Excimer Laser Complications and Their Management

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    Dr. Rupal Shah

    New Vision Laser Centers

    Vadodara-Mumbai-Amdavad

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    Excimer LaserComplications and

    their Management

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    Complications

    Complications common to LASIK and PRK

    Complications of PRK

    Complications of LASIK

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    Overcorrection

    Must be distinguished from slow healing

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    Overcorrection

    Must be distinguished from slow healing

    Characterized by high hyperopic overshoot

    in the first week

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    Overcorrection

    Must be distinguished from slow healing

    Characterized by high hyperopic overshoot

    in the first week

    After PRK, hyperopic PRK after 6-8

    months works well

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    Overcorrection

    Must be distinguished from slow healing

    Characterized by high hyperopic overshoot in the

    first week After PRK, hyperopic PRK after 6-8 months

    works well

    After LASIK, holmium laser LTK may be a betteroption than hyperopic PRK

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    UnderCorrection

    Usually due to problems of laser calibration

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    UnderCorrection

    Usually due to problems of laser calibration

    Should be distinguished from regression

    after the treatment

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    UnderCorrection

    Usually due to problems of laser calibration

    Should be distinguished from regression after the

    treatment After PRK, retreatment after 3-4 months works

    well, after tapering steroids quickly

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    UnderCorrection

    Usually due to problems of laser calibration

    Should be distinguished from regression after the

    treatment After PRK, retreatment after 3-4 months works

    well, after tapering steroids quickly

    After LASIK, lift the flap and retreat in the firstmonth itself

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    Decentration

    Not a very big problem in LASIK

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    Decentration

    Not a very big problem in LASIK

    Usually not a big problem in PRK-USE

    LARGE ZONES

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    Decentration

    Not a very big problem in LASIK

    Usually not a big problem in PRK-USE

    LARGE ZONES

    In hyperopic treatments, centration is very

    critical -USE LARGE ZONES

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    Decentration

    Not a very big problem in LASIK

    Usually not a big problem in PRK-USE LARGE

    ZONES In hyperopic treatments, centration is very critical

    -USE LARGE ZONES

    Myopic decentrations can be tackled by enlarging

    the zone while using masking fluids

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    Complications of PRK

    Epithelium Related

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    Complications of PRK

    Epithelium Related

    Steroid Related

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    Complications of PRK

    Epithelium Related

    Steroid Related

    Wound Healing Related

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    Epithelium Related-Filamentary

    Keratitis Especially common when patient has a

    cold or during summer

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    Epithelium Related-Filamentary

    Keratitis Especially common when patient has a cold

    or during summer

    Results in Foreign body sensation

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    Epithelium Related-Filamentary

    Keratitis Especially common when patient has a cold

    or during summer

    Results in Foreign body sensation

    Can be resolved by simple patching.

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    Epithelium Related-Filamentary

    Keratitis Especially common when patient has a cold

    or during summer

    Results in Foreign body sensation

    Can be resolved by simple patching.

    If the patient is very uncomfortable,

    filaments can be picked off with a fine

    forceps on the slit lamp

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    Epithelium Related-Heaping in

    the centre Occurs in hyperopic treatments-no laser

    energy in the centre

    Looks like a central island on topography

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    Epithelium Related-Heaping in

    the centre Occurs in hyperopic treatments-no laser

    energy in the centre

    Looks like a central island on topography

    Reduced BCVA

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    Epithelium Related-Heaping in

    the centre Occurs in hyperopic treatments-no laser

    energy in the centre

    Looks like a central island on topography

    Reduced BCVA

    Can be managed by polishing the cornea

    after epithelial scraping

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    Epithelium Related-Slow Growth

    The defect created does not heal

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    Epithelium Related-Slow Growth

    The defect created does not heal

    Can result due to systemic problems, the

    use of extra thick Bandage Contact Lenses,or due to injury

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    Epithelium Related-Slow Growth

    The defect created does not heal

    Can result due to systemic problems, the

    use of extra thick Bandage Contact Lenses,or due to injury

    Can be managed like a recurrent corneal

    erosion

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    Epithelium Related-Sterile

    Infiltrates Usually because of use of NSAIDS for pain

    relief during the healing phase

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    Epithelium Related-Sterile

    Infiltrates Usually because of use of NSAIDS for pain

    relief during the healing phase

    Give NSAIDS only under steroid cover

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    Steroid Related-IOP Rise

    Temporary increase of IOP even on FML

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    Steroid Related-IOP Rise

    Temporary increase of IOP even on FML

    Leads to loss of BCVA, and myopic shift

    due to corneal oedema

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    Steroid Related-IOP Rise

    Temporary increase of IOP even on FML

    Leads to loss of BCVA, and myopic shift

    due to corneal oedema

    Relief by Betablockers

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    Steroid Related-IOP Rise

    Temporary increase of IOP even on FML

    Leads to loss of BCVA, and myopic shift

    due to corneal oedema

    Relief by Betablockers

    Occassional recourse to Diamox

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    Steroid Related-Cataract

    Happens especially if the individual must

    take recourse to systemic steroids

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    Steroid Related-Cataract

    Happens especially if the individual must

    take recourse to systemic steroids

    Avoid all patients with even slight lenticularchanges pre-op

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    Steroid Related-Cataract

    Happens especially if the individual must

    take recourse to systemic steroids

    Avoid all patients with even slight lenticularchanges pre-op

    Must warn Asthamatics about possibility of

    cataract

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    Wound Healing-Slow Healing

    Must be distinguished from over correction

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    Wound Healing-Slow Healing

    Must be distinguished from over correction

    Patient treated for myopia stays hyperopic

    for very long

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    Wound Healing-Slow Healing

    Must be distinguished from over correction

    Patient treated for myopia stays hyperopic

    for very long

    Thinner Epithelium in the center of the

    cornea

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    Wound Healing-Slow Healing

    Must be distinguished from over correction

    Patient treated for myopia stays hyperopic

    for very long

    Thinner Epithelium in the center of the

    cornea

    Taper Steroids quickly

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    Wound Healing-Slow Healing

    Must be distinguished from over correction

    Patient treated for myopia stays hyperopic for very

    long Thinner Epithelium in the center of the cornea

    Taper Steroids quickly

    Use a Bandage Contact Lens to stimulateepithelial healing

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    Wound Healing-Haze and

    Regression Peaks at 2 months in moderate myopia, and

    even at 8 months in extreme myopia

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    Wound Healing-Haze and

    Regression Peaks at 2 months in moderate myopia, and

    even at 8 months in extreme myopia

    Usually the haze is not visually significant,and this haze is not accompanied by

    regression

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    Wound Healing-Haze and

    Regression Peaks at 2 months in moderate myopia, and

    even at 8 months in extreme myopia

    Usually the haze is not visually significant,and this haze is not accompanied by

    regression

    Visually significant Haze is alwaysaccompanied by regression

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    Haze and Regression-

    Predisposing Factors Depth of the Ablation

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    Haze and Regression-

    Predisposing Factors Depth of the Ablation

    Shape of the Ablation pattern

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    Haze and Regression-

    Predisposing Factors Depth of the Ablation

    Shape of the Ablation pattern

    UV Light Exposure

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    Haze and Regression-

    Predisposing Factors Depth of the Ablation

    Shape of the Ablation pattern

    UV Light Exposure

    Fate of the fellow eye

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    Haze and Regression-

    Predisposing Factors Depth of the Ablation

    Shape of the Ablation pattern

    UV Light Exposure

    Fate of the fellow eye

    Hormonal changes-Pregnancy,HRT,Oral

    Contraceptives

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    Haze and Regression-

    Predisposing Factors Depth of the Ablation

    Shape of the Ablation pattern

    UV Light Exposure Fate of the fellow eye

    Hormonal changes-Pregnancy,HRT,Oral

    Contraceptives

    Previous Corneal Surgery-LASIK or RK

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    Haze and Regression-

    Management Give a Short burst of potent topical steroid

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    Haze and Regression-

    Management Give a Short burst of potent topical steroid

    Epithelial scraping and polishing of the

    haze-PROCEED WITH EXTREMECAUTION AND AFTER WAITING FOR

    1 YEAR FOLLOWING TREATMENT

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    Haze and Regression-

    Management Give a Short burst of potent topical steroid

    Epithelial scraping and polishing of the haze-

    PROCEED WITH EXTREME CAUTION ANDAFTER WAITING FOR 1 YEAR FOLLOWING

    TREATMENT

    Wait, Wait, Wait.., and the haze (but not the

    regression) goes away

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    COMPLICATIONS OF LASIK

    Intraoperative

    Immediately Post Operative

    Long Term

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    Intraoperative-Inadequate Flap

    Keratome movement is interrupted during

    the pass

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    Intraoperative-Inadequate Flap

    Keratome movement is interrupted during

    the pass

    Also happens in high and Low-K eyeswithout apparent reason

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    Intraoperative-Inadequate Flap

    Keratome movement is interrupted during

    the pass

    Also happens in high and Low-K eyes If Hinge is 2 mm beyond pupil center,

    reduce optical zone and proceed

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    Intraoperative-Inadequate Flap

    Keratome movement is interrupted during

    the pass

    Also happens in high and Low-K eyes If Hinge is 2 mm beyond pupil center,

    reduce optical zone and proceed

    Else, wait for 3-4 months, and repeatkeratome cut with greater depth

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    Intraoperative-Free Cap

    Can occur because of suction loss during

    the keratome pass

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    Intraoperative-Free Cap

    Can occur because of suction loss during

    the keratome pass

    Can also occur if hinge is too small andbreaks

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    Intraoperative-Free Cap

    Can occur because of suction loss during

    the keratome pass

    Can also occur if hinge is too small andbreaks

    Cap sticks back without sutures

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    Intraoperative-Free Cap

    Can occur because of suction loss during

    the keratome pass

    Can also occur if hinge is too small andbreaks

    Cap sticks back without sutures

    PARARADIAL AND RADIAL MARKSVERY IMPORTANT

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    Thin Flap

    Occurs because suction is not adequate

    If thinner than 70-80 microns, abandon

    procedure, repeat at a later date

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    Thin Flap

    Occurs because suction is not adequate

    If thinner than 70-80 microns, abandon

    procedure, repeat at a later date Else, if attempted correction is not high,

    convert to PRK, by cutting off the hinge

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    Epithelial Abrasion

    Occurs because of mishandling of flap, or

    due to the microkeratome itself

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    Epithelial Abrasion

    Occurs because of mishandling of flap, or

    due to the microkeratome itself

    Place a BCL to allow abrasion to heal

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    Epithelial Abrasion

    Occurs because of mishandling of flap, or

    due to the microkeratome itself

    Place a BCL to allow abrasion to heal Put patient on a higher steroid regimen

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    Post Op.-Displaced Flap

    Always see on Day 1

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    Post Op.-Displaced Flap

    Always see on Day 1

    Lift Flap, Clean interface, replace Flap

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    Post Op.-Displaced Flap

    Always see on Day 1

    Lift Flap, Clean interface, replace Flap

    Place a Bandage Contact Lens and a drop ofviscoelastic on top of the lens

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    Flap Oedema

    Can happen as a result of excessive

    washing, or because of a toxic chemical

    reaction

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    Flap Oedema

    Can happen as a result of excessive

    washing, or because of a toxic chemical

    reaction Resolves on waiting

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    Flap Oedema

    Can happen as a result of excessive

    washing, or because of a toxic chemical

    reaction Resolves on waiting

    Hypertonic Saline may be tried

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    Acute Inflammatory Reaction

    Can happen because of toxic chemical

    reaction

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    Acute Inflammatory Reaction

    Can happen because of toxic chemical

    reaction

    Must try a short dose of a potent topicalsteriod

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    Long Term-Haze

    Happens Very Rarely

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    Long Term-Haze

    Happens Very Rarely

    Occurs with thin flaps and or epithelial

    abrasion

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    Long Term-Haze

    Happens Very Rarely

    Occurs with thin flaps and or epithelial

    abrasion Treat as in PRK

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    THANK YOU