1164 2.6703 4.0896 1.6285 2.6884 3.2655 2.307255139 ANKZF1 ankyrin repeat and zinc finger domain containing 1 0.00425852383 0.010206157841 -1.1185 0.8934 1.8877 1.4569 0.5550 0.9783 1.12998495 PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.01412287766 0.029191540795 -1.1186 0.6471 0.6666 0.7688 0.4935 0.6732 0.68757976 FZD3 frizzled class receptor 3 0.02116017599 0.041462598995 -1.1189 1.6603 4.0739 2.7074 1.1005 3.2183 2.3985140739 UBE2F ubiquitin-conjugating enzyme E2F (putative) 0.00156554047 0.004165655367 -1.1198 2.3842 2.6508 2.6227 1.6691 1.4031 1.7463

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase

2310 FOXO3B forkhead box O3B pseudogene 5.87383619E-05 0.000211397941 -1.1203 0.0841 0.0428 0.2132 0.2852 0.3918 0.529855180 LINS lines homolog (Drosophila) 0.00031798066 0.000982937348 -1.1220 2.3711 0.7569 1.5390 2.1252 1.0251 1.84809674 KIAA0040 KIAA0040 0.00020067 0.000645081309 -1.1226 2.1125 3.2883 1.5890 2.3551 3.9406 1.97199459 ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.0001600397 0.000525565317 -1.1243 1.9171 3.0764 2.0879 1.9463 2.7303 1.7549205428 C3orf58 chromosome 3 open reading frame 58 0.00012866095 0.000431911239 -1.1268 2.6461 3.0840 1.5913 2.8789 4.6278 2.612329078 NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 0.00026003438 0.00081962191 -1.1276 2.1920 1.8272 1.6542 1.8278 2.1558 1.71725980 REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 5.4318099E-05 0.000196885599 -1.1280 1.6794 1.2910 1.0126 1.5616 1.2573 0.9078613037 LOC613037 nuclear pore complex interacting protein pseudogene 0.00829676168 0.018346111754 -1.1294 0.0909 0.1069 0.2093 0.2689 0.0137 0.2097414777 HCG18 HLA complex group 18 (non-protein coding) 0.00027461794 0.000860649876 -1.1302 0.3321 0.3321 0.3321 0.3970 0.3970 0.397027106 ARRDC2 arrestin domain containing 2 0.00038968409 0.001180031115 -1.1305 1.5316 2.3921 1.9376 1.3221 3.0988 1.5979390980 ZNF805 zinc finger protein 805 0.00050353648 0.001485648069 -1.1311 2.0107 1.8256 2.7125 1.6661 3.0325 3.202151642 MRPL48 mitochondrial ribosomal protein L48 4.2099029E-05 0.000155746802 -1.1316 2.1293 2.3545 1.5560 2.3598 3.5353 1.901710412 NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 0.00018789275 0.000607426816 -1.1318 1.5631 3.1940 7.0647 1.0553 2.9304 2.0435253832 ZDHHC20 zinc finger, DHHC-type containing 20 4.24082161E-05 0.000156827145 -1.1320 1.7226 2.0702 1.1850 1.9876 2.6774 1.69952273 FHL1 four and a half LIM domains 1 0.0101789165 0.021958578792 -1.1323 0.3357 0.5358 0.4423 0.4202 0.3551 0.379023608 MKRN1 makorin ring finger protein 1 0.00014490422 0.000480698969 -1.1329 1.0570 0.9643 0.7107 1.1441 1.1433 0.96545795 PTPRJ protein tyrosine phosphatase, receptor type, J 0.00020951116 0.000670788139 -1.1333 0.3468 0.5439 0.4707 0.4161 0.4032 0.77057805 LAPTM5 lysosomal protein transmembrane 5 0.00113916733 0.003130996601 -1.1340 1.8236 1.9086 1.5297 1.9980 2.3139 1.9658100190986 LOC100190986 uncharacterized LOC100190986 0.01497206431 0.030717444315 -1.1346 0.2927 0.0997 0.1028 0.3659 0.0428 0.213784064 HDHD2 haloacid dehalogenase-like hydrolase domain containing 2 0.00132714256 0.003589335225 -1.1350 2.4524 1.7001 2.1318 2.4684 2.1527 2.35685552 SRGN serglycin 0.00122274338 0.003334621935 -1.1355 2.4324 1.7472 1.8926 2.9278 2.5886 2.750556929 FEM1C fem-1 homolog c (C. elegans) 3.98501827E-05 0.000148297869 -1.1360 1.3955 2.1142 1.0781 2.0707 2.4091 1.828911214 AKAP13 A kinase (PRKA) anchor protein 13 0.00023647846 0.000750422784 -1.1368 1.3484 1.4355 1.4707 1.0312 1.1282 1.3171

55330 BLOC1S4 3.15928122E-05 0.000119491589 -1.1371 1.9428 1.8219 1.6152 2.0352 3.4426 2.0086317649 EIF4E3 eukaryotic translation initiation factor 4E family member 3 6.08531949E-05 0.000218449819 -1.1372 1.2836 1.9194 1.4676 1.0486 1.3900 1.2817819 CAMLG calcium modulating ligand 2.19990612E-05 8.59270729E-05 -1.1390 2.4687 1.4194 2.7707 2.3886 2.1175 3.316423765 IL17RA interleukin 17 receptor A 0.00419732713 0.010079322031 -1.1391 1.2098 1.9409 1.8963 1.3564 2.0929 2.149780184 CEP290 centrosomal protein 290kDa 0.02047903612 0.040266108677 -1.1407 0.2640 0.2484 0.1329 0.3236 0.0757 0.13366282 S100A11 S100 calcium binding protein A11 0.00897987862 0.019671543245 -1.1408 2.6865 2.2478 1.1598 2.8192 2.6087 1.78207879 RAB7A RAB7A, member RAS oncogene family 0.00012213601 0.000411975109 -1.1415 1.3728 1.1358 1.5588 1.2097 1.9075 1.68066840 SVIL supervillin 5.21961267E-05 0.000189683299 -1.1419 0.5564 0.8431 0.7210 0.4865 0.8395 0.60585440 POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 3.51291252E-05 0.000131883989 -1.1423 3.1428 2.1016 1.5302 3.8697 2.9701 2.1349170959 ZNF431 zinc finger protein 431 0.0177568361 0.035607211277 -1.1437 1.8582 1.9999 1.2541 1.6380 2.0227 1.75318398 PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.00313482317 0.007765657401 -1.1438 1.0478 0.8195 1.1197 0.6225 0.7555 1.1084642361 LOC642361 uncharacterized LOC642361 0.01432880824 0.029553672434 -1.1445 1.3451 2.1437 1.3242 1.3561 3.8281 2.016991664 ZNF845 zinc finger protein 845 0.01224251818 0.025774316424 -1.1467 1.5557 3.3035 1.9845 1.4314 4.2314 2.633011154 AP4S1 adaptor-related protein complex 4, sigma 1 subunit 0.01792528103 0.035897713163 -1.1481 3.0615 2.1558 1.3385 2.1506 1.7007 1.018611123 RCAN3 RCAN family member 3 0.00010218346 0.000350562566 -1.1482 2.6990 1.6532 2.1471 2.4762 1.2616 2.3596286053 NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 1.82849617E-05 7.26784467E-05 -1.1484 0.2547 0.3175 0.1951 0.2755 0.6808 0.076823600 AMACR alpha-methylacyl-CoA racemase 0.00846842849 0.0186787935 -1.1485 2.6589 1.9856 2.5309 2.4551 2.8234 2.62159488 PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.00159697017 0.004240023104 -1.1490 2.2813 3.2825 1.7700 2.6797 5.1709 2.895357659 ZBTB4 zinc finger and BTB domain containing 4 6.46169601E-05 0.000230827194 -1.1502 3.8294 7.5932 3.1934 2.4154 7.4096 3.925823741 EID1 EP300 interacting inhibitor of differentiation 1 0.00020229603 0.000650194017 -1.1513 6.2745 1.3491 0.3711 2.1805 1.3154 1.112758486 ZBED5 zinc finger, BED-type containing 5 2.33670255E-05 9.06886766E-05 -1.1521 2.0984 2.6701 1.5415 1.6890 1.8957 1.347923077 MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.00018723349 0.000605509796 -1.1542 0.5426 0.5790 0.8954 0.5759 0.9773 1.1499256987 SERINC5 serine incorporator 5 0.00145986043 0.003911800825 -1.1542 1.9447 2.9829 2.1076 2.5914 4.2651 3.2489246721 POLR2J2 DNA directed RNA polymerase II polypeptide J-related 1.27348224E-05 5.22900394E-05 -1.1552 1.1235 1.3044 1.2773 0.9480 1.3792 1.3790440689 HIST2H2BF histone cluster 2, H2bf 0.01028188782 0.022157171147 -1.1554 1.9394 3.4397 1.5128 1.3436 3.6874 1.411157212 TP73-AS1 TP73 antisense RNA 1 0.00012966687 0.000434968423 -1.1563 0.6666 0.8303 1.6429 0.5833 0.3708 1.25451385 CREB1 cAMP responsive element binding protein 1 3.03218135E-05 0.000115106998 -1.1563 0.7146 2.3847 1.0817 0.9828 3.7238 1.4928

79695 GALNT12 0.02316339512 0.04478601595 -1.1566 1.6023 1.8427 1.7671 1.0519 2.3141 1.58659063 PIAS2 protein inhibitor of activated STAT, 2 0.00451457141 0.010752117937 -1.1600 4.4170 1.1585 2.1917 1.7091 0.3799 2.526484910 TMEM87B transmembrane protein 87B 0.00013145144 0.000439936585 -1.1604 1.2584 1.9336 1.1325 1.3406 2.2112 3.180054790 TET2 tet methylcytosine dioxygenase 2 0.00046888412 0.001391949753 -1.1606 1.1384 0.8292 1.0286 1.2489 1.2737 1.25738609 KLF7 Kruppel-like factor 7 (ubiquitous) 0.00611357266 0.014015959805 -1.1608 1.3547 1.3143 1.0946 1.2589 1.4708 1.19339130 FAM50A family with sequence similarity 50, member A 1.82623789E-05 7.26202803E-05 -1.1614 0.8968 1.9322 1.4457 1.0164 1.3701 1.703910199 MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 8.69894452E-05 0.000303160622 -1.1616 14.1191 30.9122 0.9894 7.4927 18.1267 1.736525942 SIN3A SIN3 transcription regulator family member A 0.00016571633 0.000542063859 -1.1648 1.5651 3.0777 2.1273 1.6586 3.7401 3.234410313 RTN3 reticulon 3 0.00164431885 0.004352432974 -1.1652 1.8428 2.5582 1.8829 1.6947 2.9600 2.3687

64780 MICAL1 0.00059415352 0.001726522453 -1.1657 1.0155 1.1584 1.1339 0.7896 0.7304 1.17274163 MCC mutated in colorectal cancers 0.01830486963 0.036549729859 -1.1675 1.1276 2.1497 1.2320 1.0882 1.5052 1.10304077 NBR1 neighbor of BRCA1 gene 1 0.000108335 0.000369584964 -1.1690 1.8813 1.4101 1.8311 1.5905 1.6265 1.572957184 FAM219B family with sequence similarity 219, member B 0.00011852425 0.000400976698 -1.1692 2.5017 1.7157 1.8826 2.3396 2.3735 2.18564750 NEK1 NIMA-related kinase 1 0.00523956054 0.012259860435 -1.1701 1.1550 1.0465 0.9394 1.0085 1.4904 1.08399414 TJP2 tight junction protein 2 0.01670312975 0.03373126654 -1.1703 0.7278 0.7787 0.8998 0.5972 0.7343 0.77678932 MBD2 methyl-CpG binding domain protein 2 0.00014275106 0.000474762912 -1.1725 1.7352 1.5139 1.2307 1.7298 0.8621 1.24399840 TESPA1 thymocyte expressed, positive selection associated 1 0.000100898 0.0003466592 -1.1734 2.7682 1.8670 1.9247 2.2611 1.7930 1.67529583 ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 8.86135164E-06 3.76458073E-05 -1.1745 1.8422 1.9083 1.5543 1.5045 2.4506 1.717284316 LSMD1 LSM domain containing 1 0.00014057712 0.000468129253 -1.1753 1.3619 3.0971 2.0381 0.5762 1.9201 1.7653643836 ZFP62 ZFP62 zinc finger protein 0.00087269014 0.002456979091 -1.1770 1.5615 2.8653 1.8667 1.3347 2.6042 2.49505579 PRKCB protein kinase C, beta 0.00011529402 0.000390699616 -1.1775 1.5577 1.2876 1.7935 0.9619 1.0636 2.14927316 UBC ubiquitin C 1.26008941E-06 6.42241385E-06 -1.1787 2.1688 1.2705 2.5023 2.6221 1.8789 2.905423355 VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 0.00034921374 0.001068279509 -1.1791 0.6780 0.8842 0.8361 0.7106 1.0025 0.952022872 SEC31A SEC31 homolog A (S. cerevisiae) 0.00012240006 0.000412789569 -1.1795 0.5936 0.8423 0.5742 0.6928 1.2224 0.85158721 EDF1 endothelial differentiation-related factor 1 0.00010684265 0.000364834418 -1.1802 1.4808 3.1480 1.7495 1.0978 3.5369 1.700384248 FYTTD1 forty-two-three domain containing 1 1.19239547E-05 4.92817237E-05 -1.1822 2.6463 3.8777 1.5849 2.8490 3.8516 2.13796193 RPS5 ribosomal protein S5 1.03272455E-05 4.32400158E-05 -1.1826 2.3536 3.9874 4.3822 1.9113 3.3237 2.4066255967 PAN3 PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae) 7.35592849E-06 3.18199634E-05 -1.1842 1.8986 2.4494 1.0799 1.5536 2.2196 1.412623499 MACF1 microtubule-actin crosslinking factor 1 8.57562949E-05 0.000299262609 -1.1868 0.3882 0.3914 0.4590 0.3988 0.3795 0.4827175 AGA aspartylglucosaminidase 7.98882273E-05 0.000280768934 -1.1871 1.4564 1.8575 1.1383 1.3549 2.1898 1.36535279 PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.00039842095 0.001204890353 -1.1885 1.8360 2.2038 1.3117 1.9045 2.2371 1.333755973 BCAP29 B-cell receptor-associated protein 29 9.31336608E-05 0.000321933078 -1.1892 1.6991 1.1684 1.3560 1.1127 1.5184 1.62002217 FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.02620292138 0.049800268295 -1.1894 0.6583 0.5518 0.6153 0.5547 0.3686 0.4616120534 ARL14EP chromosome 11 open reading frame 46 2.81216283E-05 0.000107487325 -1.1902 1.9983 1.2169 1.5698 1.4714 1.4099 1.75926468 FBXW4 F-box and WD repeat domain containing 4 2.00426004E-05 7.89263783E-05 -1.1904 1.9433 1.9312 1.6016 1.9684 3.2659 2.223664750 SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00022053262 0.000702750619 -1.1907 2.1858 1.6084 1.6649 2.0099 2.2607 2.084527107 ZBTB11 zinc finger and BTB domain containing 11 7.61608421E-06 3.28597617E-05 -1.1914 1.6803 1.4883 0.9873 1.1265 1.2102 0.8406728642 CDK11A cell division cycle 2-like 2 (PITSLRE proteins) 0.00012910331 0.000433237051 -1.1919 0.2383 0.1924 0.5807 1.2966 0.5863 1.027426036 ZNF451 zinc finger protein 451 6.23140965E-06 2.73308491E-05 -1.1924 1.7082 2.3330 1.6116 1.3694 2.9784 1.709955623 THUMPD1 THUMP domain containing 1 2.32589434E-05 9.03075679E-05 -1.1926 1.2417 1.3700 0.8612 1.4138 1.7142 1.139151002 TPRKB TP53RK binding protein 0.00108925359 0.003003295836 -1.1928 1.3204 1.3628 0.9454 1.5568 2.1605 1.15377690 ZNF131 zinc finger protein 131 1.47051276E-05 5.9537357E-05 -1.1929 1.7741 1.3731 1.5662 1.7311 1.8462 2.06025885 RAD21 RAD21 homolog (S. pombe) 8.98333502E-05 0.000311763528 -1.1930 0.2735 0.3186 0.1259 0.2901 1.4112 1.484857446 NDRG3 NDRG family member 3 0.00061874674 0.001790299351 -1.1932 2.8637 1.2271 1.7917 2.0706 1.0466 2.1282494115 RBMXL1 RNA binding motif protein, X-linked-like 1 1.02117121E-05 4.28544795E-05 -1.1945 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970163049 ZNF791 zinc finger protein 791 0.00427783489 0.010245720167 -1.1967 19.9911 31.4778 0.6711 12.7055 33.2204 0.341257498 KIDINS220 kinase D-interacting substrate, 220kDa 7.75079668E-06 3.33700652E-05 -1.1982 0.7924 0.7096 0.4908 0.7774 1.3488 0.604564864 RFX7 regulatory factor X, 7 1.04359431E-05 4.36351378E-05 -1.1992 0.8797 1.3070 0.5688 0.8458 1.2852 0.8870100132288 TEKT4P2 tektin 4 pseudogene 2 0.00326079741 0.00803632186 -1.1994 1.0814 1.2460 0.8450 1.1946 1.5750 1.07558554 PIAS1 protein inhibitor of activated STAT, 1 2.23803925E-05 8.73045543E-05 -1.1995 1.7932 2.3079 1.7943 1.7132 2.2462 2.368255793 FAM63A family with sequence similarity 63, member A 0.01357445823 0.028214367057 -1.1999 2.7461 2.5815 2.9877 2.2626 2.1344 2.1945116068 LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3 0.00013414982 0.00044778691 -1.2000 2.4928 2.5323 1.5690 2.4623 3.4574 2.62076171 RPL41 ribosomal protein L41 1.58925162E-05 6.3962127E-05 -1.2008 2.7588 3.4279 1.4528 4.5120 6.3858 2.435451691 NAA38 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) 5.54952198E-06 2.46417656E-05 -1.2016 2.4213 4.0771 1.5410 3.0031 5.3288 2.685327335 EIF3K eukaryotic translation initiation factor 3, subunit K 5.60883705E-05 0.000202659028 -1.2017 2.9097 2.2272 2.2384 3.1442 5.8672 2.905223325 KIAA1033 KIAA1033 0.00033797422 0.001038242249 -1.2036 1.3775 1.2439 0.7717 1.1986 1.7849 1.10163695 ITGB7 integrin, beta 7 0.00284364853 0.007106982063 -1.2040 1.7855 1.2611 1.8558 1.0816 0.7783 1.148864429 ZDHHC6 zinc finger, DHHC-type containing 6 1.2287503E-05 5.06239581E-05 -1.2045 2.1777 2.2847 1.2422 1.4130 1.7041 0.85025991 RFX3 regulatory factor X, 3 (influences HLA class II expression) 0.0187120236 0.037273094435 -1.2061 0.9411 1.3175 0.9022 1.3643 1.8871 1.7438

9187 SLC24A1 0.02022955511 0.039844177105 -1.2070 0.2833 0.8868 0.2003 0.7780 0.6423 0.14537733 ZNF180 zinc finger protein 180 0.01581177432 0.032172910956 -1.2073 2.2990 1.0876 1.2339 2.7832 1.5179 1.66042157 F8 coagulation factor VIII, procoagulant component 0.02176469312 0.04245137411 -1.2076 0.9226 1.0583 1.4353 0.8862 0.4956 2.247279609 METTL21D chromosome 14 open reading frame 138 0.01446853076 0.029811569027 -1.2081 1.8317 1.3939 1.4652 1.5183 1.2591 0.974723512 SUZ12 SUZ12 polycomb repressive complex 2 subunit 3.23151977E-05 0.000121946157 -1.2087 1.9097 1.0800 1.8760 1.9863 2.2599 1.855654664 TMEM106B transmembrane protein 106B 8.98934888E-06 3.81275262E-05 -1.2088 1.8699 2.5362 2.0349 2.1311 2.0853 2.199065258 MPPE1 metallophosphoesterase 1 0.00035278792 0.001077409487 -1.2092 1.4822 2.6449 1.4353 1.7164 2.3143 1.799911235 PDCD10 programmed cell death 10 1.28581145E-05 5.27607159E-05 -1.2092 2.3507 2.7573 1.6787 1.8007 3.5523 2.537851347 TAOK3 TAO kinase 3 1.31861982E-05 5.39857078E-05 -1.2094 1.2338 1.1504 0.8162 1.0486 1.3626 0.9237348235 SKA2 family with sequence similarity 33, member A 1.09700125E-05 4.56696443E-05 -1.2099 0.5465 3.5295 2.1828 1.3422 11.1735 3.10279685 CLINT1 clathrin interactor 1 2.26547872E-05 8.82618918E-05 -1.2105 0.7979 0.8644 0.5938 0.7680 0.9726 0.64048573 CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 6.36526718E-05 0.000227649563 -1.2112 0.7868 1.1425 0.6810 0.9605 1.3087 0.940655082 ARGLU1 arginine and glutamate rich 1 0.0002086716 0.000668568746 -1.2115 1.8506 1.6179 1.6018 1.2785 1.6113 1.7186998 CDC42 cell division cycle 42 4.67785E-05 0.000171599428 -1.2116 1.4938 1.2049 0.9269 1.7821 1.1713 1.4887440423 SUZ12P1 suppressor of zeste 12 homolog pseudogene 1 0.02003276489 0.039507682688 -1.2120 1.6933 2.4505 1.6439 1.5073 3.0985 1.9645729877 TBC1D3H TBC1 domain family, member 3H 0.01683184155 0.033961065459 -1.2122 0.0139 0.0839 0.0906 0.1653 0.0755 0.09525189 PEX1 peroxisomal biogenesis factor 1 0.00054623996 0.001598477975 -1.2124 2.1487 3.8178 0.9999 1.9115 1.1695 0.649255186 SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier ), member 36 5.51446399E-06 2.44980029E-05 -1.2125 1.2365 2.5862 1.6941 1.3244 3.8538 2.66831822 ATN1 desmocollin 1 1.44691058E-05 5.8711859E-05 -1.2126 0.7351 2.2960 1.5196 0.6839 1.7275 1.03324696 NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 2.98094683E-05 0.000113285899 -1.2127 0.3234 4.1300 2.1660 0.3571 7.4628 0.709036 ACADSB acyl-CoA dehydrogenase, short/branched chain 0.00033768376 0.001037873454 -1.2139 3.8622 4.8250 1.6296 1.6339 2.1886 0.344923174 ZCCHC14 zinc finger, CCHC domain containing 14 0.00133790925 0.003616313284 -1.2146 0.5794 1.4104 1.1628 0.3764 0.7968 1.2004

10962 MLLT11 0.00249247594 0.006320960505 -1.2156 0.2881 0.2895 0.3285 0.4318 0.4241 0.372379758 DHRS12 dehydrogenase/reductase (SDR family) member 12 0.02588677902 0.049286571451 -1.2156 2.6106 2.2797 2.2023 1.9888 2.5341 2.259256922 MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 1.2102495E-05 4.99518386E-05 -1.2156 1.5558 1.9607 1.6682 1.2753 1.9009 1.545555788 LMBRD1 LMBR1 domain containing 1 5.02569203E-05 0.000183182615 -1.2158 1.2853 1.5702 0.7989 1.1723 1.1512 0.7780378805 MKLN1-AS1 MKLN1 antisense RNA 1 (head to head) 0.00558107553 0.012942938454 -1.2169 2.2845 3.0277 1.5466 2.4944 3.7645 3.0549399671 HEATR4 HEAT repeat containing 4 0.02490827337 0.047710568019 -1.2173 0.0387 0.0965 0.2117 0.1381 0.0418 0.2690868 CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase 0.00032865542 0.001012509159 -1.2175 0.9426 1.3221 1.0659 1.2044 1.7149 1.874326986 PABPC1 poly(A) binding protein, cytoplasmic 1 3.98585597E-06 1.81982909E-05 -1.2187 2.3151 6.0874 1.4991 2.2281 10.2424 2.9899

Q9NUP1,biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)

microtubule associated monooxygenase, calponin and LIM domain containing 1

solute carrier family 24 (sodium/potassium/calcium exchanger), member 1

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11

23023 TMCC1 transmembrane and coiled-coil domain family 1 0.00028029506 0.000876527712 -1.2193 1.5658 0.7574 0.8366 1.4400 0.5817 0.619555030 FBXO34 F-box protein 34 1.97774518E-05 7.7949439E-05 -1.2193 1.6934 0.8642 1.2471 1.4893 1.3504 1.5240132949 AASDH 2-aminoadipic 6-semialdehyde dehydrogenase 0.01136961056 0.024156456302 -1.2205 1.8212 1.5954 1.0792 1.8966 1.3342 1.53855533 PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 4.41444112E-06 1.99902523E-05 -1.2238 0.9837 1.1242 0.8909 1.0129 1.6169 1.2330114885 OSBPL11 oxysterol binding protein-like 11 4.10307158E-05 0.000152318821 -1.2251 2.7092 3.0560 1.7928 2.1610 4.0109 2.5439283450 HECTD4 chromosome 12 open reading frame 51 5.85571579E-06 2.58568484E-05 -1.2268 0.5423 0.8356 0.8404 0.5158 0.7246 0.95919765 ZFYVE16 zinc finger, FYVE domain containing 16 0.01391241665 0.02880540249 -1.2270 0.6262 0.5224 0.5126 0.7540 0.6761 0.726890806 ANGEL2 angel homolog 2 (Drosophila) 1.07603478E-05 4.48785837E-05 -1.2272 1.3595 1.6679 1.2042 1.3142 1.5102 1.5132440574 MINOS1 mitochondrial inner membrane organizing system 1 1.37433468E-05 5.60564394E-05 -1.2275 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970689 BTF3 basic transcription factor 3 4.0122252E-06 1.83003941E-05 -1.2287 1.7759 2.3279 2.4845 1.8300 4.0042 3.381811237 RNF24 ring finger protein 24 0.00279087897 0.006992313252 -1.2287 1.6368 1.5723 1.3874 1.2041 1.4272 1.411723317 DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 3.52392722E-06 1.63134528E-05 -1.2289 1.1479 1.3201 0.9748 1.2200 1.8811 1.562723142 DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 0.00409884654 0.009863574873 -1.2290 1.6268 3.6069 1.2624 1.8077 3.5686 2.16967791 ZYX zyxin 7.29316961E-05 0.000257957404 -1.2296 0.6741 1.6404 1.0281 0.7815 1.5962 1.46244774 NFIA nuclear factor I/A 0.01823980022 0.036434308794 -1.2306 0.9467 1.2584 0.8970 0.8428 0.8195 0.885611043 MID2 midline 2 0.00161579815 0.004285031021 -1.2309 1.4857 1.2465 1.3701 1.4330 1.5974 1.36984155 MBP myelin basic protein 0.00014567128 0.000482892908 -1.2325 0.2980 0.6906 0.7180 0.4047 0.9762 0.817857532 NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 4.8656271E-05 0.000177916227 -1.2328 3.5451 2.0142 1.9062 3.7070 2.8738 2.777023387 SIK3 SIK family kinase 3 4.49735367E-06 2.03254134E-05 -1.2348 1.0594 0.9923 0.7576 1.0203 0.8964 0.7100219749 ZNF25 zinc finger protein 25 0.02422547037 0.046628862797 -1.2353 1.9331 1.5799 1.6866 1.8372 1.5632 1.690460685 ZFAND3 zinc finger, AN1-type domain 3 0.00152098644 0.004058925685 -1.2372 2.5033 2.2957 1.5291 2.4542 3.6147 2.577579632 FAM184A family with sequence similarity 184, member A 0.01467649394 0.030175413228 -1.2375 0.8524 0.6044 0.7715 0.7099 0.4696 0.83443631 INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 1.32202329E-05 5.41129248E-05 -1.2378 2.3117 3.0819 1.9254 2.1104 2.8202 2.3435387119 CEP85L chromosome 6 open reading frame 204 3.82695696E-06 1.75693863E-05 -1.2385 1.6128 3.2682 1.9109 1.6410 2.7116 2.0525

5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 6.54129945E-05 0.000233442624 -1.2406 2.4307 1.9187 1.3802 3.0455 3.9345 2.775622908 SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 1.0317576E-05 4.32292475E-05 -1.2407 2.2930 1.2323 1.0269 2.1607 1.0861 2.366254940 OCIAD1 OCIA domain containing 1 2.95980217E-05 0.000112582718 -1.2425 1.9541 3.6331 1.3194 2.1767 5.6494 1.948055916 NXT2 nuclear transport factor 2-like export factor 2 0.00045546071 0.001355845256 -1.2438 2.0280 1.7945 1.1839 1.5522 3.2667 1.0539119385 AGAP11 KIAA1975 protein similar to MRIP2 0.02531063306 0.048360962804 -1.2440 0.6809 0.5899 0.9524 0.5063 0.4566 0.870751422 PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 5.87751569E-06 2.59405717E-05 -1.2441 0.5972 1.0248 0.6016 0.4053 0.9018 0.691564773 PCED1A PC-esterase domain containing 1A 0.00257712066 0.006514824105 -1.2442 0.9035 2.3241 1.6695 0.3670 1.0200 0.7890339500 ZNF678 zinc finger protein 678 0.01642559098 0.0332589094 -1.2443 1.6199 0.9474 1.1420 1.6964 1.3289 1.977755432 YOD1 YOD1 deubiquitinase 0.00026428016 0.000831856513 -1.2443 2.0544 2.3890 2.1235 2.4932 3.3128 2.34401241 LTB4R leukotriene B4 receptor 0.00542918225 0.012636482434 -1.2448 1.3320 1.4070 1.3458 1.0190 1.0520 0.6254134957 STXBP5 syntaxin binding protein 5 (tomosyn) 2.10607479E-05 8.26152823E-05 -1.2456 1.6576 0.8661 0.7773 1.3053 0.9703 0.7130729852 RPA3-AS1 RPA3 antisense RNA 1 0.00058414054 0.001700129979 -1.2457 2.4644 1.4351 1.6047 2.9829 2.3530 3.16439751 SNPH syntaphilin 0.00309393005 0.007673719273 -1.2459 2.3647 1.8636 1.9209 1.3076 1.1013 1.233554460 MRPS21 mitochondrial ribosomal protein S21 3.04821676E-05 0.00011567397 -1.2460 2.0142 2.0681 2.2746 1.8835 2.1446 2.354184815 MGC12916 uncharacterized protein MGC12916 0.00901099484 0.019730245373 -1.2470 2.2027 3.2651 2.6318 1.0854 3.3764 2.207955758 RCOR3 REST corepressor 3 1.72027106E-05 6.87656812E-05 -1.2471 0.9603 0.9698 1.0860 1.0531 1.4460 2.082264145 ZFYVE20 zinc finger, FYVE domain containing 20 5.39590148E-05 0.000195778221 -1.2497 2.6240 1.6132 2.4896 2.6348 2.2071 3.03217903 ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 1.68023714E-05 6.73421651E-05 -1.2508 2.2391 3.0415 1.7900 2.1001 3.1999 2.50039778 KIAA0232 KIAA0232 4.92820884E-06 2.21466385E-05 -1.2516 0.9207 2.5326 1.3530 1.0570 3.8144 2.5694129450 TYW5 tRNA-yW synthesizing protein 5 0.00375203063 0.009113000612 -1.2524 3.5408 2.5209 2.9764 3.0384 2.0257 2.603980216 ALPK1 alpha-kinase 1 0.02453772393 0.047135543695 -1.2524 1.1080 0.7258 0.4785 0.9481 0.6076 0.52436415 SEPW1 selenoprotein W, 1 1.80744742E-05 7.19356985E-05 -1.2525 2.2119 3.0663 1.6041 1.7377 3.6849 2.307491316 GUSBP11 glucuronidase, beta pseudogene 11 0.00267793223 0.006743547089 -1.2526 0.5073 0.5341 1.0312 0.4898 0.4029 0.915323262 PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2.36871629E-06 1.13715349E-05 -1.2541 0.9518 1.7283 0.4412 0.3321 1.1183 0.220222875 ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00018912816 0.000611204415 -1.2547 2.0439 2.2338 2.6967 2.0828 3.1315 2.916351088 KLHL5 kelch-like family member 5 3.77819524E-05 0.000141234009 -1.2550 1.5651 1.7285 1.1432 1.1443 1.2896 1.162510168 ZNF197 zinc finger protein 197 0.00510649686 0.011996131469 -1.2568 1.9985 1.0680 1.7275 2.4496 1.6265 1.87894659 PPP1R12A protein phosphatase 1, regulatory subunit 12A 2.86430305E-05 0.00010919371 -1.2574 0.9423 0.9139 0.7712 0.9526 1.1468 1.281526271 FBXO5 F-box protein 5 7.78914619E-05 0.000274384575 -1.2577 2.1261 1.7119 1.5346 2.0492 2.9197 2.9995100506334 LINC00649 long intergenic non-protein coding RNA 649 0.00658745133 0.014982065064 -1.2580 1.5340 2.6425 1.3859 1.9607 3.3075 1.72951611 DAP death-associated protein 6.58802195E-05 0.000234972354 -1.2581 2.0654 3.5885 1.4507 2.0630 4.3637 1.45984709 NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 2.83012603E-06 1.33450485E-05 -1.2583 8.6240 7.6423 0.2254 0.3871 0.9478 0.438551244 CCDC174 coiled-coil domain containing 174 0.00029351626 0.000913339429 -1.2588 1.3911 2.1872 1.3397 1.6015 2.9951 1.598856731 SLC2A4RG SLC2A4 regulator 0.00057321993 0.001671540787 -1.2589 1.1917 1.7304 1.5745 0.9745 1.7115 1.271823505 TMEM131 transmembrane protein 131 2.34967107E-06 1.12922646E-05 -1.2592 1.5485 2.1357 1.1224 1.4639 3.0051 1.726526993 AKAP8L A kinase (PRKA) anchor protein 8-like 2.44566583E-06 1.17135534E-05 -1.2594 0.8345 1.2653 1.0312 0.7634 1.2447 1.17769611 NCOR1 nuclear receptor corepressor 1 4.77366799E-05 0.000174757163 -1.2599 0.3324 0.8214 0.4814 0.4205 1.3462 0.631422838 RNF44 ring finger protein 44 2.84733971E-05 0.000108637693 -1.2600 1.2579 1.8537 1.9064 1.2057 1.5241 1.8087151636 DTX3L deltex 3-like (Drosophila) 0.01887026222 0.037535100284 -1.2603 0.3321 0.3321 0.3321 0.3970 0.3970 0.397057571 CARNS1 KIAA1394 protein 0.02448482695 0.047043823139 -1.2618 1.0482 1.0446 1.3747 0.5920 1.0045 0.874455906 ZC4H2 zinc finger, C4H2 domain containing 0.01024172689 0.022081665052 -1.2619 2.1711 2.2056 1.4430 2.0941 2.5771 1.8546

51000 SLC35B3 0.00405632241 0.009770250872 -1.2623 2.7829 2.9502 2.0698 1.3545 4.4734 1.2730284802 FRG1B similar to FRG1 protein (FSHD region gene 1 protein) 0.00059976557 0.001740339283 -1.2629 0.4265 0.3849 0.3631 0.5212 0.4299 0.3950388558 ZNF808 zinc finger protein 808 0.00147524503 0.003948971172 -1.2633 2.7798 3.8423 1.9309 3.1407 2.5791 2.9465137886 UBXN2B UBX domain protein 2B 0.00020928769 0.000670190109 -1.2645 2.6833 3.8101 1.6694 2.2896 3.6601 1.8462100129387 GABPB1-AS1 GABPB1 antisense RNA 1 0.01707710338 0.034387880585 -1.2653 2.9455 3.2191 0.6360 2.9287 7.6368 0.841354904 WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 2.42110414E-05 9.35840204E-05 -1.2665 0.8197 1.3123 1.0661 1.1000 2.4815 1.889851719 CAB39 calcium binding protein 39 4.36630819E-05 0.000161206674 -1.2669 1.1892 1.6020 1.1602 1.1871 2.8360 1.4405151827 LRRC34 leucine rich repeat containing 34 0.02198172866 0.042797032075 -1.2687 2.6730 2.0394 2.4289 1.7183 1.6134 2.43154084 MXD1 MAX dimerization protein 1 0.00202888213 0.005253186108 -1.2701 1.6314 3.7838 1.3997 1.8058 4.8090 2.14357388 UQCRH ubiquinol-cytochrome c reductase hinge protein 1.75106441E-05 6.98438089E-05 -1.2703 3.3978 3.6301 2.7330 1.9939 2.7170 1.5952192669 AGO3 eukaryotic translation initiation factor 2C, 3 0.00012074971 0.000407750647 -1.2703 2.3033 1.8899 1.4027 1.8588 2.0614 2.30731176 AP3S1 adaptor-related protein complex 3, sigma 1 subunit 5.10918226E-06 2.28643101E-05 -1.2709 3.9792 29.9753 1.5265 4.2150 9.0582 1.4175167153 PAPD4 PAP associated domain containing 4 4.53845689E-06 2.0485841E-05 -1.2719 2.2491 1.9436 1.6092 2.7112 2.2922 2.4028400966 RGPD1 RANBP2-like and GRIP domain containing 1 2.33547361E-05 9.06602377E-05 -1.2721 0.1291 0.1479 0.1997 0.3920 0.2792 0.218180298 MTERFD3 MTERF domain containing 3 0.02307427203 0.044634035416 -1.2723 1.1840 1.3966 0.9460 1.0772 1.2783 0.753826235 FBXL4 F-box and leucine-rich repeat protein 4 0.00242992734 0.006182070786 -1.2729 1.2836 1.0937 0.7325 1.1031 1.9596 1.13941647 GADD45A growth arrest and DNA-damage-inducible, alpha 0.00323389402 0.007976472948 -1.2737 1.5929 4.0939 2.1395 1.5815 5.2369 3.04229712 USP6NL USP6 N-terminal like 0.01920630405 0.038103972602 -1.2750 1.3128 1.9850 1.5332 0.9446 1.9129 1.4158

6883 TAF12 1.93452671E-06 9.48167167E-06 -1.2758 2.8506 2.0869 2.3259 2.8955 3.7638 3.446130061 SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.00696192742 0.015712492323 -1.2759 1.1880 0.9260 0.8843 1.3482 1.1058 0.88353298 HSF2 heat shock transcription factor 2 5.64938521E-05 0.000204014036 -1.2761 1.1336 1.7677 1.0584 1.2232 1.4473 1.67958409 UXT ubiquitously-expressed, prefoldin-like chaperone 1.96904798E-05 7.76401484E-05 -1.2769 0.3548 1.3803 0.2389 0.4973 3.4114 0.224023092 ARHGAP26 Rho GTPase activating protein 26 0.02390451129 0.046083902754 -1.2773 1.7428 1.1852 1.5398 1.3711 1.8026 2.522310746 MAP3K2 mitogen-activated protein kinase kinase kinase 2 3.50026554E-06 1.62162404E-05 -1.2779 0.3179 0.3026 0.1930 0.3575 0.2303 0.279055171 TBCCD1 TBCC domain containing 1 0.00063328583 0.001828602825 -1.2782 1.8727 1.7749 2.4156 1.7382 2.4716 2.49245163 PDK1 pyruvate dehydrogenase kinase, isozyme 1 0.00074408272 0.002120711193 -1.2786 1.8879 1.9390 1.5056 2.0684 2.8783 1.8570157680 VPS13B vacuolar protein sorting 13 homolog B (yeast) 2.49891046E-06 1.19341589E-05 -1.2794 1.5486 0.9209 0.7561 1.6897 1.3778 1.515580321 CEP70 centrosomal protein 70kDa 0.01849761394 0.036902325794 -1.2828 1.1437 1.3738 1.1774 1.0437 1.3068 1.17922339 FNTA farnesyltransferase, CAAX box, alpha 6.02688463E-06 2.649741E-05 -1.2839 2.0265 1.9644 1.8380 2.0670 2.9620 2.75245108 PCM1 pericentriolar material 1 1.95290213E-05 7.70367612E-05 -1.2843 0.5379 0.6775 0.3608 0.5486 0.5546 0.55897562 ZNF708 zinc finger protein 708 0.00822633273 0.01821516621 -1.2851 1.6410 1.5758 1.3912 1.8403 1.5182 2.066522841 RAB11FIP2 RAB11 family interacting protein 2 (class I) 0.00105790575 0.002923038548 -1.2851 2.0690 2.7482 2.1812 1.1736 1.9297 2.124779991 OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 1.38105568E-06 6.98633704E-06 -1.2857 1.9184 3.2010 2.4364 1.5989 4.0971 2.0772100506548 LOC100506548 uncharacterized LOC100506548 0.00036073446 0.001099526032 -1.2864 0.1858 0.9885 0.6125 0.3986 0.6839 0.391079670 ZCCHC6 zinc finger, CCHC domain containing 6 2.24432057E-06 1.08258251E-05 -1.2871 0.9850 0.8381 1.0074 0.7755 0.9011 1.062183982 IFI27L2 interferon, alpha-inducible protein 27-like 2 2.86612195E-06 1.35043271E-05 -1.2872 1.8096 1.7658 1.9816 1.1714 1.4535 1.780327010 TPK1 thiamin pyrophosphokinase 1 0.00412055869 0.009913212433 -1.2887 0.6044 1.4207 0.4901 0.8172 1.3729 0.778156477 CCL28 chemokine (C-C motif) ligand 28 0.02479041952 0.047526025126 -1.2893 0.8387 1.2872 0.9879 0.8750 1.4607 1.008955188 RIC8B RIC8 guanine nucleotide exchange factor B 0.00260606335 0.006581615703 -1.2905 0.2546 0.4093 1.1585 0.4399 0.2126 0.260322883 CLSTN1 calsyntenin 1 1.29646674E-05 5.3138269E-05 -1.2918 0.6467 0.7049 0.8718 0.5693 0.4423 0.76427006 TEC tec protein tyrosine kinase 0.02291390079 0.044366090413 -1.2932 2.1816 3.2728 1.3667 1.6565 2.4941 2.28179166 EBAG9 estrogen receptor binding site associated, antigen, 9 0.00083061463 0.002347925509 -1.2933 2.4930 3.7270 1.6664 1.9171 4.1950 1.9135119392 SFR1 SWI5-dependent recombination repair 1 0.01258227287 0.026398356851 -1.2933 2.0151 3.0739 1.9115 2.0534 3.5660 2.25729284 NPIPA1 nuclear pore complex interacting protein family, member A1 0.00323526542 0.007978778474 -1.2943 0.2190 0.2544 0.2811 0.2302 0.1301 0.265250804 MYEF2 myelin expression factor 2 0.00566376406 0.013121376557 -1.2952 0.6036 0.9709 0.4445 0.5243 0.8173 0.640910855 HPSE heparanase 0.00068024547 0.001949716905 -1.2956 1.2140 0.9373 1.6684 0.9476 0.8063 1.41889147 NEMF nuclear export mediator factor 1.6466572E-06 8.19828893E-06 -1.2956 0.8199 0.7865 0.6311 1.0448 1.1952 1.05894690 NCK1 NCK adaptor protein 1 5.55452603E-06 2.46579931E-05 -1.2962 1.2867 2.7998 0.9594 1.0771 3.4302 1.442325957 PNISR PNN-interacting serine/arginine-rich protein 1.12587369E-06 5.79655227E-06 -1.2975 2.7336 1.8659 1.5491 3.7208 3.4955 3.5654169981 SPIN3 spindlin family, member 3 0.01901368886 0.03777105053 -1.2994 1.9112 3.1667 1.2991 1.8316 1.4468 1.35744089 SMAD4 SMAD family member 4 5.27948944E-06 2.35629778E-05 -1.2999 0.9736 0.7811 0.9044 0.9902 1.1166 1.1651359845 FAM101B family with sequence similarity 101, member B 0.00014336011 0.000476190897 -1.3007 0.6082 0.4409 0.5976 0.6184 0.6086 0.3052147172 LRRC37BP1 leucine rich repeat containing 37B pseudogene 1 0.00183190657 0.004784533557 -1.3010 0.0981 0.0797 0.1328 0.1882 0.0863 0.21083621 ING1 inhibitor of growth family, member 1 9.6342984E-07 5.02965429E-06 -1.3017 1.8672 3.2996 1.6811 1.6916 4.4373 2.80524205 MEF2A myocyte enhancer factor 2A 3.39003995E-06 1.57495067E-05 -1.3020 0.7123 0.8569 0.4691 0.8918 1.0888 0.71891655 DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 3.89446141E-06 1.784343E-05 -1.3022 1.6898 1.7934 1.5417 2.1862 2.2237 1.949755063 ZCWPW1 zinc finger, CW type with PWWP domain 1 0.01867778678 0.037213010582 -1.3028 0.8735 0.1461 0.2989 0.7147 0.0696 0.32063983 ABLIM1 actin binding LIM protein 1 2.42759676E-05 9.37781142E-05 -1.3028 1.0782 1.0063 0.9564 0.8861 0.6163 0.69794053 LTBP2 latent transforming growth factor beta binding protein 2 0.01788771118 0.035838186253 -1.3030 2.8955 2.9308 1.4923 2.0046 1.7768 1.52036500 SKP1 S-phase kinase-associated protein 1 2.61018434E-05 0.000100343548 -1.3034 2.2978 2.5496 1.1634 2.9792 5.0892 2.117855727 BTBD7 BTB (POZ) domain containing 7 2.36908159E-05 9.17798771E-05 -1.3045 2.7200 0.5972 1.3680 1.5152 0.4829 1.985680124 VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 4.93531529E-06 2.21622219E-05 -1.3046 2.8278 4.0703 2.7631 2.2816 8.7900 3.64259230 RAB11B RAB11B, member RAS oncogene family 1.03354869E-06 5.36810737E-06 -1.3066 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970284996 RNF149 ring finger protein 149 1.20230821E-05 4.96577207E-05 -1.3081 3.7007 3.6211 2.0559 5.1659 5.9735 3.8417170691 ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 0.01810801717 0.03619622467 -1.3088 0.5892 0.6839 0.5470 0.5450 0.5472 0.524851187 RSL24D1 ribosomal L24 domain containing 1 4.7744514E-05 0.000174757163 -1.3094 2.7705 2.9633 1.4641 2.6974 4.3083 2.987656947 MFF mitochondrial fission factor 2.11243473E-06 1.02491788E-05 -1.3098 0.4905 0.3903 0.2455 0.4044 0.3843 0.209751130 ASB3 ankyrin repeat and SOCS box containing 3 4.50604717E-05 0.000165863203 -1.3099 1.0967 1.8448 1.6719 1.0912 0.9877 1.17957570 ZNF22 zinc finger protein 22 5.01946671E-06 2.25013974E-05 -1.3110 0.4509 0.3150 0.0449 0.7620 0.2827 0.20043841 KPNA5 karyopherin alpha 5 (importin alpha 6) 0.01323644576 0.027590273438 -1.3126 2.3291 1.8071 2.1123 2.4579 2.7699 2.75071936 EEF1D eukaryotic translation elongation factor 2 1.65970538E-06 8.25650332E-06 -1.3130 0.7333 2.0214 1.4269 0.4754 2.3257 1.25724848 CNOT2 CCR4-NOT transcription complex, subunit 2 3.37035918E-06 1.56668219E-05 -1.3132 1.1819 1.7160 1.0152 1.1347 2.3906 1.686210955 SERINC3 serine incorporator 3 1.67494176E-05 6.71593938E-05 -1.3145 2.5811 1.9234 1.8647 2.6991 1.8733 1.89386124 RPL4 ribosomal protein L4 3.38705257E-07 1.97473595E-06 -1.3155 0.2187 0.1806 0.2379 0.3517 0.2184 0.27076147 RPL23A ribosomal protein L23a 2.13976031E-07 1.31112342E-06 -1.3156 2.9186 44.7004 5.1178 1.4385 26.5326 6.5212283464 GXYLT1 glycosyltransferase 8 domain containing 3 0.00151330798 0.00404138607 -1.3159 1.7089 1.9510 1.6601 1.3000 1.9908 1.8391

solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

90693 CCDC126 coiled-coil domain containing 126 0.01242035808 0.02609760613 -1.3162 1.5751 1.6350 1.6028 1.0535 1.9271 1.4223140609 NEK7 NIMA (never in mitosis gene a)-related kinase 7 9.24715992E-06 3.91573826E-05 -1.3173 1.9703 3.3431 1.6667 2.5662 5.2537 2.860384987 COX14 chromosome 12 open reading frame 62 9.10164088E-07 4.77998205E-06 -1.3177 1.7466 1.7964 1.4662 2.0500 3.4235 1.9250

5291 PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.00289228779 0.007219656072 -1.3184 0.1163 0.1109 0.1651 0.2745 0.0639 0.137885460 ZNF518B zinc finger protein 518B 1.56276488E-06 7.81681904E-06 -1.3186 2.3636 2.8329 1.7142 2.1563 1.6465 1.712810778 ZNF271 zinc finger protein 271 6.27638197E-05 0.000224841455 -1.3188 2.2373 3.0899 1.9084 1.9221 1.1709 1.21285870 RAB6A RAB6A, member RAS oncogene family 1.69721848E-05 6.79184759E-05 -1.3193 1.3946 2.4803 1.4627 1.0971 3.1878 1.6180339290 LINC00667 long intergenic non-protein coding RNA 667 1.96981708E-06 9.62881159E-06 -1.3198 2.4258 1.4450 1.9017 0.9898 2.3040 1.856989887 ZNF628 zinc finger protein 628 0.00078114334 0.002217345217 -1.3204 2.5214 1.9675 1.3811 2.7472 2.3076 2.0217439994 LOC439994 uncharacterized LOC439994 0.01582564582 0.03219038188 -1.3207 3.1748 7.7930 2.1829 1.6954 10.3533 2.33907769 ZNF226 zinc finger protein 226 0.01090304542 0.023292464161 -1.3216 1.9287 2.3040 2.0643 2.0755 2.4036 2.275323064 SETX senataxin 8.18819549E-06 3.50385733E-05 -1.3217 0.8027 1.3809 0.7689 1.0976 2.3059 1.339953616 ADAM22 ADAM metallopeptidase domain 22 0.01743340261 0.035035540318 -1.3221 1.7538 1.8314 1.5792 1.2364 1.7593 1.8109170958 ZNF525 zinc finger protein 525 0.00692255003 0.01564294263 -1.3224 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970200765 TIGD1 tigger transposable element derived 1 0.01538141745 0.031426731485 -1.3225 10.1209 5.2961 2.0168 0.9804 1.8739 1.11877456 WIPF1 WAS/WASL interacting protein family, member 1 1.26399982E-05 5.19473791E-05 -1.3232 2.9599 3.8168 2.2090 2.7621 3.5727 2.21687161 TP73 tumor protein p73 0.02455327467 0.047155500816 -1.3237 0.1198 0.1846 0.3129 0.1173 0.1121 0.3852123803 NTAN1 N-terminal asparagine amidase,N-terminal asparagine amidase 7.2545018E-07 3.90439637E-06 -1.3240 1.4553 1.8301 1.7099 0.9140 1.8695 1.61166429 SRSF4 serine/arginine-rich splicing factor 4 4.94871015E-06 2.2216912E-05 -1.3243 1.2405 2.0228 1.8573 1.2664 3.1529 2.469023401 FRAT2 frequently rearranged in advanced T-cell lymphomas 2 5.56703851E-05 0.000201307991 -1.3245 2.5457 3.2048 1.4169 3.0924 4.6823 1.98716638 SNRPN small nuclear ribonucleoprotein polypeptide N 4.4993342E-06 2.03293359E-05 -1.3247 0.4167 0.2552 0.4934 0.9497 0.4393 0.97447043 TGFB3 transforming growth factor, beta 3 0.02513557293 0.048066686393 -1.3249 2.0899 3.5687 1.7714 1.6831 4.2191 1.45518801 SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 1.23821311E-06 6.32502935E-06 -1.3257 1.3757 0.9478 1.2685 1.2881 1.3034 1.364758533 SNX6 sorting nexin 6 9.96041497E-06 4.18768298E-05 -1.3259 1.8471 4.1606 1.6740 1.7754 4.3624 2.1534150365 MEI1 meiosis defective 1 0.00178613086 0.004679022668 -1.3262 0.9250 0.5792 0.9274 0.6678 0.3759 0.692564747 MFSD1 major facilitator superfamily domain containing 1 0.00028587958 0.000891854472 -1.3270 1.8271 2.2545 1.7455 1.4271 1.7624 1.979010905 MAN1A2 mannosidase, alpha, class 1A, member 2 1.22017788E-06 6.23987974E-06 -1.3273 2.6653 2.9284 2.1221 2.8840 4.2081 3.0594960 CD44 CD44 molecule (Indian blood group) 4.10246801E-05 0.000152318821 -1.3283 0.9624 2.7372 1.0312 1.1406 3.4323 1.1892388650 FAM69A family with sequence similarity 69, member A 0.00018006359 0.000584287339 -1.3343 2.2858 3.4451 1.2131 1.7896 3.1426 1.725623480 SEC61G Sec61 gamma subunit 1.28936223E-05 5.28826635E-05 -1.3345 2.7475 3.2310 1.8346 2.6274 4.8490 3.15349169 SCAF11 SR-related CTD-associated factor 11 1.24185866E-05 5.1129431E-05 -1.3348 1.0326 1.2285 0.6888 1.0506 1.5979 1.1459374900 ZNF568 zinc finger protein 568 0.01012923546 0.021869477755 -1.3355 0.5736 1.4985 2.3659 0.7672 1.4101 1.2457205327 C2orf69 hypothetical protein FLJ38973 3.67512785E-05 0.000137662845 -1.3361 2.0640 3.3344 1.9739 1.7714 3.8283 2.7110

84105 PCBD2 0.01213930161 0.025577642866 -1.3366 2.0073 2.6598 1.5214 1.7612 4.5764 2.421064919 BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 1.29067905E-05 5.29247926E-05 -1.3372 1.4376 3.9420 1.4216 1.6137 6.8877 3.325281689 ISCA1 iron-sulfur cluster assembly 1 1.45411446E-06 7.31541282E-06 -1.3389 0.3321 0.3321 0.3321 0.3970 0.3970 0.39705621 PRNP prion protein 0.00026285467 0.000828082848 -1.3405 1.2222 1.2822 1.2204 1.4178 0.8376 1.2130340591 CA5BP1 carbonic anhydrase VB-like 0.01196000558 0.025243528006 -1.3407 1.6855 2.6125 1.7427 3.0717 4.0642 2.4402100506686 IQCH-AS1 IQCH antisense RNA 1 0.01784254255 0.035760540785 -1.3425 2.7464 0.6732 1.4451 1.1999 0.6614 0.7745284408 ZNF790-AS1 hypothetical protein LOC284408 0.01785419376 0.035774956508 -1.3434 1.3826 1.5823 1.1546 1.7705 2.2322 1.4856152926 PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K 1.24500556E-06 6.35617257E-06 -1.3434 1.5452 3.3598 1.5111 1.4089 4.8557 1.83443673 ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.02151165049 0.042043093133 -1.3438 1.6144 1.4302 2.1099 1.1736 0.9617 1.693089894 TMEM116 transmembrane protein 116 0.01955455504 0.038685668003 -1.3470 5.2395 11.2051 4.1742 5.7885 8.3285 3.983183442 SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 1.41327195E-05 5.74617379E-05 -1.3470 1.8436 4.3091 2.5976 1.5704 3.9918 2.9119466 ATF1 activating transcription factor 1 2.9591308E-05 0.000112582718 -1.3480 2.1505 1.6077 1.8021 2.4654 2.4115 3.031680833 APOL3 apolipoprotein L, 3 0.00219945991 0.005645249538 -1.3482 1.7125 1.5656 1.2635 1.3490 1.8020 0.937184973 SNHG7 small nucleolar RNA host gene 7 (non-protein coding) 4.19746449E-05 0.000155349547 -1.3483 0.6062 3.2028 2.2435 0.5558 3.0877 2.9486120103 SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 0.00535303701 0.012482222089 -1.3493 1.1336 1.4988 0.7091 1.1834 1.4349 1.067351560 RAB6B RAB6B, member RAS oncogene family 0.01769259007 0.035505656874 -1.3501 0.2402 1.1388 1.1453 0.2726 1.9642 0.9208

64398 MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.00206132347 0.005331894454 -1.3511 2.9515 1.9781 1.8181 2.7823 1.9984 2.577080008 TMEM156 transmembrane protein 156 0.00183887692 0.004802052182 -1.3511 3.1693 1.4295 1.8761 2.4935 0.8266 1.806023389 MED13L mediator complex subunit 13-like 5.35631863E-06 2.38756351E-05 -1.3513 4.8048 4.4823 1.2360 5.1596 8.4623 2.4020

23443 SLC35A3 0.01068777026 0.022899500256 -1.3526 0.8415 0.9840 0.9465 0.8149 1.4704 0.971457536 KIAA1328 KIAA1328 0.00138998011 0.003738256777 -1.3534 0.7294 0.5972 0.8185 0.6531 0.1835 0.832980219 COQ10B coenzyme Q10 homolog B (S. cerevisiae) 3.07650076E-06 1.43953449E-05 -1.3538 2.6876 1.7468 1.8554 2.7175 2.7293 2.34126157 RPL27A ribosomal protein L27a 1.95677271E-07 1.21118397E-06 -1.3551 1.5268 1.5182 1.5850 1.7009 3.5996 2.699579685 SAP30L SAP30-like 1.14034525E-06 5.86775229E-06 -1.3553 1.9432 38.0633 3.7796 1.1057 44.7007 4.2825119710 C11orf74 chromosome 11 open reading frame 74 0.01416511579 0.02926229459 -1.3554 1.6852 1.3231 0.7272 1.5607 1.1047 0.7951202018 TAPT1 transmembrane anterior posterior transformation 1 0.00011964015 0.000404153239 -1.3555 2.7449 1.3593 0.1005 1.3032 1.1916 0.19738724 SNX3 sorting nexin 3 3.73048973E-06 1.71869663E-05 -1.3557 2.1868 2.3412 1.6334 2.5598 3.5564 2.301957097 PARP11 poly (ADP-ribose) polymerase family, member 11 0.00045886198 0.00136508078 -1.3573 1.4445 0.8404 1.0296 1.3175 1.0349 1.2108166 AES amino-terminal enhancer of split 4.97188865E-06 2.23100072E-05 -1.3580 0.5805 0.8639 0.7922 0.4278 1.0624 0.771881856 ZNF611 zinc finger protein 611 0.00527823543 0.012336136845 -1.3582 1.0768 0.6764 1.1235 0.9849 0.6581 0.9880222166 C7orf41 chromosome 7 open reading frame 41 0.003713256 0.009027223744 -1.3585 1.0825 1.4689 1.0730 1.3909 2.3898 1.3890440145 MZT1 mitotic spindle organizing protein 1 0.00063454905 0.001831671451 -1.3587 3.0525 4.0633 3.0547 1.4710 2.8450 2.400550809 HP1BP3 heterochromatin protein 1, binding protein 3 5.33098859E-06 2.37754024E-05 -1.3588 0.9170 0.7751 0.5483 0.8932 1.0691 0.773284636 GPR174 G protein-coupled receptor 174 0.00719060548 0.016156082205 -1.3598 1.1398 0.8588 0.9059 0.8536 0.6072 0.593851596 CUTA cutA divalent cation tolerance homolog (E. coli) 7.9412872E-06 3.41258701E-05 -1.3601 1.2563 1.4495 1.2686 1.1765 1.9232 1.223951699 VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 4.12381276E-07 2.34663055E-06 -1.3610 0.7879 8.1548 3.6766 0.3549 2.8355 2.1085100506990 LOC100506990 uncharacterized LOC100506990 0.01580436276 0.032164994025 -1.3619 0.8860 0.8646 1.0432 0.8646 0.4764 0.701379741 C10orf68 chromosome 10 open reading frame 68 0.01336664131 0.027833079195 -1.3629 0.1378 0.0766 0.1256 0.1240 0.0815 0.145964788 LMF1 lipase maturation factor 1 0.00010351585 0.000354733969 -1.3636 0.4708 2.1382 0.9510 0.4143 1.9863 1.07057029 TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 5.45157934E-06 2.42599264E-05 -1.3637 1.2873 0.8500 1.0001 1.1859 0.8582 0.888490637 ZFAND2A zinc finger, AN1-type domain 2A 0.00180395789 0.00471895756 -1.3639 1.8334 2.2697 2.9214 1.6823 2.9253 3.7752151507 MSL3P1 male-specific lethal 3 homolog (Drosophila) pseudogene 1 0.01953438173 0.038662502487 -1.3641 1.3727 1.3957 1.0632 1.2163 1.0870 1.9261389524 GTF2IRD2B GTF2I repeat domain containing 2B 0.00149041944 0.003985503295 -1.3644 0.5614 0.8206 0.6213 0.6160 0.8898 0.713157153 SLC44A2 solute carrier family 44 (choline transporter), member 2 1.12595823E-05 4.67686037E-05 -1.3646 0.5734 0.6861 0.5091 0.5620 0.7643 0.8003401612 SLC25A53 solute carrier family 25, member 53 0.02098357884 0.041156285155 -1.3648 1.9610 2.4426 1.5999 2.4117 3.3384 2.489655176 SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 0.01722505228 0.034658755129 -1.3651 2.0705 0.9740 1.6950 1.7796 1.0956 2.3409221154 MICU2 EF-hand domain family, member A1 3.91545766E-07 2.24707648E-06 -1.3652 0.7732 1.0108 0.8945 0.9588 1.1021 1.17218263 F8A1 coagulation factor VIII-associated 1 1.0390344E-05 4.34743225E-05 -1.3654 6.3756 2.5263 1.9253 4.3216 1.3961 3.744880267 EDEM3 ER degradation enhancer, mannosidase alpha-like 3 4.5218674E-07 2.55010991E-06 -1.3658 2.0274 2.5898 1.9777 2.0709 4.3196 2.99587707 ZNF148 zinc finger protein 148 3.93589053E-07 2.25584779E-06 -1.3669 2.1987 2.7551 1.8905 2.1373 4.4728 2.24387543 ZFX zinc finger protein, X-linked 5.318719E-07 2.94228379E-06 -1.3671 1.1709 0.9788 0.9177 0.8121 0.8558 0.760090594 ZNF439 zinc finger protein 439 0.01702161943 0.034298525609 -1.3674 1.1749 1.0946 0.7877 1.1989 1.2556 0.967664921 CASD1 CAS1 domain containing 1 0.00023424351 0.000743976599 -1.3675 1.8771 1.7467 1.8178 1.9970 2.3039 1.809455773 TBC1D23 TBC1 domain family, member 23 4.97312095E-06 2.23100579E-05 -1.3687 0.9566 1.5253 1.1598 0.7934 1.1607 1.142810933 MORF4L1 mortality factor 4 like 1 9.46136972E-06 3.9934892E-05 -1.3688 1.1507 1.4453 1.4094 2.1034 2.8621 2.18159922 IQSEC1 IQ motif and Sec7 domain 1 1.62369696E-06 8.09721365E-06 -1.3691 0.5226 1.9331 0.9941 0.3204 1.3828 0.80253106 HLA-B major histocompatibility complex, class I, B 1.90584186E-07 1.1828649E-06 -1.3697 0.7972 1.0540 0.8381 0.8373 1.4024 0.90856141 RPL18 ribosomal protein L18 4.43210813E-07 2.50645248E-06 -1.3699 0.3321 0.3321 0.3321 0.3970 0.3970 0.397049855 SCAPER S-phase cyclin A-associated protein in the ER 0.00020356771 0.000653591485 -1.3710 0.5427 0.6148 0.5058 0.4414 0.5503 0.463023476 BRD4 bromodomain containing 4 1.60847873E-06 8.02789494E-06 -1.3712 1.8297 2.5389 1.2871 1.4020 2.9739 1.383923637 RABGAP1 RAB GTPase activating protein 1 4.25840203E-07 2.41869822E-06 -1.3718 1.0101 0.8477 0.9913 0.8000 1.0014 0.983091147 TMEM67 transmembrane protein 67 0.01429793272 0.029496649731 -1.3725 1.1923 1.6685 0.8811 1.1942 1.7198 0.9020138050 HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 2.80504791E-05 0.00010727048 -1.3731 1.6724 2.5172 1.3557 1.3190 2.6135 2.1696161436 EML5 echinoderm microtubule associated protein like 5 0.01567543469 0.031937531128 -1.3732 0.4923 0.5833 0.4140 0.4340 0.7445 0.58715140 PDE3B phosphodiesterase 3B, cGMP-inhibited 0.00025774453 0.000812825009 -1.3736 0.5901 1.3346 0.1789 1.0504 1.3354 1.2794

11014 KDELR2 0.00012854639 0.00043168527 -1.3746 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

3682 ITGAE 1.43144424E-05 5.81367255E-05 -1.3783 1.8919 0.5743 0.9474 0.3429 0.3747 1.186110009 ZBTB33 zinc finger and BTB domain containing 33 1.36418964E-06 6.91441693E-06 -1.3783 1.5602 3.8610 1.1528 1.6917 5.7600 1.95497764 ZNF217 zinc finger protein 217 6.6788514E-06 2.91463991E-05 -1.3784 2.6766 2.2765 2.0169 2.1630 2.0939 1.896310914 PAPOLA poly(A) polymerase alpha 8.3202124E-06 3.55618529E-05 -1.3799 1.9625 2.5630 1.9278 2.0626 4.0074 3.17596049 RNF6 ring finger protein (C3H2C3 type) 6 2.73651964E-06 1.29470966E-05 -1.3816 2.3270 1.2966 1.8142 2.3149 1.4407 2.319927065 NSG1 neuron specific gene family member 1 0.00714159752 0.016064418311 -1.3818 0.5993 0.7071 0.5802 0.3769 0.2309 0.67987782 SLC30A4 solute carrier family 30 (zinc transporter), member 4 0.01434215738 0.029577866788 -1.3832 1.8738 1.1886 1.8119 1.8469 0.8887 2.163284503 ZNF527 zinc finger protein 527 0.0133952619 0.027889496977 -1.3841 2.1456 1.7515 2.1037 1.9776 2.2722 1.897323287 AGTPBP1 ATP/GTP binding protein 1 4.279431E-07 2.42837774E-06 -1.3843 0.3887 0.8405 0.5315 0.5295 0.9614 0.713751082 POLR1D polymerase (RNA) I polypeptide D, 16kDa 8.59436407E-06 3.66307955E-05 -1.3850 2.2265 3.6387 2.1406 1.5749 2.8020 2.617056648 EIF5A2 eukaryotic translation initiation factor 5A2 0.00332409918 0.008170290593 -1.3854 1.6442 2.3870 1.5704 1.4287 2.2068 1.447322990 PCNX pecanex homolog (Drosophila) 0.00014995484 0.000495206014 -1.3856 0.7778 0.7471 0.5247 0.8591 0.9723 0.814555102 ATG2B autophagy related 2B 7.96508398E-07 4.23691454E-06 -1.3857 7.3702 1.1889 5.5850 5.7223 1.7069 8.31595786 PTPRA protein tyrosine phosphatase, receptor type, A 2.07052905E-06 1.00699246E-05 -1.3859 0.6513 1.2467 1.2506 0.7625 0.9079 1.025811104 KATNA1 katanin p60 (ATPase containing) subunit A 1 0.00099567973 0.002767005314 -1.3861 1.1255 0.9986 1.0458 0.9062 1.2304 1.13639559 VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 3.183054E-07 1.86891911E-06 -1.3872 2.0498 4.2830 2.2968 1.9562 6.5634 3.2838203228 C9orf72 chromosome 9 open reading frame 72 0.00753870056 0.016860114633 -1.3873 1.9840 2.3371 1.5744 2.1271 2.0980 1.842680208 SPG11 spastic paraplegia 11 (autosomal recessive) 3.77760692E-07 2.17674026E-06 -1.3879 0.6920 0.7316 0.6658 0.7501 0.8336 0.62085868 RAB5A RAB5A, member RAS oncogene family 2.47141352E-07 1.4878968E-06 -1.3889 6.9983 29.5120 5.5431 6.0947 23.1345 9.636955937 APOM apolipoprotein M 0.0134817518 0.028044008301 -1.3898 0.3270 0.3304 0.3511 0.3944 0.3879 0.4008728229 TMEM191B transmembrane protein 191B 0.0134394203 0.027973830809 -1.3901 1.6187 1.0636 1.2563 1.3216 1.0744 1.2787196294 IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.00491819053 0.011593533578 -1.3902 4.0334 1.4487 0.7668 0.7587 1.1771 0.320555634 KRBOX4 KRAB box domain containing 4 0.00780277848 0.017382634528 -1.3905 1.5790 2.3862 2.5399 1.5720 3.0206 2.8929283635 FAM177A1 chromosome 14 open reading frame 24 1.81693605E-06 8.96060876E-06 -1.3922 1.9791 1.6578 1.3436 2.0594 1.9873 1.95526136 RPL12 ribosomal protein L12 3.50632333E-07 2.03712368E-06 -1.3926 27.5278 2.9450 4.0976 14.9660 2.6105 2.99071506 CTRL chymotrypsin-like 0.01362868863 0.028305798841 -1.3931 0.1480 0.2677 0.2096 0.3166 0.0669 0.172723373 CRTC1 CREB regulated transcription coactivator 1 0.0007908691 0.002242862039 -1.3939 1.4683 1.5060 0.8946 1.0302 1.9402 0.9914202243 CCDC125 coiled-coil domain containing 125 0.00058687725 0.001707551128 -1.3960 0.9472 0.8647 0.8046 0.9733 0.5287 0.728011333 PDAP1 PDGFA associated protein 1 8.42882223E-07 4.46280614E-06 -1.3960 5.2525 4.2588 5.3566 3.0265 5.2638 5.041254149 C21orf91 chromosome 21 open reading frame 91 1.80242871E-06 8.9034813E-06 -1.3965 4.4188 2.9295 2.5501 3.7037 3.7030 3.105279960 PHF17 PHD finger protein 17 2.98802304E-07 1.76528228E-06 -1.3973 2.0277 2.2387 1.0916 2.6360 3.3583 1.998625836 NIPBL Nipped-B homolog (Drosophila) 1.84471319E-06 9.08533676E-06 -1.3983 1.3038 0.7184 0.3103 1.9960 0.8425 0.540779145 CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 3.74999912E-07 2.1649284E-06 -1.3986 2.4445 2.0723 3.0305 1.7540 1.5623 3.82444753 NELL2 NEL-like 2 (chicken) 0.00010289158 0.000352853217 -1.3998 1.2350 1.0484 0.6296 1.5410 1.1978 0.76739852 EPM2AIP1 EPM2A (laforin) interacting protein 1 5.19573052E-07 2.88472768E-06 -1.4007 18.8625 5.4554 1.1519 16.7751 8.1702 2.102227257 LSM1 LSM1, U6 small nuclear RNA associated 2.76101563E-06 1.30562313E-05 -1.4037 3.3323 3.1953 2.0235 2.2866 1.8112 2.13698675 STX16 syntaxin 16 4.05192596E-06 1.84584371E-05 -1.4039 1.6716 1.8516 1.5566 2.0234 3.3521 3.286180862 ZNRD1-AS1 ZNRD1 antisense RNA 1 0.01200900159 0.025337805591 -1.4041 0.9168 0.5308 0.4929 0.6813 0.5685 0.47437710 ZNF154 zinc finger protein 154 0.01160230437 0.024607928656 -1.4042 1.1714 1.9800 1.4433 1.1701 1.5934 1.6756

pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2

solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)

7155 TOP2B topoisomerase (DNA) II beta 180kDa 6.03104654E-06 2.65093294E-05 -1.4043 1.5633 1.2236 1.1826 1.4878 1.5145 1.275655809 TRERF1 transcriptional regulating factor 1 0.00012394409 0.000417688385 -1.4043 1.0581 1.4146 1.3007 1.0361 1.6513 1.4777940 CD28 CD28 molecule 0.00095975318 0.002678571891 -1.4050 2.9008 3.5521 2.3204 3.1581 3.3387 2.223254665 RSBN1 round spermatid basic protein 1 1.17721544E-07 7.66301407E-07 -1.4061 1.8826 2.3511 1.5258 2.2826 3.3874 2.4024221443 OARD1 chromosome 6 open reading frame 130 7.64068747E-06 3.2950352E-05 -1.4073 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970177 AGER advanced glycosylation end product-specific receptor 0.01325781035 0.027625351884 -1.4077 0.3219 0.3361 0.3927 0.3773 0.4228 0.4170100137047 JMJD7 jumonji domain containing 7 0.00872150713 0.019167008909 -1.4096 0.2918 0.3001 0.2881 0.3619 0.2411 0.34726009 RHEB Ras homolog enriched in brain 2.38106578E-07 1.44014677E-06 -1.4107 1.2564 2.5440 1.3569 1.2528 3.3057 1.837755297 CCDC91 Q05D28,Q7Z6B0,coiled-coil domain containing 91 0.00031098804 0.000963277405 -1.4109 0.1669 0.2247 0.2033 0.2626 0.1752 0.1454

6727 SRP14 2.44945714E-06 1.17286375E-05 -1.4110 1.1542 1.3322 3.9991 0.5878 1.3583 2.9752116987 AGAP1 centaurin, gamma 2 0.01939130326 0.038408443704 -1.4115 1.2711 1.4564 0.8341 1.1764 0.3851 0.52392060 EPS15 epidermal growth factor receptor pathway substrate 15 2.79182989E-06 1.31848839E-05 -1.4122 0.4314 1.1763 0.7482 0.4335 1.7112 0.92124747 NEFL neurofilament, light polypeptide 0.01176501811 0.024909665219 -1.4131 2.3736 1.8678 1.6065 1.5431 1.2986 1.229523394 ADNP activity-dependent neuroprotector homeobox 1.11584762E-07 7.30518369E-07 -1.4136 1.9150 3.3948 2.1146 2.0322 3.3749 3.17119877 ZC3H11A zinc finger CCCH-type containing 11A 5.3573831E-06 2.38756351E-05 -1.4139 1.1536 1.0966 0.8338 0.9445 1.1697 0.768691746 YTHDC1 YTH domain containing 1 6.55658317E-07 3.5591767E-06 -1.4153 1.1096 1.5060 0.9575 1.1164 2.3998 1.2788

100288615 WHAMMP1 0.00304837723 0.007574102347 -1.4156 0.5407 1.5050 1.0225 0.7888 0.9512 0.7503339287 MSL1 male-specific lethal 1 homolog (Drosophila) 4.65387446E-07 2.61728514E-06 -1.4162 0.8750 0.6289 0.7432 0.8721 0.8023 1.0953474344 GIMAP6 GTPase, IMAP family member 6 0.00150192239 0.004012739564 -1.4162 3.5401 3.1967 2.5661 3.1184 3.8855 2.3386283981 LINC00685 chromosome X and Y open reading frame 10 0.01214853613 0.025594148766 -1.4165 4.2692 1.4720 1.5074 2.9872 0.4788 0.7236642852 LOC642852 uncharacterized LOC642852 0.00640172434 0.014612405646 -1.4169 0.6188 3.0750 0.2201 0.2870 16.7502 0.148510550 ARL6IP5 ADP-ribosylation-like factor 6 interacting protein 5 8.39268029E-05 0.000293663451 -1.4171 1.8775 2.0644 2.1440 1.6889 2.4834 2.328023091 ZC3H13 zinc finger CCCH-type containing 13 9.14510268E-08 6.11637321E-07 -1.4194 10.3616 0.9726 0.6143 5.6478 0.9595 0.341051727 CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 4.20834522E-06 1.91217926E-05 -1.4195 2.1224 3.4342 1.3992 2.3994 4.5420 1.836329929 ALG6 ALG6, alpha-1,3-glucosyltransferase 0.00077541345 0.00220279144 -1.4203 1.2476 1.1412 0.9842 1.0395 1.3830 1.07775411 PNN pinin, desmosome associated protein 3.99687045E-06 1.82349106E-05 -1.4208 2.0900 2.8393 1.6864 2.3265 4.2796 2.898027125 AFF4 AF4/FMR2 family, member 4 1.22776885E-07 7.94679154E-07 -1.4214 1.6323 2.0685 1.5842 1.4418 1.7820 1.7895388165 UBE2Q2P1 ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 1 0.01762534768 0.035386260053 -1.4217 0.3321 0.3321 0.3321 0.3970 0.3970 0.397055810 FOXJ2 forkhead box J2 1.81046949E-06 8.9311281E-06 -1.4223 2.5350 2.1035 2.1227 1.7017 2.3082 2.6034

260425 MAGI3 0.01215200903 0.025595911839 -1.4229 0.5566 0.7294 0.7382 0.6604 1.2542 1.029255967 NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 7.96992461E-07 4.2382556E-06 -1.4235 2.6615 3.0302 1.8489 2.6802 4.8965 2.180611201 POLI polymerase (DNA directed) iota 0.00359183348 0.0087588391 -1.4247 0.8217 1.4754 1.3039 0.6621 0.8687 1.103658515 SELK selenoprotein K 4.82136188E-05 0.000176332915 -1.4251 1.6805 2.1302 1.8150 1.6506 3.4016 2.1410375056 MIA3 melanoma inhibitory activity family, member 3 8.35340855E-08 5.65099893E-07 -1.4271 1.4313 2.7281 1.4760 1.4746 2.9357 1.92168667 EIF3H eukaryotic translation initiation factor 3, subunit H 2.52254658E-06 1.20376002E-05 -1.4282 1.2640 1.5062 0.8483 1.8446 2.6516 1.11425771 PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.52359845E-07 9.66974328E-07 -1.4282 1.9240 2.6730 1.5928 1.5771 2.6410 2.45573189 HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 3.08522036E-06 1.44324492E-05 -1.4285 1.9398 1.9581 1.5858 2.0380 1.3456 1.658451754 TMEM8B transmembrane protein 8B 0.01234173112 0.025962250867 -1.4289 0.9274 1.3057 0.9333 0.4864 1.3327 0.697583464 APH1B anterior pharynx defective 1 homolog B (C. elegans) 0.00032663133 0.001007292443 -1.4311 2.2354 2.1167 2.2766 1.6273 2.0431 2.095822807 IKZF2 IKAROS family zinc finger 2 (Helios) 0.00274216644 0.006880646147 -1.4314 1.2836 1.3563 1.1640 1.0555 1.0802 0.91286137 RPL13 ribosomal protein L13 5.91909863E-07 3.24688592E-06 -1.4317 2.8456 2.5872 1.5028 1.7519 1.7375 1.045210982 MAPRE2 microtubule-associated protein, RP/EB family, member 2 3.76571152E-06 1.73186713E-05 -1.4317 2.6695 2.9033 1.9281 2.4189 2.9395 2.198980303 EFHD1 EF-hand domain family, member D1 0.01365950659 0.028355658316 -1.4322 0.8276 1.6827 0.7451 0.7017 1.6873 0.74317597 ZBTB25 zinc finger and BTB domain containing 25 6.41444158E-05 0.000229228783 -1.4338 3.8531 4.7897 2.7006 2.9930 4.4547 2.482026234 FBXL5 F-box and leucine-rich repeat protein 5 2.22529475E-05 8.68444801E-05 -1.4347 0.8654 2.2381 1.1177 0.6015 3.2740 1.22693931 LCAT lecithin-cholesterol acyltransferase 0.01108481846 0.02362830179 -1.4352 0.0172 0.1117 0.1444 0.1248 0.0892 0.1881386627 SAP30L-AS1 SAP30L antisense RNA 1 (head to head) 0.01071173664 0.022945469163 -1.4354 3.0390 4.2403 1.7376 0.8855 2.7636 1.1004919 CD247 CD247 molecule 4.14461096E-05 0.000153642385 -1.4364 1.6135 1.5925 2.0834 2.0718 2.3571 2.625692241 RCSD1 RCSD domain containing 1 4.11936802E-06 1.87563151E-05 -1.4366 1.9498 2.7407 2.4184 1.7515 3.0869 2.1442768211 RELL1 RELT-like 1 9.28587992E-05 0.000321104462 -1.4378 1.5301 2.6314 1.5906 1.4040 2.8701 2.225292912 UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 1.28551415E-06 6.54105113E-06 -1.4385 1.2001 1.4674 0.9141 1.0057 1.4778 1.1821340554 ZC3H12B zinc finger CCCH-type containing 12B 0.01045298957 0.022459669027 -1.4396 0.2353 0.1171 0.2121 0.2942 0.8768 0.146623013 SPEN spen family transcriptional repressor 2.47666224E-06 1.18495869E-05 -1.4397 1.2500 1.5057 1.1093 1.4894 0.8251 1.34028867 SYNJ1 synaptojanin 1 0.00012698807 0.000427005977 -1.4397 1.3678 0.9888 0.9576 0.8589 0.5278 0.8436219790 RTKN2 pleckstrin homology domain containing, family K member 1 0.00136664173 0.003684166071 -1.4398 0.8650 1.1259 0.8230 0.8093 0.8459 0.8068222194 RSBN1L round spermatid basic protein 1-like 2.28425656E-05 8.89555325E-05 -1.4400 1.4790 2.7882 1.4164 2.5838 4.5910 2.37745523 PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.00936171946 0.02041257016 -1.4419 0.4362 0.8117 0.4947 0.5242 0.6902 0.690554065 SMIM11 small integral membrane protein 11 9.13652699E-05 0.000316358956 -1.4420 2.0988 1.3998 2.1936 1.9018 1.1068 1.8174389203 SMIM20 small integral membrane protein 20 6.16815493E-05 0.000221293004 -1.4425 1.6469 2.4681 1.9008 1.4964 2.0060 1.79733188 HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 0.0086418526 0.019008538668 -1.4425 9.7044 1.6468 4.5267 4.7389 1.1100 4.1002

55814 BDP1 1.40572555E-07 8.98719991E-07 -1.4427 0.7794 0.5740 0.6867 0.9403 1.1530 0.8503962 CD48 CD48 molecule 5.6894794E-05 0.000205329188 -1.4430 3.7758 1.4080 2.5594 3.0857 2.5817 3.0599596 BCL2 B-cell CLL/lymphoma 2 1.89915625E-05 7.51925958E-05 -1.4431 3.4775 2.1026 1.4319 4.9083 3.8194 3.74918773 SNAP23 synaptosomal-associated protein, 23kDa 7.08583468E-08 4.88206528E-07 -1.4441 2.1097 2.2673 2.0419 2.0975 2.4174 2.07509443 MED7 mediator complex subunit 7 0.00106706751 0.002946125348 -1.4448 2.5965 2.5379 2.0134 2.7010 4.3586 2.9939728730 LOC728730 uncharacterized LOC728730 0.0136505724 0.028340331651 -1.4455 1.2708 1.8930 2.0033 0.7347 0.9190 1.1100132299 OCIAD2 OCIA domain containing 2 8.78920436E-07 4.63214139E-06 -1.4457 2.3196 1.5304 2.4565 1.4466 1.3800 1.79604698 NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 7.70411891E-08 5.2604507E-07 -1.4466 2.5216 3.2411 1.7092 3.0536 4.0760 2.3555113510 HELQ helicase, POLQ-like 0.00056455704 0.001648383855 -1.4469 2.5279 3.9633 3.2139 1.3005 1.6241 2.3009400410 ST20 suppressor of tumorigenicity 20 0.01505571308 0.030861340514 -1.4481 1.0808 0.6719 1.0909 0.7456 0.5821 1.11712959 GTF2B general transcription factor IIB 6.00481146E-07 3.29192664E-06 -1.4485 1.9074 1.7415 1.7238 2.3278 2.6444 1.92807507 XPA xeroderma pigmentosum, complementation group A 8.51646819E-05 0.000297539019 -1.4491 2.1493 2.7243 2.2927 1.8288 3.1222 2.428456965 PARP6 poly (ADP-ribose) polymerase family, member 6 2.76502818E-05 0.00010589519 -1.4502 0.6229 1.1006 0.9683 0.4337 0.9869 0.85915152 PDE9A phosphodiesterase 9A 0.00169525725 0.00446915892 -1.4504 0.8243 1.3655 0.7605 0.7920 0.8013 0.6824145553 MDP1 magnesium-dependent phosphatase 1 0.00878699563 0.019290638499 -1.4506 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970146857 SLFN13 schlafen family member 13 5.07320955E-05 0.000184803997 -1.4510 0.7883 1.0399 0.8300 0.8565 0.5275 0.5031100129482 ZNF37BP zinc finger protein 37B, pseudogene 8.25750363E-05 0.000289321393 -1.4528 1.8410 3.6027 1.8323 2.2407 4.6331 2.3491

659 BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 4.55742665E-07 2.56739261E-06 -1.4530 2.0084 2.8628 1.5763 2.5471 4.1862 3.294526224 FBXL3 F-box and leucine-rich repeat protein 3 1.36679558E-05 5.57955516E-05 -1.4534 2.2747 3.4269 1.7002 1.8648 3.2482 2.50286674 SPAG1 sperm associated antigen 1 0.00251660453 0.006377725108 -1.4538 0.9002 1.2761 1.6202 0.5505 0.7659 1.15509318 COPS2 COP9 signalosome subunit 2 3.99189875E-06 1.82167767E-05 -1.4539 5.9313 19.7413 1.6995 3.2344 11.9247 1.348354893 MTMR10 myotubularin related protein 10 1.98998155E-06 9.71957841E-06 -1.4543 0.5444 0.8627 0.4087 0.6358 1.0960 0.591626057 ANKRD17 ankyrin repeat domain 17 2.95997907E-05 0.000112582718 -1.4567 1.4700 1.2422 0.8220 1.5964 1.8980 1.327954331 GNG2 guanine nucleotide binding protein (G protein), gamma 2 3.01896733E-06 1.41587708E-05 -1.4570 1.9934 1.8922 1.5766 1.7181 1.7326 1.371057489 ODF2L outer dense fiber of sperm tails 2-like 0.00058557988 0.001704047715 -1.4584 1.9338 1.9926 1.8590 1.9496 2.1733 1.964690639 COX19 COX19 cytochrome c oxidase assembly homolog (S. cerevisiae) 2.66275001E-06 1.26244889E-05 -1.4587 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

9255 AIMP1 1.20592352E-06 6.17389595E-06 -1.4592 1.8046 1.3759 1.8652 0.8841 1.3557 0.987823126 POGZ pogo transposable element with ZNF domain 9.18660504E-07 4.81934101E-06 -1.4596 0.9190 0.7896 0.6505 0.9431 0.7240 0.5410

6641 SNTB1 0.00055794098 0.001630369043 -1.4599 2.0837 2.1249 1.0369 1.7696 1.6205 1.66259659 PDE4DIP phosphodiesterase 4D interacting protein 0.00035717462 0.001090077608 -1.4599 0.4991 0.5835 0.6521 0.5970 0.6369 0.69377172 TPMT thiopurine S-methyltransferase 0.00034786911 0.001064879281 -1.4602 1.6517 2.0499 0.7991 0.8131 1.1042 0.682723518 R3HDM1 R3H domain containing 1 4.24947819E-08 3.09471764E-07 -1.4604 0.9603 2.2967 0.8946 0.4484 5.4193 0.784423275 POFUT2 protein O-fucosyltransferase 2 2.82605793E-05 0.0001079384 -1.4623 4.6235 2.6715 0.7840 5.4027 1.4107 0.38282035 EPB41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) 8.30198704E-06 3.55005633E-05 -1.4638 0.9154 1.1021 0.9862 0.7716 1.0040 0.857984333 PCGF5 polycomb group ring finger 5 9.30879833E-06 3.93636573E-05 -1.4642 1.2764 2.6629 2.0165 1.3161 2.7927 2.40722551 GABPA GA binding protein transcription factor, alpha subunit 60kDa 1.17313681E-06 6.02122355E-06 -1.4645 3.6080 3.7651 2.2796 3.5201 5.2095 2.99295616 PRKY protein kinase, Y-linked, pseudogene 0.00047588747 0.001411364357 -1.4654 2.0020 5.6285 1.6449 1.4528 6.9735 2.88168816 DCAF5 DDB1 and CUL4 associated factor 5 7.89470285E-08 5.37651921E-07 -1.4656 1.7141 3.0808 1.4390 1.4747 3.5490 2.153492283 ZNF461 zinc finger protein 461 0.00913351453 0.01997457541 -1.4658 2.2664 1.7121 1.8299 2.3807 2.2434 2.3827114932 MRFAP1L1 Morf4 family associated protein 1-like 1 7.29092012E-07 3.92053244E-06 -1.4672 2.7237 2.6365 2.3259 2.7880 3.6624 2.7011100506826 MYLK-AS1 MYLK antisense RNA 1 0.01643305118 0.033266642057 -1.4684 3.0134 2.8504 2.3352 1.7579 3.1156 2.406479699 ZYG11B zyg-11 family member B, cell cycle regulator 2.03213037E-07 1.25315849E-06 -1.4686 1.2547 1.4857 1.3710 1.1809 1.4899 1.22091140 CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 0.00028138779 0.00087934287 -1.4690 0.6964 1.3347 1.3611 0.4790 1.3855 1.1234221016 CCDC7 coiled-coil domain containing 7 0.00807613835 0.017923867364 -1.4699 1.6452 1.3318 1.0935 2.0350 2.2017 1.2769

727896 LOC727896 0.011241328 0.023920058845 -1.4700 0.1876 0.3722 0.4665 0.2954 0.4063 0.294584270 C9orf89 chromosome 9 open reading frame 89 3.56064217E-05 0.000133538698 -1.4706 1.5669 1.8064 2.0015 1.2243 1.9584 2.9762

115426 UHRF2 2.10589633E-06 1.0223187E-05 -1.4715 0.7905 1.2363 0.7938 0.9806 1.5278 0.980851441 YTHDF2 YTH domain family, member 2 6.3422981E-07 3.45105631E-06 -1.4724 1.6349 2.1649 1.8295 1.2948 2.6222 2.2166121274 ZNF641 zinc finger protein 641 5.79100365E-05 0.000208745746 -1.4727 2.4450 1.8303 1.5484 2.0692 1.9300 1.449292285 ZNF585B zinc finger protein 585B 0.00202147881 0.005236985792 -1.4753 1.7447 2.1781 1.6827 2.0693 2.7951 1.6769100216546 LINC01004 long intergenic non-protein coding RNA 1004 0.00380461221 0.009218654585 -1.4755 0.6680 0.2808 0.3458 0.5981 0.2720 0.2668146542 ZNF688 zinc finger protein 688 0.00034240552 0.001050795052 -1.4760 1.7360 2.3017 1.9283 1.9134 1.9131 2.583010893 MMP24 matrix metallopeptidase 24 (membrane-inserted) 0.00277623674 0.006958490764 -1.4760 0.3312 0.6286 0.5980 0.2281 0.1820 0.59537046 TGFBR1 transforming growth factor, beta receptor 1 3.29567677E-07 1.92699539E-06 -1.4764 1.7336 2.2568 1.4532 1.4489 1.7290 1.299851466 EVL Enah/Vasp-like 0.00017135488 0.000558607745 -1.4773 1.5447 1.4808 1.2673 1.2876 1.4118 1.231856242 ZNF253 zinc finger protein 253 0.0051971195 0.012174585571 -1.4778 1.5915 1.5308 1.4538 1.9465 3.5587 2.25196711 SPTBN1 spectrin, beta, non-erythrocytic 1 1.13912978E-06 5.8631491E-06 -1.4778 0.7189 1.3722 1.1301 0.8331 1.3266 1.0864399844 LINC01002 long intergenic non-protein coding RNA 1002 0.0015168181 0.004050168096 -1.4780 0.0038 0.0988 0.1230 0.1453 0.0408 0.16018635 RNASET2 ribonuclease T2 1.63938827E-06 8.17100447E-06 -1.4794 1.9452 1.6998 2.0299 1.2959 1.6296 1.7118148266 ZNF569 zinc finger protein 569 0.00570468981 0.013199454495 -1.4799 0.8593 2.5753 1.1973 0.8351 1.5831 0.90789140 ATG12 autophagy related 12 2.8617183E-08 2.16608603E-07 -1.4811 5.6261 5.5526 2.4993 1.8714 4.8349 2.59315869 RAB5B RAB5B, member RAS oncogene family 4.78768721E-07 2.68180934E-06 -1.4812 1.8585 1.8379 2.1064 2.0640 2.2229 2.746264839 FBXL17 F-box and leucine-rich repeat protein 17 2.14520858E-05 8.40209067E-05 -1.4828 1.6046 1.0893 1.3905 1.6813 1.2714 2.276984190 METTL25 methyltransferase like 25 0.007977801 0.017728664546 -1.4836 0.3321 0.3321 0.3321 0.3970 0.3970 0.397084456 L3MBTL3 l(3)mbt-like 3 (Drosophila) 0.0007655494 0.002178156134 -1.4846 1.2988 1.4027 1.5897 1.3449 2.0444 1.671892104 TTC30A tetratricopeptide repeat domain 30A 0.0136741019 0.028373062674 -1.4849 1.8517 1.5393 1.2211 2.8747 1.4388 1.7093729799 SEC14L1P1 SEC14-like 1 pseudogene 1 0.00780262955 0.017382634528 -1.4859 0.0783 0.0736 0.1756 0.1469 0.0143 0.1373115992 RNF166 ring finger protein 166 2.68063344E-06 1.27023688E-05 -1.4859 2.1599 7.5906 5.7956 1.0397 2.5163 6.3128122622 ADSSL1 adenylosuccinate synthase like 1 0.00932308028 0.020337038533 -1.4862 0.4928 0.5299 0.7854 0.4589 0.4825 0.8980116828 N4BP2L2-IT2 N4BPL2 intronic transcript 2 (non-protein coding) 0.00762214966 0.017021745128 -1.4866 0.0681 0.0819 0.0744 0.1039 0.1649 0.0880390595 UBAP1L ubiquitin associated protein 1-like 0.01132940102 0.024082226092 -1.4875 0.0845 0.0501 0.2042 0.1248 0.1857 0.15833953 LEPR leptin receptor 0.01471720755 0.030242107102 -1.4892 0.2735 0.2602 0.3987 0.4228 0.3119 0.390157496 MKL2 MKL/myocardin-like 2 8.98189099E-06 3.81047393E-05 -1.4893 0.6968 0.9442 0.8942 0.6522 0.8236 0.7839132660 LIN54 lin-54 homolog (C. elegans) 1.01450514E-07 6.70417285E-07 -1.4894 2.4753 2.8339 1.6161 2.3834 3.3303 2.29833020 H3F3A H3 histone, family 3A 0.00175940887 0.004617626962 -1.4895 3.1103 3.2954 1.3317 4.3327 3.6602 2.7885

signal recognition particle 14kDa (homologous Alu RNA binding protein)

WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 1

membrane associated guanylate kinase, WW and PDZ domain containing 3

B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)

similar to cysteine and histidine-rich domain (CHORD)-containing, zinc binding protein 1

ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase

441024 MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 0.0062081721 0.014216588578 -1.4900 0.4460 0.7227 0.5114 0.5113 0.5600 0.513051326 ARL17A ADP-ribosylation factor-like 17A 7.94656678E-05 0.000279445089 -1.4902 0.6213 0.6760 0.6791 0.6462 0.7496 0.79841656 DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 1.72298572E-06 8.54107301E-06 -1.4903 0.9842 0.9331 0.9164 1.4208 1.4837 2.1057168537 GIMAP7 GTPase, IMAP family member 7 0.00176861158 0.004639114395 -1.4912 2.4326 3.4352 2.4400 2.7821 3.8108 2.9559113230 LOC113230 uncharacterized LOC113230 0.02172260239 0.042391903338 -1.4925 1.7854 3.4142 2.3492 0.6201 2.6380 3.427229767 TMOD2 tropomodulin 2 (neuronal) 0.00143327208 0.003846760799 -1.4927 0.5335 1.4922 1.8554 0.1676 9.1462 1.015555545 MSX2P1 msh homeobox 2 pseudogene 1 0.00666351017 0.015126805543 -1.4928 2.0311 1.8959 1.9136 1.7605 2.3513 1.643210569 SLU7 SLU7 splicing factor homolog (S. cerevisiae) 2.18235229E-08 1.71265934E-07 -1.4930 2.5860 1.9114 1.4853 2.0759 1.7681 1.69742113 ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.64402964E-07 1.58106339E-06 -1.4932 1.6649 1.9225 0.9476 1.9083 2.2890 1.6790100216545 KMT2E-AS1 KMT2E antisense RNA 1 (head to head) 0.00013264486 0.000443330325 -1.4937 0.0371 0.3464 0.1310 0.0512 0.4247 0.180955145 THAP1 THAP domain containing, apoptosis associated protein 1 4.60509712E-06 2.07712502E-05 -1.4943 2.7248 2.8209 1.6664 2.9789 3.8257 2.456810289 EIF1B eukaryotic translation initiation factor 1B 7.1578111E-05 0.000253513325 -1.4953 5.7347 2.0851 0.1238 3.2092 1.3018 0.124864786 TBC1D15 TBC1 domain family, member 15 9.28146801E-06 3.92571721E-05 -1.4981 2.6182 2.7698 2.4860 2.6550 3.5061 2.9415284161 GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 0.00775014209 0.017282230441 -1.4985 1.2725 1.3396 1.4474 1.1925 1.4171 2.1019389170 LEKR1 leucine, glutamate and lysine rich 1 0.01006584254 0.02175831952 -1.4990 1.1142 1.5787 1.7831 1.1410 1.2809 1.65803726 JUNB jun B proto-oncogene 5.40812363E-05 0.000196104852 -1.4991 2.5017 3.1478 2.1343 2.3019 4.3755 3.5667134553 C5orf24 chromosome 5 open reading frame 24 7.29114677E-08 5.00465191E-07 -1.4992 2.0926 2.9217 1.4648 1.6991 3.1926 1.784351379 CRLF3 cytokine receptor-like factor 3 1.66702703E-06 8.28615832E-06 -1.4994 1.5950 3.3405 1.8688 1.8957 5.8756 2.59429134 CCNE2 cyclin E2 0.01177576393 0.024929528284 -1.5009 1.5074 3.8552 2.6436 1.5365 4.0648 4.08227328 UBE2H ubiquitin-conjugating enzyme E2H 9.14426643E-07 4.79988613E-06 -1.5011 1.3738 1.6990 1.4961 1.0061 1.9444 1.8558100129361 LOC100129361 chromosome X open reading frame 69-like 1.39332832E-05 5.67139565E-05 -1.5015 1.5333 1.8643 1.7863 1.6799 0.7747 0.88339617 MTRF1 mitochondrial translational release factor 1 0.00654433385 0.014893270418 -1.5037 1.3436 1.0748 0.7317 1.6660 1.7296 1.1166989 SEPT7 septin 7 1.20064912E-06 6.15206415E-06 -1.5042 1.6743 2.9935 0.6462 1.3758 4.0524 1.242664282 PAPD5 PAP associated domain containing 5 3.18019704E-05 0.000120183165 -1.5043 1.9912 1.5681 2.1929 1.8998 2.3835 2.4652102 ADAM10 ADAM metallopeptidase domain 10 2.14785667E-06 1.04044637E-05 -1.5046 1.1761 1.5464 1.0198 1.1198 1.6516 1.3690606724 LOC606724 coronin, actin binding protein, 1A pseudogene 6.8065048E-06 2.96256445E-05 -1.5066 0.3359 0.3758 0.4352 0.4240 0.1989 0.3777162967 ZNF320 zinc finger protein 320 0.00824308087 0.018245617654 -1.5087 0.5701 0.6687 0.6430 0.5130 0.7272 0.66799208 LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 1.33360764E-06 6.76879964E-06 -1.5094 1.1713 1.4279 1.1854 1.2281 1.4368 1.794511276 SYNRG synergin, gamma 3.30668308E-07 1.93281232E-06 -1.5094 0.8042 1.8215 0.5189 0.7695 2.1873 0.715010390 CEPT1 choline/ethanolamine phosphotransferase 1 2.29104133E-06 1.10353992E-05 -1.5100 1.6686 2.5833 1.0580 0.7747 1.0877 0.554823200 ATP11B ATPase, class VI, type 11B 2.26479592E-07 1.37620057E-06 -1.5108 0.7718 1.0203 0.4894 0.8195 1.3916 0.75406201 RPS7 ribosomal protein S7 9.96110861E-09 8.50113856E-08 -1.5109 0.9758 1.8146 1.6013 0.8561 3.2878 1.601123683 PRKD3 protein kinase D3 8.24516581E-08 5.58811831E-07 -1.5114 0.4650 0.6853 0.3615 0.4504 0.3318 0.288656160 NDNL2 necdin-like 2 5.70209019E-06 2.52456002E-05 -1.5117 2.6039 3.7396 1.7028 2.3972 4.4851 2.428381550 TDRD3 tudor domain containing 3 1.01528511E-06 5.2807542E-06 -1.5132 1.2332 1.2209 0.8106 1.1674 1.7664 1.18658491 MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.00524724607 0.012269987236 -1.5137 0.2015 0.2436 0.2261 0.2804 0.3143 0.270457649 PHF12 PHD finger protein 12 1.49083403E-07 9.47826005E-07 -1.5140 1.8159 2.4173 1.3182 1.5552 3.1289 1.80587110 TMF1 TATA element modulatory factor 1 1.62765365E-08 1.31828402E-07 -1.5142 2.2526 1.8194 1.5718 2.5094 2.9702 1.9805409 ARRB2 arrestin, beta 2 1.10685864E-06 5.71152814E-06 -1.5142 1.6250 2.1180 2.6556 1.2640 2.6253 3.9637728262 FAM157A family with sequence similarity 157, member A 0.00332325087 0.008169304434 -1.5151 0.1133 0.2472 0.2394 0.2661 0.1494 0.219710668 CGRRF1 cell growth regulator with ring finger domain 1 0.00281695787 0.007049918388 -1.5166 1.9192 2.6174 1.5590 1.6787 3.0040 1.7238493753 COA5 hypothetical protein MGC52110 5.80975135E-05 0.00020938023 -1.5170 1.5830 8.5496 4.6867 0.4429 19.1704 2.493157563 KLHL8 kelch-like family member 8 1.21307519E-06 6.20703162E-06 -1.5176 1.8405 3.3516 1.9919 1.5814 3.4069 2.480651141 INSIG2 insulin induced gene 2 3.82456488E-05 0.000142879676 -1.5178 1.1112 1.3901 1.1762 1.0784 1.5903 1.71019209 LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 3.24248345E-07 1.89832289E-06 -1.5183 1.8777 2.4576 1.5992 1.6961 2.2237 2.2779241 ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00177154769 0.004645482124 -1.5191 1.7364 1.0171 1.5596 1.2944 0.6987 1.0633145482 PTGR2 prostaglandin reductase 2 0.01852646185 0.03695180776 -1.5202 0.0608 0.5975 0.1566 0.1842 1.2407 0.14296458 SH3GL1P1 SH3-domain GRB2-like 1 pseudogene 1 0.01066562714 0.022857417213 -1.5202 0.0493 0.0205 0.1658 0.2723 0.1297 0.158910094 ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 6.67762755E-07 3.61736171E-06 -1.5213 1.6665 1.3544 1.5906 1.9070 1.9229 2.297484142 FAM175A family with sequence similarity 175, member A 7.5829139E-06 3.273984E-05 -1.5220 2.0524 2.8729 1.6347 1.4894 2.7779 1.49989317 PTER phosphotriesterase related 8.42004087E-06 3.59297026E-05 -1.5222 1.4009 3.3783 1.6538 0.9405 3.4454 1.5658

56261 GPCPD1 3.35981833E-05 0.000126422159 -1.5227 1.2150 1.5755 0.8302 1.5718 2.0238 1.40202054 STX2 syntaxin 2 6.9244648E-05 0.000245916075 -1.5228 1.8836 5.6647 1.7278 1.2807 3.4194 1.4441493754 LOC493754 RAB guanine nucleotide exchange factor (GEF) 1 pseudogene 7.57089861E-05 0.000267211627 -1.5238 1.5927 1.8604 1.8775 1.0791 1.4444 2.114996459 FNIP1 folliculin interacting protein 1 2.56681904E-06 1.22192107E-05 -1.5261 0.3321 0.3321 0.3321 0.3970 0.3970 0.397079665 DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 1.99985946E-07 1.23450784E-06 -1.5264 0.6555 0.5940 0.6936 0.7624 1.1419 0.68688464 SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.00027129445 0.000851002943 -1.5272 1.1603 1.6911 1.0276 1.0077 1.8405 1.4542150967 PKI55 DKFZp434H1419 0.00188809495 0.004919331368 -1.5278 0.2622 0.5013 1.1399 0.2352 0.8868 0.4960

4718 NDUFC2 3.25964371E-07 1.90775816E-06 -1.5282 0.3321 0.3321 0.3321 0.3970 0.3970 0.397064130 LIN7B lin-7 homolog B (C. elegans) 0.00751780453 0.016817498094 -1.5282 1.2637 2.0861 2.3288 0.6956 2.1702 2.01909866 TRIM66 tripartite motif containing 66 0.00439393414 0.010494897333 -1.5287 0.1141 0.0235 0.2632 0.2319 0.0170 0.17304017 LOXL2 lysyl oxidase-like 2 0.0052144668 0.012210526382 -1.5291 0.1872 0.8401 0.6867 0.2186 0.2232 0.3313139231 FAM199X family with sequence similarity 199, X-linked 2.40962561E-08 1.86246528E-07 -1.5304 0.9125 0.6527 1.4178 0.7403 0.4435 1.77048725 URI1 URI1, prefoldin-like chaperone 4.43759806E-07 2.50733129E-06 -1.5304 0.9781 0.6988 0.4669 0.7711 0.7384 0.46186222 RPS18 ribosomal protein S18 7.94019237E-07 4.22676471E-06 -1.5305 0.7280 1.0332 0.9479 0.3994 1.4403 0.748257595 PDZD4 PDZ domain containing 4 0.01049586271 0.022533239733 -1.5308 0.8340 0.4003 1.1090 0.6588 0.3186 0.831256655 POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 5.72109276E-08 4.01597414E-07 -1.5311 1.1666 2.7354 1.7161 0.7625 3.5181 1.5758

8925 HERC1 2.57784788E-06 1.2263066E-05 -1.5321 2.6488 2.7189 2.3413 2.5310 3.6693 2.96489528 TMEM59 transmembrane protein 59 2.4463279E-07 1.47522453E-06 -1.5324 1.7716 2.4786 1.6277 1.0839 3.1962 1.774584071 ARMC2 armadillo repeat containing 2 0.00608771209 0.013968940768 -1.5327 1.9571 2.3367 1.3451 1.3412 2.3630 1.591711118 BTN3A2 butyrophilin, subfamily 3, member A2 2.17919992E-06 1.05367401E-05 -1.5336 2.6359 1.6439 1.8344 2.0983 1.9358 1.55083653 IPW imprinted in Prader-Willi syndrome (non-protein coding) 0.00030756049 0.000953744181 -1.5339 0.1512 0.2107 0.2617 0.2828 0.4768 0.230597 ACYP1 acylphosphatase 1, erythrocyte (common) type 0.00079880118 0.002264302692 -1.5341 2.6694 1.4026 2.1592 2.0777 2.0345 1.838984458 LCOR ligand dependent nuclear receptor corepressor 6.18309972E-06 2.7131988E-05 -1.5347 1.9173 3.7925 1.7103 1.6994 3.6100 1.983210427 SEC24B SEC24 family member B 2.46959461E-08 1.9039845E-07 -1.5376 0.3321 0.3321 0.3321 0.3579 0.3842 0.37993964 LGALS8 lectin, galactoside-binding, soluble, 8 8.88342943E-08 5.96318966E-07 -1.5377 0.5514 0.4255 0.4306 0.3933 0.3352 0.36218027 STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.44399646E-08 1.18476441E-07 -1.5383 1.4022 0.8479 0.8981 1.6335 1.5271 1.5738645166 LOC645166 lymphocyte-specific protein 1 pseudogene 0.00148162414 0.00396546598 -1.5386 0.2581 0.8336 0.4515 0.2324 0.4772 0.441364112 MOAP1 modulator of apoptosis 1 3.99766596E-07 2.28266726E-06 -1.5386 1.2951 5.9259 2.3310 1.0687 2.6955 3.066655812 SPATA7 spermatogenesis associated 7 0.00848423838 0.018711406606 -1.5392 0.6045 1.0271 0.5196 0.6794 1.2913 0.6452

4773 NFATC2 3.72447963E-07 2.15223567E-06 -1.5398 1.2558 2.2895 1.5454 0.8431 2.1991 1.46866138 RPL15 ribosomal protein L15 1.07240357E-09 1.24254648E-08 -1.5401 2.0576 1.6980 2.2860 1.6426 1.4631 1.583390843 TCEAL8 transcription elongation factor A (SII)-like 8 1.9733004E-08 1.56561637E-07 -1.5415 2.3864 1.2228 1.3203 2.2172 1.5390 1.874910152 ABI2 abl-interactor 2 2.23799312E-06 1.07981543E-05 -1.5417 0.5593 0.4119 0.4680 0.4804 0.6181 0.608910475 TRIM38 tripartite motif containing 38 1.72502203E-07 1.0805486E-06 -1.5419 1.5658 1.3868 1.2615 1.5824 1.3533 1.133264940 STAG3L4 stromal antigen 3-like 4 (pseudogene) 0.00450428323 0.01072901357 -1.5419 0.2229 0.9212 0.6302 0.0840 0.4249 0.5892100131211 TMEM194B transmembrane protein 194B 0.00027621309 0.000864502502 -1.5422 2.6766 1.9529 2.5123 2.3344 1.8802 3.081484222 TMEM191A transmembrane protein 191A (pseudogene) 0.00711081347 0.016014887687 -1.5426 2.3052 1.0945 1.1615 1.5190 0.9624 0.9201117155 CATSPER2 cation channel, sperm associated 2 0.01268547777 0.026584361709 -1.5440 0.1329 0.1842 0.2402 0.3023 0.1625 0.2284401207 C5orf63 hypothetical gene supported by AK126569 0.00590779775 0.013609087293 -1.5445 1.8235 1.4519 1.8895 1.4746 1.6823 2.090654532 USP53 ubiquitin specific peptidase 53 0.00024582542 0.000777652724 -1.5448 0.9737 1.5623 0.8602 1.2888 1.6260 1.097023318 ZCCHC11 zinc finger, CCHC domain containing 11 3.26856055E-08 2.4356908E-07 -1.5448 1.0131 0.8561 0.7490 1.2830 0.9895 1.02324194 MDM4 MDM4, p53 regulator 3.23009028E-06 1.50408281E-05 -1.5460 1.8534 1.2076 1.4487 1.6525 1.3262 1.5537388335 TMEM220 transmembrane protein 220 0.00451947898 0.010762403221 -1.5467 1.0908 1.8562 0.7917 0.2605 0.2830 0.525385444 LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 0.00683994031 0.015486913184 -1.5468 1.3193 1.5498 1.5073 1.3298 1.1286 1.542384680 ACCS 1-aminocyclopropane-1-carboxylate synthase 0.01271939044 0.026643207846 -1.5471 1.8555 1.6115 1.6209 1.3415 1.0406 1.195126207 PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 1.54248851E-07 9.76588705E-07 -1.5473 1.8185 1.4317 1.9032 1.3222 1.6517 2.89448481 OFD1 oral-facial-digital syndrome 1 8.06949825E-06 3.4595465E-05 -1.5478 9.7960 0.8015 0.2722 4.6713 1.2478 0.16049815 GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 2.35153827E-08 1.82451411E-07 -1.5481 2.1932 1.3853 1.7412 2.3903 1.9193 2.318584527 ZNF559 zinc finger protein 559 0.0061571996 0.014107128656 -1.5481 0.3911 0.4533 0.5518 1.5143 0.6864 0.2193256302 C17orf103 transcript expressed during hematopoiesis 2 0.00211870563 0.005464848842 -1.5486 1.2326 1.5542 1.5358 0.8352 1.1346 1.35089412 MED21 mediator complex subunit 21 0.00010762541 0.000367369985 -1.5507 2.2991 2.8389 1.4386 2.2147 3.0878 2.01596477 SIAH1 siah E3 ubiquitin protein ligase 1 0.00466897735 0.01107510763 -1.5509 1.3359 1.6562 1.3338 1.2489 1.7163 1.471154855 FAM46C family with sequence similarity 46, member C 0.00194029724 0.005044130729 -1.5516 1.7789 1.9018 1.5423 2.1441 2.4167 2.296255320 MIS18BP1 Q6P0N0,MIS18 binding protein 1 6.37526515E-08 4.43767028E-07 -1.5533 1.9371 2.2768 1.2698 2.0197 2.4932 1.9300112616 CMTM7 CKLF-like MARVEL transmembrane domain containing 7 4.77019202E-07 2.67587088E-06 -1.5544 1.7478 2.5462 1.8566 1.6767 2.3636 2.240154915 YTHDF1 YTH domain family, member 1 8.73964088E-09 7.57186904E-08 -1.5554 0.7924 0.8727 1.3930 0.7365 1.2777 1.450923054 NCOA6 nuclear receptor coactivator 6 5.73959146E-09 5.29933376E-08 -1.5559 0.8603 1.0637 0.5246 0.7375 1.1168 0.71159883 POM121 POM121 transmembrane nucleoporin 5.65396261E-07 3.1135987E-06 -1.5561 1.6331 1.1114 1.3132 1.5957 1.4627 1.631190799 CEP95 coiled-coil domain containing 45 4.77055792E-05 0.000174684638 -1.5563 2.5208 2.7842 1.2292 2.0058 3.4837 1.4208340371 NRBP2 nuclear receptor binding protein 2 0.00670424752 0.015209834951 -1.5593 0.3043 0.4480 0.4799 0.3262 0.4612 0.53779262 STK17B serine/threonine kinase 17b 2.75552466E-07 1.64109995E-06 -1.5598 2.3630 2.6238 2.1358 2.4021 2.4669 2.215893624 TADA2B transcriptional adaptor 2B 1.25236769E-06 6.38840383E-06 -1.5601 3.7544 1.6742 2.4097 2.4943 1.6221 2.87036217 RPS16 ribosomal protein S16 5.36397382E-08 3.79522655E-07 -1.5606 1.8418 2.6679 2.3266 2.0082 3.4311 2.12644046 LSP1 lymphocyte-specific protein 1 0.00014336286 0.000476190897 -1.5606 0.7690 0.8754 0.9304 0.6518 0.8318 0.8973144699 FBXL14 F-box and leucine-rich repeat protein 14 1.05571912E-05 4.40916567E-05 -1.5614 2.2385 3.1622 2.3433 2.4049 5.3235 2.816923360 FNBP4 formin binding protein 4 2.72524006E-08 2.0782799E-07 -1.5617 2.9854 2.3751 1.9344 2.4360 3.9728 3.467623471 TRAM1 translocation associated membrane protein 1 1.08736101E-06 5.62362311E-06 -1.5625 1.5176 4.3729 1.6338 1.1759 3.7629 2.6692

6874 TAF4 1.11263594E-06 5.73809875E-06 -1.5631 4.2621 4.4029 2.2085 2.8473 2.6875 2.7734137994 LETM2 leucine zipper-EF-hand containing transmembrane protein 2 0.00725918838 0.016288823549 -1.5637 2.4951 1.9672 1.6233 1.8885 2.2668 2.287283608 C18orf21 chromosome 18 open reading frame 21 5.50338713E-08 3.87954821E-07 -1.5650 2.1925 3.1104 2.2297 1.9739 3.5505 2.9710286144 TRIQK hypothetical protein LOC286144 0.01643277064 0.033266642057 -1.5658 0.7432 0.5125 0.6731 0.8692 0.6542 0.7390255783 PRR24 hypothetical protein LOC255783 0.00297219807 0.007402944815 -1.5658 1.2502 2.1330 2.0600 1.4143 3.2877 3.174255023 PHIP pleckstrin homology domain interacting protein 3.70404771E-08 2.72904676E-07 -1.5668 0.9560 1.4601 0.6225 1.1820 2.2493 1.0356254394 MCM9 minichromosome maintenance complex component 9 7.04073948E-05 0.000249851217 -1.5673 1.3359 1.4260 1.0367 1.2061 1.3445 1.0062340719 NANOS1 nanos homolog 1 (Drosophila) 0.00333724791 0.008199299964 -1.5678 0.7839 1.0556 1.2068 0.3750 0.7717 1.17318848 TSC22D1 TSC22 domain family, member 1 0.00106749676 0.002946865208 -1.5693 0.9180 1.3754 1.0326 0.9366 1.1860 1.6993100527964 LOC100527964 uncharacterized LOC100527964 0.01140367155 0.024220375059 -1.5707 0.0183 0.0934 0.1313 0.1671 0.0906 0.1612130507 UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 1.26664359E-08 1.05296231E-07 -1.5718 0.4789 0.4292 0.4318 0.5104 0.5738 0.5074124989 EFCAB13 EF-hand calcium binding domain 13 0.00686096383 0.01552874163 -1.5718 1.3265 1.0970 0.9476 1.3887 1.1194 1.12802948 GSTM4 glutathione S-transferase mu 4 0.00475820782 0.011269212357 -1.5720 0.3321 0.3321 0.3321 0.3970 0.3970 0.397023015 GOLGA8A golgin A8 family, member A 0.0046355409 0.011004365773 -1.5721 0.0863 0.0545 0.1552 0.3575 0.0483 0.18935532 PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 6.17595348E-09 5.63671439E-08 -1.5742 1.2121 1.3491 0.9576 0.9146 1.2434 1.232580856 KIAA1715 KIAA1715 1.48607576E-06 7.46387474E-06 -1.5744 1.8757 1.5449 1.5902 2.0979 2.0802 1.7608

27345 KCNMB4 0.00521558825 0.012211587453 -1.5751 2.6629 1.9354 1.7225 2.6004 2.1008 2.612423268 DNMBP dynamin binding protein 0.00481555872 0.011387328713 -1.5782 0.5407 0.6745 0.5756 0.4864 0.4058 0.54934674 NAP1L2 nucleosome assembly protein 1-like 2 0.0053768105 0.012528064446 -1.5787 2.1515 2.7668 2.2332 2.1299 2.7473 2.0251

glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa

HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa

potassium large conductance calcium-activated channel, subfamily M, beta member 4

23528 ZNF281 zinc finger protein 281 3.63408029E-06 1.67723958E-05 -1.5792 1.9946 2.4333 1.8394 2.4375 3.0418 2.181180264 ZNF430 zinc finger protein 430 0.00014205403 0.000472530718 -1.5793 1.5097 1.5416 1.9349 1.4303 3.3548 3.1565254170 FBXO33 F-box protein 33 2.13492192E-06 1.03472926E-05 -1.5803 2.2885 2.8303 1.6102 1.9152 4.7875 2.383364081 PBLD phenazine biosynthesis-like protein domain containing 0.00692622579 0.015647378551 -1.5809 1.1929 0.8869 0.7151 1.4780 1.2478 0.852179161 TMEM243 transmembrane protein 243, mitochondrial 1.49889898E-07 9.52290759E-07 -1.5820 2.1669 2.3658 1.3210 2.9476 4.9101 3.367610023 FRAT1 frequently rearranged in advanced T-cell lymphomas 0.00124411336 0.003386835406 -1.5821 1.6122 1.8281 2.1610 2.0952 1.2750 2.8970345462 ZNF879 zinc finger protein 879 0.00443686854 0.010584993064 -1.5825 1.6309 2.1841 1.3180 1.6669 2.2001 1.52461565 CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.01824307636 0.036434308794 -1.5826 0.1185 0.2043 0.1645 0.2070 0.0179 0.189525764 HYPK huntingtin interacting protein K 0.00735170172 0.016476179781 -1.5828 2.2504 3.8445 2.2104 1.6630 4.6565 1.6286389072 PLEKHM3 pleckstrin homology domain containing, family M, member 3 3.96541771E-05 0.000147678869 -1.5829 2.4606 2.0091 1.7960 2.2246 2.2019 2.075410520 ZNF211 zinc finger protein 211 0.00167672274 0.004426044201 -1.5840 1.1677 0.7739 0.8951 1.5187 1.1076 1.130255848 PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 9.19948632E-07 4.82332895E-06 -1.5845 3.1311 2.0793 2.1197 1.9275 1.5030 1.80854673 NAP1L1 nucleosome assembly protein 1-like 1 3.25043148E-09 3.24014643E-08 -1.5847 1.7994 1.3512 2.2493 1.7670 2.2083 2.9384583 BBS2 Bardet-Biedl syndrome 2 0.00027062658 0.000849199516 -1.5848 2.2712 3.0188 1.8547 2.4975 2.9852 1.65563013 HIST1H2AD histone cluster 1, H2ad 0.00093609787 0.002618150983 -1.5859 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970150590 C2orf15 chromosome 2 open reading frame 15 0.01872433486 0.037293552055 -1.5870 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970139716 GAB3 GRB2-associated binding protein 3 0.00269934856 0.006789991301 -1.5872 0.9809 1.4782 1.2833 0.6741 0.9982 1.082110944 C11orf58 chromosome 11 open reading frame 58 3.00965896E-07 1.77566963E-06 -1.5879 3.8333 0.0150 0.1796 2.5753 0.0864 0.2354171586 ABHD3 abhydrolase domain containing 3 4.05361374E-05 0.000150639502 -1.5889 6.4501 0.6021 0.5152 13.7386 1.3340 1.10614602 MYB v-myb avian myeloblastosis viral oncogene homolog 7.95743955E-05 0.000279773591 -1.5895 1.0812 0.6449 0.8921 1.1070 0.7037 1.26188883 NAE1 NEDD8 activating enzyme E1 subunit 1 1.09704257E-07 7.19237955E-07 -1.5910 1.8495 1.1827 1.1014 1.5967 1.3730 1.023626009 ZZZ3 zinc finger, ZZ-type containing 3 2.76348236E-09 2.81305569E-08 -1.5921 1.3119 1.4393 0.9701 1.5840 1.7171 1.34038631 SKAP1 src kinase associated phosphoprotein 1 2.52960941E-08 1.94451086E-07 -1.5923 1.8950 1.4946 1.5138 1.9863 1.7191 1.9137

3937 LCP2 2.61678088E-07 1.56715242E-06 -1.5931 2.4658 2.0848 1.8156 2.3146 2.8634 1.702755761 TTC17 tetratricopeptide repeat domain 17 4.46908408E-09 4.27982727E-08 -1.5933 0.7795 0.6773 0.6849 0.8753 0.6437 0.770954861 SNRK SNF related kinase 5.23660801E-08 3.71874472E-07 -1.5935 1.5221 0.8503 1.1944 1.7742 0.8618 1.15055930 RBBP6 retinoblastoma binding protein 6 9.73728956E-08 6.46510737E-07 -1.5946 0.6726 0.8174 0.4895 0.8377 1.1110 0.80814534 MTM1 myotubularin 1,myotubularin 1 1.12290825E-06 5.78454457E-06 -1.5958 1.8989 1.8168 1.3665 1.4485 3.0697 1.906084163 GTF2IRD2 GTF2I repeat domain containing 2 0.00011166889 0.000379894601 -1.5965 1.0631 1.5626 0.8374 1.1405 2.3466 0.98411031 CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00327276677 0.008058212417 -1.5967 1.8701 2.4523 1.4724 1.6670 2.4122 2.23509683 N4BP1 NEDD4 binding protein 1 2.49143057E-08 1.91839104E-07 -1.5974 1.4634 2.3149 2.0323 1.2662 2.5260 2.806084833 USMG5 up-regulated during skeletal muscle growth 5 homolog (mouse) 2.14503494E-07 1.31303445E-06 -1.5990 1.5096 3.9545 3.2364 0.3432 1.8810 1.6921158880 USP51 ubiquitin specific peptidase 51 0.00385379675 0.009324228585 -1.5990 2.2739 1.7540 1.8874 2.3439 2.5330 1.942410175 CNIH1 cornichon family AMPA receptor auxiliary protein 1 2.54901639E-06 1.21448833E-05 -1.5993 1.8342 2.0322 2.1530 1.1531 1.8495 2.009592342 METTL18 methyltransferase like 18 0.00352656131 0.008620378353 -1.5994 0.3321 0.3321 0.3321 0.3970 0.3970 0.397056260 C8orf44 chromosome 8 open reading frame 44 0.02165896808 0.042290304 -1.5995 0.2926 0.3617 0.4715 0.4707 0.2947 0.375010044 SH2D3C SH2 domain containing 3C 1.06198087E-05 4.43329096E-05 -1.6018 0.9641 1.5491 0.9091 0.8525 1.1321 1.04023459 IFNGR1 interferon gamma receptor 1 0.00041835148 0.001257049546 -1.6022 2.3262 2.4168 1.6293 1.8972 3.2788 1.4802643641 ZNF862 zinc finger protein 862 2.53569904E-06 1.20877362E-05 -1.6028 1.5012 2.1315 1.1610 1.1634 3.5050 1.5442643749 TRAF3IP2-AS1 TRAF3IP2 antisense RNA 1 0.00516878211 0.012111623969 -1.6033 0.3321 0.3321 0.3321 0.3970 0.3970 0.397025816 TNFAIP8 tumor necrosis factor, alpha-induced protein 8 1.45004081E-06 7.29893822E-06 -1.6036 2.3915 2.3400 1.9576 2.1425 2.2305 2.0978158234 TRMT10B tRNA methyltransferase 10 homolog B (S. cerevisiae) 0.00127217737 0.003457053087 -1.6043 1.9969 2.1178 2.0239 1.6019 3.0464 1.82408831 SYNGAP1 synaptic Ras GTPase activating protein 1 3.07144859E-06 1.43753864E-05 -1.6044 0.5325 0.6441 0.6992 0.4510 0.4675 0.58673423 IDS iduronate 2-sulfatase 2.1202264E-07 1.30133614E-06 -1.6048 1.0563 0.4077 0.7796 1.1372 0.5981 0.5682440270 GOLGA8B golgin A8 family, member B 0.00386013892 0.009337100663 -1.6053 0.0417 0.0365 0.2429 0.2970 0.0194 0.26986018 RLF rearranged L-myc fusion 1.28023312E-08 1.06377533E-07 -1.6055 1.0788 0.7131 1.2300 1.1119 1.0241 1.379610499 NCOA2 nuclear receptor coactivator 2 2.66253838E-08 2.03470938E-07 -1.6067 1.2380 1.1710 1.4407 1.3229 1.2973 1.70235978 REST RE1-silencing transcription factor 9.22465437E-08 6.16506527E-07 -1.6071 2.3582 2.2944 1.4633 1.9371 2.5370 2.00791789 DNMT3B DNA nucleotidylexotransferase 0.02115311196 0.041462096303 -1.6074 0.3537 0.8549 0.6579 0.2858 0.4877 0.6111284309 ZNF776 zinc finger protein 776 9.16273189E-05 0.000317146121 -1.6074 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706314 ATXN7 ataxin 7 1.93274787E-09 2.06159773E-08 -1.6076 1.2006 1.8679 1.1573 1.1330 1.5755 1.10539821 RB1CC1 RB1-inducible coiled-coil 1 1.84074783E-07 1.14596744E-06 -1.6076 2.7200 3.9344 1.6788 2.5864 4.9350 2.86727059 THBS3 thrombospondin 3 0.0047845538 0.011321337358 -1.6085 0.3196 0.6413 0.8517 0.1713 0.6630 0.405310677 AVIL advillin 0.01456893221 0.029981251198 -1.6098 0.0802 0.0698 0.2737 0.2015 0.0441 0.2557728939 PDZK1P1 PDZ domain containing 1 pseudogene 1 0.01201183593 0.025338289782 -1.6098 0.1554 0.1140 0.2764 0.4059 0.1283 0.2394

257397 TAB3 mitogen-activated protein kinase kinase kinase 7 interacting protein 3 3.61028192E-09 3.54958945E-08 -1.6100 1.0186 1.7122 0.9419 0.8849 2.0576 1.18834335 MNT MAX network transcriptional repressor 1.05304988E-07 6.92881796E-07 -1.6101 1.9815 1.5024 1.4994 2.3138 2.8434 3.014964863 METTL4 methyltransferase like 4 8.05644511E-05 0.000282982247 -1.6101 0.4538 6.7611 0.8605 0.3864 1.9458 2.0722847 CAT catalase 5.7597307E-06 2.54946219E-05 -1.6110 1.4380 1.3536 1.5824 1.3508 1.2460 1.71902811 GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.00651178071 0.014833967964 -1.6124 0.2522 0.3086 0.3566 0.4273 0.0670 0.1647644353 ZCCHC18 zinc finger, CCHC domain containing 18 0.01155081689 0.024510106407 -1.6132 2.2636 1.4481 1.4616 1.6592 1.1189 1.3978253260 RICTOR rapamycin-insensitive companion of mTOR 1.48210434E-09 1.64326521E-08 -1.6140 2.2274 2.1302 1.9870 2.4797 2.6492 3.78067111 TMOD1 tropomodulin 1 0.00594864747 0.013694555445 -1.6148 0.8218 0.6709 1.1151 0.3885 0.5460 0.692210048 RANBP9 RAN binding protein 9 6.01594918E-07 3.2970433E-06 -1.6155 1.6302 2.2509 1.3568 1.9037 3.1009 1.6216100507634 LOC100507634 uncharacterized LOC100507634 0.01382747555 0.028652260513 -1.6157 16.2202 5.5119 3.3161 14.2930 5.4283 1.09397871 SLMAP sarcolemma associated protein 1.96999487E-09 2.09277594E-08 -1.6159 0.7087 0.5907 0.5860 0.5336 0.6428 0.581611179 ZNF277 zinc finger protein 277 2.00211279E-06 9.76577813E-06 -1.6160 2.0708 3.1987 1.6268 0.8868 1.6350 0.898854778 RNF111 ring finger protein 111 1.45253834E-09 1.6124411E-08 -1.6181 0.7519 0.7348 0.5314 0.8574 1.0410 0.80569349 RPL23 ribosomal protein L23 1.13881115E-08 9.58910479E-08 -1.6181 2.7660 2.6608 3.5872 3.0378 2.9750 3.085223116 FAM179B family with sequence similarity 179, member B 5.47969269E-05 0.000198306486 -1.6198 1.9594 2.7725 2.9258 1.0647 1.0255 2.6874122809 SOCS4 suppressor of cytokine signaling 4 2.92000254E-06 1.3729873E-05 -1.6201 7.7282 5.6176 1.8234 2.5174 4.8567 1.428527128 CYTH4 cytohesin 4 0.00015324038 0.000505051996 -1.6204 4.0641 2.0747 2.3162 3.6944 2.3539 2.06937342 UBP1 upstream binding protein 1 (LBP-1a) 2.09647757E-08 1.65258145E-07 -1.6205 3.3026 1.8326 1.6719 4.3011 3.7057 4.0293258010 SVIP hypothetical protein DKFZp313A2432 7.53066292E-07 4.03283332E-06 -1.6207 1.5901 1.7842 1.0032 1.9991 2.7861 1.5576729013 ZBED5-AS1 ZBED5 antisense RNA 1 0.00462310362 0.01098054716 -1.6211 2.5971 1.5066 2.0099 2.8543 1.1893 2.471164327 LMBR1 limb development membrane protein 1 9.25914632E-08 6.18359362E-07 -1.6213 1.5162 1.1210 0.6564 1.4644 0.8924 0.936826091 HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 1.62928572E-08 1.31902121E-07 -1.6216 1.5451 1.2609 0.6752 1.4266 1.3571 0.8148329 BIRC2 baculoviral IAP repeat containing 2 1.5064073E-09 1.66818632E-08 -1.6219 2.5325 3.0008 2.4376 2.8361 4.9000 3.58478445 DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.99354428E-06 9.73437765E-06 -1.6221 1.8888 2.2919 1.6439 2.1695 2.9145 2.4365374899 ZNF829 zinc finger protein 829 0.00152021711 0.004057465235 -1.6221 0.5714 0.7194 0.6561 1.2090 0.4404 0.620855266 TMEM19 transmembrane protein 19 4.91151474E-06 2.20817789E-05 -1.6231 3.5421 1.7512 1.7076 2.7503 1.9793 1.6546204851 HIPK1 homeodomain interacting protein kinase 1 2.16333904E-07 1.3220322E-06 -1.6239 0.9452 1.0071 0.6595 1.0246 1.2863 0.78875094 PCBP2 poly(rC) binding protein 2 6.20609093E-08 4.33477421E-07 -1.6249 0.6690 0.5460 0.6913 0.7478 0.6699 0.717155901 THSD1 thrombospondin, type I, domain containing 1 0.00556225648 0.012909484404 -1.6252 0.6531 1.4394 0.7192 0.5597 1.2428 0.529064798 DEPTOR DEP domain containing MTOR-interacting protein 0.00483235389 0.011418726385 -1.6271 1.5079 2.4776 2.0114 1.5491 1.7151 2.71204012 LNPEP leucyl/cystinyl aminopeptidase 9.76384336E-07 5.09146535E-06 -1.6276 1.5063 2.7596 1.5513 1.7214 4.3904 2.3371867 CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 8.96387915E-08 6.00836389E-07 -1.6278 1.8175 2.0694 1.6294 1.4685 2.2303 2.4323146880 LOC146880 hypothetical protein MGC40489 1.16848047E-05 4.83261094E-05 -1.6282 0.7434 1.9580 1.8032 0.4360 1.7335 1.6501112487 DTD2 chromosome14 open reading frame 126 4.12489718E-05 0.000153066859 -1.6284 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702778 GNAS GNAS complex locus 9.08720504E-10 1.08099877E-08 -1.6291 0.9669 1.2975 0.8833 0.9363 1.6940 1.095857579 FAM135A family with sequence similarity 135, member A 0.00012977854 0.000435263125 -1.6292 0.4016 0.5638 0.4478 0.4424 0.6243 0.640455844 PPP2R2D protein phosphatase 2, regulatory subunit B, delta 5.56861569E-08 3.92099213E-07 -1.6304 0.3752 0.2181 0.2512 0.3677 0.4306 0.2621221092 HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 7.24175513E-09 6.43273455E-08 -1.6314 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

4724 NDUFS4 5.74611287E-09 5.30080124E-08 -1.6315 1.7253 1.7514 1.2086 2.1516 2.2058 1.4943340252 ZNF680 zinc finger protein 680 0.00311767233 0.007726313411 -1.6319 1.9579 2.0541 1.4410 1.9433 3.0062 2.386280097 MZT2B mitotic spindle organizing protein 2B 1.14602091E-07 7.48127688E-07 -1.6320 1.9437 1.3103 2.2867 3.0025 1.9203 4.129628972 SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 1.72305018E-07 1.07968357E-06 -1.6323 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970100131564 LOC100131564 uncharacterized LOC100131564 0.00497242786 0.011706764821 -1.6332 0.3952 3.7046 0.5909 0.2209 0.2358 1.213791860 CALML4 calmodulin-like 4 3.19221033E-05 0.000120562355 -1.6334 0.6339 1.2374 0.8550 0.3216 0.4451 0.6526

55512 SMPD3 0.0118051488 0.024975400982 -1.6361 0.4393 0.6098 0.8294 0.3575 0.3417 0.7015116843 SLC18B1 solute carrier family 18, subfamily B, member 1 0.00037923509 0.001150596551 -1.6367 1.6474 1.2561 0.8951 1.5342 1.2881 0.8084

55808 ST6GALNAC1 0.01047983458 0.022504117685 -1.6374 1.3555 0.9238 0.7655 1.0794 0.3532 0.636855014 STX17 syntaxin 17 2.62596231E-09 2.68653882E-08 -1.6383 3.2454 1.1324 0.1061 1.7770 0.4420 0.121257091 CASS4 chromosome 20 open reading frame 32 0.00577499579 0.013340167265 -1.6394 2.5039 1.5480 2.1900 1.7511 1.4835 1.2912377677 CA13 carbonic anhydrase XIII 0.00638037151 0.014570947163 -1.6400 1.7571 1.8873 1.8785 1.1407 0.9557 1.23366167 RPL37 ribosomal protein L37 9.16388662E-09 7.90768148E-08 -1.6404 2.4622 1.3071 2.1565 2.8320 2.3896 2.924926065 LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 1.4688799E-07 9.34518578E-07 -1.6411 1.0744 1.8306 0.8991 1.0505 2.3144 1.1887150381 LOC150381 uncharacterized LOC150381 0.00326288054 0.008038203215 -1.6416 0.3321 0.3321 0.3321 0.3970 0.3970 0.397054847 SIDT1 SID1 transmembrane family, member 1 0.00077120853 0.002192891742 -1.6417 0.6750 0.9065 0.7042 1.0287 1.1644 1.036384146 ZNF644 zinc finger protein 644 5.03503374E-09 4.73739117E-08 -1.6425 2.1888 3.1624 1.7089 2.1465 3.4741 1.97331540 CYLD cylindromatosis (turban tumor syndrome) 1.27730532E-07 8.23532914E-07 -1.6438 1.3247 2.5498 1.1849 1.0656 1.7148 1.1213843 CASP10 caspase 10, apoptosis-related cysteine peptidase 6.00301459E-05 0.000215707144 -1.6440 2.2984 1.3624 1.7848 2.2921 1.1641 1.93479885 OSBPL2 oxysterol binding protein-like 2 4.69609012E-09 4.48078113E-08 -1.6464 0.5889 0.7362 0.9368 0.4637 0.7616 0.5884373156 GSTK1 glutathione S-transferase kappa 1 4.55081473E-06 2.05365489E-05 -1.6474 3.2402 1.8619 1.9669 3.3180 2.2271 2.9011283149 BCL9L B-cell CLL/lymphoma 9-like 2.08414894E-05 8.18430461E-05 -1.6482 5.0332 3.3456 2.2071 3.3979 2.4650 1.465923527 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 8.14174907E-09 7.11458819E-08 -1.6499 1.3178 3.0721 1.9934 1.5199 3.3847 2.696955632 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 1.22544355E-06 6.26330198E-06 -1.6503 1.4645 1.2300 1.1424 1.4478 1.5491 1.46246515 SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00122851393 0.003348360157 -1.6508 2.2074 3.2506 1.6137 3.1511 5.5710 1.8924286530 P2RY8 purinergic receptor P2Y, G-protein coupled, 8 7.02750462E-06 3.05076181E-05 -1.6512 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

728609 SDHAP3 1.54855591E-05 6.24618401E-05 -1.6521 0.7249 0.6972 0.7113 0.6390 0.5643 1.012454165 DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 9.70649092E-08 6.44700117E-07 -1.6521 2.1889 1.6623 2.2834 2.2592 2.2533 2.715880325 ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 0.00038347075 0.001162179071 -1.6523 0.6099 1.0000 0.9768 0.5872 1.0186 1.1401100101267 POM121C POM121 transmembrane nucleoporin C 1.22836415E-07 7.94782922E-07 -1.6539 2.3264 2.6283 2.0559 2.1102 2.4450 2.06806194 RPS6 ribosomal protein S6 9.09197645E-09 7.86221456E-08 -1.6574 2.5631 3.3349 2.1397 2.1393 3.9891 2.6702163882 CNST chromosome 1 open reading frame 71 1.37447396E-07 8.80897517E-07 -1.6577 8.1731 6.7565 2.1210 8.1275 7.7359 2.5555388677 NOTCH2NL notch 2 N-terminal like 2.85793009E-05 0.000109018995 -1.6581 0.4314 0.4743 0.3227 0.3664 0.3697 0.30511998 ELF2 E74-like factor 2 (ets domain transcription factor) 1.4365919E-08 1.1802791E-07 -1.6587 0.5051 1.2437 0.5095 0.6134 1.9190 0.6776151011 SEPT10 septin 10 0.02048709516 0.040277620272 -1.6589 1.6790 2.8419 0.4743 5.5044 0.8350 0.341779567 FAM65A family with sequence similarity 65, member A 1.73980813E-06 8.61745032E-06 -1.6596 1.1919 1.5683 1.3547 0.6272 1.1175 1.3419119016 AGAP4 centaurin, gamma-like family, member 1 0.00030443851 0.000944912591 -1.6597 0.0510 0.1720 0.3562 0.3521 0.0576 0.2237100505876 LOC100505876 uncharacterized LOC100505876 1.36222637E-08 1.12678136E-07 -1.6600 2.4535 2.0975 1.2779 2.8661 1.6242 1.8071125488 TTC39C tetratricopeptide repeat domain 39C 6.68957633E-06 2.91792644E-05 -1.6601 1.3264 2.1234 1.0909 0.9039 2.4454 1.050026019 UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 6.06117227E-10 7.66251973E-09 -1.6613 1.4054 1.4140 1.0553 1.3175 2.4676 1.48851896 EDA polyhomeotic homolog 1 (Drosophila) 0.00291113682 0.007263729614 -1.6635 1.0801 1.0617 0.9234 0.8790 1.6028 1.12239931 HELZ helicase with zinc finger 3.1700111E-08 2.36901606E-07 -1.6648 0.9636 0.7886 0.8266 1.0159 0.8573 1.221355892 MYNN myoneurin 7.26507577E-09 6.44718138E-08 -1.6658 1.1573 1.3227 1.0700 1.4654 1.9009 1.41686205 RPS11 ribosomal protein S11 2.07887863E-07 1.27853485E-06 -1.6660 1.7861 1.4018 2.0667 2.1776 2.2287 2.678123588 KLHDC2 kelch domain containing 2 2.21260267E-07 1.34852155E-06 -1.6671 2.4439 3.0686 1.8465 2.2101 3.1723 2.3945

lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)

NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)

sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1

succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3

93550 ZFAND4 zinc finger, AN1-type domain 4 0.00013053968 0.000437173953 -1.6677 1.0314 1.6127 0.9275 1.1121 2.5958 1.306084033 OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.00019742225 0.000635423517 -1.6678 0.0686 0.0598 0.2263 0.1333 0.1050 0.269184062 DTNBP1 dystrobrevin binding protein 1 5.10086646E-07 2.83809476E-06 -1.6694 2.1491 1.0500 1.1184 1.7648 1.6125 1.564355728 N4BP2 NEDD4 binding protein 2 1.95018037E-08 1.5506395E-07 -1.6697 0.5982 1.6770 1.0243 0.5860 0.8104 2.11581073 CFL2 cofilin 2 (muscle) 0.00231149344 0.005905426196 -1.6703 2.3020 1.3034 1.0583 1.7890 0.7066 1.2514994 CDC25B cell division cycle 25B 3.85668859E-06 1.77014353E-05 -1.6710 1.4485 1.4805 1.1254 1.0119 0.9563 1.0785100132247 NPIPB5 nuclear pore complex interacting protein family, member B5 0.00018168009 0.00058911421 -1.6716 0.1064 0.0786 0.2730 0.3107 0.0994 0.230429068 ZBTB44 zinc finger and BTB domain containing 44 7.56335763E-09 6.67621597E-08 -1.6720 1.5827 1.8444 0.9959 1.6158 1.5261 1.311288455 ANKRD13A ankyrin repeat domain 13A 2.04370354E-08 1.61516224E-07 -1.6721 0.9224 0.7811 0.8758 0.9688 0.9096 0.72595753 PTK6 protein tyrosine kinase 6 0.02155306497 0.042101518405 -1.6722 0.4295 0.8821 0.8463 0.3857 0.7423 0.731551773 RSF1 remodeling and spacing factor 1 3.94538044E-10 5.31637105E-09 -1.6728 1.0201 0.9485 1.6656 1.4388 1.5465 4.438454454 ATAD2B ATPase family, AAA domain containing 2B 7.21533129E-09 6.41862383E-08 -1.6736 1.4874 2.7074 0.2840 1.3269 2.3626 0.899057187 THOC2 THO complex 2 1.30676216E-09 1.48213272E-08 -1.6745 0.5309 1.0163 0.4288 0.8790 2.2933 0.7423100128822 LINC01003 long intergenic non-protein coding RNA 1003 0.00182952098 0.004779669341 -1.6763 1.7184 2.3903 1.6832 1.9682 3.7142 3.172523558 WBP2 WW domain binding protein 2 3.01937279E-08 2.26663844E-07 -1.6793 1.9913 4.3335 2.3523 1.6614 3.9938 2.7790388931 MFSD2B major facilitator superfamily domain containing 2B 0.00642721818 0.014666932753 -1.6801 0.1256 0.2242 0.5242 0.1434 0.1140 0.3540132321 C4orf33 chromosome 4 open reading frame 33 0.00415882399 0.009996057874 -1.6810 1.8000 1.1566 1.0585 2.9094 1.1722 1.06409628 RGS6 regulator of G-protein signaling 6 0.02559650805 0.048810206123 -1.6813 0.1412 0.3192 0.5724 0.2316 0.2603 0.348884324 SARNP SAP domain containing ribonucleoprotein 0.00054553147 0.001597061275 -1.6872 10.9203 4.7970 1.1571 9.0212 3.0508 1.505811016 ATF7 activating transcription factor 7 4.76395674E-09 4.52898114E-08 -1.6876 2.7989 2.0987 2.0465 1.6154 1.4187 1.582822832 KIAA1009 KIAA1009 0.0030792012 0.007643413171 -1.6878 0.8570 1.1690 0.8137 1.3726 1.7394 1.0375

730092 RRN3P1 0.00021274181 0.000680297238 -1.6894 2.7155 2.5309 1.8736 2.1273 3.1070 1.9878100526737 RBM14-RBM4 RBM14-RBM4 readthrough 0.00685441998 0.015515852554 -1.6903 0.3321 0.3321 0.3321 0.3970 0.3970 0.397010285 SMNDC1 survival motor neuron domain containing 1 2.11287805E-08 1.66335665E-07 -1.6906 1.9402 3.5260 1.1204 2.1336 3.6757 1.5319246175 CNOT6L CCR4-NOT transcription complex, subunit 6-like 1.75924708E-06 8.70665296E-06 -1.6910 0.9426 1.4480 0.7777 1.7608 2.1965 2.4508

4214 MAP3K1 1.49370712E-06 7.50014191E-06 -1.6911 1.4304 4.6974 1.5198 1.9264 3.5086 2.2079221035 REEP3 receptor accessory protein 3 4.43777879E-07 2.50733129E-06 -1.6913 2.0130 1.7062 1.8945 1.8902 2.6397 2.790055609 ZNF280C zinc finger protein 280C 0.00120166801 0.003284990711 -1.6920 1.5513 1.1662 1.3812 1.6414 1.2305 2.2300165631 PARP15 poly (ADP-ribose) polymerase family, member 15 0.0019309439 0.005023093233 -1.6928 0.8359 0.9094 0.6592 0.8037 0.8606 0.4693147727 ILF3-AS1 ILF3 antisense RNA 1 (head to head) 4.21326832E-06 1.91361767E-05 -1.6932 4.4387 2.2591 2.9577 2.9668 2.1861 2.9114

2197 FAU 9.70323223E-10 1.14131986E-08 -1.6939 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706799 SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 0.02511794264 0.048048057773 -1.6941 0.1574 0.2850 0.2197 0.1604 0.0732 0.296851455 REV1 REV1, polymerase (DNA directed) 4.15624635E-09 4.02240113E-08 -1.6943 1.0462 2.0974 1.1257 1.1213 2.8071 1.9452150094 SIK1 salt-inducible kinase 1 0.02347441501 0.04532169389 -1.6944 1.0054 1.1262 2.4176 0.9371 2.1095 3.0993728448 PPIEL peptidylprolyl isomerase E-like pseudogene 0.00260070166 0.006569890889 -1.6957 0.9394 0.8314 0.6459 0.9770 0.8817 0.541925950 RWDD3 RWD domain containing 3 0.0026612825 0.006706241056 -1.6966 0.3321 0.3321 0.3321 0.3970 0.3970 0.397079865 TREML2 triggering receptor expressed on myeloid cells-like 2 0.01159581038 0.024599866173 -1.6978 1.9006 1.5399 2.0470 0.9862 0.7974 1.48366143 RPL19 ribosomal protein L19 1.12492338E-08 9.48965839E-08 -1.7021 2.0667 2.7322 2.4156 1.9755 2.6719 2.916754617 INO80 INO80 complex subunit 4.25945816E-10 5.67265449E-09 -1.7027 1.2295 1.0974 1.0310 1.3402 1.8302 1.58907259 TSPYL1 TSPY-like 1 8.52618507E-08 5.75935134E-07 -1.7043 0.3321 0.3321 0.3321 0.3970 0.3970 0.397023331 TTC28 tetratricopeptide repeat domain 28 0.00513292158 0.012044271616 -1.7049 0.3937 0.3871 1.0746 0.3335 0.2727 0.771523521 RPL13A ribosomal protein L13a 2.50812978E-07 1.50751801E-06 -1.7050 2.2026 1.9587 1.2498 2.2952 4.5013 1.697781619 TSPAN14 tetraspanin 14 1.4989255E-05 6.05937319E-05 -1.7081 0.6939 1.6246 1.3877 0.8261 1.7208 1.72108899 PRPF4B pre-mRNA processing factor 4B 9.81622534E-10 1.14975685E-08 -1.7088 1.3020 1.4788 1.0612 1.0621 1.4807 1.250379893 GGNBP2 gametogenetin binding protein 2 1.56326983E-09 1.72176409E-08 -1.7089 0.9972 2.1111 0.7317 0.9788 3.0784 1.6639142891 SAMD8 sterile alpha motif domain containing 8 4.18187464E-09 4.04292134E-08 -1.7107 1.8972 1.3976 1.6037 1.8117 1.9084 2.9709400960 PCBP1-AS1 PCBP1 antisense RNA 1 0.00044336622 0.001323290997 -1.7116 0.9307 0.9899 1.0800 0.8222 1.1484 0.9339149483 CCDC17 coiled-coil domain containing 17 0.0058997322 0.013592221261 -1.7117 0.0750 0.0939 0.1554 0.2343 0.0357 0.248681794 ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 0.02057647161 0.040444630941 -1.7123 1.5183 2.8550 1.4873 0.9937 2.1470 1.62403845 KRAS Kirsten rat sarcoma viral oncogene homolog 3.9388584E-07 2.25613858E-06 -1.7125 2.3588 3.0264 1.9894 1.7123 3.8276 1.90535445 PON2 paraoxonase 2 0.00315973969 0.007818900812 -1.7128 1.6695 1.8215 1.4294 1.3280 2.0208 1.1391246126 TXLNG2P chromosome Y open reading frame 15A 0.00028152341 0.000879616245 -1.7128 2.4080 4.6088 1.1182 1.5024 4.6911 1.481810446 LRRN2 leucine rich repeat neuronal 2 0.01397224141 0.028922713847 -1.7154 0.8464 0.9013 0.6772 0.5486 1.2362 0.66487454 WAS Wiskott-Aldrich syndrome 6.69395752E-09 6.04905993E-08 -1.7162 1.8899 2.2948 3.2119 1.4442 2.3183 2.684411120 BTN2A1 butyrophilin, subfamily 2, member A1 2.39724028E-05 9.27426941E-05 -1.7174 1.7492 2.8417 1.7476 1.8926 2.6706 2.1418158219 TTC39B tetratricopeptide repeat domain 39B 2.67178459E-07 1.594866E-06 -1.7182 0.5276 0.6030 0.5392 0.6113 0.6897 0.6381388524 RPSAP15 ribosomal protein SA pseudogene 58 2.53705428E-09 2.60432897E-08 -1.7190 2.0160 3.3893 1.8175 2.3014 3.7463 2.12779337 CNOT8 CCR4-NOT transcription complex, subunit 8 9.78777895E-09 8.36493438E-08 -1.7192 2.4428 4.1167 1.6862 2.7523 6.0654 3.045723533 PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 7.91943991E-05 0.000278652043 -1.7199 0.8487 1.1537 1.2406 0.9601 1.6709 1.7862399715 LOC399715 uncharacterized LOC399715 0.00766849846 0.017114792225 -1.7219 0.1574 0.4579 0.4446 0.2476 0.4646 0.5816

51809 GALNT7 2.47140065E-07 1.4878968E-06 -1.7221 1.4116 0.8796 0.9217 1.1568 1.0639 1.0961647087 C7orf73 hypothetical LOC647087 5.04678295E-08 3.59652177E-07 -1.7225 2.3850 1.8762 1.8392 1.8130 3.0512 1.853255840 EAF2 ELL associated factor 2 0.00053651021 0.001574527089 -1.7231 22.9284 2.7454 1.9726 22.3004 1.2754 1.427128978 TMEM14A transmembrane protein 14A 8.4000904E-06 3.58613205E-05 -1.7238 1.4880 1.3489 1.8563 1.2731 1.9177 1.79995562 PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 9.76190564E-10 1.1441279E-08 -1.7243 2.8454 1.6613 1.6792 3.3328 2.0331 1.80249655 SOCS5 suppressor of cytokine signaling 5 1.48107902E-05 5.99253231E-05 -1.7248 1.4739 3.0859 1.6197 1.4260 3.1904 1.72677840 ALMS1 Alstrom syndrome 1 2.79893109E-06 1.3211591E-05 -1.7249 0.8638 0.9094 0.7605 0.6935 0.9648 1.010757685 CACHD1 cache domain containing 1 0.02167659212 0.042312157313 -1.7251 0.7457 1.0590 1.0329 0.6549 0.6283 0.895651427 ZNF107 zinc finger protein 107 2.72070212E-06 1.28755942E-05 -1.7253 1.9774 2.5846 1.7112 1.8553 2.8594 2.142922862 FNDC3A fibronectin type III domain containing 3A 4.09603747E-10 5.48298877E-09 -1.7264 2.3468 1.8439 1.1340 2.0971 2.0871 1.516683988 NCALD neurocalcin delta 0.00760808341 0.01699656438 -1.7268 0.9673 1.7753 0.9985 0.8481 1.7659 1.10366239 RREB1 ras responsive element binding protein 1 2.8983238E-08 2.19107044E-07 -1.7268 0.8403 1.0046 0.8872 1.1030 1.3860 1.3620130814 PQLC3 PQ loop repeat containing 3 1.96032732E-06 9.59268902E-06 -1.7271 1.7044 2.2356 1.6785 1.5193 2.2272 2.0105

79158 GNPTAB 2.73514194E-07 1.6294918E-06 -1.7279 1.0675 1.0772 0.8327 0.8978 0.9129 1.10109541 CIR1 corepressor interacting with RBPJ, 1 1.59687846E-05 6.4254929E-05 -1.7296 0.4112 1.4566 0.2983 0.4025 0.3264 0.37286856 SYPL1 synaptophysin-like 1 3.09023627E-09 3.09905582E-08 -1.7296 2.5257 2.4889 1.8238 2.6094 2.9882 1.963280315 CPEB4 cytoplasmic polyadenylation element binding protein 4 3.98045888E-06 1.8187283E-05 -1.7305 1.5177 1.1745 1.2506 1.2813 1.1067 1.2385677 ZFP36L1 ZFP36 ring finger protein-like 1 2.42594583E-05 9.37341555E-05 -1.7310 1.8241 2.0810 1.9076 1.9541 2.5883 2.237758155 PTBP2 polypyrimidine tract binding protein 2 8.15341546E-05 0.00028600347 -1.7312 0.8992 1.4192 0.8411 0.9241 1.2835 1.1764343099 CCDC18 coiled-coil domain containing 18 0.00063621107 0.001835599037 -1.7323 1.1793 0.3088 2.5703 1.0748 0.1505 1.7668146691 TOM1L2 target of myb1-like 2 (chicken) 2.39819186E-06 1.14982319E-05 -1.7347 4.9748 3.6486 3.0787 2.5094 3.0646 1.69019289 GPR56 G protein-coupled receptor 56 0.01834969007 0.036631217842 -1.7357 0.1102 0.2517 0.6525 0.1802 0.0747 0.461323593 HEBP2 heme binding protein 2 1.86912831E-09 2.00898309E-08 -1.7374 1.9998 2.5840 2.0638 2.0119 1.8402 2.683410672 GNA13 guanine nucleotide binding protein (G protein), alpha 13 2.56789758E-08 1.97062682E-07 -1.7376 1.8136 2.0546 1.7589 1.9428 3.1473 2.09389736 USP34 ubiquitin specific peptidase 34 1.15361577E-08 9.69589118E-08 -1.7377 0.7099 0.4822 0.4796 0.8284 0.7062 1.0883192670 AGO4 eukaryotic translation initiation factor 2C, 4 1.07591698E-05 4.48785837E-05 -1.7382 1.3239 2.6161 1.8428 1.0356 2.1903 1.54313669 ISG20 interferon stimulated exonuclease gene 20kDa 0.00353468229 0.008633299662 -1.7407 2.4582 2.3625 2.2866 1.5295 1.7026 1.4195374739 TEPP testis, prostate and placenta expressed 0.01375062958 0.028509191381 -1.7421 0.1422 0.0432 0.1035 0.2781 0.0513 0.172255796 MBNL3 muscleblind-like splicing regulator 3 2.16407526E-07 1.3220322E-06 -1.7424 0.9669 0.7067 0.6036 0.9912 0.6539 0.7826254251 LCORL ligand dependent nuclear receptor corepressor-like 0.00219145445 0.005627864469 -1.7440 1.0558 1.8294 1.1323 1.0766 2.1841 1.955551668 HSPB11 heat shock protein family B (small), member 11 1.60272294E-08 1.30039758E-07 -1.7446 2.8278 4.2169 2.3620 2.0396 6.9322 2.281983473 KATNAL2 katanin p60 subunit A-like 2 0.00619160078 0.014182390553 -1.7456 0.8362 1.2280 0.7475 0.6956 0.7680 0.718251574 LARP7 La ribonucleoprotein domain family, member 7 4.43737211E-07 2.50733129E-06 -1.7461 1.9143 5.9936 1.4295 0.8955 4.6263 0.69876655 SOS2 son of sevenless homolog 2 (Drosophila) 1.0364602E-06 5.38169959E-06 -1.7462 0.5911 0.9500 0.4743 0.7780 1.2283 0.8342143 PARP4 poly (ADP-ribose) polymerase family, member 4 8.62933895E-05 0.000300964461 -1.7462 2.4819 1.8053 1.4967 2.7473 1.7761 2.139311257 TP53TG1 TP53 target 1 (non-protein coding) 7.69821901E-05 0.000271390812 -1.7463 4.0539 2.9317 2.9510 2.5353 1.3265 1.3639100507547 LOC100507547 uncharacterized LOC100507547 0.01169914415 0.024790300577 -1.7464 0.3321 0.3321 0.3321 0.3970 0.3970 0.397050515 CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.49507792E-08 1.92039022E-07 -1.7469 1.7737 1.2795 1.5529 2.1400 1.6694 2.38219802 DAZAP2 DAZ associated protein 2 1.50849679E-08 1.23270364E-07 -1.7472 2.6016 2.4941 2.3466 2.7663 3.8148 2.720790576 ZNF799 zinc finger protein 799 0.0012076742 0.003298941992 -1.7476 1.5847 1.1489 1.3547 1.6745 1.3525 1.875051131 PHF11 PHD finger protein 11 9.64816622E-07 5.03545539E-06 -1.7477 1.8068 2.7863 2.0340 1.7545 2.6009 2.00583386 ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 0.00659585486 0.014997443994 -1.7477 1.2903 1.6789 1.5092 0.4590 0.7148 1.0102100289019 LOC100289019 uncharacterized LOC100289019 0.00169028349 0.004458619888 -1.7486 0.2480 0.5757 0.4318 0.1284 0.1194 0.356393349 SP140L SP140 nuclear body protein-like 2.67973243E-07 1.59856582E-06 -1.7487 1.2476 1.5861 0.9846 1.1873 1.5825 1.0990135458 HUS1B HUS1 checkpoint homolog b (S. pombe) 0.01240631815 0.026080101848 -1.7501 0.1757 0.3487 0.2730 0.1680 0.2891 0.1901285989 ZNF789 zinc finger protein 789 0.00236049797 0.006018001812 -1.7511 1.0990 1.0699 0.8334 1.1622 1.7074 1.32068812 CCNK cyclin K 7.71635197E-09 6.7850425E-08 -1.7519 7.1633 4.5851 2.6039 4.9717 4.6140 2.1397285362 SUMF1 sulfatase modifying factor 1 1.65386647E-06 8.23193901E-06 -1.7536 2.1225 2.0156 1.2545 1.4692 2.7873 1.6035375743 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2.34216327E-08 1.81982041E-07 -1.7556 2.5223 2.7803 1.7320 2.7638 3.7608 2.4954129293 TRABD2A TraB domain containing 2A 4.83651377E-07 2.70501315E-06 -1.7571 2.3606 2.2887 1.9173 2.2125 2.2241 2.132357472 CNOT6 CCR4-NOT transcription complex, subunit 6 1.0624344E-09 1.23412596E-08 -1.7582 1.7773 2.7823 2.1834 1.5476 3.3080 1.94318535 CBX4 chromobox homolog 4 4.79524849E-09 4.55635884E-08 -1.7590 1.1661 3.7304 1.4895 1.6222 4.4817 1.92576296 ACSM3 acyl-CoA synthetase medium-chain family member 3 0.00189429052 0.004934066494 -1.7594 1.0211 0.7595 1.4352 1.0676 0.9406 1.1503123811 FOPNL FGFR1OP N-terminal like,FGFR1OP N-terminal like 2.41118773E-07 1.4564371E-06 -1.7596 1.6773 1.4162 1.8207 1.6090 1.4212 1.59329535 GMFG glia maturation factor, gamma 3.16143813E-06 1.4754993E-05 -1.7600 1.8068 2.7743 1.7392 1.7218 3.7070 2.26832069 EREG epiregulin 0.02604768959 0.049551627718 -1.7612 1.3429 0.6717 1.1874 0.7096 0.5378 0.7029401588 ZNF674-AS1 ZNF674 antisense RNA 1 (head to head) 0.0022238865 0.005702337101 -1.7626 1.8090 9.1405 2.5734 0.5323 4.7123 1.235364105 CENPK centromere protein K 0.0004122741 0.001241442364 -1.7629 1.3552 2.4245 2.1233 0.3540 0.4454 1.285054916 TMEM260 transmembrane protein 260 0.00030795916 0.000954704752 -1.7633 1.1766 0.7712 0.9861 1.1090 1.3765 1.31801739 DLG1 discs, large homolog 1 (Drosophila) 4.53329944E-11 8.68264647E-10 -1.7647 0.6144 0.5741 0.5474 0.5746 0.4285 0.41957404 UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.00022095053 0.000703959577 -1.7647 0.6734 0.6808 0.4313 0.6488 0.2820 0.533354932 EXD3 exonuclease 3'-5' domain containing 3 0.00129406554 0.003509226108 -1.7650 0.6730 0.3924 1.4798 0.5806 0.1127 1.6067440944 SETD5-AS1 SETD5 antisense RNA 1 3.25650748E-06 1.51561143E-05 -1.7683 2.6185 1.6225 2.8123 2.3599 1.6428 3.83724299 AFF1 AF4/FMR2 family, member 1 2.78688462E-06 1.31649317E-05 -1.7684 2.6383 4.4482 2.4999 2.1912 4.6291 3.183480342 TRAF3IP3 TRAF3 interacting protein 3 8.95348679E-05 0.000310963905 -1.7704 3.0149 2.1853 2.4700 2.3588 1.9111 2.11529906 SLC35E2 solute carrier family 35, member E2 2.86165341E-07 1.69656493E-06 -1.7704 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970653268 AGAP7 centaurin, gamma-like family, member 4 0.00033285991 0.001023756017 -1.7711 0.1393 0.1318 0.2222 0.3849 0.1248 0.132656967 C14orf132 chromosome 14 open reading frame 132 0.00193686838 0.00503707075 -1.7715 1.7831 1.5074 1.7595 1.1334 0.8558 1.5111474170 LRRC37A2 leucine rich repeat containing 37, member A2 9.38125944E-08 6.25599899E-07 -1.7721 0.1822 0.1998 0.2438 0.2896 0.1703 0.238979858 NEK11 NIMA-related kinase 11 0.00734967421 0.016473656431 -1.7725 1.5198 0.1088 0.4751 0.4371 0.0858 0.31997335 UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.00017398429 0.000566472023 -1.7725 2.6194 2.4374 2.3520 2.1296 2.3270 2.42727695 ZNF136 zinc finger protein 136 8.98116286E-05 0.000311763528 -1.7726 2.2463 1.4807 1.5759 1.8560 1.8149 1.48372287 FKBP3 FK506 binding protein 3, 25kDa 5.02705562E-08 3.58665991E-07 -1.7726 2.3062 1.9748 1.4085 2.5634 2.6729 2.7341126068 ZNF441 zinc finger protein 441 0.00152215873 0.004061460922 -1.7729 1.4713 1.6961 2.4408 1.4293 1.8245 2.725510892 MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 2.81242078E-07 1.67117244E-06 -1.7730 1.8091 1.8962 2.3877 1.4311 1.7383 2.257655680 RUFY2 RUN and FYVE domain containing 2 0.00192612046 0.005011972793 -1.7760 0.8662 1.3392 0.8839 1.0504 1.5853 1.12926041 RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 0.00102039757 0.002828383556 -1.7761 2.0243 1.8117 1.1356 2.0113 1.6524 1.029879090 TRAPPC6A trafficking protein particle complex 6A 4.20311784E-05 0.000155527277 -1.7765 1.3007 3.7835 3.9864 0.9773 5.1785 3.113684657 LINC00852 long intergenic non-protein coding RNA 852 0.00055699789 0.001627873544 -1.7790 0.6943 0.8852 1.4092 0.5551 0.3784 0.6215

RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene

mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)

N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

124446 TMEM219 transmembrane protein 219 2.80973902E-07 1.6701526E-06 -1.7804 0.7054 0.9758 1.0371 0.6542 0.8249 0.8751

83860 TAF3 1.91541617E-07 1.18800014E-06 -1.7816 2.1097 1.2576 2.0173 1.8478 2.7083 2.54169884 LRRC37A leucine rich repeat containing 37A 1.5337564E-07 9.72745469E-07 -1.7819 0.2359 0.2406 0.2790 0.3460 0.2804 0.3203100289230 LOC100289230 uncharacterized LOC100289230 0.00231246016 0.005907070052 -1.7820 1.4006 1.8356 1.1462 1.7912 3.9658 3.1104642475 MROH6 maestro heat-like repeat family member 6 0.00208504558 0.005387915821 -1.7832 0.7433 2.4011 0.8501 0.6737 0.5558 0.49059572 NR1D1 nuclear receptor subfamily 1, group D, member 1 3.47057532E-05 0.000130401711 -1.7850 1.4277 2.4102 2.3392 1.0794 2.0009 1.554764753 CCDC136 coiled-coil domain containing 136 0.00211337437 0.00545417748 -1.7852 0.3094 0.4484 0.5121 0.3171 0.2990 0.5755339487 ZBTB8OS zinc finger and BTB domain containing 8 opposite strand 4.95557839E-09 4.68528355E-08 -1.7854 2.9381 2.4469 1.5896 2.3472 3.3283 2.30199665 KIAA0430 KIAA0430 6.86060794E-09 6.1691451E-08 -1.7857 3.3577 2.5548 4.0808 1.7337 1.1629 5.308725939 SAMHD1 SAM domain and HD domain 1 4.40908248E-05 0.000162588809 -1.7883 1.1957 1.2463 1.2904 1.3363 1.3364 1.4274440515 ZNF506 zinc finger protein 506 2.31557854E-08 1.80273758E-07 -1.7889 1.8335 3.3732 1.7746 2.3244 6.2460 2.9038253782 CERS6 LAG1 homolog, ceramide synthase 6 (S. cerevisiae) 3.92866612E-08 2.88175782E-07 -1.7891 1.1734 1.0719 1.9921 1.0861 1.8111 2.629728962 OSTM1 osteopetrosis associated transmembrane protein 1 5.43495092E-06 2.41918205E-05 -1.7899 1.4059 3.3692 2.0902 1.4655 3.4301 2.565754843 SYTL2 synaptotagmin-like 2 0.00070430246 0.002014876249 -1.7899 0.7598 0.5594 0.7601 0.6591 0.5010 0.56385534 PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 2.40697731E-05 9.30996811E-05 -1.7903 2.6082 4.9676 1.8542 2.8365 7.3790 3.004387 ACTN1 actinin, alpha 1 0.00018236258 0.000591012613 -1.7923 0.6997 0.5868 0.8063 0.6415 0.4396 0.795611064 CNTRL centriolin 5.30177312E-08 3.7577191E-07 -1.7926 0.9471 1.0110 0.7131 0.9339 1.0024 0.64807844 RNF103 ring finger protein 103 1.33231605E-08 1.10403985E-07 -1.7933 0.9171 0.9820 0.9480 0.9868 1.0949 1.330055779 WDR52 WD repeat domain 52 0.00489825056 0.011555950196 -1.7939 0.1586 0.0865 0.2016 0.1894 0.1270 0.2269100528018 ARL2-SNX15 ARL2-SNX15 readthrough (NMD candidate) 7.08501929E-06 3.07499935E-05 -1.7942 1.2956 0.7651 0.8487 0.9619 0.6988 0.6488201158 TVP23C family with sequence similarity 18, member B2 7.04470863E-05 0.000249943526 -1.7950 0.3321 0.3321 0.3321 0.3970 0.3970 0.397051652 CHMP3 charged multivesicular body protein 3 0.00097992108 0.002728606836 -1.7960 2.1003 1.3755 1.4672 2.3446 1.8921 2.09415727 PTCH1 patched 1 0.00036306378 0.001105650218 -1.7981 0.9868 1.7019 0.9516 0.8811 1.5059 1.04606659 SOX4 SRY (sex determining region Y)-box 4 0.0005332735 0.001566303384 -1.7984 1.8024 1.2368 1.8973 1.3417 0.8666 1.301055859 BEX1 brain expressed, X-linked 1 0.00128229174 0.003481431608 -1.7989 0.4023 0.5791 0.4793 0.3027 0.2399 0.5536

200576 PIKFYVE 2.88072357E-10 4.11544809E-09 -1.7994 2.2161 2.9617 2.1095 2.2782 3.4905 2.57746853 SYN1 synapsin I 0.02267099116 0.043965649599 -1.7996 0.6665 1.0537 0.9848 0.7715 0.4620 0.848523446 SLC44A1 solute carrier family 44 (choline transporter), member 1 0.00040968745 0.00123487447 -1.7999 1.2475 2.7253 0.8799 0.9373 2.2384 0.9324728404 AGAP8 centaurin, gamma-like family, member 5 0.00010890672 0.000371258116 -1.8006 0.1564 0.1494 0.3786 0.3670 0.1583 0.28909960 USP3 ubiquitin specific peptidase 3 5.83289234E-09 5.36379511E-08 -1.8024 1.3676 1.5850 0.6644 1.3350 2.0741 0.99293769 KCNJ13 potassium inwardly-rectifying channel, subfamily J, member 13 0.00664284967 0.015083652191 -1.8039 0.4120 0.1314 0.3064 0.3260 0.1042 0.16916128 RPL6 ribosomal protein L6 7.58426987E-10 9.25098658E-09 -1.8049 2.1030 1.2235 1.7266 2.2425 1.8973 2.064557547 ZNF624 zinc finger protein 624 0.00176520367 0.004630840122 -1.8052 1.5652 2.0913 1.1636 1.5308 2.6092 1.595783641 FAM107B family with sequence similarity 107, member B 0.0001106239 0.000376620068 -1.8060 1.7672 1.8352 1.0311 1.6198 1.7284 1.008627332 ZNF638 zinc finger protein 638 2.48929793E-10 3.61274439E-09 -1.8063 0.8011 0.9559 0.9235 0.8058 1.1482 1.088110026 PIGK phosphatidylinositol glycan anchor biosynthesis, class K 4.60659694E-06 2.07728873E-05 -1.8066 3.1951 2.3716 1.5741 2.4636 3.4268 2.053865979 PHACTR4 phosphatase and actin regulator 4 1.13008625E-07 7.39045668E-07 -1.8068 1.3525 1.4333 1.5482 1.2639 1.7066 1.4744140545 RNF32 ring finger protein 32 0.00135033168 0.003645037733 -1.8104 0.1807 0.1533 0.6940 0.4712 0.1861 0.3233729092 AGAP5 centaurin, gamma-like family, member 2 0.00077159741 0.002193656126 -1.8104 0.1853 0.1985 0.2292 0.4948 0.2147 0.282984288 EFCAB2 EF-hand calcium binding domain 2 0.00340574819 0.008351876375 -1.8105 1.1643 1.8038 1.5634 1.3754 2.1871 2.8861

256435 ST6GALNAC3 0.0087207184 0.019167008909 -1.8107 1.1717 1.9012 2.0299 1.1121 1.5528 1.924023421 ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 1.01710096E-07 6.71404216E-07 -1.8109 2.9654 0.8004 1.1890 1.2491 0.5033 0.823057493 HEG1 heart development protein with EGF-like domains 1 0.00045810466 0.001363049721 -1.8109 1.8994 1.6850 1.4456 1.4274 1.3969 1.306023586 DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00301794543 0.007505634795 -1.8113 2.0221 1.4558 1.1414 2.0571 1.7244 1.05756792 CDKL5 cyclin-dependent kinase-like 5 0.00310628197 0.007702264097 -1.8114 0.6236 1.0396 0.6721 0.4130 1.3398 0.801911059 WWP1 WW domain containing E3 ubiquitin protein ligase 1 3.93158174E-09 3.83135262E-08 -1.8129 1.2891 1.0630 0.7277 1.4623 2.2065 0.912984181 CHD6 chromodomain helicase DNA binding protein 6 3.77601693E-11 7.49949797E-10 -1.8141 0.5636 0.3745 0.6768 0.5746 0.4313 0.765526260 FBXO25 F-box protein 25 6.67983534E-08 4.63027129E-07 -1.8145 0.7889 1.0691 0.7770 0.6369 1.4287 0.810551372 TMA7 translation machinery associated 7 homolog (S. cerevisiae) 7.35885515E-09 6.52406605E-08 -1.8150 1.1645 1.4425 2.6174 0.3853 1.4419 1.9291171392 ZNF675 zinc finger protein 675 1.03209752E-05 4.32335762E-05 -1.8153 3.4304 1.6089 0.8049 3.6954 2.7210 2.0071254128 LOC254128 hypothetical protein LOC254128 0.00151122037 0.004036400901 -1.8155 2.8247 2.8322 2.3902 2.1849 2.7380 3.659156890 MDM1 Mdm1 nuclear protein homolog (mouse) 4.46421315E-05 0.000164489015 -1.8181 1.7664 2.9199 2.0889 1.4152 2.9396 2.07745504 PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 7.03591769E-09 6.28349404E-08 -1.8183 1.5551 2.1830 1.3918 2.6331 3.2433 2.349422877 MLXIP MLX interacting protein 1.30115586E-07 8.36548907E-07 -1.8191 0.5076 0.6859 0.5438 0.4909 0.8729 0.685925875 LETMD1 LETM1 domain containing 1 1.76937595E-07 1.10454518E-06 -1.8191 1.9964 2.9440 2.0486 1.7183 3.5999 1.882484056 KATNAL1 katanin p60 subunit A-like 1 0.00024020974 0.000761337807 -1.8196 0.9078 2.0727 1.2916 1.4557 1.8368 1.79329556 C14orf2 chromosome 14 open reading frame 2 6.16967751E-09 5.63661737E-08 -1.8200 2.0775 1.7818 2.1166 1.9662 2.7625 2.4359246777 SPESP1 sperm equatorial segment protein 1 0.01051367934 0.022566186879 -1.8201 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970199746 U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 2.1532962E-05 8.42866926E-05 -1.8209 1.6319 4.5304 2.7014 1.6028 2.5176 1.9797199704 ZNF585A zinc finger protein 585A 0.00102832847 0.002848638248 -1.8213 2.3404 1.7488 1.4691 2.0566 1.5135 1.8730259282 BOD1L1 family with sequence similarity 44, member A 8.55577352E-10 1.02445016E-08 -1.8217 3.4712 1.4319 1.4648 1.3418 1.1680 0.7952114825 PWWP2A PWWP domain containing 2A 5.87703417E-10 7.46767513E-09 -1.8220 1.2678 1.6996 0.8942 1.4291 2.0069 1.588079629 OCEL1 occludin/ELL domain containing 1 1.99709917E-05 7.86783009E-05 -1.8221 1.6015 1.7627 1.5328 1.5197 1.7319 2.05737913 DEK DEK oncogene 7.45736113E-09 6.60498801E-08 -1.8223 2.2859 2.4131 1.4622 2.1211 2.7927 1.7916

727758 ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.00102827797 0.002848638248 -1.8236 0.0388 0.0324 0.1201 0.2757 0.0782 0.2264221322 TBC1D32 chromosome 6 open reading frame 170 0.00154906642 0.004126356317 -1.8261 1.0260 0.9307 0.8486 1.3954 1.0078 0.914726520 TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 1.972874E-06 9.64117513E-06 -1.8262 2.3601 0.6724 2.3991 1.9784 0.6224 0.864023515 MORC3 MORC family CW-type zinc finger 3 1.42117737E-07 9.0764603E-07 -1.8262 2.1124 1.9090 1.9441 2.2551 2.2497 2.467457544 TXNDC16 thioredoxin domain containing 16 0.00042260513 0.001267537893 -1.8264 3.2146 2.6625 2.5053 1.8241 1.3741 3.2207374986 FAM73A family with sequence similarity 73, member A 3.88700602E-05 0.000145034458 -1.8269 0.7443 0.7914 0.8206 0.6799 0.6969 0.804725981 DNAH1 dynein, axonemal, heavy chain 1 9.69787871E-06 4.08482342E-05 -1.8269 0.2922 0.3882 0.4349 0.2606 0.4254 0.297779441 HAUS3 HAUS augmin-like complex, subunit 3 1.52725753E-08 1.24469445E-07 -1.8285 3.6691 1.0129 0.2998 1.9787 0.8609 0.120251735 RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 1.30567856E-09 1.48182352E-08 -1.8291 1.0520 1.0027 0.6986 1.2821 1.4273 1.026454491 FAM105A family with sequence similarity 105, member A 3.20286209E-05 0.000120914661 -1.8297 1.4467 1.6408 1.2575 1.3700 2.5548 1.685184343 HPS3 Hermansky-Pudlak syndrome 3 1.79983088E-07 1.12202354E-06 -1.8300 1.1127 1.7223 0.8968 1.0578 2.1326 1.226951310 SLC22A17 solute carrier family 22, member 17 0.00068804924 0.0019702297 -1.8302 0.7856 1.6378 1.2730 0.7761 1.1741 1.214154894 RNF43 ring finger protein 43 0.0016475569 0.004359131152 -1.8302 0.4085 0.3945 0.6735 0.2683 0.1416 0.5090654434 LINC00338 long intergenic non-protein coding RNA 338 0.0011431351 0.003139679196 -1.8306 0.5583 0.3547 1.0737 0.5076 0.1598 0.4513286148 DPY19L4 dpy-19-like 4 (C. elegans) 0.00015608698 0.000513600085 -1.8308 1.2256 1.3695 1.4476 0.9234 2.5237 1.72499788 MTSS1 metastasis suppressor 1 9.1443674E-05 0.000316570445 -1.8337 0.9120 1.0244 0.7828 0.6554 0.7428 0.6373285830 HLA-F-AS1 hypothetical protein FLJ35429 0.00158465794 0.004209780451 -1.8350 0.5307 0.5479 0.5920 0.5657 0.6050 0.603557711 ZNF529 zinc finger protein 529 6.83683862E-06 2.97435036E-05 -1.8352 1.0766 1.6460 1.3667 1.1363 2.1569 1.539057162 PELI1 pellino E3 ubiquitin protein ligase 1 2.44406575E-07 1.47434696E-06 -1.8353 0.8916 0.8685 0.5862 0.8826 0.8607 0.6595196951 FAM227B family with sequence similarity 227, member B 0.0018776604 0.004895635107 -1.8360 0.9143 0.4431 0.3588 1.2650 0.2306 0.459055755 CDK5RAP2 CDK5 regulatory subunit associated protein 2 1.15999946E-08 9.74058366E-08 -1.8361 0.6287 0.3988 0.7053 0.6754 0.3180 0.6134143884 CWF19L2 CWF19-like 2, cell cycle control (S. pombe) 1.69064848E-08 1.36042921E-07 -1.8361 1.3626 1.6742 1.1323 1.5763 1.5247 1.2062

7534 YWHAZ 1.25217603E-10 2.00348165E-09 -1.8362 2.0960 2.2034 1.7140 1.9847 3.4951 2.595855900 ZNF302 zinc finger protein 302 1.46166365E-05 5.92447166E-05 -1.8364 1.8806 3.0594 1.7943 2.5948 4.1306 2.60516988 TCTA T-cell leukemia translocation altered 6.26383634E-07 3.41854294E-06 -1.8369 0.6320 16.0711 4.3395 1.3364 13.1629 2.7072746 TMEM258 transmembrane protein 258 1.24965379E-07 8.07985637E-07 -1.8373 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

10565 ARFGEF1 1.70308688E-09 1.85562335E-08 -1.8379 0.7161 0.4315 0.4952 0.7780 0.5497 0.721283744 ZNF484 zinc finger protein 484 0.00016308459 0.000534028972 -1.8405 2.5467 2.0852 1.2457 2.8244 2.3306 2.26027403 KDM6A lysine (K)-specific demethylase 6A 1.95947013E-10 2.92272965E-09 -1.8409 0.8590 1.3543 0.7346 1.5125 2.5833 2.2361

80024 SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 1.15323397E-06 5.9307321E-06 -1.8414 1.2971 1.3899 0.8917 1.6837 1.7886 0.917557606 SLAIN2 SLAIN motif family, member 2 5.7217686E-10 7.3021991E-09 -1.8417 1.1571 1.2737 1.0097 1.0009 1.7207 1.577522901 ARSG arylsulfatase G 0.00036383782 0.001107822802 -1.8424 3.4053 3.0886 2.3947 2.6906 2.6552 1.629354737 MPHOSPH8 M-phase phosphoprotein 8 1.08835465E-07 7.14567594E-07 -1.8466 1.0747 0.8424 0.9558 1.3731 1.5450 1.242251585 PCF11 PCF11 cleavage and polyadenylation factor subunit 1.24316423E-10 1.99605421E-09 -1.8466 2.0752 1.3860 1.5740 3.1800 2.9264 3.7263643253 CCT6P1 chaperonin containing TCP1, subunit 6A (zeta 1) pseudogene 1 0.00025370345 0.000800633749 -1.8466 4.6523 1.7727 1.5661 1.8564 0.5961 1.511623508 TTC9 tetratricopeptide repeat domain 9 4.72079072E-09 4.50199833E-08 -1.8473 2.3396 3.6754 1.5233 2.0694 3.6604 2.119081688 C6orf62 chromosome 6 open reading frame 62 1.32444769E-09 1.49960577E-08 -1.8483 3.5355 3.0261 2.1356 2.3634 3.0864 2.1314950 SCARB2 scavenger receptor class B, member 2 0.00649367922 0.014799339046 -1.8486 2.1140 1.1466 1.2130 1.2928 0.4692 0.978557730 ANKRD36B KIAA1641 7.83924186E-06 3.37111384E-05 -1.8493 0.7897 0.7074 0.6939 0.9990 1.3417 1.181154103 GSAP gamma-secretase activating protein 0.01438733846 0.029657654369 -1.8502 0.8617 0.4532 1.0202 0.7019 0.3372 0.939023041 MON2 MON2 homolog (S. cerevisiae) 6.40683758E-12 1.85815878E-10 -1.8509 1.0212 0.7044 0.7118 1.1408 0.9032 0.91197267 TTC3 tetratricopeptide repeat domain 3 1.71157244E-09 1.8626475E-08 -1.8512 0.9709 14.2491 1.1186 1.5265 11.5733 1.1578162427 FAM134C family with sequence similarity 134, member C 1.77055792E-07 1.10490555E-06 -1.8512 0.4077 1.2806 1.4159 0.2550 0.8442 0.809351542 VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 3.82144159E-08 2.80874419E-07 -1.8553 1.0480 1.2603 0.7109 0.9279 1.7314 0.7063

118924 FRA10AC1 4.91790362E-07 2.74297726E-06 -1.8554 1.6353 1.3851 1.4477 1.4472 1.9153 1.675094134 ARHGAP12 Rho GTPase activating protein 12 1.05412996E-05 4.40454211E-05 -1.8558 1.2943 1.1833 0.9174 1.2695 1.7667 1.0837285973 ATG9B ATG9 autophagy related 9 homolog B (S. cerevisiae) 0.00038614443 0.001169894054 -1.8560 0.1108 0.1417 0.5212 0.2001 0.0613 0.28255252 PHF1 PHD finger protein 1 6.44610511E-06 2.82047971E-05 -1.8565 1.0840 1.8931 1.3887 1.0300 1.4649 1.619827146 FAM184B family with sequence similarity 184, member B 0.00168496686 0.004445879355 -1.8574 0.4721 1.0270 0.8225 0.5159 1.0907 0.5320115209 OMA1 OMA1 zinc metallopeptidase 0.00104119647 0.002879482652 -1.8575 0.2769 0.2581 0.2577 0.3423 0.2504 0.28608644 AKR1C3 aldo-keto reductase family 1, member C3 0.01822247698 0.036405105994 -1.8578 0.6341 0.5939 0.3285 0.6178 0.5020 0.31415864 RAB3A RAB3A, member RAS oncogene family 0.00076922964 0.002187945817 -1.8584 1.7817 1.9415 2.2080 1.3250 2.2039 2.71025495 PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 5.46397342E-12 1.64317521E-10 -1.8585 1.5114 1.7084 1.3969 2.1423 2.6340 4.421855791 LRIF1 ligand dependent nuclear receptor interacting factor 1 6.78291667E-06 2.9537048E-05 -1.8589 0.9661 1.1090 0.9730 1.4213 1.0506 1.344710800 CYSLTR1 cysteinyl leukotriene receptor 1 0.00869765925 0.019122082751 -1.8590 2.2291 2.9692 1.6396 2.4932 2.3449 1.371351390 AIG1 androgen-induced 1 0.00015148295 0.000499710514 -1.8598 1.6520 1.3057 1.6445 1.3805 1.2391 1.57092027 ENO3 enolase 3 (beta, muscle) 0.00144786441 0.003881933746 -1.8617 0.4667 0.8455 0.9888 0.2960 0.7236 0.70374154 MBNL1 muscleblind-like splicing regulator 1 2.83636504E-10 4.05842302E-09 -1.8630 2.0092 1.9778 1.8183 1.4780 1.4610 1.0929151516 ASPRV1 skin aspartic protease 0.0011712719 0.00320861772 -1.8652 0.1685 0.1404 0.1930 0.2725 0.0305 0.18809743 ARHGAP32 Rho GTPase activating protein 32 1.11435769E-05 4.63078091E-05 -1.8654 0.2848 0.3123 0.1943 0.2741 0.1674 0.204454764 ZRANB1 zinc finger, RAN-binding domain containing 1 6.97077807E-09 6.24363024E-08 -1.8672 0.8677 1.1354 0.3448 0.4707 0.5737 0.2480359948 IRF2BP2 interferon regulatory factor 2 binding protein 2 1.40024586E-06 7.06971328E-06 -1.8672 2.4569 3.0124 1.4860 2.0586 3.3599 3.141864167 ERAP2 endoplasmic reticulum aminopeptidase 2 2.64046995E-08 2.02038148E-07 -1.8673 1.9857 1.4235 1.6086 1.7984 1.2148 1.23579668 ZNF432 zinc finger protein 432 0.00093864011 0.00262445785 -1.8675 2.4096 2.5800 1.7629 2.8578 3.8648 2.2513

10106 CTDSP2 1.43731901E-08 1.18034575E-07 -1.8694 0.8703 1.1183 0.8615 0.9175 1.4892 1.32011649 DDIT3 DNA-damage-inducible transcript 3 0.00033404432 0.001027205946 -1.8706 2.4119 3.3331 2.4773 2.0121 3.6713 3.01933920 LAMP2 lysosomal-associated membrane protein 2 6.05150714E-08 4.23489615E-07 -1.8707 1.8217 2.3878 1.2400 1.7457 3.1873 1.91331859 DYRK1A E2F transcription factor 1 1.39876039E-09 1.56414625E-08 -1.8715 0.9054 0.8812 0.8405 1.1088 1.1053 1.5481130026 ICA1L islet cell autoantigen 1,69kDa-like 0.00102142208 0.002830793911 -1.8728 0.7329 1.0634 0.5989 0.9168 1.2111 0.803610748 KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 0.02397548619 0.04620123219 -1.8737 0.0931 0.0631 0.0544 0.1027 0.0201 0.109325949 SYF2 SYF2 pre-mRNA-splicing factor 6.79124872E-08 4.69858753E-07 -1.8741 2.3139 1.9397 1.6358 2.3195 2.9914 2.1903

TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa

phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)

fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

915 CD3D CD3d molecule, delta (CD3-TCR complex) 1.15063976E-08 9.6753289E-08 -1.8749 3.8458 3.0464 2.6989 3.3567 4.6450 3.156411119 BTN3A1 butyrophilin, subfamily 3, member A1 2.0021078E-06 9.76577813E-06 -1.8758 3.6934 2.2806 1.6358 4.6665 2.5784 1.88919098 USP6 ubiquitin specific peptidase 6 (Tre-2 oncogene) 0.00115509287 0.003168571819 -1.8763 0.2227 0.4700 0.1971 0.1693 0.0858 0.255651186 WBP5 WW domain binding protein 5 0.00137374636 0.003700043249 -1.8765 2.2655 2.3422 2.0372 1.9214 2.7937 1.409155013 CCDC109B coiled-coil domain containing 109B 7.06994171E-10 8.71085468E-09 -1.8766 1.6919 2.0825 2.2701 1.6869 2.2127 3.377851227 PIGP phosphatidylinositol glycan anchor biosynthesis, class P 4.47903258E-05 0.000165001781 -1.8776 1.2408 1.8879 3.7195 0.5851 1.0104 1.98176155 RPL27 ribosomal protein L27 9.64321598E-09 8.26902362E-08 -1.8788 2.0498 1.7431 2.0289 1.6852 3.1121 2.045579848 CSPP1 centrosome and spindle pole associated protein 1 3.95965703E-05 0.000147506492 -1.8792 0.7991 0.8647 0.8654 0.6827 0.7765 0.831280232 WDR26 WD repeat domain 26 1.60484511E-09 1.76224338E-08 -1.8796 1.4547 1.7621 2.2579 1.4774 2.7625 3.392084216 TMEM117 transmembrane protein 117 0.00094362176 0.002636772731 -1.8799 1.5925 1.6448 1.5494 1.4444 1.5788 1.606384661 DPY30 dpy-30 homolog (C. elegans) 4.7289374E-09 4.50741493E-08 -1.8806 0.3804 0.0966 0.9908 0.3253 0.1169 1.51306342 SCP2 sterol carrier protein 2 4.24461072E-10 5.65787017E-09 -1.8811 2.7099 3.4670 1.0943 1.7887 2.5773 0.852084851 TRIM52 tripartite motif containing 52 1.26767096E-05 5.20631239E-05 -1.8819 2.8993 2.8814 2.4005 2.8422 2.4131 2.134310241 CALCOCO2 calcium binding and coiled-coil domain 2 8.35161201E-09 7.2736251E-08 -1.8824 1.7588 2.0495 1.6961 1.7078 2.3823 1.87937673 ZNF222 zinc finger protein 222 0.00132954069 0.00359528895 -1.8830 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970203328 SUSD3 sushi domain containing 3 2.98453407E-06 1.40080674E-05 -1.8835 1.0448 0.7515 0.9555 0.9129 1.2890 1.02326446 SGK1 serum/glucocorticoid regulated kinase 1 0.012297193 0.025880478055 -1.8838 1.9700 1.5803 1.4757 1.6912 1.5947 1.51868287 USP9Y ubiquitin specific peptidase 9, Y-linked 8.08586422E-06 3.46574973E-05 -1.8844 0.4150 0.4300 0.1778 0.9150 0.3557 0.279927258 LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 4.95012506E-08 3.54006595E-07 -1.8846 0.3698 3.8349 2.4189 3.8657 2.2791 7.1895400322 HERC2P2 hect domain and RLD 2 pseudogene 2 1.21683946E-05 5.01898208E-05 -1.8848 0.7347 0.5550 0.7563 0.7234 0.4900 0.9905402483 LINC01000 long intergenic non-protein coding RNA 1000 7.66119093E-07 4.09433404E-06 -1.8850 0.0291 0.0327 0.2351 0.1457 0.0848 0.144357053 CHRNA10 cholinergic receptor, nicotinic, alpha 10 0.00171942736 0.004524391809 -1.8850 0.0239 0.0678 0.2060 0.2014 0.0135 0.240927067 STAU2 staufen double-stranded RNA binding protein 2 2.01909881E-11 4.57729199E-10 -1.8853 0.8239 1.0784 0.8332 0.8424 1.4348 0.9638118491 TTC18 tetratricopeptide repeat domain 18 0.01318119043 0.027487641121 -1.8865 0.5787 0.3989 0.4897 0.6079 0.3430 0.49046337 SCNN1A sodium channel, non-voltage-gated 1 alpha subunit 0.02073990576 0.040743958506 -1.8876 1.8543 1.7416 1.2094 1.3226 1.1569 1.013710251 SPRY3 sprouty homolog 3 (Drosophila) 0.00660684986 0.015016838 -1.8887 1.9959 1.3130 1.2841 1.6648 1.2390 1.27505939 RBMS2 RNA binding motif, single stranded interacting protein 2 0.00118236293 0.003236089786 -1.8890 1.5701 1.2809 1.5516 1.0158 1.3213 1.06917148 TNXB tenascin XB 0.00410774863 0.00988369541 -1.8892 0.3152 0.3558 0.3142 0.3714 0.3874 0.345851265 CDKL3 cyclin-dependent kinase-like 3 0.00100818308 0.002797922426 -1.8903 2.1973 2.3826 1.2097 1.0675 2.5975 1.08898603 FAM193A family with sequence similarity 193, member A 6.69144952E-12 1.91339852E-10 -1.8922 0.1335 0.1554 0.2762 0.2115 0.1449 0.265126469 PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 5.71457963E-08 4.01294385E-07 -1.8932 1.9414 1.7892 2.0005 1.4760 2.6587 2.35439669 EIF5B eukaryotic translation initiation factor 5B 6.97275505E-06 3.03018904E-05 -1.8933 0.9104 1.1235 0.8901 0.8926 1.9821 1.45853575 IL7R interleukin 7 receptor 0.00044965991 0.001339886794 -1.8933 2.7274 3.0323 2.1242 3.4191 4.8098 1.457911168 PSIP1 PC4 and SFRS1 interacting protein 1 1.16709807E-09 1.34120855E-08 -1.8950 4.0422 3.7131 1.6888 2.9984 3.9126 1.77106234 RPS28 ribosomal protein S28 1.61799706E-08 1.31144495E-07 -1.8957 0.5979 6.5895 3.3451 0.3184 5.8428 2.026479872 CBLL1 Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 5.4118697E-08 3.82093057E-07 -1.8960 3.0219 2.4629 1.7022 3.4380 3.3105 2.521191404 SESTD1 SEC14 and spectrin domains 1 0.00077475105 0.00220125192 -1.8981 0.9174 0.6126 1.2116 0.9510 0.5102 0.964822931 RAB18 RAB18, member RAS oncogene family 8.17079748E-12 2.22831062E-10 -1.8981 1.9605 1.2624 2.0201 1.5377 1.5507 2.4613100132403 FAM157B family with sequence similarity 157, member B 0.00221975827 0.005693349689 -1.8984 0.0866 0.2750 0.1271 0.2517 0.1657 0.229765056 GPBP1 GC-rich promoter binding protein 1 1.53749857E-09 1.69849903E-08 -1.8985 1.2399 1.1081 0.8426 1.3596 1.1424 1.179793589 CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.00099639778 0.002768579707 -1.8986 0.2347 0.5319 0.2596 0.3372 0.2259 0.2681

51054 PLEKHA8P1 0.00120726068 0.003298305495 -1.8991 1.2638 1.5487 1.1057 0.7201 1.0734 4.677623390 ZDHHC17 zinc finger, DHHC-type containing 17 1.40372831E-09 1.56874151E-08 -1.8998 1.6971 1.8178 1.3622 1.6036 2.3576 2.0437145173 B3GALTL beta 1,3-galactosyltransferase-like 0.00027672431 0.000865657697 -1.9001 0.7366 0.8081 0.7069 0.8703 0.6874 1.0512667 DST dystonin 0.00192876296 0.005018134242 -1.9001 0.4077 0.3957 0.6620 0.3520 0.3810 0.41053988 LIPA lipase A, lysosomal acid, cholesterol esterase 1.2180902E-07 7.89533314E-07 -1.9024 2.1027 17.7663 1.3580 1.1797 4.4203 1.306923033 DOPEY1 dopey family member 1 1.66764469E-06 8.28697408E-06 -1.9030 0.5522 0.6977 0.4601 0.6467 0.6663 0.625654879 ST7L suppression of tumorigenicity 7 like 0.00053466171 0.001569623829 -1.9047 1.1823 0.9534 0.7713 1.0192 0.7949 0.64168559 PRPF18 pre-mRNA processing factor 18 2.90806498E-11 6.12167781E-10 -1.9053 1.7250 1.8443 1.3712 1.9343 2.0439 1.575711215 AKAP11 A kinase (PRKA) anchor protein 11 6.82514231E-10 8.46439166E-09 -1.9055 2.0525 3.2562 1.6704 2.2787 2.8858 2.314723348 DOCK9 dedicator of cytokinesis 9 3.1920925E-08 2.38356821E-07 -1.9062 0.6580 0.6575 0.6650 0.6364 0.5773 0.67271427 CRYGS crystallin, gamma S 0.02520310878 0.048185749051 -1.9067 0.0645 0.1669 0.0888 0.0909 0.0536 0.157257551 TAOK1 TAO kinase 1 2.30347696E-10 3.37523104E-09 -1.9074 1.9017 2.4591 0.9513 0.6927 3.9301 0.52954621 MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 0.00058056668 0.001691344779 -1.9082 0.0273 0.0203 0.1347 0.1376 0.1432 0.265863940 GPSM3 G-protein signaling modulator 3 6.59736523E-08 4.57657774E-07 -1.9087 0.5968 0.5858 0.6039 0.6197 0.6048 0.69665799 PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00049249922 0.001457083174 -1.9131 0.4360 0.5522 0.2612 0.6788 0.4936 0.226164746 ACBD3 acyl-Coenzyme A binding domain containing 3 1.87596118E-09 2.01395785E-08 -1.9135 1.5704 2.1956 1.8754 1.2355 3.2450 2.3026388272 C16orf87 similar to RIKEN cDNA 4921524J17 1.73150964E-05 6.91393009E-05 -1.9157 1.7599 2.9930 1.5453 1.6149 3.9669 2.938657111 RAB25 RAB25, member RAS oncogene family 0.00951662501 0.02070747326 -1.9159 0.1758 0.1829 0.2601 0.3730 0.1702 0.2841388228 SBK1 SH3-binding domain kinase 1 9.58402766E-05 0.000330538606 -1.9160 1.8385 1.8966 3.0625 1.5971 2.1098 2.609923215 PRRC2C proline-rich coiled-coil 2C 7.93680289E-11 1.36426399E-09 -1.9175 0.6662 0.7400 0.6081 0.8406 1.0550 0.94858204 NRIP1 nuclear receptor interacting protein 1 1.4160766E-06 7.13977694E-06 -1.9184 2.2302 2.3354 2.3583 2.3894 2.5971 2.976651246 SHISA5 shisa family member 5 1.29200038E-07 8.31540364E-07 -1.9201 1.3818 1.1678 1.6884 0.9940 0.7549 1.184657186 RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 4.18101665E-08 3.04850503E-07 -1.9202 0.8250 0.9222 0.7838 0.8721 1.0490 0.992311221 DUSP10 dual specificity phosphatase 10 1.75294433E-05 6.99035331E-05 -1.9216 1.3985 1.4931 1.5078 1.6049 1.9559 1.9807152006 RNF38 ring finger protein 38 8.53431604E-13 3.84086263E-11 -1.9233 1.5812 1.4832 1.7964 1.3585 1.8528 2.132051317 PHF21A PHD finger protein 21A 4.90700763E-10 6.38748157E-09 -1.9240 0.8826 1.5169 0.7006 1.0438 2.3703 1.417855608 ANKRD10 ankyrin repeat domain 10 6.71552606E-08 4.65324582E-07 -1.9242 1.1120 1.3703 0.7954 1.2825 1.8866 1.965351201 ZDHHC2 zinc finger, DHHC-type containing 2 4.90211579E-07 2.73746086E-06 -1.9244 1.9637 1.4808 1.7833 1.3121 2.4726 2.42377569 ZNF182 zinc finger protein 182 0.00010782494 0.00036798231 -1.9254 1.9433 16.3538 0.7476 0.6597 16.8088 0.62533600 IL15 interleukin 15 0.00132495249 0.003585111902 -1.9265 2.0800 1.3900 2.2662 2.2600 1.3827 2.0932256051 ZNF549 zinc finger protein 549 0.00013374971 0.000446696149 -1.9269 1.7042 2.5527 1.4722 2.0101 2.1616 1.41696197 RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 7.78284252E-10 9.4553257E-09 -1.9280 1.2206 2.0791 1.0381 1.1535 3.0946 1.141627250 PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.85902466E-05 7.37314927E-05 -1.9284 1.3989 3.0890 0.7875 2.7066 4.2481 2.51389087 TMSB4Y thymosin beta 4, Y-linked 0.01642480353 0.0332589094 -1.9284 1.7737 2.1008 0.7140 1.5107 2.0150 1.0731135114 HINT3 histidine triad nucleotide binding protein 3 1.38799648E-07 8.88628999E-07 -1.9285 1.5814 1.7079 1.9900 1.7326 1.7679 1.87205204 PFDN5 prefoldin subunit 5 1.14737385E-09 1.32270126E-08 -1.9286 1.6324 2.2338 1.6786 1.5858 3.3736 1.97395775 PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 6.87214461E-09 6.17647941E-08 -1.9287 1.4845 1.1118 0.9103 1.2487 1.0016 1.04762256 FGF11 fibroblast growth factor 11 0.01243740488 0.026124412222 -1.9297 0.8310 1.6625 1.8289 0.6196 1.0584 1.521126273 FBXO3 F-box protein 3 1.30670467E-08 1.08379972E-07 -1.9299 1.3069 1.3478 0.9929 1.1714 1.2382 1.0545145389 SLC38A6 solute carrier family 38, member 6 0.00087714819 0.002468389311 -1.9301 1.3262 0.6707 1.9289 1.4622 0.4417 1.124910010 TANK TRAF family member-associated NFKB activator 9.41540642E-09 8.10549615E-08 -1.9313 3.2287 2.5350 1.7319 3.0293 2.5947 1.728598 ACYP2 acylphosphatase 2, muscle type 0.00090008532 0.00252787565 -1.9313 1.4006 2.0533 1.4146 1.6637 2.2166 1.7148163486 DENND1B DENN/MADD domain containing 1B 3.29669858E-09 3.27732734E-08 -1.9321 1.1673 1.1218 1.1549 0.9423 0.7200 0.870564778 FNDC3B fibronectin type III domain containing 3B 5.47464897E-05 0.000198163205 -1.9323 0.8173 1.2301 0.8159 0.7110 0.8949 0.970781606 LBH limb bud and heart development 7.15445249E-06 3.10145091E-05 -1.9344 1.5704 2.3312 2.3536 1.9560 3.0964 3.3035133874 C5orf58 hypothetical gene LOC133874 0.00118625368 0.003246252385 -1.9354 0.0271 0.1138 0.1316 0.1546 0.0371 0.1415143244 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 8.76591385E-06 3.72837006E-05 -1.9356 0.0285 0.0292 0.0794 0.3709 0.0234 0.15409988 DMTF1 cyclin D binding myb-like transcription factor 1 2.57427034E-11 5.57972332E-10 -1.9361 0.9644 0.7982 0.6596 1.0721 1.0439 0.814784441 MAML2 mastermind-like 2 (Drosophila) 1.15958583E-07 7.55633105E-07 -1.9386 2.5589 1.7470 1.3825 3.3157 2.8563 1.8754100533464 PRH1-PRR4 PRH1-PRR4 readthrough 0.00059008366 0.001715514501 -1.9392 7.7983 3.6343 1.8311 7.1359 3.7987 1.360255303 GIMAP4 Q9NUV9,G5E9W9,GTPase, IMAP family member 4 0.00020322125 0.000652823262 -1.9395 2.5018 1.8684 2.0122 2.8463 2.0951 2.622050640 PNPLA8 patatin-like phospholipase domain containing 8 2.17885361E-08 1.71087293E-07 -1.9396 0.7075 0.8623 0.6228 0.7848 0.8342 0.89337181 NR2C1 nuclear receptor subfamily 2, group C, member 1 9.55035638E-07 4.99153638E-06 -1.9397 0.5733 0.7143 0.6316 0.6685 0.9409 0.972511238 CA5B carbonic anhydrase VB, mitochondrial 0.00116573447 0.003194885292 -1.9399 2.3785 2.8220 2.0830 2.5871 1.8653 1.7598100130890 TSTD3 thiosulfate sulfurtransferase (rhodanese)-like domain containing 3 0.00516560064 0.012108512497 -1.9415 0.7030 1.0793 0.7992 0.7549 1.2836 1.147851592 TRIM33 tripartite motif containing 33 2.00911852E-11 4.56350388E-10 -1.9425 0.6096 0.7668 0.5846 0.7813 1.2877 0.9842150678 MYEOV2 myeloma overexpressed 2 2.12119599E-10 3.14598158E-09 -1.9427 1.8130 2.8446 1.6934 1.6439 3.3813 1.9398100133161 LINC01001 long intergenic non-protein coding RNA 1001 2.95918659E-05 0.000112582718 -1.9449 0.0422 0.0654 0.1596 0.1437 0.0707 0.223756605 ERO1LB ERO1-like beta (S. cerevisiae) 0.00030051631 0.000934485028 -1.9454 1.5986 1.9349 2.1162 1.4852 2.9148 2.396023261 CAMTA1 calmodulin binding transcription activator 1 5.4039061E-09 5.03406061E-08 -1.9454 0.4524 1.1750 0.5477 0.5948 1.5822 0.8861280 AMY2B amylase, alpha 2B (pancreatic) 0.00092556846 0.002591875398 -1.9456 0.1470 0.1471 0.1674 0.4064 0.0815 0.0933130916 MTERFD2 MTERF domain containing 2 1.74344363E-07 1.09021909E-06 -1.9467 1.9016 1.8920 1.5879 1.7283 2.1625 1.91078832 CD84 CD84 molecule 8.44581077E-05 0.000295239821 -1.9496 2.6297 2.4958 1.9484 2.0930 2.1358 1.42332074 ERCC6 excision repair cross-complementation group 6 2.78565412E-06 1.31625219E-05 -1.9498 0.1304 0.1799 0.2377 0.1808 0.2123 0.19729360 PPIG peptidylprolyl isomerase G (cyclophilin G) 5.97598877E-09 5.47609161E-08 -1.9546 1.2691 0.6918 0.4535 1.4259 1.5655 0.97065305 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 6.49603638E-10 8.12662095E-09 -1.9560 0.8165 1.2531 0.6746 0.8932 1.2061 1.03796263 RYR3 ryanodine receptor 3 0.0261491068 0.04972902575 -1.9560 0.4551 0.7378 0.5117 0.3131 0.5297 0.62026920 TCEA3 transcription elongation factor A (SII), 3 0.0011449139 0.00314395353 -1.9577 0.7166 0.8032 0.7903 0.7658 1.1971 0.8757146330 FBXL16 F-box and leucine-rich repeat protein 16 1.60096893E-05 6.43911606E-05 -1.9626 1.2287 1.7117 1.2656 0.5570 1.3766 1.3301100133991 MAP3K14-AS1 MAP3K14 antisense RNA 1 0.00043061732 0.001288818957 -1.9640 1.0504 1.6413 2.2958 0.7422 1.9161 1.4245814 CAMK4 calcium/calmodulin-dependent protein kinase IV 5.04315163E-08 3.59533619E-07 -1.9642 0.9433 1.5526 0.9610 1.1620 1.8003 1.098910477 UBE2E3 ubiquitin-conjugating enzyme E2E 3 1.11733845E-10 1.82285786E-09 -1.9651 2.1984 2.7544 1.2294 1.9080 2.2887 1.490954462 CCSER2 coiled-coil serine-rich protein 2 4.3073389E-09 4.14012079E-08 -1.9660 1.3360 1.1584 0.7030 1.1389 0.9736 0.73729402 GRAP2 GRB2-related adaptor protein 2 0.00027101834 0.00085028283 -1.9662 2.8521 2.5120 2.1476 2.0102 2.1261 1.693780205 CHD9 chromodomain helicase DNA binding protein 9 2.04086601E-08 1.61361764E-07 -1.9664 0.7253 0.6556 0.7915 0.4871 0.5258 0.605151176 LEF1 lymphoid enhancer-binding factor 1 8.24874292E-06 3.52894008E-05 -1.9673 2.7282 2.0194 1.6376 2.5464 2.1190 1.778210000 AKT3 v-akt murine thymoma viral oncogene homolog 3 2.52849794E-09 2.59846538E-08 -1.9674 0.5607 1.0173 0.7073 0.5948 0.7321 0.296590673 PPP1R3E protein phosphatase 1, regulatory subunit 3E 0.00317334883 0.007845140021 -1.9713 1.6422 1.7949 2.7407 1.3757 1.8957 3.135551125 GOLGA7 golgin A7 9.67593902E-12 2.53293349E-10 -1.9728 1.5627 1.5025 1.9041 1.4645 2.0760 1.857180146 UXS1 UDP-glucuronate decarboxylase 1 1.73355016E-07 1.08514657E-06 -1.9744 1.6659 2.3388 1.4725 1.1423 2.2197 1.33617360 UGP2 UDP-glucose pyrophosphorylase 2 6.2143931E-11 1.12425139E-09 -1.9757 1.8906 1.9212 1.6458 2.0299 2.4155 2.27509874 TLK1 tousled-like kinase 1 6.64887468E-10 8.28705581E-09 -1.9774 0.5526 0.8589 0.4071 0.7152 1.2362 0.7868284454 LOC284454 hypothetical protein LOC284454 0.00017120014 0.000558202878 -1.9781 0.8284 1.3200 1.9205 0.3748 1.1019 1.239079725 THAP9 THAP domain containing 9 0.00043198339 0.001292484111 -1.9782 1.2745 2.6561 1.1090 0.7402 1.6868 0.786855592 GOLGA2P5 golgin A2 pseudogene 5 0.00071284132 0.002037709096 -1.9799 0.0491 0.0546 0.1388 0.2004 0.0235 0.2120115703 ARHGAP33 Rho GTPase activating protein 33 0.00076180836 0.00216818728 -1.9811 0.6633 0.3940 0.7225 0.4384 0.4413 0.6172143686 SESN3 sestrin 3 0.00141216888 0.00379366197 -1.9820 2.4232 2.5696 2.0198 2.1290 1.9307 2.413579958 DENND1C DENN/MADD domain containing 1C 2.063013E-09 2.17640725E-08 -1.9826 1.1881 1.6178 1.8221 0.9706 1.3171 1.8720663 BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 1.53136338E-10 2.37062502E-09 -1.9834 2.3411 1.3833 1.6784 2.4252 1.6766 2.49788661 EIF3A eukaryotic translation initiation factor 3, subunit A 1.31377831E-10 2.06942735E-09 -1.9848 1.2339 1.2037 0.9076 1.3856 2.6936 1.64389827 RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) 8.40619697E-09 7.31071066E-08 -1.9849 0.3321 0.3321 0.3321 0.3970 0.3970 0.397054828 BCAS3 breast carcinoma amplified sequence 3 0.00011797649 0.000399345379 -1.9858 0.4995 0.4380 0.5306 0.6196 0.3891 0.61391486 CTBS chitobiase, di-N-acetyl- 2.05842125E-05 8.09022867E-05 -1.9860 2.4728 1.7881 2.0846 2.7105 1.6529 2.69559448 MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 5.81424529E-09 5.34933988E-08 -1.9864 0.7712 0.5956 0.5325 0.7066 0.6808 0.527828971 AAMDC adipogenesis associated, Mth938 domain containing 0.0008294033 0.002344864152 -1.9879 29.3560 1.8851 0.4165 9.3297 0.6277 0.2950196500 PIANP PILR alpha associated neural protein 0.01247008734 0.026184030788 -1.9885 1.1165 3.0641 1.2322 0.6843 2.6304 0.94965555 PRH2 proline-rich protein HaeIII subfamily 2 0.00305831397 0.007597758374 -1.9891 0.1533 0.0292 0.1267 0.3319 0.0243 0.2196686 BTD biotinidase 0.00027457137 0.000860649876 -1.9915 0.9261 1.3128 1.1833 2.1960 3.0811 0.7434130355 C2orf76 hypothetical protein LOC130355 0.00061317323 0.001776423209 -1.9924 1.4743 5.2263 3.1443 0.7637 2.3169 1.888429125 C11orf21 chromosome 11 open reading frame 21 8.21496894E-05 0.000287886292 -1.9942 3.5489 6.9855 2.4809 2.5918 3.2056 1.07281657 DMXL1 Dmx-like 1 5.20511104E-11 9.7229495E-10 -1.9956 1.2204 1.1767 0.6923 0.9311 1.0711 0.924323473 CAPN7 calpain 7 5.74723291E-13 2.96648135E-11 -1.9965 2.3377 3.4472 1.7616 2.0510 5.7565 2.2265

pleckstrin homology domain containing, family A member 8 pseudogene 1

64393 ZMAT3 zinc finger, matrin-type 3 7.21487278E-07 3.88764835E-06 -1.9983 2.4954 1.0771 1.6786 2.2111 1.2299 2.15734090 SMAD5 SMAD family member 5 2.55496735E-06 1.21700635E-05 -2.0015 2.3059 0.9000 2.1809 1.9746 0.8417 2.534254469 ZFAND6 zinc finger, AN1-type domain 6 1.47747513E-11 3.55688357E-10 -2.0021 2.7105 2.0630 0.9989 1.8136 1.9171 1.1830285740 LOC285740 hypothetical protein LOC285740 0.01510276734 0.030950848465 -2.0036 0.2509 0.1810 0.3976 0.3380 0.3648 0.250184837 ARHGAP5-AS1 chromosome 14 open reading frame 128 0.00683925458 0.015486913184 -2.0038 2.7882 2.0524 1.9239 2.0064 0.9796 0.77581002 CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.02631230152 0.049971767323 -2.0041 0.1269 0.0866 0.1859 0.2431 0.0351 0.22749108 MTMR7 myotubularin related protein 7 0.00044694993 0.001332898493 -2.0042 0.1884 0.4238 0.2588 0.2546 0.3875 0.318285464 SSH2 slingshot protein phosphatase 2 1.91665495E-10 2.86823254E-09 -2.0044 2.3144 3.9483 1.1888 2.2243 4.3540 1.5560148213 ZNF681 zinc finger protein 681 0.00027767613 0.000868486508 -2.0048 1.0323 1.3404 0.8041 1.0603 1.1477 1.1660400073 C12orf76 FLJ40142 protein 8.7378311E-05 0.000304283686 -2.0050 1.4622 1.1249 1.2822 1.3359 1.1341 1.310222887 FOXJ3 forkhead box J3 6.78496441E-09 6.12221578E-08 -2.0092 2.1341 3.1632 1.8155 2.0107 4.8799 2.6396493861 EID3 EP300 interacting inhibitor of differentiation 3 9.68664003E-05 0.000333762562 -2.0095 1.7928 1.5802 1.8111 1.4515 0.9730 0.9411147837 ZNF563 zinc finger protein 563 0.00047166712 0.001399529339 -2.0102 1.6713 1.7959 1.7006 1.7785 2.1342 2.15594063 LY9 lymphocyte antigen 9 0.00198299516 0.005143851146 -2.0123 2.2954 1.1709 1.8737 1.9990 0.9297 0.919126118 WSB1 WD repeat and SOCS box containing 1 1.74866671E-05 6.97634022E-05 -2.0139 1.7464 6.4419 1.9355 2.3552 7.5602 3.7204

1604 CD55 7.68263955E-07 4.1045962E-06 -2.0143 2.1035 1.8732 1.9282 2.1478 2.2450 1.95217122 CLDN5 claudin 5 0.02204399729 0.042895411974 -2.0155 0.5941 0.9203 0.5413 0.5536 0.3293 0.476657459 GATAD2B GATA zinc finger domain containing 2B 1.06527332E-09 1.23585233E-08 -2.0163 2.4797 2.7522 1.7539 2.2302 5.5743 2.85724600 MX2 myxovirus (influenza virus) resistance 2 (mouse) 0.00990332708 0.021449826245 -2.0164 1.1017 1.2424 0.9052 1.0334 1.1264 0.663664853 AIDA chromosome 1 open reading frame 80 3.35335547E-11 6.8080568E-10 -2.0199 1.0145 8.4754 1.4825 0.7353 5.5591 0.532310157 AASS aminoadipate-semialdehyde synthase 0.00041580901 0.001251261904 -2.0204 1.3906 1.2723 0.9272 1.2207 1.6293 1.07366135 RPL11 ribosomal protein L11 3.0648099E-10 4.31434565E-09 -2.0224 1.6559 1.5267 2.1760 1.2029 3.0156 2.47077561 ZNF14 zinc finger protein 14 5.16981094E-06 2.31016839E-05 -2.0229 1.8297 2.6052 1.8047 2.1372 3.2121 2.69034815 NINJ2 ninjurin 2 0.00018359267 0.000594893659 -2.0236 1.4834 1.6777 1.7262 1.3755 1.4294 1.0944339894 LINC00880 long intergenic non-protein coding RNA 880 0.01752010662 0.035198173529 -2.0237 0.1274 0.2363 0.5399 0.3225 0.0571 0.323530011 SH3KBP1 SH3-domain kinase binding protein 1 7.09855032E-11 1.25318562E-09 -2.0262 1.3179 1.3690 1.5256 1.1870 1.1881 1.3118

10210 TOPORS 5.86748766E-10 7.46073309E-09 -2.0273 0.8564 0.8667 1.3585 0.6141 0.3060 0.627056900 TMEM167B transmembrane protein 167B 1.95788586E-08 1.55473665E-07 -2.0282 3.0284 3.0215 1.9350 2.7747 5.5809 3.30339786 KIAA0586 KIAA0586 2.11426271E-09 2.22149559E-08 -2.0285 0.8668 0.6033 0.6619 0.5402 0.6624 0.399510018 BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.00010564353 0.000361212304 -2.0326 2.4969 2.8563 1.8952 2.0730 3.5039 2.2215824 CAPN2 calpain 2, (m/II) large subunit 6.81367137E-08 4.71231655E-07 -2.0334 1.3507 0.8796 0.9482 1.1973 0.9804 0.730223411 SIRT1 sirtuin 1 2.45355381E-07 1.47860604E-06 -2.0335 1.1958 1.1453 0.7740 1.3110 0.9398 0.922257104 PNPLA2 patatin-like phospholipase domain containing 2 1.97798838E-08 1.56865467E-07 -2.0351 0.7353 0.4747 0.6351 0.3884 0.5437 0.6483728190 NUTM2A-AS1 NUTM2A antisense RNA 1 6.31366065E-11 1.13469197E-09 -2.0352 2.8047 2.4316 5.0703 2.1464 0.8572 2.5209266812 NAP1L5 nucleosome assembly protein 1-like 5 0.00024582054 0.000777652724 -2.0354 1.5037 2.8479 0.9917 1.8785 2.7971 1.425757658 CALCOCO1 calcium binding and coiled-coil domain 1 1.76778582E-05 7.04646215E-05 -2.0364 1.2727 1.0387 1.0210 1.2000 1.2261 1.2437400954 EML6 echinoderm microtubule associated protein like 6 0.0051678605 0.012111623969 -2.0409 1.2428 0.8050 1.2271 0.8833 0.5444 1.010855333 SYNJ2BP P57105,synaptojanin 2 binding protein 0.00012338973 0.000415973652 -2.0410 0.3321 0.3321 0.3321 0.3970 0.3970 0.397084436 ZNF528 zinc finger protein 528 0.00038494772 0.001166461821 -2.0426 0.6834 0.7766 0.9266 1.2109 0.7017 0.896825873 RPL36 ribosomal protein L36 4.06887486E-10 5.4601056E-09 -2.0428 1.2706 1.3224 1.3602 1.4924 2.7429 2.2148120227 CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 8.03916313E-08 5.4667506E-07 -2.0430 1.2571 2.0070 1.3020 1.1180 1.3695 1.26699910 RABGAP1L RAB GTPase activating protein 1-like 2.32165973E-08 1.80670215E-07 -2.0435 1.1078 0.8451 1.0053 0.9683 0.7938 0.923851014 TMED7 transmembrane emp24 protein transport domain containing 7 2.27441502E-07 1.38112699E-06 -2.0443 2.5060 2.8504 1.6365 1.0951 1.5533 1.2494360023 ZBTB41 zinc finger and BTB domain containing 41 4.25082112E-06 1.92923506E-05 -2.0465 2.1399 2.1446 1.1885 1.1978 1.3979 0.6491400927 LOC400927 TPTE and PTEN homologous inositol lipid phosphatase pseudogene 0.00136104821 0.003670711875 -2.0471 1.5278 1.1543 1.5535 0.9315 1.1714 0.931923524 SRRM2 serine/arginine repetitive matrix 2 1.82748432E-11 4.23216647E-10 -2.0474 16.3237 3.3624 0.4211 11.6244 7.5109 0.69087423 VEGFB vascular endothelial growth factor B 1.71326947E-07 1.07429169E-06 -2.0487 0.9664 1.0236 1.6867 0.8199 1.2250 1.58513587 IL10RA interleukin 10 receptor, alpha 0.0001713905 0.000558624185 -2.0493 1.9567 2.1505 2.1783 2.3043 1.7496 2.9247440482 ANKRD20A5P similar to ankyrin repeat domain 20A 0.00034976327 0.001069368104 -2.0501 0.9213 0.8440 1.0195 0.8351 0.7419 1.020285012 TCEAL3 transcription elongation factor A (SII)-like 3 0.00025316448 0.000799070891 -2.0509 1.6285 0.5791 1.2009 1.3638 0.8351 1.15445837 PYGM phosphorylase, glycogen, muscle 0.00135263038 0.003649625274 -2.0530 1.2594 0.4447 0.7871 0.6693 0.2550 0.29576430 SRSF5 serine/arginine-rich splicing factor 5 5.06648474E-08 3.60915435E-07 -2.0534 0.9679 0.7548 0.9876 0.5992 0.4384 0.69473151 HMGN2 high mobility group nucleosomal binding domain 2 1.1522722E-07 7.51403201E-07 -2.0535 1.3603 2.5625 1.6338 1.1884 2.5979 2.430757786 RBAK RB-associated KRAB zinc finger 2.15761647E-10 3.18448854E-09 -2.0535 3.0367 5.5144 1.5804 2.7837 2.3067 1.017257209 ZNF248 zinc finger protein 248 7.69290482E-05 0.000271255803 -2.0541 2.3169 1.4385 1.5246 2.2486 1.8228 1.8983400761 FLJ27354 uncharacterized LOC400761 0.00027478855 0.00086092872 -2.0552 2.1064 0.8313 0.4262 1.1071 0.4556 0.3361100287227 TIPARP-AS1 TIPARP antisense RNA 1 0.00067944416 0.001947725711 -2.0554 0.3321 0.3321 0.3321 0.3970 0.3970 0.397055062 WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00049916358 0.001474651077 -2.0614 1.5012 1.2569 2.2690 1.0318 1.5954 2.09826156 RPL30 ribosomal protein L30 1.13434961E-09 1.30851238E-08 -2.0617 2.6799 2.8130 2.2973 2.8099 4.8239 3.49311850 DUSP8 dual specificity phosphatase 9 0.00037927118 0.001150596551 -2.0622 2.2150 3.2335 1.4187 1.6921 2.1883 0.852911143 KAT7 K(lysine) acetyltransferase 7 5.55939519E-12 1.6652667E-10 -2.0626 1.9369 1.4022 1.1552 1.0121 0.6456 0.6807539 ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 8.28175372E-11 1.41292441E-09 -2.0629 2.0878 2.2323 1.7436 1.8298 2.9195 1.634629799 YPEL1 yippee-like 1 (Drosophila) 0.00055078407 0.001611517469 -2.0640 2.7560 2.1710 2.3205 1.4686 0.8484 2.22428869 ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.00159031029 0.00422356826 -2.0640 1.2409 1.5293 1.4481 1.1166 1.0608 1.2253202020 TAPT1-AS1 hypothetical FLJ39653 0.00042393509 0.001271318225 -2.0641 1.1057 6.6133 3.4438 0.3934 5.6920 3.25619585 KIF20B kinesin family member 20B 4.19151018E-09 4.05009381E-08 -2.0649 0.6299 1.2304 0.6630 0.6182 1.7377 0.98049254 CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00037208899 0.001130309246 -2.0652 0.8044 1.2762 0.9116 0.5383 1.0007 0.598210207 INADL InaD-like (Drosophila) 1.73730031E-09 1.88503274E-08 -2.0653 0.3724 0.3274 0.5302 0.3603 0.4641 0.52438519 IFITM1 interferon induced transmembrane protein 1 1.35955898E-05 5.55249478E-05 -2.0655 2.3770 3.7258 3.1836 2.2394 5.0086 4.712251065 RPS27L ribosomal protein S27-like 2.82921362E-08 2.14650481E-07 -2.0658 1.7495 1.8397 1.5758 2.1382 2.1781 2.54579666 DZIP3 DAZ interacting zinc finger protein 3 2.38417766E-05 9.22764123E-05 -2.0659 1.1840 1.0398 0.7436 0.9414 0.6440 0.302779026 AHNAK AHNAK nucleoprotein 0.00036186778 0.001102375463 -2.0675 1.2889 2.3028 1.7886 1.2910 1.9983 2.47485016 OVGP1 oviductal glycoprotein 1, 120kDa 0.01099768975 0.023469958781 -2.0676 0.2120 0.2834 0.2835 0.4115 0.0290 0.25909205 ZMYM5 zinc finger, MYM-type 5 1.3795898E-06 6.98278804E-06 -2.0697 1.1099 1.2124 1.0987 1.2456 2.1301 2.298011273 ATXN2L ataxin 2-like 1.60162066E-10 2.46336808E-09 -2.0698 0.9703 1.7464 1.1494 0.8803 1.6726 1.21167994 KAT6A K(lysine) acetyltransferase 6A 4.48817338E-11 8.62820387E-10 -2.0714 1.0912 3.4872 1.3532 1.4132 4.0981 1.788610693 CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 0.00066184754 0.001902655486 -2.0724 0.4763 1.4549 0.4564 0.0458 1.5737 0.339027086 FOXP1 forkhead box P1 3.11535355E-08 2.33198443E-07 -2.0776 2.0928 1.7917 1.4815 1.9227 1.8825 1.33939633 MTL5 metallothionein-like 5, testis-specific (tesmin) 0.00032082589 0.000990894283 -2.0793 0.9373 1.4541 1.0899 0.7379 1.0844 1.22686125 RPL5 ribosomal protein L5 7.1446931E-10 8.79109981E-09 -2.0797 1.7293 1.8898 1.3552 1.4358 2.1543 1.23091911 PHC1 polyhomeotic homolog 2 (Drosophila) 1.01780618E-07 6.71432576E-07 -2.0799 1.7524 1.7830 2.0780 1.5814 1.9703 1.3267388692 LOC388692 uncharacterized LOC388692 1.46799876E-05 5.94619227E-05 -2.0816 1.2277 0.7655 1.2225 0.7539 0.5215 0.679665250 C5orf42 hypothetical protein FLJ13231 8.96528103E-06 3.80431061E-05 -2.0822 0.4050 0.4626 0.3413 0.4844 0.3683 0.3728339829 CCDC39 coiled-coil domain containing 39 0.00524420118 0.012264436715 -2.0833 1.2300 0.7536 1.0383 1.1474 0.8539 0.78612803 GOLGA4 golgin A4 1.2143177E-08 1.01454106E-07 -2.0840 1.1265 1.1474 0.9533 1.3957 1.8907 1.511355167 MSL2 male-specific lethal 2 homolog (Drosophila) 2.91413947E-08 2.20029572E-07 -2.0848 2.3809 3.1371 1.6816 2.7314 3.8971 3.10263140 MR1 major histocompatibility complex, class I-related 5.96413351E-06 2.62784296E-05 -2.0849 2.0717 3.1684 1.9203 1.8371 2.9184 1.4553594 BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 7.9360649E-08 5.40066212E-07 -2.0863 1.5018 1.2384 1.5708 1.5823 1.6425 2.29653476 IGBP1 immunoglobulin (CD79A) binding protein 1 3.76531936E-10 5.13432205E-09 -2.0871 2.2544 3.6936 2.3124 2.4219 5.4064 3.067990488 C12orf23 chromosome 12 open reading frame 23 9.88945422E-11 1.64123622E-09 -2.0871 0.9452 1.0510 0.6682 0.9770 1.4501 1.075151444 RNF138 ring finger protein 138, E3 ubiquitin protein ligase 1.14952166E-07 7.50144994E-07 -2.0872 1.8022 2.1984 1.2789 2.1859 3.6699 1.7237337875 HIST2H2BA histone cluster 2, H2ba (pseudogene) 0.00011495403 0.000389764344 -2.0894 1.3870 1.2235 0.7782 1.3842 1.0580 0.803623258 DENND5A DENN/MADD domain containing 5A 5.39739526E-06 2.40422248E-05 -2.0918 1.6510 1.1270 0.9493 1.3412 0.9768 1.157085459 KIAA1731 KIAA1731 7.25133622E-10 8.90437208E-09 -2.0926 0.6406 0.6395 0.6397 0.8625 0.7360 0.77355588 PRKCQ protein kinase C, theta 4.82440636E-09 4.57692384E-08 -2.0935 1.1488 0.4613 1.4535 1.2578 0.3450 1.8441652968 GATSL3 GATS protein-like 3 7.6043346E-05 0.000268339903 -2.0939 1.1889 1.2538 0.7774 0.8313 1.0824 0.73758452 CUL3 cullin 3 3.86527343E-09 3.77882698E-08 -2.0945 1.6387 2.2934 1.0077 1.2729 1.5795 1.4710201283 AMZ2P1 hypothetical protein FLJ32065 0.00027561467 0.00086307304 -2.0947 1.5616 1.8947 2.4311 1.0976 1.7019 1.969584060 RBM48 RNA binding motif protein 48 1.24469243E-06 6.35617257E-06 -2.0966 0.8818 2.8333 0.7404 0.3851 0.1994 0.2736113263 GLCCI1 glucocorticoid induced transcript 1 1.62246362E-06 8.093272E-06 -2.0969 2.2374 3.6395 1.7243 1.9945 3.3710 2.32938935 SKAP2 src kinase associated phosphoprotein 2 0.00026323296 0.000829131648 -2.0974 0.8535 1.7543 0.7600 0.8203 1.3863 0.9934150864 FAM117B family with sequence similarity 117, member B 3.99002728E-06 1.8212785E-05 -2.0996 1.5149 5.5589 1.8665 1.9590 9.9586 3.0151192286 HIGD2A HIG1 hypoxia inducible domain family, member 2A 2.84924979E-09 2.88749264E-08 -2.1007 3.8590 3.3044 0.3249 1.4986 0.9310 2.9052100505783 OSER1-AS1 OSER1 antisense RNA 1 (head to head) 0.00036988809 0.001124371188 -2.1014 2.0131 2.3500 1.4321 1.2053 0.5913 0.9528284370 ZNF615 zinc finger protein 615 2.28248424E-05 8.89054617E-05 -2.1017 1.9662 2.5731 1.6872 2.8275 3.4740 2.29839321 TRIP11 thyroid hormone receptor interactor 11 7.31539395E-12 2.05325466E-10 -2.1020 1.3611 1.6523 0.9967 1.4937 2.3233 1.29839467 SH3BP5 SH3-domain binding protein 5 (BTK-associated) 1.52871079E-05 6.17158718E-05 -2.1029 0.9542 0.9442 0.8295 1.2221 0.8380 0.70096189 RPS3A ribosomal protein S3A 7.58938838E-11 1.31818731E-09 -2.1039 2.8732 3.3052 1.6952 3.2078 4.5552 1.89107041 TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.0102926657 0.022174900332 -2.1046 0.4375 0.5921 0.7560 0.5980 0.3700 0.7820373 TRIM23 tripartite motif containing 23 9.52220348E-08 6.34304419E-07 -2.1058 2.7128 3.7979 3.4021 1.5131 3.5509 2.697179015 LOC79015 uncharacterized LOC79015 0.01925190574 0.038186150858 -2.1064 1.9773 1.1659 1.3138 1.3830 0.4735 0.7873387856 C12orf68 similar to expressed sequence AI836003 0.00690492416 0.01561083571 -2.1076 2.2063 1.9004 1.9173 1.6288 1.8026 2.2623400685 LOC400685 uncharacterized LOC400685 0.00114242293 0.003138528322 -2.1098 0.0575 0.0053 0.0881 0.1224 0.0122 0.13918450 CUL4B cullin 4B 2.46565473E-11 5.37618655E-10 -2.1102 1.2063 0.9340 0.9375 1.3784 0.6864 1.405479640 C22orf46 hypothetical protein FLJ23584 1.37441358E-05 5.60564394E-05 -2.1119 0.2283 0.5531 0.4685 0.1119 0.2319 0.203457149 LYRM1 LYR motif containing 1 1.95635033E-08 1.55419275E-07 -2.1145 2.5674 6.6932 3.2839 1.6646 4.2927 2.59163094 HINT1 histidine triad nucleotide binding protein 1 4.33668392E-11 8.37630957E-10 -2.1147 1.7037 1.8630 2.2661 1.5265 1.9456 2.6692100133331 LOC100133331 uncharacterized LOC100133331 4.03834375E-06 1.84062909E-05 -2.1155 0.0486 0.0883 0.1279 0.1563 0.0315 0.1770400027 LINC00938 long intergenic non-protein coding RNA 938 2.44080678E-07 1.47286729E-06 -2.1165 2.5397 2.4840 1.5289 2.9906 3.9961 2.440394039 ZNF101 zinc finger protein 101 4.31443472E-06 1.95567728E-05 -2.1170 1.7462 2.6289 1.5650 2.1370 2.9681 3.049455870 ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 1.16579235E-12 4.84693833E-11 -2.1178 2.4393 3.7154 1.4601 3.8192 11.2473 2.8517135295 SRSF12 serine/arginine-rich splicing factor 12 0.00127190573 0.00345682902 -2.1186 1.9878 1.6439 1.4396 1.5030 1.9761 1.200822900 CARD8 caspase recruitment domain family, member 8 3.96863983E-09 3.86262394E-08 -2.1200 1.1244 1.2008 0.8110 0.7108 1.2450 0.64461520 CTSS cathepsin S 0.00200921239 0.005207422533 -2.1220 2.2598 1.2973 1.3006 2.6059 1.5220 1.0625284058 KANSL1 KIAA1267 7.42681505E-12 2.0686397E-10 -2.1246 0.8772 1.2228 0.8194 0.9546 1.6838 1.2178441150 C6orf226 similar to RIKEN cDNA 2310039H08 3.01573552E-05 0.000114512717 -2.1249 1.7987 1.6363 1.9314 1.7728 2.5922 1.99628073 PTP4A2 protein tyrosine phosphatase type IVA, member 2 3.02506205E-11 6.29543665E-10 -2.1260 1.1552 1.2919 1.1745 1.3965 1.4146 1.253951193 ZNF639 zinc finger protein 639 5.83702997E-11 1.06975137E-09 -2.1267 1.8175 2.0131 1.9790 1.7478 2.6074 2.129928232 SLCO3A1 solute carrier organic anion transporter family, member 3A1 1.87138273E-05 7.41733301E-05 -2.1274 1.7512 1.5695 1.4933 1.1166 0.9406 1.6145100302692 FTX FTX transcript, XIST regulator (non-protein coding) 9.06874968E-08 6.07197487E-07 -2.1276 1.9124 2.2220 2.0450 2.4634 4.0312 2.74857151 topoisomerase (DNA) I pseudogene 1 0.00044579144 0.00133009491 -2.1281 0.0496 0.0415 0.1873 0.1345 0.0875 0.1595

10396 ATP8A1 1.57331878E-05 6.34046773E-05 -2.1282 1.3013 1.2207 0.9121 1.5923 1.4268 1.66499720 CCDC144A coiled-coil domain containing 144A 0.00030251556 0.000939582577 -2.1291 0.2450 0.3038 0.3880 0.2502 0.1693 0.4483100505715 LOC100505715 uncharacterized LOC100505715 0.01647450715 0.033332419571 -2.1295 1.8843 2.6761 1.6308 1.8803 2.2612 1.495611127 KIF3A kinesin family member 3A 9.85762965E-08 6.53788054E-07 -2.1319 0.5029 0.6150 0.6989 0.5126 0.4942 0.6916731275 LOC731275 uncharacterized LOC731275 2.52619137E-05 9.73809468E-05 -2.1330 0.7985 0.6074 0.9205 1.0064 0.3365 1.2985100125288 ZGLP1 zinc finger, GATA-like protein 1 0.00121022934 0.003305427574 -2.1336 0.0483 0.0239 0.2025 0.1406 0.1488 0.234494101 ORMDL1 ORM1-like 1 (S. cerevisiae) 1.12188602E-11 2.85105721E-10 -2.1340 2.4549 0.6322 1.4240 2.6369 0.8814 0.7103554203 JPX JPX transcript, XIST activator (non-protein coding) 4.99043327E-05 0.000182006381 -2.1358 2.9996 2.0358 1.9745 3.7369 2.9588 2.4283286097 MICU3 EF-hand domain family, member A2 0.00014960005 0.00049421299 -2.1382 2.4597 2.5955 1.2904 1.9305 3.0420 1.70397040 TGFB1 transforming growth factor, beta 1 2.8159876E-09 2.86171999E-08 -2.1387 0.8924 2.4639 1.4614 1.4703 3.1285 2.0132

CD55 molecule, decay accelerating factor for complement (Cromer blood group)

topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

5934 RBL2 retinoblastoma-like 2 3.36199481E-09 3.33860702E-08 -2.1390 2.0843 1.6961 0.7388 1.8670 1.7554 0.81306903 TBCC tubulin folding cofactor C 5.55760083E-07 3.06607737E-06 -2.1393 1.5139 3.8899 2.5680 1.6949 5.6696 4.4960140688 C20orf112 chromosome 20 open reading frame 112 6.3137094E-08 4.40152988E-07 -2.1395 1.3947 3.5618 1.8418 1.1721 3.5466 2.18976007 RHD Rh blood group, D antigen 0.00182379133 0.004766745136 -2.1411 0.1878 0.0928 0.1682 0.3231 0.0457 0.2077111 ADCY5 adenylate cyclase 5 0.02128236784 0.041661819715 -2.1413 0.3114 1.3318 0.6258 0.2419 0.7245 0.56219725 TMEM63A transmembrane protein 63A 4.33002589E-05 0.000159931743 -2.1417 1.3058 1.3959 1.2452 1.1260 1.6766 1.716779752 ZFAND1 zinc finger, AN1-type domain 1 5.51366534E-08 3.88379695E-07 -2.1421 2.5365 1.5063 2.2177 3.0930 2.0404 2.07621997 ELF1 E74-like factor 1 (ets domain transcription factor) 1.61801474E-09 1.77457175E-08 -2.1422 3.4329 3.7174 0.7986 2.4801 3.9325 0.926410632 ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 6.95301053E-12 1.97275479E-10 -2.1429 2.8134 2.8545 1.7770 2.7039 2.7495 2.501850810 HDGFRP3 hepatoma-derived growth factor, related protein 3 7.82469496E-06 3.36565034E-05 -2.1435 0.9155 1.9404 1.1957 0.9486 2.6217 1.0910

7529 YWHAB 1.52838971E-09 1.68945776E-08 -2.1438 2.5368 4.2649 2.3018 1.9216 4.8415 2.871622882 ZHX2 zinc fingers and homeoboxes 2 3.65498227E-07 2.11475098E-06 -2.1447 1.3752 2.4317 1.8359 1.6159 3.4132 2.79198743 TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00174079137 0.004575336577 -2.1457 2.2063 1.7368 1.7290 1.9903 1.2759 1.764110286 BCAS2 breast carcinoma amplified sequence 2 2.06954144E-07 1.27322091E-06 -2.1465 2.8753 2.3673 1.9986 3.0027 2.2809 2.22616609 SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 6.81849507E-05 0.000242482565 -2.1475 1.8541 1.9831 2.1475 1.3660 1.6544 2.105425798 BRI3 brain protein I3 5.74326827E-05 0.000207106765 -2.1482 1.7244 2.5516 2.2182 1.4628 2.4275 2.1586266747 RGL4 Ral-GDS related protein Rgr 0.00012476996 0.000420239011 -2.1483 0.9567 0.8848 1.7820 0.9318 0.6789 1.14619857 CEP350 centrosomal protein 350kDa 1.53210918E-12 6.05945866E-11 -2.1486 0.6782 0.5797 0.5473 0.7028 0.6452 0.556810159 ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 4.81140149E-10 6.29305139E-09 -2.1501 0.9816 0.7410 0.5444 1.1066 1.2070 0.7821427 ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.00033487997 0.001029602349 -2.1505 1.7721 2.1018 1.7444 2.3438 2.9968 2.651223710 GABARAPL1 GABA(A) receptor-associated protein like 1 9.58018597E-07 5.00569511E-06 -2.1508 2.0563 3.1299 1.5023 2.6759 3.8688 2.469859348 ZNF350 zinc finger protein 350 1.86337949E-05 7.38721417E-05 -2.1508 2.5038 3.0648 1.4093 3.3505 4.9725 1.85494900 NRGN neurogranin (protein kinase C substrate, RC3) 0.0135144681 0.028105663689 -2.1514 1.4342 3.4434 1.3450 0.7154 2.3070 1.400583869 TTTY14 testis-specific transcript, Y-linked 14 (non-protein coding) 0.00696369116 0.015714531909 -2.1518 1.5984 1.3512 1.1785 1.5614 0.8984 2.4079284047 CCDC144B hypothetical protein FLJ36492 7.26066726E-07 3.90656396E-06 -2.1518 0.9374 1.8557 1.1750 0.7530 2.1231 1.1102

26256 CABYR 0.01268260023 0.026581380067 -2.1537 0.8100 1.1354 1.0160 0.6352 0.8889 0.87336459 SH3GL1P2 SH3-domain GRB2-like 1 pseudogene 2 0.00687157575 0.015546982668 -2.1569 0.0267 0.0192 0.0790 0.1765 0.2440 0.192257232 ZNF630 zinc finger protein 630 0.000308164 0.000954853754 -2.1597 1.0375 1.3542 1.0377 0.8946 1.9292 1.15657227 TRPS1 trichorhinophalangeal syndrome I 1.24365739E-05 5.11919529E-05 -2.1605 2.3809 2.2743 1.4593 1.8874 2.4287 2.11879748 SLK STE20-like kinase 6.47713856E-12 1.8696726E-10 -2.1608 2.6045 4.0964 1.7713 2.9236 4.9382 2.910355225 RAVER2 ribonucleoprotein, PTB-binding 2 0.00015407039 0.000507512904 -2.1612 0.9269 0.9272 0.9802 0.7464 0.8071 0.9650254048 UBN2 hypothetical protein FLJ25778 1.2644469E-11 3.13061976E-10 -2.1614 0.9937 2.4412 0.7250 1.1035 3.1372 0.977091689 SMDT1 single-pass membrane protein with aspartate-rich tail 1 3.85006684E-07 2.21360671E-06 -2.1617 2.0599 2.4518 1.4931 1.7336 3.0704 2.08955728 PTEN phosphatase and tensin homolog 2.32516886E-10 3.4027619E-09 -2.1633 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970100131755 ARMCX4 armadillo repeat containing, X-linked 4 0.00013146091 0.000439936585 -2.1642 0.6925 0.7532 0.7587 0.5765 1.0111 0.778857562 KIAA1377 KIAA1377 0.00058358632 0.001699058205 -2.1663 0.4970 0.5274 0.4125 0.6502 0.5877 0.529523645 PPP1R15A protein phosphatase 1, regulatory subunit 15A 6.97565188E-08 4.81341054E-07 -2.1667 1.8503 1.1343 1.8345 1.7973 2.1337 2.7826394 ARHGAP5 Rho GTPase activating protein 5 1.11386273E-09 1.28569172E-08 -2.1694 3.3415 4.7340 2.0519 4.5836 6.8336 5.2209

2770 GNAI1 0.00014318836 0.000475957372 -2.1695 2.0030 1.5148 1.7203 1.6422 1.0269 1.4179196528 ARID2 AT rich interactive domain 2 (ARID, RFX-like) 1.55465415E-14 2.36722005E-12 -2.1712 0.4435 1.5705 0.4188 0.8984 2.7118 1.10033561 IL2RG interleukin 2 receptor, gamma 3.05110842E-11 6.34172026E-10 -2.1729 4.3070 2.4578 2.1487 4.0629 3.0960 2.246757804 POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.03809328E-08 3.59313194E-07 -2.1731 1.5906 1.7495 2.2750 1.1312 1.6105 2.294749854 ZBTB21 zinc finger and BTB domain containing 21 3.97822068E-07 2.27511888E-06 -2.1745 1.6566 2.6673 1.4781 2.3284 4.3252 3.702090271 LINC00263 long intergenic non-protein coding RNA 263 0.00029540023 0.000918888843 -2.1748 2.0427 2.5079 2.1190 1.5027 2.4810 1.9866114801 TMEM200A transmembrane protein 200A 0.00823494618 0.018232029149 -2.1750 0.6613 0.6580 0.4250 0.5516 0.3393 0.306223271 CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.2895467E-05 8.91045734E-05 -2.1755 2.7131 4.0295 1.8305 2.5624 3.8168 1.9473641339 ZNF674 zinc finger protein 674 0.00026832923 0.000843004083 -2.1758 0.0672 0.9306 1.7547 0.1036 1.0287 0.620022795 NID2 nidogen 2 (osteonidogen) 0.00032758049 0.001009878637 -2.1776 0.8621 1.5392 1.4824 0.6519 1.3600 1.05254327 MMP19 matrix metallopeptidase 19 0.01624365574 0.032941629046 -2.1802 0.0749 0.1452 0.2301 0.1656 0.2104 0.237526249 KLHL3 kelch-like family member 3 7.1436888E-05 0.000253062198 -2.1804 0.6333 0.6866 0.8997 0.7115 0.5061 0.584979690 GAL3ST4 galactose-3-O-sulfotransferase 4 7.07921514E-05 0.000250972874 -2.1824 2.4448 1.9786 2.3269 1.5949 1.7316 1.2527649446 DLGAP1-AS1 DLGAP1 antisense RNA 1 0.00013790086 0.000459719858 -2.1830 2.6163 3.1880 2.4791 1.7513 2.8476 2.04967013 TERF1 telomeric repeat binding factor (NIMA-interacting) 1 1.67146904E-13 1.17919237E-11 -2.1833 1.8665 2.9764 2.1367 1.4969 4.6035 1.8589647042 GOLGA6L10 golgin A6 family-like 10 0.00014618251 0.000484324008 -2.1839 0.0679 0.1300 0.2664 0.5901 0.0319 0.19794065 LY75 lymphocyte antigen 75 4.30309575E-08 3.13251655E-07 -2.1853 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970642280 ZNF876P zinc finger protein 876, pseudogene 0.02279240806 0.044177668399 -2.1863 0.7448 1.0645 0.4967 0.5807 0.4581 0.4125401149 LINC01061 long intergenic non-protein coding RNA 1061 0.00010205577 0.000350190248 -2.1866 0.0320 0.0679 0.2682 0.1781 0.0343 0.2745163051 ZNF709 zinc finger protein 709 0.00013017974 0.000436128396 -2.1875 0.9815 0.7314 0.7892 1.0255 0.9840 0.994057092 PCNP PEST proteolytic signal containing nuclear protein 4.39333888E-10 5.82547809E-09 -2.1884 2.3418 2.2195 1.9695 2.2247 2.6810 2.617154807 ZNF586 zinc finger protein 586 4.24677324E-09 4.09483064E-08 -2.1892 1.6969 1.2591 1.7377 1.6189 1.5565 2.13924329 ALDH6A1 aldehyde dehydrogenase 6 family, member A1 7.75660504E-05 0.000273396388 -2.1905 2.6756 0.6807 2.3391 1.2529 0.6241 1.27465042 PABPC3 poly(A) binding protein, cytoplasmic 3 4.05675523E-09 3.93653912E-08 -2.1908 0.2806 0.1614 0.3192 0.3223 0.1595 0.391225992 SNED1 sushi, nidogen and EGF-like domains 1 0.00021212576 0.000678564762 -2.1914 0.4965 1.0426 0.3939 0.4497 0.7015 0.3195123283 TARSL2 threonyl-tRNA synthetase-like 2 1.22690292E-05 5.05592471E-05 -2.1917 0.8064 0.5822 0.8176 0.5649 0.4133 0.833610541 ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 1.05750848E-10 1.74162334E-09 -2.1918 1.3797 1.6183 2.2025 1.3573 1.7744 2.99496672 SP100 SP100 nuclear antigen 5.39714948E-07 2.98296175E-06 -2.1922 1.4197 1.9705 1.2065 1.5396 2.3396 1.2231239 ALOX12 arachidonate 12-lipoxygenase 0.00052510826 0.001545091902 -2.1939 0.2250 0.6082 0.4927 0.2384 0.3028 0.322029058 TMEM230 transmembrane protein 230 5.45488692E-11 1.01086911E-09 -2.1954 2.6391 1.0220 2.0955 2.5580 1.5414 2.795651171 HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 0.01895587754 0.037668493133 -2.1964 1.2793 2.0993 1.8769 0.6235 0.6484 1.487556253 CRTAM cytotoxic and regulatory T cell molecule 0.01241290741 0.026087950785 -2.1965 0.5608 0.7034 0.5737 0.5279 0.1925 0.4752

55294 FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 7.60237326E-11 1.31918864E-09 -2.1972 1.4756 1.6056 0.7589 1.1127 1.7902 0.778610133 OPTN optineurin 1.33031185E-09 1.50510576E-08 -2.2000 3.1999 2.4478 1.9639 2.3687 1.7745 2.1833133746 JMY junction mediating and regulatory protein, p53 cofactor 7.60924582E-07 4.07252898E-06 -2.2002 1.0274 0.8629 0.6337 1.1078 1.0495 1.1874440193 CCDC88C coiled-coil domain containing 88C 7.04651064E-09 6.28987995E-08 -2.2014 0.9420 1.0591 1.0991 0.8648 1.3190 1.3837114659 LRRC37B leucine rich repeat containing 37B 2.77980845E-06 1.3138298E-05 -2.2021 1.2836 1.6203 1.3220 1.2131 1.8628 1.64473750 KCND1 potassium voltage-gated channel, Shal-related subfamily, member 1 0.00061805593 0.001788867085 -2.2031 0.2989 0.6509 0.6071 0.2536 0.5741 0.427326054 SENP6 SUMO1/sentrin specific peptidase 6 4.38589479E-14 4.71406292E-12 -2.2032 0.8822 0.9528 0.6667 1.1644 1.2889 1.116356990 CDC42SE2 CDC42 small effector 2 1.13483211E-08 9.56441531E-08 -2.2034 2.5746 4.3328 1.5299 2.5896 6.8715 2.581427127 SMC1B structural maintenance of chromosomes 1B 0.00976029912 0.021178029392 -2.2062 0.1926 0.3042 1.0391 0.2815 0.3240 0.402851247 PAIP2 poly(A) binding protein interacting protein 2 3.03660217E-12 1.02181943E-10 -2.2070 2.3448 2.4622 2.1507 1.8422 2.1221 1.814610154 PLXNC1 plexin C1 0.00016016468 0.000525757021 -2.2076 1.0455 1.1421 1.4169 1.2897 0.8476 1.346064784 CRTC3 CREB regulated transcription coactivator 3 3.24378748E-11 6.65213073E-10 -2.2090 1.0829 3.5832 1.7071 1.6477 4.5359 2.709910179 RBM7 RNA binding motif protein 7 1.84950175E-10 2.77455632E-09 -2.2094 1.1449 4.0653 1.2470 0.3110 1.0727 0.3930

64077 LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 1.14552137E-07 7.48068849E-07 -2.2104 0.4756 0.9806 0.7214 0.5619 0.7574 1.194058476 TP53INP2 tumor protein p53 inducible nuclear protein 2 4.76681264E-05 0.000174582483 -2.2107 1.6713 1.3410 2.1106 1.3105 1.2452 1.574551111 SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 2.62560956E-11 5.67753111E-10 -2.2107 1.0530 2.1047 1.0251 1.3146 1.5675 1.42005937 RBMS1 RNA binding motif, single stranded interacting protein 1 3.02856469E-10 4.26661018E-09 -2.2117 0.9161 1.9966 1.3465 1.1308 2.3643 1.85809990 SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 6.23777037E-09 5.68178167E-08 -2.2122 1.4034 1.7193 1.1658 1.3384 1.5676 0.884551380 CSAD cysteine sulfinic acid decarboxylase 0.00046182639 0.001373005504 -2.2127 0.9303 0.8923 0.8676 0.5479 0.9550 0.4409320 APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.0151990212 0.031113210323 -2.2140 1.5551 2.7821 1.3604 1.0269 1.1358 1.507123067 SETD1B SET domain containing 1B 7.66079861E-10 9.33809955E-09 -2.2154 1.2873 1.9786 4.5034 1.6061 1.4975 6.4045832 CAPZB capping protein (actin filament) muscle Z-line, beta 1.98639435E-11 4.52561066E-10 -2.2165 2.2200 2.7863 2.6764 1.8612 3.2591 3.041810142 AKAP9 A kinase (PRKA) anchor protein 9 1.4005532E-08 1.15638988E-07 -2.2175 0.6685 0.5472 0.5656 0.6321 0.5781 0.62437697 ZNF138 zinc finger protein 138 1.0752888E-06 5.56749134E-06 -2.2181 1.5261 1.5478 1.3036 1.5182 1.8988 1.689780345 ZSCAN16 zinc finger and SCAN domain containing 16 4.14647358E-05 0.000153680254 -2.2181 2.8538 1.9056 2.0862 2.0034 1.8271 1.9553222223 KIAA1324L KIAA1324-like 0.00013898783 0.000463090006 -2.2189 0.8239 0.7443 0.6589 0.8321 0.9690 0.704923085 ERC1 ELKS/RAB6-interacting/CAST family member 1 1.16376182E-12 4.84693833E-11 -2.2205 0.6681 0.8332 0.6339 0.6418 1.0681 0.66465463 POU6F1 POU class 6 homeobox 1 9.28062449E-06 3.92571721E-05 -2.2206 1.4721 0.9575 1.0041 1.5387 1.1830 1.5149170960 ZNF721 zinc finger protein 721 3.45056545E-09 3.41727544E-08 -2.2219 0.6304 0.2524 0.8190 0.3961 0.2377 0.357610464 PIBF1 progesterone immunomodulatory binding factor 1 3.67363269E-13 2.10421995E-11 -2.2231 2.4492 29.4729 1.1535 2.4201 38.6673 0.84471606 DGKA diacylglycerol kinase, alpha 80kDa 4.70709468E-08 3.37949053E-07 -2.2232 3.2718 2.7349 2.9285 2.7089 2.8243 2.610684830 ADTRP chromosome 6 open reading frame 105 1.58630641E-05 6.38717291E-05 -2.2235 1.2545 1.2045 1.1672 1.0662 1.2366 0.931654463 FAM134B family with sequence similarity 134, member B 4.65302066E-08 3.346203E-07 -2.2235 1.3444 1.9266 1.6745 1.1349 1.7081 1.709023345 SYNE1 spectrin repeat containing, nuclear envelope 1 2.34250087E-08 1.81982041E-07 -2.2245 0.7033 0.5956 0.4317 0.7972 0.5636 0.4140337873 HIST2H2BC histone cluster 2, H2bc (pseudogene) 0.00014846466 0.000490639587 -2.2251 2.1009 4.7147 4.7043 1.1761 1.9631 3.592925903 OLFML2B olfactomedin-like 2B 0.02585948688 0.049244871732 -2.2252 0.6604 0.6341 0.9090 0.6214 0.5825 0.911123568 ARL2BP ADP-ribosylation factor-like 2 binding protein 5.59375035E-11 1.03137242E-09 -2.2261 1.5299 1.5397 1.4892 1.1309 1.4018 1.6794203523 ZNF449 zinc finger protein 449 1.40868667E-05 5.73008077E-05 -2.2266 0.8811 0.8488 1.1103 0.9307 1.0353 1.3521648987 LOC648987 uncharacterized LOC648987 3.41214512E-06 1.58441463E-05 -2.2278 3.9561 3.3208 2.0349 5.0496 4.2943 3.23451350 COX7C cytochrome c oxidase subunit VIIc 9.52894853E-13 4.15544028E-11 -2.2283 1.3879 1.3800 0.9698 1.4525 1.9492 1.528423705 CADM1 cell adhesion molecule 1 0.01004849732 0.021723396011 -2.2290 1.0305 0.8995 0.6464 0.7866 0.6332 0.6746256006 ANKRD31 ankyrin repeat domain 31 0.00715668179 0.016090425705 -2.2302 1.5022 1.1155 1.7515 1.0307 0.9581 1.467490 ACVR1 activin A receptor, type I 2.77447362E-06 1.31164766E-05 -2.2302 1.7896 1.5453 1.4515 1.5662 1.2386 1.11839121 SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 0.00017733637 0.00057625649 -2.2314 0.6002 0.7798 0.8730 0.3785 0.4184 0.679210788 IQGAP2 IQ motif containing GTPase activating protein 2 1.82431083E-11 4.23017863E-10 -2.2319 0.9166 1.9368 0.8249 1.0825 1.2757 0.8973

79577 CDC73 5.9051362E-13 2.99771164E-11 -2.2321 2.3245 2.2981 1.7907 2.8232 2.9589 3.22319267 CYTH1 cytohesin 1 4.6939308E-09 4.48078113E-08 -2.2322 1.5005 1.7980 1.0564 1.1190 1.7274 0.754264121 RRAGC Ras-related GTP binding C 5.2449509E-05 0.000190566202 -2.2325 1.4865 1.6713 1.4936 1.0811 1.5225 1.6741440248 HERC2P9 hect domain and RLD 2 pseudogene 9 8.18959795E-07 4.34874553E-06 -2.2338 0.0176 0.0670 0.1438 0.3053 0.0270 0.1918729873 TBC1D3 TBC1 domain family, member 3 9.10018442E-07 4.77998205E-06 -2.2387 0.0425 0.0404 0.1249 0.2306 0.0755 0.167684771 DDX11L2 Hypothetical protein MGC13005 0.01080285239 0.023110844033 -2.2408 0.2866 0.3641 0.5777 0.4529 0.1313 0.343854832 VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 5.02100821E-10 6.5158993E-09 -2.2431 1.2544 1.4208 0.8654 1.3849 1.8813 1.2004374443 LOC374443 CLR pseudogene 0.00010137719 0.000348057871 -2.2431 1.1137 1.2343 1.0469 1.1213 1.3250 1.043850807 ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 9.2823622E-10 1.10134625E-08 -2.2439 1.2313 1.3950 0.8182 0.9514 0.5484 0.5697147694 ZNF548 zinc finger protein 548 1.87134473E-07 1.16422237E-06 -2.2450 0.3321 0.3321 0.3321 0.3970 0.3970 0.397027334 P2RY10 purinergic receptor P2Y, G-protein coupled, 10 1.33000039E-07 8.54192169E-07 -2.2452 2.3921 2.7016 1.8434 2.2525 2.7089 1.836354014 BRWD1 bromodomain and WD repeat domain containing 1 3.3646207E-12 1.11575952E-10 -2.2462 0.5098 0.5545 0.2485 0.9928 0.9549 0.651984707 BEX2 brain expressed X-linked 2 4.72891934E-06 2.12929557E-05 -2.2464 1.0634 1.0064 1.5815 1.2018 1.0672 2.1070285704 RGMB RGM domain family, member B 0.0001760286 0.000572312195 -2.2465 2.3835 4.3579 2.0876 1.7233 1.9453 1.45673248 HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00052210568 0.0015367131 -2.2482 1.8831 2.4896 1.7798 1.5196 2.2003 1.32366935 ZEB1 zinc finger E-box binding homeobox 1 1.42239175E-10 2.21757185E-09 -2.2483 2.4723 1.9157 1.7762 2.0980 1.8840 1.781711174 ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 8.81687385E-05 0.000306743943 -2.2490 1.7886 3.0050 1.1327 1.7652 2.9453 1.061557018 CCNL1 cyclin L1 9.30785961E-11 1.56266211E-09 -2.2503 2.0536 1.8849 1.5576 1.9266 2.0525 1.43479495 AKAP5 A kinase (PRKA) anchor protein 5 0.00041650068 0.001252518174 -2.2534 2.2681 1.8529 1.7910 1.5667 1.0535 1.4723100289410 MCF2L-AS1 MCF2L antisense RNA 1 0.00275178585 0.00690004542 -2.2534 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970646396 REREP3 similar to Zinc finger CCHC domain-containing protein 2 0.00180067982 0.004712924591 -2.2588 0.3749 1.1505 0.4854 0.1321 0.7388 0.673757560 IFT80 intraflagellar transport 80 homolog (Chlamydomonas) 1.89303648E-05 7.49827932E-05 -2.2610 0.8946 1.9355 0.7142 1.2542 0.6375 0.604251157 ZNF580 zinc finger protein 580 2.66563218E-09 2.72559772E-08 -2.2619 1.3119 2.6113 2.4968 0.9241 3.9470 2.8042

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

calcium binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1

cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

51678 MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) 4.41291327E-10 5.84295299E-09 -2.2630 2.1681 1.5906 3.0273 1.9962 2.1182 3.3197

64844 MARCH7 9.02337178E-13 3.99387567E-11 -2.2631 12.6313 0.8593 0.5158 9.9886 1.0059 0.4489100131067 CKMT2-AS1 CKMT2 antisense RNA 1 0.00011036804 0.00037588907 -2.2635 1.7942 0.3264 1.2750 0.2742 1.2520 0.475764089 SNX16 sorting nexin 16 8.88227056E-05 0.000308725219 -2.2671 0.6076 0.5029 0.6084 0.7535 0.8646 0.91528395 PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.00362058677 0.008819538928 -2.2679 1.0958 0.4634 1.1932 0.7604 0.3673 1.00975020 OXT oxytocin/neurophysin I prepropeptide 0.00072262458 0.002064060713 -2.2693 1.2075 2.7932 1.6130 1.0517 2.4692 1.5995100506215 PAXBP1-AS1 PAXBP1 antisense RNA 1 8.14841675E-05 0.000285883008 -2.2714 2.7004 1.9982 0.9642 2.7358 0.6348 0.705626206 SPAG8 sperm associated antigen 8 0.01245795001 0.026161551844 -2.2716 2.4630 1.0338 1.3093 1.5227 0.8091 0.9140397 ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 7.90460423E-09 6.93388999E-08 -2.2754 2.9021 2.5585 1.5946 3.3528 3.8450 2.865911145 PLA2G16 phospholipase A2, group XVI 0.00035202494 0.001075438828 -2.2759 1.6804 1.8547 1.7245 0.9970 1.4252 1.4354775 CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.00023443218 0.000744446449 -2.2764 0.6685 1.5892 0.7011 0.4149 0.5942 0.47261521 CTSW cathepsin W 1.10866481E-05 4.61026932E-05 -2.2765 0.9614 0.8509 1.0948 0.6337 0.4579 0.672310006 ABI1 abl-interactor 1 2.89828307E-11 6.11003541E-10 -2.2771 0.9243 1.1099 0.7487 0.9971 0.8266 0.98342309 FOXO3 forkhead box O3 6.63634927E-12 1.90360085E-10 -2.2777 1.1302 1.0632 0.8275 1.2956 1.2205 1.07576191 RPS4X ribosomal protein S4, X-linked 2.48468686E-10 3.60891878E-09 -2.2778 1.8125 2.0687 1.5659 1.9673 2.6628 1.77579826 ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.00114064368 0.00313458284 -2.2790 0.3674 0.4598 0.5251 0.3630 0.4184 0.3689100506144 ZMYM6NB ZMYM6 neighbor 5.3841417E-08 3.80723828E-07 -2.2799 0.3321 0.3321 0.3321 0.3970 0.3970 0.397083852 SETDB2 SET domain, bifurcated 2 3.34633068E-05 0.000125992487 -2.2800 0.8443 0.6285 1.2311 0.7139 1.0354 1.1273100133036 FAM95B1 family with sequence similarity 95, member B1 0.02577101877 0.049107107621 -2.2814 0.0702 0.0613 0.1290 0.1770 0.0610 0.2041152756 FAM218A family with sequence similarity 218, member A 0.00718988188 0.016156082205 -2.2815 1.2303 1.9501 1.5517 1.4771 2.7086 1.93831106 CHD2 chromodomain helicase DNA binding protein 2 3.5645153E-10 4.90073917E-09 -2.2820 1.8887 2.5191 0.8168 1.5061 1.8098 0.716810608 MXD4 MAX dimerization protein 4 0.00014151101 0.000470895871 -2.2820 0.6542 2.1499 1.4619 0.6905 1.5070 1.82646209 RPS15 ribosomal protein S15 5.56159711E-11 1.02647982E-09 -2.2822 1.0974 1.6639 1.6174 1.0084 3.6802 1.893456946 C11orf30 chromosome 11 open reading frame 30 4.11465932E-11 8.00671514E-10 -2.2823 0.5979 0.9161 0.4862 0.7007 1.1565 0.750254495 TMX3 thioredoxin-related transmembrane protein 3 7.91187083E-13 3.63230412E-11 -2.2853 3.7492 2.1666 1.5805 1.8164 0.9946 1.467930832 ZNF354C zinc finger protein 354C 3.66334038E-07 2.11891597E-06 -2.2880 1.8384 1.7117 1.4074 1.9840 1.2957 1.8951100506776 TRG-AS1 T cell receptor gamma locus antisense RNA 1 4.42808631E-05 0.000163256645 -2.2883 0.9887 0.9739 1.1202 0.7496 0.2581 0.566655824 PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 9.28568294E-08 6.19678593E-07 -2.2888 0.8563 2.0471 1.1630 1.2889 2.4213 1.60216229 RPS24 ribosomal protein S24 3.39394008E-10 4.69803584E-09 -2.2889 1.4770 2.0913 1.4442 1.4691 3.8872 1.472380206 FHOD3 formin homology 2 domain containing 3 0.00131178405 0.003554110053 -2.2913 0.1821 0.2622 0.3602 0.2493 0.3147 0.3149642819 ZNF487 zinc finger protein 487 0.00326285478 0.008038203215 -2.2938 1.2337 1.6003 1.9759 1.2515 1.9206 2.6308715 C1R complement component 1, r subcomponent 0.00011938779 0.000403375305 -2.2938 1.0599 0.6385 0.8294 0.8625 0.4917 0.8245414059 TBC1D3B TBC1 domain family, member 3B 0.00010349654 0.000354733969 -2.2946 0.0516 0.0507 0.1451 0.1417 0.2382 0.1029401375 GTF2IRD2P1 GTF2I repeat domain containing 2 pseudogene 1 9.04842797E-05 0.000313665103 -2.2958 0.0973 0.3116 0.1775 0.1845 0.0194 0.141956252 YLPM1 YLP motif containing 1 7.07221155E-14 6.32505674E-12 -2.2963 0.7868 1.0693 0.8948 0.7671 0.7427 0.7928

79101 TAF1D 7.23293593E-09 6.42802555E-08 -2.2983 2.3081 1.4435 0.5990 1.3666 1.8847 0.734979612 NAA16 NMDA receptor regulated 1-like 3.35159915E-10 4.65528668E-09 -2.2983 1.5504 1.7668 1.6641 2.1784 2.2354 2.6242

8028 MLLT10 8.2215853E-15 1.53290619E-12 -2.2998 0.7415 0.8244 0.6424 0.7685 0.8899 0.702823117 NPIPB3 nuclear pore complex interacting protein family, member B3 1.00235326E-05 4.21034453E-05 -2.3000 0.1333 0.1675 0.2010 0.3796 0.1368 0.1669221895 JAZF1 JAZF zinc finger 1 2.95971319E-07 1.75129143E-06 -2.3006 0.2800 0.5056 0.4239 0.2564 0.1377 0.29841633 DCK deoxycytidine kinase 1.80331659E-09 1.94741139E-08 -2.3026 2.4033 1.6090 2.0499 2.8015 2.2113 3.0242220136 CCDC11 coiled-coil domain containing 11 0.01351276261 0.028105315708 -2.3063 1.8949 1.3894 1.3169 1.2739 0.9406 1.0284284593 FAM41C family with sequence similarity 41, member C 0.01342707889 0.027952556165 -2.3082 0.0289 0.0055 0.1138 0.1139 0.0515 0.27062086 ERV3-1 endogenous retrovirus group 3, member 1 8.69748096E-05 0.000303160622 -2.3083 1.7866 1.7161 1.1686 1.1943 1.6863 1.18166919 TCEA2 transcription elongation factor A (SII), 2 2.65434193E-07 1.58548989E-06 -2.3084 0.8709 1.2791 1.0753 0.5761 1.4407 0.66621962 EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.00046136599 0.001371859944 -2.3093 1.0856 0.8543 1.2628 0.9700 0.7565 1.2338

6595 SMARCA2 1.92927236E-11 4.43417164E-10 -2.3097 2.2721 2.5500 1.5408 1.7375 2.8289 1.850023131 GPATCH8 G patch domain containing 8 3.38330069E-14 4.0142643E-12 -2.3100 0.8865 1.2963 1.0512 0.9685 1.9099 1.186453833 IL20RB interleukin 20 receptor beta 0.00166392592 0.004397061396 -2.3101 0.0855 0.1197 0.2090 0.2392 0.2958 0.1498219402 MTIF3 mitochondrial translational initiation factor 3 1.11164904E-09 1.28439057E-08 -2.3111 2.1084 2.7708 1.7501 1.9672 1.8409 1.78714482 MSRA methionine sulfoxide reductase A 8.87833347E-07 4.67372253E-06 -2.3118 0.9001 1.0318 0.8359 0.8884 1.0439 1.12375734 PTGER4 prostaglandin E receptor 4 (subtype EP4) 8.06849768E-08 5.48261769E-07 -2.3125 2.1751 3.0306 1.5541 2.9080 4.8716 2.911655285 RBM41 RNA binding motif protein 41 2.10740259E-07 1.29433479E-06 -2.3149 2.5869 1.8555 1.2917 2.0286 2.5030 2.0707168374 ZNF92 zinc finger protein 92 2.21118891E-10 3.25042991E-09 -2.3153 1.3961 1.8153 1.2644 1.3242 2.7066 1.8190

522 ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 7.35921246E-11 1.28677062E-09 -2.3154 2.4809 4.4542 1.9109 1.7599 4.0336 1.94036815 STYX serine/threonine/tyrosine interacting protein 3.1628901E-12 1.05992379E-10 -2.3157 2.6525 2.0228 1.4349 2.3152 2.3884 2.114023461 ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 2.53694609E-05 9.77336684E-05 -2.3160 0.4298 0.5075 0.3824 0.4115 0.4224 0.46506275 S100A4 S100 calcium binding protein A4 9.74853281E-05 0.000335641966 -2.3162 1.8299 1.6780 2.2606 1.1752 1.1362 1.6765

387990 TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 0.00404527741 0.00974750215 -2.3176 1.3702 1.3181 1.5313 1.1976 0.9555 1.228554941 RNF125 ring finger protein 125, E3 ubiquitin protein ligase 3.60926283E-09 3.54958945E-08 -2.3184 1.7937 1.3352 1.9495 2.0899 1.9290 2.74358545 CGGBP1 CGG triplet repeat binding protein 1 1.53756939E-11 3.66967362E-10 -2.3195 2.8472 8.6883 1.1173 2.9106 5.2530 2.235554923 LIME1 Lck interacting transmembrane adaptor 1 0.00265287379 0.00668874154 -2.3197 0.8294 0.8061 0.8080 0.8874 0.2477 0.4875144110 TMEM86A transmembrane protein 86A 0.00887054665 0.019456251286 -2.3203 1.2429 1.3741 1.6237 1.1711 1.0145 1.3293128338 DRAM2 DNA-damage regulated autophagy modulator 2 3.5128202E-08 2.59758198E-07 -2.3236 1.7287 1.2819 0.9426 0.3572 1.0831 0.38415217 PFN2 profilin 2 0.00041264256 0.001242142488 -2.3236 1.4554 5.1402 3.3757 1.4570 10.0361 1.871265125 WNK1 WNK lysine deficient protein kinase 1 2.77702025E-10 3.98494957E-09 -2.3267 1.1675 0.8442 0.6411 1.3667 1.0151 1.001383989 FAM172A family with sequence similarity 172, member A 3.82719832E-10 5.19543593E-09 -2.3274 2.1702 1.6367 1.2465 1.8931 1.6547 1.786863908 NAPB N-ethylmaleimide-sensitive factor attachment protein, beta 2.29618579E-05 8.93439239E-05 -2.3293 0.6147 0.5208 0.8746 0.7615 0.4979 0.99182625 GATA3 GATA binding protein 3 1.14275025E-05 4.7379924E-05 -2.3316 1.2718 2.6010 1.4402 2.1619 3.4541 2.7024112942 CCDC104 coiled-coil domain containing 104 1.2078619E-10 1.94278632E-09 -2.3316 3.0222 2.4432 1.5705 3.5600 3.4245 2.42849882 TBC1D4 TBC1 domain family, member 4 9.75618935E-07 5.0889264E-06 -2.3342 1.2606 2.5065 1.3300 1.1899 2.2557 1.56148100 IFT88 intraflagellar transport 88 homolog (Chlamydomonas) 4.54065556E-05 0.000166868178 -2.3349 0.4990 1.0477 0.6075 0.4866 1.0387 0.701626052 DNM3 dynamin 3 8.14282898E-05 0.00028574183 -2.3365 0.9091 1.1619 1.1380 0.7627 0.8565 1.0854441242 LOC441242 uncharacterized LOC441242 0.00134465645 0.003631864396 -2.3366 2.2203 9.2859 1.6942 1.1725 3.8147 1.70247163 TPD52 tumor protein D52 3.1879398E-06 1.48597031E-05 -2.3369 0.5745 0.8501 0.7111 0.6162 0.9752 0.777156606 SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 0.00667016931 0.015140041442 -2.3373 0.0967 0.0522 0.1984 0.2227 0.0315 0.1545388789 LINC00493 long intergenic non-protein coding RNA 493 1.173037E-10 1.90183958E-09 -2.3384 2.4764 1.7290 2.2991 1.8871 2.3711 2.2363147081 CRHR1-IT1 chromosome 17 open reading frame 69 6.93613837E-05 0.000246282783 -2.3386 0.2048 0.1754 0.2212 0.2579 0.1997 0.26579311 ASIC3 acid-sensing (proton-gated) ion channel 3 0.00049559542 0.001465294431 -2.3388 0.0615 0.1590 0.1209 0.2853 0.0546 0.1199154881 KCTD7 potassium channel tetramerization domain containing 7 4.18565749E-06 1.90249586E-05 -2.3400 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970149076 ZNF362 zinc finger protein 362 1.70141604E-12 6.49024509E-11 -2.3407 1.1339 2.6203 2.5268 1.3464 2.6439 2.55818289 ARID1A AT rich interactive domain 1A (SWI-like) 1.73315214E-11 4.04963631E-10 -2.3426 1.0323 0.9711 0.9246 0.8410 0.9243 1.0500253827 MSRB3 methionine sulfoxide reductase B3 0.02172970101 0.042399611241 -2.3428 0.8327 0.8079 0.8760 0.9342 1.0510 0.807680705 TSGA10 testis specific, 10 9.73556554E-05 0.000335258676 -2.3442 2.9375 2.0106 0.7927 1.1757 2.3079 0.4871114785 MBD6 methyl-CpG binding domain protein 6 1.08528106E-13 8.49158113E-12 -2.3452 1.0558 1.4003 1.6524 0.6428 1.4927 1.5536340527 NHSL2 NHS-like 2 0.02449710188 0.047062458786 -2.3453 0.7924 2.2909 0.9538 0.5417 0.6697 0.58464131 MAP1B microtubule-associated protein 1B 0.00582921633 0.013441625535 -2.3468 0.1213 0.3020 0.7930 0.2097 0.1692 0.7461121536 AEBP2 AE binding protein 2 1.51746672E-10 2.35175165E-09 -2.3475 2.5076 3.0186 0.9166 2.5284 4.5160 2.0127375248 ANKRD36 ankyrin repeat domain 36 4.95637095E-08 3.54176027E-07 -2.3494 0.5857 1.2529 0.5323 0.6662 1.8112 0.7774143879 KBTBD3 kelch repeat and BTB (POZ) domain containing 3 4.21251313E-05 0.000155811822 -2.3496 1.9791 2.0590 0.0802 0.7846 4.0827 0.69418227 AKAP17A A kinase (PRKA) anchor protein 17A 3.90612751E-08 2.8675276E-07 -2.3521 0.9686 2.2344 0.9109 0.8577 2.7656 1.7119158431 ZNF782 zinc finger protein 782 5.4023673E-05 0.000195935005 -2.3523 1.7894 2.1834 1.9598 1.3566 1.7503 1.936910472 ZBTB18 zinc finger and BTB domain containing 18 6.30120117E-07 3.43483138E-06 -2.3549 1.7487 1.1779 1.4140 1.5441 1.3388 1.58386990 DYNLT3 dynein, light chain, Tctex-type 3 1.19159135E-09 1.36420785E-08 -2.3559 3.6066 2.4294 1.3233 3.3468 1.8542 1.48211029 CDKN2A cyclin-dependent kinase inhibitor 2A 0.01812525118 0.036222748509 -2.3561 0.5838 0.7504 0.9970 0.6138 0.4830 0.663326136 TES testis derived transcript (3 LIM domains) 2.7597954E-11 5.89789258E-10 -2.3567 0.9556 1.1233 0.6612 0.9139 1.7027 0.716780204 FBXO11 F-box protein 11 6.48797096E-14 5.95719625E-12 -2.3585 0.8855 1.0757 0.4905 0.9527 1.5234 1.1061728806 NSFP1 N-ethylmaleimide-sensitive factor pseudogene 1 4.16956445E-08 3.04136853E-07 -2.3608 0.7845 0.8419 0.9149 0.7382 0.8970 1.1928100129842 ZNF737 zinc finger protein 737 3.27433131E-05 0.000123341512 -2.3611 1.2425 1.2890 1.2145 1.6382 2.0768 1.960091526 ANKRD44 ankyrin repeat domain 44 5.69117637E-13 2.94586897E-11 -2.3616 2.0127 1.6673 1.7002 1.5831 1.0017 1.5726

170082 TCEANC 0.00086909254 0.002447981948 -2.3631 1.5997 2.5014 1.4286 1.1680 2.1929 1.189523580 CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00554440552 0.012874237848 -2.3635 0.9607 2.2089 1.3889 0.7813 1.6104 1.27814117 MAK male germ cell-associated kinase 0.00592400219 0.013641256218 -2.3661 0.7881 1.0448 1.0762 0.5616 0.6107 0.85682804 GOLGB1 golgin B1 4.52442524E-13 2.46777009E-11 -2.3666 1.2668 1.4481 1.1786 1.2479 1.4679 1.553523177 CEP68 centrosomal protein 68kDa 3.02556468E-08 2.27035391E-07 -2.3673 1.0089 1.2674 1.4059 1.0886 1.1086 1.3769203 AK1 adenylate kinase 1 0.00213757162 0.00550884467 -2.3673 0.4729 0.2963 0.5084 0.4251 0.9466 0.299922863 ATG14 autophagy related 14 3.61136536E-09 3.54958945E-08 -2.3681 0.9436 1.2223 1.1132 0.9998 1.2987 1.243022982 DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 3.70432492E-05 0.000138671225 -2.3683 0.4071 0.3431 0.4708 0.3184 0.2783 0.387979780 CCDC82 coiled-coil domain containing 82 2.39244463E-15 6.7253459E-13 -2.3703 1.4255 1.5890 1.2833 0.7305 1.4428 0.770522858 ICK intestinal cell (MAK-like) kinase 1.12287325E-07 7.34854586E-07 -2.3712 2.1552 1.7869 1.8057 1.6836 1.7517 1.765583941 TM2D1 TM2 domain containing 1 7.09153839E-13 3.38320077E-11 -2.3713 2.2306 3.0445 1.5712 2.7560 4.3339 2.148093164 HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 0.00137828476 0.00371062606 -2.3720 0.4076 2.0973 0.7656 0.3998 1.4496 2.049928968 SLC6A16 solute carrier family 6, member 16 9.49143605E-05 0.000327716401 -2.3720 0.1581 0.2214 0.1522 0.1550 0.1328 0.1771338758 LINC00936 long intergenic non-protein coding RNA 936 0.00155607705 0.004141680975 -2.3724 1.6800 4.2299 1.5151 1.8979 7.6064 3.855451199 NIN ninein (GSK3B interacting protein) 2.79735445E-12 9.59178495E-11 -2.3735 1.3008 1.2351 1.3953 1.3002 1.0909 1.509022973 LAMB2P1 laminin, beta 2 pseudogene 1 8.90423896E-05 0.000309429925 -2.3735 0.0674 0.0326 0.1639 0.3449 0.0342 0.175950650 ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 2.1484729E-06 1.04046904E-05 -2.3764 1.4991 2.3564 1.4312 1.3487 2.0538 1.458825850 ZNF345 zinc finger protein 345 0.00054017648 0.001583778027 -2.3770 0.8322 1.6208 1.3098 0.8902 1.5208 0.79599534 ZNF254 zinc finger protein 254 4.62734021E-08 3.33139323E-07 -2.3791 1.3610 2.2158 1.5391 1.6018 2.4686 1.91732005 ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 1.22757272E-10 1.97275363E-09 -2.3802 0.9162 0.5961 0.9503 0.7465 0.5882 0.7771196883 ADCY4 adenylate cyclase 4 0.00512870406 0.012037466989 -2.3807 0.6946 2.1108 1.2549 0.4534 1.7421 0.738751601 LIPT1 lipoyltransferase 1 4.88905209E-05 0.000178594082 -2.3833 0.8929 2.1637 3.0381 0.5378 5.0643 0.929957181 SLC39A10 solute carrier family 39 (zinc transporter), member 10 1.55431874E-08 1.26393022E-07 -2.3859 1.8149 3.1572 1.2758 2.3721 4.6436 1.7004285464 CRIPAK cysteine-rich PAK1 inhibitor 3.72206313E-05 0.000139306714 -2.3868 0.0737 0.0232 0.1024 0.4323 0.0365 0.1389100505894 TMEM161B-AS1 TMEM161B antisense RNA 1 5.27381607E-05 0.000191576873 -2.3871 2.3365 19.9028 2.3716 1.0807 16.9473 2.4705100134713 NDUFB2-AS1 NDUFB2 antisense RNA 1 0.00081104434 0.002295802055 -2.3882 2.3505 1.8110 3.3096 1.1660 1.8429 1.7938497190 CLEC18B secretory protein LOC497190 0.00995934742 0.021556171059 -2.3887 0.0409 0.0190 0.1196 0.1553 0.0498 0.228255026 TMEM255A transmembrane protein 255A 0.01189116326 0.025121440058 -2.3889 0.9471 0.6185 1.0433 0.6144 0.5272 0.781055088 C10orf118 chromosome 10 open reading frame 118 6.18622968E-13 3.05499429E-11 -2.3891 0.2732 0.1888 0.1806 0.2400 0.1198 0.322922848 AAK1 AP2 associated kinase 1 9.44388795E-11 1.58020806E-09 -2.3895 2.0984 2.7083 1.6699 2.3060 3.2833 2.9259767811 H2BFXP H2B histone family, member X, pseudogene 0.00226532403 0.005794764196 -2.3900 0.0479 0.0124 0.0759 0.1138 0.0371 0.307183452 RAB33B RAB33B, member RAS oncogene family 4.29799297E-09 4.13331198E-08 -2.3907 1.5315 3.0924 2.7028 1.5848 3.4096 4.52362796 GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.00055290692 0.00161695185 -2.3914 0.0344 0.0261 0.1506 0.1100 0.3109 0.18254703 NEB nebulin 0.00235771018 0.006011733252 -2.3918 0.0719 0.0635 0.1133 0.1775 0.0683 0.20296161 RPL32 ribosomal protein L32 5.21487713E-09 4.88396899E-08 -2.3924 1.4294 1.7788 2.0138 1.2283 2.8354 1.82178648 NCOA1 nuclear receptor coactivator 1 2.18462607E-10 3.2139684E-09 -2.3928 0.2741 0.1567 0.1929 0.3830 0.0696 0.2716

membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase

TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

transcription elongation factor A (SII) N-terminal and central domain containing

6653 SORL1 sortilin-related receptor, L(DLR class) A repeats containing 6.71655663E-06 2.92759835E-05 -2.3962 0.8673 1.1685 1.2233 0.9398 1.3457 1.09915936 RBM4 RNA binding motif protein 4 2.97590473E-12 1.0050967E-10 -2.3971 3.3234 1.8633 2.1478 3.0864 2.1771 1.8510550643 LOC550643 uncharacterized LOC550643 2.54068518E-12 8.85942741E-11 -2.3972 2.1749 2.9911 1.3714 2.9401 3.8302 2.38745836 PYGL phosphorylase, glycogen, liver 0.02389929181 0.046078702107 -2.3975 0.6959 0.8319 0.8945 0.4407 0.7569 0.716251686 OAZ3 ornithine decarboxylase antizyme 3 0.01468723723 0.030187311443 -2.3993 0.2655 0.5067 0.5658 0.4647 0.6881 0.282679890 RIN3 Ras and Rab interactor 3 1.91558264E-06 9.39638279E-06 -2.3995 1.1754 1.5955 1.4733 1.0101 1.6875 1.4944688 KLF5 Kruppel-like factor 5 (intestinal) 2.81320047E-05 0.000107492261 -2.4014 0.7634 1.5762 1.1229 0.8325 1.2610 0.8274653361 NCF1 neutrophil cytosolic factor 1 0.00653856819 0.014882002731 -2.4023 0.3769 0.3730 0.5665 0.1744 0.2741 0.379523639 LRRC6 leucine rich repeat containing 6 0.00851236838 0.0187598595 -2.4028 1.1136 2.5480 1.4470 0.8265 1.2384 1.4017

8148 TAF15 8.28552778E-12 2.25287446E-10 -2.4031 1.9122 3.1064 1.8023 2.2706 3.6582 2.84835295 PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.09225316E-07 7.16612196E-07 -2.4037 1.5981 1.2250 1.1086 1.2554 1.6293 1.1971440452 TBC1D3P2 TBC1 domain family, member 3 pseudogene 2 0.00353300411 0.008630354432 -2.4050 0.0668 0.0181 0.1354 0.0722 0.0098 0.186151237 MZB1 marginal zone B and B1 cell-specific protein 0.02286575087 0.04428224694 -2.4067 0.5175 0.9943 2.2530 0.4114 0.8787 1.174055423 SIRPG signal-regulatory protein gamma 5.3166713E-08 3.76535729E-07 -2.4097 3.1671 2.0399 2.5162 2.6726 1.8159 1.4248129285 PPP1R21 protein phosphatase 1, regulatory subunit 21 1.63055758E-09 1.78725543E-08 -2.4107 2.6347 1.8307 1.6458 2.1109 2.0605 2.1361641649 TMEM91 transmembrane protein 91 1.61118862E-05 6.47736818E-05 -2.4111 1.2594 0.8340 1.6024 0.8273 0.8008 1.27209728 SECISBP2L SECIS binding protein 2-like 2.8396289E-13 1.75883726E-11 -2.4117 1.7979 1.3128 1.1761 1.7545 2.1489 1.63169453 GGPS1 geranylgeranyl diphosphate synthase 1 5.65762024E-12 1.68915093E-10 -2.4126 3.9323 5.3260 1.6348 3.2243 5.3637 2.6682100128782 LINC00476 long intergenic non-protein coding RNA 476 6.65753184E-06 2.90672453E-05 -2.4128 0.3321 0.3321 0.3321 0.3970 0.3970 0.39707637 ZNF84 zinc finger protein 84 1.01316697E-09 1.18220847E-08 -2.4134 1.2581 0.8144 0.7162 1.1937 1.1336 1.006481558 FAM117A family with sequence similarity 117, member A 5.16738409E-07 2.87073403E-06 -2.4135 4.7349 1.7890 2.0199 2.3373 1.5286 2.378551301 GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 8.07710839E-05 0.000283599009 -2.4135 0.4677 0.8219 0.2272 0.3607 0.4558 0.1410128611 ZNF831 zinc finger protein 831 5.40097381E-06 2.40523016E-05 -2.4146 0.1631 0.0653 0.1345 0.1018 0.0306 0.3373773 CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.00101039072 0.002803197575 -2.4155 0.0960 0.6086 0.3208 0.2592 0.5612 0.3438151050 KANSL1L KAT8 regulatory NSL complex subunit 1-like 1.07653551E-05 4.48892215E-05 -2.4157 1.4854 1.4951 0.9202 1.2318 1.8006 1.235128996 HIPK2 homeodomain interacting protein kinase 2 5.86027778E-11 1.07293583E-09 -2.4179 1.0888 3.8520 1.9317 1.8165 2.6464 3.7459100499466 LINC00674 long intergenic non-protein coding RNA 674 4.90806925E-10 6.38748157E-09 -2.4179 1.2692 2.3395 1.5615 1.5090 2.4075 1.905879843 FAM124B family with sequence similarity 124B 0.00495418691 0.011669834108 -2.4190 2.4961 2.3113 1.2461 1.7467 1.4414 0.8618157378 TMEM65 transmembrane protein 65 9.60897977E-08 6.38687808E-07 -2.4198 0.8723 2.2504 1.5925 0.9433 3.4295 2.0814169834 ZNF883 zinc finger protein 883 3.72878371E-05 0.000139501097 -2.4214 0.6759 0.3892 0.6190 0.6207 0.4508 0.5724765 CA6 carbonic anhydrase VI 0.00179445939 0.004698819428 -2.4225 1.2435 1.3823 1.6809 0.6431 0.4246 0.613610559 SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.7691632E-08 2.10650083E-07 -2.4253 0.8078 0.7041 0.7527 0.8026 0.9628 0.94049734 HDAC9 histone deacetylase 9 0.02349719401 0.045360879973 -2.4281 0.3523 0.2630 0.5782 0.4404 0.2321 0.37326311 ATXN2 ataxin 2 1.6265813E-12 6.283487E-11 -2.4286 0.9341 1.0428 0.8777 0.8391 1.2340 1.3991201456 FBXO15 F-box protein 15 0.00036071915 0.001099526032 -2.4301 0.4016 0.3631 1.1568 0.3011 0.3800 0.8371100130894 VAC14-AS1 VAC14 antisense RNA 1 0.00197993533 0.005138102298 -2.4311 0.0390 0.0297 0.1933 0.0726 0.0190 0.1891171425 CLYBL citrate lyase beta like 8.06600751E-07 4.28685542E-06 -2.4314 1.5208 2.5596 2.3973 1.0356 2.0195 2.46932826 CCR10 chemokine (C-C motif) receptor 10 0.01707377878 0.034387880585 -2.4320 0.4298 0.7162 1.1162 0.0917 0.7313 0.741354033 RBM11 RNA binding motif protein 11 0.00028385772 0.000886000717 -2.4321 1.7840 1.2518 1.3800 1.6865 1.5306 1.5206285533 RNF175 ring finger protein 175 0.00727153419 0.016311975575 -2.4325 1.2726 1.7640 1.1571 1.2578 2.2766 0.9190100233209 PCED1B-AS1 PCED1B antisense RNA 1 1.04795794E-07 6.90028376E-07 -2.4334 2.9745 7.6428 2.7294 2.6301 11.9970 3.594854851 ANKRD49 ankyrin repeat domain 49 1.00932662E-09 1.17993705E-08 -2.4343 1.1605 0.4858 0.5595 0.8606 0.4852 0.2437284702 HNRNPU-AS1 hypothetical protein LOC284702 1.09938242E-06 5.67936545E-06 -2.4344 0.3335 0.1446 0.3456 0.4898 0.0810 0.28275101 PCDH9 protocadherin 9 0.00624293326 0.014285645161 -2.4352 2.0314 2.1824 1.2348 1.6907 1.6393 1.239210747 MASP2 mannan-binding lectin serine peptidase 2 0.00030378825 0.000943054528 -2.4362 0.0098 0.0729 0.0407 0.0727 0.0702 0.14368420 SNHG3 small nucleolar RNA host gene 3 (non-protein coding) 5.81569916E-08 4.07937634E-07 -2.4366 0.3321 0.3321 0.3321 0.3970 0.3970 0.397057396 CLK4 CDC-like kinase 4 9.1740288E-08 6.13347436E-07 -2.4374 0.9576 0.9884 0.8109 1.4199 1.7361 1.579280790 CMIP c-Maf-inducing protein 8.34448509E-11 1.42097327E-09 -2.4388 0.6659 0.5926 0.4656 0.6802 0.6049 0.724455366 LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00322891769 0.007967425247 -2.4390 0.9217 0.8766 1.6679 0.8000 0.8897 1.61411955 MEGF9 multiple EGF-like-domains 9 1.70312489E-07 1.06939856E-06 -2.4401 1.0247 1.5593 1.6832 0.9713 2.1197 2.041257597 BAHCC1 BAH domain and coiled-coil containing 1 0.00397227045 0.009589288633 -2.4405 0.2993 0.2362 0.4974 0.3051 0.6266 0.4680196394 AMN1 Antagonist of mitotic exit network 1 homolog (S. cerevisiae) 0.00035797496 0.001092337758 -2.4415 2.2347 2.0032 2.3551 2.3978 2.3498 2.5313150709 ANKAR ankyrin and armadillo repeat containing 2.52941195E-05 9.74639714E-05 -2.4416 0.4418 0.5166 0.4680 0.6108 0.4146 0.4907147657 ZNF480 zinc finger protein 480 1.55234826E-06 7.7710979E-06 -2.4428 2.1164 0.9951 2.0021 2.2362 0.9301 1.8080

130540 ALS2CR12 8.27607098E-05 0.000289916351 -2.4429 0.1155 0.0453 0.1749 0.1949 0.0226 0.19037188 TRAF5 TNF receptor-associated factor 5 1.8342319E-09 1.97496083E-08 -2.4475 1.1847 1.1353 1.0463 0.7759 1.1534 1.025332 ACACB acetyl-CoA carboxylase beta 7.22539242E-07 3.89216894E-06 -2.4476 0.2074 0.3412 0.1934 0.1878 0.2692 0.1826

145165 ST13P4 3.44829785E-10 4.76245641E-09 -2.4487 0.0652 0.1395 0.1585 0.5395 0.0485 0.3416284129 SLC26A11 solute carrier family 26, member 11 0.00017039997 0.000555990773 -2.4497 0.3321 0.3321 0.3321 0.3970 0.3970 0.397023248 RPRD2 regulation of nuclear pre-mRNA domain containing 2 1.39643482E-11 3.40662978E-10 -2.4501 2.3879 1.9511 1.5441 3.5859 3.2057 3.201265117 RSRC2 arginine/serine-rich coiled-coil 2 2.33418924E-10 3.41202447E-09 -2.4510 1.5769 0.9317 0.8987 1.3311 1.7230 1.169455274 PHF10 PHD finger protein 10 9.93564571E-14 7.94985408E-12 -2.4537 1.0863 1.4584 0.8084 1.2381 2.0592 1.5991147660 ZNF578 zinc finger protein 578 0.00246048099 0.006248493217 -2.4549 1.1480 0.4525 0.7689 1.9627 0.4492 0.7337256309 CCDC110 coiled-coil domain containing 110 0.02080511441 0.040858883335 -2.4573 1.9494 1.8068 1.5315 1.2803 1.2694 1.42314638 MYLK myosin light chain kinase 0.01498199874 0.03073092512 -2.4592 0.1759 0.0999 0.2653 0.2074 0.0456 0.2111324 APC adenomatous polyposis coli 7.65329521E-13 3.55232047E-11 -2.4594 1.2700 1.4522 1.3120 1.2407 1.4684 1.15595537 PPP6C protein phosphatase 6, catalytic subunit 4.3100642E-14 4.71406292E-12 -2.4603 2.7012 2.2932 1.8661 3.0431 3.8884 2.752583940 TATDN1 TatD DNase domain containing 1 1.67920072E-09 1.83287668E-08 -2.4604 0.4559 4.6106 1.5428 0.2146 0.3331 0.169324149 ZNF318 zinc finger protein 318 3.53346685E-13 2.04314894E-11 -2.4622 2.3590 4.3139 2.5084 1.7592 4.4048 2.493123272 FAM208A family with sequence similarity 208, member A 2.771805E-13 1.72266738E-11 -2.4634 0.6246 0.5341 0.5281 0.8057 0.7498 0.76023550 IK IK cytokine, down-regulator of HLA II 2.62562444E-13 1.64299348E-11 -2.4638 1.4438 0.2440 0.5718 0.3389 0.2477 0.275629082 CHMP4A charged multivesicular body protein 4A 1.06994331E-09 1.2404825E-08 -2.4645 0.3321 0.3321 0.3321 0.3970 0.3970 0.39708411 EEA1 early endosome antigen 1 1.5156799E-12 6.02776456E-11 -2.4649 3.0167 3.0844 2.0358 2.5449 3.8377 2.4674114770 PGLYRP2 peptidoglycan recognition protein 2 0.00301243896 0.007493175292 -2.4667 0.7660 0.6590 0.4176 0.3572 0.1500 0.19288745 ADAM23 ADAM metallopeptidase domain 23 0.00219501598 0.005636218667 -2.4679 0.5324 0.9149 0.7518 0.6534 0.4892 0.55506202 RPS8 ribosomal protein S8 2.02896592E-10 3.01899555E-09 -2.4682 0.3841 2.0467 1.4891 0.1097 2.9937 0.60126654 SOS1 son of sevenless homolog 1 (Drosophila) 6.23652023E-10 7.8588757E-09 -2.4690 1.2346 1.4765 1.0221 1.0724 1.3802 1.3887114899 C1QTNF3 C1q and tumor necrosis factor related protein 3 0.00202644323 0.005248358721 -2.4696 0.0963 0.0683 0.2833 0.2110 0.1220 0.22086019 RLN2 relaxin 2 0.00029059277 0.000905321582 -2.4713 1.7219 1.6544 1.4536 1.5792 1.7175 1.5113114819 CROCCP3 KIAA1922 protein 2.65962178E-05 0.000102072273 -2.4720 0.0732 0.2599 0.4956 0.0893 0.0487 0.37514494 MT1F metallothionein 1F 9.01611438E-07 4.7407897E-06 -2.4731 1.7315 2.5580 2.1357 1.4275 1.6779 1.7621138241 C9orf85 chromosome 9 open reading frame 85 4.77288765E-10 6.25611213E-09 -2.4751 2.4717 8.3832 1.1702 1.1951 4.7102 1.070225777 SUN2 Sad1 and UNC84 domain containing 2 1.08334936E-06 5.60446191E-06 -2.4752 1.7856 1.5272 1.4488 1.6200 1.0133 1.782554816 ZNF280D zinc finger protein 280D 4.39947513E-08 3.191235E-07 -2.4760 0.4950 0.4850 0.4177 0.5089 0.7897 0.5910125150 ZSWIM7 zinc finger, SWIM-type containing 7 2.43991729E-07 1.47281694E-06 -2.4770 1.9159 9.5556 3.1388 1.5514 9.8629 3.244425937 WWTR1 WW domain containing transcription regulator 1 0.02032874327 0.040009349095 -2.4780 0.1184 0.5108 0.7306 0.3410 0.3588 0.382884945 ABHD13 abhydrolase domain containing 13 2.05424118E-10 3.05411675E-09 -2.4794 1.5885 1.8162 2.2528 1.9035 0.3929 0.5017151393 RMDN2 regulator of microtubule dynamics 2 1.85587009E-05 7.36703417E-05 -2.4795 0.7646 0.7991 0.7821 0.7110 1.0788 0.8425286190 LOC286190 hypothetical protein LOC286190 0.00678214687 0.01537320278 -2.4829 0.0683 0.1759 0.2896 1.3731 0.0932 0.160255529 TMEM55A transmembrane protein 55A 8.85615495E-08 5.94706591E-07 -2.4850 1.9315 1.8699 1.8087 1.4105 1.3420 1.6820399815 LOC399815 similar to chromosome 10 open reading frame 88; Em 2.1776767E-05 8.51498153E-05 -2.4853 0.1997 0.5264 0.6197 0.7927 2.9556 0.80861666 DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.41918096E-10 2.21634824E-09 -2.4862 2.3452 2.5235 1.7436 2.4720 3.2708 2.7902757 TMEM50B transmembrane protein 50B 1.58324152E-09 1.74271018E-08 -2.4866 2.1172 1.9991 1.8251 2.0454 2.7190 2.5928115352 FCRL3 Fc receptor-like 3 0.00120352647 0.003289087004 -2.4904 0.2981 0.2677 0.3062 0.2830 0.0909 0.22882052 EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.92806684E-05 7.6188662E-05 -2.4909 0.6489 0.6737 0.7298 0.4802 0.5593 0.56769881 TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 0.001151747 0.003161767009 -2.4917 0.8982 2.0214 1.8129 0.8818 1.8174 2.157455857 PLK1S1 polo-like kinase 1 substrate 1 1.90885722E-08 1.52042891E-07 -2.4919 1.3966 1.2967 1.1981 1.1632 1.0734 1.02175788 PTPRC protein tyrosine phosphatase, receptor type, C 6.83983149E-10 8.46730359E-09 -2.4926 2.7752 1.8292 1.3804 2.6657 2.6322 1.17356165 RPL35A ribosomal protein L35a 6.24507905E-11 1.1264569E-09 -2.4942 5.1878 4.9417 3.2283 2.3777 4.0281 1.56469522 SCAMP1 secretory carrier membrane protein 1 6.22680137E-11 1.12538194E-09 -2.4962 0.7395 0.8108 0.6936 1.1025 1.3927 1.00134126 MANBA mannosidase, beta A, lysosomal 7.36085834E-06 3.18337523E-05 -2.4963 1.9379 1.9301 2.2935 1.9357 2.0024 2.838925948 KBTBD2 kelch repeat and BTB (POZ) domain containing 2 2.15712347E-12 7.84043727E-11 -2.4970 2.2308 1.6901 2.1538 2.3029 2.6881 2.9111

55198 APPL2 4.05604531E-11 7.90950479E-10 -2.4975 1.7897 2.2154 1.3971 1.4550 1.6684 1.18178620 NPFF neuropeptide FF-amide peptide precursor 0.00115592036 0.003170365781 -2.4981 0.3966 0.1210 0.3171 0.2505 0.5376 0.224451277 DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27 2.40829344E-05 9.31308734E-05 -2.5008 1.5666 3.2918 2.3611 1.2211 3.9735 2.425511329 STK38 serine/threonine kinase 38 1.84704173E-09 1.98758225E-08 -2.5010 2.6682 2.2571 1.6188 2.1951 1.5756 1.2690

3738 KCNA3 potassium voltage-gated channel, shaker-related subfamily, member 3 7.81750119E-07 4.16933397E-06 -2.5010 0.6508 2.6797 1.2197 0.8343 2.8534 2.43648434 RECK reversion-inducing-cysteine-rich protein with kazal motifs 4.5647543E-08 3.29282237E-07 -2.5014 1.3202 1.1133 0.5925 1.0267 1.2309 0.753979993 ELOVL7 ELOVL fatty acid elongase 7 0.01377163477 0.028546263238 -2.5018 0.6281 0.4890 0.7291 0.2537 0.5730 0.6181100505738 MIR4458HG MIR4458 host gene (non-protein coding) 1.12624584E-05 4.67699183E-05 -2.5031 14.7846 1.3628 1.9607 6.1702 0.3932 0.34104297 KMT2A lysine (K)-specific methyltransferase 2A 4.36466689E-14 4.71406292E-12 -2.5031 0.9599 1.0470 0.6100 1.1055 1.2947 1.1298401474 SAMD12 sterile alpha motif domain containing 12 1.78072576E-05 7.09494573E-05 -2.5032 1.2139 1.0455 1.4345 1.6192 1.8974 1.1102100093630 SNHG8 small nucleolar RNA host gene 8 (non-protein coding) 5.74774764E-09 5.30080124E-08 -2.5043 1.2054 4.2939 1.9279 1.0322 1.7151 0.798191612 CHURC1 churchill domain containing 1 1.54245815E-11 3.67454958E-10 -2.5044 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706204 RPS10 ribosomal protein S10 1.53353698E-10 2.37062502E-09 -2.5044 16.8205 8.6784 1.8782 15.9637 2.3539 1.719655454 CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 7.23387595E-08 4.96907449E-07 -2.5072 2.1716 3.9850 2.1037 2.1013 5.0522 3.584626071 FAM127B family with sequence similarity 127, member B 1.26395349E-06 6.44031181E-06 -2.5080 1.3130 1.0215 1.6303 1.4393 1.1948 2.30916207 RPS13 ribosomal protein S13 8.9929598E-12 2.37455725E-10 -2.5087 2.5718 3.1234 2.4658 2.3113 5.6879 4.01962207 FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.01809485367 0.036177827578 -2.5093 0.7895 0.3668 0.4575 0.8174 0.2424 0.3428

23347 SMCHD1 7.08662904E-15 1.43874317E-12 -2.5106 0.5140 0.6696 0.5512 1.2063 1.1667 1.2848196385 DNAH10 dynein, axonemal, heavy chain 10 0.00121938647 0.003327453638 -2.5107 0.4463 0.7858 0.3738 0.4236 0.5944 0.3720400961 PAIP2B poly(A) binding protein interacting protein 2B 3.48894631E-06 1.61720008E-05 -2.5109 1.4910 1.7057 2.0069 1.4346 1.6191 2.17704666 NACA nascent polypeptide-associated complex alpha subunit 2.85321673E-12 9.70837544E-11 -2.5116 2.2895 2.1269 1.6469 2.1221 2.4504 2.31634629 MYH11 myosin, heavy chain 11, smooth muscle 2.45667657E-05 9.48413147E-05 -2.5132 0.2216 0.2428 0.2429 0.3283 0.1025 0.2629594839 SNORA33 small nucleolar RNA, H/ACA box 33 7.36322587E-07 3.95127351E-06 -2.5141 2.9504 3.4195 1.6583 2.0947 4.4208 1.1768677767 SCARNA7 small Cajal body-specific RNA 7 0.00181251159 0.004739297617 -2.5143 0.1724 0.0396 0.1149 0.2846 0.1064 0.116257763 ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 7.83059745E-08 5.33683986E-07 -2.5146 44.5372 2.0482 8.7066 15.3881 0.5760 3.902710818 FRS2 fibroblast growth factor receptor substrate 2 5.70495271E-12 1.70050401E-10 -2.5148 2.1250 3.8473 1.7664 2.2291 4.5125 1.948923604 DAPK2 death-associated protein kinase 2 0.02510217596 0.048022925261 -2.5150 1.2837 0.5571 1.6625 0.8800 0.4206 1.10641646 AKR1C2 aldo-keto reductase family 1, member C2 0.01534258798 0.031361423821 -2.5161 0.1523 0.0948 0.1370 0.2187 0.1530 0.1640399744 LINC00999 long intergenic non-protein coding RNA 999 2.12187366E-05 8.31993035E-05 -2.5194 0.0592 0.0611 0.1270 0.3375 0.0178 0.342326122 EPC2 enhancer of polycomb homolog 2 (Drosophila) 4.59490419E-12 1.42785866E-10 -2.5196 1.2294 2.6725 1.7458 1.7836 5.0361 3.341992249 LOC92249 uncharacterized LOC92249 3.73874847E-06 1.7211996E-05 -2.5200 2.5467 4.6855 2.0515 2.1213 4.1985 2.38635583 PRKCH protein kinase C, eta 9.16700093E-09 7.90768148E-08 -2.5206 0.9341 1.1806 1.0903 0.9785 1.2122 1.0652100132352 LOC100132352 FSHD region gene 1 pseudogene 5.0935013E-09 4.78689287E-08 -2.5208 1.5355 1.4333 1.1778 1.6174 2.3422 1.798150865 HEBP1 heme binding protein 1 2.47590557E-05 9.55634697E-05 -2.5213 1.8449 4.3957 1.7108 0.5980 3.1358 0.444025976 TIPARP TCDD-inducible poly(ADP-ribose) polymerase 5.03339735E-10 6.52734112E-09 -2.5225 1.2682 1.9341 2.1023 1.1540 1.1359 1.5534400892 BCRP2 FLJ42953 protein 2.24855649E-06 1.08405341E-05 -2.5227 0.2755 0.3372 0.5826 0.0806 0.1569 0.2057

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12

suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 4

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

structural maintenance of chromosomes flexible hinge domain containing 1

10769 PLK2 polo-like kinase 2 0.00127490962 0.003462949108 -2.5234 1.3730 2.2184 1.6084 1.0488 2.0756 1.514256241 SUSD2 sushi domain containing 2 0.00221441174 0.005680433997 -2.5241 0.0428 0.0458 0.2397 0.1080 0.0215 0.116179635 CCDC121 coiled-coil domain containing 121 0.00509765106 0.011979971726 -2.5241 0.3321 0.3321 0.3321 0.3970 0.3970 0.397011230 PRAF2 PRA1 domain family, member 2 1.92301708E-10 2.87304727E-09 -2.5250 0.5890 1.1374 0.9666 0.6889 1.7403 0.89559651 PLCH2 phospholipase C, eta 2 3.27094375E-05 0.00012325569 -2.5252 0.1099 0.1432 0.0863 0.0574 0.1023 0.137810930 APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 0.00013169446 0.00044047613 -2.5273 1.4956 0.7398 0.8922 0.9760 0.4341 0.6857100129534 LOC100129534 small nuclear ribonucleoprotein polypeptide N pseudogene 0.00610791449 0.014006502705 -2.5290 0.0312 0.1497 0.0800 0.0628 0.0768 0.1047345222 MSANTD1 Myb/SANT-like DNA-binding domain containing 1 0.0169583309 0.034189851287 -2.5294 0.0720 0.4107 0.2108 0.1488 0.0099 0.2641387895 LINC00944 long intergenic non-protein coding RNA 944 0.01954549525 0.03867611969 -2.5318 0.2999 0.2217 0.6612 0.3260 0.1699 0.36187431 VIM vimentin 1.43326673E-05 5.81840695E-05 -2.5348 3.4272 2.5623 1.5045 3.4292 1.9502 2.2101687 KLF9 Kruppel-like factor 9 4.27433903E-09 4.11706499E-08 -2.5353 1.3858 1.1851 1.3689 1.2882 1.0415 1.648723118 TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 3.00898707E-14 3.71487918E-12 -2.5367 1.1432 1.3034 1.0721 1.1223 1.7909 1.1625348254 CCDC144CP KIAA0565 protein related gene 2.37123607E-05 9.18144212E-05 -2.5375 0.6021 1.1794 1.8956 0.6131 1.1952 1.04703904 LAIR2 leukocyte-associated immunoglobulin-like receptor 2 0.00043830337 0.001309891908 -2.5383 1.0808 0.7265 1.0293 0.8619 0.4379 0.49285243 ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.47029036E-06 1.18221963E-05 -2.5392 1.5055 1.5668 1.0058 1.3592 1.3732 1.1582387082 SUMO4 small ubiquitin-like modifier 4 0.00269367411 0.006776650601 -2.5419 0.0922 0.2298 0.1349 0.3203 0.1364 0.2682126375 ZNF792 zinc finger protein 792 1.8487952E-08 1.47645043E-07 -2.5419 3.2635 2.7099 1.3612 2.8169 3.3171 1.797410597 TRAPPC2P1 trafficking protein particle complex 2 pseudogene 1 1.0406527E-05 4.35320653E-05 -2.5427 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706134 RPL10 ribosomal protein L10 8.58870459E-10 1.02704719E-08 -2.5433 2.1528 3.3102 1.7213 2.7548 5.8309 3.2569119504 ANAPC16 chromosome 10 open reading frame 104 1.17109643E-11 2.94742065E-10 -2.5438 0.2037 0.2445 0.4239 0.2638 0.2244 0.384823253 ANKRD12 ankyrin repeat domain 12 5.01026796E-11 9.4281788E-10 -2.5440 1.2711 1.7390 1.1410 1.2864 1.7313 1.648810404 CPQ carboxypeptidase Q 2.12646724E-05 8.33615304E-05 -2.5485 0.7664 0.5234 0.9189 0.7216 0.3443 0.75499263 STK17A serine/threonine kinase 17a 7.74792913E-08 5.2824687E-07 -2.5507 1.2175 1.2127 1.1543 1.5330 1.7063 1.843783699 SH3BGRL2 SH3 domain binding glutamic acid-rich protein like 2 0.00422902561 0.010146107653 -2.5518 1.0421 1.2509 1.0772 1.2370 0.7828 0.71097311 UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 2.10440948E-12 7.70576555E-11 -2.5529 2.0422 2.7721 1.5935 1.8275 3.8379 2.3631

6519 SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.02578467559 0.049128007555 -2.5542 0.1175 0.1082 0.2085 0.2914 0.0732 0.284151696 HECA headcase homolog (Drosophila) 1.1434379E-08 9.62362844E-08 -2.5561 1.5553 1.7078 0.8743 1.6038 1.7125 1.3601

286102 TMED10P1 transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 0.00115459223 0.003167674069 -2.5575 0.0607 0.0344 0.0729 0.2515 0.0211 0.213225832 NBPF14 neuroblastoma breakpoint family, member 14 7.20478594E-08 4.95468004E-07 -2.5587 0.0977 0.0772 0.1854 0.3099 0.0874 0.184751526 OSER1 oxidative stress responsive serine-rich 1 2.20332019E-09 2.30250249E-08 -2.5597 4.4660 6.1503 1.1030 1.4141 11.7761 3.564010140 TOB1 transducer of ERBB2, 1 5.29501884E-08 3.75438821E-07 -2.5606 2.7708 1.2464 1.3903 2.1080 1.0144 1.555554823 SWT1 SWT1 RNA endoribonuclease homolog (S. cerevisiae) 8.68599061E-06 3.69609735E-05 -2.5615 1.4976 1.2306 3.1388 2.1379 1.1944 4.604584765 ZNF577 zinc finger protein 577 0.0001060223 0.000362303995 -2.5648 0.3314 0.4379 0.4327 1.6706 0.4271 0.562054557 SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta 4.78934058E-10 6.27317785E-09 -2.5655 3.0257 36.7806 1.4198 3.2512 23.3642 1.4842100130950 LOC100130950 uncharacterized LOC100130950 0.00988137659 0.021415314079 -2.5670 0.6616 1.5545 0.2189 0.3042 0.6370 0.111823321 TRIM2 tripartite motif containing 2 0.00164454889 0.004352432974 -2.5718 1.3386 2.1024 1.0783 1.0374 0.9766 0.76797128 TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.10636609E-07 7.2457065E-07 -2.5725 2.8965 3.5462 2.0889 2.1968 3.9509 2.39646168 RPL37A ribosomal protein L37a 1.95637465E-11 4.4795586E-10 -2.5747 2.9420 1.5111 1.9943 2.7762 1.9196 2.607065110 UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 4.54581748E-14 4.76715125E-12 -2.5769 1.0011 1.6163 0.9948 1.1570 2.0394 1.5597440498 HSBP1L1 heat shock factor binding protein 1-like 1 6.34119381E-07 3.45105631E-06 -2.5776 1.5135 1.4122 1.6743 1.1880 1.6113 1.7915222256 CDHR3 hypothetical protein FLJ23834 0.00194085455 0.00504437318 -2.5801 1.1739 1.0821 0.3752 0.6332 0.4982 0.146711009 IL24 interleukin 24 0.00566647268 0.013124323581 -2.5802 0.6418 0.9489 1.2097 1.2539 0.2973 0.6195114884 OSBPL10 oxysterol binding protein-like 10 0.00665577065 0.015111113483 -2.5823 0.3003 0.0962 0.1892 0.2538 0.1322 0.5128257019 FRMD3 FERM domain containing 3 0.0211568771 0.041462264044 -2.5832 0.0903 0.3442 0.3252 0.1968 0.1148 0.2918387841 RPL13AP20 ribosomal protein L13a pseudogene 20 3.13624059E-11 6.48985143E-10 -2.5833 0.0502 0.1499 0.2699 0.4218 0.0475 0.27982329 FMO4 flavin containing monooxygenase 4 0.00012946973 0.000434386873 -2.5839 1.7505 2.2342 1.0128 1.1149 0.7505 0.582210129 FRY furry homolog (Drosophila) 1.79536693E-06 8.87099637E-06 -2.5913 0.5896 0.6469 0.6599 0.6481 0.6627 0.71156403 SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.00022105102 0.000704156956 -2.5923 0.5414 0.4913 0.3779 0.5199 0.3437 0.35807832 BTG2 BTG family, member 2 3.7336208E-07 2.15615421E-06 -2.5937 3.5327 1.8354 1.6951 8.1402 3.6597 2.528180212 CCDC92 coiled-coil domain containing 92 9.31337041E-11 1.56266211E-09 -2.5953 2.5862 1.3900 1.1253 2.6984 1.5221 1.328710927 SPIN1 spindlin 1 2.57115003E-11 5.57957877E-10 -2.5959 1.3178 1.5955 1.5884 0.8700 1.1793 1.784310349 ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 0.01561277749 0.031838914094 -2.5984 0.0762 0.0985 0.0928 0.1742 0.1956 0.1803837 CASP4 caspase 4, apoptosis-related cysteine peptidase 3.99997463E-08 2.93053474E-07 -2.5998 1.6894 2.7159 1.0160 1.6051 1.7737 0.818426994 RNF11 ring finger protein 11 2.12850831E-11 4.78966796E-10 -2.6023 2.0704 1.4294 2.2886 2.0396 1.9323 2.442580164 FLJ22184 putative uncharacterized protein FLJ22184 0.00921127551 0.020120553041 -2.6044 0.6723 0.6183 1.4282 0.3345 0.3157 0.939955604 LRRC16A leucine rich repeat containing 16A 2.99291593E-08 2.24862499E-07 -2.6051 1.0329 0.9143 1.0016 1.0440 1.0000 0.97714240 MFGE8 milk fat globule-EGF factor 8 protein 6.74442121E-08 4.66972582E-07 -2.6057 1.1860 1.4579 1.4455 1.0513 1.3647 1.3017116151 FAM210B family with sequence similarity 210, member B 9.60489183E-10 1.13226183E-08 -2.6062 0.9307 1.6427 1.1821 0.6222 1.4352 1.249655279 ZNF654 zinc finger protein 654 1.64603707E-13 1.16575152E-11 -2.6066 0.0399 0.0361 0.1106 0.2494 0.0284 0.23238976 WASL Wiskott-Aldrich syndrome-like 6.31557427E-11 1.13469197E-09 -2.6085 2.7142 3.7532 1.4199 2.6858 3.7804 2.526623228 PLCL2 phospholipase C-like 2 3.33701721E-11 6.78618383E-10 -2.6089 1.1514 1.7148 0.7823 1.7958 2.1712 1.009629066 ZC3H7A zinc finger CCCH-type containing 7A 1.37805657E-10 2.16136048E-09 -2.6091 0.8392 0.6423 0.5051 0.8961 0.8412 0.747053346 TM6SF1 transmembrane 6 superfamily member 1 0.0018403045 0.004805093426 -2.6146 0.5746 0.4292 1.0327 0.5207 0.3504 1.2517645843 TMEM14E transmembrane protein 14E 0.00175741876 0.004613066459 -2.6149 0.8896 0.4811 0.2962 0.5469 0.3750 0.221993627 TBCK TBC1 domain containing kinase 1.26965992E-09 1.44715518E-08 -2.6160 1.1538 2.9846 0.6488 0.8105 4.1323 0.368054704 PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 2.11367423E-09 2.22149559E-08 -2.6180 1.0997 1.7156 1.5341 1.0757 1.5087 1.372257132 CHMP1B chromatin modifying protein 1B 4.26531797E-10 5.67632119E-09 -2.6204 3.3506 6.4361 1.6926 3.8174 7.2593 2.18154707 NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 1.05682468E-09 1.22839062E-08 -2.6205 1.4079 0.4629 0.8337 2.0171 0.3708 0.7458353088 ZNF429 zinc finger protein 429 1.02859852E-05 4.31166603E-05 -2.6230 1.7860 1.4307 1.2200 2.1032 1.7741 1.968255074 OXR1 oxidation resistance 1 1.24360347E-12 5.10631968E-11 -2.6232 1.5845 1.3980 0.9253 1.2867 1.2576 1.029264131 XYLT1 xylosyltransferase I 2.45098244E-09 2.52590813E-08 -2.6246 1.7262 1.1075 1.6391 1.4064 0.8338 1.5162730094 C16orf52 similar to CG14182-PA 1.65601814E-08 1.33716836E-07 -2.6267 2.5641 3.9898 1.9543 2.7532 4.7670 2.41435732 PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.00096722707 0.002696136233 -2.6268 3.2207 1.2447 2.2493 2.6030 0.9909 2.5510284723 SLC25A34 solute carrier family 25, member 34 0.00576228015 0.013315844549 -2.6285 0.0441 0.0186 0.0788 0.0859 0.0095 0.1785653687 FAM226B family with sequence similarity 226, member B (non-protein coding) 8.0059418E-06 3.43552298E-05 -2.6296 1.3971 1.9006 1.5931 1.5268 1.9779 1.2258285331 CCDC66 coiled-coil domain containing 66 6.4979166E-10 8.12662095E-09 -2.6300 2.2485 1.3845 0.8157 2.4699 2.1043 1.16254850 CNOT4 CCR4-NOT transcription complex, subunit 4 1.25886841E-15 4.89405183E-13 -2.6302 3.6756 2.5254 2.3285 3.5672 4.5933 3.6845

634 CEACAM1 0.00028325557 0.000884844444 -2.6319 1.1465 0.9447 1.3305 0.7748 0.6003 0.809564091 POPDC2 popeye domain containing 2 0.00103065651 0.002854147024 -2.6323 0.1502 0.2236 0.3011 0.3118 0.2202 0.283110077 TSPAN32 tetraspanin 32 5.28944666E-06 2.36016531E-05 -2.6329 0.4916 0.7920 0.8538 0.2816 0.7335 0.50935004 ORM1 orosomucoid 1 0.01141951358 0.024251203171 -2.6337 0.0419 0.0919 0.1854 0.1997 0.0104 0.3367348174 CLEC18A secretory protein LOC348174 0.00659895233 0.015002619993 -2.6339 0.0314 0.0431 0.0846 0.3627 0.0440 0.07647696 ZNF137P zinc finger protein 137, pseudogene 6.77190649E-05 0.000240966456 -2.6358 0.0624 0.0389 0.1975 0.3715 0.0701 0.5878654817 NCF1C neutrophil cytosolic factor 1C pseudogene 0.00456958985 0.010866156394 -2.6366 0.3088 0.4065 0.4464 0.2233 0.2840 0.29216622 SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.01529995882 0.031295292455 -2.6382 1.3307 1.0152 0.8902 1.0523 0.5246 0.7405389765 LOC389765 kinesin family member 27 pseudogene 5.12789891E-06 2.29424508E-05 -2.6394 2.6188 1.3487 1.6899 1.9428 1.3033 1.784758508 KMT2C lysine (K)-specific methyltransferase 2C 8.02534281E-14 6.88446309E-12 -2.6396 0.6054 0.5841 0.6760 0.7281 0.8483 1.54261577 CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.00576021903 0.013312765253 -2.6398 0.2025 0.1850 0.2366 0.3089 0.3602 0.302023469 PHF3 PHD finger protein 3 2.86116101E-13 1.76618696E-11 -2.6398 1.6360 1.4568 0.9554 1.2902 1.6118 1.31365924 RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 6.03800832E-07 3.30814057E-06 -2.6403 1.1509 1.9615 0.7729 1.3510 1.3592 1.194751185 CRBN cereblon 4.69127009E-10 6.15796603E-09 -2.6463 1.9142 2.4938 1.3216 1.9824 3.1286 1.7730

80853 JHDM1D 1.44951198E-09 1.61005975E-08 -2.6493 0.6836 1.9958 0.6315 0.7991 2.1284 1.38393903 LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.00101036949 0.002803197575 -2.6499 2.9346 1.9312 1.7330 2.2006 1.5339 1.0522153684 LOC153684 uncharacterized LOC153684 0.00180055922 0.004712924591 -2.6500 3.4780 3.0721 2.8094 3.4750 2.7183 4.4723136895 C7orf31 chromosome 7 open reading frame 31 8.6848888E-06 3.69609735E-05 -2.6523 1.2706 1.8705 2.3273 1.0346 1.6658 1.8280

5303 PIN4 2.07966913E-08 1.64036465E-07 -2.6532 2.2122 1.8341 2.1896 2.7173 2.2287 2.883022849 CPEB3 cytoplasmic polyadenylation element binding protein 3 3.86075607E-07 2.21835645E-06 -2.6543 1.3139 6.1309 0.9862 1.1863 2.8718 0.759857577 KIAA1407 KIAA1407 1.70310039E-05 6.81389322E-05 -2.6550 0.7000 0.5114 3.4039 0.6971 3.7929 2.1999200558 APLF chromosome 2 open reading frame 13 3.34137741E-08 2.48387502E-07 -2.6559 0.3772 0.5665 0.5641 0.3723 0.5736 0.33944330 MN1 meningioma (disrupted in balanced translocation) 1 0.00224378039 0.005746664773 -2.6581 1.0160 1.5517 0.6183 0.7817 1.0655 0.5327201627 DENND6A family with sequence similarity 116, member A 1.18568954E-11 2.9718682E-10 -2.6583 1.2845 2.1777 1.4577 1.5165 2.7620 2.285984449 ZNF333 zinc finger protein 333 3.02833341E-08 2.27149869E-07 -2.6586 1.7892 3.4936 1.5845 1.6662 4.2051 1.897925890 ABI3BP ABI family, member 3 (NESH) binding protein 0.01105524229 0.023573507657 -2.6607 0.1207 0.1507 0.1323 0.1764 0.0396 0.1599114908 TMEM123 transmembrane protein 123 8.68626531E-12 2.31701372E-10 -2.6608 1.6416 1.8178 1.7080 1.4666 3.4863 2.072691181 NUP210L nucleoporin 210kDa-like 0.000525275 0.001545091902 -2.6615 0.4811 0.5135 0.5698 0.4433 0.4559 0.37722334 AFF2 AF4/FMR2 family, member 2 0.00011402508 0.000386973683 -2.6616 1.2864 0.8858 0.8426 1.0460 1.2133 0.94929324 HMGN3 high mobility group nucleosomal binding domain 3 4.4781514E-09 4.28626413E-08 -2.6620 0.5902 0.6783 0.5724 0.5552 0.1837 0.402754674 LRRN3 leucine rich repeat neuronal 3 3.80518454E-06 1.74782132E-05 -2.6638 2.3639 2.1044 1.7461 2.6727 2.3708 2.3490100288486 DDX11L9 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 9 0.00555129779 0.012886966478 -2.6656 0.1160 0.4449 0.2110 0.2319 0.0856 0.2876726 CAPN5 calpain 5 3.53818197E-05 0.000132750844 -2.6684 0.5533 0.6464 0.9047 0.4100 0.9567 0.84722313 FLI1 Fli-1 proto-oncogene, ETS transcription factor 1.6605996E-11 3.89505467E-10 -2.6700 1.6068 2.2732 1.7631 1.3656 1.9786 1.70144192 MDK midkine (neurite growth-promoting factor 2) 2.62114202E-05 0.000100701234 -2.6718 1.1455 2.9600 1.3742 0.5755 1.9625 0.8611338817 LOC338817 uncharacterized LOC338817 0.02282746314 0.044231538339 -2.6731 1.3999 0.6286 0.8393 0.5955 0.7324 0.44667739 ZNF185 zinc finger protein 185 (LIM domain) 0.00050052211 0.001477947639 -2.6732 0.4951 0.7270 0.8085 0.3973 0.8486 0.8361283876 LINC00921 hypothetical protein FLJ39639 8.3438323E-06 3.56461313E-05 -2.6744 1.4152 0.3304 0.9118 0.3712 0.9951 0.388185315 PAQR8 progestin and adipoQ receptor family member VIII 4.08633413E-08 2.98781501E-07 -2.6750 1.4609 2.3559 2.4122 1.4992 3.3416 3.01737352 UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 4.8385756E-06 2.17652519E-05 -2.6758 0.8225 0.5870 1.0252 0.4852 0.2641 0.30303275 PRMT2 protein arginine methyltransferase 2 2.45038354E-10 3.56476178E-09 -2.6766 1.0260 1.3000 1.3661 0.8896 1.3036 1.3546153733 CCDC112 coiled-coil domain containing 112 1.79954153E-05 7.16522616E-05 -2.6786 1.6630 2.6481 1.2512 1.0913 1.8954 1.081626751 SH3YL1 SH3 and SYLF domain containing 1 7.81921035E-09 6.87217949E-08 -2.6788 0.3345 0.3816 0.3726 0.3836 0.4634 0.329765981 CAPRIN2 caprin family member 2 2.64384542E-07 1.58106339E-06 -2.6795 0.6088 0.7596 0.7852 0.4961 0.6293 0.6062

3674 ITGA2B 0.0062333206 0.014265435129 -2.6825 0.1355 0.1160 0.3245 0.1201 0.1665 0.28289987 HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 9.62421847E-11 1.60304211E-09 -2.6846 1.6089 1.0336 0.3124 4.7034 2.8472 1.55159028 RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 0.01131427951 0.024055680147 -2.6861 0.2997 1.0148 0.4501 0.3659 0.3950 0.23255080 PAX6 paired box 6 4.48164071E-06 2.02694404E-05 -2.6867 0.7759 1.0784 1.0456 0.5645 0.9213 0.61933115 HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.00169264473 0.004463559617 -2.6885 0.5421 0.3966 0.4421 0.4737 0.4230 0.5391729220 FLJ45513 uncharacterized LOC729220 1.0922862E-05 4.54940813E-05 -2.6905 0.3808 0.1406 0.4243 0.1534 0.0746 0.3974143684 FAM76B family with sequence similarity 76, member B 2.55571959E-11 5.55929861E-10 -2.6908 1.6181 3.1850 2.6891 1.6068 4.0272 5.632310742 RAI2 retinoic acid induced 2 0.00140862602 0.003786174565 -2.6946 1.0019 2.3331 1.7194 0.6641 2.8601 1.1782283551 C14orf182 hypothetical protein LOC283551 5.47376174E-05 0.000198163205 -2.6955 0.2395 0.3043 0.4050 0.2828 0.0659 0.32608557 TCAP titin-cap 0.0005599863 0.001636084044 -2.6960 0.0607 0.2915 0.2031 0.0785 0.1413 0.205366035 SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 4.5127099E-05 0.000166008124 -2.6984 2.0732 1.6963 1.3972 1.7764 1.6407 1.5355100288432 IL10RB-AS1 IL10RB antisense RNA 1 (head to head) 0.00035898406 0.001095051194 -2.7006 1.2609 9.1274 1.1078 0.6244 2.0486 0.2969148696 LOC148696 uncharacterized LOC148696 0.00059441249 0.001726890749 -2.7007 0.3015 0.3476 0.2803 0.3689 0.4942 0.318592973 LINC00950 long intergenic non-protein coding RNA 950 0.01304773031 0.027249757474 -2.7015 0.1341 0.0378 0.2303 0.2181 0.0271 0.12326934 TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.97382978E-05 7.78119045E-05 -2.7022 0.9226 0.9302 0.6177 0.8886 0.7297 0.5903122773 KLHDC1 kelch domain containing 1 3.40303271E-06 1.58058499E-05 -2.7028 2.4772 1.9576 2.0070 1.9752 1.9702 2.064151655 RASD1 RAS, dexamethasone-induced 1 0.00928663503 0.020277891414 -2.7036 1.7251 2.1677 1.6620 1.5211 1.4140 1.6425

carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)

jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)

protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

54414 SIAE sialic acid acetylesterase 2.21625619E-06 1.07045818E-05 -2.7044 0.2275 0.3222 0.5120 0.1855 1.0651 0.163384081 NSRP1 coiled-coil domain containing 55 5.31142109E-12 1.60945748E-10 -2.7055 0.3117 0.7268 0.2698 0.3678 0.3806 0.525056978 PRDM8 PR domain containing 8 9.24983591E-06 3.9159639E-05 -2.7055 1.4857 2.0059 2.0636 1.2708 1.4400 1.7941121665 SPPL3 signal peptide peptidase like 3 1.89846514E-13 1.30408854E-11 -2.7064 0.6303 0.6991 0.8241 0.5712 1.2214 0.9062100130298 LOC100130298 hCG1816373-like 3.25608109E-05 0.000122771593 -2.7076 1.1331 1.2878 1.0318 1.1745 0.8187 1.0734100132724 DCAF13P3 DDB1 and CUL4 associated factor 13 pseudogene 3 0.00029483914 0.000917299626 -2.7140 0.1431 0.0709 0.0655 0.2042 0.0262 0.179384498 FAM120B family with sequence similarity 120B 1.58475249E-15 5.36233287E-13 -2.7168 1.4203 1.6643 1.4135 1.3176 1.3808 1.335790634 N4BP2L1 NEDD4 binding protein 2-like 1 1.90928672E-07 1.18460058E-06 -2.7172 1.5657 1.0796 1.4163 1.4856 1.3806 2.038751192 CKLF chemokine-like factor 8.38334366E-09 7.2943074E-08 -2.7231 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970317662 FAM149B1 KIAA0974 9.70697624E-10 1.14131986E-08 -2.7232 0.3175 0.5530 0.7015 1.0274 0.4843 0.150492106 OXNAD1 oxidoreductase NAD-binding domain containing 1 3.4506489E-08 2.55574612E-07 -2.7248 0.5061 1.6132 0.5295 0.6292 0.9990 0.3751414328 IDNK idnK, gluconokinase homolog (E. coli) 2.37750193E-06 1.14080135E-05 -2.7251 1.6521 2.3021 1.5869 0.9876 2.6226 2.27516166 RPL36AL ribosomal protein L36a-like 4.75858904E-12 1.4659642E-10 -2.7266 17.4889 17.9606 2.7855 17.1126 12.7464 3.38649397 NMT2 N-myristoyltransferase 2 5.23754349E-07 2.90635122E-06 -2.7267 1.5445 2.2639 1.1710 1.1335 1.9429 1.1077

378938 MALAT1 1.08261124E-05 4.51219722E-05 -2.7272 2.9472 4.9321 2.2682 2.4730 6.1010 2.824255843 ARHGAP15 Rho GTPase activating protein 15 8.69233075E-11 1.47471001E-09 -2.7282 1.8552 1.4173 1.0086 1.6771 1.1815 0.909723089 PEG10 paternally expressed 10 0.00113577294 0.003122444335 -2.7318 1.8793 2.7424 2.8812 1.3701 1.9551 2.9383445347 TARP TCR gamma alternate reading frame protein 0.00033280965 0.001023756017 -2.7339 0.9947 0.5071 0.5304 1.1328 0.5061 0.517623641 LDOC1 leucine zipper, down-regulated in cancer 1 4.38640673E-08 3.18428382E-07 -2.7340 0.9703 1.0331 1.3790 0.9982 1.2982 1.0110283624 LINC00641 hypothetical protein LOC283624 4.15428593E-09 4.02240113E-08 -2.7368 0.1418 0.1764 0.1733 0.1961 0.0337 0.155629072 SETD2 SET domain containing 2 3.71220462E-14 4.23933768E-12 -2.7374 1.2071 1.4804 0.7341 1.3909 2.1237 0.8551388799 FAM209B family with sequence similarity 209, member B 0.00034811365 0.001065449358 -2.7397 0.2069 0.1749 0.2419 0.3013 0.2070 0.279826959 HBP1 HMG-box transcription factor 1 4.02143814E-11 7.87563963E-10 -2.7399 1.5576 2.3847 1.5297 1.4594 2.5243 1.5617100505483 PRKAG2-AS1 PRKAG2 antisense RNA 1 4.22491237E-06 1.91842939E-05 -2.7404 6.0819 17.1849 0.0959 10.8244 7.2518 0.4907401629 FAM224B family with sequence similarity 224, member B (non-protein coding) 0.0079784812 0.017728664546 -2.7414 1.1544 0.8238 0.4411 0.9286 0.6701 0.5498400668 PRSS57 protease, serine, 57 0.00603939956 0.013878390771 -2.7440 0.3715 0.5050 0.3691 0.0981 0.2687 0.2171339804 C2orf74 hypothetical gene supported by AK075484; BC014578 7.54490843E-09 6.6663717E-08 -2.7450 0.2405 0.6727 0.2743 0.4802 0.1449 0.17105071 PARK2 parkin RBR E3 ubiquitin protein ligase 0.00701593166 0.015824602306 -2.7450 0.1358 0.1032 0.2035 0.2469 0.1149 0.2951100126270 FMR1-AS1 FMR1 antisense RNA 1 0.00485630349 0.011468835131 -2.7468 0.5919 0.6576 0.2376 0.4031 0.4107 0.126192482 BBIP1 hypothetical protein LOC92482 1.88437412E-11 4.34738434E-10 -2.7490 2.8225 1.7014 1.9073 2.2050 1.4493 1.699829108 PYCARD PYD and CARD domain containing 0.00018514261 0.000599490656 -2.7495 1.5648 1.2491 1.1719 1.0871 0.5155 0.808651070 NOSIP nitric oxide synthase interacting protein 7.33916302E-09 6.50976634E-08 -2.7498 1.8773 1.8576 2.0499 1.1792 2.6569 1.945227018 NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 2.48752481E-08 1.91619112E-07 -2.7503 1.1373 1.2848 0.9492 1.2839 1.1908 0.9480400818 NBPF9 neuroblastoma breakpoint family, member 9 1.48714842E-08 1.21731422E-07 -2.7510 0.3658 0.2999 0.3784 0.5215 0.4140 0.413284281 C2orf88 hypothetical protein MGC13057 0.00204265966 0.005287360432 -2.7534 0.4444 0.4594 0.3958 0.5021 0.2639 0.3231151056 PLB1 phospholipase B1 0.00187947933 0.004898280748 -2.7550 0.6255 0.4612 0.4661 0.6397 0.3216 0.39097096 TLR1 toll-like receptor 1 0.0213193741 0.041725321717 -2.7614 3.3580 4.2312 1.7415 2.9625 2.3903 1.08597220 TRPC1 transient receptor potential cation channel, subfamily C, member 1 4.57009788E-06 2.06184762E-05 -2.7624 0.5338 1.1629 0.7018 0.4706 0.9442 0.92651740 DLG2 discs, large homolog 2 (Drosophila) 0.00781913647 0.017412707077 -2.7628 0.5102 0.4090 0.4386 0.4853 0.3957 0.41377626 ZNF75D zinc finger protein 75D 5.0091933E-09 4.71793711E-08 -2.7636 1.6157 0.9700 1.4789 1.5115 1.1972 1.558811148 HHLA2 HERV-H LTR-associating 2 0.00779584901 0.017371433296 -2.7652 0.6019 0.9495 1.4734 0.5157 0.8865 0.6984728392 LOC728392 uncharacterized LOC728392 3.37821902E-05 0.000127009913 -2.7652 0.9482 1.5659 1.1518 0.7379 1.6602 0.92884588 MUC6 mucin 6, oligomeric mucus/gel-forming 0.00064356314 0.001854468645 -2.7654 0.0185 0.0295 0.0243 0.0831 0.0095 0.1847348378 FAM159A hypothetical protein MGC52498 1.28744548E-07 8.28900768E-07 -2.7656 2.4925 2.1908 1.7419 2.1492 2.1524 1.06042033 EP300 E1A binding protein p300 5.0564597E-14 5.12601222E-12 -2.7686 2.0931 2.7315 2.2004 1.0412 1.6428 2.5890206412 C6orf163 chromosome 6 open reading frame 163 0.00335649373 0.008243259875 -2.7708 0.1441 0.1470 0.1928 0.4201 0.0545 0.24553397 ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00347384747 0.008504038189 -2.7722 2.4789 3.6897 2.8414 1.7249 1.5746 2.4352

123720 WHAMM 3.79856294E-09 3.71957889E-08 -2.7733 1.7553 1.0530 1.0431 1.8509 1.1087 1.24047076 TIMP1 TIMP metallopeptidase inhibitor 1 4.74144191E-05 0.000173722933 -2.7737 1.3435 2.1608 2.1239 0.7035 0.7028 0.8931

64332 NFKBIZ 7.24128028E-11 1.27108627E-09 -2.7740 2.6489 4.3720 2.3482 2.3739 2.8859 2.13835150 PDE7A phosphodiesterase 7A 1.97886813E-08 1.56867152E-07 -2.7741 1.6652 1.6811 1.2300 1.7354 2.6485 2.17652810 SFN stratifin 0.00279146863 0.006992831744 -2.7741 0.2038 0.3320 0.7337 0.1182 0.6361 0.33505926 ARID4A AT rich interactive domain 4A (RBP1-like) 9.20020299E-14 7.47138262E-12 -2.7754 0.7562 7.4405 0.5892 0.7025 5.5445 1.32687351 UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.86778472E-09 2.00872056E-08 -2.7757 2.1096 3.5317 1.9252 2.6764 5.1784 2.8042115330 GPR146 G protein-coupled receptor 146 2.64273603E-06 1.25423565E-05 -2.7772 0.1351 0.5609 0.2996 0.1186 0.2547 0.371151170 HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 4.29327368E-07 2.43547646E-06 -2.7777 2.4680 2.6434 2.0753 2.7187 3.4098 2.28006227 RPS21 ribosomal protein S21 2.21794496E-12 7.97761619E-11 -2.7783 1.8419 3.0133 1.7923 1.5497 6.0751 2.80465450 POU2AF1 POU class 2 associating factor 1 0.00016178274 0.000530317274 -2.7785 1.3210 3.6547 1.7544 0.7927 1.5246 1.0487100132101 HERC2P7 hect domain and RLD 2 pseudogene 7 0.00351382395 0.008593841694 -2.7785 0.0219 0.0669 0.1835 0.1459 0.0353 0.21337348 UPK1B uroplakin 1B 0.01015054886 0.021907728416 -2.7794 0.1134 0.2279 0.2275 0.2049 0.1313 0.184280201 HKDC1 hexokinase domain containing 1 0.00047133747 0.001398778354 -2.7811 0.6126 0.4349 0.4538 0.6820 0.2219 0.3181493911 PHOSPHO2 phosphatase, orphan 2 3.67382209E-06 1.69429776E-05 -2.7817 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970197135 PATL2 protein associated with topoisomerase II homolog 2 (yeast) 3.18666507E-06 1.48597031E-05 -2.7817 2.2823 2.1053 1.8642 1.2553 3.3502 1.73794863 NPAT nuclear protein, ataxia-telangiectasia locus 3.27935257E-14 3.94212699E-12 -2.7825 2.4296 1.8485 0.5004 2.6652 1.9094 0.9496219285 SAMD9L sterile alpha motif domain containing 9-like 0.00514933693 0.012075036492 -2.7844 3.2264 1.9852 1.6408 2.2623 1.6609 1.3266100129858 LOC100129858 uncharacterized LOC100129858 0.00032688646 0.001007909097 -2.7847 6.9085 0.1188 0.2367 1.9382 0.1167 0.05716133 RPL9 ribosomal protein L9 4.37818213E-12 1.37927834E-10 -2.7866 0.8237 1.4489 2.3232 0.8771 1.7281 1.492057326 PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 1.32760288E-06 6.74206777E-06 -2.7874 3.1047 1.5914 2.2540 2.1222 1.2267 1.5722728936 NBPF16 neuroblastoma breakpoint family, member 16 3.65419399E-09 3.58397384E-08 -2.7875 0.1507 0.1207 0.3128 0.2723 0.0840 0.2464100507062 PSMD6-AS2 PSMD6 antisense RNA 2 3.2390489E-05 0.000122205041 -2.7912 0.1844 0.1367 0.2083 0.3596 0.1270 0.13711488 CTBP2 C-terminal binding protein 2 3.56398309E-05 0.000133636567 -2.7917 0.3218 0.4422 0.3563 0.2755 0.2746 0.3007221002 RASGEF1A RasGEF domain family, member 1A 0.00042009498 0.001261458587 -2.7924 0.6688 1.1476 1.1586 0.4153 0.5200 0.65496925 TCF4 transcription factor 4 0.00228615485 0.005846413079 -2.7931 0.4711 0.6912 0.3943 0.4973 0.5975 0.319253822 FXYD7 FXYD domain containing ion transport regulator 7 0.00057281815 0.00167063578 -2.7936 0.3557 0.8423 0.8980 0.2715 0.6119 0.6719254295 PHYHD1 phytanoyl-CoA dioxygenase domain containing 1 0.00560110013 0.012984433088 -2.7939 0.7364 0.6678 0.4244 0.5180 0.8080 0.3578401647 GOLGA7B golgin A7 family, member B 0.00023835667 0.000755857872 -2.7948 2.2267 2.4816 1.9310 1.6828 2.1339 1.38836232 RPS27 ribosomal protein S27 2.10008515E-10 3.11720193E-09 -2.7955 2.0879 1.5513 1.8752 2.1456 2.0179 2.163379092 CARD14 caspase recruitment domain family, member 14 0.00060130019 0.001744238316 -2.7999 0.0772 0.0300 0.1658 0.1893 0.0598 0.143211039 SMA4 glucuronidase, beta pseudogene 7.09513518E-06 3.07865851E-05 -2.8003 0.1631 0.1960 0.2050 0.3768 0.1929 0.26179398 CD101 CD101 molecule 6.73484353E-05 0.000239834459 -2.8010 1.6361 0.7299 1.3788 1.0651 0.5833 0.7178154743 C7orf60 hypothetical protein FLJ31818 2.42205001E-10 3.5291625E-09 -2.8012 2.2657 2.5380 2.5578 1.8861 2.2177 2.6044395 ARHGAP6 Rho GTPase activating protein 6 0.00014060296 0.000468129978 -2.8026 0.2537 0.4808 0.3334 0.2802 0.2813 0.29039710 KIAA0355 KIAA0355 3.2048552E-11 6.59600581E-10 -2.8031 1.1565 1.6790 1.0765 1.1184 1.2831 1.059510283 CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 1.37001585E-09 1.53954057E-08 -2.8051 5.2794 1.5921 2.0239 3.6728 1.6797 0.8646730091 LINC00886 hypothetical protein LOC730091 0.00810651126 0.017989090818 -2.8069 2.3536 2.6232 2.8834 1.4899 1.5001 3.01553315 HSPB1 heat shock 27kDa protein 1 1.69085745E-08 1.36042921E-07 -2.8078 1.3207 1.7871 1.8680 0.9073 1.9776 1.880711167 FSTL1 follistatin-like 1 0.00452134303 0.010765439122 -2.8089 1.2740 1.0462 0.8971 1.3333 0.6103 0.794554947 LPCAT2 lysophosphatidylcholine acyltransferase 2 0.0008135429 0.002302161362 -2.8094 0.2375 0.9193 0.6200 0.2894 0.5104 0.49727077 TIMP2 TIMP metallopeptidase inhibitor 2 0.00091671266 0.002569439129 -2.8105 0.5434 0.8625 0.6157 0.3469 0.7123 0.5142100499177 THAP9-AS1 THAP9 antisense RNA 1 5.86765688E-08 4.1101188E-07 -2.8110 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970132864 CPEB2 cytoplasmic polyadenylation element binding protein 2 2.28994315E-09 2.37467885E-08 -2.8127 5.0903 4.4291 1.7433 7.0869 2.9301 3.4575201799 TMEM154 transmembrane protein 154 6.74424451E-09 6.09148965E-08 -2.8127 2.2877 2.4233 2.3224 1.9445 2.8136 1.93195922 RASA2 RAS p21 protein activator 2 8.45123761E-15 1.54421014E-12 -2.8131 0.8758 0.9498 1.1496 0.9130 0.9869 1.2152644591 PPIAL4G peptidylprolyl isomerase A (cyclophilin A)-like 4G 3.88926242E-06 1.7824079E-05 -2.8132 1.2899 0.9540 0.4685 1.2839 0.8246 0.429810150 MBNL2 muscleblind-like splicing regulator 2 2.23909809E-07 1.36239761E-06 -2.8133 0.8220 0.4494 0.5504 0.9713 0.3749 0.5092284390 ZNF763 zinc finger protein 763 0.00016754466 0.000547456379 -2.8141 1.1622 1.0609 0.9815 0.9604 0.9557 1.019351322 WAC WW domain containing adaptor with coiled-coil 1.09934255E-14 1.79349884E-12 -2.8142 4.0892 4.0966 1.5844 5.5440 7.9438 3.35861387 CREBBP CREB binding protein 2.73038417E-14 3.4170945E-12 -2.8187 3.3009 3.3017 1.7081 3.1598 3.6563 2.0510402573 C7orf61 hypothetical LOC402573 0.00375174505 0.009113000612 -2.8204 0.0419 0.0527 0.1867 0.0800 0.0236 0.154110468 FST follistatin 0.02617125904 0.049755618066 -2.8209 2.5921 4.0661 2.5131 1.7810 2.7760 2.3041100126791 EGOT eosinophil granule ontogeny transcript (non-protein coding) 0.00095027576 0.002654148389 -2.8217 0.2435 0.2216 1.4051 0.3349 0.1426 0.6632492311 IGIP IgA-inducing protein 1.36488967E-06 6.9160466E-06 -2.8223 0.2294 0.3511 0.2042 0.2822 0.1190 0.1424345930 ECT2L epithelial cell transforming sequence 2 oncogene-like 0.00358823913 0.008751242051 -2.8233 0.1661 0.2583 0.3158 0.3324 0.1255 0.3463284346 ZNF575 zinc finger protein 575 1.47083228E-06 7.39544509E-06 -2.8258 2.1202 2.2331 2.1658 1.4482 2.0944 2.21898972 MGAM maltase-glucoamylase (alpha-glucosidase) 0.02514458628 0.048078890798 -2.8262 0.0460 0.1228 0.0357 0.2351 0.0627 0.27863640 INSL3 insulin-like 3 (Leydig cell) 1.71657664E-06 8.51623361E-06 -2.8293 0.0388 0.0255 0.1577 0.1554 0.0625 0.1833142686 ASB14 ankyrin repeat and SOCS box-containing 14 6.45808935E-06 2.82437072E-05 -2.8296 0.0362 0.0205 0.1235 0.1299 0.1043 0.162065109 UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 1.35427317E-09 1.52560292E-08 -2.8303 1.9626 3.0985 2.1268 1.9794 2.1532 2.0463

55008 HERC6 0.0026447978 0.006670220202 -2.8335 1.1333 1.0448 0.9886 1.2484 0.8873 0.81221124 CHN2 chimerin 2 0.00225003994 0.005761313036 -2.8342 0.2787 0.1407 0.1858 0.2371 0.1158 0.19821386 ATF2 activating transcription factor 2 1.95273546E-12 7.28171067E-11 -2.8356 4.4543 1.1084 1.2268 1.7675 2.2901 1.354655911 APOBR apolipoprotein B48 receptor 0.00010686774 0.0003648519 -2.8365 1.8379 1.7459 2.4540 1.0292 0.9604 1.4063100506713 LOC100506713 uncharacterized LOC100506713 2.5317654E-06 1.20752852E-05 -2.8369 4.0954 7.1232 0.4890 9.1025 8.7999 0.473410644 IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.00109272331 0.003011173435 -2.8383 0.7774 1.2040 1.0301 0.6712 1.1345 0.9368284565 NBPF15 neuroblastoma breakpoint family, member 15 2.97899912E-09 3.00730784E-08 -2.8398 0.6258 0.4236 0.5587 0.4937 0.2910 0.3453100507217 LOC100507217 uncharacterized LOC100507217 6.41249168E-10 8.04180151E-09 -2.8399 3.2341 1.7657 2.3901 2.8627 2.4395 2.7160162993 ZNF846 zinc finger protein 846 2.93284619E-06 1.37867161E-05 -2.8399 3.1194 2.0810 2.0097 3.4847 2.8763 2.9269

5742 PTGS1 0.0087768769 0.019277688981 -2.8442 0.2269 0.3850 0.6793 0.3418 0.1848 0.5038

11046 SLC35D2 6.31505478E-07 3.44033038E-06 -2.8451 1.7893 2.5340 0.9188 0.9198 2.1714 0.6174221476 PI16 peptidase inhibitor 16 0.01692300904 0.034126169437 -2.8473 1.2889 0.6630 0.9301 0.7805 0.5066 0.4113100505975 ENO1-AS1 ENO1 antisense RNA 1 0.01413502735 0.029210045209 -2.8491 2.1479 1.9633 0.9244 2.3377 11.2637 2.499510443 N4BP2L2 NEDD4 binding protein 2-like 2 1.37509378E-11 3.36805811E-10 -2.8494 0.9555 0.7854 0.6701 1.3161 1.1443 0.89424778 NFE2 nuclear factor, erythroid 2 0.01012213145 0.021859305731 -2.8504 0.2829 0.4286 0.5178 0.1882 0.5091 0.520057471 ERMN ermin, ERM-like protein 0.00024976517 0.000789569051 -2.8506 0.8624 0.6055 0.8316 0.7284 0.5405 0.4489387066 SNHG5 small nucleolar RNA host gene 5 (non-protein coding) 1.40853926E-08 1.16245842E-07 -2.8527 1.5118 2.5556 2.1184 0.6914 1.7789 2.73463912 LAMB1 laminin, beta 1 0.00132528686 0.003585377786 -2.8530 1.0982 1.2824 1.4238 0.9840 0.5401 0.864625927 CNRIP1 cannabinoid receptor interacting protein 1 0.01149190068 0.02439358844 -2.8547 0.7909 1.2313 0.7049 0.5669 0.4276 0.518965986 ZBTB10 zinc finger and BTB domain containing 10 4.46208221E-09 4.27536267E-08 -2.8556 1.9103 2.4794 1.1370 1.6771 3.1137 2.439423236 PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 6.75130561E-05 0.000240373843 -2.8578 0.7228 0.8922 0.5241 0.6058 0.6158 0.551955959 SULF2 sulfatase 2 0.00379284712 0.009197459089 -2.8583 0.3738 0.3879 0.3315 0.3115 0.2406 0.367254760 PCSK4 proprotein convertase subtilisin/kexin type 4 0.00011759592 0.000398130925 -2.8584 0.3871 0.9646 0.6649 0.3163 0.5948 0.6893283651 HMGN2P46 chromosome 15 open reading frame 21 0.01714244288 0.034507735628 -2.8594 0.0911 0.0901 0.1266 0.4150 0.0106 0.08929737 GPRASP1 G protein-coupled receptor associated sorting protein 1 7.74235492E-06 3.33415765E-05 -2.8597 1.3822 1.8862 1.7502 2.0063 2.3450 2.027811236 RNF139 ring finger protein 139 9.4096296E-13 4.11322373E-11 -2.8632 2.7744 2.6829 1.3423 3.1766 4.9016 2.692423112 TNRC6B trinucleotide repeat containing 6B 2.8438217E-12 9.69446082E-11 -2.8634 1.9761 1.9040 1.6236 1.7170 1.8264 1.556355904 KMT2E lysine (K)-specific methyltransferase 2E 5.61256996E-14 5.42607822E-12 -2.8657 1.6150 4.0567 0.6546 1.8106 5.3463 1.14149452 ITM2A integral membrane protein 2A 1.42587943E-10 2.22111414E-09 -2.8676 1.9780 2.6621 1.8230 1.9196 3.7269 2.321810737 RFPL3S RFPL3 antisense 0.00258889587 0.006541875993 -2.8683 0.0402 0.0409 0.0987 0.1188 0.0076 0.1018

metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)

WAS protein homolog associated with actin, golgi membranes and microtubules

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2

118490 MSS51 MSS51 mitochondrial translational activator 1.47764875E-06 7.42359031E-06 -2.8704 0.4566 0.3770 0.3862 0.2820 0.1434 0.291526960 NBEA neurobeachin 1.93517811E-05 7.64200874E-05 -2.8760 0.7696 0.6432 0.9407 0.6483 0.5962 0.7799

79800 CARF 1.49775007E-07 9.51891798E-07 -2.8774 3.7973 9.2592 5.0135 1.5581 8.6795 2.8617643180 CCT6P3 chaperonin containing TCP1, subunit 6A pseudogene 5.51253866E-07 3.0439742E-06 -2.8789 2.9822 1.9342 1.3506 1.7502 1.6630 1.705184162 KIAA1109 KIAA1109 6.99032836E-13 3.34364607E-11 -2.8802 0.1476 0.1283 0.1397 0.2855 0.0973 0.14208555 CDC14B cell division cycle 14B 0.00020852862 0.000668227821 -2.8807 1.5681 2.0418 1.3961 1.3055 0.9510 1.353426119 LDLRAP1 low density lipoprotein receptor adaptor protein 1 1.99863202E-07 1.23416709E-06 -2.8816 1.1341 2.0628 1.9372 1.1767 1.6781 1.32947620 ZNF69 zinc finger protein 69 0.00026608363 0.000836812396 -2.8818 1.8071 1.7469 1.9085 1.9047 1.6536 1.867126289 AK5 adenylate kinase 5 3.37567759E-05 0.000126940484 -2.8823 1.8738 2.4994 2.0331 1.4476 2.4185 1.5736155435 RBM33 RNA binding motif protein 33 4.00433545E-14 4.48878634E-12 -2.8832 0.9002 1.8570 0.8069 1.3194 2.9627 1.021280350 LPAL2 lipoprotein, Lp(a)-like 2, pseudogene 0.00222990946 0.005716176432 -2.8845 0.0669 0.0675 0.1865 0.3295 0.1176 0.1761100129961 LOC100129961 uncharacterized LOC100129961 0.00028637592 0.000893250397 -2.8919 1.4141 1.8084 3.5068 0.7732 1.3557 2.7046100507463 TAPSAR1 TAP1 and PSMB8 antisense RNA 1 2.69584247E-09 2.7503313E-08 -2.8935 0.3321 0.3321 0.3321 0.3970 0.3970 0.39703213 HOXB3 homeobox B3 8.09851235E-06 3.4695432E-05 -2.8956 0.4597 1.0182 0.5737 0.9390 0.9145 0.487926157 GIMAP2 GTPase, IMAP family member 2 3.33938131E-08 2.48340152E-07 -2.8960 3.1125 3.3288 2.4405 3.0468 3.1956 2.1573339201 ASB16-AS1 chromosome 17 open reading frame 65 6.08767009E-06 2.67389201E-05 -2.8966 7.1441 2.2979 1.0352 2.9219 3.0843 0.76011396 CRIP1 cysteine-rich protein 1 (intestinal) 7.36393655E-08 5.0489249E-07 -2.8968 1.0896 1.1227 2.0673 0.6774 0.8351 2.4400126259 TMIGD2 transmembrane and immunoglobulin domain containing 2 1.41415843E-07 9.03479118E-07 -2.8971 1.8087 1.9024 2.4956 1.1423 0.8024 2.12572946 GSTM2 glutathione S-transferase mu 2 (muscle) 1.53970294E-09 1.69887996E-08 -2.9014 0.9362 1.5084 0.9678 0.6336 1.1662 0.6401401577 CD99P1 hypothetical protein LOC401577 4.79345356E-13 2.59130129E-11 -2.9026 2.1797 2.4546 2.4684 1.9782 3.4002 3.4410100130519 TMEM221 transmembrane protein 221 0.01904417246 0.03782338252 -2.9030 0.4841 0.7354 1.3060 0.2194 0.8464 0.520291351 DDX60L hypothetical protein FLJ31033 0.00692615847 0.015647378551 -2.9039 0.9313 0.7079 1.0527 1.0887 0.4851 0.9114

130271 PLEKHH2 3.62345754E-05 0.00013575521 -2.9041 2.3914 1.7818 2.3060 1.6738 1.1059 2.097080314 EPC1 enhancer of polycomb homolog 1 (Drosophila) 1.77899467E-14 2.55951107E-12 -2.9043 2.3147 3.2176 1.6721 2.5074 4.9228 2.7475240 ALOX5 arachidonate 5-lipoxygenase 0.02414201531 0.046492717502 -2.9064 1.0821 3.5367 1.4076 0.7215 2.0381 0.824722902 RUFY3 RUN and FYVE domain containing 3 7.47536218E-08 5.11764023E-07 -2.9102 1.9733 1.4578 1.4883 1.4070 1.3455 1.2316100507117 ASAP1-IT2 ASAP1 intronic transcript 2 (non-protein coding) 0.01622554238 0.032912201421 -2.9117 0.0623 0.1310 0.3395 0.1813 0.3975 0.21598313 AXIN2 axin 2 4.53407519E-07 2.55620555E-06 -2.9117 1.1175 0.8116 0.9138 0.8788 0.7853 0.8836149628 PYHIN1 pyrin and HIN domain family, member 1 4.13931212E-06 1.88350413E-05 -2.9127 2.1392 1.3687 1.1120 1.6681 0.5968 0.84172186 BPTF bromodomain PHD finger transcription factor 3.71376394E-17 8.75611785E-14 -2.9130 0.6978 0.8031 0.5779 0.7400 1.1505 0.98906154 RPL26 ribosomal protein L26 3.35882549E-13 1.99261232E-11 -2.9196 2.0116 2.6329 2.1815 2.3139 5.0921 3.6160221481 ARMC12 chromosome 6 open reading frame 81 0.00951736868 0.02070747326 -2.9200 0.0315 0.0880 0.1400 0.2438 0.0419 0.05858842 PROM1 prominin 1 0.00480301902 0.011362087452 -2.9215 0.7261 1.0014 0.5487 0.4862 1.0469 0.38638642 DCHS1 dachsous cadherin-related 1 0.00010091289 0.0003466592 -2.9221 0.9811 0.8499 0.9804 1.1885 0.3514 0.6660729830 FAM160A1 family with sequence similarity 160, member A1 0.00784339288 0.01746246797 -2.9231 2.5766 2.7403 2.0136 1.9170 0.9821 1.558751266 CLEC1B C-type lectin domain family 1, member B 0.00458047372 0.010889203198 -2.9234 0.0159 0.0362 0.1043 0.1181 0.0122 0.1263

7881 KCNAB1 6.23994458E-07 3.40855807E-06 -2.9261 0.1593 0.1338 0.1704 0.2912 0.0794 0.17086206 RPS12 ribosomal protein S12 1.28065394E-11 3.16217687E-10 -2.9268 3.4551 5.1558 1.9460 3.9139 5.3439 4.248557677 ZFP14 ZFP14 zinc finger protein 2.76004099E-06 1.3055001E-05 -2.9285 0.7496 0.8722 1.2434 0.8325 0.6518 1.387529761 USP25 ubiquitin specific peptidase 25 3.4362572E-13 2.02062076E-11 -2.9321 2.4550 3.2788 1.4479 2.9852 3.1943 2.03965125 PCSK5 proprotein convertase subtilisin/kexin type 5 2.3487641E-06 1.12908755E-05 -2.9322 1.3640 1.3035 1.4173 1.7489 1.5942 1.6740645811 CCDC154 similar to ciliary rootlet coiled-coil, rootletin 0.01257243302 0.026380741397 -2.9324 0.0392 0.0477 0.0752 0.1647 0.0309 0.10981519 CTSO cathepsin O 2.09436556E-05 8.21912531E-05 -2.9334 1.4495 1.6835 1.3939 1.5956 1.8922 1.2835

339005 WHAMMP3 7.13164165E-05 0.000252733429 -2.9336 1.4126 1.0071 0.9838 1.3355 0.9552 1.02146668 SP2 Sp2 transcription factor 2.16546096E-13 1.45468025E-11 -2.9375 2.3036 2.7066 1.5872 2.3426 3.5107 2.111955024 BANK1 B-cell scaffold protein with ankyrin repeats 1 0.02297847046 0.044476971629 -2.9384 0.6359 0.7969 0.6636 0.6434 0.4240 0.3530963 CD53 CD53 molecule 2.77847293E-10 3.98494957E-09 -2.9398 1.6481 1.4409 1.4265 1.7265 1.6033 1.56647125 TNNC2 troponin C type 2 (fast) 0.00019634293 0.000632060954 -2.9403 0.1331 0.1874 0.1541 0.1197 0.9362 0.178722864 R3HDM2 R3H domain containing 2 4.85850086E-15 1.09598182E-12 -2.9405 0.4814 0.7843 0.6397 0.5299 0.5772 0.6601129530 LYG1 lysozyme G-like 1 0.00021376127 0.00068319853 -2.9408 0.0482 0.0163 0.1571 0.2976 0.0379 0.17629762 LZTS3 leucine zipper, putative tumor suppressor family member 3 7.46084408E-06 3.22356451E-05 -2.9411 1.2062 1.3304 1.1378 1.1426 1.3767 1.0687256380 SCML4 sex comb on midleg-like 4 (Drosophila) 0.00022265137 0.000708884105 -2.9419 1.8100 1.8332 1.3853 1.7097 1.0851 0.99942982 GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00515104468 0.012077491141 -2.9435 0.8464 1.7112 1.1831 0.5662 0.9763 0.962226586 CKAP2 cytoskeleton associated protein 2 3.45157676E-10 4.76338448E-09 -2.9464 1.9323 2.8485 2.1842 1.8798 3.9956 2.50975729 PTGDR prostaglandin D2 receptor (DP) 0.00321915617 0.007944411347 -2.9468 0.8426 1.4086 0.9419 0.9961 0.5286 0.65421191 CLU clusterin 0.00330065342 0.008120309581 -2.9486 0.5774 0.6151 0.7893 0.4199 0.3670 0.667584265 POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like 8.4273171E-12 2.27114953E-10 -2.9505 3.0850 1.2524 0.3189 1.9522 0.5442 0.230454407 SLC38A2 solute carrier family 38, member 2 5.71898843E-09 5.28680076E-08 -2.9548 1.6441 1.5979 1.5645 1.6350 1.6537 1.917411092 C9orf9 chromosome 9 open reading frame 9 3.08552226E-05 0.00011696818 -2.9552 0.4429 1.9767 0.8234 0.1781 3.2493 0.99381400 CRMP1 collapsin response mediator protein 1 0.02014354548 0.03970473172 -2.9560 0.2348 0.1314 0.2108 0.2050 0.0528 0.180555056 FLJ10038 uncharacterized protein FLJ10038 1.41698367E-08 1.16731856E-07 -2.9567 0.3321 0.3321 0.3321 0.3970 0.3970 0.397051710 ZNF44 zinc finger protein 44 2.51910468E-13 1.61813867E-11 -2.9580 1.2675 2.6971 1.6698 1.1181 3.6624 2.120984077 C3orf20 chromosome 3 open reading frame 20 0.01236445666 0.02599808424 -2.9582 0.0633 0.0301 0.1489 0.1299 0.1212 0.116455930 MYO5C myosin VC 5.15840195E-06 2.30676261E-05 -2.9602 0.6635 0.7480 1.0195 0.3183 0.3433 0.8390120224 TMEM45B transmembrane protein 45B 7.99408579E-06 3.43285395E-05 -2.9622 0.4875 0.7711 0.7012 0.5653 0.5413 0.51182549 GAB1 GRB2-associated binding protein 1 0.00644257884 0.014694644945 -2.9639 0.8725 0.8863 0.8842 0.8136 0.5580 1.103055790 CSGALNACT1 chondroitin beta1,4 N-acetylgalactosaminyltransferase 2.27008489E-06 1.09385525E-05 -2.9669 1.3398 1.1657 0.9965 1.2550 0.7876 0.7813100130000 LOC100130000 phosphodiesterase 4D interacting protein pseudogene 3.93030503E-07 2.25335844E-06 -2.9675 1.7965 1.5415 1.5683 1.5970 1.3611 1.59788556 CDC14A cell division cycle 14A 1.33853187E-09 1.51159792E-08 -2.9678 0.9845 0.7940 0.7646 1.4310 1.3539 1.7969284391 ZNF844 hypothetical protein FLJ14959 2.52848932E-06 1.20628086E-05 -2.9719 1.4809 1.7549 1.2682 1.4921 1.5246 1.58456322 SCML1 sex comb on midleg-like 1 (Drosophila) 3.04545534E-06 1.42646911E-05 -2.9722 1.6337 3.3804 1.8528 3.0417 3.6362 2.8338287 ANK2 ankyrin 2, neuronal 0.01358442572 0.028228662213 -2.9734 0.1530 0.0925 0.3932 0.2778 0.1501 0.369823037 PDZD2 PDZ domain containing 2 1.04681961E-05 4.37599813E-05 -2.9761 0.8305 0.7806 0.6724 0.8734 0.7885 0.532151019 CCDC53 coiled-coil domain containing 53 2.97809992E-10 4.21175246E-09 -2.9775 2.2287 2.2291 1.3336 2.0455 2.2731 1.72011010 CDH12 cadherin 12, type 2 (N-cadherin 2) 0.0020859994 0.005389618372 -2.9803 0.6770 0.4460 0.3719 0.3723 0.2300 0.2547728323 LOC728323 uncharacterized LOC728323 5.89572403E-07 3.23600689E-06 -2.9832 0.7766 0.5756 0.9672 0.7769 0.7756 1.1138353355 ZNF233 zinc finger protein 233 0.02421871944 0.046620779776 -2.9854 0.5294 0.7808 1.0614 0.4016 0.4474 0.9983123688 HYKK hydroxylysine kinase 7.28726186E-07 3.91971883E-06 -2.9857 1.6149 1.8561 2.0130 1.3228 1.4475 1.869557690 TNRC6C trinucleotide repeat containing 6C 1.1240918E-13 8.59389343E-12 -2.9869 0.2041 0.5729 0.4324 0.2691 0.3967 0.2023

4300 MLLT3 1.37398843E-12 5.55431782E-11 -2.9889 2.2899 2.3266 1.5274 2.8326 3.7341 3.0158288 ANK3 ankyrin 3, node of Ranvier (ankyrin G) 8.59134794E-08 5.79908052E-07 -2.9916 0.5761 0.7832 0.6653 0.5851 0.6693 0.6133

5176 SERPINF1 0.00014113958 0.000469831008 -2.9918 0.1769 0.3045 0.3166 0.2329 0.1781 0.130592 ACVR2A activin A receptor, type IIA 5.59580297E-07 3.08319571E-06 -2.9919 2.8981 3.0336 2.1330 2.5744 2.8598 2.0440161247 FITM1 fat storage-inducing transmembrane protein 1 3.45914874E-05 0.000129999107 -2.9961 0.4655 0.3493 0.7578 0.5378 0.1383 0.4675641518 LEF1-AS1 LEF1 antisense RNA 1 1.7323064E-05 6.91408966E-05 -2.9999 1.7615 2.1896 1.5151 1.5397 4.2416 2.4902284443 ZNF493 zinc finger protein 493 5.80920642E-09 5.34739646E-08 -2.9999 1.8837 2.1316 1.4820 2.2588 2.7999 2.209064577 ALDH8A1 aldehyde dehydrogenase 8 family, member A1 0.0001703594 0.000555957663 -3.0002 0.1630 0.0672 0.1268 0.1516 0.0826 0.0667115548 FCHO2 FCH domain only 2 0.00022728216 0.000722872 -3.0054 0.4375 0.5295 0.5594 0.4399 0.5290 0.72607716 VEZF1 vascular endothelial zinc finger 1 2.96001785E-15 7.51186751E-13 -3.0070 1.4881 1.3482 1.1306 1.2691 1.3737 1.79368507 ENC1 ectodermal-neural cortex 1 (with BTB domain) 8.00553918E-06 3.43552298E-05 -3.0073 2.1662 2.4379 2.8359 1.4906 1.3665 1.7475145200 LINC00239 long intergenic non-protein coding RNA 239 4.70964212E-05 0.000172661679 -3.0076 0.5001 0.8150 1.4774 0.3451 0.2733 0.9574

6594 SMARCA1 0.00466694953 0.011071734844 -3.0078 1.2898 1.0686 0.8487 0.9790 0.5276 0.7852

6505 SLC1A1 0.02620148811 0.049800268295 -3.0084 1.0410 0.8774 1.6035 0.6859 0.7836 1.00722857 GPR34 G protein-coupled receptor 34 0.01766018824 0.035448419141 -3.0087 1.0269 0.5684 0.7168 0.8783 0.1469 0.1853313 AOAH acyloxyacyl hydrolase (neutrophil) 0.0004076878 0.001229671799 -3.0094 2.6358 2.4346 1.7836 1.7790 0.7869 0.89148349 HIST2H2BE histone cluster 2, H2be 4.55367928E-07 2.566466E-06 -3.0099 3.0144 6.2096 2.1460 2.4566 3.7564 2.908984217 ZMYND12 zinc finger, MYND-type containing 12 0.00482210021 0.011399846682 -3.0099 0.3509 0.8546 0.5478 1.1892 0.7945 0.3615285965 EPHA1-AS1 hypothetical protein LOC285965 0.00040594296 0.001225407207 -3.0101 2.5832 1.0913 1.4860 2.1640 0.3641 0.7230162632 USP32P1 ubiquitin specific peptidase 32 pseudogene 1 8.75780186E-06 3.72578709E-05 -3.0102 0.0907 0.0465 0.1326 0.1835 0.0368 0.185357698 KIAA1598 KIAA1598 0.00368621524 0.008966257307 -3.0112 0.3301 0.4049 0.4855 0.5490 0.3619 0.53953580 CXCR2P1 chemokine (C-X-C motif) receptor 2 pseudogene 1 0.00535806494 0.012492351999 -3.0125 0.0899 0.0434 0.1739 0.6496 0.0144 0.31863337 DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.31806209E-09 1.49402175E-08 -3.0125 0.8404 3.3830 1.1917 0.9984 3.5970 1.744310643 IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00097850407 0.002725491827 -3.0156 1.4298 1.2543 2.1189 1.1946 1.1276 1.20295925 RB1 retinoblastoma 1 3.35043172E-12 1.11307434E-10 -3.0156 3.3670 1.7522 0.2335 1.6562 1.3872 0.47289550 ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 3.87230782E-12 1.2522975E-10 -3.0167 1.9231 2.5591 2.5677 2.0708 2.9958 3.0821

645784 ANKRD36BP2 Similar to protein immuno-reactive with anti-PTH polyclonal antibodies 0.00033499475 0.001029781971 -3.0168 1.3942 2.2847 1.3641 1.2092 1.4948 1.37595342 PLGLB2 plasminogen-like B2 5.07954897E-05 0.000184998044 -3.0171 0.0496 0.0817 0.1690 0.1160 0.2503 0.209179600 TCTN1 tectonic 1 2.37306612E-07 1.43625916E-06 -3.0222 1.0927 1.8345 1.2649 0.8158 1.7578 1.30237538 ZFP36 ZFP36 ring finger protein 1.23764557E-07 8.00504776E-07 -3.0231 1.7123 2.6750 1.8043 1.9420 3.5106 2.611779841 AGBL2 ATP/GTP binding protein-like 2 0.00102028079 0.002828383556 -3.0236 0.8321 0.7413 0.7482 0.8464 0.6023 0.5715345778 MTX3 metaxin 3 4.75578059E-10 6.23816388E-09 -3.0249 2.1038 1.6493 2.6143 1.7111 1.2715 2.60125167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00299504987 0.007455797164 -3.0249 0.8798 0.5729 0.7403 0.5152 0.3816 0.6677253461 ZBTB38 zinc finger and BTB domain containing 38 1.1841627E-07 7.70274862E-07 -3.0257 0.6619 0.8118 0.7731 0.6318 0.5091 0.6717900 CCNG1 cyclin G1 2.99509388E-11 6.24017736E-10 -3.0283 2.0543 1.9022 1.7939 1.7660 1.8528 2.060151206 GP6 glycoprotein VI (platelet) 3.73974488E-05 0.000139882535 -3.0313 0.1254 0.1264 0.3110 0.3187 0.1973 0.3986642236 LOC642236 FSHD region gene 1 pseudogene 4.75747537E-07 2.67134799E-06 -3.0320 0.6157 0.9421 0.4125 0.7221 0.9296 0.4488286437 LOC286437 hypothetical protein LOC286437 5.64968817E-05 0.000204014036 -3.0359 0.5236 0.7957 0.7217 0.4844 0.4206 0.695680209 PROSER1 proline and serine rich 1 1.36585065E-11 3.34990914E-10 -3.0416 6.8130 4.1480 2.2180 3.6349 6.4483 2.5526387882 C12orf75 overexpressed in colon carcinoma-1 2.70028632E-10 3.89420928E-09 -3.0423 1.6417 1.5983 1.7742 1.0715 1.6206 1.81257644 ZNF91 zinc finger protein 91 1.40427434E-13 1.02226696E-11 -3.0426 2.1771 2.0120 1.1958 2.4146 4.4085 1.93338654 PDE5A phosphodiesterase 5A, cGMP-specific 0.00010513635 0.000359814846 -3.0431 2.0599 2.6231 1.7693 1.4083 1.9639 1.4359304 ANXA2P2 annexin A2 pseudogene 2 0.00028329356 0.000884844444 -3.0432 0.2411 0.1448 0.4098 0.4971 0.0314 0.3064199786 FAM129C family with sequence similarity 129, member C 0.01137202666 0.024158780502 -3.0437 0.6518 1.1556 1.1099 0.4777 0.5642 0.8128100506343 LOC100506343 uncharacterized LOC100506343 0.01749975586 0.035161154504 -3.0453 3.0184 3.2988 2.7475 2.2232 1.9559 2.14712047 EPHB1 EPH receptor B1 0.01735091479 0.034888952897 -3.0480 0.3349 0.4524 0.4721 0.3021 0.2357 0.3254100507404 TMLHE-AS1 TMLHE antisense RNA 1 0.00643095557 0.014671796745 -3.0482 0.9768 1.2786 1.1875 0.7042 0.9302 0.53707091 TLE4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 2.26073328E-12 8.05226483E-11 -3.0484 2.2304 2.3005 1.1320 2.0307 1.9344 1.6045654816 NCF1B neutrophil cytosolic factor 1B pseudogene 0.00063139137 0.001824285759 -3.0490 0.3219 0.2816 0.5435 0.2749 0.2094 0.282385478 CCDC65 coiled-coil domain containing 65 3.32164711E-06 1.54514094E-05 -3.0498 0.9047 1.6255 0.7315 0.7637 0.7942 0.595451306 FAM13B family with sequence similarity 13, member B 5.05524779E-11 9.50303371E-10 -3.0528 1.4129 1.7000 2.1509 2.1161 3.2843 3.511111231 SEC63 SEC63 homolog (S. cerevisiae) 1.37318033E-13 1.00766068E-11 -3.0540 0.9695 0.8186 0.8871 1.1889 1.1055 1.4761374618 TEX9 testis expressed 9 0.00691639465 0.015632899937 -3.0568 1.3232 1.7997 1.3699 0.8738 2.0701 1.013681027 TUBB1 tubulin, beta 1 class VI 0.00151778784 0.004052165318 -3.0642 0.0967 0.2305 0.2975 0.3918 0.0794 0.16788601 RGS20 regulator of G-protein signaling 20 0.01424017294 0.029394084952 -3.0649 0.5664 1.0950 1.1055 0.6118 0.9019 0.91598560 DEGS1 delta(4)-desaturase, sphingolipid 1 1.13342673E-14 1.83274099E-12 -3.0658 1.5353 2.1044 2.1439 1.7403 2.7016 3.1402

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8

pleckstrin homology domain containing, family H (with MyTH4 domain) member 2

potassium voltage-gated channel, shaker-related subfamily, beta member 1

WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

83716 CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00851176272 0.0187598595 -3.0690 0.9975 1.5259 0.8378 0.4901 0.6127 0.576923097 CDK19 cyclin-dependent kinase 19 1.29010376E-10 2.04624791E-09 -3.0697 1.2766 0.7142 1.2517 1.1802 0.9665 1.2619645212 EIF3J-AS1 EIF3J antisense RNA 1 (head to head) 2.34088245E-07 1.41771972E-06 -3.0712 3.2510 1.9311 2.7179 1.6621 0.9993 2.267023209 MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.00349613023 0.008554002628 -3.0728 1.0064 0.8673 0.8571 0.7645 0.3499 0.547225946 ZNF385A zinc finger protein 385A 0.00129638295 0.003514988751 -3.0730 0.6985 1.1546 0.8861 0.4437 1.2497 0.539056891 LGALS14 lectin, galactoside-binding, soluble, 14 0.00041639544 0.001252518174 -3.0731 0.2515 0.4281 1.0311 0.1529 0.4623 0.5517100505716 LOC100505716 uncharacterized LOC100505716 0.00039456915 0.001193834645 -3.0751 0.1237 0.0695 0.2123 0.2493 0.0456 0.230910125 RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 2.77483964E-10 3.98494957E-09 -3.0769 0.9213 1.2123 1.1327 1.0069 1.5382 1.200110580 SORBS1 sorbin and SH3 domain containing 1 0.00011404843 0.000386981045 -3.0772 0.3318 0.3244 0.4389 0.3899 0.1927 0.4377100129250 TOPORS-AS1 TOPORS antisense RNA 1 1.62522657E-07 1.02506524E-06 -3.0791 3.2836 2.7451 1.8452 2.7216 2.8107 2.7901146225 CMTM2 CKLF-like MARVEL transmembrane domain containing 2 0.00169331575 0.004464684773 -3.0794 1.0955 0.5705 0.7467 0.6854 0.7926 0.661384898 PLXDC2 plexin domain containing 2 0.00836089483 0.0184661272 -3.0802 0.5029 0.1516 0.4540 0.5422 0.1420 0.392623043 TNIK TRAF2 and NCK interacting kinase 4.26939548E-12 1.3519999E-10 -3.0811 0.6522 0.6766 0.5580 0.9854 1.4269 1.2011100506710 LOC100506710 endogenous Bornavirus-like nucleoprotein 2 pseudogene 7.8162751E-13 3.60653986E-11 -3.0832 1.7418 2.0143 1.7470 1.7624 3.1519 2.6406170961 ANKRD24 ankyrin repeat domain 24 0.00117455773 0.003216654493 -3.0840 0.2544 0.3029 0.3563 0.3205 0.2199 0.3372345895 RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 0.00300462046 0.007476566129 -3.0845 2.2430 1.2884 2.3485 1.6838 1.1038 1.3102100130958 SYCE1L synaptonemal complex central element protein 1-like 1.85713287E-05 7.36981197E-05 -3.0857 0.6488 0.9266 0.8330 0.9535 1.0847 0.86971027 CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.97865297E-09 2.09953235E-08 -3.0859 1.7843 2.4594 2.4184 2.2791 3.8231 4.6519257144 GCSAM germinal center expressed transcript 2 3.36917279E-09 3.34220928E-08 -3.0877 2.9085 1.8994 1.8409 2.6132 1.8417 1.0117387914 SHISA2 shisa family member 2 0.02441881995 0.046931805847 -3.0892 1.1204 2.5383 1.6937 0.8835 1.9859 1.4992440295 GOLGA6L9 golgin A6 family-like 9 2.55653686E-07 1.53397649E-06 -3.0906 0.1728 0.2847 0.2839 0.3613 0.1151 0.2589222161 DKFZP586I1420 hypothetical protein DKFZp586I1420 4.03589931E-08 2.95566942E-07 -3.0916 0.1191 0.0501 0.0586 0.1016 0.1046 0.097479839 CCDC102B coiled-coil domain containing 102B 2.24061593E-05 8.73847105E-05 -3.0925 0.2748 0.2455 0.6454 0.3897 0.2326 0.20651193 CLIC2 chloride intracellular channel 2 0.00015563441 0.000512203159 -3.0978 0.1312 0.3942 0.7447 0.3318 0.1617 0.4633340542 BEX5 NGFRAP1-like 1 5.10012518E-09 4.78877119E-08 -3.0984 2.1634 2.2364 1.2759 2.0575 1.9458 1.50511060 CENPC centromere protein C 7.09630381E-14 6.32505674E-12 -3.0986 0.9159 1.1253 0.5273 0.9092 2.1960 0.8060162962 ZNF836 zinc finger protein 836 1.36973599E-08 1.13248036E-07 -3.1013 2.4873 1.7023 2.1734 2.1039 2.1136 2.30971441 CSF3R colony stimulating factor 3 receptor (granulocyte) 0.01503459672 0.030828431294 -3.1022 0.8623 0.8965 0.7284 0.5864 0.6496 0.55918328 GFI1B growth factor independent 1B transcription repressor 0.00750740684 0.016798351421 -3.1033 0.3782 0.6506 0.2953 0.2934 0.1452 0.2254

150159 SLC9B1 4.25970839E-05 0.000157398163 -3.1050 2.4010 2.0506 2.0681 1.9534 1.8589 1.509023522 KAT6B K(lysine) acetyltransferase 6B 2.15732174E-16 1.71385143E-13 -3.1054 1.2187 1.5684 1.6313 1.9223 2.9192 3.2907100131187 TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 1.29191146E-10 2.04733792E-09 -3.1056 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970375057 C1orf95 chromosome 1 open reading frame 95 0.00440515391 0.010516197065 -3.1057 1.3600 2.0782 1.9938 0.7450 1.3388 1.157155363 HEMGN hemogen 1.02095173E-06 5.30720627E-06 -3.1062 0.8600 1.1075 0.5884 0.5502 0.3891 0.3510152816 C4orf26 chromosome 4 open reading frame 26 0.01586648803 0.032266252055 -3.1065 0.0795 0.0377 0.2683 0.2002 0.2444 0.263879815 NIPAL2 NIPA-like domain containing 2 0.00990434457 0.021449826245 -3.1075 0.6525 0.4103 0.5266 0.4475 0.3969 0.392279686 LINC00341 long intergenic non-protein coding RNA 341 1.90281669E-09 2.03799921E-08 -3.1081 0.0347 0.0136 0.1844 0.1177 0.0106 0.1355158358 KIAA2026 KIAA2026 1.84086189E-14 2.62783035E-12 -3.1088 1.6207 0.4251 0.8151 1.6445 0.6977 0.43465412 UBL3 ubiquitin-like 3 7.22815841E-09 6.42690562E-08 -3.1100 0.6107 1.3210 1.8691 0.7902 2.1220 2.3138339883 C3orf35 chromosome 3 open reading frame 35 1.08380526E-05 4.51614359E-05 -3.1136 0.0797 0.0914 0.1863 0.3412 0.0410 0.25444058 LTK leukocyte receptor tyrosine kinase 0.00426154699 0.010210724715 -3.1145 0.8708 1.0761 1.2863 0.4423 0.4533 0.903323426 GRIP1 glutamate receptor interacting protein 1 3.51435506E-07 2.041141E-06 -3.1149 0.0905 0.1348 0.1255 0.2471 0.0804 0.16676404 SELPLG selectin P ligand 1.99870973E-09 2.11550954E-08 -3.1176 3.6935 2.1936 2.4743 3.0821 2.0265 2.2220401303 ZNF815P zinc finger protein 815, pseudogene 2.31452621E-07 1.40361842E-06 -3.1180 2.0308 2.8349 2.1763 1.6112 2.2056 1.853254067 C21orf49 chromosome 21 open reading frame 49 0.00131702826 0.003566731937 -3.1256 1.4668 4.5126 2.6191 0.7526 2.0249 1.465857509 MTUS1 microtubule associated tumor suppressor 1 6.05133787E-05 0.000217272638 -3.1262 0.8578 1.2199 0.9068 0.7734 1.2179 0.67351393 CRHBP corticotropin releasing hormone binding protein 0.0123377148 0.025956790417 -3.1297 0.1204 0.2488 0.2802 0.2160 0.2956 0.33698853 ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00019627264 0.000631946032 -3.1306 2.2413 1.2794 1.7166 0.9361 0.6873 1.3775643529 LINC00865 long intergenic non-protein coding RNA 865 0.00966005207 0.020972964766 -3.1311 0.0271 0.0507 0.2279 0.1274 0.2383 0.0960205717 KIAA2018 KIAA2018 1.52753295E-15 5.36233287E-13 -3.1334 1.7188 1.3407 1.0172 1.8360 2.5497 1.735926253 CLEC4E C-type lectin domain family 4, member E 0.01762265454 0.035384741068 -3.1339 0.1708 0.0572 0.1168 0.2488 0.0509 0.2558130502 TTC32 tetratricopeptide repeat domain 32 4.91967864E-10 6.39803332E-09 -3.1343 1.8159 2.9635 1.5223 2.5486 4.0788 3.543251276 ZNF571 zinc finger protein 571 2.20776687E-07 1.34647251E-06 -3.1344 0.3709 2.0551 1.8022 0.2243 2.8895 0.8334284367 SIGLEC17P sialic acid binding Ig-like lectin, pseudogene 3 0.01370040368 0.028414730531 -3.1364 0.4024 0.3352 0.7873 0.3819 0.1179 0.4266100130855 USP3-AS1 USP3 antisense RNA 1 4.47413042E-07 2.5247471E-06 -3.1394 1.7279 1.7492 1.5673 1.4403 2.1628 2.13695414 SEPT4 septin 4 0.02600505739 0.049480829803 -3.1479 0.3348 0.3180 0.4502 0.2451 0.2104 0.275051316 PLAC8 placenta-specific 8 0.00017159859 0.000559202685 -3.1486 3.0875 3.3521 2.0148 2.6118 2.7338 2.1771130162 CLHC1 hypothetical protein FLJ31438 3.77203156E-07 2.17647333E-06 -3.1492 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970100505933 ADD3-AS1 ADD3 antisense RNA 1 0.0153264303 0.031333344584 -3.1510 2.5257 1.5449 1.5507 2.9086 1.4579 1.49398660 IRS2 insulin receptor substrate 2 4.90501689E-07 2.73746086E-06 -3.1541 1.7491 2.7277 2.3919 1.6739 2.7262 3.46917745 ZKSCAN8 zinc finger with KRAB and SCAN domains 8 4.95936876E-13 2.65326755E-11 -3.1639 1.7567 1.6713 1.6328 1.3104 2.1071 1.76725624 PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.01475901511 0.030314379957 -3.1644 0.1976 0.3460 0.3253 0.4388 0.0948 0.3843

3592 IL12A 0.02509759083 0.048019181123 -3.1654 1.1215 1.7262 1.2184 1.0642 0.8425 1.188657161 PELI2 pellino E3 ubiquitin protein ligase family member 2 3.96845265E-09 3.86262394E-08 -3.1663 1.4336 1.8218 1.6030 1.2879 2.3956 2.5435729178 STXBP5-AS1 STXBP5 antisense RNA 1 4.09413266E-05 0.000152048764 -3.1697 0.2111 0.2236 0.3076 0.3046 0.2394 0.286123569 PADI4 peptidyl arginine deiminase, type IV 0.00130689345 0.003542435418 -3.1718 0.0388 0.1151 0.0998 0.1813 0.4928 0.1974644511 RPL13AP6 ribosomal protein L13a pseudogene 6 5.56851183E-07 3.07024285E-06 -3.1721 0.3647 0.3642 0.3276 0.3569 0.1923 0.25967556 ZNF10 zinc finger protein 10 2.05952188E-07 1.26876547E-06 -3.1727 0.3332 0.3346 0.3411 0.3938 0.3480 0.426210225 CD96 CD96 molecule 9.86748414E-07 5.14257473E-06 -3.1773 2.8860 3.1723 1.6905 2.7011 1.7067 1.453055112 WDR60 WD repeat domain 60 8.72560206E-12 2.32124351E-10 -3.1789 0.5663 0.4893 0.5531 0.5323 0.5969 0.634051669 TMEM66 transmembrane protein 66 3.41869897E-11 6.925329E-10 -3.1795 1.8450 1.6748 2.0005 1.9413 2.1626 2.118679819 WDR78 WD repeat domain 78 4.22885279E-07 2.40266163E-06 -3.1843 0.5276 0.1140 0.3315 0.2571 0.1203 2.106654882 ANKHD1 ankyrin repeat and KH domain containing 1 2.27708358E-14 3.02856103E-12 -3.1867 0.1686 0.1972 0.1626 0.3309 0.1657 0.201760674 GAS5 growth arrest-specific 5 (non-protein coding) 7.01746589E-09 6.27008003E-08 -3.1871 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970118429 ANTXR2 anthrax toxin receptor 2 1.28993606E-06 6.55989751E-06 -3.1876 2.1529 2.0580 2.1615 1.8295 1.8044 1.9158100132406 NBPF10 neuroblastoma breakpoint family, member 10 3.09692879E-09 3.102362E-08 -3.1891 0.1689 0.1603 0.3354 0.3184 0.1650 0.258110811 NOXA1 NADPH oxidase activator 1 8.50797303E-05 0.000297299069 -3.1894 0.2645 0.2535 1.1185 0.0543 0.1067 1.0861339318 ZNF181 zinc finger protein 181 2.35625462E-08 1.82739747E-07 -3.1894 2.3613 1.7513 1.8136 2.5051 1.9858 2.434284958 SYTL1 synaptotagmin-like 1 2.22165166E-06 1.07278063E-05 -3.1907 1.7072 1.7762 1.8021 1.4455 1.2403 1.6254

390072 OR52N4 0.0125048052 0.026250896215 -3.1927 0.0864 0.1289 0.1370 0.5175 0.0270 0.11674015 LOX lysyl oxidase 0.00012459796 0.000419737093 -3.1943 0.3405 0.6860 0.6934 0.4189 0.3701 0.585422989 MYH15 myosin, heavy chain 15 0.00718550625 0.016149270618 -3.1961 0.0328 0.1566 0.3160 0.1403 0.2121 0.192557545 CC2D2A KIAA1345 protein 0.00461926552 0.010972857459 -3.2035 0.2993 0.4146 0.3009 0.3137 0.2667 0.2031285016 FAM150B hypothetical protein LOC285016 0.00653120641 0.014870804178 -3.2054 1.5596 2.0870 1.0536 1.1038 1.4202 1.074251315 KRCC1 lysine-rich coiled-coil 1 3.82016038E-11 7.56251034E-10 -3.2076 2.1304 1.4622 2.9967 1.8832 1.6279 3.2774100272228 LINC00894 long intergenic non-protein coding RNA 894 2.80716257E-05 0.000107328886 -3.2094 0.2260 0.5629 0.2724 0.4009 0.2427 0.575111337 GABARAP GABA(A) receptor-associated protein 3.64875812E-09 3.58056436E-08 -3.2095 2.3925 1.9436 2.1333 2.7986 3.0018 2.3013379025 FLJ31306 uncharacterized LOC379025 3.41465654E-12 1.1303008E-10 -3.2096 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970100270804 LOC100270804 uncharacterized LOC100270804 0.00246994095 0.006271645514 -3.2105 0.3321 0.3321 0.3321 0.3970 0.3970 0.39707718 ZNF165 zinc finger protein 165 7.59328915E-06 3.27768909E-05 -3.2133 2.0092 2.2291 2.2565 2.0022 2.7467 2.87742323 FLT3LG fms-related tyrosine kinase 3 ligand 6.84649169E-09 6.16555427E-08 -3.2143 1.4158 1.6919 1.8475 1.8406 1.7155 2.29652550 GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.53580467E-07 9.73589802E-07 -3.2166 0.4961 0.7604 0.5535 0.5246 0.8189 0.5465402176 RPL21P44 ribosomal protein L21 pseudogene 44 0.02094739732 0.041094142571 -3.2210 0.1295 0.0727 0.1554 0.3276 0.0648 0.19496169 RPL38 ribosomal protein L38 1.59961118E-12 6.21874374E-11 -3.2214 1.3829 1.4424 1.4669 1.3333 2.6022 1.645254943 DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 0.00025525727 0.000805259132 -3.2251 1.8234 1.6125 1.8523 1.4014 1.7183 2.1568825 CAPN3 calpain 3, (p94) 4.9041804E-07 2.73746086E-06 -3.2253 0.0681 0.1218 0.1912 0.1650 0.1298 0.2100170575 GIMAP1 GTPase, IMAP family member 1 2.06202202E-07 1.26987753E-06 -3.2263 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

27094 KCNMB3 8.59525061E-07 4.54434083E-06 -3.2270 0.1784 0.3310 0.3237 0.3972 0.2106 0.2355

11320 MGAT4A 1.38039125E-09 1.54834309E-08 -3.2273 4.0333 3.3062 2.1392 3.8371 2.8996 2.22203655 ITGA6 integrin, alpha 6 7.12049158E-09 6.34352132E-08 -3.2283 0.8950 1.0167 0.6768 0.7683 0.8721 0.70095530 PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 7.70767479E-11 1.32988323E-09 -3.2291 0.4450 1.8798 0.3032 0.6449 1.2409 0.5698100506321 LOC100506321 uncharacterized LOC100506321 6.33015826E-08 4.41131395E-07 -3.2309 0.4043 0.3454 0.2183 0.5567 0.6760 0.28957503 XIST X inactive specific transcript (non-protein coding) 0.0004416205 0.001319158035 -3.2327 0.1713 0.0706 0.2227 0.4125 0.1406 0.229429765 TMOD4 tropomodulin 4 (muscle) 1.12133621E-05 4.65872107E-05 -3.2345 0.1034 0.0868 0.2114 0.2831 0.0762 0.18024259 MGST3 microsomal glutathione S-transferase 3 1.55398901E-09 1.71257462E-08 -3.2347 2.1215 3.2442 2.0935 2.0272 2.6638 2.833456985 ADPRM chromosome 17 open reading frame 48 7.32006968E-11 1.28238076E-09 -3.2368 3.3496 6.6760 1.0922 1.7882 4.8723 1.8262152110 NEK10 NIMA-related kinase 10 0.01429544733 0.029494852485 -3.2369 0.5759 0.3502 0.3964 0.6579 0.4277 0.4612100130733 LRRC70 leucine rich repeat containing 70 9.50100777E-05 0.000327984912 -3.2381 0.3321 0.3321 0.3321 0.3970 0.3970 0.39704068 SH2D1A SH2 domain containing 1A 7.10714941E-10 8.75079744E-09 -3.2382 1.3268 1.5422 1.9347 1.2359 1.6001 1.7974441951 ZFAS1 ZNFX1 antisense RNA 1 1.81163517E-09 1.95408488E-08 -3.2431 5.6253 1.0312 4.9517 3.4776 3.5051 5.627154514 DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.02622093318 0.04982931784 -3.2433 0.1031 0.0683 0.1438 0.1421 0.1533 0.154479144 PPDPF pancreatic progenitor cell differentiation and proliferation factor 1.13865009E-11 2.88255691E-10 -3.2452 1.2688 2.2612 1.7019 0.9734 2.2841 2.7722

143098 MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 3.3898241E-07 1.97509139E-06 -3.2454 1.2426 1.1145 0.6032 1.2264 1.0220 0.7126388403 YPEL2 yippee-like 2 (Drosophila) 1.03295086E-08 8.78272601E-08 -3.2463 1.1690 3.0799 1.9836 1.2383 3.4291 2.435683449 PMFBP1 polyamine modulated factor 1 binding protein 1 0.0240701103 0.046373793282 -3.2494 0.0400 0.1004 0.2290 0.1776 0.1604 0.198580221 ACSF2 hypothetical protein FLJ20920 6.90675192E-08 4.77127301E-07 -3.2517 1.5728 1.0604 0.9430 1.8722 0.7997 0.9256285540 LOC285540 hypothetical protein LOC285540 0.00185945664 0.004851633843 -3.2521 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970

8233 ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 1.9529054E-09 2.07824621E-08 -3.2527 3.0139 1.7352 1.4175 3.3779 3.1175 2.055850854 C6orf48 chromosome 6 open reading frame 48 7.17663773E-08 4.93904048E-07 -3.2529 0.7316 0.6620 0.6371 0.4951 1.0503 0.56058910 SGCE sarcoglycan, epsilon 0.00344260731 0.008434341751 -3.2584 0.7537 2.3289 1.3496 0.8542 0.4751 1.299411010 GLIPR1 GLI pathogenesis-related 1 6.3507836E-06 2.78210304E-05 -3.2614 3.7563 2.5169 2.0414 3.3315 1.4055 1.347610124 ARL4A ADP-ribosylation factor-like 4A 2.92438306E-09 2.95707401E-08 -3.2614 2.2722 2.1663 2.0502 2.0271 1.9004 2.1477117144 CATSPER1 cation channel, sperm associated 1 0.02612938771 0.049696697441 -3.2631 0.0307 0.1111 0.2421 0.2540 0.0406 0.36476181 RPLP2 ribosomal protein, large, P2 1.83675754E-11 4.24825743E-10 -3.2641 1.2346 2.0054 1.3834 1.7262 3.0455 3.26772635 GBP3 guanylate binding protein 3 0.00020872116 0.000668610268 -3.2643 2.4566 2.7050 2.3760 2.7179 1.6982 2.106123643 LY96 lymphocyte antigen 96 0.00177789612 0.004659454649 -3.2689 1.8179 2.2453 2.4719 1.1515 1.6223 2.0309100287029 DDX11L10 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 10 0.00030460899 0.000945281151 -3.2704 0.3232 0.2956 0.2413 0.2702 0.1219 0.2698130399 ACVR1C activin A receptor, type IC 1.05707613E-06 5.48407014E-06 -3.2707 1.1585 1.3008 1.1224 1.0899 1.1763 1.04907305 TYROBP TYRO protein tyrosine kinase binding protein 0.01032251967 0.022229001693 -3.2712 0.6783 0.3752 0.5416 0.5910 0.2305 0.2321282996 RBM20 RNA binding motif protein 20 0.00216809583 0.005575713871 -3.2723 0.6592 1.7603 1.3151 0.4897 1.0093 0.998110279 PRSS16 protease, serine, 16 (thymus) 0.00024953724 0.000788985037 -3.2731 0.5083 1.2294 0.8460 0.5703 0.7306 1.03128029 CUBN cubilin (intrinsic factor-cobalamin receptor) 1.68585509E-05 6.75376982E-05 -3.2737 0.0688 0.0892 0.3069 0.2606 0.0353 0.2384439949 PRKCQ-AS1 PRKCQ antisense RNA 1 3.67458864E-11 7.35064077E-10 -3.2739 3.6408 3.8015 1.6368 2.5613 3.6461 3.1652100505881 MAGI2-AS3 MAGI2 antisense RNA 3 0.0014944044 0.003994990072 -3.2741 0.5625 0.8199 0.6169 0.3079 1.0076 0.47434671 NAIP NLR family, apoptosis inhibitory protein 7.24472673E-06 3.13760718E-05 -3.2748 0.1008 0.1288 0.2360 0.3075 0.1760 0.213454435 HCG4 HLA complex group 4 (non-protein coding) 0.00954167551 0.020755416062 -3.2754 0.5326 0.6421 0.5451 0.5750 0.5583 0.4469

solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1

interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

olfactory receptor, family 52, subfamily N, member 4,olfactory receptor, family 52, subfamily N, member 4

potassium large conductance calcium-activated channel, subfamily M beta member 3mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A

3001 GZMA 0.003874457 0.009369253338 -3.2783 3.1103 2.5582 1.2949 1.9033 0.9744 0.811010577 NPC2 Niemann-Pick disease, type C2 5.50168996E-06 2.44590946E-05 -3.2785 3.9900 2.4102 3.0849 3.1008 1.2101 1.8022196792 FAM24B family with sequence similarity 24, member B 0.00153873655 0.00410215455 -3.2785 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702332 FMR1 fragile X mental retardation 1 5.27130562E-17 8.75611785E-14 -3.2819 0.5607 0.9690 0.5781 0.6013 1.2974 0.72221316 KLF6 Kruppel-like factor 6 2.72788065E-10 3.92471143E-09 -3.2878 1.6455 2.4042 1.7333 1.8854 2.5628 2.6949153743 PPP1R2P3 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 3 2.53541018E-09 2.60410426E-08 -3.2892 0.0531 0.1247 0.2688 0.4398 0.5697 0.412356034 PDGFC platelet derived growth factor C 0.00659433702 0.014995858882 -3.2922 0.6247 1.1510 0.3490 0.7610 0.4643 0.38716233 RPS27A ribosomal protein S27a 5.85182785E-14 5.51157724E-12 -3.2922 1.1211 2.5094 1.4289 1.0562 1.7033 0.813383938 C10orf11 chromosome 10 open reading frame 11 0.01182614724 0.025007338705 -3.2925 0.0618 0.0940 0.2007 0.1601 0.1762 0.3290283554 GPR137C G protein-coupled receptor 137C 0.02410887661 0.046443583917 -3.2927 2.4746 3.2048 2.5898 1.5384 3.1868 2.35283486 IGFBP3 insulin-like growth factor binding protein 3 0.00194041128 0.005044130729 -3.2961 1.7356 0.8052 0.7180 1.1510 0.7634 0.556710406 WFDC2 WAP four-disulfide core domain 2 0.01783178139 0.035745727871 -3.2962 0.4839 0.7329 0.8000 0.3972 0.4480 0.547959340 HRH4 histamine receptor H4 0.02486304459 0.047650257059 -3.2993 0.1343 0.2070 0.3919 0.2441 0.0768 0.2514115908 CTHRC1 collagen triple helix repeat containing 1 0.00463244735 0.010999516673 -3.3005 0.9037 1.1321 1.0113 0.7634 0.6066 0.814228966 SNX24 sorting nexin 24 2.49250471E-06 1.19069488E-05 -3.3007 2.5115 1.1394 1.9086 1.7916 0.6313 1.9088114915 EPB41L4A-AS1 EPB41L4A antisense RNA 1 4.12328795E-08 3.0136287E-07 -3.3010 0.9650 0.0987 0.4225 0.6674 0.0981 0.3609

56913 C1GALT1 2.44557972E-18 1.48952109E-14 -3.3053 1.2980 1.6512 1.3380 1.3649 2.1407 2.17961950 EGF epidermal growth factor 0.01652334471 0.033419808996 -3.3054 0.1229 0.0818 0.2415 0.4321 0.0513 0.3733

54518 APBB1IP 1.60105359E-11 3.77964486E-10 -3.3069 2.4506 1.8949 2.0346 2.3470 2.0215 2.671654848 ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 0.00057391357 0.001672943942 -3.3089 0.3112 0.0712 0.1910 0.3257 0.0737 0.1838137835 TMEM71 transmembrane protein 71 1.21372908E-06 6.20863876E-06 -3.3151 1.7679 1.6215 0.8926 1.4108 0.9938 0.7360375341 C3orf62 chromosome 3 open reading frame 62 6.86448092E-10 8.4863103E-09 -3.3154 1.1030 0.6951 1.1652 0.8280 0.6018 0.8812386758 ZNF582-AS1 ZNF582 antisense RNA 1 (head to head) 0.00010794669 0.000368329035 -3.3159 0.4998 0.2164 0.9557 0.9853 0.1350 0.21585199 CFP complement factor properdin 3.91830445E-05 0.000146158172 -3.3179 1.8090 2.6455 1.8619 1.1310 0.9101 0.894957460 PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00945107495 0.02058774934 -3.3182 1.4347 1.8009 1.2858 1.9605 1.9362 1.0202387590 TPTEP1 TPTE pseudogene 0.00114318551 0.003139679196 -3.3186 0.7582 1.1681 0.8275 0.7681 0.8275 0.830679820 CATSPERB chromosome 14 open reading frame 161 0.0006252599 0.001807713424 -3.3198 0.0698 0.0729 0.2430 0.2488 0.0640 0.22107581 ZNF33A zinc finger protein 33A 1.04475508E-13 8.22834694E-12 -3.3200 1.1132 1.3916 1.1018 1.1470 1.5835 1.8464473 RERE arginine-glutamic acid dipeptide (RE) repeats 2.5327696E-13 1.61813867E-11 -3.3204 2.1237 1.8870 1.5695 1.6534 1.7103 1.3673285266 ENTPD3-AS1 hypothetical protein FLJ36665 9.89422937E-06 4.16081379E-05 -3.3221 1.8498 2.4400 1.7582 1.7330 3.2694 2.19425906 RAP1A RAP1A, member of RAS oncogene family 3.63464493E-12 1.19406428E-10 -3.3223 1.3230 2.1490 1.2480 1.2427 2.3219 1.393829994 BAZ2B bromodomain adjacent to zinc finger domain, 2B 6.93835966E-11 1.23085153E-09 -3.3223 1.0528 1.0375 0.8153 0.6580 0.8538 0.51711730 DIAPH2 diaphanous-related formin 2 4.36942087E-14 4.71406292E-12 -3.3243 1.0139 1.7475 1.0401 1.2779 1.8988 1.872880145 THOC7 THO complex 7 homolog (Drosophila) 1.97184005E-15 6.00491023E-13 -3.3248 2.9010 4.3946 1.6934 1.5430 4.1991 2.7854139818 DOCK11 dedicator of cytokinesis 11 3.63004202E-15 8.84375036E-13 -3.3259 0.7387 0.7923 1.1921 1.0310 1.0981 1.37141195 CLK1 CDC-like kinase 1 7.04032725E-08 4.85254091E-07 -3.3266 1.5221 1.5239 1.2033 2.2939 3.5208 2.05344504 MT3 metallothionein 3 0.00243763172 0.006198219698 -3.3281 0.9734 1.8232 1.7181 0.9216 1.5435 1.4070401027 C2orf66 IIDS6411 0.00274092905 0.006878485872 -3.3307 0.1424 0.0619 0.1243 0.3854 0.0592 0.192755450 CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 8.13088808E-06 3.4817808E-05 -3.3318 1.1441 2.1713 2.4584 0.9054 1.0364 2.186751439 FAM8A1 family with sequence similarity 8, member A1 6.31606293E-13 3.06933782E-11 -3.3321 1.2843 3.7810 1.2329 1.2151 3.4165 1.800692126 DSEL dermatan sulfate epimerase-like 0.00026516243 0.000834202461 -3.3351 2.6419 1.4902 1.8513 1.6013 0.3171 1.0526387751 GVINP1 GTPase, very large interferon inducible pseudogene 1 4.82328027E-09 4.57692384E-08 -3.3392 0.9001 2.0722 0.4465 0.9294 0.9240 0.4040486 FXYD2 FXYD domain containing ion transport regulator 2 0.00719207381 0.016156082205 -3.3392 0.5664 0.6767 1.0747 0.4177 0.4491 0.6378400221 FLJ22447 uncharacterized LOC400221 0.01033980547 0.022263601885 -3.3423 1.0684 0.8064 1.5090 0.6079 0.3400 0.7073100306951 PITPNA-AS1 PITPNA antisense RNA 1 5.64683703E-09 5.22954922E-08 -3.3425 0.2558 6.8445 0.8737 0.0346 2.3300 2.023654543 TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 5.6082202E-13 2.92781141E-11 -3.3426 2.7625 2.6410 1.8298 2.7578 3.2536 1.80444093 SMAD9 SMAD family member 9 0.00016988179 0.000554696232 -3.3436 0.1703 1.4475 0.5597 0.2856 0.4139 0.5533100462977 MTRNR2L1 MT-RNR2-like 1 0.02418250518 0.04656087825 -3.3453 0.0108 0.0026 0.0287 0.1969 0.0359 0.3752285051 C2orf61 hypothetical protein FLJ40172 4.30694565E-05 0.000159111425 -3.3474 0.2300 0.3079 0.4058 0.2645 0.2539 0.30157433 VIPR1 vasoactive intestinal peptide receptor 1 5.29568149E-07 2.93398097E-06 -3.3504 0.7306 0.7023 0.8081 0.8262 0.7414 0.71133816 KLK1 kallikrein 1 0.01892558229 0.037621547775 -3.3508 0.0761 0.0298 0.1992 0.1783 0.0887 0.19809586 CREB5 cAMP responsive element binding protein 5 0.00306454573 0.00761117026 -3.3570 0.3857 0.3998 0.4204 0.3482 0.2201 0.2899401466 C8orf59 chromosome 8 open reading frame 59 3.27083493E-14 3.94212699E-12 -3.3585 0.6802 1.9674 1.7953 0.5244 1.5067 1.4411643770 LOC643770 uncharacterized LOC643770 0.00091269476 0.002559355219 -3.3600 2.0539 1.6769 2.0800 2.6211 2.3491 2.998757453 DSCAML1 Down syndrome cell adhesion molecule like 1 0.00615416637 0.014101947318 -3.3600 0.7041 1.0943 1.2827 0.4707 0.3268 0.64114211 MEIS1 Meis homeobox 1 0.00307157464 0.007626554128 -3.3619 0.7133 0.8666 0.6111 0.4861 0.6765 0.427391937 TIMD4 T-cell immunoglobulin and mucin domain containing 4 1.42374606E-07 9.08839586E-07 -3.3642 0.2364 0.0816 0.3648 0.1787 0.0914 0.2853201229 LYRM9 hypothetical protein LOC201229 2.02734625E-07 1.25063034E-06 -3.3702 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702815 GP9 glycoprotein IX (platelet) 0.00114884121 0.003154263951 -3.3712 0.1384 0.2291 0.1752 0.0830 0.6680 0.15119168 TMSB10 thymosin beta 10 2.38047468E-08 1.84305226E-07 -3.3717 1.6605 1.6838 1.9320 1.8826 1.6177 2.529723648 SSBP3 single stranded DNA binding protein 3 9.99412667E-12 2.59393015E-10 -3.3727 1.2436 2.0377 0.8720 1.6315 2.1953 2.348251062 ATL1 atlastin GTPase 1 3.19090037E-05 0.000120537795 -3.3750 0.7301 0.6597 0.6707 0.4952 0.6416 0.5279442421 PTGER4P2-CDK PTGER4P2-CDK2AP2P2 readthrough transcribed pseudogene 0.00577398112 0.013339509803 -3.3761 0.1641 0.1117 0.2889 0.2973 0.1183 0.2139254065 BRWD3 bromodomain and WD repeat domain containing 3 3.41472575E-13 2.01921906E-11 -3.3788 1.0650 1.5038 1.1097 1.2337 2.3414 1.8222283971 CLEC18C hypothetical protein MGC34761 0.01011249228 0.021843652797 -3.3801 0.1740 0.2277 0.2224 0.2601 0.2014 0.2886100652768 LOC100652768 uncharacterized LOC100652768 0.00078156052 0.002217840325 -3.3813 0.0721 0.4030 0.1743 0.0767 0.3954 0.20936228 RPS23 ribosomal protein S23 7.16218789E-14 6.35279113E-12 -3.3814 2.5896 2.6753 1.6346 2.9765 6.0758 2.74271806 DPYD down-regulator of transcription 1, TBP-binding (negative cofactor 2) 2.39392497E-08 1.85199756E-07 -3.3821 2.5635 3.2272 1.9892 2.9750 3.2606 3.06036160 RPL31 ribosomal protein L31 1.05564252E-12 4.50670562E-11 -3.3852 1.5937 2.0902 1.4313 1.6193 3.1570 2.50565324 PLAG1 pleiomorphic adenoma gene 1 7.63330705E-09 6.72820967E-08 -3.3854 0.9004 2.8424 0.9594 0.7953 3.3187 1.6422285596 FAM153A family with sequence similarity 153, member A 1.68789086E-05 6.76044319E-05 -3.3855 0.7656 1.0023 0.7395 0.6246 1.4036 0.7016221264 AK9 chromosome 6 open reading frame 199 4.45651845E-08 3.2236542E-07 -3.3871 0.7275 0.3608 0.2436 0.4256 0.5025 0.2185383 ARG1 arginase 1 0.00621511952 0.014229127152 -3.3916 0.0292 0.0418 0.2320 0.1871 0.0241 0.14854050 LTB lymphotoxin beta (TNF superfamily, member 3) 1.6661701E-05 6.68516912E-05 -3.3925 0.5302 0.6077 0.5984 0.6537 0.6629 0.6989729444 LOC729444 uncharacterized LOC729444 0.01491732034 0.030614475593 -3.3933 0.0886 0.0588 0.0828 0.4878 0.3323 0.15727694 ZNF135 zinc finger protein 135 0.00243098193 0.006183892774 -3.3987 0.9726 1.1692 1.1704 1.2361 2.4287 1.20246399 TRAPPC2 trafficking protein particle complex 2 9.21680536E-15 1.6019917E-12 -3.3996 1.0707 5.0430 3.3679 0.0617 5.9821 1.08342745 GLRX glutaredoxin (thioltransferase) 4.32343957E-08 3.14482037E-07 -3.4008 4.4733 3.3598 2.5137 4.4866 3.4813 2.0738133418 EMB embigin 4.46438879E-12 1.39919918E-10 -3.4030 1.0197 1.1798 0.9241 0.9019 0.9436 0.8614100506311 HOTAIRM1 HOXA transcript antisense RNA, myeloid-specific 1 6.15306994E-08 4.30432213E-07 -3.4065 3.3617 1.6724 1.0619 1.5113 0.8125 1.293927197 GPR82 G protein-coupled receptor 82 0.00721064009 0.016191817105 -3.4087 0.1615 0.1766 0.4460 0.0831 0.2127 0.17251032 CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 1.18244805E-10 1.91031748E-09 -3.4093 2.1130 2.7769 1.6728 2.0975 2.2527 2.361726266 SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 0.00791038758 0.017598758291 -3.4121 0.0361 0.0159 0.1524 0.2593 0.0318 0.188391584 PLXNA4 plexin A4 0.00024214666 0.000767077623 -3.4123 0.4002 0.8207 0.4464 0.4008 0.7553 0.2183

115294 PCMTD1 6.18966578E-11 1.12311393E-09 -3.4133 0.6645 1.3046 0.6837 0.8340 1.5965 1.01216493 SIM2 single-minded family bHLH transcription factor 2 0.00887626862 0.019460904756 -3.4143 1.6003 0.7467 1.3050 0.5419 1.1213 0.6081728621 CCDC30 hypothetical protein LOC728621 2.91659613E-07 1.7268971E-06 -3.4145 0.5081 0.3690 0.3839 0.4337 0.3464 0.280951673 TPPP3 tubulin polymerization-promoting protein family member 3 0.00429362091 0.010276793449 -3.4151 0.5285 0.8486 0.7753 0.4658 0.2379 0.5859256643 CXorf23 chromosome X open reading frame 23 2.36550232E-08 1.83379119E-07 -3.4164 0.1569 0.2216 0.4031 0.3576 0.3843 0.12752099 ESR1 estrogen receptor 1 0.00472919509 0.011204856424 -3.4174 0.5754 0.6202 0.4302 0.6205 0.4504 0.33888115 TCL1A T-cell leukemia/lymphoma 1A 0.02538924798 0.048480754423 -3.4191 0.0764 0.0416 0.3531 0.1143 0.0258 0.1751342184 FMN1 formin 1 0.00034478196 0.001056845479 -3.4240 1.9318 1.8192 1.6258 1.2844 1.0636 1.0257554235 ASPDH hypothetical protein LOC554235 0.00898617526 0.019682977026 -3.4245 0.1061 0.2005 0.3472 0.1894 0.0644 0.389127244 SESN1 sestrin 1 9.12569983E-09 7.88764367E-08 -3.4278 2.7204 2.7024 1.5534 2.4734 3.3268 1.82539648 GCC2 GRIP and coiled-coil domain containing 2 1.61730532E-12 6.27418319E-11 -3.4280 2.0894 3.8331 1.6323 2.5090 4.2346 2.46264005 LMO2 LIM domain only 2 (rhombotin-like 1) 0.00491818403 0.011593533578 -3.4326 0.7063 1.0279 0.6677 0.6086 0.5785 0.459310803 CCR9 chemokine (C-C motif) receptor 9 0.00074480195 0.002122430016 -3.4337 0.4794 0.2732 0.2437 0.3831 0.2411 0.2250222901 RPL23P8 similar to ribosomal protein L23 2.73437341E-08 2.08437509E-07 -3.4342 0.0414 0.0227 0.1630 0.2441 0.1313 0.06653081 HGD homogentisate 1,2-dioxygenase 0.00040769219 0.001229671799 -3.4361 0.0523 0.2089 0.0849 0.2303 0.1637 0.2097375298 CERKL ceramide kinase-like 2.38453507E-06 1.14387569E-05 -3.4402 0.3224 0.5342 0.4707 0.4652 0.4288 0.349655000 TUG1 taurine up-regulated 1 (non-protein coding) 1.00369077E-14 1.67753666E-12 -3.4415 1.2522 1.2900 1.3867 1.6755 1.3900 1.87815197 PF4V1 platelet factor 4 variant 1 0.00129142681 0.003502590276 -3.4427 0.2395 0.0436 0.2512 0.3366 0.0427 0.209455061 SUSD4 sushi domain containing 4 0.00016979721 0.000554519149 -3.4433 1.9623 0.9863 1.4987 1.4568 0.6027 1.1129390535 GOLGA8EP golgin A8 family, member E, pseudogene 0.00727859913 0.016324360288 -3.4452 0.0247 0.0240 0.2141 0.2463 0.0889 0.201729998 GLTSCR1 glioma tumor suppressor candidate region gene 1 9.36955751E-11 1.56920765E-09 -3.4459 0.6848 0.5874 0.8714 0.5374 0.9850 1.350655356 SLC22A15 solute carrier family 22, member 15 0.01398165464 0.028938920876 -3.4460 0.8192 2.1603 1.4452 0.6501 1.4256 1.4062374786 EFCAB5 EF-hand calcium binding domain 5 0.00422421233 0.010135890702 -3.4463 8.9219 1.1030 0.4104 16.5289 0.8586 0.22798436 SDPR serum deprivation response 0.00193478628 0.00503237222 -3.4480 0.2418 1.0387 0.5658 0.3002 0.7080 0.3315390212 GPR152 G protein-coupled receptor 152 0.00957886238 0.020821433909 -3.4504 0.1179 0.0370 0.1796 0.0871 0.0509 0.359354981 NMRK1 nicotinamide riboside kinase 1 8.56661621E-10 1.0250767E-08 -3.4528 9.2791 6.7801 1.6761 6.7724 10.3068 1.662122834 ZNF652 zinc finger protein 652 4.56178205E-11 8.72805043E-10 -3.4544 1.5123 1.9012 1.3112 1.4909 2.0300 2.0278728743 LOC728743 zinc finger protein pseudogene 2.29239478E-08 1.78621055E-07 -3.4556 1.3886 1.5760 1.6838 1.0727 1.2293 1.403954558 SPATA6 spermatogenesis associated 6 2.19659697E-05 8.58161639E-05 -3.4558 1.4041 1.7777 1.6176 1.1928 1.7404 1.325010003 NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 6.83803628E-05 0.000243082877 -3.4570 0.8589 1.1446 0.6936 1.1594 0.3173 0.442390737 PAGE5 P antigen family, member 5 (prostate associated) 9.03634423E-05 0.000313371957 -3.4570 0.1178 0.0832 0.1226 0.2045 0.0957 0.270090024 FLJ20021 uncharacterized LOC90024 2.91447091E-06 1.37109198E-05 -3.4582 3.7466 3.1118 4.6641 2.1449 1.7390 4.56915874 RAB27B RAB27B, member RAS oncogene family 0.00054221332 0.001588730234 -3.4618 1.6768 2.7484 1.3401 1.5557 1.4705 0.8783152189 CMTM8 CKLF-like MARVEL transmembrane domain containing 8 2.92113028E-10 4.1504582E-09 -3.4619 1.2825 2.3944 1.9291 1.1827 2.4172 2.086155914 ERBB2IP erbb2 interacting protein 2.24760004E-14 3.02856103E-12 -3.4635 1.5588 1.5531 0.9853 2.3583 2.1967 2.101626996 GPR160 G protein-coupled receptor 160 7.90915829E-08 5.38435694E-07 -3.4640 1.6644 1.2899 1.3090 1.2649 1.1146 1.30074222 MEOX1 mesenchyme homeobox 1 0.00605816563 0.013913373857 -3.4674 1.1927 0.5515 1.5159 0.7005 0.2420 0.8316139201 MAP2K4P1 mitogen-activated protein kinase kinase 4 pseudogene 1 0.0025101783 0.006362321807 -3.4758 0.8690 0.3244 0.4925 0.2017 0.1799 0.0812100240735 LOC100240735 uncharacterized LOC100240735 0.0013769842 0.00370788592 -3.4767 4.0942 1.9740 2.4599 2.9834 1.0518 1.65131089 CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 0.00821348436 0.018197742959 -3.4782 0.2906 0.5805 0.1554 0.3983 0.1359 0.1946120 ADD3 adducin 3 (gamma) 2.79011292E-11 5.94183488E-10 -3.4785 0.5216 0.5413 0.6071 0.3996 0.2443 0.391010235 RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 3.0225943E-07 1.78215047E-06 -3.4802 0.9869 1.7161 1.4793 1.1264 1.7270 1.277423036 ZNF292 zinc finger protein 292 1.54616586E-16 1.41500021E-13 -3.4857 2.3420 2.3295 2.1320 1.7294 3.5974 2.1908166929 SGMS2 sphingomyelin synthase 2 0.00272420037 0.00684120246 -3.4859 0.2889 0.6533 0.7426 0.2728 0.7839 0.5733645528 LINC00264 long intergenic non-protein coding RNA 264 0.02115265356 0.041462096303 -3.4867 0.0503 0.0916 0.1077 0.2256 0.2988 0.1933969 CD69 CD69 molecule 3.36734165E-08 2.50114092E-07 -3.4871 2.5923 1.3752 1.6376 3.4970 3.0684 2.0316

729230 CCR2 0.02126893776 0.041639990437 -3.4898 1.9711 0.3581 0.8781 0.7489 0.3228 0.426880863 PRRT1 proline-rich transmembrane protein 1 2.98530666E-05 0.000113404414 -3.4929 0.5666 0.6792 0.4847 0.5312 0.5090 0.4545729723 DNAJC27-AS1 DNAJC27 antisense RNA 1 0.00147468421 0.003948048346 -3.4930 0.3564 0.0763 0.3441 0.3750 0.0838 0.42081556 CYP2B7P1 cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene 0.00432057211 0.01033588552 -3.4945 0.0629 0.0118 0.1352 0.2445 0.0592 0.24497100 TLR5 toll-like receptor 5 0.00065112767 0.001873902147 -3.4947 1.0393 1.1704 1.2024 0.7970 0.9081 0.95046230 RPS25 ribosomal protein S25 2.58009636E-13 1.63126369E-11 -3.4956 1.9237 5.4977 2.7335 2.2651 12.2787 2.610192797 HELB helicase (DNA) B 5.49746546E-14 5.34306856E-12 -3.4969 2.9718 2.2268 1.3458 3.3792 2.6606 2.5523343413 FCRL6 Fc receptor-like 6 0.02085515169 0.040952749234 -3.4970 0.4896 0.2249 0.3657 0.3885 0.2425 0.2483

granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)

core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1

amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1

similar to C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD192 antigen)

23108 RAP1GAP2 RAP1 GTPase activating protein 2 4.35206413E-07 2.4680607E-06 -3.5005 1.6131 2.3081 1.8048 1.1057 1.5316 0.8461641638 SNHG6 small nucleolar RNA host gene 6 (non-protein coding) 1.52079655E-12 6.02776456E-11 -3.5005 2.6243 2.2862 1.4515 2.3687 3.6056 2.38372944 GSTM1 glutathione S-transferase mu 1 7.6553495E-07 4.09360685E-06 -3.5012 0.6904 0.5866 0.6089 0.7812 0.1694 0.70733727 JUND jun D proto-oncogene 3.12247084E-10 4.37864829E-09 -3.5024 0.4105 2.1118 1.2273 0.9886 4.0575 3.1464863 CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.00276623946 0.006934384343 -3.5030 0.2474 0.4963 0.2272 0.3738 0.2553 0.16701380 CR2 complement component (3d/Epstein Barr virus) receptor 2 0.00039610426 0.001198082594 -3.5031 1.0610 0.7167 0.7668 0.8348 0.7698 0.6242100507250 LOC100507250 uncharacterized LOC100507250 1.78148172E-05 7.09641028E-05 -3.5034 0.8373 0.6689 1.8684 1.1272 0.7349 1.054427035 NOX1 NADPH oxidase 1 0.00160861046 0.004268447625 -3.5073 0.0031 0.0572 0.1826 0.0200 0.0367 0.131511191 PTENP1 phosphatase and tensin homolog pseudogene 1 (functional) 3.72774074E-12 1.21198005E-10 -3.5082 1.0175 0.5520 1.2417 0.7594 0.5253 0.980981629 TSSK3 testis-specific serine kinase 3 2.14112837E-07 1.31152188E-06 -3.5095 0.3321 0.3321 0.3321 0.3371 0.4065 0.32746146 RPL22 ribosomal protein L22 8.84712078E-15 1.58061002E-12 -3.5095 2.7351 2.0607 1.6388 2.3365 3.2302 1.9828200958 MUC20 mucin 20, cell surface associated 2.71392257E-07 1.6184332E-06 -3.5118 0.0924 0.0701 0.2681 0.2082 0.1272 0.292755970 GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.0088709517 0.019456251286 -3.5162 0.3006 0.6394 0.8375 0.7066 0.2454 0.7108143689 PIWIL4 piwi-like RNA-mediated gene silencing 4 1.12955386E-05 4.68859793E-05 -3.5233 0.5760 0.9143 1.0603 0.4267 1.1655 0.6214286006 LSMEM1 hypothetical protein FLJ39575 0.00019035266 0.000614400955 -3.5258 0.0512 0.0410 0.1875 0.1498 0.0211 0.13545196 PF4 platelet factor 4 0.00014730477 0.000487345206 -3.5307 0.2653 0.1393 0.2437 0.3550 0.1612 0.340455769 ZNF83 zinc finger protein 83 9.88925892E-10 1.15756912E-08 -3.5310 1.4674 1.7578 1.1836 1.4772 2.2594 1.39312263 FGFR2 fibroblast growth factor receptor 2 0.01977730044 0.03906905449 -3.5347 0.0748 0.1247 0.2739 0.2101 0.1236 0.1806199 AIF1 allograft inflammatory factor 1 4.48322953E-05 0.000165089822 -3.5381 0.5060 0.5416 0.6190 0.5005 0.5553 0.53436164 RPL34 ribosomal protein L34 9.96342263E-14 7.94985408E-12 -3.5386 3.4673 3.8545 2.7898 1.3228 7.6801 2.8006283232 TMEM80 transmembrane protein 80 8.95181346E-10 1.06558655E-08 -3.5396 1.7304 2.7932 1.4645 2.9710 3.7992 2.32787178 TPT1 tumor protein, translationally-controlled 1 6.38225613E-12 1.85695197E-10 -3.5411 1.9814 8.5141 2.2025 2.6962 20.0061 3.67689760 TOX thymocyte selection-associated high mobility group box 6.40729341E-08 4.458266E-07 -3.5424 2.3113 1.9082 2.2133 2.7970 2.4260 2.8681162394 SLFN5 schlafen family member 5 8.71523118E-08 5.86536664E-07 -3.5426 2.0830 2.7355 2.5215 3.6205 3.3083 3.920964224 HERPUD2 HERPUD family member 2 3.5719857E-11 7.17223326E-10 -3.5457 2.2250 4.3597 2.3337 1.8074 6.6954 3.772755103 RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 3.72952994E-07 2.15447269E-06 -3.5467 0.9474 1.1560 1.1741 0.9454 1.2108 1.591327113 BBC3 BCL2 binding component 3 3.56330725E-08 2.63171989E-07 -3.5500 1.0034 1.0017 1.6719 0.6286 0.9296 1.3446441818 WBP11P1 WW domain binding protein 11 pseudogene 1 3.34547951E-07 1.9523667E-06 -3.5512 0.0672 0.1231 0.2608 0.2376 0.0840 0.2642150786 WTH3DI RAB6C-like 2.85820835E-11 6.06564262E-10 -3.5515 0.5293 0.9868 1.0217 0.5797 0.8838 0.5268100379661 GRIK1-AS2 GRIK1 antisense RNA 2 6.79317656E-06 2.95746777E-05 -3.5547 0.0312 0.0855 0.0837 0.2127 0.0273 0.170984969 TOX2 TOX high mobility group box family member 2 1.65892321E-05 6.65901688E-05 -3.5557 0.6719 0.7198 0.9562 0.4302 0.4512 0.82905608 MAP2K6 mitogen-activated protein kinase kinase 6 9.13470811E-08 6.11165824E-07 -3.5564 1.5302 1.7599 1.0909 1.6458 1.1640 0.9498120892 LRRK2 leucine-rich repeat kinase 2 0.01935822814 0.038359704678 -3.5574 0.1375 0.1974 0.3064 0.2771 0.2096 0.2319

58473 PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 1.31391297E-07 8.44156744E-07 -3.5579 0.4584 0.3863 0.4434 0.3479 0.2213 0.246727115 PDE7B phosphodiesterase 7B 0.00026156782 0.000824170932 -3.5586 1.3023 1.1753 1.1142 1.0183 0.8780 0.76092252 FGF7 fibroblast growth factor 7 0.01527370922 0.031248596455 -3.5596 0.3316 0.2769 0.1535 0.4340 0.2058 0.1412346007 EYS eyes shut homolog (Drosophila) 9.8894383E-08 6.55421896E-07 -3.5615 0.0398 0.0216 0.0905 0.2574 0.0122 0.104455729 ATF7IP activating transcription factor 7 interacting protein 2.05248688E-12 7.57637178E-11 -3.5617 1.8479 1.9679 0.9661 1.3210 1.4905 0.86932681 GGTA1P glycoprotein, alpha-galactosyltransferase 1 pseudogene 0.00756687721 0.016914849578 -3.5621 0.5473 1.1331 0.6324 0.3646 0.7051 0.599264283 ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.01949127838 0.038589732206 -3.5638 0.1621 0.2492 0.2841 0.3089 0.1659 0.2211401262 CRIP3 cysteine-rich protein 3 0.00090933177 0.002551099358 -3.5678 1.3655 1.7288 1.9509 0.6343 1.1809 1.3186

284111 SLC13A5 0.00175698558 0.004612592034 -3.5694 0.2954 1.1208 0.3641 0.2714 0.3423 0.2733216 ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.01037732369 0.022331228185 -3.5702 0.2054 0.3635 0.0863 0.2931 0.2435 0.086010002 NR2E3 nuclear receptor subfamily 2, group E, member 3 0.01408194595 0.029133301224 -3.5703 0.0772 0.0670 0.1994 0.2621 0.0259 0.1867163255 ZNF540 zinc finger protein 540 1.12933718E-05 4.68859793E-05 -3.5711 3.9071 0.6265 0.4652 1.7230 0.2938 0.355691050 CCDC149 hypothetical protein DKFZp761B107 0.02227558075 0.043299937386 -3.5779 0.5767 0.5353 0.4514 0.5999 0.1561 0.431480310 PDGFD platelet derived growth factor D 0.0033609502 0.008249769207 -3.5812 0.6019 0.2683 0.3489 0.4219 0.3460 0.6502100505622 LOC100505622 uncharacterized LOC100505622 2.4892336E-06 1.19003863E-05 -3.5841 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970122525 C14orf28 chromosome 14 open reading frame 28 1.29340925E-07 8.32154005E-07 -3.5843 1.0565 0.9776 0.6489 1.1450 1.1546 0.76489901 SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 7.35093926E-07 3.94699859E-06 -3.5854 0.8077 1.0039 0.7887 0.8297 0.6898 0.630255667 DENND4C DENN/MADD domain containing 4C 4.55267958E-14 4.76715125E-12 -3.5856 0.6000 0.5818 0.3666 0.5425 0.8083 0.5433374650 GOLGA6L5 golgin A6 family-like 5 (pseudogene) 6.37705886E-09 5.79133298E-08 -3.5860 0.1255 0.0920 0.3172 0.5043 0.0289 0.269651274 KLF3 Kruppel-like factor 3 (basic) 1.64916681E-08 1.33373543E-07 -3.5863 1.6920 2.3089 2.0609 1.5847 2.3698 2.8121951 CD37 CD37 molecule 2.28415365E-12 8.11985514E-11 -3.5879 2.0639 1.6921 2.6920 1.6768 2.0501 2.5821285908 LINC00174 hypothetical protein LOC285908 3.0562268E-05 0.000115881668 -3.5880 0.0902 0.0259 0.2081 0.1136 0.0162 0.276284795 PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2 1.6652211E-06 8.27943401E-06 -3.5881 0.6905 1.0380 0.6047 0.7578 0.8091 0.31326210 RPS15A ribosomal protein S15a 7.15028544E-13 3.3935069E-11 -3.5883 2.3649 1.0871 2.1952 2.3748 1.5250 2.901026115 TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 2.42184462E-09 2.50293805E-08 -3.5886 0.0960 0.0800 0.1473 0.1935 0.1274 0.1955347051 SLC10A5 solute carrier family 10, member 5 0.01242929542 0.026110380072 -3.5901 0.2636 0.1205 0.2567 0.5070 0.1162 0.176410638 SPHAR S-phase response (cyclin related) 8.06241208E-06 3.45731973E-05 -3.5927 0.0988 0.1882 0.2481 0.1746 0.1651 0.198454413 NLGN3 neuroligin 3 1.42404101E-07 9.08839586E-07 -3.5976 0.2565 0.2994 0.3925 0.2460 0.2987 0.291464072 CDH23 cadherin-like 23 7.8202396E-06 3.36452597E-05 -3.5978 0.5898 0.7138 0.5758 0.4996 0.5002 0.4225153241 CEP120 coiled-coil domain containing 100 2.81608382E-12 9.63585835E-11 -3.5984 2.0493 1.7118 1.6980 2.2178 1.6327 1.9654474338 SUMO1P3 SUMO1 pseudogene 3 1.61561746E-13 1.15314696E-11 -3.6021 0.1208 0.1315 0.2200 0.4076 0.2200 0.41846451 SH3BGRL SH3 domain binding glutamate-rich protein like 3.33886781E-11 6.78618383E-10 -3.6030 2.4607 2.6867 2.1084 1.6808 1.6147 1.9233285456 RPL34-AS1 hypothetical protein FLJ37673 0.00155566787 0.004141195114 -3.6079 2.3557 1.7268 4.1637 1.5473 0.8227 1.435680115 BAIAP2L2 BAI1-associated protein 2-like 2 0.00031444887 0.000973007566 -3.6088 0.0343 0.0998 0.1413 0.1328 0.1840 0.1832100129550 LOC100129550 uncharacterized LOC100129550 6.9073846E-09 6.19596129E-08 -3.6091 0.0452 0.0921 0.1383 0.1256 0.0377 0.190791663 MYADM myeloid-associated differentiation marker 5.29663229E-09 4.94532781E-08 -3.6098 1.8507 2.3416 2.0520 1.9678 2.2793 2.1491257044 C1orf101 chromosome 1 open reading frame 101 0.02002576204 0.039498135137 -3.6120 0.9468 1.2155 0.9520 1.0895 1.1447 0.85731776 DNASE1L3 dynein, cytoplasmic 1, heavy chain 1 0.00062447074 0.001806003389 -3.6138 0.1749 0.7050 1.0050 0.2118 0.2705 0.484828951 TRIB2 tribbles pseudokinase 2 6.33518088E-07 3.44923793E-06 -3.6151 2.0656 2.1736 1.9705 1.8269 2.0072 2.3685154664 ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 0.01054674962 0.022626536227 -3.6154 0.0765 0.0649 0.1476 0.2219 0.1080 0.165625789 TMEM59L transmembrane protein 59-like 0.01412630057 0.029195313203 -3.6169 0.6790 2.8225 1.2940 0.6085 1.7270 1.0526

123041 SLC24A4 0.01420791783 0.029340763401 -3.6172 0.1395 0.1797 0.2956 0.1683 0.1002 0.2442160365 CLECL1 dendritic cell-associated lectin-1 1.60134731E-06 7.99696115E-06 -3.6183 0.6407 0.7963 1.0738 0.6725 0.2610 0.5643153769 SH3RF2 SH3 domain containing ring finger 2 0.02032379561 0.040003920442 -3.6204 0.1219 0.1411 0.2631 0.1641 0.1030 0.2727642976 GRIK1-AS1 GRIK1 antisense RNA 1 0.02520889646 0.048191771934 -3.6205 0.1149 0.0031 0.1166 0.2211 0.0185 0.23471942 EFNA1 ephrin-A1 0.00035138701 0.001073669488 -3.6208 1.9612 3.4785 2.2905 1.2713 2.2123 1.6904100131434 LINC00893 long intergenic non-protein coding RNA 893 2.61616611E-05 0.000100531203 -3.6243 0.9336 0.7827 2.0487 0.7325 0.5501 1.8954100507433 ZNF571-AS1 ZNF571 antisense RNA 1 0.00017827124 0.000579088386 -3.6276 0.1893 0.3684 0.2884 0.3409 0.2682 0.3088119032 C10orf32 chromosome 10 open reading frame 32 9.15500302E-13 4.03084856E-11 -3.6277 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970375287 RBM43 RNA binding motif protein 43 1.61308623E-05 6.48357052E-05 -3.6308 2.9867 2.3311 1.6897 3.2907 1.9359 1.829610424 PGRMC2 progesterone receptor membrane component 2 7.47746312E-15 1.4691205E-12 -3.6315 1.6698 1.3220 1.8269 1.4361 0.9130 2.4593729041 LOC729041 fatty acid amide hydrolase pseudogene 0.00401495818 0.009685940823 -3.6315 0.0516 0.0103 0.0327 0.0984 0.0662 0.2664653160 LOC653160 uncharacterized LOC653160 8.6420854E-08 5.82472093E-07 -3.6350 0.2399 0.2940 0.3757 0.3286 0.2667 0.35546173 RPL36A ribosomal protein L36a 5.95200046E-12 1.75685289E-10 -3.6375 0.3321 0.3321 0.3321 0.3970 0.3970 0.39701880 GPR183 endothelin converting enzyme 1 2.34203825E-08 1.81982041E-07 -3.6423 2.0402 1.7994 2.0236 3.3918 1.9722 1.68636678 SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00066268993 0.001904777466 -3.6432 0.2711 0.2394 0.4535 0.3279 0.0992 0.339111147 HHLA3 HERV-H LTR-associating 3 1.22217143E-08 1.01970395E-07 -3.6474 4.2599 0.3466 0.5514 0.4170 2.9330 0.1384201134 CEP112 coiled-coil domain containing 46 0.0017476364 0.004591346113 -3.6496 0.4648 0.3911 0.5827 0.3290 0.3061 0.45635920 RARRES3 retinoic acid receptor responder (tazarotene induced) 3 9.93804622E-05 0.000341780502 -3.6507 2.8806 1.9822 3.6109 2.6378 1.3484 2.2905497258 BDNF-AS brain-derived neurotrophic factor opposite strand 6.64163252E-06 2.90116924E-05 -3.6511 1.1876 1.0880 0.4185 0.7695 0.8304 0.343555283 MCOLN3 mucolipin 3 0.00014927923 0.000493242332 -3.6519 0.2752 0.3886 0.6116 0.4206 0.1854 0.53361356 CP ceruloplasmin (ferroxidase) 0.00885039602 0.019418159942 -3.6542 0.0738 0.1077 0.1240 0.1836 0.1910 0.14861028 CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 4.77644916E-07 2.67797727E-06 -3.6549 0.9885 1.5901 1.3484 0.5456 0.7034 1.61107381 UQCRB ubiquinol-cytochrome c reductase binding protein 4.99710861E-17 8.75611785E-14 -3.6552 2.5300 1.9433 1.4747 2.4529 3.4001 2.12158722 CTSF cathepsin F 1.37537446E-06 6.96338103E-06 -3.6556 0.6799 1.3228 1.1802 0.5330 0.6108 0.865611126 CD160 CD160 molecule 8.14407796E-06 3.48661182E-05 -3.6581 0.1292 0.1561 0.4525 0.2552 0.0799 0.31038905 AP1S2 adaptor-related protein complex 1, sigma 2 subunit 1.04415405E-09 1.21520909E-08 -3.6612 1.3899 1.9003 1.4052 1.4514 1.7060 1.67631572 CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 0.01094276318 0.023360926379 -3.6613 0.0458 0.1375 0.2171 0.1740 0.0154 0.228964407 RGS18 regulator of G-protein signaling 18 4.0061342E-05 0.00014899264 -3.6614 0.1467 0.0525 0.1014 0.3248 0.0375 0.101911278 KLF12 Kruppel-like factor 12 3.88641687E-12 1.25463974E-10 -3.6642 2.1816 2.5728 1.6019 2.8577 3.3932 3.242327185 DISC1 disrupted in schizophrenia 1 0.00055390871 0.001619622318 -3.6653 2.4123 1.5216 1.9201 2.0958 1.9752 2.020183853 ROPN1L rhophilin associated tail protein 1-like 0.00645762354 0.014725283588 -3.6682 0.2575 2.2318 0.1208 0.3801 0.3691 0.1519347 APOD apolipoprotein D 0.02534999072 0.048428454222 -3.6716 0.1829 0.2388 0.8675 0.1960 0.2513 0.55392841 GPR18 G protein-coupled receptor 18 6.55140551E-08 4.54987767E-07 -3.6755 3.6788 2.1937 1.5764 2.8243 1.3981 1.2599

10370 CITED2 9.06894432E-12 2.39116523E-10 -3.6783 1.3197 2.7504 1.9547 1.8374 4.1957 4.3184558 AXL AXL receptor tyrosine kinase 0.00681171281 0.015434476259 -3.6791 0.1729 0.6812 0.1922 0.2666 0.2472 0.2531671 BPI bactericidal/permeability-increasing protein 0.01942528116 0.038471573535 -3.6796 0.3562 0.2773 0.4014 0.2801 0.1194 0.359626137 ZBTB20 zinc finger and BTB domain containing 20 8.18614307E-11 1.40184823E-09 -3.6820 0.7307 0.7266 0.5817 0.7861 1.2169 0.8581100131117 ZBTB20-AS1 ZBTB20 antisense RNA 1 0.00653788445 0.014882002731 -3.6831 0.0814 0.0608 0.1305 0.6115 0.1803 0.146964581 CLEC7A C-type lectin domain family 7, member A 0.0140552881 0.029081443124 -3.6843 0.3223 1.0091 0.3106 0.3990 0.2963 0.17055800 PTPRO protein tyrosine phosphatase, receptor type, O 0.00117626776 0.00322085487 -3.6849 1.6253 1.4576 1.1210 1.2359 0.9137 0.6075147685 C19orf18 chromosome 19 open reading frame 18 0.00831622772 0.018380804754 -3.6860 0.1032 0.0039 0.2531 0.5197 0.0314 0.489779827 CLMP adipocyte-specific adhesion molecule 0.01047179107 0.022489488306 -3.6873 1.2950 1.0181 1.0545 1.1744 1.0044 0.6316400360 C15orf54 FLJ39531 protein 0.00812675728 0.018029639279 -3.6888 0.5176 0.6283 0.5927 0.3955 0.5096 0.3703283089 WDR11-AS1 hypothetical protein LOC283089 0.01377018083 0.028546263238 -3.6897 0.3321 0.3321 0.3321 0.3970 0.3970 0.397085462 FHDC1 FH2 domain containing 1 0.00872228979 0.019167008909 -3.6907 0.0781 0.2363 0.0589 0.2197 0.4734 0.241479628 SH3TC2 SH3 domain and tetratricopeptide repeats 2 0.01826649404 0.036477090605 -3.6925 0.1300 0.0341 0.2114 0.2532 0.0178 0.16849124 PDLIM1 PDZ and LIM domain 1 0.00011735072 0.00039737441 -3.6967 0.3909 2.4952 1.3569 0.3052 1.0089 0.875455064 SPATA6L spermatogenesis associated 6-like 1.51650837E-05 6.12638535E-05 -3.6973 2.8892 1.1898 1.4537 1.6713 0.7559 0.7856114792 KLHL32 kelch-like family member 32 5.64606487E-06 2.503615E-05 -3.6977 0.8545 1.0031 1.0813 0.8100 0.8841 0.99917803 PTP4A1 protein tyrosine phosphatase type IVA, member 1 6.04403674E-12 1.77177105E-10 -3.7092 0.6775 0.7300 0.8121 0.6258 0.6956 0.875423086 EXPH5 exophilin 5 3.47618559E-07 2.02025646E-06 -3.7096 0.9813 1.1030 0.9292 0.9589 1.2061 0.9386142913 CFL1P1 cofilin pseudogene 1 0.00429076575 0.010272650906 -3.7105 1.4790 0.5816 4.9476 1.0206 0.6415 1.3803595135 PGM5P2 phosphoglucomutase 5 pseudogene 2 5.0668832E-05 0.000184610349 -3.7111 0.7986 0.7971 0.9300 0.3188 1.5000 0.92959060 PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00028427604 0.000887003373 -3.7130 0.6165 0.6321 1.0795 0.6628 0.5700 0.83235782 PTPN12 protein tyrosine phosphatase, non-receptor type 12 3.53869907E-08 2.61460208E-07 -3.7174 0.7267 1.0434 0.7802 0.7620 1.0841 0.9662123036 TC2N tandem C2 domains, nuclear 6.31887365E-10 7.9352893E-09 -3.7207 2.2500 2.0459 2.4427 1.8799 1.3294 1.836251284 TLR7 toll-like receptor 7 0.01128180625 0.023995013837 -3.7213 0.5350 0.4000 0.4078 0.6378 0.3497 0.2974125336 LOXHD1 lipoxygenase homology domains 1 0.01219541816 0.025684034191 -3.7218 0.0478 0.0278 0.1773 0.2627 0.0882 0.1809112399 EGLN3 egl-9 family hypoxia-inducible factor 3 0.00528128678 0.012341689746 -3.7224 1.1396 1.7725 1.2495 0.7190 0.8486 1.0033777 CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 0.0249034101 0.047710568019 -3.7224 0.0946 0.2847 0.3253 0.2686 0.3290 0.26524603 MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 2.87975566E-07 1.70618986E-06 -3.7245 2.0391 3.0385 1.8934 2.0610 2.7104 2.88826144 RPL21 ribosomal protein L21 3.53449028E-15 8.72732518E-13 -3.7287 3.8594 3.4031 1.9161 4.0113 4.9740 3.00799465 AKAP7 A kinase (PRKA) anchor protein 7 1.39397889E-07 8.91521955E-07 -3.7305 2.1071 1.6464 1.1589 1.4393 1.1639 0.84122494 NR5A2 nuclear receptor subfamily 5, group A, member 2 0.01108713408 0.023630481035 -3.7307 0.8575 0.9428 0.6655 0.5981 0.3637 0.4031

4613 MYCN 0.00863721606 0.019000627475 -3.7353 2.0598 2.7440 0.9567 1.4041 1.6966 0.9064

solute carrier family 13 (sodium-dependent citrate transporter), member 5

solute carrier family 24 (sodium/potassium/calcium exchanger), member 4

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog

2162 F13A1 coagulation factor XIII, A1 polypeptide 7.60834946E-05 0.000268429738 -3.7403 0.1226 0.3227 0.1281 0.4631 0.0870 0.1169283897 C16orf54 chromosome 16 open reading frame 54 1.94102378E-09 2.06921741E-08 -3.7406 2.0829 1.6388 2.9488 2.1995 1.9414 2.391555742 PARVA parvin, alpha 0.0216771073 0.042312157313 -3.7411 0.4826 0.9185 0.5160 0.6259 0.4937 0.391580012 PHC3 polyhomeotic homolog 3 (Drosophila) 4.01796316E-15 9.53457441E-13 -3.7416 1.7033 1.9584 2.4335 1.9820 3.2396 3.161064168 NECAB1 N-terminal EF-hand calcium binding protein 1 6.51053304E-07 3.53733154E-06 -3.7422 0.1417 0.8514 0.0597 0.1420 0.2105 0.1225159686 CCDC147 chromosome 10 open reading frame 80 0.0067649411 0.015338007662 -3.7439 1.7178 0.9195 1.6250 0.8781 0.7064 1.164293979 CPA5 carboxypeptidase A5 0.00034569414 0.001059463819 -3.7470 0.0443 0.0979 0.1385 0.1850 0.0078 0.205329958 DMGDH dimethylglycine dehydrogenase 0.00725801343 0.016288187352 -3.7475 0.0576 0.0824 0.2183 0.4721 0.2498 0.1692126147 NTN5 netrin 5 0.00018461154 0.000597877018 -3.7491 0.0259 0.2781 0.1566 0.0244 0.0237 0.0973140462 ASB9 ankyrin repeat and SOCS box-containing 9 0.00765278513 0.017083896134 -3.7526 1.5315 0.6963 0.8587 0.8437 0.2140 0.37861200 TPP1 tripeptidyl peptidase I 1.88399545E-09 2.02139547E-08 -3.7544 2.4394 2.4656 1.8931 1.7706 2.4520 1.522023493 HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.01806513598 0.03613027195 -3.7546 2.4868 3.5938 2.4651 2.5035 2.4218 1.880294241 TP53INP1 tumor protein p53 inducible nuclear protein 1 2.17710901E-08 1.71047436E-07 -3.7552 1.1634 2.4172 2.0283 0.7817 1.7113 2.18496335 SCN9A sodium channel, voltage-gated, type IX, alpha subunit 0.01277216456 0.026741490882 -3.7585 0.4977 0.7267 0.6240 0.3004 0.4510 0.28977058 THBS2 thrombospondin 2 0.00400807287 0.009671884247 -3.7599 0.4927 0.6310 0.4258 0.3545 0.2482 0.306056158 TEX12 testis expressed 12 0.00774557788 0.01727416075 -3.7603 0.1041 0.0413 0.1617 0.2133 0.0108 0.1614121512 FGD4 FYVE, RhoGEF and PH domain containing 4 0.00140953655 0.003787737058 -3.7607 0.3109 0.3912 0.3738 0.2867 0.1987 0.300164776 C11orf1 chromosome 11 open reading frame 1 7.75537813E-14 6.74791758E-12 -3.7615 0.4787 0.8740 0.7237 0.4288 0.6445 0.390627145 FILIP1 filamin A interacting protein 1 0.0150439242 0.030840635367 -3.7634 0.0562 0.0755 0.1315 0.2023 0.1049 0.164127151 CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 0.00173447922 0.00456202739 -3.7663 0.4570 0.6238 0.2889 0.4601 0.3949 0.27665806 PTX3 pentraxin 3, long 0.01319749954 0.027515371013 -3.7668 0.5299 0.2690 0.8503 0.8790 0.0921 0.532451365 PLA1A phospholipase A1 member A 0.01910999038 0.03794173032 -3.7669 0.0905 0.3285 0.6038 0.2774 0.1842 0.17284008 LMO7 LIM domain 7 2.44724044E-09 2.52347502E-08 -3.7682 1.6013 1.6560 1.0994 1.3893 1.3814 0.929351348 KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.01556772483 0.03176831227 -3.7700 0.1149 0.2466 0.1594 0.2035 0.1495 0.20027480 WNT10B wingless-type MMTV integration site family, member 10B 0.00016745718 0.00054726841 -3.7704 1.0031 0.8522 0.9938 0.5006 0.4637 0.5218948 CD36 CD36 molecule (thrombospondin receptor) 0.00049833584 0.001472443793 -3.7719 0.0858 0.0825 0.0820 0.2586 0.0733 0.0974284900 TTC28-AS1 KIAA1648 protein 9.8538015E-12 2.56831523E-10 -3.7719 0.2675 0.1919 0.1962 0.2435 0.2074 0.29497552 ZNF711 zinc finger protein 711 1.64280092E-06 8.18344415E-06 -3.7729 1.8978 0.6198 0.5657 1.8718 0.5106 0.83756139 RPL17 ribosomal protein L17 9.07443354E-14 7.40214508E-12 -3.7742 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970338799 LOC338799 uncharacterized LOC338799 1.01984895E-07 6.72489355E-07 -3.7821 2.8827 2.5596 1.9002 3.2117 3.1274 2.93119976 CLEC2B C-type lectin domain family 2, member B 2.32414402E-07 1.4089834E-06 -3.7841 4.3634 4.3057 1.2202 4.6294 4.3833 1.47433606 IL18 interleukin 18 (interferon-gamma-inducing factor) 0.00505523791 0.011887941713 -3.7865 0.3209 0.0946 0.2770 0.4012 0.0687 0.1582285440 CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 4.2000692E-09 4.05193582E-08 -3.7894 3.2526 0.3239 1.6445 3.3756 1.2883 0.945856911 MAP3K7CL MAP3K7 C-terminal like 3.5215119E-06 1.63064028E-05 -3.7939 0.7181 0.6948 0.8225 0.7410 0.5526 0.6412100272147 CMC4 C-x(9)-C motif containing 4 homolog (S. cerevisiae) 2.21385469E-09 2.3101972E-08 -3.7973 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970692212 SNORD99 small nucleolar RNA, C/D box 99 0.01795653353 0.035948480401 -3.7984 0.3596 0.5842 0.5091 0.2466 0.3299 0.2374151556 GPR155 G protein-coupled receptor 155 1.97126371E-09 2.09290706E-08 -3.7989 1.7123 1.8743 1.6632 2.2243 1.9872 2.633650840 TAS2R14 taste receptor, type 2, member 14 0.00827414382 0.018303287641 -3.8000 0.1237 0.1295 0.0858 0.2324 0.1641 0.06166235 RPS29 ribosomal protein S29 2.92973461E-13 1.80242797E-11 -3.8008 1.5449 2.8611 1.3899 2.3637 4.1806 2.891150856 CLEC4A C-type lectin domain family 4, member A 0.00286210128 0.007149188595 -3.8043 0.3440 0.3063 0.2485 0.3204 0.3934 0.31921285 COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.02473685152 0.047438261026 -3.8050 0.2197 0.1788 0.2315 0.3150 0.2201 0.37616571 SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.79080325E-12 6.77464946E-11 -3.8071 0.7470 1.4203 0.6937 0.4261 2.2474 0.58021592 CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.0244726576 0.047025386444 -3.8080 0.5921 0.6465 1.4372 0.3420 0.5818 1.2316406934 MIR142 microRNA 142 0.00851430473 0.018761863968 -3.8082 1.6956 0.9815 1.8787 2.5923 3.3558 4.9307201895 SMIM14 chromosome 4 open reading frame 34 9.44477215E-07 4.94483888E-06 -3.8122 1.4462 0.9267 1.5092 1.2546 0.8438 1.7536728855 LINC00623 long intergenic non-protein coding RNA 623 2.84122597E-10 4.06219725E-09 -3.8145 0.9687 1.1039 0.7942 1.9965 2.6439 2.182727031 NPHP3 nephronophthisis 3 (adolescent) 5.67850156E-10 7.25577486E-09 -3.8183 0.4094 1.5618 0.9371 0.6015 1.6523 0.3790284422 C19orf77 similar to HSPC323 0.00321318813 0.007931825664 -3.8227 0.1543 0.2153 0.5789 0.1679 0.1358 0.3115144363 LYRM5 LYR motif containing 5 4.02053713E-11 7.87563963E-10 -3.8230 0.6019 1.2117 0.2744 0.8308 3.3850 0.2827253018 HCG27 HLA complex group 27 6.30920406E-05 0.00022586555 -3.8234 0.6274 0.9394 0.5057 0.7761 1.0418 0.76488825 LIN7A lin-7 homolog A (C. elegans) 0.01765589383 0.035443692817 -3.8247 0.1676 0.0856 0.3044 0.2606 0.0992 0.2760729085 FAM198A family with sequence similarity 198, member A 0.02422904025 0.046630821933 -3.8263 0.9326 2.3628 0.9077 0.6611 0.9775 0.6223342908 ZNF404 zinc finger protein 404 9.64553773E-06 4.06652666E-05 -3.8270 0.0497 0.0044 0.1638 0.7081 0.1540 0.1736643201 LOC643201 hypothetical protein LOC643201 0.02512291499 0.048050416632 -3.8314 1.0976 1.6531 1.1082 0.7980 1.2581 0.9559123876 ACSM2A hypothetical protein LOC123876 0.0219125739 0.042689684427 -3.8317 0.0379 0.0352 0.1303 0.2379 0.0358 0.1558100188949 LINC00426 long intergenic non-protein coding RNA 426 8.54867586E-06 3.64615792E-05 -3.8348 1.7262 1.3038 2.1606 1.0401 0.7193 1.0516283194 LOC283194 hypothetical protein LOC283194 0.00889278151 0.019492430871 -3.8354 1.6457 0.9759 1.4587 1.1588 0.9764 1.09741953 MEGF6 multiple EGF-like-domains 6 5.49261255E-06 2.44246815E-05 -3.8369 1.1780 1.4786 1.3223 0.7495 1.0324 1.19836565 SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 6.92263531E-06 3.01095911E-05 -3.8382 0.1735 0.0583 0.1628 0.4405 0.0148 0.1280

3363 HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 0.01807556107 0.03614716558 -3.8400 1.6159 1.1923 1.6256 1.2166 1.0134 1.2631653505 PPIAL4B peptidylprolyl isomerase A (cyclophilin A)-like 4B 0.0135777093 0.028217914499 -3.8481 1.8239 0.9433 0.5277 2.0409 0.6406 0.356790273 CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 9.41767094E-09 8.10549615E-08 -3.8484 2.5355 2.1546 1.9510 2.4062 2.2992 1.5609619373 MBOAT4 membrane bound O-acyltransferase domain containing 4 0.00010878035 0.000370896535 -3.8533 0.1643 0.1586 0.2997 0.2316 0.2883 0.4688

100306975 NDUFAF4P1 0.00014779944 0.000488794827 -3.8558 1.0314 1.8520 0.7913 0.4481 0.5052 0.60844033 LRMP lymphoid-restricted membrane protein 1.20353449E-07 7.80929765E-07 -3.8584 3.0177 3.1934 2.8901 2.5269 2.5847 2.8496131450 CD200R1 CD200 receptor 1 5.16493558E-06 2.30855438E-05 -3.8587 4.9838 2.8572 2.2203 3.9653 2.0520 1.247910158 PDZK1IP1 PDZK1 interacting protein 1 5.72513817E-05 0.000206493732 -3.8593 0.0568 0.0128 0.1946 0.0327 0.0206 0.177922890 ZBTB1 zinc finger and BTB domain containing 1 2.93357096E-16 2.05875022E-13 -3.8593 0.3321 0.3321 0.3321 0.3970 0.3970 0.397083873 GPR61 G protein-coupled receptor 61 0.0216147472 0.042209576054 -3.8594 0.0657 0.0530 0.0914 0.0828 0.1167 0.1441100131289 LOC100131289 uncharacterized LOC100131289 7.98608903E-06 3.43022611E-05 -3.8601 0.1773 0.1517 0.6342 0.4020 0.2071 0.3126541466 CT45A1 cancer/testis antigen CT45-1 0.02040497801 0.040138891357 -3.8631 0.0068 0.0112 0.1679 0.0219 0.0327 0.222710863 ADAM28 ADAM metallopeptidase domain 28 0.01516152536 0.0310538495 -3.8687 0.1615 0.0825 0.1772 0.1407 0.1243 0.1822

728358 DEFA1B 0.00053972205 0.001583161678 -3.8718 0.0492 0.0115 0.1938 0.1537 0.0125 0.1492828 CAPS calcyphosine 2.62921571E-07 1.57356795E-06 -3.8748 0.0226 0.0367 0.2325 0.1552 0.0121 0.079190423 ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 2.83148336E-07 1.68140604E-06 -3.8759 0.1528 0.0918 0.1378 0.4038 0.0262 0.3140146861 SLC35G3 acyl-malonyl condensing enzyme 1 0.0019394873 0.005043163781 -3.8761 0.2002 0.3254 0.3542 0.1463 0.2260 0.36716532 SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.00433906846 0.010376057953 -3.8789 0.8930 0.4116 0.7220 0.5936 0.3001 0.465979642 ARSJ arylsulfatase family, member J 0.02119893085 0.041520727242 -3.8814 1.2056 2.0794 1.0367 0.8868 1.4986 0.8387200232 FAM209A family with sequence similarity 209, member A 0.00081756084 0.002312814926 -3.8847 0.3321 0.3321 0.3321 0.3970 0.3970 0.397055567 DNAH3 dynein, axonemal, heavy chain 3 0.02491018054 0.047710568019 -3.8852 0.2824 0.4651 0.6005 0.2926 0.3389 0.5384283070 LOC283070 hypothetical protein LOC283070 7.01108423E-09 6.26744281E-08 -3.8876 0.0083 0.0176 0.2057 1.0029 0.0169 0.21583382 ICA1 islet cell autoantigen 1, 69kDa 0.00035437789 0.001081943324 -3.8879 0.4351 0.8776 0.6734 0.3438 0.4916 0.683810581 IFITM2 interferon induced transmembrane protein 2 1.63841267E-10 2.50972934E-09 -3.8902 1.8015 1.6296 2.0086 1.3852 1.7914 2.4562493860 CCDC73 coiled-coil domain containing 73 1.12406387E-07 7.35370391E-07 -3.8958 0.1383 0.0963 0.1831 0.1623 0.0188 0.2487139105 BEND2 chromosome X open reading frame 20 0.01170895564 0.024805337677 -3.8964 0.0807 0.1411 0.2852 0.1200 0.0113 0.2880221037 JMJD1C jumonji domain containing 1C 3.59092044E-14 4.16720895E-12 -3.8975 0.7807 1.0556 0.5801 0.9701 1.3483 0.55727320 UBE2B ubiquitin-conjugating enzyme E2B 6.61608758E-14 6.04445761E-12 -3.9012 1.4242 2.6803 4.3164 3.2596 4.4978 5.665384709 MGARP mitochondria-localized glutamic acid-rich protein 0.01092385402 0.023331418609 -3.9013 1.2449 2.0729 1.4760 0.7029 0.9413 1.3036100131089 SRP14-AS1 SRP14 antisense RNA1 (head to head) 1.93229108E-09 2.06159773E-08 -3.9050 1.4603 0.9821 6.5659 0.8095 0.6483 2.3508100506627 DCDC5 doublecortin domain containing 5 0.02632642923 0.04998820689 -3.9107 0.0452 0.0471 0.0795 0.1994 0.1958 0.147825893 TRIM58 tripartite motif containing 58 0.00027026402 0.000848207532 -3.9118 0.4842 0.4905 0.6050 0.6484 0.2684 0.50876586 SLIT3 slit homolog 3 (Drosophila) 0.00769818815 0.017172664365 -3.9143 0.1173 0.2175 0.2726 0.1872 0.0819 0.227757228 SMAGP small cell adhesion glycoprotein 7.58466336E-09 6.69178991E-08 -3.9144 1.4753 2.3070 1.0627 1.1969 1.1905 0.893784084 RAB6C RAB6C, member RAS oncogene family 1.20929804E-09 1.38274679E-08 -3.9154 0.1445 0.6634 0.3202 0.1257 0.0963 0.134890139 TSPAN18 tetraspanin 18 9.34883861E-08 6.23665495E-07 -3.9171 0.0736 0.0610 0.1936 0.1017 0.2086 0.2156441502 RPS26P11 ribosomal protein S26 pseudogene 11 3.12273986E-09 3.12308171E-08 -3.9214 0.0697 0.1007 0.0920 0.1876 0.0773 0.22624306 NR3C2 nuclear receptor subfamily 3, group C, member 2 9.16645486E-09 7.90768148E-08 -3.9221 2.6620 2.9025 1.5714 2.7805 3.3815 2.666784106 PRAM1 PML-RARA regulated adaptor molecule 1 0.00056128168 0.001639606546 -3.9250 0.6801 0.7129 0.4808 0.5706 0.6689 0.3305647121 EMBP1 embigin pseudogene 1 6.98368151E-13 3.34364607E-11 -3.9259 1.2518 1.3214 1.1639 1.0525 1.0865 1.3886694 BTG1 B-cell translocation gene 1, anti-proliferative 7.13464247E-11 1.25834158E-09 -3.9276 1.1691 2.4782 1.3101 1.7074 4.4307 3.137556163 RNF17 ring finger protein 17 0.00176970023 0.004641303666 -3.9323 0.0627 0.0626 0.1717 0.1459 0.0648 0.210810123 ARL4C ADP-ribosylation factor-like 4C 5.34921086E-09 4.99186828E-08 -3.9342 0.7585 2.7840 1.2369 1.3111 3.9076 2.6410341350 OVCH1 ovochymase 1 0.02456401853 0.047166219693 -3.9368 0.1213 0.0038 0.1252 0.1410 0.0168 0.228084689 MS4A14 membrane-spanning 4-domains, subfamily A, member 14 0.004292075 0.010274439193 -3.9421 0.2290 0.2496 0.2892 0.3365 0.2114 0.26592053 EPHX2 epoxide hydrolase 2, cytoplasmic 5.28235404E-07 2.92770981E-06 -3.9422 0.8679 1.6048 0.8653 0.8182 1.2651 0.7603127254 C1orf173 chromosome 1 open reading frame 173 0.02615284146 0.049730952141 -3.9454 0.1198 0.0940 0.4517 0.1930 0.0729 0.1930286554 BCORP1 BCL6 co-repressor-like 2 5.86870619E-08 4.1101188E-07 -3.9458 1.1952 3.3985 1.2255 0.8900 4.3933 1.5193378948 RBMY1B RNA binding motif protein, Y-linked, family 1, member B 0.02116410731 0.041465855543 -3.9518 0.0334 0.2407 0.3181 0.2025 0.0720 0.272379830 ZMYM1 zinc finger, MYM-type 1 3.28204329E-08 2.44474093E-07 -3.9548 1.9672 1.5365 2.3315 1.8276 1.7911 2.302155 ACPP acid phosphatase, prostate 0.0225243445 0.043704451819 -3.9551 0.3947 0.2350 0.2893 0.2710 0.0984 0.0900137872 ADHFE1 alcohol dehydrogenase, iron containing, 1 0.00022167353 0.000706016852 -3.9614 1.9877 2.0568 2.0121 1.5331 1.6217 1.90642282 FKBP1AP1 FK506 binding protein 1A, 12kDa pseudogene 1 2.03726544E-07 1.25590129E-06 -3.9679 0.2137 1.0091 0.1894 0.5133 0.2345 0.280760675 PROK2 prokineticin 2 0.00176007008 0.004618698901 -3.9687 0.6550 1.7282 1.0793 0.3518 1.1612 0.58261178 CLC Charcot-Leyden crystal galectin 0.02244947202 0.043586946425 -3.9696 0.3395 0.1895 0.6803 0.2080 0.0702 0.4491

100288527 REXO1L2P 0.0250162058 0.047898576176 -3.9704 0.0257 0.0439 0.1487 0.2966 0.3071 0.232379668 PARP8 poly (ADP-ribose) polymerase family, member 8 4.38915837E-11 8.45977866E-10 -3.9704 1.7884 1.1764 1.2834 1.8659 2.0549 1.9085222255 ATXN7L1 ataxin 7-like 1 4.67882735E-14 4.85747348E-12 -3.9706 1.3912 0.5932 1.1535 1.5318 0.5434 0.6034376940 ZC3H6 zinc finger CCCH-type containing 6 1.77092729E-11 4.12493167E-10 -3.9722 0.9722 1.4520 1.2094 1.0542 2.2764 1.8096144571 A2M-AS1 hypothetical protein LOC144571 0.00132047099 0.003574652654 -3.9781 1.7414 0.2667 0.3007 1.5062 0.3957 0.038380177 MYCT1 myc target 1 0.0042012551 0.010086103422 -3.9783 0.0860 0.0040 0.0855 0.2157 0.0640 0.298464805 P2RY12 purinergic receptor P2Y, G-protein coupled, 12 0.00066861657 0.001919397014 -3.9799 0.4301 0.2218 0.1991 0.3980 0.1472 0.14116339 SCNN1D sodium channel, non-voltage-gated 1, delta subunit 1.19521746E-07 7.76899511E-07 -3.9855 0.0888 0.0547 0.2505 0.2814 0.0869 0.1946401024 FSIP2 fibrous sheath interacting protein 2 0.0045569069 0.010841640991 -3.9857 0.0891 0.1134 0.2748 0.3195 0.0518 0.168651744 CD244 CD244 molecule, natural killer cell receptor 2B4 7.49596081E-05 0.000264617844 -3.9870 0.2946 0.8786 1.4072 0.2407 0.2171 0.53174189 DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 4.05341937E-11 7.90950479E-10 -3.9876 0.6073 16.4933 2.5242 0.4414 10.7821 4.39822791 GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00010500355 0.000359427655 -3.9878 0.5976 0.6902 0.8952 0.5514 0.3777 0.6162353189 SLCO4C1 solute carrier organic anion transporter family, member 4C1 1.46140925E-05 5.92447166E-05 -3.9881 1.8107 1.1627 1.3745 1.1472 0.6745 1.10533887 KRT81 keratin 81 0.02151489735 0.042044941652 -3.9948 0.2245 0.2330 0.4642 0.1997 0.1071 0.35809241 NOG noggin 0.00062445061 0.001806003389 -3.9965 1.6831 3.1210 1.7095 2.4656 2.4294 2.4023546 ATRX alpha thalassemia/mental retardation syndrome X-linked 1.03495145E-15 4.39782159E-13 -3.9975 3.9808 1.6658 1.7948 4.9318 2.0861 2.2400401494 PTPLAD2 protein tyrosine phosphatase-like A domain containing 2 1.73193161E-10 2.62403436E-09 -3.9976 2.8706 4.0709 1.5880 2.2300 2.4655 1.3978402415 XKRX XK, Kell blood group complex subunit-related, X-linked 6.01600376E-06 2.64686782E-05 -3.9993 1.6587 1.6144 1.9772 1.9220 0.9118 1.45484311 MME membrane metallo-endopeptidase 0.00951078312 0.020703005622 -4.0042 0.2329 0.6288 0.4099 0.2966 0.3026 0.32425577 PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00040885944 0.001232582016 -4.0076 1.5418 1.1427 1.1762 1.0537 0.6662 0.94626932 TCF7 transcription factor 7 (T-cell specific, HMG-box) 3.57181886E-08 2.63694037E-07 -4.0101 1.0284 0.8163 1.2172 1.2998 0.8480 1.027856171 DNAH7 dynein, axonemal, heavy chain 7 0.00392930585 0.00949309487 -4.0135 0.5710 0.4558 0.5683 0.6418 0.4416 0.522690288 EFCAB12 EF-hand calcium binding domain 12 8.7181268E-05 0.000303713275 -4.0143 1.1108 2.8478 1.1313 0.6629 2.6160 0.56997273 TTN titin 8.85105689E-08 5.94582763E-07 -4.0144 0.0997 0.0812 0.2105 0.2158 0.0566 0.1714100505576 LINC00672 long intergenic non-protein coding RNA 672 1.35207096E-06 6.86060554E-06 -4.0151 0.8489 0.8204 0.9381 0.5827 0.6555 0.45008674 VAMP4 vesicle-associated membrane protein 4 7.85644231E-12 2.16520232E-10 -4.0163 2.0261 1.2525 1.0817 1.9139 1.5949 1.8339

NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 pseudogene 1

similar to Neutrophil defensin 1 precursor (HNP-1) (HP-1) (HP1) (Defensin, alpha 1)

REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 2 (pseudogene)

284233 CYP4F35P hypothetical protein LOC284233 6.75407808E-05 0.000240425706 -4.0173 0.0881 0.1575 0.1519 0.0895 0.0114 0.2296163115 ZNF781 zinc finger protein 781 2.49876069E-05 9.64252487E-05 -4.0177 2.4603 1.6229 1.4820 2.5430 2.2177 1.343451742 ARID4B AT rich interactive domain 4B (RBP1-like) 5.74766617E-15 1.23554537E-12 -4.0186 0.3238 0.2953 0.1947 0.3198 0.3763 0.2732158399 ZNF483 zinc finger protein 483 3.35286629E-10 4.65528668E-09 -4.0192 3.1408 1.5489 1.5880 3.4389 2.9478 1.675380318 GKAP1 G kinase anchoring protein 1 1.44179291E-08 1.18348787E-07 -4.0194 0.7521 1.1303 0.8146 0.7397 0.9113 0.897683439 TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 2.98538851E-06 1.40084794E-05 -4.0198 1.3615 1.2084 1.2987 1.6215 0.6029 0.87071517 CTSLP2 cathepsin L pseudogene 2 0.02522494693 0.048212367196 -4.0318 0.0525 0.0375 0.1810 0.1000 0.0747 0.1841255239 ANKK1 ankyrin repeat and kinase domain containing 1 0.01309596888 0.027338003366 -4.0325 0.1458 0.3636 0.3416 0.1722 0.5738 0.32554601 MXI1 MAX interactor 1, dimerization protein 2.29903664E-13 1.52202889E-11 -4.0359 1.8865 2.1270 1.8793 1.6176 2.2191 2.370580312 TET1 tet methylcytosine dioxygenase 1 6.17954974E-09 5.63718087E-08 -4.0366 0.6794 0.7823 0.7608 0.6162 0.4801 0.664610516 FBLN5 fibulin 5 3.5644301E-07 2.06628384E-06 -4.0380 1.3920 1.1667 1.1064 0.9578 0.6991 0.72103577 CXCR1 chemokine (C-X-C motif) receptor 1 0.01731723172 0.034832723255 -4.0392 1.7026 0.8693 0.6537 0.9942 0.2461 0.37171602 DACH1 dachshund family transcription factor 1 0.00059859294 0.001737764578 -4.0397 1.2955 1.8318 1.7575 1.3646 1.7519 1.1422284217 LAMA1 laminin, alpha 1 0.0127519108 0.026708266186 -4.0489 0.1499 0.3492 0.3252 0.2680 0.0876 0.153993978 CLEC6A C-type lectin domain family 6, member A 0.02550804685 0.048671995825 -4.0504 0.1045 0.1946 0.1093 0.2315 0.0557 0.1009375033 PEAR1 platelet endothelial aggregation receptor 1 0.00110224185 0.003035442822 -4.0512 0.4912 0.2516 0.6042 0.5390 0.3319 0.4311388011 C14orf64 chromosome 14 open reading frame 64 5.40753358E-10 6.93865544E-09 -4.0514 2.8861 1.9152 3.1852 2.6182 1.9697 3.2715144321 GLIPR1L2 GLI pathogenesis-related 1 like 2 0.00466433175 0.011066961408 -4.0516 4.3798 1.1677 1.1698 2.2459 0.8024 0.3645126969 SLC44A3 solute carrier family 44, member 3 0.01494619007 0.030667802925 -4.0522 0.1449 0.1965 0.2990 0.3697 0.2473 0.293379469 DLEU2L deleted in lymphocytic leukemia 2-like 0.00296242663 0.007379612719 -4.0586 0.0477 0.1003 0.1741 0.1663 0.0653 0.1250157869 SBSPON somatomedin B and thrombospondin, type 1 domain containing 9.66642007E-05 0.000333128683 -4.0605 0.3355 0.1723 0.2289 0.1885 0.2595 0.2467100505746 ITGB2-AS1 ITGB2 antisense RNA 1 8.42715507E-08 5.69456278E-07 -4.0631 3.0676 1.2266 0.5690 5.6077 2.8422 0.8559220594 USP32P2 TL132 protein 3.56587051E-07 2.06646324E-06 -4.0635 0.1193 0.1436 0.1123 0.2038 0.0424 0.1848140 ADORA3 adenosine A3 receptor 0.00755894203 0.016901246801 -4.0644 0.6647 0.5742 0.4835 0.4879 0.2983 0.30507045 TGFBI transforming growth factor, beta-induced, 68kDa 0.00469733157 0.011133693411 -4.0693 0.2460 0.0848 0.1634 0.3580 0.0494 0.2147387778 SPDYC speedy/RINGO cell cycle regulator family member C 0.01518469173 0.031087359921 -4.0713 0.0871 0.1617 0.4838 0.0558 0.0522 0.2477727 C5 complement component 5 1.69602284E-09 1.8501331E-08 -4.0722 0.0564 0.0326 0.1047 0.2150 0.0132 0.2413729264 TP53TG3D TP53 target 3D 0.00262811987 0.006631819684 -4.0754 0.6884 0.3838 0.5300 1.1746 0.3614 0.6196

55251 PCMTD2 1.17283451E-12 4.85891104E-11 -4.0777 1.9678 1.7988 1.8986 1.4697 2.7952 1.8780285512 FAM13A-AS1 family with sequence similarity 13, member A1 opposite strand 3.37052742E-06 1.56668219E-05 -4.0810 0.0556 0.0885 0.1528 0.2481 0.1200 0.1695140597 TCEAL2 transcription elongation factor A (SII)-like 2 0.00483258599 0.011418726385 -4.0924 0.9600 1.1525 0.7469 0.4995 1.1990 0.45729717 SEC14L5 SEC14-like 5 (S. cerevisiae) 0.01359925863 0.028256271732 -4.0925 1.2264 1.3927 1.2313 0.9830 0.8631 0.93154168 MCF2 MCF.2 cell line derived transforming sequence 0.00502841469 0.011832478195 -4.0926 0.1420 0.1312 0.6607 0.2180 0.0954 0.4029627 BDNF brain-derived neurotrophic factor 0.02505405282 0.047956163775 -4.0961 0.4323 0.5996 0.5504 0.5723 0.3212 0.3636121793 TEX29 testis expressed 29 0.01461321586 0.03006560976 -4.1005 0.0831 0.0184 0.1106 0.1699 0.1387 0.24088850 KAT2B K(lysine) acetyltransferase 2B 9.54601216E-14 7.71790859E-12 -4.1017 2.3536 2.7435 1.6366 2.3807 3.4190 2.542725849 PARM1 prostate androgen-regulated mucin-like protein 1 0.008175432 0.018126622188 -4.1024 0.2965 1.2863 0.9387 0.5905 0.2018 0.5503441666 LOC441666 zinc finger protein 91 pseudogene 0.0085968606 0.01893236555 -4.1028 0.2385 0.8477 0.2445 0.2180 0.4095 0.5037647946 LINC00669 long intergenic non-protein coding RNA 669 0.02469990406 0.047387300189 -4.1031 0.2427 0.1566 0.3211 0.2897 0.2805 0.263310911 UTS2 urotensin 2 0.00425115664 0.010195187571 -4.1040 0.1993 0.2521 0.4169 0.2553 0.1380 0.402357639 CCDC146 KIAA1505 protein 1.10801619E-08 9.3556709E-08 -4.1046 0.4189 0.3543 0.7192 0.5828 0.5008 0.810291156 IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 0.01792067892 0.035892430696 -4.1067 0.0268 0.0467 0.3133 0.0785 0.0339 0.223227296 TP53TG5 TP53 target 5 0.00433068688 0.010358726353 -4.1069 0.0658 0.2180 0.2335 0.2053 0.1614 0.168823305 ACSL6 acyl-CoA synthetase long-chain family member 6 1.4583116E-10 2.26199233E-09 -4.1103 0.6449 0.5176 0.4587 0.5290 0.4154 0.3995128344 PIFO primary cilia formation 0.00320675575 0.00791808664 -4.1128 1.3817 2.2322 1.4817 1.2353 1.8938 1.664154094 C21orf15 chromosome 21 open reading frame 15 0.00143960164 0.003862046859 -4.1160 0.1108 0.1272 0.1768 0.6317 0.1560 0.1938389816 LRRC26 leucine rich repeat containing 26 0.01960308503 0.038756499638 -4.1160 0.2116 0.4160 1.3449 0.0763 0.6904 0.8016100750325 RCAN3AS RCAN3 antisense 3.03692575E-06 1.42320357E-05 -4.1223 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970148345 C1orf127 chromosome 1 open reading frame 127 0.02154312248 0.042095597684 -4.1238 0.2241 0.2519 0.3738 0.2055 0.1205 0.311125975 EGFL6 EGF-like-domain, multiple 6 0.01604968325 0.032591666179 -4.1283 0.4912 0.6184 0.8367 0.2350 0.4751 0.75068470 SORBS2 sorbin and SH3 domain containing 2 0.00996899057 0.021573566578 -4.1298 0.0593 0.0703 0.0982 0.1669 0.0880 0.160180127 CCDC176 chromosome 14 open reading frame 45 5.4026397E-08 3.81588838E-07 -4.1389 0.2136 0.1814 0.9631 0.5504 2.7338 0.1574158830 CXorf65 similar to Ab2-183 4.87234972E-09 4.62000904E-08 -4.1423 1.4719 0.8892 1.8184 0.6006 0.4468 0.92315789 PTPRD protein tyrosine phosphatase, receptor type, D 0.00514038513 0.012057139541 -4.1437 0.1250 0.3739 0.4566 0.3521 0.1080 0.3446162461 TMEM92 transmembrane protein 92 0.00353595792 0.008635261044 -4.1469 0.1546 0.2244 0.3850 0.2140 0.0629 0.4058220164 DOK6 docking protein 6 9.74186665E-06 4.10240579E-05 -4.1490 0.3612 0.3503 0.7869 0.3658 0.4652 0.6633340286 FAM183B hypothetical protein LOC340286 0.0007730439 0.002197084802 -4.1503 0.0468 0.1036 0.1852 0.3736 0.0522 0.09426844 VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 1.64050387E-14 2.43701519E-12 -4.1528 1.4097 3.3052 1.7221 1.0984 3.6243 1.8834225 ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 6.8938396E-09 6.19293201E-08 -4.1562 3.4599 3.5446 2.2877 3.2580 3.1414 2.519624150 TP53TG3 TP53 target 3 0.02327971976 0.0449790673 -4.1596 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702299 FOXI1 forkhead box I1 0.02212241242 0.043029669971 -4.1617 0.1018 0.0827 0.2713 0.1142 0.0185 0.2518728640 FAM133CP family with sequence similarity 133, member A pseudogene 0.00012656588 0.000425738546 -4.1645 0.1079 0.0611 0.0547 0.2927 0.0532 0.055165217 PCDH15 protocadherin-related 15 0.01938759612 0.038405264136 -4.1647 0.0593 0.0356 0.0764 0.1363 0.0517 0.1921374407 DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 0.00628463719 0.014364885011 -4.1657 0.0276 0.0977 0.1526 0.1256 0.0117 0.1559441459 ANKRD18B ankyrin repeat domain 18B 0.01241212391 0.026087950785 -4.1758 1.2415 1.2916 1.4815 0.9847 0.8080 1.486979887 PLBD1 phospholipase B domain containing 1 0.00238223078 0.006067482699 -4.1768 0.2632 0.6694 1.0133 0.2199 0.6840 0.8482389766 C9orf153 chromosome 9 open reading frame 153 0.02166771825 0.042302868669 -4.1804 0.0737 0.0981 0.1992 0.2485 0.0395 0.203755607 PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.01102356892 0.023516947033 -4.1806 0.2780 0.3056 0.3459 0.4046 0.1916 0.3510729176 KATNBL1P6 katanin p80 subunit B-like 1 pseudogene 6 0.00040732898 0.001229184979 -4.1818 0.1454 0.2033 0.1806 0.1524 0.0484 0.1176285189 PLGLA plasminogen-like A1 0.00204789973 0.005300173351 -4.1832 0.0345 0.1820 0.1641 0.1628 0.0106 0.2569374 AREG amphiregulin 5.99555208E-06 2.63977657E-05 -4.1837 2.1702 1.9895 1.5849 2.3290 2.2015 1.685211082 ESM1 endothelial cell-specific molecule 1 0.00821852909 0.018204505218 -4.1846 1.0180 0.5714 0.4754 1.1603 0.3783 0.37493479 IGF1 insulin-like growth factor 1 (somatomedin C) 0.01036323283 0.02230814391 -4.1849 0.4548 0.8019 1.0304 0.4352 0.2444 0.54202917 GRM7 glutamate receptor, metabotropic 7 0.02281390403 0.04420995381 -4.1853 0.0579 0.0821 0.1822 0.1783 0.0440 0.141623285 KIAA1107 KIAA1107 2.99705678E-09 3.02219766E-08 -4.1865 0.0737 0.0380 0.0844 0.1636 0.0573 0.10893725 JUN jun proto-oncogene 1.70616924E-07 1.07057432E-06 -4.1902 1.5120 2.0731 1.6625 1.8343 2.3995 3.802684698 CAPS2 calcyphosine 2 3.95490127E-05 0.000147387224 -4.1916 0.6763 0.3534 0.3339 0.5203 0.3507 0.297155287 TMEM40 transmembrane protein 40 1.17305599E-06 6.02122355E-06 -4.1925 0.0999 0.0541 0.3098 0.1378 0.0255 0.1591148534 TMEM56 transmembrane protein 56 0.00011805468 0.000399536048 -4.1985 0.2356 0.0648 0.3882 0.3867 0.0846 0.24983434 IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.01943821863 0.03849302383 -4.2003 3.0718 2.1192 1.4434 2.7784 1.6755 0.787857561 ARRDC3 arrestin domain containing 3 2.59976392E-08 1.99340689E-07 -4.2011 2.1397 3.7576 1.6219 2.4621 5.3100 2.042963901 FAM111A family with sequence similarity 111, member A 9.20941916E-16 4.17311256E-13 -4.2016 2.2912 2.2973 2.0715 1.9106 1.9985 2.05362829 XCR1 chemokine (C motif) receptor 1 0.00936064328 0.02041257016 -4.2041 0.0604 0.0354 0.1549 0.1285 0.0385 0.4369114769 CARD16 caspase-1 dominant-negative inhibitor pseudo-ICE 5.81902327E-05 0.000209673029 -4.2082 0.3321 0.3321 0.3321 0.3970 0.3970 0.39708633 UNC5C unc-5 homolog C (C. elegans) 0.01795252755 0.035944398796 -4.2095 1.1928 2.7791 1.4889 1.0643 1.1073 0.9785165530 CLEC4F C-type lectin domain family 4, member F 0.01848070425 0.03687664389 -4.2119 0.1207 0.0427 0.4499 0.5571 0.1592 0.372157337 SENP7 SUMO1/sentrin specific peptidase 7 1.41302704E-10 2.20862533E-09 -4.2122 1.2451 1.4897 1.0966 1.4169 2.0738 1.516711037 STON1 stonin 1 0.00057375808 0.001672843091 -4.2126 3.0049 1.4138 1.0902 3.9022 0.2775 1.319764843 ISL2 ISL LIM homeobox 2 0.00661195629 0.015026575297 -4.2146 1.6266 0.8709 2.3017 0.8652 0.6675 1.86905175 PECAM1 platelet/endothelial cell adhesion molecule 1 3.97527204E-05 0.000147995458 -4.2163 0.1477 0.4459 0.2451 0.2618 0.1400 0.246364478 CSMD1 CUB and Sushi multiple domains 1 0.0224491246 0.043586946425 -4.2165 0.0653 0.0385 0.1420 0.1580 0.1804 0.21454133 MAP2 microtubule-associated protein 2 0.00135715353 0.003660748339 -4.2174 0.5856 0.4210 0.5644 0.5229 0.3171 0.3211124602 KIF19 kinesin family member 19 0.0042691035 0.010226148283 -4.2209 1.1262 1.0785 0.9938 0.4181 0.7870 0.6029223075 CCDC129 coiled-coil domain containing 129 0.02456152593 0.047166219693 -4.2247 0.0371 0.0146 0.1143 0.2410 0.0451 0.097084439 HHIPL1 HHIP-like 1 0.01166412967 0.024724707336 -4.2261 0.4546 0.2640 0.5721 0.0342 0.0668 0.52201600 DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.00203609387 0.005271111807 -4.2287 0.3812 0.4480 0.4042 0.4782 0.3457 0.3609100131096 TNRC6C-AS1 TNRC6C antisense RNA 1 9.02896992E-09 7.81512735E-08 -4.2339 0.1601 0.2366 0.3242 0.1602 0.2144 0.2251100132979 GOLGA8DP golgin A8 family, member D, pseudogene 0.00790845245 0.017596595619 -4.2353 0.0492 0.0344 0.3281 0.2736 0.0197 0.20402330 FMO5 flavin containing monooxygenase 5 0.00303922116 0.007553407096 -4.2376 1.7641 1.9249 1.6220 1.3661 2.0835 1.45526401 SELE selectin E 0.00493698926 0.011630823582 -4.2443 0.1455 0.0339 0.1511 0.1917 0.0468 0.219580063 ATF7IP2 activating transcription factor 7 interacting protein 2 3.6710143E-13 2.10421995E-11 -4.2446 0.7646 1.2359 0.6119 1.1528 1.3016 0.7802731223 LOC731223 uncharacterized LOC731223 0.01797165978 0.035974821151 -4.2458 2.2870 1.9386 1.8670 1.3244 1.5157 1.7244442454 UQCRBP1 ubiquinol-cytochrome c reductase binding protein pseudogene 1 3.76434255E-15 9.050272E-13 -4.2496 0.7309 0.7270 0.4345 0.8904 0.2665 0.2617171558 PTCRA pre T-cell antigen receptor alpha 0.00037281091 0.001132314 -4.2510 0.2561 0.0822 0.1569 0.1088 0.1264 0.166880726 KIAA1683 KIAA1683 1.2459912E-06 6.35875351E-06 -4.2538 0.4252 0.4152 0.5304 0.2460 0.6126 0.40762028 ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.00819054155 0.018156524074 -4.2539 0.0432 0.0523 0.2316 0.1114 0.0289 0.05165592 PRKG1 protein kinase, cGMP-dependent, type I 0.02412130957 0.046462636349 -4.2545 0.3593 0.3711 0.5844 0.3742 0.2107 0.474355714 TENM3 teneurin transmembrane protein 3 0.02023672246 0.039853700367 -4.2587 0.1326 0.2166 0.3666 0.2896 0.1593 0.2362

4157 MC1R 4.99245645E-09 4.71009864E-08 -4.2592 1.0622 1.7360 0.8612 0.4088 0.5780 0.330479442 LRRC2 leucine rich repeat containing 2 0.00125927734 0.003424544663 -4.2595 0.8811 1.7876 0.6241 0.8298 1.4476 0.4297728875 LOC728875 uncharacterized LOC728875 9.46133647E-11 1.58167923E-09 -4.2660 1.5669 1.7787 1.2719 1.7675 2.4026 1.6035283537 SLC46A3 solute carrier family 46, member 3 1.51117952E-09 1.67245743E-08 -4.2691 1.3020 1.2787 1.0793 1.1904 1.5283 1.2058284415 VSTM1 V-set and transmembrane domain containing 1 0.00124258577 0.003383685135 -4.2699 0.0616 0.1037 0.0806 0.1983 0.0341 0.25261299 COL9A3 collagen, type IX, alpha 3 0.0042828485 0.010255039669 -4.2702 0.1576 0.3972 0.3885 0.2677 0.3954 0.2266339965 CCDC158 hypothetical protein FLJ25770 0.02508215664 0.047994676517 -4.2714 0.1784 0.1127 0.2097 0.2249 0.0631 0.1466360 AQP3 aquaporin 3 (Gill blood group) 0.00016643885 0.00054432983 -4.2760 2.5104 2.1289 2.0575 1.8505 2.1640 1.51704837 NNMT nicotinamide N-methyltransferase 0.02617742087 0.049762155033 -4.2766 0.0591 0.1036 0.2143 0.0927 0.0527 0.28457582 ZNF33B zinc finger protein 33B 1.27876498E-14 2.03179076E-12 -4.2811 1.2067 0.8741 1.4138 1.1746 1.0272 1.87479369 NRXN3 neurexin 3 0.02280302246 0.044193553926 -4.2850 0.0399 0.1805 0.3192 0.1798 0.0473 0.1923

140678 MLLT10P1 0.00360523769 0.008787100643 -4.2861 0.0538 0.0533 0.0976 0.2120 0.1175 0.0999643847 PGA4 pepsinogen 4, group I (pepsinogen A) 0.01556020948 0.031756522677 -4.2936 0.0239 0.1442 0.1720 0.1454 0.0418 0.124029785 CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 0.00403800443 0.009735112402 -4.2974 0.4166 0.2752 1.0282 0.3187 0.1981 0.6718

643733 LOC643733 2.93837929E-06 1.38091735E-05 -4.3000 2.8635 2.2199 1.4863 2.3737 1.8077 1.22444883 NPR3 natriuretic peptide receptor 3 0.0001601844 0.000525757021 -4.3017 1.5380 2.3171 1.5786 1.0052 1.5366 1.039654209 TREM2 triggering receptor expressed on myeloid cells 2 0.02252927541 0.043709377826 -4.3034 0.0695 0.0889 0.2640 0.1894 0.0283 0.1535

338811 FAM19A2 0.00017024811 0.000555693732 -4.3057 1.4981 1.2237 1.0916 0.9648 0.9744 0.58802 A2M alpha-2-macroglobulin 0.0001054003 0.000360515606 -4.3061 0.7468 0.4989 0.5161 0.5300 0.3466 0.2725

162333 MARCH10 0.0220793527 0.042959635031 -4.3115 0.2563 0.3990 0.2681 0.2117 0.0982 0.25796616 SNAP25 synaptosomal-associated protein, 25kDa 0.00828162516 0.018315402438 -4.3149 0.5147 0.2913 1.4958 0.5669 0.1086 1.149726032 SUSD5 sushi domain containing 5 0.00931755864 0.020330837291 -4.3162 0.3048 0.1983 0.3606 0.6585 0.2674 0.45199975 NR1D2 nuclear receptor subfamily 1, group D, member 2 4.222263E-11 8.19863864E-10 -4.3165 1.8088 1.1969 1.6998 0.9511 0.7778 1.5770375190 FAM228B family with sequence similarity 228, member B 8.35249761E-08 5.65099893E-07 -4.3173 0.8347 0.7027 1.5725 0.6710 0.8449 0.9131

9705 ST18 0.01918661468 0.038069043701 -4.3203 0.0356 0.0062 0.0618 0.1476 0.0380 0.14997294 TXK TXK tyrosine kinase 1.64669929E-11 3.87738266E-10 -4.3273 1.4542 2.1438 0.9748 1.4489 1.5779 0.766310894 LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.01815403242 0.036276299254 -4.3282 0.0536 0.2586 0.0869 0.2215 0.0626 0.100079674 VEPH1 ventricular zone expressed PH domain-containing 1 0.00278915285 0.006988946903 -4.3333 0.1523 0.2808 0.2576 0.2258 0.0379 0.255310071 MUC12 mucin 12, cell surface associated 0.00080928158 0.002291877412 -4.3342 0.0299 0.0456 0.0959 0.1358 0.0366 0.1520

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2

melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10-like

similar to Caspase-4 precursor (CASP-4) (ICH-2 protease) (TX protease) (ICE(rel)-II)

family with sequence similarity 19 (chemokine (C-C motif)-like), member A2

membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase

suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)

154215 NKAIN2 Na+/K+ transporting ATPase interacting 2 0.02155299697 0.042101518405 -4.3359 0.6550 0.4312 0.5524 0.2780 0.6733 0.420510219 KLRG1 killer cell lectin-like receptor subfamily G, member 1 6.99012246E-06 3.03525469E-05 -4.3360 1.8838 1.3093 0.6688 1.9349 0.9700 0.43487060 THBS4 thrombospondin 4 4.9535852E-08 3.54115449E-07 -4.3378 0.4749 0.2832 1.5040 0.3677 0.4372 0.87612043 EPHA4 EPH receptor A4 1.40001258E-06 7.06971328E-06 -4.3422 2.9566 3.8209 1.9272 2.2168 2.9051 2.027284871 AGBL4 ATP/GTP binding protein-like 4 0.02628795018 0.049930709535 -4.3428 0.0751 0.1322 0.2526 0.1899 0.0883 0.34678343 HIST1H2BF histone cluster 1, H2bf 1.66779191E-09 1.82151188E-08 -4.3444 1.9614 2.7512 1.1333 0.8584 0.2119 0.954823544 SEZ6L seizure related 6 homolog (mouse)-like 0.01369541543 0.028410834551 -4.3459 0.1961 0.7078 0.1910 0.3407 0.8815 0.2448389289 ANXA2R chromosome 5 open reading frame 39 8.59242208E-06 3.66307955E-05 -4.3462 1.8514 4.2878 2.0630 2.1921 5.5577 3.337023506 GLTSCR1L GLTSCR1-like 2.66628671E-15 6.95977011E-13 -4.3495 1.5318 1.0735 0.5726 1.9152 1.0297 0.7334113791 PIK3IP1 phosphoinositide-3-kinase interacting protein 1 5.24409182E-08 3.7226125E-07 -4.3500 2.7867 3.2239 2.8359 3.1519 3.4531 3.1809909 CD1A CD1a molecule 0.02433327629 0.046801855195 -4.3500 0.0867 0.1214 0.1080 0.3229 0.2784 0.393180739 C6orf25 chromosome 6 open reading frame 25 0.00047784826 0.001416260068 -4.3523 0.3263 0.3149 0.3153 0.3635 0.3495 0.3755

223117 SEMA3D 0.00813964997 0.018053858255 -4.3549 0.0573 0.0904 0.1429 0.2470 0.1289 0.14175222 PGA5 pepsinogen 5, group I (pepsinogen A) 0.02322285883 0.044888191741 -4.3587 0.0376 0.1306 0.1393 0.3343 0.0065 0.10796886 TAL1 T-cell acute lymphocytic leukemia 1 0.00016718625 0.000546480708 -4.3589 0.5586 0.4877 0.4745 0.3885 0.3006 0.3580161497 STRC stereocilin 0.00036905433 0.001122210137 -4.3597 0.0451 0.0462 0.1459 0.1800 0.0471 0.1506219670 ENKUR chromosome 10 open reading frame 63 0.00019858909 0.000638954029 -4.3635 0.4200 0.3564 0.6102 0.4449 0.5462 0.3311728537 LOC728537 uncharacterized LOC728537 0.00014814337 0.000489754963 -4.3648 0.0640 0.0317 0.2253 0.0588 0.1437 0.119857125 PLXDC1 plexin domain containing 1 2.54008357E-06 1.21054791E-05 -4.3653 0.9178 1.6489 1.0586 0.8839 1.1028 1.10026252 RTN1 reticulon 1 0.00019610946 0.000631643231 -4.3669 0.8462 0.9156 0.5565 1.0923 0.5144 0.3723138649 ANKRD19P ankyrin repeat domain 19 1.51220184E-11 3.61661675E-10 -4.3708 1.0486 1.3994 1.6890 0.8381 1.2474 1.4524128102 HSD3BP4 hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 4 0.02375817318 0.045816289217 -4.3773 0.0535 0.0642 0.2098 0.1181 0.0587 0.15433791 KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.01865962947 0.037180888741 -4.3781 0.5498 0.2274 0.5064 0.4114 0.5049 0.40756095 RORA RAR-related orphan receptor A 5.75531526E-11 1.05583454E-09 -4.3802 0.7369 1.0656 0.9006 0.6683 0.7435 1.1203140711 TLDC2 chromosome 20 open reading frame 118 3.98374993E-06 1.81932214E-05 -4.3822 0.1600 0.0338 0.1541 0.6262 0.0245 0.1045

440253 WHAMMP2 4.4354895E-06 2.00756166E-05 -4.3828 1.2432 0.8431 0.7739 1.0435 0.6659 0.94439185 REPS2 RALBP1 associated Eps domain containing 2 0.00014631983 0.000484691053 -4.3836 0.5798 1.1123 0.8760 0.4683 0.7078 0.66734647 MYO7A myosin VIIA 0.01706784202 0.034380289876 -4.3925 0.3092 0.3203 0.4134 0.2527 0.2824 0.343555196 KIAA1551 KIAA1551 1.11290924E-10 1.81844708E-09 -4.3947 2.1818 1.8432 2.1556 2.6621 2.3408 2.9826114299 PALM2 paralemmin 2 0.00552031139 0.012819919895 -4.3993 0.2144 0.2163 0.2812 0.2846 0.3660 0.40163758 KCNJ1 potassium inwardly-rectifying channel, subfamily J, member 1 0.00051507531 0.001517242621 -4.4002 0.2410 0.2720 0.1527 0.3698 0.2846 0.23541003 CDH5 cadherin 5, type 2 (vascular endothelium) 0.02545031053 0.048577047327 -4.4032 0.0471 0.0801 0.1569 0.2247 0.0521 0.2648116285 ACSM1 acyl-CoA synthetase medium-chain family member 1 0.00213909878 0.005511225744 -4.4059 0.0614 0.0674 0.3033 0.1833 0.0446 0.2758326624 RAB37 RAB37, member RAS oncogene family 8.14907315E-08 5.52914462E-07 -4.4074 0.7156 1.3780 1.0755 0.8189 1.0407 0.8625368 ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.16204365E-05 4.80925518E-05 -4.4095 0.6536 1.3933 1.2683 0.3833 1.1573 0.849727324 TOX3 TOX high mobility group box family member 3 0.02424413538 0.046654959623 -4.4111 0.2794 0.4166 0.2178 0.8728 0.1751 0.200156204 FAM214A family with sequence similarity 214, member A 1.03294393E-12 4.42012915E-11 -4.4144 1.2299 1.5393 0.6849 1.0926 1.6801 1.1062

50859 SPOCK3 0.01784578822 0.035762035788 -4.4168 0.3825 0.4770 0.7246 0.4053 0.2474 0.36336947 TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00256777641 0.006496595202 -4.4182 0.0752 0.0463 0.4556 0.1965 0.0321 0.3908374864 CCDC178 chromosome 18 open reading frame 34 0.02597053733 0.049425440897 -4.4191 0.0893 0.0337 0.0876 0.1556 0.0563 0.0902400793 C1orf226 hypothetical gene supported by AK125122 0.01636484372 0.033154277024 -4.4246 0.0610 0.0286 0.1813 0.1383 0.0509 0.2116858 CAV2 caveolin 2 0.00073697264 0.002102086177 -4.4261 0.3766 0.7159 0.8860 0.3528 0.2616 0.5358160140 C11orf65 chromosome 11 open reading frame 65 9.78630502E-06 4.11922058E-05 -4.4303 2.3188 1.7273 1.2497 2.0695 2.2101 1.214884417 C2orf40 chromosome 2 open reading frame 40 4.67194024E-05 0.000171417052 -4.4304 1.2278 0.7879 1.0276 0.6801 0.8897 0.889279630 C1orf54 chromosome 1 open reading frame 54 0.00326283229 0.008038203215 -4.4357 0.0594 0.3119 0.3062 0.3657 0.2250 0.2455100129148 LOC100129148 uncharacterized LOC100129148 0.02201794502 0.042853612094 -4.4407 0.0942 0.0945 0.1593 0.3399 0.0590 0.2133

1102 RCBTB2 6.59547719E-09 5.9748418E-08 -4.4407 0.9136 1.2944 1.0091 0.9699 1.5479 1.3361534 ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 1.4328882E-06 7.22055521E-06 -4.4438 0.3321 0.3321 0.3321 0.3970 0.3970 0.397079083 MLPH melanophilin 0.01794719504 0.035937660035 -4.4440 0.1241 0.0955 0.2976 0.2770 0.0517 0.20572258 FGF13 fibroblast growth factor 13 0.02437974466 0.046866564371 -4.4445 0.2949 0.4608 0.8808 0.6000 0.2228 0.336423484 LEPROTL1 leptin receptor overlapping transcript-like 1 2.04142677E-16 1.69549772E-13 -4.4525 2.4597 5.2022 2.9611 2.9021 7.3324 3.7265201625 DNAH12 dynein heavy chain domain 2 0.00719193424 0.016156082205 -4.4622 0.2689 0.1765 0.2395 0.2590 0.1744 0.21205168 ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 2.32534827E-05 9.03075679E-05 -4.4629 0.8425 0.4643 0.5207 0.7357 0.3698 0.4236100507577 LOC100507577 uncharacterized LOC100507577 1.40878189E-10 2.20387522E-09 -4.4641 0.1325 0.1590 0.4547 0.1959 0.2173 0.26412045 EPHA7 EPH receptor A7 0.02006339901 0.039559558289 -4.4659 1.4860 2.0061 1.1168 1.3493 1.8797 0.781884519 ACRBP acrosin binding protein 7.23657759E-05 0.000256104485 -4.4666 0.4557 0.9112 0.6544 0.2755 1.0239 0.65197940 LST1 leukocyte specific transcript 1 1.67948372E-06 8.34353633E-06 -4.4668 0.5176 0.5091 0.5743 0.4962 0.4801 0.48767402 UTRN utrophin 7.77722948E-11 1.34061827E-09 -4.4670 0.9256 1.5093 1.1811 0.7887 1.3555 1.2454203447 NRK Nik related kinase 0.01735646779 0.034896278548 -4.4736 0.0344 0.0112 0.0624 0.1370 0.0202 0.109993649 MYOCD myocardin 0.0242914299 0.046736127951 -4.4742 0.0598 0.0445 0.2169 0.1420 0.0779 0.2943127435 PODN podocan 0.02210851474 0.043007216156 -4.4759 1.1193 1.6076 0.6969 0.5352 2.6224 0.47714868 NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.02551416168 0.048673497835 -4.4759 0.0667 0.2499 0.2152 0.1002 0.0956 0.26321513 CTSK cathepsin K 1.51607838E-08 1.23834529E-07 -4.4805 0.6009 0.5940 0.4674 0.3426 0.2668 0.2442100507387 LOC100507387 uncharacterized LOC100507387 6.21659101E-08 4.34044902E-07 -4.4815 0.0575 0.1074 0.1436 0.1318 0.1356 0.17489750 FAM65B family with sequence similarity 65, member B 8.20815768E-11 1.40298837E-09 -4.4837 2.4107 2.5060 1.9816 2.2586 2.0502 1.734723026 MYO16 myosin XVI 0.00311657832 0.007724649891 -4.4857 0.0790 0.0906 0.1044 0.2142 0.1975 0.1642286083 LOC286083 hypothetical protein LOC286083 0.02284543608 0.044252285387 -4.4866 0.1358 0.0449 0.1028 0.5335 0.0201 0.120493664 CADPS2 Ca2+-dependent activator protein for secretion 2 0.0186163084 0.037098613491 -4.4867 0.3131 0.2133 0.5737 0.3153 0.4219 0.5594255394 TCP11L2 t-complex 11 (mouse)-like 2 1.16601938E-08 9.78663581E-08 -4.4869 2.4320 2.3639 2.1780 2.4644 2.3423 2.2681441521 CT45A5 cancer/testis antigen CT45-5 0.02104297323 0.041263920041 -4.4871 0.2434 0.1918 0.2248 0.3251 0.2438 0.25965567 PRKACB protein kinase, cAMP-dependent, catalytic, beta 9.55031342E-10 1.12655472E-08 -4.4938 1.7487 2.0902 0.9388 1.3598 2.2167 0.8838440131 LINC00544 long intergenic non-protein coding RNA 544 0.00384404729 0.009301871557 -4.4961 1.9506 1.6349 1.9844 1.2563 0.6983 1.07052151 F2RL2 coagulation factor II (thrombin) receptor-like 2 0.00016102817 0.000528241788 -4.5023 0.0678 0.2482 0.1663 0.1500 0.1326 0.1998

23547 LILRA4 0.00093643807 0.002618701635 -4.5031 0.0847 0.0369 0.1946 0.2323 0.0271 0.2496137902 PXDNL peroxidasin homolog (Drosophila)-like 0.01235551 0.025988244355 -4.5048 0.0640 0.0542 0.0942 0.2329 0.1551 0.1192574028 CLLU1 chronic lymphocytic leukemia up-regulated 1 0.02627436598 0.049915569241 -4.5048 0.3707 0.6593 0.3886 0.4875 0.3983 0.27278277 TKTL1 transketolase-like 1 1.05006632E-05 4.38856627E-05 -4.5070 0.2183 0.1094 0.2612 0.5469 0.1266 0.1068693155 MIR570 microRNA 570 0.02147391208 0.041986638953 -4.5091 0.1070 0.0888 0.1014 0.2088 0.1870 0.14135730 PTGDS prostaglandin D2 synthase 21kDa (brain) 0.00021836238 0.000696685411 -4.5091 0.4102 0.7206 0.3263 0.3364 0.2302 0.2298

131096 KCNH8 0.02342203394 0.045230120913 -4.5093 0.6437 0.8010 0.6169 0.7606 0.7438 0.552051555 PEX5L peroxisomal biogenesis factor 5-like 0.01448345286 0.029835586323 -4.5143 0.4280 0.3466 0.5556 0.3986 0.2077 0.3524100422859 MIR3136 microRNA 3136 0.02039922047 0.040138868098 -4.5148 1.0168 0.9630 0.6163 0.9531 0.8441 0.536254800 KLHL24 kelch-like family member 24 6.90573577E-10 8.51427828E-09 -4.5164 0.8640 0.8822 0.6880 0.9651 1.5728 1.1714146853 C17orf50 chromosome17 open reading frame 50 0.01104571426 0.023555942779 -4.5199 0.0719 0.0849 0.1870 0.2857 0.1100 0.3026147372 CCBE1 collagen and calcium binding EGF domains 1 0.01988939067 0.039250345221 -4.5201 0.2897 0.1379 0.5906 0.2045 0.0486 0.4976

442117 GALNTL6 0.02457155119 0.047175725905 -4.5248 0.2697 0.2969 0.3169 0.2115 0.1344 0.2114729633 MRS2P2 MRS2 pseudogene 2 7.76422999E-05 0.000273612363 -4.5295 0.2605 0.3189 0.4643 0.7536 0.2874 0.7160155465 AGR3 anterior gradient homolog 3 (Xenopus laevis) 0.02502128536 0.047903282285 -4.5296 0.0214 0.0223 0.0569 0.1257 0.0279 0.162929018 FOXN3-AS2 FOXN3 antisense RNA 2 3.34062373E-07 1.95015581E-06 -4.5375 0.4666 0.3052 0.2763 0.4188 0.5216 0.39286158 RPL28 ribosomal protein L28 3.20418099E-17 8.75611785E-14 -4.5381 1.9390 3.6663 2.0250 2.1903 5.9831 2.7280256076 COL6A5 hypothetical protein FLJ35880 0.02393651854 0.046135872029 -4.5408 0.0399 0.0300 0.2962 0.1488 0.0255 0.24082049 EPHB3 EPH receptor B3 0.00366718149 0.008923523801 -4.5410 1.6185 1.2118 1.3962 0.9822 0.9149 0.9857163479 FNDC7 fibronectin type III domain containing 7 0.00532775741 0.012432794815 -4.5426 0.0478 0.0278 0.1706 0.2169 0.0336 0.0916150353 DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 5.6655357E-08 3.98156417E-07 -4.5440 0.3459 0.0551 0.2801 0.3650 0.0592 0.0842266977 GPR110 G protein-coupled receptor 110 0.02316507706 0.04478601595 -4.5463 0.0368 0.0388 0.1114 0.1112 0.0157 0.146627136 MORC1 MORC family CW-type zinc finger 1 0.01222958307 0.025750050924 -4.5510 0.0877 0.1749 0.0712 0.1405 0.0383 0.27794583 MUC2 mucin 2, oligomeric mucus/gel-forming 0.02459561979 0.04721201437 -4.5544 0.0325 0.2664 0.1634 0.0965 0.0249 0.08054842 NOS1 nitric oxide synthase 1 (neuronal) 0.01936302454 0.038364908303 -4.5600 0.0782 0.0270 0.1647 0.1665 0.0585 0.281281631 MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.11054439E-11 2.82616533E-10 -4.5616 1.7042 0.7360 2.7856 2.8446 0.6151 5.29613572 IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 6.60841266E-15 1.37214677E-12 -4.5640 1.3673 4.5151 0.5551 1.3550 12.4622 0.597754739 XAF1 XIAP associated factor 1 0.00053539515 0.001571524529 -4.5645 1.5141 1.7352 1.6475 1.6364 1.2954 0.959180763 C12orf39 chromosome 12 open reading frame 39 0.00122305821 0.00333498277 -4.5666 0.8679 0.9901 1.0681 0.8827 0.8601 1.0597100507346 LOC100507346 uncharacterized LOC100507346 0.00600629131 0.013804648412 -4.5677 1.6993 1.5420 1.6449 1.3053 1.2410 1.03181828 DSG1 TSC22 domain family, member 3 0.02536356141 0.048446894639 -4.5687 0.0539 0.0745 0.1436 0.1833 0.0368 0.1303100505495 LOC100505495 uncharacterized LOC100505495 0.02080373507 0.040858883335 -4.5714 0.0662 0.0563 0.2605 0.1875 0.2130 0.2444161253 REM2 RAS (RAD and GEM)-like GTP binding 2 8.67720835E-07 4.58104452E-06 -4.5736 0.4715 0.3399 0.4521 0.5307 0.1062 0.2704255631 COL24A1 collagen, type XXIV, alpha 1 0.00571862254 0.013228341696 -4.5766 0.2314 0.7822 0.3394 0.3781 0.2731 0.347689766 UMODL1 uromodulin-like 1 0.00343997543 0.008429023876 -4.5801 0.6327 0.4305 0.7337 0.5581 0.2431 0.4770346653 FAM71F2 family with sequence similarity 71, member F2 0.00769001531 0.017158622513 -4.5810 0.3154 0.3242 0.3143 0.1700 0.1610 0.2167204219 CERS3 LAG1 homolog, ceramide synthase 3 (S. cerevisiae) 0.00024263224 0.000768482616 -4.5822 0.4015 0.6654 0.3662 0.3442 0.2385 0.248483416 FCRL5 Fc receptor-like 5 0.00956183368 0.020791839233 -4.5831 0.1609 0.0769 0.1393 0.2343 0.0893 0.11851303 COL12A1 collagen, type XII, alpha 1 0.00569099234 0.01317292576 -4.5836 0.7759 0.7453 0.6794 0.4847 0.5890 0.3953100379132 SNORA70G small nucleolar RNA, H/ACA box 70G 0.00083479988 0.002357567758 -4.5843 0.7852 0.7009 0.4708 1.0357 0.5379 0.54312554 GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.02105220789 0.041277598722 -4.5858 0.1074 0.0502 0.1277 0.1795 0.0307 0.132625840 METTL7A methyltransferase like 7A 0.00032850851 0.001012276922 -4.5880 1.8177 2.1182 1.6410 1.2455 1.2511 0.7257912 CD1D CD1d molecule 0.00346104459 0.008476103297 -4.5931 1.0624 0.6873 0.7178 0.8824 0.6140 0.5328342035 GLDN gliomedin 0.01650908229 0.033394658649 -4.5967 0.1206 0.0572 0.3391 0.2754 0.0750 0.2835276 AMY1A amylase, alpha 1A (salivary) 3.59642793E-05 0.000134797807 -4.5994 0.0692 0.0078 0.1801 0.3082 0.1070 0.2178388325 SCIMP SLP adaptor and CSK interacting membrane protein 0.00454678112 0.010818958802 -4.6034 0.2301 0.3292 0.2077 0.1552 0.1806 0.20545816 PVALB parvalbumin 0.00271621692 0.006825844521 -4.6034 0.5525 0.5486 0.4260 0.3468 0.1567 0.288251411 BIN2 bridging integrator 2 1.53221586E-14 2.35265951E-12 -4.6040 1.8798 1.9910 1.4657 2.1509 2.4785 1.80731081 CGA glycoprotein hormones, alpha polypeptide 0.01772048749 0.035549928345 -4.6073 0.0418 0.7391 0.1829 0.1457 0.0438 0.164951816 CECR1 cat eye syndrome chromosome region, candidate 1 1.21485379E-05 5.01192334E-05 -4.6080 1.0628 0.9559 0.8077 1.0383 0.5792 0.406454207 KCNK10 potassium channel, subfamily K, member 10 0.00948456054 0.020653305941 -4.6087 0.2688 0.2983 0.2112 0.2253 0.1907 0.3117389432 SAMD5 sterile alpha motif domain containing 5 0.02135076392 0.041773333163 -4.6105 0.4679 3.0031 1.5951 1.3262 5.5746 0.85151641 DCX doublecortin 0.02136238969 0.041787691263 -4.6122 0.0301 0.0160 0.2467 0.2314 0.0669 0.1035129881 CCDC173 hypothetical LOC129881 2.57246412E-05 9.89976083E-05 -4.6127 2.3338 0.5853 0.9658 0.1897 0.2250 0.393923418 CRB1 crumbs family member 1, photoreceptor morphogenesis associated 0.00405195891 0.009761027448 -4.6138 0.8133 0.6419 0.6625 0.8407 0.5607 0.68643698 ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.00724013763 0.016253371137 -4.6146 0.0562 0.0294 0.0642 0.1728 0.0648 0.1299389136 VGLL3 vestigial like 3 (Drosophila) 0.0182418866 0.036434308794 -4.6153 0.3521 0.4670 0.5904 0.3390 0.4362 0.4819653653 LOC653653 similar to adaptor-related protein complex 1 sigma 2 subunit 6.69219552E-06 2.91837223E-05 -4.6189 0.9049 1.2108 1.0414 0.4971 1.6549 0.7051387707 CC2D2B chromosome 10 open reading frame 130 0.00122163278 0.003332090473 -4.6218 0.0715 0.0726 0.0872 0.1755 0.2501 0.162384059 GPR98 G protein-coupled receptor 98 0.00178017143 0.004664748643 -4.6279 0.2265 0.1763 0.3163 0.3279 0.0723 0.25581610 DAO D-amino-acid oxidase 0.02472196023 0.047424635945 -4.6285 0.3709 1.0474 0.8857 0.3682 0.4181 0.52647018 TF transferrin 0.0092090704 0.020118358936 -4.6327 0.1746 0.1020 0.3003 0.2367 0.0701 0.31584925 NUCB2 nucleobindin 2 1.09924421E-12 4.64939587E-11 -4.6346 0.5135 0.5849 0.6597 0.5528 0.5487 0.6719266722 HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.02288248092 0.044309950341 -4.6368 0.2291 0.4467 0.4128 0.3033 0.0599 0.3785

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D

WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 2

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4

potassium voltage-gated channel, subfamily H (eag-related), member 8

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6

6039 RNASE6 ribonuclease, RNase A family, k6 0.00342988611 0.008405429049 -4.6370 2.5781 0.9205 1.2513 1.6131 0.7685 0.6847388685 FLJ39739 uncharacterized FLJ39739 8.39333971E-12 2.27114953E-10 -4.6382 2.2728 2.4300 1.6702 2.9639 3.2839 2.94441630 DCC deleted in colorectal carcinoma 0.01464235447 0.030118777548 -4.6396 0.0824 0.0560 0.1045 0.2306 0.0255 0.32141746 DLX2 distal-less homeobox 2 0.00958756416 0.020837869914 -4.6404 1.0722 1.7973 1.6667 0.6514 1.4798 1.3706

5345 SERPINF2 0.0010418746 0.002880922027 -4.6427 0.0633 0.0200 0.1293 0.0581 0.1276 0.1071115677 NOSTRIN nitric oxide synthase trafficking 4.13553778E-05 0.000153399404 -4.6441 0.1285 0.1082 0.3468 0.1597 0.0736 0.25802690 GHR growth hormone receptor 0.02060753663 0.040501334764 -4.6442 0.1759 0.4315 0.3048 0.2142 0.5944 0.252722798 LAMB4 laminin, beta 4 0.01674261696 0.033801446518 -4.6486 0.0631 0.0279 0.2506 0.2002 0.0246 0.321183872 HMCN1 hemicentin 1 0.00661707 0.015036255911 -4.6505 0.4498 0.2116 0.4434 0.4400 0.1750 0.230755777 MBD5 methyl-CpG binding domain protein 5 2.44065938E-14 3.14890479E-12 -4.6508 0.1883 0.1367 0.1876 0.3053 0.1796 0.2340388743 CAPN8 similar to calpain 8 0.01276205668 0.026723389824 -4.6563 0.0454 0.1484 0.2171 0.3176 0.0469 0.149523224 SYNE2 spectrin repeat containing, nuclear envelope 2 3.3266438E-10 4.62943149E-09 -4.6575 0.3008 0.5950 0.2480 0.3406 0.5068 0.281526788 SNORD60 small nucleolar RNA, C/D box 60 0.01452255311 0.029909388016 -4.6581 1.3975 2.9726 3.2734 0.7639 6.1204 2.9094219731 PROSER2-AS1 hypothetical protein LOC219731 0.02209420462 0.042983955151 -4.6594 0.0377 0.0185 0.1316 0.0633 0.0308 0.108022885 ABLIM3 actin binding LIM protein family, member 3 0.00381381132 0.009234821161 -4.6642 0.4770 0.5945 0.5670 0.5083 0.7900 0.4910643832 GAGE10 G antigen 10 0.00434458143 0.010385163783 -4.6646 0.1260 0.1533 0.0675 0.1060 0.0813 0.135850939 IMPG2 interphotoreceptor matrix proteoglycan 2 2.00490345E-05 7.89347034E-05 -4.6675 0.0636 0.1420 0.1146 0.3721 0.1111 0.18313078 CFHR1 complement factor H-related 1 0.00393417912 0.00950335958 -4.6687 0.0858 0.0623 0.1329 0.2623 0.1177 0.2283121227 LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 0.01809754881 0.036179257324 -4.6722 0.2931 0.4737 0.8368 0.3373 0.5928 0.8830157695 TDRP testis development related protein 0.00157491984 0.00418817279 -4.6758 1.0308 0.9579 0.5066 0.7098 0.2983 0.6935348120 CT60 hypothetical protein LOC348120 0.01366237194 0.028356098668 -4.6760 0.2318 0.1256 0.1357 0.1761 0.0601 0.1838406951 MIR16-2 microRNA 16-2 0.01147283275 0.024355942829 -4.6772 1.3833 0.5063 0.0318 0.2398 0.1208 0.2722143630 UBQLNL ubiquilin-like 0.00308866279 0.007664816864 -4.6809 0.0196 0.0720 0.2715 0.2156 0.0377 0.2381345275 HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 0.00088167544 0.002479983635 -4.6844 0.1187 0.1012 0.0988 0.2561 0.0213 0.2455731789 LINC00202-2 long intergenic non-protein coding RNA 202-2 0.01295617949 0.027077125891 -4.6844 0.0522 0.0887 0.1661 0.1624 0.0607 0.1531440225 NF1P2 neurofibromin 1 pseudogene 2 0.01517796098 0.03108054499 -4.6865 0.2067 0.1467 0.1614 0.2241 0.0617 0.1616860 RUNX2 runt-related transcription factor 2 2.13378536E-07 1.3083398E-06 -4.6920 2.0391 1.8807 1.2190 1.2076 1.3572 1.71357498 XDH xanthine dehydrogenase 0.00882095505 0.019360539412 -4.6944 0.2418 0.4887 0.3436 0.5570 0.3007 0.23944208 MEF2C myocyte enhancer factor 2C 0.00042159018 0.001265239868 -4.6958 0.6811 0.4468 0.6826 0.5424 0.4203 0.44647252 TSHB thyroid stimulating hormone, beta 0.02382069068 0.045932002975 -4.6963 0.0660 0.0442 0.0890 0.1956 0.1053 0.14785462 POU5F1B POU class 5 homeobox 1B 8.44502527E-05 0.000295239821 -4.6976 0.0681 0.1235 0.2437 0.5649 0.0902 0.2450735301 SNHG9 small nucleolar RNA host gene 9 (non-protein coding) 1.04147139E-09 1.21285948E-08 -4.6977 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970255928 SYT14 synaptotagmin XIV 0.01535085366 0.03137256203 -4.6993 0.2940 0.3503 0.3870 0.4314 0.3654 0.31129936 CD302 CD302 molecule 0.00314405137 0.007784296294 -4.7010 1.2812 1.5493 0.8739 0.9188 1.2486 0.49634319 MMP10 matrix metallopeptidase 10 (stromelysin 2) 0.01136305349 0.024145332415 -4.7026 0.0502 0.0215 0.1736 0.1054 0.0568 0.10472903 GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.01360135032 0.028257404546 -4.7027 0.2592 0.4771 0.1997 0.3447 0.1250 0.2955340120 ANKRD34B cytosolic phosphoprotein DP58 0.00800403287 0.017778955591 -4.7039 0.3938 0.5021 0.6379 0.3798 0.2029 0.60601471 CST3 cystatin C 0.00030296721 0.00094066556 -4.7047 0.6947 1.4954 1.0633 0.4210 0.9717 0.7767131034 CPNE4 copine IV 0.02124912996 0.041605668951 -4.7059 0.1044 0.1006 0.1571 0.3080 0.1675 0.2094643719 SCGB1B2P secretoglobin, family 1B, member 2, pseudogene 0.0041331731 0.009938325951 -4.7064 0.0548 0.3745 0.1530 0.5999 0.0222 0.243654456 MOV10L1 Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) 0.01285130685 0.026882550514 -4.7079 0.1221 0.1749 0.3166 0.2049 0.1292 0.19106096 RORB RAR-related orphan receptor B 0.00508144833 0.011946503335 -4.7136 1.3366 0.4997 0.8155 1.0932 0.5727 0.54636262 RYR2 ryanodine receptor 2 (cardiac) 0.00309315248 0.007673719273 -4.7141 0.1099 0.2270 0.2237 0.1680 0.0912 0.2479761 CA3 carbonic anhydrase III, muscle specific 0.00947113234 0.020626523253 -4.7175 0.1846 0.3288 0.7592 0.2847 0.1695 0.604110209 EIF1 eukaryotic translation initiation factor 1 6.84368718E-11 1.2164188E-09 -4.7197 2.3113 2.9153 2.0388 2.1572 3.5231 2.9101692058 SNORD11 small nucleolar RNA, C/D box 11 0.0084521158 0.018649566473 -4.7222 0.0796 0.1941 0.4528 0.1866 0.0547 0.4101389761 SPATA31D4 SPATA31 subfamily D, member 4 0.0136043528 0.028260429109 -4.7223 0.0518 0.0397 0.2167 0.2235 0.2330 0.1229389715 FAM205B transmembrane protein C9orf144B pseudogene 0.02147981011 0.041989845981 -4.7230 0.0583 0.0816 0.1486 0.5377 0.1068 0.1375595097 SNORD16 small nucleolar RNA, C/D box 16 0.01220366282 0.025698435756 -4.7254 0.3321 0.3321 0.3321 0.3970 0.3970 0.39702498 FTH1P3 ferritin, heavy polypeptide 1 pseudogene 3 6.30175645E-10 7.91923617E-09 -4.7257 0.3836 0.2759 0.3495 0.6331 0.1111 0.2199577 BAI3 brain-specific angiogenesis inhibitor 3 0.02569128069 0.048960271261 -4.7285 1.1649 1.3313 0.9026 1.0934 1.2009 0.702557010 CABP4 calcium binding protein 4 3.92795902E-05 0.000146442904 -4.7291 0.1054 0.1209 0.1923 0.2725 0.0489 0.3358440712 C1orf186 chromosome 1 open reading frame 186 0.00034371775 0.001053937037 -4.7319 0.2038 0.2441 0.6540 0.3171 0.1920 0.4696693215 MIR630 microRNA 630 0.00347657057 0.00850956429 -4.7325 0.0934 0.0813 0.0593 0.1067 0.0091 0.076629953 TRHDE thyrotropin-releasing hormone degrading enzyme 0.01740603103 0.034984380037 -4.7346 0.9633 0.3584 1.2907 0.4062 0.1925 1.317150507 NOX4 NADPH oxidase 4 0.01572971375 0.032030907119 -4.7450 0.0494 0.0334 0.1433 0.1533 0.0509 0.20107173 TPO thyroid peroxidase 0.00303780933 0.007550925328 -4.7452 0.0721 0.1510 0.1580 0.1070 0.1014 0.15789445 ITM2B integral membrane protein 2B 1.84121096E-10 2.76674191E-09 -4.7474 2.3143 1.5292 2.1558 2.3138 1.9302 2.8974644150 WIPF3 WAS/WASL interacting protein family, member 3 0.01557482532 0.031775704369 -4.7508 0.1686 0.2073 0.4829 0.3081 0.1177 0.37644986 OPRK1 opioid receptor, kappa 1 0.0166756127 0.033690490415 -4.7516 0.0613 0.3103 0.3224 0.3212 0.1922 0.490610896 OCLM oculomedin 0.00164604084 0.004355750643 -4.7541 0.1147 0.0391 0.2473 0.1874 0.1812 0.35849027 NAT8 N-acetyltransferase 8 (GCN5-related, putative) 0.01302134591 0.027204408241 -4.7548 0.0242 0.0393 0.1975 0.0689 0.0495 0.12344070 TACSTD2 tumor-associated calcium signal transducer 2 0.00021099784 0.000675193094 -4.7556 0.5623 0.9419 1.2180 0.4569 0.6393 0.928757529 RGAG1 retrotransposon gag domain containing 1 0.01590933326 0.032339007386 -4.7661 0.0960 0.1114 0.1475 0.1616 0.0124 0.210129993 PACSIN1 protein kinase C and casein kinase substrate in neurons 1 5.16377441E-06 2.30855438E-05 -4.7672 0.1899 0.2075 0.3967 0.1866 0.2648 0.3584389762 SPATA31D3 SPATA31 subfamily D, member 3 0.01806070221 0.036125358605 -4.7694 0.0308 0.0484 0.2221 0.3143 0.2993 0.125954768 HYDIN HYDIN, axonemal central pair apparatus protein 0.00096861213 0.00269917354 -4.7697 0.0489 0.0723 0.1379 0.2282 0.2288 0.1878166336 PRICKLE2 prickle homolog 2 (Drosophila) 0.01602165495 0.032538366044 -4.7718 0.2697 0.3311 0.3510 0.2816 0.1892 0.1792644041 C18orf63 hypothetical protein LOC644041 0.02469422864 0.047381386715 -4.7766 0.0110 0.1130 0.0728 0.2565 0.0150 0.21802315 MLANA melan-A 0.00047782574 0.001416260068 -4.7783 0.0711 0.0173 0.2607 0.3662 0.0280 0.210379153 GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 8.57394904E-08 5.78947513E-07 -4.7785 0.1708 0.2194 0.1752 0.2328 0.0482 0.2412406976 MIR199A1 microRNA 199a-1 0.01909090882 0.037912084125 -4.7795 0.0250 0.0504 0.0801 0.1131 0.0182 0.1550400620 LOC400620 uncharacterized LOC400620 0.01957920121 0.038717658493 -4.7800 0.0997 0.0268 0.1520 0.2549 0.0284 0.16394308 TRPM1 transient receptor potential cation channel, subfamily M, member 1 0.01723273486 0.034670395432 -4.7802 0.0684 0.0244 0.1077 0.1079 0.2338 0.21933045 HBD hemoglobin, delta 0.00830435444 0.018356782531 -4.7816 0.1475 0.1005 0.1538 0.0865 0.0141 0.130693377 OPALIN oligodendrocytic myelin paranodal and inner loop protein 0.01564760899 0.031892148514 -4.7835 0.0431 0.0487 0.1642 0.1639 0.0259 0.1633401242 LOC401242 uncharacterized LOC401242 0.02011963037 0.039661871405 -4.7849 0.5913 0.5295 0.4612 0.6435 0.5982 0.54122352 FOLR3 folate receptor 3 (gamma) 0.00236381409 0.00602477486 -4.7865 0.1001 0.1670 0.3804 0.3003 0.0422 0.25182847 MCHR1 melanin-concentrating hormone receptor 1 0.00226051417 0.005784794345 -4.7873 0.2151 0.3896 0.6052 0.0967 0.2110 0.3048301 ANXA1 annexin A1 8.95231241E-08 6.00281293E-07 -4.7897 2.1901 1.6282 1.1720 1.6714 0.8785 0.6049374462 PTPRQ protein tyrosine phosphatase, receptor type, Q 0.01612215231 0.032731551887 -4.7931 0.0695 0.1008 0.0712 0.0758 0.1612 0.1192768218 MIR766 microRNA 766 0.00966361084 0.020978198561 -4.7993 0.4138 0.7066 1.3387 0.3933 0.1704 0.6206440926 H3F3AP4 H3 histone, family 3A, pseudogene 4 2.49902535E-07 1.50254002E-06 -4.8017 2.5565 1.8249 1.0315 4.1408 3.1692 2.04102813 GP2 glycoprotein 2 (zymogen granule membrane) 0.01868474804 0.03722282121 -4.8064 0.0523 0.0060 0.0699 0.2129 0.0070 0.1302285550 FAM200B family with sequence similarity 200, member B 2.32690634E-12 8.22383611E-11 -4.8069 2.0185 3.4526 1.4186 2.2889 3.5829 2.610155410 TTTY14 non-protein coding RNA 185 9.50853027E-05 0.000328182594 -4.8099 0.1511 0.0558 0.0904 0.2491 0.0989 0.5391693158 MIR573 microRNA 573 0.01893301888 0.037627161296 -4.8102 0.0589 0.1609 0.1521 0.1055 0.0388 0.1155727940 RHOXF2B Rhox homeobox family, member 2B 0.0079363126 0.0176499883 -4.8122 0.0307 0.0942 0.4403 0.5408 0.0060 0.2511158471 PRUNE2 prune homolog 2 (Drosophila) 0.00022886118 0.000727261132 -4.8210 0.5002 0.2199 0.4444 0.5747 0.4464 0.3299401124 DTHD1 FLJ16686 protein 2.02279024E-05 7.96046163E-05 -4.8213 0.3183 0.4425 0.7201 0.3733 0.3163 0.35017476 WNT7A wingless-type MMTV integration site family, member 7A 1.19778448E-07 7.78027657E-07 -4.8224 1.8075 1.2603 1.7107 1.3701 0.9640 1.1067

3116 HLA-DPB2 0.00328580776 0.008085963556 -4.8238 0.3122 0.3100 0.3214 0.3725 0.3781 0.37881524 CX3CR1 chemokine (C-X3-C motif) receptor 1 4.79889561E-05 0.000175616704 -4.8252 0.2973 0.2072 0.2478 0.3804 0.2270 0.2711100132994 CXorf49B chromosome X open reading frame 49B 0.01136161048 0.024145332415 -4.8287 0.0161 0.2926 0.3491 0.3065 0.2789 0.265383719 YPEL3 yippee-like 3 (Drosophila) 1.83698633E-08 1.46894591E-07 -4.8293 1.1182 1.6348 1.7340 1.0397 1.7490 1.53315334 PLCL1 phospholipase C-like 1 5.27183734E-09 4.92748088E-08 -4.8313 2.0855 2.5864 2.2040 1.8070 2.2240 2.48609214 FAIM3 Fas apoptotic inhibitory molecule 3 9.71667376E-10 1.14131986E-08 -4.8340 2.7890 2.3505 3.4122 3.1826 1.8816 2.460426050 SLITRK5 SLIT and NTRK-like family, member 5 0.00513805406 0.012054766794 -4.8385 0.7607 2.4870 0.6014 0.8403 1.5482 0.3865100506658 OCLN occludin 3.01911864E-07 1.78067578E-06 -4.8390 0.2834 0.6074 0.7397 0.2224 0.6140 0.743880731 THSD7B thrombospondin, type I, domain containing 7B 0.01440577136 0.02968895267 -4.8396 0.1382 0.3075 0.3506 0.3890 0.2584 0.3002152503 SH3D19 SH3 domain containing 19 1.36084E-06 6.90126796E-06 -4.8402 0.0659 0.0325 0.0877 0.2291 0.0621 0.131554809 SAMD9 sterile alpha motif domain containing 9 2.51200196E-06 1.19935458E-05 -4.8414 4.8010 2.7358 1.7136 4.1893 2.3015 0.9902164684 WBP2NL WBP2 N-terminal like 8.87370255E-05 0.000308544801 -4.8423 0.5087 0.8044 0.7058 0.4465 0.7135 0.7152730262 PPIAL4E peptidylprolyl isomerase A (cyclophilin A)-like 4E 0.00523748752 0.0122565794 -4.8428 0.7544 0.5816 0.3275 1.0384 0.6728 0.3087100616209 MIR4461 microRNA 4461 0.01040775182 0.022388796952 -4.8473 0.0838 0.1308 0.2333 0.1236 0.1261 0.1971113157 RPLP0P2 ribosomal protein, large, P0 pseudogene 2 5.38923507E-06 2.40117296E-05 -4.8500 0.0288 0.0983 0.1461 0.0197 0.0361 0.1846815 CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.01410639547 0.029167371057 -4.8512 0.0452 0.0260 0.1905 0.2155 0.0173 0.16275997 RGS2 regulator of G-protein signaling 2, 24kDa 1.65546203E-07 1.0423364E-06 -4.8519 1.7967 1.9232 1.8355 1.5973 2.0778 2.2225

8499 PPFIA2 0.01707725637 0.034387880585 -4.8530 0.1591 0.2072 0.2129 0.2866 0.2386 0.2564

8483 CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00113027151 0.003108884682 -4.8548 0.2140 0.0881 0.2855 0.1340 0.0293 0.20112115 ETV1 ets variant 1 0.01784308507 0.035760540785 -4.8549 0.6556 0.4869 0.8235 0.7464 0.5376 0.671429116 MYLIP myosin regulatory light chain interacting protein 3.66720077E-13 2.10421995E-11 -4.8552 1.4126 2.4892 1.6245 1.5971 1.9924 2.28816281 S100A10 S100 calcium binding protein A10 1.01873941E-11 2.63660148E-10 -4.8558 1.2599 1.6735 1.2340 1.1436 1.7542 1.2094170622 COMMD6 COMM domain containing 6 8.05364715E-15 1.51707465E-12 -4.8580 2.1566 2.3024 1.8388 2.0368 2.0817 2.3136149954 BPIFB4 chromosome 20 open reading frame 186 0.01988579212 0.039247482575 -4.8589 0.0083 0.0537 0.1536 0.0892 0.0274 0.182664600 PLA2G2F phospholipase A2, group IIF 0.02159595367 0.042180787327 -4.8614 0.0127 0.1802 0.1313 0.0707 0.0557 0.108753820 RIPPLY3 ripply transcriptional repressor 3 0.00884636567 0.019411648078 -4.8620 0.5302 2.6558 1.2975 0.2432 1.8444 1.4396387357 THEMIS thymocyte selection associated 2.39718485E-10 3.50130788E-09 -4.8631 2.1176 1.9850 1.2424 1.5710 1.1653 0.94631768 DNAH6 dynein, axonemal, heavy chain 8 7.90270211E-07 4.20985927E-06 -4.8676 1.1807 0.9090 0.5232 0.9926 0.9588 0.36582044 EPHA5 EPH receptor A5 0.00903064203 0.019768526567 -4.8761 0.4050 0.0798 0.3372 0.3794 0.0782 0.35172913 GRM3 glutamate receptor, metabotropic 3 0.00608513345 0.013964777494 -4.8766 0.1457 0.1076 0.3199 0.1869 0.0528 0.241427098 CLUL1 clusterin-like 1 (retinal) 0.0056878384 0.013168801735 -4.8772 0.4056 0.6187 0.8602 0.3141 0.2015 0.5075643834 PGA3 pepsinogen 3, group I (pepsinogen A) 0.00581719294 0.013420675424 -4.8776 0.0270 0.1166 0.1120 0.2488 0.0533 0.0971645752 LOC645752 golgin A6 family, member A pseudogene 0.01316052845 0.027447685859 -4.8797 0.0516 0.0315 0.1335 0.4122 0.0271 0.16395506 PPP1R3A protein phosphatase 1, regulatory subunit 3A 0.01670317971 0.03373126654 -4.8812 0.0521 0.0139 0.0657 0.2139 0.0207 0.13678796 SCEL sciellin 0.0137263494 0.028462080817 -4.8842 0.0537 0.2471 0.2223 0.1027 0.0624 0.2093728062 CT47A6 cancer/testis CT47 family, member 6 0.01161700311 0.024636244296 -4.8896 0.0144 0.0587 0.1336 0.4157 0.0522 0.174226033 ATRNL1 attractin-like 1 0.00350950692 0.00858443246 -4.8923 0.4924 0.5126 0.7988 0.5642 0.3444 0.895026791 SNORD58A small nucleolar RNA, C/D box 58A 0.01669384879 0.033723604762 -4.8933 0.2274 0.8131 1.3118 0.5897 1.1426 0.6377693232 MIR647 microRNA 647 0.00755136864 0.0168863796 -4.8940 0.2004 0.3122 0.4436 0.1679 0.3108 0.338383888 FGFBP2 fibroblast growth factor binding protein 2 0.00030804409 0.000954806027 -4.8945 0.7645 0.9502 1.6568 0.5891 0.7516 0.71671770 DNAH9 deoxyribonuclease I-like 1 0.01705231067 0.034352791691 -4.8966 0.0465 0.1357 0.3677 0.2559 0.1846 0.3280162517 FBXO39 F-box protein 39 0.00887388047 0.019458003584 -4.8996 0.1938 0.4793 0.2949 0.3013 0.6996 0.37247643 ZNF90 zinc finger protein 90 5.78516783E-13 2.97765033E-11 -4.9012 1.8507 1.8879 1.4557 1.2229 2.2436 1.636484944 MAEL maelstrom spermatogenic transposon silencer 0.01024957081 0.022095346614 -4.9032 0.3992 0.4500 0.4886 0.3754 0.3689 0.352751440 HPCAL4 hippocalcin like 4 6.17746499E-07 3.37644751E-06 -4.9032 1.1324 2.4038 2.0718 0.7418 1.4197 1.6900100506428 CBR3-AS1 CBR3 antisense RNA 1 2.25917635E-07 1.37369951E-06 -4.9054 1.0849 2.4731 1.1998 1.5565 2.1314 1.777810957 PNRC1 proline-rich nuclear receptor coactivator 1 2.05891853E-12 7.5847902E-11 -4.9061 2.2441 2.9271 1.2140 3.3202 4.5780 2.4005400084 LINC00939 long intergenic non-protein coding RNA 939 0.02397211309 0.046199604516 -4.9065 0.2423 0.1863 0.3211 0.2231 0.0580 0.12885545 PRB4 proline-rich protein BstNI subfamily 4 0.01039283798 0.022359347187 -4.9070 0.0750 0.0769 0.1933 0.2814 0.0434 0.3129

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

major histocompatibility complex, class II, DP beta 2 (pseudogene),NR_001435

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

139378 GPR112 G protein-coupled receptor 112 0.01405442231 0.029081443124 -4.9102 0.0198 0.0870 0.1280 0.2089 0.0338 0.225427329 ANGPTL3 angiopoietin-like 3 0.00551072825 0.012800918721 -4.9121 0.0864 0.0117 0.0737 0.2876 0.0330 0.13004213 MEIS3P1 Meis homeobox 3 pseudogene 1 0.00324672679 0.008004883529 -4.9142 0.1829 0.3270 0.3134 0.5929 0.7421 0.275157576 KIF17 kinesin family member 17 0.00587411635 0.013536619231 -4.9151 0.2366 0.3801 0.3286 0.2714 0.3480 0.3920

5288 PIK3C2G 0.02065354327 0.040583024271 -4.9164 0.0130 0.0285 0.1614 0.1586 0.0634 0.106023316 CUX2 cut-like homeobox 2 0.00088265232 0.002482349254 -4.9193 1.1634 1.3757 0.7409 0.9281 1.3382 0.536110144 FAM13A family with sequence similarity 13, member A 9.24374285E-08 6.17556378E-07 -4.9211 1.3602 1.4330 0.9334 1.1377 1.2193 0.8823846 CASR calcium-sensing receptor 0.01110397937 0.023660864257 -4.9229 0.0888 0.3801 0.4785 0.2724 0.2539 0.3973154075 SAMD3 sterile alpha motif domain containing 3 4.35001476E-09 4.17894162E-08 -4.9279 1.5391 1.6278 0.7330 1.0982 0.6075 0.3254646626 LOC646626 uncharacterized LOC646626 0.00670960826 0.015220107025 -4.9291 4.7021 5.8176 3.3140 3.9872 4.5810 2.3204472 ATM ataxia telangiectasia mutated 1.47924134E-11 3.55688357E-10 -4.9310 1.1133 0.5639 0.6207 1.3080 0.6288 0.5796340205 TREML1 triggering receptor expressed on myeloid cells-like 1 8.78979631E-05 0.000305918397 -4.9316 0.0848 0.0279 0.1769 0.1843 0.0456 0.1547

10371 SEMA3A 0.0020201615 0.00523431521 -4.9339 2.2084 1.8133 1.3173 1.9739 1.5374 1.054955853 IDI2-AS1 IDI2 antisense RNA 1 5.96081259E-10 7.55836E-09 -4.9340 0.0569 0.3125 0.1842 0.2136 0.7377 0.300555089 SLC38A4 solute carrier family 38, member 4 0.00920323668 0.020112611009 -4.9388 0.1516 0.0273 0.1558 0.2301 0.0327 0.23121769 DNAH8 dynein, axonemal, heavy chain 9 0.00270502629 0.006801464192 -4.9395 0.3523 0.3758 0.9134 0.2584 0.4380 0.5893121601 ANO4 transmembrane protein 16D 0.01294742846 0.027061932373 -4.9425 0.0778 0.0513 0.1568 0.2026 0.0819 0.2202387700 SLC16A12 solute carrier family 16, member 12 0.01084956378 0.023194481024 -4.9439 0.4028 0.2513 0.4291 0.3883 0.4245 0.4362126204 NLRP13 NLR family, pyrin domain containing 13 0.02263169009 0.043894092053 -4.9441 0.0151 0.0133 0.1534 0.1031 0.5647 0.14201197 CLK2P CDC-like kinase 2, pseudogene 0.00214285016 0.005519334377 -4.9451 0.2096 0.0526 0.0607 0.3685 0.0655 0.2159283767 GOLGA6L1 FLJ40198 protein 0.02239767224 0.043500240985 -4.9492 0.0830 0.0939 0.1935 0.3471 0.3072 0.18752533 FYB FYN binding protein 3.37103157E-10 4.67352492E-09 -4.9535 1.5831 1.2932 1.2033 1.6027 1.3086 1.0459285025 CCDC141 hypothetical protein FLJ39502 1.69056863E-08 1.36042921E-07 -4.9542 1.2812 1.5686 0.9896 1.1989 1.6160 0.83683075 CFH complement factor H 1.09656417E-06 5.66640851E-06 -4.9553 0.4419 1.1179 0.4485 0.3149 2.0034 0.3051388951 TSPYL6 TSPY-like 6 0.00639961153 0.014609408027 -4.9560 0.0390 0.0261 0.2894 0.5152 0.5105 0.288810870 HCST hematopoietic cell signal transducer 2.74490152E-11 5.87981718E-10 -4.9582 2.7780 2.9398 3.2826 2.1147 2.1903 2.818451705 EMCN endomucin 0.01581930135 0.032181059261 -4.9589 0.2100 0.1999 0.1681 0.3842 0.1428 0.237593986 FOXP2 forkhead box P2 0.00694171085 0.015672672756 -4.9595 0.2072 0.4260 0.2432 0.2930 0.3702 0.2762646113 LINC00643 long intergenic non-protein coding RNA 643 0.01424604462 0.029402883461 -4.9604 1.1019 1.3363 0.8642 0.8935 1.1804 0.5413126767 AADACL3 arylacetamide deacetylase-like 3 0.02093159137 0.041071954196 -4.9639 0.0558 0.0197 0.0967 0.2048 0.0080 0.1359149992 ANKRD30BP2 chromosome 21 open reading frame 99 0.00762586905 0.017027970102 -4.9648 0.0149 0.0092 0.0766 0.1616 0.0743 0.21956285 S100B S100 calcium binding protein B 0.00043033751 0.001288192494 -4.9665 0.7990 0.5768 0.5876 0.4888 0.3437 0.31754624 MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.00094869859 0.002650148394 -4.9699 0.0146 0.1485 0.3024 0.1553 0.0041 0.15742006 ELN elastin 0.01524998834 0.031203559562 -4.9717 0.3026 0.2458 0.2752 0.3659 0.0222 0.402057687 VAT1L vesicle amine transport 1-like 0.00800273345 0.01777823046 -4.9731 0.5462 1.1615 0.8720 0.4014 0.4976 0.7968339529 LOC339529 uncharacterized LOC339529 0.00824281833 0.018245617654 -4.9779 2.3019 2.0017 1.3569 1.4484 1.4606 0.9691

151254 ALS2CR11 0.00620840602 0.014216588578 -4.9839 0.1212 0.0941 0.2301 0.3925 0.0367 0.21215801 PTPRR protein tyrosine phosphatase, receptor type, R 0.01310111044 0.027345612282 -4.9849 0.0890 0.0609 0.1314 0.1733 0.0468 0.1285440561 PRAMEF6 PRAME family member 6 0.01952482798 0.038647779968 -4.9855 0.0453 0.0238 0.1140 0.1452 0.0269 0.1862126520 PLK5 hypothetical protein LOC126520 0.01650008253 0.03338014925 -4.9892 0.0613 0.0744 0.1844 0.0957 0.3433 0.097553942 CNTN5 contactin 5 0.0131204343 0.027376564525 -4.9893 0.2396 0.2022 0.2678 0.2512 0.0650 0.18114118 MAL mal, T-cell differentiation protein 9.78706334E-12 2.55835796E-10 -4.9914 1.4446 4.0061 1.7014 1.2941 3.4530 2.7089100033438 SNORD116-26 small nucleolar RNA, C/D box 116-26 0.00528953701 0.012354649141 -4.9926 0.0894 0.0331 0.0584 1.1183 0.2419 0.194489822 KCNK17 potassium channel, subfamily K, member 17 0.00838152464 0.018507216701 -4.9937 0.2329 0.5454 0.6576 0.1935 0.3961 0.438766000 TMEM108 transmembrane protein 108 0.00454164135 0.010808136331 -5.0062 0.2309 0.6151 0.4591 0.5839 0.8921 0.5280340024 SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 0.02358732771 0.045525261645 -5.0082 0.0276 0.8196 0.1198 0.1531 0.0175 0.17753174 HNF4G hepatocyte nuclear factor 4, gamma 0.01389315429 0.028775302097 -5.0100 0.4783 0.3460 0.4320 0.5180 0.1826 0.43494325 MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.0136628225 0.028356098668 -5.0126 0.2877 1.3476 0.6506 0.4675 1.0677 0.4653644669 LOC644669 hypothetical LOC644669 0.01636125521 0.033150682545 -5.0166 0.0646 0.0459 0.0718 0.2892 0.0359 0.056622837 COBLL1 COBL-like 1 0.00013056505 0.00043717879 -5.0175 0.3445 0.6459 0.4549 0.3357 0.6696 0.448957554 LRRC7 leucine rich repeat containing 7 0.00038005742 0.001152599032 -5.0203 0.6120 0.3795 0.3987 0.7294 0.6964 0.3246158798 AKAP14 A kinase (PRKA) anchor protein 14 0.01153147025 0.024471895992 -5.0233 0.0623 0.0100 0.1504 0.2391 0.0977 0.147326762 HAVCR1 hepatitis A virus cellular receptor 1 1.04207352E-05 4.35815229E-05 -5.0235 0.1459 0.0763 0.2521 0.4512 0.0828 0.2660644890 MEIG1 meiosis/spermiogenesis associated 1 0.00198292017 0.005143851146 -5.0239 1.6397 2.3020 1.4576 1.4985 3.0734 2.35532257 FGF12 fibroblast growth factor 12 0.01313998518 0.02741422805 -5.0246 0.3894 0.4001 0.5498 0.5999 0.1425 0.3008779 CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.01112350021 0.023691408768 -5.0250 0.0966 0.3658 0.1767 0.1908 0.0787 0.1914253559 CADM2 cell adhesion molecule 2 0.00718405697 0.016147999632 -5.0258 0.5256 0.4205 0.3351 0.6237 0.5546 0.356764066 MMP27 matrix metallopeptidase 27 0.0204726115 0.040257808584 -5.0270 0.0144 0.0149 0.1125 0.2142 0.3157 0.209980144 FRAS1 Fraser syndrome 1 0.00095075593 0.002655083663 -5.0278 0.3834 0.5631 0.4968 0.3893 0.4623 0.40377092 TLL1 tolloid-like 1 0.01311380353 0.027368979805 -5.0283 0.4629 0.8708 0.5951 0.5276 0.4363 0.64681282 COL4A1 collagen, type IV, alpha 1 0.01289400763 0.026956442503 -5.0303 0.3678 1.4698 0.9125 2.2045 0.2683 0.35017169 TPM2 tropomyosin 2 (beta) 2.92275192E-05 0.000111282607 -5.0327 0.8828 1.1298 1.8373 0.8593 0.8732 1.28655570 PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 0.00059693889 0.001733238095 -5.0374 1.2766 1.8533 0.7364 0.7462 0.9249 0.42377068 THRB thyroid hormone receptor, beta 0.00048225613 0.001428397481 -5.0391 0.1586 0.4349 0.3403 0.2274 0.2693 0.138479974 CPED1 hypothetical protein FLJ21986 0.00191142008 0.004975113997 -5.0397 0.4878 0.6363 0.6394 0.3915 0.4273 0.3737387837 CLEC12B C-type lectin domain family 12 member B 0.01197604864 0.025271551083 -5.0406 0.1820 0.0312 0.1369 0.1735 0.1059 0.14172123 EVI2A ecotropic viral integration site 2A 3.89163949E-11 7.67821108E-10 -5.0416 2.8764 3.3476 1.2180 2.8557 2.5424 1.03087754 ZNF204P zinc finger protein 204, pseudogene 2.76371407E-08 2.10459751E-07 -5.0482 2.1298 1.3898 2.2490 1.7205 1.3384 2.1805400823 FAM177B family with sequence similarity 177, member B 0.01436770387 0.029620521853 -5.0483 0.0426 0.1318 0.1855 0.1218 0.1648 0.24397455 ZAN zonadhesin 0.01019279308 0.021985918447 -5.0487 0.1962 0.3342 0.1846 0.2677 0.2020 0.1571100287569 LINC00173 long intergenic non-protein coding RNA 173 0.00145290184 0.003894296965 -5.0533 2.3973 2.0490 1.6387 1.5687 1.6373 1.4685348093 RBPMS2 RNA binding protein with multiple splicing 2 0.00846083175 0.018664290441 -5.0560 1.3790 1.3352 0.7840 0.7587 0.9811 0.62201038 CDR1 cerebellar degeneration-related protein 1, 34kDa 0.00030741672 0.000953670337 -5.0592 0.0370 0.0611 0.0646 0.2292 0.0739 0.24905087 PBX1 pre-B-cell leukemia homeobox 1 0.00039087734 0.001183448346 -5.0613 1.4505 1.1075 0.6304 1.2700 0.5397 0.5561645638 LOC645638 WDNM1-like pseudogene 0.00046338382 0.001376963595 -5.0614 0.2490 0.0850 0.1436 0.2749 0.0350 0.197284708 LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 1.71588322E-07 1.07556152E-06 -5.0644 0.2823 0.3090 0.3279 0.3147 0.2893 0.2229200132 TCTEX1D1 Tctex1 domain containing 1 0.01482286741 0.030431846435 -5.0737 0.8589 1.0708 0.8543 0.7688 0.7785 0.88893568 IL5RA interleukin 5 receptor, alpha 0.00058077174 0.001691672434 -5.0752 0.1270 0.1221 0.1625 0.1983 0.1300 0.1995259283 MDS2 myelodysplastic syndrome 2 translocation associated 1.42728775E-08 1.1742189E-07 -5.0769 1.2774 1.1588 1.0734 1.2877 0.6776 0.68622986 GUCY2F guanylate cyclase 2F, retinal 0.01889532897 0.037570469762 -5.0816 0.4309 0.3576 0.2089 0.4369 0.1267 0.239863950 DMRTA2 DMRT-like family A2 0.01802215451 0.036056148814 -5.0838 0.6340 0.8800 1.1283 0.8159 0.5186 0.9002

932 MS4A3 0.00015679177 0.000515826303 -5.0845 0.1064 0.3435 0.2135 0.1736 0.2030 0.1919338 APOB apolipoprotein B 0.00663677783 0.015071738073 -5.0856 0.4215 0.3832 0.2576 0.4481 0.0973 0.124651454 GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0112374782 0.023914651961 -5.0865 0.1020 0.2684 0.2876 0.1482 0.1384 0.3117400941 LINC00487 long intergenic non-protein coding RNA 487 0.01190462211 0.025141152928 -5.0910 0.0881 0.0222 0.1178 0.2092 0.0359 0.2590129446 XIRP2 xin actin-binding repeat containing 2 0.00161695055 0.004287464874 -5.0911 0.1688 0.1118 0.1443 0.1781 0.2404 0.2069678 ZFP36L2 ZFP36 ring finger protein-like 2 4.20353711E-13 2.35361628E-11 -5.0946 2.8154 0.9598 1.4221 6.4405 3.2414 4.1930643246 MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 1.50908778E-11 3.61567368E-10 -5.1022 1.8165 1.1989 2.1088 1.0419 0.7467 1.41689314 KLF4 Kruppel-like factor 4 (gut) 0.00024361223 0.000771185492 -5.1099 0.5980 2.9635 1.6474 0.5199 2.7055 1.3872645432 ARRDC5 arrestin domain containing 5 6.48775546E-05 0.00023162225 -5.1134 0.2245 0.1249 0.2028 0.1557 0.0436 0.1980729384 TRIM49D2P tripartite motif containing 49D2, pseudogene 0.00529551103 0.012365441208 -5.1136 0.0572 0.0076 0.1132 0.2380 0.0227 0.1183692057 SNORD12 small nucleolar RNA, C/D box 12 0.00263606498 0.006649113653 -5.1171 0.3629 0.9467 1.9588 0.3591 1.0231 1.101123768 FLRT2 fibronectin leucine rich transmembrane protein 2 0.00953424209 0.020741715864 -5.1201 0.3687 0.2241 0.4952 0.5566 0.1369 0.287810913 EDAR ectodysplasin A receptor 2.32857966E-06 1.11997388E-05 -5.1246 1.8040 3.9491 1.6465 2.2045 2.3546 1.29653730 KAL1 Kallmann syndrome 1 sequence 0.00624913932 0.014295908772 -5.1249 0.0767 1.5894 0.5463 0.4178 0.2111 0.771356662 VTRNA1-3 vault RNA 1-3 0.00096136175 0.002681832363 -5.1365 0.5900 0.5784 0.5954 0.6535 1.3896 0.5875693219 MIR634 microRNA 634 0.00709601092 0.015989432923 -5.1383 0.1076 0.0852 0.1221 0.1470 0.0388 0.277659283 CACNG8 calcium channel, voltage-dependent, gamma subunit 8 0.00584388627 0.013472976593 -5.1411 0.0115 0.1274 0.1725 0.2380 0.0478 0.2994163589 TDRD5 tudor domain containing 5 0.01282437978 0.026835440595 -5.1432 0.0666 0.0240 0.1430 0.2403 0.0449 0.2178

3512 IGJ 0.00241256393 0.006139605598 -5.1453 0.1756 0.0485 0.2739 0.1335 0.0174 0.218826053 AUTS2 autism susceptibility candidate 2 4.16738941E-08 3.04099598E-07 -5.1482 1.0683 1.5501 1.3129 0.7169 1.7889 1.0220219539 YPEL4 yippee-like 4 (Drosophila) 0.000570463 0.001664032558 -5.1511 1.0899 2.1999 1.5009 0.7270 1.9477 0.81351511 CTSG cathepsin G 0.00206021531 0.005329782558 -5.1557 0.1587 0.1336 0.1879 0.3400 0.1933 0.3588202500 TCTE1 hypothetical protein MGC33600 0.00352728471 0.00862099333 -5.1578 1.0100 1.1579 0.7367 0.7085 0.5084 0.64605858 PZP pregnancy-zone protein 0.00018701523 0.00060491101 -5.1594 0.0442 0.1080 0.1432 0.2934 0.0976 0.17701803 DPP4 dihydropyrimidine dehydrogenase 7.26872826E-12 2.04329543E-10 -5.1601 1.7306 1.7321 1.7601 1.5284 1.1440 1.720784518 CNFN cornifelin 2.32051053E-06 1.11668076E-05 -5.1621 0.0068 0.3211 0.2165 0.0494 0.0218 0.1902133688 UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 0.00911605356 0.019941162543 -5.1687 0.0768 0.0439 0.1652 0.2580 0.0366 0.1274389730 SPATA31A6 SPATA31 subfamily A, member 6 0.00979441241 0.021247002688 -5.1688 0.0455 0.0920 0.0798 0.4510 0.0429 0.30732668 GDNF glial cell derived neurotrophic factor 0.01515961465 0.031053416906 -5.1720 0.5430 0.3200 0.6123 0.8122 0.1134 0.5166608 TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.00054440824 0.001594394521 -5.1742 0.1911 0.2388 0.3059 0.2173 0.0440 0.206557393 TMEM27 transmembrane protein 27 0.00315190204 0.007802676333 -5.1775 0.0245 0.0968 0.2568 0.2210 0.1038 0.4679100505806 SNHG18 small nucleolar RNA host gene 18 (non-protein coding) 0.00211516828 0.005458036267 -5.1813 0.3406 0.3247 0.1567 0.4163 0.4233 0.18245593 PRKG2 protein kinase, cGMP-dependent, type II 0.00217595058 0.005593552201 -5.1847 0.6094 0.5615 0.7644 0.8545 0.4262 0.56346456 SH3GL2 SH3-domain GRB2-like 2 0.01062478409 0.022777901543 -5.1866 0.2169 0.1748 0.3683 0.4338 0.3066 0.4359285668 C5orf64 hypothetical protein FLJ37543 0.00951025466 0.020703005622 -5.1887 0.0169 0.0663 0.1077 0.0779 0.0113 0.1107100286793 LINC00875 long intergenic non-protein coding RNA 875 3.6739593E-12 1.20090491E-10 -5.1898 2.3842 1.7960 1.6375 3.4018 2.7584 3.3627

93492 TPTE2 0.00605246518 0.013905525437 -5.1924 0.0761 0.0555 0.2003 0.2241 0.0502 0.3361199920 C1orf168 chromosome 1 open reading frame 168 0.01879814587 0.037424245071 -5.1946 0.0629 0.0867 0.1268 0.1026 0.2045 0.2936

643332 ECRP 0.00035274606 0.001077409487 -5.1956 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970100423062 IGLL5 immunoglobulin lambda-like polypeptide 5 0.00124054 0.003378617808 -5.1960 0.0184 0.0191 0.0858 0.0543 0.0269 0.1029100616150 MIR4720 microRNA 4720 0.00103898932 0.002874248725 -5.2030 0.0343 0.0432 0.2259 0.2077 0.0124 0.1084270 AMPD1 adenosine monophosphate deaminase 1 0.00789555236 0.017570031993 -5.2041 0.0438 0.0589 0.1695 0.0455 0.4094 0.153164641 EBF2 early B-cell factor 2 0.01174148101 0.024865593545 -5.2074 0.5270 2.2564 0.8272 0.5517 1.4082 0.61365644 PRSS1 protease, serine, 1 (trypsin 1) 0.00278487937 0.006979195705 -5.2115 0.1036 0.2486 0.4160 0.5057 0.0583 0.376691074 ANKRD30A ankyrin repeat domain 30A 0.01111485709 0.02368128133 -5.2136 0.0043 0.2185 0.1452 0.0583 0.3159 0.1851901 CCNG2 cyclin G2 3.50291749E-11 7.06460357E-10 -5.2155 1.3958 2.4787 1.6288 1.0353 2.4258 2.3919785 CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.00122924487 0.003349852694 -5.2205 1.2160 1.1216 0.8763 0.9237 1.1014 0.610423554 TSPAN12 tetraspanin 12 0.01183217429 0.0250170665 -5.2229 0.4862 1.6236 0.6616 0.4876 0.9989 0.6124343070 PRAMEF9 PRAME family member 9 0.00827061137 0.018297688705 -5.2235 0.0618 0.2908 0.1448 0.1189 0.0293 0.1332

100132708 CYP4F30P cytochrome P450, family 4, subfamily F, polypeptide 30, pseudogene 0.00678962306 0.015388240202 -5.2257 0.0302 0.1717 0.2345 0.2092 0.0183 0.17672543 GAGE1 G antigen 1 0.00529035415 0.012354978405 -5.2272 0.1975 0.1740 0.2302 0.3587 0.2009 0.289529119 CTNNA3 catenin (cadherin-associated protein), alpha 3 0.01056415965 0.022661226232 -5.2309 0.0927 0.0555 0.1563 0.2271 0.0644 0.1668665 BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 4.0318613E-12 1.29606807E-10 -5.2311 1.0776 0.8773 1.5549 0.9560 1.0338 1.742264093 SMOC1 SPARC related modular calcium binding 1 0.00765871182 0.017095038152 -5.2319 0.2929 1.1171 0.4501 0.1782 0.8241 0.462455351 STK32B Q9NY57,serine/threonine kinase 32B 0.00570780786 0.013204996863 -5.2378 2.0248 2.3855 1.2960 1.0371 0.8809 0.8395

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11

membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)

immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides

transmembrane phosphoinositide 3-phosphatase and tensin homolog 2

ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) pseudogene

255101 CCDC108 coiled-coil domain containing 108 0.00567116932 0.013132877464 -5.2482 0.2875 0.4151 0.3321 0.2739 0.2105 0.2780100506123 LOC100506123 uncharacterized LOC100506123 8.15582731E-07 4.33225056E-06 -5.2501 0.0423 0.0723 0.1022 0.5587 0.1099 0.2539200959 GABRR3 gamma-aminobutyric acid (GABA) receptor, rho 3 0.00560272203 0.012986545347 -5.2518 0.1450 0.0233 0.1436 0.2836 0.0316 0.10781462 VCAN versican 0.00081277251 0.002300337561 -5.2573 0.4190 0.2027 0.6328 0.3921 0.1722 0.4362442721 LMOD2 leiomodin 2 (cardiac) 0.00134431391 0.003631864396 -5.2574 0.0616 0.0126 0.1411 0.3024 0.0257 0.10181607 DGKB diacylglycerol kinase, beta 90kDa 0.01160012377 0.024606159913 -5.2638 0.0331 0.0737 0.1684 0.2682 0.0429 0.273710579 TACC2 transforming, acidic coiled-coil containing protein 2 0.00486849536 0.011493171473 -5.2669 0.0805 0.5756 0.3791 0.2887 0.1853 0.30233084 NRG1 neuregulin 1 0.00098908554 0.002750771834 -5.2699 0.2031 0.1790 0.2433 0.2346 0.3410 0.2530133482 SLCO6A1 solute carrier organic anion transporter family, member 6A1 0.02550355567 0.048668508537 -5.2792 0.0794 0.0424 0.1380 0.3369 0.0913 0.1348729396 GAGE12J G antigen 12J 0.000800263 0.002268094548 -5.2806 0.0166 0.0633 0.1488 0.1508 0.0343 0.1755646300 COL6A4P2 similar to alpha 3 type VI collagen isoform 1 precursor 0.00538589841 0.012546039735 -5.2815 0.3128 0.2497 0.2725 0.4238 0.1790 0.338710665 C6orf10 chromosome 6 open reading frame 10 0.01801983261 0.036055451313 -5.2881 0.3111 0.3101 0.3304 0.3790 0.3671 0.37961287 COL4A5 collagen, type IV, alpha 5 0.011880795 0.025105341312 -5.2940 2.8120 0.8953 0.1483 2.1250 0.3132 0.18394626 MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 0.00703359454 0.015860525662 -5.2942 0.0217 0.0167 0.2571 0.1478 0.0409 0.110190527 DUOXA1 dual oxidase maturation factor 1 0.00352434909 0.008616123442 -5.2955 1.7945 0.0922 0.6047 2.2390 0.1411 0.223822915 MMRN1 multimerin 1 6.6245221E-06 2.89438708E-05 -5.2979 2.2075 0.6697 0.8981 1.1969 0.3621 0.525223581 CASP14 caspase 14, apoptosis-related cysteine peptidase 0.02189977005 0.042674384842 -5.3019 0.0680 0.0384 0.3480 0.1000 0.0483 0.2608389493 NUPR1L nuclear protein, transcriptional regulator, 1-like 0.00046663536 0.001385949483 -5.3031 0.3321 0.3321 0.3321 0.3970 0.3970 0.397029949 IL19 interleukin 19 0.00566461986 0.013121695491 -5.3046 0.6192 0.6326 0.6204 0.4296 0.2519 0.396911199 ANXA10 annexin A10 0.01255460941 0.02634939388 -5.3084 0.0328 0.0288 0.1126 0.1824 0.0197 0.15128406 SRPX sushi-repeat containing protein, X-linked 0.0004242432 0.001272033427 -5.3105 0.5513 0.4723 0.8697 0.3057 0.5941 0.58012890 GRIA1 glutamate receptor, ionotropic, AMPA 1 0.00929465258 0.020290548625 -5.3107 0.0548 0.0328 0.1694 0.2021 0.4620 0.1702219770 GJD4 connexin40.1 0.01245030341 0.026148499306 -5.3119 0.0320 0.0376 0.3310 0.2246 0.0240 0.20941843 DUSP1 dual specificity phosphatase 2 1.29487659E-10 2.04848356E-09 -5.3121 1.9185 1.9066 2.5374 1.8835 2.0363 2.61682259 FGF14 fibroblast growth factor 14 0.01093463081 0.023349021178 -5.3148 0.6013 1.2249 0.8693 0.6034 0.5834 0.605054933 RHBDL2 rhomboid, veinlet-like 2 (Drosophila) 0.00597664608 0.01374688785 -5.3165 0.1206 0.1294 0.1725 0.1611 0.0469 0.2288619564 SNORD72 small nucleolar RNA, C/D box 72 0.00780956954 0.017395642392 -5.3190 1.1148 2.3726 1.6116 1.0563 1.3732 0.848680108 ZFP2 ZFP2 zinc finger protein 1.03625197E-05 4.33777684E-05 -5.3192 0.5425 0.4726 1.0814 0.5246 0.5177 1.39989450 LY86 lymphocyte antigen 86 0.00088641985 0.002491794386 -5.3209 1.0390 1.2114 1.2244 0.7946 0.8251 0.7125116328 C8orf34 chromosome 8 open reading frame 34 0.00957672368 0.020819261752 -5.3267 0.0940 0.0265 0.1373 0.2597 0.0572 0.19587852 CXCR4 chemokine (C-X-C motif) receptor 4 1.05552026E-10 1.74162334E-09 -5.3300 2.9834 2.7718 1.9195 3.7343 2.6485 2.5152692197 SNORD77 small nucleolar RNA, C/D box 77 0.00403951719 0.00973687967 -5.3331 0.3321 0.3321 0.3321 0.3970 0.3970 0.39703892 KRT86 keratin 86 0.00218982511 0.005624716426 -5.3359 0.0703 0.0670 0.2147 0.1193 0.0553 0.3580202309 GAPT chromosome 5 open reading frame 29 0.00066489914 0.001909925643 -5.3378 0.4903 0.3291 0.1992 0.4534 0.2342 0.1914153579 BTNL9 butyrophilin-like 9 0.00260990875 0.006589889979 -5.3380 0.0227 0.0217 0.1638 0.0685 0.0394 0.333779971 WLS wntless homolog (Drosophila) 0.00918437395 0.02007859307 -5.3387 0.4161 1.1375 0.3282 0.4980 1.0498 0.217156159 TEX11 testis expressed 11 0.01162206738 0.024644123844 -5.3417 0.0292 0.0907 0.0712 0.1753 0.0296 0.125611345 GABARAPL2 GABA(A) receptor-associated protein-like 2 5.31620758E-16 3.08000989E-13 -5.3433 2.2615 3.3078 1.9150 2.4524 3.1945 2.2100341640 FREM2 FRAS1 related extracellular matrix protein 2 0.0041961584 0.01007783995 -5.3474 0.4896 0.2553 0.4308 1.0804 0.1909 0.377427255 CNTN6 contactin 6 0.0093346324 0.020358367538 -5.3587 0.0705 0.0285 0.1669 0.4863 0.0363 0.1427255324 EPGN epithelial mitogen homolog (mouse) 0.00063973345 0.001844305711 -5.3611 1.5148 0.6562 0.4366 0.7490 0.3367 0.2018

9223 MAGI1 0.00058298757 0.001697585488 -5.3625 0.3642 0.6500 0.7288 0.4402 1.3348 0.6694152578 LOC152578 uncharacterized LOC152578 0.01045023579 0.022456392848 -5.3788 0.0605 0.0735 0.1480 0.3750 0.0221 0.20097365 UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 0.01043945795 0.022443790521 -5.3831 0.1910 0.2098 0.2241 0.3654 0.2221 0.256127443 CECR2 cat eye syndrome chromosome region, candidate 2 0.00238497672 0.006072783544 -5.3851 0.0531 0.0665 0.1905 0.1498 0.0665 0.1750100507424 LOC100507424 uncharacterized LOC100507424 4.13388458E-09 4.00712674E-08 -5.3860 0.2024 0.0459 0.1605 0.1887 0.0344 0.24025005 ORM2 orosomucoid 2 4.39114581E-05 0.000162058203 -5.3865 0.1285 0.7211 0.2264 0.2774 0.0467 0.210064591 TSPY2 testis specific protein, Y-linked 2 0.00857418157 0.018884696916 -5.3883 0.0339 0.1673 0.4931 0.5647 0.2022 0.1597259232 NALCN sodium leak channel, non-selective 0.01256967773 0.026377989136 -5.3883 0.4678 0.8235 0.3552 0.5268 0.2221 0.276026047 CNTNAP2 contactin associated protein-like 2 0.00481500651 0.011387328713 -5.3887 0.6696 0.9778 0.5110 0.4810 0.5231 0.3720139420 SMEK3P SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene 0.01073428283 0.022982987558 -5.3900 0.0610 0.0164 0.0198 0.0946 0.0163 0.080184467 FBN3 fibrillin 3 0.0040314589 0.009723180713 -5.3989 0.0687 0.0533 0.2816 0.1872 0.0533 0.2784653643 GOLGA6D golgin A6 family, member D 0.00057397579 0.001672943942 -5.4027 0.0331 0.0455 0.1606 0.1320 0.0227 0.22579568 GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.00998468838 0.021600784521 -5.4047 0.2354 0.2230 0.3848 0.1177 0.1602 0.3697374470 C12orf42 chromosome 12 open reading frame 42 1.4434466E-06 7.26774767E-06 -5.4053 2.2911 1.8695 1.2854 1.6295 1.1993 1.07719758 FRMPD4 FERM and PDZ domain containing 4 0.00616427828 0.014121576311 -5.4066 0.2200 0.1075 0.3230 0.2149 0.1942 0.2113401232 LINC01011 long intergenic non-protein coding RNA 1011 3.7632701E-08 2.76710146E-07 -5.4080 3.4811 6.9111 1.7245 3.2101 2.7872 3.1171168544 ZNF467 zinc finger protein 467 5.57969555E-06 2.47637107E-05 -5.4090 1.0553 3.0886 1.0877 0.9304 1.9364 1.5185727830 SPATA31A3 SPATA31 subfamily A, member 3 0.0050387886 0.011853836151 -5.4125 0.0467 0.2434 0.1581 0.2114 0.8439 0.36799378 NRXN1 neurexin 1 0.00318116545 0.0078634003 -5.4136 0.2304 0.2562 0.2551 0.4137 0.2241 0.3888728403 TSPY8 testis specific protein, Y-linked 8 0.00764430667 0.017067054179 -5.4173 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970401535 C9orf170 FLJ45537 protein 0.01208336397 0.025477408997 -5.4198 0.2455 0.0686 0.4634 0.5871 0.1079 0.37496953 TCP10 t-complex 10 0.01114070651 0.023722525275 -5.4243 0.0275 0.0156 0.0701 0.1300 0.0218 0.260722999 RIMS1 regulating synaptic membrane exocytosis 1 0.00582132824 0.013426825256 -5.4257 0.0726 0.1252 0.1380 0.2649 0.1046 0.1718100616498 MIR378E microRNA 378e 0.00449437505 0.010706808465 -5.4278 0.0368 0.0287 0.0802 0.1047 0.0221 0.175427284 SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 2.64595874E-07 1.58151646E-06 -5.4344 3.7281 3.5894 2.1209 3.5760 2.8692 1.1911145624 PWAR1 Prader Willi/Angelman region RNA 1 0.00641456037 0.014639875982 -5.4349 0.1207 0.1570 0.0856 0.3914 0.1682 0.18145139 PDE3A phosphodiesterase 3A, cGMP-inhibited 0.00207708306 0.005368858627 -5.4372 0.2294 0.1994 0.2790 0.2675 0.1721 0.375157578 UNC79 unc-79 homolog (C. elegans) 0.00140609016 0.00377991458 -5.4421 0.7251 0.2348 0.2618 0.5016 0.1810 0.448426184 OR1F2P olfactory receptor, family 1, subfamily F, member 2 0.00524367631 0.012264436715 -5.4429 1.7971 0.8668 2.5834 1.2147 0.4509 1.11641117 CHI3L2 chitinase 3-like 2 1.10166698E-06 5.68795111E-06 -5.4449 1.5483 1.4852 1.8279 1.2019 0.9429 0.792226817 SNORD34 small nucleolar RNA, C/D box 34 0.00493369009 0.011626049168 -5.4468 0.3321 0.3321 0.3321 0.3970 0.3970 0.397079366 HMGN5 high mobility group nucleosome binding domain 5 7.48223791E-09 6.62381062E-08 -5.4497 0.3321 0.3321 0.3321 0.3970 0.3970 0.397026795 SNORD54 small nucleolar RNA, C/D box 54 0.01170820899 0.024805337677 -5.4559 2.7319 3.0544 1.5076 1.8807 2.0098 1.102826806 SNORD44 small nucleolar RNA, C/D box 44 0.00815960524 0.018095922672 -5.4561 0.3321 0.3321 0.3321 0.3970 0.3970 0.39707098 TLR3 toll-like receptor 3 0.00024126716 0.000764424052 -5.4577 0.8673 0.8652 0.7243 0.6137 0.7774 0.4508643432 TSG1 tumor suppressor TSG1 0.00653009381 0.014870123883 -5.4608 0.0326 0.0329 0.1371 0.2917 0.0317 0.26585649 RELN reelin 0.00580088082 0.013393188566 -5.4668 0.3903 0.5559 1.0162 0.4917 0.2822 0.4909

121456 SLC9A7P1 0.0062321649 0.014264576854 -5.4734 0.4130 0.3561 1.1347 0.3890 0.2518 0.6984158381 ATP8B5P hypothetical protein LOC158381 1.61701672E-08 1.31141276E-07 -5.4743 0.2880 0.3971 0.4084 0.5468 0.5141 0.354310151 HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 1.27279339E-07 8.21493493E-07 -5.4760 0.0633 0.0391 0.1832 0.5125 0.0382 0.29356708 SPTA1 spectrin, alpha, erythrocytic 1 (elliptocytosis 2) 0.00312101354 0.007732496178 -5.4760 0.1359 0.1256 0.2199 0.1306 0.0152 0.156026034 IPCEF1 interaction protein for cytohesin exchange factors 1 1.25619629E-10 2.00640023E-09 -5.4843 0.2991 0.2910 0.4587 0.3920 0.1831 0.3361283310 OTOGL chromosome 12 open reading frame 64 0.00582525541 0.013434187403 -5.4886 0.0859 0.0182 0.1034 0.3249 0.0275 0.163659084 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 3.80262254E-07 2.1883943E-06 -5.4905 0.9881 1.4169 0.9631 0.7469 1.4366 0.734256112 PCDHGA3 protocadherin gamma subfamily A, 3 0.00693439079 0.015658080627 -5.4909 0.2053 0.6208 0.2971 1.2274 0.3705 0.54791052 CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.00010197477 0.000349978026 -5.4970 0.6328 3.1675 1.4501 0.4237 2.8794 1.13255340 PLG plasminogen 0.0043113663 0.010316564297 -5.5063 0.0207 0.0069 0.0937 0.1797 0.0346 0.129389866 SEC16B SEC16 homolog B (S. cerevisiae) 0.00547169952 0.012719961012 -5.5189 0.1103 0.0906 0.1530 0.3147 0.0945 0.190023284 LPHN3 latrophilin 3 0.00645465604 0.014720353855 -5.5196 0.0894 0.0705 0.1598 0.3273 0.0657 0.1906574 BAGE B melanoma antigen 0.00821015164 0.018192564971 -5.5244 0.1967 0.1749 0.1985 0.3733 0.2511 0.27002495 FTH1 ferritin, heavy polypeptide 1 8.50021108E-10 1.02057563E-08 -5.5257 1.1382 2.5723 1.9333 1.3816 3.5322 3.16308875 VNN2 vanin 2 7.85830974E-09 6.89659153E-08 -5.5258 1.5100 0.6209 0.9341 1.1096 0.4002 0.48705314 PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.00178263013 0.004670521602 -5.5315 0.0552 0.0545 0.1317 0.2543 0.2554 0.1802404550 C16orf74 chromosome 16 open reading frame 74 3.32884131E-07 1.94452009E-06 -5.5342 0.6060 0.8596 1.2585 0.5127 0.7072 0.689457484 RNF150 ring finger protein 150 0.01191718584 0.025158962414 -5.5410 0.6987 1.8569 1.0472 0.5782 1.3907 1.17045996 RGS1 regulator of G-protein signaling 1 2.67743828E-07 1.59771888E-06 -5.5421 1.3685 2.5777 1.1827 1.2194 1.5026 0.6906139065 SLITRK4 SLIT and NTRK-like family, member 4 0.00339768207 0.008334333028 -5.5476 0.0563 0.2914 0.2012 0.2070 0.3092 0.3174730971 FLJ36777 uncharacterized LOC730971 0.00020904463 0.000669529103 -5.5479 1.9048 1.8280 2.0172 1.1764 1.3193 1.69247140 TNNT3 troponin T type 3 (skeletal, fast) 0.00017172864 0.000559426943 -5.5497 0.0498 0.1278 0.1198 0.0809 0.0397 0.171610161 LPAR6 lysophosphatidic acid receptor 6 4.66336697E-08 3.35204726E-07 -5.5524 1.2662 0.7996 0.6912 1.4286 0.4564 0.639983889 WDR87 WD repeat domain 87 0.01087035366 0.023230772164 -5.5545 0.2990 0.2463 0.3524 0.2000 0.1906 0.48937380 UPK3A uroplakin 3A 0.00022734358 0.000722941501 -5.5676 0.6724 0.8351 0.8087 0.3633 0.5787 0.40776332 SCN7A sodium channel, voltage-gated, type VII, alpha subunit 0.00447905211 0.01067448026 -5.5689 0.0570 0.1832 0.1352 0.2554 0.0324 0.1926460 ASTN1 astrotactin 1 0.00486026716 0.011475229568 -5.5718 0.0682 0.2218 0.1501 0.1280 0.4736 0.2339

100499405 LINC00987 2.89982172E-10 4.13303764E-09 -5.5731 1.3196 0.5798 1.8457 1.2626 0.8355 1.337127445 PCLO piccolo presynaptic cytomatrix protein 0.00233295271 0.005954422662 -5.5733 0.2126 0.5367 0.4347 0.3847 0.3915 0.409864174 DPEP2 dipeptidase 2 2.33935881E-07 1.41726672E-06 -5.5796 1.4071 1.4929 1.8942 1.0603 1.0325 1.063580258 EFHC2 EF-hand domain (C-terminal) containing 2 6.26476575E-06 2.74705543E-05 -5.5807 0.9571 1.3728 0.7818 1.3591 1.7719 0.7436100128071 FAM229A family with sequence similarity 229, member A 3.71130047E-07 2.14529839E-06 -5.5831 0.3926 0.3318 1.7800 1.3434 0.4772 0.4156100616408 MIR5047 microRNA 5047,microRNA 5047 1.07291987E-07 7.05447711E-07 -5.5852 0.4368 0.9454 0.5899 0.5452 0.9192 0.5362644945 KRT16P3 keratin 16 pseudogene 3 0.01180563366 0.024975400982 -5.5866 0.0598 0.0246 0.1138 0.1816 0.0214 0.2201100750225 PCAT1 prostate cancer associated transcript 1 (non-protein coding) 6.18012138E-05 0.000221591793 -5.5876 0.1144 0.0240 0.2508 0.3373 0.0217 0.3542219681 ARMC3 armadillo repeat containing 3 0.00595528973 0.013708119661 -5.5950 0.9204 0.5696 0.7714 0.6167 0.5197 0.504726819 SNORD32A small nucleolar RNA, C/D box 32A 0.00272059504 0.006834966664 -5.5951 2.3608 3.9704 1.5819 1.0480 7.8200 1.1162160364 CLEC12A C-type lectin domain family 12, member A 0.00034716111 0.001063246378 -5.5981 0.7613 0.9433 0.6432 0.3264 0.3873 0.2845116362 RBP7 retinol binding protein 7, cellular 0.00220109575 0.005648654716 -5.6105 1.2610 0.7506 0.8941 0.8310 0.3729 0.7136619570 SNORD95 small nucleolar RNA, C/D box 95 0.00195839773 0.00508509924 -5.6177 0.3321 0.3321 0.3321 0.3970 0.3970 0.397026820 SNORD24 small nucleolar RNA, C/D box 24 0.00661932335 0.015036255911 -5.6184 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970114788 CSMD3 CUB and Sushi multiple domains 3 0.00159545119 0.00423660574 -5.6201 0.0857 0.0738 0.1704 0.3708 0.1300 0.1362374454 KRT77 keratin 77 0.00777526576 0.017330539922 -5.6230 0.0687 0.1230 0.1623 0.2202 0.0522 0.1811727677 CASC8 hypothetical protein LOC727677 0.00542956565 0.012636482434 -5.6255 0.1217 0.0757 0.1154 0.1602 0.3092 0.31207258 TSPY1 testis specific protein, Y-linked 1 0.00392465174 0.009483104537 -5.6262 0.0219 0.0151 0.2665 1.0424 0.0087 0.312011122 PTPRT protein tyrosine phosphatase, receptor type, T 0.0041730208 0.01002754288 -5.6445 0.0677 0.0540 0.1566 0.2528 0.1318 0.1840442524 DPY19L2P3 dpy-19-like 2 pseudogene 3 (C. elegans) 0.00288535698 0.007204323964 -5.6470 1.3750 1.1299 2.1506 0.8733 1.0484 1.4194283420 CLEC9A C-type lectin domain family 9, member A 4.86892241E-05 0.000178001101 -5.6485 0.0609 0.0924 0.1216 0.1995 0.3217 0.1293149699 GTSF1L gametocyte specific factor 1-like 0.00249292103 0.006321211916 -5.6519 0.4208 0.2503 0.2806 0.4489 0.2173 0.3143254827 NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.00423196851 0.010151835176 -5.6553 0.0372 0.0254 0.1161 0.2242 0.0694 0.1533100422879 MIR3124 microRNA 3124 0.00380678514 0.009221932134 -5.6668 1.1368 3.1626 1.6704 0.7005 1.8559 1.264754715 RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.00702954152 0.015853342701 -5.6699 0.0322 0.0457 0.1354 0.2766 0.0601 0.19289699 RIMS2 regulating synaptic membrane exocytosis 2 0.00266063926 0.006705544901 -5.6763 0.3255 0.7532 0.5179 0.3101 0.7921 0.549850852 TRAT1 T cell receptor associated transmembrane adaptor 1 2.94530463E-13 1.80592639E-11 -5.6770 2.3375 4.4368 1.4539 1.8426 3.7707 1.3380

201780 SLC10A4 0.00449407876 0.010706808465 -5.6775 0.6485 1.8598 1.2338 0.6627 1.2236 1.051454360 CYTL1 cytokine-like 1 0.00047778013 0.001416260068 -5.6817 0.3940 0.6016 0.3734 0.2287 0.2279 0.17646279 S100A8 S100 calcium binding protein A8 0.00044373891 0.001324187052 -5.6900 0.0523 0.0558 0.1159 0.3103 0.0412 0.2971140453 MUC17 mucin 17, cell surface associated 0.00211729742 0.005462758892 -5.6959 0.1163 0.2500 0.3242 0.1630 0.0864 0.145654549 SDK2 sidekick cell adhesion molecule 2 3.31774602E-06 1.54371926E-05 -5.6968 0.6662 1.1244 1.0754 0.5262 0.9225 0.9650100126348 MIR760 microRNA 760 0.00340300733 0.008346275155 -5.6971 2.8950 4.6494 1.3993 1.6207 2.6211 1.621322895 RPH3A rabphilin 3A homolog (mouse) 0.00068275776 0.001955997148 -5.6985 0.1301 0.0305 0.1455 0.1789 0.0843 0.256079852 EPHX3 epoxide hydrolase 3 0.0022569139 0.005777294873 -5.7077 0.7385 0.7859 0.7343 0.4125 1.1973 0.4237

membrane associated guanylate kinase, WW and PDZ domain containing 1

solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 pseudogene 1

long intergenic non-protein coding RNA 987,long intergenic non-protein coding RNA 987

solute carrier family 10 (sodium/bile acid cotransporter family), member 4

10875 FGL2 fibrinogen-like 2 0.00014803809 0.000489495488 -5.7099 2.4377 1.9875 1.2412 1.5545 1.4476 0.89423083 HGFAC HGF activator 0.00533604109 0.012448945708 -5.7119 0.0640 0.0390 0.1891 0.1752 0.1078 0.20743858 KRT10 keratin 10 2.35521551E-15 6.72414028E-13 -5.7189 0.1631 0.1746 0.2546 0.2004 0.1801 0.24899480 ONECUT2 one cut homeobox 2 0.00172251304 0.004531858636 -5.7221 2.5200 2.3762 1.3193 1.6735 1.2688 0.78413176 HNMT histamine N-methyltransferase 0.00353188091 0.008628764267 -5.7230 0.2175 0.3552 0.3423 0.2852 0.1183 0.2080729447 GAGE2A G antigen 2A 0.00103270513 0.002858595396 -5.7231 0.3321 0.3321 0.3321 0.3970 0.3970 0.397022871 NLGN1 neuroligin 1 0.00574103359 0.013273461447 -5.7265 0.2769 0.7339 0.2920 0.4917 0.3611 0.2448146862 UNC45B unc-45 homolog B (C. elegans) 0.00030855077 0.000955890069 -5.7344 0.1608 0.0983 0.2706 0.2028 0.0730 0.3569254158 CXorf58 chromosome X open reading frame 58 0.00360805655 0.008792532586 -5.7370 0.0651 5.5170 4.7503 0.1254 0.4445 1.2542153222 CREBRF adult retina protein 8.75540519E-14 7.3384754E-12 -5.7429 1.8803 1.9214 2.3411 1.7524 2.4501 2.50522354 FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.00031522E-07 6.61997816E-07 -5.7462 1.9993 1.6620 2.2177 1.8123 2.0125 2.0476130 ADH6 alcohol dehydrogenase 6 (class V) 0.00379732425 0.00920465756 -5.7616 0.0591 0.1258 0.2253 0.1790 0.0243 0.304955553 SOX6 SRY (sex determining region Y)-box 6 0.0009907264 0.002754496772 -5.7676 7.1375 3.4775 1.2413 6.0549 4.9870 1.05683048 HBG2 hemoglobin, gamma G 0.02499879198 0.047870250157 -5.7758 0.1000 0.0576 0.1716 0.3002 0.0963 0.2338340547 VSIG1 V-set and immunoglobulin domain containing 1 1.64412238E-07 1.03591049E-06 -5.7795 0.2244 0.4156 0.3458 0.3463 0.2241 0.41893848 KRT1 keratin 1 4.64644636E-05 0.000170550156 -5.7825 0.9584 0.7357 0.3781 0.7267 0.3118 0.1381150622 LOC150622 uncharacterized LOC150622 0.00314382526 0.007784296294 -5.7914 0.0269 0.0396 0.0479 0.0884 0.0343 0.1719120114 FAT3 FAT atypical cadherin 3 0.00198759349 0.005154315674 -5.7916 0.0317 0.0441 0.1307 0.2948 0.0162 0.1474114780 PKD1L2 polycystic kidney disease 1-like 2 0.00255212681 0.006459684309 -5.7920 0.0617 0.0285 0.1453 0.1468 0.0384 0.16574988 OPRM1 opioid receptor, mu 1 0.00375808141 0.009125270896 -5.7924 0.0602 0.0468 0.1215 0.1963 0.0734 0.1917433 ASGR2 asialoglycoprotein receptor 2 0.00232552988 0.005938795511 -5.7931 0.0978 0.2034 0.3004 0.0800 0.1651 0.12213820 KLRB1 killer cell lectin-like receptor subfamily B, member 1 7.28979944E-06 3.15488431E-05 -5.7937 0.7028 0.8470 0.3832 0.6434 0.2573 0.3173100616323 MIR4482-1 microRNA 4482-1 0.00216489806 0.00556984193 -5.7959 1.3799 0.4180 1.5182 0.9853 0.8034 0.901079722 ANKRD55 ankyrin repeat domain 55 2.23253692E-11 4.96868631E-10 -5.7960 0.6259 0.4038 0.5464 0.4345 0.1551 0.4263114784 CSMD2 CUB and Sushi multiple domains 2 0.00110681003 0.003047563712 -5.7986 0.1435 0.1663 0.2404 0.2662 0.7199 0.237310628 TXNIP thioredoxin interacting protein 6.78266652E-11 1.20674667E-09 -5.8018 2.9556 3.1165 2.2938 4.6441 4.9091 2.491479750 ZNF385D zinc finger protein 385D 3.77357023E-07 2.17647333E-06 -5.8125 0.0850 0.1862 0.4261 0.1361 0.1621 0.1815142685 ASB15 ankyrin repeat and SOCS box-containing 15 2.54329925E-05 9.79371208E-05 -5.8139 0.0832 0.0275 0.1069 0.2294 0.0505 0.119810223 GPA33 glycoprotein A33 (transmembrane) 1.32369182E-08 1.09739096E-07 -5.8290 1.9741 1.3752 1.4346 1.6113 0.7206 0.4718441461 LOC441461 uncharacterized LOC441461 7.6689488E-05 0.000270515507 -5.8295 0.3615 0.3083 0.3215 0.3530 1.4871 0.37222219 FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00036003099 0.001097878216 -5.8331 0.1102 0.3803 0.1152 0.0581 0.2240 0.1839406888 MIRLET7F1 microRNA let-7f-1 0.00409840782 0.009863574873 -5.8336 0.2866 0.6109 0.9711 0.2257 0.2537 0.539129760 BLNK B-cell linker 0.00076746656 0.002183270913 -5.8416 0.1612 0.1406 0.2530 0.2352 0.2057 0.1971257101 ZNF683 zinc finger protein 683 2.87383234E-06 1.35336764E-05 -5.8448 1.0826 0.9016 0.9975 0.3579 0.6108 0.4707283659 PRTG protogenin homolog (Gallus gallus) 0.00137706402 0.00370788592 -5.8475 0.6077 1.0557 0.6309 0.4896 0.6142 0.4965642629 SPATA31A4 SPATA31 subfamily A, member 4 0.00211804284 0.005463910598 -5.8556 0.0999 0.0078 0.2108 0.5055 0.1620 0.114279148 MMP28 matrix metallopeptidase 28 2.0600227E-06 1.0026834E-05 -5.8646 1.3983 1.0696 1.1535 0.9646 0.8746 0.941884460 ZMAT1 zinc finger, matrin-type 1 2.13979429E-10 3.1632946E-09 -5.8650 0.9196 0.6348 0.8475 1.1541 1.1616 1.0045

7020 TFAP2A 0.00089129358 0.002504338968 -5.8776 0.2357 0.3867 0.3793 0.2699 0.2544 0.440810100 TSPAN2 tetraspanin 2 2.07622995E-08 1.63893798E-07 -5.8787 1.4714 2.1901 1.2628 0.9036 2.8186 1.0489100616364 MIR4785 microRNA 4785 0.00128925034 0.003497725653 -5.8821 0.9445 2.4209 1.3572 1.2129 2.6673 1.9820339896 GADL1 glutamate decarboxylase-like 1 0.00225922233 0.005782393963 -5.8846 0.8214 0.9347 0.8424 0.5047 0.9805 0.6508692109 SNORD69 small nucleolar RNA, C/D box 69 0.00137276653 0.00369794929 -5.8848 0.2458 0.5586 0.5862 0.4115 0.4086 0.41328735 MYH13 myosin, heavy chain 13, skeletal muscle 0.00223224352 0.005720554498 -5.8873 0.0579 0.0333 0.1427 0.1875 0.0097 0.1932347127 SPATA31D5P SPATA31 subfamily D, member 5, pseudogene 0.00361335976 0.00880428185 -5.8916 0.0355 0.0044 0.0907 0.4363 0.0012 0.245326154 ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.000746175 0.002126011175 -5.9063 0.0707 0.0165 0.0867 0.1357 0.0186 0.1031285359 PDCL3P4 phosducin-like 3 pseudogene 2.26062058E-07 1.3741204E-06 -5.9121 0.2373 0.1701 0.2340 0.5192 0.1168 0.3669

25769 SLC24A2 0.0009003054 0.002528105169 -5.9229 0.0387 0.0985 0.1085 0.1082 0.0244 0.1596221981 THSD7A thrombospondin, type I, domain containing 7A 0.00496434964 0.011690758693 -5.9292 0.1718 0.1763 0.4262 0.3430 0.4162 0.372051314 NME8 NME/NM23 family member 8 0.00099140881 0.002755974712 -5.9308 0.0424 0.0166 0.1650 0.2134 0.0251 0.2361140807 KRT72 keratin 72 1.80611853E-06 8.91447806E-06 -5.9520 0.7786 0.6938 0.3309 0.6817 0.1967 0.2812359822 KCNIP4-IT1 KCNIP4 intronic transcript 1 (non-protein coding) 0.00256909164 0.006498123259 -5.9623 0.0365 0.0020 0.0981 0.1463 0.0196 0.1622254958 REXO1L1 REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1 0.00079740219 0.002260687792 -5.9624 0.0375 0.0566 0.1665 0.2146 0.1501 0.223523495 TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 9.68933122E-05 0.000333792346 -5.9736 0.0644 0.2540 0.2608 0.1075 0.1300 0.2139440279 UNC13C unc-13 homolog C (C. elegans) 0.00093525879 0.002616204634 -5.9750 0.0902 0.0654 0.0810 0.3001 0.0387 0.124894025 MUC16 mucin 16, cell surface associated 0.00070397278 0.002014248444 -5.9752 0.0892 0.0291 0.1805 0.1757 0.1809 0.2070375719 AQP7P1 aquaporin 7 pseudogene 1 0.00054566843 0.001597061275 -5.9834 0.0636 0.0543 0.2268 0.1837 0.0999 0.2411167838 TXLNB taxilin beta 2.57586794E-06 1.22568383E-05 -5.9845 2.2215 1.4439 1.8788 1.3772 0.9849 1.00591823 DSC1 desmocollin 3 2.35795028E-06 1.13290738E-05 -5.9976 1.2697 2.4037 0.5600 0.9962 2.2285 0.406781793 TLR10 toll-like receptor 10 0.00027648422 0.000865054748 -6.0033 0.4658 0.3749 0.4285 0.1803 0.0957 0.1893406942 MIR150 microRNA 150 0.00154941608 0.004126356317 -6.0055 2.3088 1.8726 2.3607 2.2563 1.4828 1.7605727832 GOLGA6L6 golgin A6 family-like 6 0.00444483279 0.010601665881 -6.0110 0.0493 0.0523 0.1779 0.3202 0.1234 0.16741755 DMBT1 deleted in malignant brain tumors 1 0.00171584205 0.004516258423 -6.0115 0.0551 0.0875 0.1388 0.2278 0.0589 0.17551755 DMBT1 dystrophia myotonica, WD repeat containing 0.00171584205 0.004516258423 -6.0115 0.0551 0.0875 0.1388 0.2278 0.0589 0.175526770 SNORD79 small nucleolar RNA, C/D box 79 0.0004510087 0.001343686782 -6.0129 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706083 SNORD21 small nucleolar RNA, C/D box 21 8.99670382E-05 0.000312168197 -6.0165 0.7641 1.0518 0.7084 0.3254 0.7305 0.51631832 DSP solute carrier family 26 (anion exchanger), member 2 0.00018172081 0.000589141717 -6.0241 1.9592 2.3002 1.7185 1.6467 1.1621 1.3381100463482 MTRNR2L6 MT-RNR2-like 6 0.00272754945 0.006848671632 -6.0271 0.1084 0.1611 0.1712 0.1423 0.1718 0.316855889 GOLGA6B golgin A6 family, member B 0.00021905257 0.000698643487 -6.0319 0.0440 0.1464 0.2462 0.2448 0.0454 0.2031342096 GOLGA6A golgin A6 family, member A 2.51984433E-05 9.71772807E-05 -6.0431 0.0814 0.0574 0.1823 0.3590 0.0196 0.2181100302170 MIR1206 microRNA 1206 1.41902208E-05 5.76698654E-05 -6.0505 0.6131 1.9311 1.4798 0.4263 1.2504 0.6534692085 SNORD45C small nucleolar RNA, C/D box 45C 7.32604555E-05 0.000259070068 -6.0540 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970131831 FAM194A family with sequence similarity 194, member A 8.92666026E-08 5.99000868E-07 -6.0584 2.2203 1.9856 2.1170 2.1223 1.8565 2.39937225 TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.0040110064 0.009677685057 -6.0627 0.1288 0.3000 0.1259 0.3249 0.0796 0.1316153643 FAM81B family with sequence similarity 81, member B 0.00018072134 0.000586213457 -6.0866 0.0484 0.0290 0.0731 0.1301 0.0416 0.1799114907 FBXO32 F-box protein 32 1.5622343E-12 6.12556763E-11 -6.0925 0.9336 1.4211 1.3562 0.7126 1.1341 1.4203642569 TRIM53AP tripartite motif containing 53A, pseudogene 0.00294047204 0.007329918835 -6.0959 0.0400 0.1920 0.0430 0.2001 0.0101 0.123893035 PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 0.00018922391 0.000611405714 -6.1147 0.1603 0.0941 0.2269 0.2585 0.1340 0.2171728395 TSPY4 testis specific protein, Y-linked 4 0.0015636342 0.004161189072 -6.1217 0.6234 0.1900 0.2361 11.0201 0.6100 0.3349

267020 ATP5L2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G2 5.0452746E-06 2.26115422E-05 -6.1241 0.1327 0.1280 0.1952 0.1846 0.0593 0.25336581 SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.00062473611 0.001806484907 -6.1337 0.2976 0.6881 0.6758 0.4933 0.2593 0.70992195 FAT1 FAT atypical cadherin 1 0.00048165256 0.001427072413 -6.1420 0.2701 0.3924 0.4167 0.3333 0.5616 0.337956344 CABP5 calcium binding protein 5 3.10462299E-05 0.000117594675 -6.1440 0.0507 0.0200 0.3909 0.3026 0.0139 0.27514353 MPO myeloperoxidase 1.2396983E-05 5.10519886E-05 -6.1482 0.1572 0.1559 0.1973 0.1020 0.2024 0.2449619571 SNORD96A small nucleolar RNA, C/D box 96A 0.00090234731 0.002533449614 -6.1528 0.7183 2.0252 2.2238 0.4366 1.3804 1.7981653641 GOLGA6C golgin A6 family, member C 1.49209355E-05 6.03442525E-05 -6.1535 0.0469 0.0889 0.1996 0.2204 0.0531 0.2436122706 PSMB11 proteasome (prosome, macropain) subunit, beta type, 11 0.00222234029 0.005699172176 -6.1548 0.0409 0.0195 0.0933 0.2096 0.0449 0.138055799 CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta 3 subunit 0.00020434886 0.000655869035 -6.1572 0.0806 0.0726 0.2337 0.2361 0.0325 0.2526100033414 SNORD116-2 small nucleolar RNA, C/D box 116-2 0.00073148373 0.002087407571 -6.1674 0.0403 0.0418 0.0616 1.0906 0.1362 0.255726786 SNORD62A small nucleolar RNA, C/D box 62A 0.0022543551 0.005771553375 -6.1747 0.0234 1.6323 0.1370 0.0464 0.1897 0.1092100505753 KRTAP16-1 keratin associated protein 16-1 0.00083171154 0.002349935567 -6.1763 1.2286 1.6784 1.3075 0.6847 0.7474 0.82295332 PLCB4 phospholipase C, beta 4 0.00117893038 0.003227661954 -6.1786 0.1643 0.1938 0.2214 0.3806 0.0868 0.2578100124516 SNORD58C small nucleolar RNA, C/D box 58C 0.00067292406 0.00192994326 -6.1821 0.3073 2.1048 1.1782 0.3362 1.6004 0.61254332 MNDA myeloid cell nuclear differentiation antigen 0.00019281503 0.000622019099 -6.2006 0.1296 0.1533 0.4823 0.1229 0.1565 0.1513768097 HAR1B highly accelerated region 1B (non-protein coding) 0.00015255465 0.000502973392 -6.2008 2.0364 3.2850 1.4437 1.1897 2.1931 2.13795787 PTPRB protein tyrosine phosphatase, receptor type, B 0.0004167177 0.001252758457 -6.2311 0.1992 0.1133 0.3048 0.1112 0.1033 0.261626816 SNORD35A small nucleolar RNA, C/D box 35A 7.47582189E-05 0.000263957908 -6.2343 0.4382 0.5177 0.3446 0.2016 0.3685 0.2805339975 LOC339975 uncharacterized LOC339975 0.00056261868 0.001643249439 -6.2355 0.1229 0.3319 0.1904 0.4525 0.0606 0.695926772 SNORD4B small nucleolar RNA, C/D box 4B 0.00243240796 0.006186659002 -6.2373 0.2076 2.3197 1.0182 0.6137 1.1842 0.42858626 TP63 tumor protein p63 0.00016046736 0.000526496591 -6.2445 0.4182 0.1981 0.3085 0.4840 0.0872 0.20702206 MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.00012994624 0.000435649774 -6.2489 0.0806 0.0433 0.0567 0.3040 0.0326 0.1107

6563 SLC14A1 6.95001208E-07 3.75262449E-06 -6.2629 0.0855 0.0987 0.1801 0.1774 0.0225 0.149150632 CALY calcyon neuron-specific vesicular protein 7.79878927E-06 3.35608755E-05 -6.2702 1.6675 1.0985 1.2305 0.7068 0.4963 0.57381767 DNAH5 dynein, axonemal, heavy chain 6 0.00038344082 0.001162179071 -6.2750 0.0628 0.0334 0.1389 0.3438 0.0219 0.2581341056 LOC341056 SUMO1 activating enzyme subunit 1 pseudogene 0.00014452636 0.000479706753 -6.2750 0.0915 0.0164 0.1513 0.1301 0.0697 0.18554897 NRCAM neuronal cell adhesion molecule 3.90674221E-07 2.24336875E-06 -6.2783 0.3124 0.3578 0.4695 0.3056 0.2702 0.38743934 LCN2 lipocalin 2 0.00016295387 0.000533792225 -6.2970 0.0241 0.0658 0.1779 0.2346 0.0619 0.109654979 HRASLS2 HRAS-like suppressor 2 0.00064677078 0.001862536759 -6.3004 0.5297 0.2002 0.5772 0.4060 0.1169 0.2211132332 TMEM155 transmembrane protein 155 0.00073808013 0.002104588029 -6.3036 0.3287 0.2248 0.3641 0.3823 0.2149 0.406923242 COBL cordon-bleu WH2 repeat protein 0.00097845298 0.002725491827 -6.3129 0.1740 0.4489 0.2727 0.2553 0.2270 0.22112272 FHIT fragile histidine triad 4.25853395E-11 8.25153046E-10 -6.3227 2.4640 2.6340 2.4197 2.4215 2.3391 2.3237913 CD1E CD1e molecule 0.00018987928 0.000612981319 -6.3231 0.2416 0.1483 0.2089 0.4618 0.2330 0.2061100463486 MTRNR2L8 MT-RNR2-like 8 3.67486097E-10 5.02603608E-09 -6.3239 0.0338 0.0419 0.1730 0.0867 0.0329 0.1322723972 ANP32AP1 hepatopoietin PCn127 1.90618275E-06 9.36284172E-06 -6.3260 0.0609 0.1025 0.3652 0.2610 0.0332 0.2524100316904 SAP25 Sin3A-associated protein, 25kDa 7.472691E-10 9.13317792E-09 -6.3360 0.1061 0.1278 0.3104 0.0969 0.0679 0.1924167410 LIX1 Lix1 homolog (mouse) 0.00015278572 0.000503644356 -6.3420 0.1776 0.1362 0.3120 0.2466 0.0226 0.18259023 CH25H cholesterol 25-hydroxylase 0.00016917922 0.000552599684 -6.3541 2.9922 1.9440 2.1091 2.1810 1.3065 1.5755100820829 MYZAP myocardial zonula adherens protein 1.52112048E-05 6.143659E-05 -6.3584 0.2191 0.1755 0.2069 0.2881 0.2452 0.2825644246 KANSL1-AS1 KANSL1 antisense RNA 1 8.6264384E-10 1.03088478E-08 -6.3620 1.5907 1.8470 1.3304 1.5367 2.7180 1.5991100500805 MIR3607 microRNA 3607 0.00105732789 0.002921883731 -6.3638 0.8068 0.5743 0.3428 0.6554 0.4852 0.3211645142 PPIAL4D peptidylprolyl isomerase A (cyclophilin A)-like 4D 2.33859345E-05 9.07042656E-05 -6.3785 0.6404 0.6854 0.3993 1.0955 0.6465 0.3089692234 SNORD103A small nucleolar RNA, C/D box 103A 6.47585583E-06 2.83146298E-05 -6.3834 0.0836 0.1981 0.1458 0.2051 0.0447 0.20201397 CRIP2 cysteine-rich protein 2 1.16912548E-08 9.80820056E-08 -6.3842 0.7690 1.0312 0.7024 0.3515 1.0012 0.5412137735 ABRA actin-binding Rho activating protein 0.00053437427 0.001569032073 -6.3931 0.0914 0.1422 0.3545 0.1377 0.1047 0.1655284759 SIRPB2 signal-regulatory protein beta 2 0.00090340604 0.002536032455 -6.4104 0.4369 0.1590 0.3107 0.3145 0.0861 0.3565692110 SNORD70 small nucleolar RNA, C/D box 70 0.00017419145 0.000567045475 -6.4120 0.2908 0.9844 1.5724 0.6268 0.4439 0.7758100500850 MIR3682 microRNA 3682 0.00018662188 0.000603745556 -6.4276 0.0711 0.0296 0.0483 0.2860 0.0183 0.200951646 YPEL5 yippee-like 5 (Drosophila) 2.12742085E-12 7.77444677E-11 -6.4306 1.6005 2.9301 2.0565 1.6076 3.0183 2.4998727905 SPATA31A5 SPATA31 subfamily A, member 5 0.00080999987 0.0022933446 -6.4338 0.0414 0.0394 0.1541 0.5312 0.2280 0.22221379 CR1L complement component (3b/4b) receptor 1-like 2.43639868E-05 9.40982386E-05 -6.4354 0.8026 1.2540 0.6621 0.6488 1.0394 0.618579776 ZFHX4 zinc finger homeobox 4 0.00045554277 0.001355868639 -6.4402 0.6248 0.9653 0.7027 0.4273 0.6818 0.4426100131176 WDR86-AS1 WDR86 antisense RNA 1 2.19330742E-05 8.57059733E-05 -6.4417 0.9754 0.1102 0.7227 0.8561 0.0307 0.30507379 UPK2 uroplakin 2 1.20595956E-05 4.97972724E-05 -6.4510 0.2517 0.4062 0.4010 0.5309 0.1439 0.23238911 CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 2.13655093E-07 1.30959606E-06 -6.4548 0.2849 0.1548 0.4757 0.3657 0.1286 0.2618729786 GOLGA8CP golgin A8 family, member C, pseudogene 0.00021298471 0.000680954777 -6.4608 0.0353 0.0328 0.2297 0.3234 0.0301 0.2070100313824 MIR663B microRNA 663b 6.5198684E-05 0.000232723257 -6.4648 0.2656 0.0660 0.0519 0.9212 0.0811 0.535494163 SNORD38B small nucleolar RNA, C/D box 38B 7.12019911E-05 0.000252376873 -6.4688 0.0916 0.8507 1.0394 0.0782 0.2611 0.731524141 LAMP5 lysosomal-associated membrane protein family, member 5 0.00016180738 0.000530317274 -6.4773 0.1266 0.2725 0.1586 0.2948 0.1035 0.2162725 C4BPB complement component 4 binding protein, beta 3.18748932E-06 1.48597031E-05 -6.4838 1.4018 1.0042 1.3490 1.2970 0.4586 0.6390947 CD34 CD34 molecule 1.75773272E-07 1.09802708E-06 -6.5041 0.3837 0.8844 0.6735 0.4095 0.2926 0.4206

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

solute carrier family 14 (urea transporter), member 1 (Kidd blood group)

282997 PDCD4-AS1 hypothetical protein LOC282997 1.56141959E-10 2.40761677E-09 -6.5211 1.0584 1.0594 0.9291 0.7018 0.3125 0.548079633 FAT4 FAT atypical cadherin 4 0.00025266473 0.000798065692 -6.5369 0.5646 0.6772 0.3365 0.3483 0.6149 0.3248728622 SKP1P2 S-phase kinase-associated protein 1 pseudogene 2 7.05915342E-11 1.24894017E-09 -6.5407 0.0495 0.1121 0.2001 0.3596 0.0599 0.21014951 OCM2 oncomodulin 2 3.63009824E-06 1.67624855E-05 -6.5512 0.0108 0.0288 0.1081 0.1783 0.0170 0.2421642265 SPATA31A2 SPATA31 subfamily A, member 2 0.00039915723 0.00120651792 -6.5709 0.1212 0.0669 0.1061 0.5708 0.2411 0.30904256 MGP matrix Gla protein 0.00013005372 0.0004357861 -6.5750 0.8271 0.4334 0.3468 0.6390 0.2896 0.18781475 CSTA cystatin A (stefin A) 6.93722685E-06 3.01658755E-05 -6.5899 0.1507 0.2128 0.2487 0.0906 0.1408 0.2009693208 MIR623 microRNA 623 4.13889329E-05 0.000153461563 -6.5959 1.8509 1.4511 2.5451 1.2275 0.8629 1.220679937 CNTNAP3 contactin associated protein-like 3 0.00014653041 0.000485212709 -6.6141 0.6743 0.7341 1.1267 0.4999 0.2876 0.716622986 SORCS3 sortilin-related VPS10 domain containing receptor 3 2.13196725E-05 8.35412943E-05 -6.6183 0.1176 0.1675 0.4469 0.2776 0.4714 0.37638876 VNN1 vanin 1 2.44448849E-05 9.43907307E-05 -6.6404 0.1278 0.1261 0.2133 0.2098 0.0473 0.14437401 CLRN1 clarin 1 0.00056620515 0.001652931856 -6.6492 0.0728 0.1605 0.1171 0.2748 0.4779 0.1711645683 RPL13AP3 ribosomal protein L13a pseudogene 3 7.72275173E-10 9.40107392E-09 -6.6721 0.0640 0.1177 0.1296 0.2115 0.0506 0.202855350 VNN3 vanin 3 4.57638995E-05 0.000168147591 -6.6832 0.0610 0.1067 0.3590 0.4218 0.6041 0.4016115350 FCRL1 Fc receptor-like 1 1.22120538E-05 5.03471678E-05 -6.6836 0.1605 0.1600 0.1703 0.5090 0.1024 0.1912406896 MIR103A2 microRNA 103a-2 9.53071384E-05 0.000328824024 -6.6971 0.0384 0.2638 0.1357 0.5538 0.5166 0.0683121506 ERP27 endoplasmic reticulum protein 27 4.93041737E-13 2.65326755E-11 -6.7027 0.7668 0.4927 0.4625 0.9955 0.2143 0.3058400999 FLJ42351 uncharacterized LOC400999 2.84565141E-08 2.15660483E-07 -6.7099 0.8052 1.1978 0.9200 0.4992 0.7363 0.662653353 LRP1B low density lipoprotein receptor-related protein 1B 9.34310744E-05 0.000322838992 -6.7158 0.2715 0.7284 0.8033 0.5618 0.5387 0.6003342538 NACA2 nascent polypeptide-associated complex alpha subunit 2 1.60469664E-05 6.45268862E-05 -6.7239 0.0130 0.0347 0.2062 0.2640 0.0088 0.3280

3737 KCNA2 potassium voltage-gated channel, shaker-related subfamily, member 2 1.85625998E-06 9.13235926E-06 -6.7259 1.3328 2.5615 1.6266 0.9476 1.8623 0.8754285195 SLC9A9 solute carrier family 9 (sodium/hydrogen exchanger), member 9 3.19391714E-09 3.18903027E-08 -6.7288 2.5199 1.9761 1.4736 2.8159 1.0172 1.188326773 SNORD4A small nucleolar RNA, C/D box 4A 3.24480984E-05 0.000122397121 -6.7288 0.9693 3.9601 3.0623 0.3314 3.8170 1.7385

9037 SEMA5A 0.00056740014 0.001656155798 -6.7301 0.8901 4.8893 0.3804 2.5552 7.6299 0.195127306 HPGDS hematopoietic prostaglandin D synthase 0.00032963507 0.001015184909 -6.7443 0.4201 0.7084 0.5792 0.4661 0.1568 0.2472

728577 CNTNAP3B 0.00028995803 0.000903652244 -6.7568 0.1492 0.2509 0.3315 0.4915 0.1527 0.2013729233 PRR20B proline rich 20B 0.01476917883 0.030331846199 -6.7782 0.0283 0.0418 0.1656 0.2160 0.0372 0.2425728137 TSPY3 testis specific protein, Y-linked 3 0.0001718855 0.000559838113 -6.7949 0.0484 0.0727 0.2689 0.3208 0.3618 0.321053829 P2RY13 purinergic receptor P2Y, G-protein coupled, 13 7.0662114E-05 0.000250609112 -6.8020 0.5601 0.5425 0.5823 0.4370 0.2059 0.3325401260 LINC00951 long intergenic non-protein coding RNA 951 0.00054393769 0.001593271796 -6.8043 0.2993 0.4131 0.4641 0.2012 0.1156 0.3003693230 MIR645 microRNA 645 1.85737654E-05 7.36981197E-05 -6.8410 0.0564 0.0302 0.2617 0.0800 0.0211 0.0992654231 OCM oncomodulin 2.83043984E-07 1.6813328E-06 -6.8864 0.0734 0.0554 0.0896 0.1921 0.0029 0.0950100422875 MIR3192 microRNA 3192 0.00021992673 0.000701064411 -6.8870 0.2010 0.6608 0.2739 0.2304 0.8636 0.2957100500854 MIR3671 microRNA 3671 0.00017958215 0.000583067156 -6.8943 0.3483 0.4332 0.2862 0.4001 0.1284 0.1878219972 MPEG1 macrophage expressed gene 1 0.00040740317 0.00122920587 -6.9091 0.2008 0.2079 0.0952 0.3140 0.2340 0.155589795 NAV3 neuron navigator 3 0.00320227038 0.007908080061 -6.9282 0.0511 0.0219 0.0902 0.2242 0.0227 0.170894162 SNORD38A small nucleolar RNA, C/D box 38A 5.87199407E-05 0.000211373277 -6.9369 0.3321 0.3321 0.3321 0.3970 0.3970 0.397010178 TENM1 teneurin transmembrane protein 1 6.06392488E-10 7.66251973E-09 -6.9414 0.3402 0.0836 0.0926 0.2823 0.0466 0.082226799 SNORD50A small nucleolar RNA, C/D box 50A 1.15686703E-05 4.79000101E-05 -6.9504 2.9093 8.1149 1.2485 1.3470 7.2457 0.70646691 SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 5.67543459E-08 3.98698734E-07 -6.9539 1.4076 0.8805 0.9224 0.9925 0.8091 0.875926771 SNORD102 small nucleolar RNA, C/D box 102 1.80985478E-05 7.20158242E-05 -6.9793 1.4936 2.9778 0.5041 0.4010 2.2755 0.1908319101 KRT73 keratin 73 5.10858443E-09 4.79425037E-08 -6.9829 0.4209 0.6729 0.2867 0.4285 0.1564 0.2691911 CD1C CD1c molecule 0.00196062326 0.005090154612 -6.9880 0.1658 0.1924 0.4176 0.4148 0.0714 0.3121100500878 MIR3679 microRNA 3679 0.00015079767 0.000497629597 -7.0315 1.4919 1.9575 0.9506 1.1311 0.6044 0.4431100500815 MIR3687 microRNA 3687 6.24779329E-08 4.3592846E-07 -7.0424 0.0648 0.0582 0.1067 0.1458 0.0939 0.22599300 SNORD28 small nucleolar RNA, C/D box 28 3.03264606E-05 0.000115106998 -7.0786 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706036 RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00010384215 0.000355652053 -7.1047 0.4450 0.4325 0.4611 0.3704 0.2684 0.3699116159 CYYR1 cysteine/tyrosine-rich 1 0.00015999171 0.000525502172 -7.1097 0.6168 0.5872 0.2313 1.1392 0.9541 0.43723543 IGLL1 immunoglobulin lambda-like polypeptide 1 7.28283444E-06 3.1526167E-05 -7.1476 0.1179 0.0356 0.3976 0.1364 0.0912 0.2970724033 MIR663A microRNA 663a 1.51290515E-06 7.58195364E-06 -7.1524 0.4552 0.4065 0.4804 0.5642 0.1413 0.4939343068 PRAMEF5 PRAME family member 5 7.82394191E-05 0.000275557183 -7.1734 0.0398 0.1181 0.0878 0.2704 0.0342 0.24604018 LPA lipoprotein, Lp(a) 0.00013150394 0.000440000014 -7.1842 0.1480 0.0187 0.1043 0.2327 0.0106 0.1525100616406 MIR4521 microRNA 4521,microRNA 4521 2.00175111E-06 9.76577813E-06 -7.2000 6.3558 2.3605 3.1063 7.8961 1.7775 4.68453818 KLKB1 kallikrein B, plasma (Fletcher factor) 1 1.95212116E-05 7.70225824E-05 -7.2344 0.0532 0.0247 0.0748 0.2989 0.0291 0.1760641648 SNORD87 small nucleolar RNA, C/D box 87 9.45487426E-07 4.94587639E-06 -7.2729 1.0930 2.5816 1.2365 0.6591 2.0255 0.6761693153 MIR568 microRNA 568 7.78627118E-06 3.35148992E-05 -7.3489 0.2267 0.2708 1.1585 0.3206 0.1552 0.5281128346 C1orf162 chromosome 1 open reading frame 162 1.34602314E-09 1.51911888E-08 -7.3556 4.2492 1.3309 1.9774 4.6458 1.2499 1.58004069 LYZ lysozyme 5.03391076E-05 0.000183445587 -7.3662 0.2105 0.3264 0.1479 0.1731 0.3014 0.14473003 GZMK granzyme K (granzyme 3; tryptase II) 2.15166457E-07 1.31665154E-06 -7.3925 0.6595 0.7610 0.6863 0.6515 0.3218 0.2830

28 ABO 3.21736547E-08 2.39949803E-07 -7.4127 1.0625 1.8288 0.9048 0.9792 1.3781 0.923381030 ZBP1 Z-DNA binding protein 1 1.69202602E-07 1.06316023E-06 -7.4334 2.6745 2.6396 2.1195 1.8287 1.6703 1.1312619567 SNORD2 small nucleolar RNA, C/D box 2 1.57447928E-07 9.95118832E-07 -7.4336 1.8158 11.1264 4.4879 1.8591 31.5400 3.37001043 CD52 CD52 molecule 8.46337016E-13 3.81833826E-11 -7.4792 1.6657 0.6438 0.6392 0.4632 1.3154 0.53231831 TSC22D3 desmoplakin 2.02840897E-11 4.59269996E-10 -7.4878 2.1346 2.1532 2.1496 1.5438 2.1843 1.9405692088 SNORD50B small nucleolar RNA, C/D box 50B 2.22653123E-07 1.35610595E-06 -7.5165 0.3321 0.3321 0.3321 0.3970 0.3970 0.3970100132399 GAGE12D G antigen 12D 0.00040997962 0.001235551308 -7.5786 0.0465 0.0404 0.1177 0.2055 0.0504 0.221054504 CPVL carboxypeptidase, vitellogenic-like 6.42380961E-07 3.49332885E-06 -7.6919 0.6298 1.1605 0.7836 0.4519 0.6041 0.74531791 DNTT docking protein 1, 62kDa (downstream of tyrosine kinase 1) 1.10891031E-06 5.7204995E-06 -7.7332 0.6565 0.6658 0.6002 0.6479 0.4781 0.3372

407738 FAM19A1 5.40741656E-07 2.98773255E-06 -7.8195 0.3969 0.2237 0.2428 0.4549 0.1224 0.202527039 PKD2L2 polycystic kidney disease 2-like 2 4.82925668E-07 2.70178133E-06 -7.9286 1.8026 2.4934 2.1987 1.5960 2.3070 1.7157392490 FLJ44635 TPT1-like protein 3.92056931E-10 5.29674261E-09 -7.9990 0.9076 0.7438 0.7271 1.0739 0.3452 0.41672353 FOS FBJ murine osteosarcoma viral oncogene homolog 1.7343131E-12 6.58822638E-11 -8.0516 2.0539 4.2911 2.0806 1.9016 3.6378 1.93731378 CR1 complement component (3b/4b) receptor 1 (Knops blood group) 2.87525832E-07 1.70407785E-06 -8.0724 1.2326 1.3025 1.4467 0.9913 0.8318 0.943926769 SNORD81 small nucleolar RNA, C/D box 81 2.3514607E-14 3.06899214E-12 -8.1278 0.3321 0.3321 0.3321 0.3970 0.3970 0.397026805 SNORD45A small nucleolar RNA, C/D box 45A 3.44778527E-08 2.55466069E-07 -8.2630 2.2029 3.7395 2.2283 1.5758 7.0097 1.99643849 KRT2 keratin 2 2.18300329E-08 1.71265934E-07 -8.2998 0.1822 0.1511 0.2998 0.3342 0.0723 0.292726813 SNORD36C small nucleolar RNA, C/D box 36C 1.03168696E-10 1.70751669E-09 -8.3324 0.1863 1.8380 0.3684 0.1616 0.2285 0.201826815 SNORD36A small nucleolar RNA, C/D box 36A 5.11077168E-13 2.71465175E-11 -8.3394 0.3321 0.3321 0.3321 0.3970 0.3970 0.39706283 S100A12 S100 calcium binding protein A12 0.00041667273 0.001252758457 -8.3535 0.0648 0.1337 0.2106 0.2006 0.1406 0.251410462 CLEC10A C-type lectin domain family 10, member A 0.00163358825 0.004327185352 -8.3640 0.2227 0.2167 0.1350 0.1990 0.2498 0.14213957 LGALS2 lectin, galactoside-binding, soluble, 2 3.96596E-05 0.000147678869 -8.4142 0.6832 0.8823 0.4590 0.2957 0.1943 0.3079100130231 LINC00861 long intergenic non-protein coding RNA 861 2.8703797E-12 9.74862044E-11 -8.4318 4.0211 2.0010 2.2546 4.4668 1.0224 1.4291100462981 MTRNR2L2 MT-RNR2-like 2 2.19654641E-12 7.94758337E-11 -8.4647 0.0452 0.1122 0.3529 0.1163 0.0629 0.2810606500 SNORD68 small nucleolar RNA, C/D box 68 6.84464677E-13 3.29987825E-11 -8.6584 2.7925 1.9956 2.3947 0.7023 1.6624 1.87201990 CELA1 chymotrypsin-like elastase family, member 1 7.92702492E-07 4.22158553E-06 -8.6832 0.0496 0.0443 0.1270 0.2294 0.0221 0.1685

432369 ATP5EP2 4.53949679E-08 3.27719026E-07 -8.9321 0.0796 0.0768 0.1911 0.1735 0.0268 0.31982205 FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.94804033E-06 9.54022859E-06 -8.9477 0.0933 0.0612 0.0923 0.0630 0.1553 0.251584546 SNORD35B small nucleolar RNA, C/D box 35B 7.68200837E-11 1.3279627E-09 -9.1189 2.6393 4.9887 2.7418 1.9386 5.7843 1.4498100616387 MIR3064 microRNA 3064,microRNA 3064 3.4392133E-13 2.02062076E-11 -9.1804 0.1347 0.8239 0.5403 0.1320 0.7747 0.496864231 MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 4.15580207E-06 1.88939576E-05 -9.1879 0.1317 0.1549 0.2112 0.3745 0.2201 0.21572124 EVI2B ecotropic viral integration site 2B 2.43665658E-13 1.59579172E-11 -9.2525 4.3880 2.6878 0.9426 3.2951 1.4982 1.4812692227 SNORD104 small nucleolar RNA, C/D box 104 8.89081421E-12 2.35439068E-10 -9.2898 1.1009 2.5756 1.8039 0.8373 0.9007 0.7516100500819 MIR3609 microRNA 3609 2.56185938E-12 8.91624657E-11 -9.9615 0.3492 0.8121 0.4542 0.3244 0.3213 0.356310365 KLF2 Kruppel-like factor 2 9.75114681E-10 1.14360048E-08 -10.0509 0.9990 3.7536 1.9584 0.8276 2.2759 2.0017

83955 NACAP1 1.45850858E-11 3.52391731E-10 -10.0966 0.1831 0.0419 0.1803 0.2367 0.0387 0.1946440567 UQCRHL ubiquinol-cytochrome c reductase hinge protein-like 1.32520294E-16 1.3744062E-13 -11.5389 0.0398 0.0141 0.1859 0.2107 0.0511 0.1409100302285 MIR1244-1 microRNA 1244-1 7.14802783E-23 1.30608765E-18 -14.1334 0.3034 0.4480 0.2309 0.5414 0.5939 0.3242

sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

similar to Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3)

ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)

family with sequence similarity 19 (chemokine (C-C motif)-like), member A1

ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2

nascent-polypeptide-associated complex alpha polypeptide pseudogene 1