Extract Tribulus Summary · Traditionally tribulus fruit has been used in the folk medicine of...
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Herbal Extract Company of Australia The See full monograph for referencing, available at: www.herbalextracts.com.au Version: aug16/01 Tribulus Traditional and empirical use The Latin name tribulus originally meant a thorny plant or thistle. Traditionally tribulus fruit has been used in the folk medicine of India, China, Bulgaria and South Africa for a variety of reproductive conditions such as infertility and sexual impotence, as well as for muscle strength, oedemas, abdominal distention, cardiovascular diseases and general health. There is no well-documented information on the traditional use of tribulus leaf. Constituents The steroidal saponins are considered to be the factor responsible for the biological activity of products derived from tribulus. The steroidal saponin component of tribulus includes constituents such as protodioscin, diosgenin, tribulosin, yamogenin, epismilagenin, tigogenin, neotigogenin, gitogenin and neogitogenin, terrestrinins A (1) and B (2). New saponins continue to be isolated from tribulus fruit however their significance has not yet been determined. Beta- sitosterol, vitamin C, potassium and calcium have been isolated from the fruit. The alkaloids harmane and norharmane have been identified and are believed to contribute to causing the staggers in stock that graze on it. Actions Diuretic, demulcent, aphrodisiac, tonic. Indications • Urinary disorders: cystitis, kidney stones, oedema • Reproductive conditions: infertility, sexual impotence, decreased libido • Coronary heart disease • Muscle strength • Gout • Cough Toxicity Toxicity levels in humans are not known but tribulus is known to cause hepatogenous (liver) photosensitisation in sheep and goats, characterised by hepatic damage and non-pigmented skin predisposed to sunburn. Use in pregnancy Not recommended during pregnancy or lactation due to lack of sufficient data. Contraindications and cautions Tribulus appears to be generally safe. One case of pneumothorax (collapsed lung) upon digestion of the fruit has been reported. Drug interactions Controlled studies are not available and currently no interactions are known. Administration and dosage Liquid extract 1:1 60% alcohol : 10 to 20mL weekly (Tribulus terrestris) Clinical Summary
Transcript of Extract Tribulus Summary · Traditionally tribulus fruit has been used in the folk medicine of...
Herbal ExtractCompany of Australia
TheSee full monograph for referencing, available at:www.herbalextracts.com.auVersion: aug16/01
TribulusTraditional and empirical useThe Latin name tribulus originally meant a thorny plant or thistle. Traditionally tribulus fruit has been used in the folk medicine of India, China, Bulgaria and South Africa for a variety of reproductive conditions such as infertility and sexual impotence, as well as for muscle strength, oedemas, abdominal distention, cardiovascular diseases and general health. There is no well-documented information on the traditional use of tribulus leaf.
ConstituentsThe steroidal saponins are considered to be the factor responsible for the biological activity of products derived from tribulus. The steroidal saponin component of tribulus includes constituents such as protodioscin, diosgenin, tribulosin, yamogenin, epismilagenin, tigogenin, neotigogenin, gitogenin and neogitogenin, terrestrinins A (1) and B (2). New saponins continue to be isolated from tribulus fruit however their signifi cance has not yet been determined. Beta-sitosterol, vitamin C, potassium and calcium have been isolated from the fruit. The alkaloids harmane and norharmane have been identifi ed and are believed to contribute to causing the staggers in stock that graze on it.
ActionsDiuretic, demulcent, aphrodisiac, tonic.
Indications• Urinary disorders: cystitis, kidney stones, oedema• Reproductive conditions: infertility, sexual impotence, decreased libido• Coronary heart disease• Muscle strength• Gout• Cough
ToxicityToxicity levels in humans are not known but tribulus is known to cause hepatogenous (liver) photosensitisation in sheep and goats, characterised by hepatic damage and non-pigmented skin predisposed to sunburn.
Use in pregnancyNot recommended during pregnancy or lactation due to lack of suffi cient data.
Contraindications and cautionsTribulus appears to be generally safe. One case of pneumothorax (collapsed lung) upon digestion of the fruit has been reported.
Drug interactionsControlled studies are not available and currently no interactions are known.
Administration and dosageLiquid extract 1:1 60% alcohol : 10 to 20mL weekly
(Tribulus terrestris)
Clinical Summary
