FINAL PROGRAM

CO U R S E D I R E C TO R SAntonio Colombo, MDEberhard Grube, MDMartin B. Leon, MDCarlo Di Mario, MDJeffrey W. Moses, MDGregg W. Stone, MDNicolas Van Mieghem, MD

JOINT INTERVENTIONAL MEETING IN PARTNERSHIP WITH

, Italy

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INTERVENTIONALCARDIOLOGYHD LIVE CASES

ADVANCEDAND BASIC WORKSHOPS

LEADERSHIP IN LIVE CASE DEMONSTRATION

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COURSE DIRECTORS

Antonio COLOMBO, MDEberhard GRUBE, MDMartin B. LEON, MDCarlo DI MARIO, MDJeffrey W. MOSES, MDGregg W. STONE, MDNicolas VAN MIEGHEM, MD

ASSOCIATE DIRECTORS

Alexandre C. ABIZAID, MDSeung JUNG PARK, MD Stephan WINDECKER, MD

PRESENTED BY

ST. RAFFAELE HOSPITAL Milan, Italy

COLUMBUS HOSPITAL HEART CENTER Milan, Italy

UNIVERSITY HOSPITAL BONN Bonn, Germany

THORAXCENTER ERASMUS UNIVERSITY MEDICAL CENTER Rotterdam, The Netherlands

LIVE SATELLITE TRANSMISSIONS

From Milan

From Bonn

From Rotterdam

Faculty Members

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ORGANIZING SECRETARIAT

Victory Project CongressiVia C. Poma, 220129 Milan • ItalyPhone +39 02 89 05 35 24Fax +39 02 20 13 95e-mail info@victoryproject.it

CONGRESS VENUE

Milan Marriott Hotel Via Washington, 6620146 Milan • ItalyPhone +39 02 48 521www.milanmarriotthotel.com

Program updated to February 15th 2018

Useful Addresses

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We are very pleased to welcome you in Milan on February 22 - 24, 2018!

The partnership with TCT/CRF is still an infusion of new energy to JIM to better deliver a fruitful educational experience to the attendee. JIM is “The Live Case Meeting” and it will keep this unique characteristic with an increase of time dedicated to live case discussion. Live demonstrations will include treatment of adult valvular heart  disease, structural heart disease. We will introduce new devices without loosing close contact to the daily practice of the busy Interventionist.

The meeting maintains its format with “State of the Art” lectures given by experts in the field. Lunch symposia fulfill this target.

Welcome !

This year we have again live transmission on Saturday morning (including Milan)  in order to maintain a well-balanced distribution of live cases throughout the entire meeting.

More emphasis and expansion are given to those sessions in which  attendees can present and discuss cases.

The Meeting will take place in Milan at Milan Marriott Hotel. It combines a comfortable accommodation solution with a large  and effi-cient Congress Centre.

Welcome in Milan!

Antonio Colombo, MD Eberhard Grube, MD

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Alexandre C. Abizaid, MDSao Paulo - Brazil

Eustachio Agricola, MDMilan - Italy

Yaron Almagor, MDJerusalem - Israel

Dominick J. Angiolillo, MDJacksonville, FL - USA

Marco Barbanti, MDCatania - Italy

Francesco Bedogni, MDMilan - Italy

Sergio Berti, MDMassa - Italy

Carlo Briguori, MDNaples - Italy

Todd Brinton, MDStanford, CA - USA

Maurice Buchbinder, MDLa Jolla, CA - USA

Lutz Buellesfeld, MDBonn – Germany

Francesco Burzotta, MDRome - Italy

Davide Capodanno, MDCatania - Italy

Mauro Carlino, MDMilan - Italy

Fausto Castriota, MDCotignola, RA - Italy

Alaide Chieffo, MDMilan - Italy

Bernardo Cortese, MDMilan - Italy

Invited Faculty

Alberto Cremonesi, MDCotignola, RA - Italy

Joseph DeGregorio, MDNew York, NY - USA

Joseph Dens, MDGenk - Belgium

Paolo Denti, MDMilan - Italy

Carlo Di Mario, MDFlorence - Italy

Giovanni Esposito, MDNaples - Italy

Franco Fabbiocchi, MDMilan - Italy

Ted Feldman, MDEvanston, IL - USA

Marco Ferlini, MDPavia - Italy

Sean Gallagher, MDCardiff - UK

Roberto Garbo, MDTurin - Italy

Gabriele Gasparini, MDRozzano, MI - Italy

Guido Gelpi, MDMilan - Italy

Francesco Giannini, MDMilan - Italy

Anand Gnanaraj, MDChennai - India

Rishi Gupta, MDFaridabad - India

Michael Haude, MDNeuss - Germany

Faculty Members

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Murugesh S. Hiremath, MDPune - India

Ajay Jain, MDLondon - UK

Paul Hsien-Li Kao, MDTaipei City - Taiwan

T.S. Kler, MDDehli - India

Herbert Kroon, MDRotterdam - The Netherlands

Karl Heinz Kuck, MDHamburg - Germany

Purshotam Lal, MDNoida, UP - India

Alessio La Manna, MDCatania - Italy

Azeem Latib, MDMilan - Italy

Michael Laule, MDBerlin - Germany

Martin B. Leon, MDNew York, NY – USA

Ugo Limbruno, MDGrosseto - Italy

Iqbal Malik, MDLondon - UK

Roxana Mehran, MDNew York, NY - USA

Oscar Mendiz, MDBuenos Aires - Argentina

Alberto Menozzi, MDParma - Italy

Jonathan Michel, MDMunich - Germany

Ghada Mikhail, MDLondon - UK

Jeffrey W. Moses, MDNew York, NY – USA

Issam Moussa, MDNew York, NY - USA

Giuseppe Musumeci, MDCuneo - Italy

Sunao Nakamura, MDTokyo – Japan

Georg Nickenig, MDBonn – Germany

Jacopo Andrea Oreglia, MDMilan – Italy

Jai-Wun Park, MDHamburg – Germany

Anna Sonia Petronio, MDPisa – Italy

Italo Porto, MDRome – Italy

Bernard Prendergast, MDLondon - UK

Patrizia Presbitero, MDTurin - Italy

S.K. Reddy, MDChandigah - India

Bernhard Reimers, MDRozzano, MI – Italy

Marco Roffi, MDGenève - Switzerland

Ariel Roguin, MDHaifa - Israel

Enrico Romagnoli, MDViterbo – Italy

Invited Faculty

Faculty Members

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Faculty Members

Invited Faculty

Roberta Rossini, MDCuneo - Italy

Gennaro Sardella, MDRome - Italy

Paul Christian Schulze, MDJena – Germany

Gioel Gabrio Secco, MDAlessandria – Italy

Paolo Sganzerla, MDTreviglio, BG – Italy

Horst Sievert, MDFrankfurt - Germany

Balbir Singh, MDGurgaon, Delhi - India

Mohamed Ahmed Sobhy, MDAlexandria - Egypt

Lars Sondergaard, MDCopenhagen - Denmark

Mark Spence, MDBelfast - UK

Goran Stankovic, MDBelgrade - Serbia

Giulio Stefanini, MDRozzano, MI - Italy

Gregg W. Stone, MDNew York, NY - USA

Corrado Tamburino, MDCatania - Italy

Giuseppe Tarantini, MDPadua - Italy

Luca Testa, MDMilan – Italy

Hendrik Treede, MDHalle, Saale - Germany

Nicolas Van Mieghem, MDRotterdam - The Netherlands

Ferdinando Varbella, MDOrbassano, TO - Italy

Francesco Versaci, MDRome - Italy

Marco Wainstein, MDPorto Alegre - Brazil

Ron Waksman, MDWashington, DC - USA

Yong-Jian Wu, MDBeijing - China

Alan Yeung, MDStanford, CA - Usa

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Faculty and OperatorsEberhard Grube, MD

Georg Nickenig, MDRobert Schueler, MDJan Malte Sinning, MDNikos Werner, MD

Faculty Members

University Hospital, Bonn

Cardiovascular Surgery DepartmentArmin Welz, MDFritz Mellert, MDWolfgang Schiller, MD

Anaesthesiology DepartmentAndreas Hoeft, MDStefan Weber, MD

Faculty and OperatorsAntonio Colombo, MD

Bruno Damascelli, MDLeo Finci, MDAzeem Latib, MDGloria Melzi, MD

Fellow and Research AssociatesOzan Mehemet Demir, MDDaisuke Hachinohe, MDSatoru Mitomo, MD

Columbus Hospital Center, Milan

Cardiology and Intensive Coronary Care SectionsRaffaella Alpago, MDGiancarlo Biagi, MDAlfredo Castelli, MDFederica Della Rocca, MD

Anaesthesiology DepartmentRomeo Arienta, MDStefano Fattore, MDAlberto Marazzi, MDStefano Tredici, MDPierluigi Villa, MD

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Faculty Members

Faculty and OperatorsAntonio Colombo, MDLorenzo Azzalini, MDMauro Carlino, MDAlfredo Castelli, MDAlaide Chieffo, MDFrancesco Giannini, MDAzeem Latib, MDMatteo Montorfano, MD

Fellows and Research AssociatesMarco Ancona, MDBarbara Bellini, MDOzan Demir, MDGianmarco Iannopollo, MDAntonio Mangieri, MDDamiano Regazzoli, MD

Cardiothoracic DepartmentOttavio Alfieri, MDSection Director Andrea Blasio, MDNicola Buzzati, MDMaria Chiara Calabrese, MDAlessandro Castiglioni, MDMicaela Cioni, MDMichele De Bonis, MDBenedetto Del Forno, MDPaolo Denti, MDDavid Ferrara, MDAndrea Giacomini, MDGiuseppe Iaci, MDGiovanni La Canna, MDElisabetta Lapenna, MDSimona Nascimbene, MDTeodora Nisi, MDPaola Redaelli, MDIside Stella Scarfò, MDCinzia Trumello, MDAlessandro Verzini, MD

Cardiology and Intensive Coronary Care SectionsAlberto Margonato, MDSection DirectorEustachio Agricola,MDCarlo Ballarotto, MDAlberto Cappelletti, MDAndrea Conversano, MDCosmo Godino, MDValeria Magni, MDMichele Oppizzi, MDStefano Stella, MD

San Raffaele Scientific Institute, Milan

Vascular Surgery SectionRoberto Chiesa, MD Section DirectorLuca Apruzzi, MDVincenzo Ardita, MDDomenico Astore, MDDomenico Baccellieri, MDLuca Bertoglio, MDMatteo Bossi, MDRenata Castellano, MDBarbara Catenaccio, MDGloria Esposito, MDAndrea luitz Kahlberg, MDDiletta Loschi, MDDaniele Mascia, MDGermano Melissano, MDEnrico Rinaldi, MDSara Spelta, MDYamume Tshomba, MD

Anaesthesiology and Cardiovascular Intensive Care SectionAlberto Zangrillo, MD Section DirectorElena Bignami, MDTiziana Bove, MDMariagrazia Calabrò, MDMartina Crivellari, MDFabrizio Monaco, MDAnnalisa Franco, MDChiara Gerli, MDFederico Pappalardo, MDMara Scandroglio, MD

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Società Italiana diCardiologia Interventistica

Patronages

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12.30 - 19.20 JIM - GISE FELLOWS COURSE ROOM MANZONI organized in partnership by JIM and GISE Coordinator: Francesco Giannini

12.30 - 13.00 Welcome light buffet lunch

13.00 - 14.00 Fundamentals of PCI Chairpersons: Francesco Giannini, Azeem Latib, Giuseppe Tarantini

13.00 Top lessons I got from cath lab activity and no study will ever show Antonio Colombo 13.20 Questions & Answers 13.30 The lessons I would have liked to get when I was a beginner Carlo Di Mario 13.50 Questions & Answers

14.00 - 14.45 PCI in complex anatomy Chairpersons: Carlo Di Mario, Nicolas Van Mieghem

14.00 Case I with interactive discussion Fausto Castriota 14.20 Case II with interactive discussion Marco Ferlini 14.40 Take home message Carlo Di Mario

14.45 - 15.30 Bifurcation lesions Chairpersons: Francesco Bedogni, Alaide Chieffo

14.45 Case I with interactive discussion Francesco Burzotta 15.05 Case II with interactive discussion Goran Stankovic 15.25 Take home message Alaide Chieffo

15.30 - 16.15 Primary PCI: when things are going badly! Chairpersons: Giuseppe Musumeci, Ron Waksman

15.30 Case I with interactive discussion Alberto Menozzi 15.50 Case II with interactive discussion Luca Testa 16.10 Take home message Giuseppe Musumeci

Wednesday, February 21st, 2018

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Wednesday, February 21st, 2018

16.15 - 17.20 CTO Chairpersons: Mauro Carlino, Sunao Nakamura

16.15 CTO Procedures: techniques and indications Alessio La Manna 16.35 Case I with interactive discussion Jacopo Andrea Oreglia 16.55 Case II with interactive discussion Roberto Garbo 17.15 Take home message Sunao Nakamura

17.20 - 17.35 Coffee break

17.35 - 17.55 Lecture How to handle difficult situations in cath lab Antonio Colombo

17.55 - 19.00 Getting out of troubles Chairpersons: Antonio Colombo, Giuseppe Tarantini

17.55 Case I with interactive discussion Gabriele Gasparini 18.15 Case II with interactive discussion Carlo Di Mario 18.35 Case III with interactive discussion Giovanni Esposito 18.55 Take home message Giuseppe Tarantini

19.00 - 19.20 Practical Session Tips and tricks on usage of Rotational Atherectomy Roberto Garbo

19.20 End of the Course

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MAIN HALL WASHINGTON

8.00 - 8.05 Welcome and Opening Address Antonio Colombo, Eberhard Grube Chairperson: Gregg W. Stone Co-chairperson: Nicolas Van Mieghem

8.05 - 9.45 LIVE CASES FROM BONN, GERMANY University Hospital Commentators: Marco Barbanti, Michael Haude, Karl Heinz Kuck, Oscar Mendiz, Ghada Mikhail Guest operators: Paul Hsien-Li Kao, Marco Wainstein On-line factoids relevant to the cases presented: Lorenzo Azzalini (Coordinator), Ozan Mehemet Demir, Damiano Regazzoli

9.45 - 10.00 Discussing the case

10.00 - 10.30 Coffee break 10.30 - 12.15 LIVE CASES FROM MILAN, ITALY St. Raffaele Hospital Commentators: Patrizia Presbitero, Gennaro Sardella, Horst Sievert, Mohamed Ahmed Sobhy, Goran Stankovic On-line factoids relevant to the cases presented: Lorenzo Azzalini (Coordinator), Ozan Mehemet Demir, Damiano Regazzoli

12.15 - 12.30 Discussing the case

12.45 - 14.15 Lunch Symposia

ROOM MANZONI DES 1

ROOM FOSCOLO TAVI 1

ROOM PORTA CTO

ROOM PARINI INTRACORONARY IMAGING

ROOM CLUB STRUCTURAL HEART 1

Thursday, February 22nd, 2018

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12.45 - 14.15 DES 1 ROOM MANZONI Chairpersons: Yaron Almagor, Carlo Briguori

12.45 Overview of new generation DES Gregg W. Stone 12.55 Up to 5 year clinical outcomes of Orsiro in complex lesions Ariel Roguin 13.05 COMBO+ EPC Capture DES: beyond proven concept to hard clinical evidence Roxana Mehran 13.15 A new generation abluminal coated Sirolimus Eluting Stent as a treatment option for diabetic patients Luca Testa 13.25 How to overachieve in a Left Main Bifurcation: imaging, stent and technique? Alessio La Manna 13.35 Cre8TM EVO: establishing a new DES benchmark for diabetic patients Gennaro Sardella 13.45 Questions & Answers

12.45 - 14.15 TAVI 1 ROOM FOSCOLO Chairpersons: Marco Barbanti, Karl Heinz Kuck

12.45 What’s new in TAVI 2018 Martin B. Leon 13.00 A tale of 2 valves. Acurate and Lotus: building a new chapter in TAVI Lars Sondergaard 13.15 What should be the standard for TAVI today and tomorrow? Jonathan Michel 13.30 TAVI in bicuspid aortic valve disease - Experiences from China Yong-Jian Wu 13.45 Evolut PRO latest innovation in TAVI. A workhorse device to treat all patients Anna Sonia Petronio 14.00 Questions & Answers

12.45 - 14.15 CTO ROOM PORTA Chairpersons: Roberto Garbo, Issam Moussa

12.45 What you need to know about new CTO wires Sunao Nakamura 13.00 Transferring CTO knowledge to daily practice Gabriele Gasparini 13.15 Revascularization strategies in CTO: a case-based discussion Joseph Dens 13.30 Complications during CTO procedures Jacopo Andrea Oreglia 13.45 A novel antegrade dissection/re-entry technique for CTO-PCI Mauro Carlino 14.00 Questions & Answers

LUNCH SYMPOSIA - Thursday

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LUNCH SYMPOSIA - Thursday

12.45 - 14.15 INTRACORONARY IMAGING ROOM PARINI Chairpersons: Carlo Di Mario, Ugo Limbruno

12.45 Calcific lesions: imaging for optimal lesion preparation Carlo Di Mario 13.00 The vulnerable patient. How to image, how to treat Ron Waksman 13.15 Stent optimization: how to use OCT and IVUS Enrico Romagnoli 13.30 Stent optimization: be careful with the edges Franco Fabbiocchi 13.45 Questions & Answers

12.45 - 14.15 STRUCTURAL HEART 1 ROOM CLUB Chairpersons: Lutz Buellesfeld, Bernard Prendergast

12.45 Is it time to expand LAA indication? Sergio Berti 12.55 Paravalvular leaks Horst Sievert 13.05 The ultraseal LAA experience Jai-Wun Park 13.15 PFO closure Iqbal Malik 13.25 Complex LAAC anatomies: a case-based discussion Mark Spence 13.35 Ready for prime time to combo Mitral & LAA? Giuseppe Tarantini 13.45 Questions & Answers

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Thursday, February 22nd, 2018

MAIN HALL WASHINGTON

Chairperson: Martin B. Leon Co-chairperson: Alexandre C. Abizaid

14.30 - 16.15 LIVE CASES FROM BONN, GERMANY University Hospital Commentators: Balbir Singh, Corrado Tamburino, Hendrik Treede, Ron Waksman, Alan Yeung Guest operators: Paul Hsien-Li Kao, Marco Wainstein On-line factoids relevant to the cases presented: Lorenzo Azzalini (Coordinator), Ozan Mehemet Demir, Damiano Regazzoli 16.15 - 16.30 Discussing the case

16.30 - 17.00 Coffee break 17.00 - 18.15 LIVE CASES FROM MILAN, ITALY St. Raffaele Hospital Commentators: Yaron Almagor, Carlo Briguori, Lutz Buellesfeld, Ted Feldman, Giuseppe Tarantini On-line factoids relevant to the cases presented: Lorenzo Azzalini (Coordinator), Ozan Mehemet Demir, Damiano Regazzoli

18.15 - 18.30 Discussing the case

18.45 - 20.15 Evening Symposium

ROOM MANZONI MANAGE A LARGE DISCREPANCY IN VESSEL DIAMETERS IN LEFT MAIN BIFURCATION LESIONS – IS A SELF APPOSING STENT THE ANSWER?

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EVENING SYMPOSIUM - Thursday

18.45 - 20.15 MANAGE A LARGE DISCREPANCY IN VESSEL DIAMETERS IN LEFT MAIN BIFURCATION LESIONS – IS A SELF APPOSING STENT THE ANSWER? ROOM MANZONI Chairpersons: Bernardo Cortese, Gennaro Sardella Discussants: Carlo Briguori, Gioel Gabrio Secco, Ferdinando Varbella

18.45 Introduction Gennaro Sardella 18.50 The current role of PCI for Left Main, the surgical perspective Guido Gelpi 19.00 Why use a self-apposing stent in Left Main PCI: anatomic and clinical considerations Bernardo Cortese 19.10 Discussion 19.15 Case 1: Case presentation Alessio La Manna Case discussion 19.30 Case 2: Case presentation Paolo Sganzerla Case discussion 19.45 Case 3: Case presentation Italo Porto Case discussion 20.00 Wrap-up Bernardo Cortese

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Friday, February 23rd, 2018

MAIN HALL WASHINGTON

Chairperson: Carlo Di Mario Co-chairperson: Roxana Mehran

8.00 - 9.45 LIVE CASES FROM BONN, GERMANY University Hospital Commentators Giuseppe Musumeci, Bernard Prendergast, Horst Sievert, Corrado Tamburino, Ron Waksman Guest operators: Paul Hsien-Li Kao, Marco Wainstein On-line factoids relevant to the cases presented: Francesco Giannini (Coordinator), Gianmarco Iannopollo, Antonio Mangieri 9.45 - 10.00 Discussing the case

10.00 - 10.30 Coffee break 10.30 - 12.15 LIVE CASES FROM MILAN, ITALY St. Raffaele Hospital Commentators: Michael Haude, Jeffrey W. Moses, S.K. Reddy, Gennaro Sardella, Francesco Versaci On-line factoids relevant to the cases presented: Francesco Giannini (Coordinator), Gianmarco Iannopollo, Antonio Mangieri

12.15 - 12.30 Discussing the case 12.30 - 12.35 Incathlab presentation Max Amor

12.45 - 14.15 Lunch Symposia

ROOM MANZONI DES 2 AND NEW BRS

ROOM FOSCOLO TAVI 2

ROOM PORTA STRUCTURAL HEART 2

ROOM CLUB INNOVATIVE TECHNOLOGIES

ROOM PARINI CLINICAL CROSSROADS ON OPTIMAL ANTITHROMBOTIC THERAPY IN PATIENTS TREATED WITH PCI

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12.45 - 14.15 DES 2 AND NEW BRS ROOM MANZONI Chairpersons: Bernhard Reimers, Alan Yeung

12.45 Delivering ultimate bifurcation treatment Goran Stankovic 12.55 The Synergy stent in high-risk patients: why design matters? Giulio Stefanini 13.05 Magmaris: the impact of scaffold design and materials on lowering scaffold thrombosis Michael Haude 13.15 Magic Touch: preliminary clinical evidence with a novel Sirolimus drug coated balloon Bernardo Cortese 13.25 Complexity made simple: Resolute Onyx the advanced workhorse Fausto Castriota 13.35 MVD in STEMI patients: safe solutions on challenging cases! Jacopo Andrea Oreglia 13.45 Questions & Answers

12.45 - 14.15 TAVI 2 ROOM FOSCOLO Chairpersons: Alberto Cremonesi, Corrado Tamburino

12.45 When is a patient not a good candidate for TAVI? Case example and general outline Marco Barbanti 13.00 Prime time for “Protected TAVI” Martin B. Leon 13.15 The EMBLOK embolic protection system early feasibility and safety study: preliminary results Azeem Latib 13.30 Next generation large bore closure device: • PerQseal Michael Laule • Manta Herbert Kroon 14.00 Questions & Answers

12.45 - 14.15 STRUCTURAL HEART 2 ROOM PORTA Chairpersons: Maurice Buchbinder, Horst Sievert

12.45 When to replace, when to repair Hendrik Treede 13.00 Transcatheter therapies for the forgotten valves Teld Feldman 13.15 Mitral valve replacement: ready for prime time! Bernard Prendergast 13.30 The role of ventricular unloading in heart recovery Paul Christian Schulze 13.45 Mitral valve repair. Transeptal complete ring delivery Azeem Latib 14.00 The first Core Valve case of the world Purshotam Lal 14.05 Questions & Answers

LUNCH SYMPOSIA - Friday

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LUNCH SYMPOSIA - Friday

12.45 - 14.15 INNOVATIVE TECHNOLOGIES ROOM CLUB Chairpersons: Davide Capodanno, Ron Waksman

12.45 PiCSO to reduce infarct size: update on clinical studies Ajay Jain 13.00 Left ventricular support during complex transradial PCI for complete revascularization Carlo Briguori 13.15 The evolution of Plaque Scoring: from lesion preparation to lesion treatment Sean Gallagher 13.30 DynamX: a novel metallic DES with adaptive remodeling Martin B. Leon 13.45 The role of Intravascular Lithotripsy for treatment of heavily calcified coronary lesions Todd J. Brinton 14.00 Questions & Answers

12.45 - 14.15 CLINICAL CROSSROADS ON OPTIMAL ANTITHROMBOTIC THERAPY IN PATIENTS TREATED WITH PCI ROOM PARINI Chairpersons: Giuseppe Musumeci, Gregg W. Stone

Intravenous antiplatelet therapy in high risk ACS 12.45 Clinical Case: High Risk ACS Giuseppe Tarantini 12.50 GPIIb/IIIa inhibitors are still the best option Alberto Menozzi 12.57 Cangrelor is ready for the prime time Dominick J. Angiolillo 13.04 Clinical case conclusion Giuseppe Tarantini 13.08 Discussion

Antithrobotic therapy in patients with non-valvular atrial fibrillation undergoing PCI 13.15 Clinical Case: PCI in AF patients Ferdinando Varbella 13.20 Short triple therapy and dedicated stents Ghada Mikhail 13.27 Dual therapy is the right choice Roxana Mehran 13.34 Clinical case conclusion Ferdinando Varbella 13.38 Discussion

Long-term antiplatelet therapy in high risk PCI patients 13.45 Clinical Case: Management of long-term DAPT Ugo Limbruno 13.50 Long term DAPT after ACS: balancing risks and benefits Marco Roffi 13.57 Perioperative management of patients with coronary stents undergoing requiring surgery: bridging therapy is an option Roberta Rossini 14.04 Clinical case conclusion Ugo Limbruno 14.08 Discussion

14.15 Closing remarks

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Friday, February 23rd, 2018

MAIN HALL WASHINGTON

Chairperson: Jeffrey W. Moses Co-chairperson: Maurice Buchbinder

14.30 - 15.45 LIVE CASES FROM BONN, GERMANY University Hospital Commentators: Alexandre C. Abizaid, Francesco Bedogni, Alberto Cremonesi, Ted Feldman, Alan Yeung Guest operators: Paul Hsien-Li Kao, Marco Wainstein On-line factoids relevant to the cases presented: Francesco Giannini (Coordinator), Gianmarco Iannopollo, Antonio Mangieri 15.45 - 16.00 Discussing the case

16.00 - 16.25 LIVE IN THE BOX. ACUTE NEURO INTERVENTION Bernhard Reimers Discussants: Patrizia Presbitero, Horst Sievert

16.25 - 17.00 Coffee break

17.00 - 18.00 LIVE CASES FROM ROTTERDAM, NL ThoraxCenter, Erasmus University Medical Center Commentators: Eustachio Agricola, Paolo Denti, Karl Heinz Kuck, Roxana Mehran, Hendrik Treede On-line factoids relevant to the cases presented: Francesco Giannini (Coordinator), Gianmarco Iannopollo, Antonio Mangieri

18.00 - 18.15 Discussing the case

18.30 - 20.00 Evening Symposia

ROOM MANZONI COMPLICATIONS IN INTERVENTIONAL CARDIOVASCULAR THERAPIES ROOM CLUB LEFT MAIN CONCLAVE

12.45 - 14.15 INNOVATIVE TECHNOLOGIES ROOM CLUB Chairpersons: Davide Capodanno, Ron Waksman

12.45 PiCSO to reduce infarct size: update on clinical studies Ajay Jain 13.00 Left ventricular support during complex transradial PCI for complete revascularization Carlo Briguori 13.15 The evolution of Plaque Scoring: from lesion preparation to lesion treatment Sean Gallagher 13.30 DynamX: a novel metallic DES with adaptive remodeling Martin B. Leon 13.45 The role of Intravascular Lithotripsy for treatment of heavily calcified coronary lesions Todd J. Brinton 14.00 Questions & Answers

12.45 - 14.15 CLINICAL CROSSROADS ON OPTIMAL ANTITHROMBOTIC THERAPY IN PATIENTS TREATED WITH PCI ROOM PARINI Chairpersons: Giuseppe Musumeci, Gregg W. Stone

Intravenous antiplatelet therapy in high risk ACS 12.45 Clinical Case: High Risk ACS Giuseppe Tarantini 12.50 GPIIb/IIIa inhibitors are still the best option Alberto Menozzi 12.57 Cangrelor is ready for the prime time Dominick J. Angiolillo 13.04 Clinical case conclusion Giuseppe Tarantini 13.08 Discussion

Antithrobotic therapy in patients with non-valvular atrial fibrillation undergoing PCI 13.15 Clinical Case: PCI in AF patients Ferdinando Varbella 13.20 Short triple therapy and dedicated stents Ghada Mikhail 13.27 Dual therapy is the right choice Roxana Mehran 13.34 Clinical case conclusion Ferdinando Varbella 13.38 Discussion

Long-term antiplatelet therapy in high risk PCI patients 13.45 Clinical Case: Management of long-term DAPT Ugo Limbruno 13.50 Long term DAPT after ACS: balancing risks and benefits Marco Roffi 13.57 Perioperative management of patients with coronary stents undergoing requiring surgery: bridging therapy is an option Roberta Rossini 14.04 Clinical case conclusion Ugo Limbruno 14.08 Discussion

14.15 Closing remarks

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EVENING SYMPOSIA - Friday

18.30 - 20.00 COMPLICATIONS IN INTERVENTIONAL CARDIOVASCULAR THERAPIES ROOM MANZONI Why did it happen, how did you manage it,  how will you prevent it in the future with the support of Complex Interventional Cardiovascular Therapy Chairpersons: Issam Moussa, Joseph DeGregorio

Coronary interventions complications 18.30 Case 1: Case presentation Joseph DeGregorio Case discussion 18.45 Case 2: Case presentation Goran Stankovic Case discussion

Structural heart disease interventions complications 19.00 Case 1: Case presentation Bernhard Reimers Case discussion 19.15 Case 2: Case presentation Carlo Briguori Case discussion

Vascular interventions complications 19.30 Case 1: Case presentation Bernhard Reimers Case discussion 19.45 Case 2: Case presentation Issam Moussa Case discussion

18.30 - 20.00 LEFT MAIN CONCLAVE ROOM CLUB Chairperson: Antonio Colombo Panel: Martin B. Leon, Jeffrey W. Moses, Gregg W. Stone

18.30 Learn from the experts. Left main bifurcation: where are we today? Guidelines, decision making and strategies Alaide Chieffo 18.42 Managing an acute occluded LM Balbir Singh 18.52 Rotablation in left main bifurcation Purshotam Lal 19.02 LM stenting: be prepared for the worst T.S. Kler 19.12 Distal LM with bifurcation Rishi Gupta 19.22 Distal LM with trifurcation S.K. Reddy 19.32 Impact of imaging in LM PCI Anand Gnanaraj 19.42 Optimizing LM bifurcation lesion Murugesh S. Hiremath 19.52 Wrap-up Antonio Colombo

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MAIN HALL WASHINGTON

Chairpersons of the day: Eberhard Grube, Martin B. Leon

8.30 - 9.30 LIVE CASES FROM MILAN, ITALY Columbus Hospital Commentators: Anand Gnanaraj, Ghada Mikhail, Issam Moussa, Mohamed Ahmed Sobhy, Ferdinando Varbella Guest operator: Sunao Nakamura On-line factoids relevant to the cases presented: Lorenzo Azzalini (Coordinator), Marco Ancona, Barbara Bellini

9.30 - 10.15 Selected LIVE IN THE BOX from SOUTH AMERICA Presenters: Alexandre C. Abizaid, Oscar Mendiz Discussants: Antonio Colombo, Eberhard Grube, Nicolas Van Mieghem

10.15 - 11.30 CASES PRESENTATION Ioannis Iakovou Athens - Greece Herbert Kroon Rotterdam - The Netherlands Carlo Briguori, Annamaria D’Achille Naples - Italy Eugene Wu Hong Kong Giuseppe Venuti Catania - Italy Shinji Imura Shizuoka - Japan Athanasios Kolyviras Athens - Greece Tiziana Attisano Salerno - Italy Murugesh S. Hiremath Pune - India

11.30 - 12.15 Selected LIVE IN THE BOX from EUROPE Presenters: Georg Nickenig, Azeem Latib Discussants: Antonio Colombo, Eberhard Grube, Nicolas Van Mieghem

12.15 Closing remarks and JIM 2019 announcement

Saturday, February 24th, 2018

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JIM 2018 Scientific Committee have selected the following posters:

P1. Association study of +808 T/G variant in ERRFI1 gene with Coronary In-Stent Restenosis in patients undergoing percutaneous coronary intervention (PCI) Seyed Kianoosh Hosseini, Samaneh Enayati, Abbas Mohagheghi, Mahsa M. Amoli

P2. Two generations of Bioresorbable Vascular Scaffold in comparison: clinical, angiographic and computed tomography follow-up Giampiero Vizzari, Antonio Trivisonno, Giuseppe Biondi Zoccai, Giuseppe Andò, Laura Gatto, Francesco Prati, Francesco Romeo, Francesco Versaci 

P3. Valve-In-(BENTALL’S)valve transcatheter aortic valve implantation(TAVI): protect the coronary ostiums and see the femoral access Gurbhej Singh, Giovanni Sorropago, Gioacchino Valenti, Andrea Demarchi, Jessica Rossi, Antonio Sorropago, Filippo Scalise

P5. 7.4 cm Iliac Aneurysm: PCI to High Risk Patient Ngoc Nguyen, Rameez Sayyed

P6. A rare culmination of a not so rare cardiac intervention- hemolysis post mitral valve repair Ashik Sasidharan

P7. Is it really cholesterol paradox? The level of low density lipoprotein cholesterol was lower in post-myocardial infarction patients with cardiac death. One year follow-up analysis of korean acute myocardial infarction registry - National Institute of Health (KAMIR-NIH) Jei-Keon Chae, Ja-yeon Lee, Sang-Rok Lee and KAMIR-NIH investigators

Selected Posters

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Selected Posters

P8. Percutaneous revascularisation strategy for ST-Elevation myocardial infarction with multi-vessel disease: findings from a South-East Asian Registry Hee Hwa Ho, Kwok Kong Loh, Timothy James Watson, Fahim Haider Jafary, Paul Jau Lueng Ong

P9. FFR and iFR role in therapeutic management and medium term prognosis in single and multi-vessel coronaropathy: a single center experience M. Ruozzi, M. Greco, S. Arrotti, F. Sgura, D. Monopoli, G.Boriani

P10. Left ventricle unloading during high-risk percutaneous coronary intervention with pulsatile left ventricular mechanical support Bastos MB, Daemen J, Schreuder J, Van Mieghem NM

P11. Immediate clinical impact of cerebral embolic protection with TAVI Kroon HG, Van Gils L, El Faquir N, Rahhab Z, Daemen J, De Jaegere P, Van Mieghem NM

Poster Set up and RemovalSet up on Thursday, February 22nd from 10.45 to 12.30Removal on Saturday, February 24th by 14.00

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General Information

Organizing Secretariat

Victory Project Congressi Via C. Poma, 2 - 20129 Milan - Italy Phone: +39 02 89 05 35 24 Fax: +39 02 20 13 95 e-mail: info@victoryproject.it

Secretariat on Site

Secretariat and Registration Desk at Congress Venue will be on duty from February 21 through 24.

Opening hours February 21 12.00 am - 7.30 pmFebruary 22 7.00 am - 8.00 pmFebruary 23 7.30 am - 8.00 pm February 24 8.00 am - 1.00 pm

Coffee and refreshment

Coffee and refreshment will be organized in the Exhibition area.

Lunch Buffet for Exhibitors

Buffet lunch will be served in Restaurant La Brasserie subject to presentation of the daily ticket.

Symposia for Physicians, Industry Professionals, Fellows and Nurses Symposia will be organized in Room Manzoni, Room Foscolo, Room Porta, Room Parini and Room Club. Participation is subject to presentation of the daily ticket (food and beverages included),to be picked up at the Secretariat Desk.

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Language

English is the official language of the Congress.No simultaneous translation is available.

Computer Center

A Computer Center will be available in the Congress Area. To allow a smooth running of sessions, Speakers are requested to contact this center and hand in their presentation at least one hour before the beginning of their session or the previous afternoon for the morning sessions.

Poster

Selected posters will be displayed in the Congress Area throughout the meeting.

General Information

TV direction and coordination by:Mr. Sandro AlliCoordination of technical equipment by: Mr. Paolo Torreggiani - LVS Solution Website by: Extra.it TecnomovieEDP Management by: JOY Solutions Expert

In compliance with EBAC/EACCME guidelines, all speakers/chairpersons participating in this program have disclosed or indicated potential conflicts of interest which might cause a bias in the presentations. The Organizing Committee/Course Director is responsible for ensuring that all potential conflicts of interest relevant to the Programme are declared to the audience prior to the CME activities.

Certificate of attendance

A certificate of attendance will be given to all registered participants upon presentation of their badge at the Secretariat Desk on Saturday, February 24, 2018.

EBAC CME Accreditation

The Joint Interventional Meeting JIM 2018 is accredited by the European Board for Accreditation in Cardiology (EBAC) for 15 hours of external CME credits.

Each participant should claim only those hours of credit that have actually been spent in the educational activity. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS).

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Registration fees

Physicians 1.000,00 ESpecial fare for GISE Member 700,00 EFellows, nurses, technicians 320,00 EIndustry Professionals (not having a stand) 1.000,00 EExhibitors (having a stand) 465,00 EFellow Course (on Wednesday 21) included (prices are in Euro and include VAT)

IMPORTANTA fixed price of € 150,00 will be charged for:• replacement of lost badge• name change of a registered participant

No show at the congress will be charged the full fee.

Full registration fee for Physicians, Industry Professionals, Fellows, Nurses and Technicians includes:• Admission to all Scientific Sessions • Coffee and refreshment• Entrance to the Exhibition • Congress kit• All Symposia (lunch included) Registration fee for Exhibitors includes: • Entrance to the Exhibition • Entrance to the Main Hall for Live Case sessions• Coffee and refreshment • Buffet lunch in “La Brasserie” • Congress kit • Lunch Symposia: only if sponsor of the Symposium

Only registered participants are allowed to attend scientific sessions.

Participants are requested to wear their badge for all the Congress events.

Registration

www.fondevidence.orgwww.fondevidence.orgFondazione Evidence per Attività e Ricerche Cardiovascolari - Onlus

Sede Legale: Via Donizetti, 30 - 20122 Milano - ItalyPh. +39 335 67 51 553 Y mail: fondevidence@gmail.com

Y coordinates and develops cardiovascular researchYcontributes to the formation of professional figures in this fieldYpromotes meetings, seminars and conferences in accordance with the aims of the foundation

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HOTEL

Milan Marriott Hotel IIII Congress venue Via Washington, 66 - 20146 Milano

Hotel Cristoforo Colombo IIII Corso Buenos Aires, 3 - 20124 Milano

Hotel Capitol Milano IIII Via Domenico Cimarosa, 6 - 20144 Milano

Hotel Wagner IIII Via Michelangelo Buonarroti, 13 - 20149 Milano

Hotel Map

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Milan Marriott Hotel Via Washington, 66 20146 Milan - Italy Phone +39 02 48 521

By PlaneFrom the airports of Milan Malpensa and Milan Linate you can take a shuttle bus to the central station.Or by taxi, estimated fare:- from Malpensa: € 90 (one way)- From Linate: € 35 (one way)

By TrainThe Milan Central Station is about 8 km away from the hotel.

By Car From the Freeway East (Tangenziale Est) exit Via Certosa and follow signs to Fiera Milano City. Once in Piazza Giulio Cesare, turn right to Piazza Piemonte.From there, take Via Washington, where the hotel is located.

By UndergroundThe nearest underground station is Wagner (red line), at about 1 km from the hotel.

By BusBus line 61

ParkingA private parking is available. Fee: € 2,10/hour, € 15/day

How to get to Milan Marriott Hotel

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Congress Center

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COFFEE BREAK

Milan Marriott Hotel, MilanFebruary 22 -24, 2018

EXPO AREA 1

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Exhibitors

COMPANY STANDABBOTT stand 7BIOSENSORS INTERNATIONAL stand 17BOSTON SCIENTIFIC stand 10BRACCO IMAGING ITALIA stand 12CARDIO ALEX 2018 stand ACARDIOVASCULAR NEWS stand DCHIESI FARMACEUTICI stand 14CORDIS - CARDINAL HEALTH stand 1CRF - Cardiovascular Research Foundation stand IEDIZIONI MINERVA MEDICA stand NENDOTECH stand 11ERCULES COMUNICAZIONI stand FEUKON - SMT stand 18EUROIMAGE RESEARCH stand EFONDAZIONE EVIDENCE stand MGEM stand 4GISE - Società italiana di Cardiologia Interventistica stand LINCATHLAB - GUERBET stand 9INNOVA HTS stand 8KARDIA stand 2-3 MEDTRONIC stand 6MVSIC 2018 stand COCCLUTECH ITALIA stand 13ORBUSNEICH stand 5PHILIPS stand 16TERUMO stand 19-20VIVASURE MEDICAL stand 15WISEPRESS MEDICAL BOOKSHOP stand H

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Acknowledgements

Thanks to:

ABBOTT

ABIOMED EUROPE

ALVIMEDICA

BIOSENSORS INTERNATIONAL

BIOTRONIK

BOSTON SCIENTIFIC

BRACCO IMAGING ITALIA

CHIESI FARMACEUTICI

CICT - Complex Interventional Cardiovascular Therapy

CONCEPT MEDICAL

CORDIS - CARDINAL HEALTH

CORREVIO ITALIA

EDWARDS LIFESCIENCES

ELIXIR MEDICAL CORPORATION

ENDOTECH

ENVISION SCIENTIFIC

ESSENTIAL MEDICAL

EUKON-SMT

FONDAZIONE EVIDENCE

GEM

GUERBET

INNOVA HTS

INNOVATIVE CARDIOVASCULARSOLUTIONS

INTRAMEDICALS

KARDIA

MEDINOL

MEDTRONIC

MILLIPEDE

MIRACOR MEDICAL SYSTEMS

OCCLUTECH ITALIA

ORBUSNEICH

PHILIPS

SHOCKWAVE MEDICAL

STENTYS

TERUMO

VENUS MEDTECH

VIVASURE MEDICAL

WISEPRESS MEDICAL BOOKSHOP

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Major Sponsors

The Directors of the Course particularly wish to thank for their support in the organization of JIM 2018:

They also express their gratitude to:

O R G A N I Z I N G S E C R E TA R I ATVictory Project Congressi

Via C. Poma, 2 - 20129 Milan - ItalyPhone +39 02 89 05 35 24

Fax +39 02 20 13 95E-mail info@victoryproject.it

CO N G R E S S V E N U EMilan Marriott HotelVia Washington, 66 20146 Milan - Italy

F U R T H E R I N F O R M AT I O Nwww.jim-vascular.com

JOINT INTERVENTIONAL MEETING

WE LOOK FORWARD TO WELCOMING

ALL OUR FRIENDS AT

JIM 201914 -16 FEBRUARY

IN MILAN!