Evidence-Based Personalized Health & Nutrition

Biomarker I/O Pitch Deck

A Demand For Personalization

i. Demand for personalized nutrition is on the rise with an estimated CAGR of 6.5% and total value of $93 Billion in 2015expected to reach $127 Billion in 2020

ii. Existing methods for e-commerce supplement companies to personalize their offerings for customers are limited, unscientific or expensive

iii. With 46% of Americans now considered active digital health adopters, we are presented with an opportunity to offer an automated & data-driven solution for supplement companies to personalize their sales

2

In 2014 while working in the supplement industry, our team was met with a growing customer demand that was difficult to meet

Source: ”50 things we now know about digital health consumers | Rock Health ...."Source: "Dietary Supplements in an Age of Personalized Nutrition; How the ...." 4 Feb. 2016

Biomarker I/O Pitch Deck

A Team Tailored For Personalized Nutrition

3

Expertise In Nutraceutical Manufacturing, Healthcare Diagnostics & Constructing Cloud-based EHR Solutions

Partners & Investors

Garrett T. RuhlandCEO & FOUNDER

Dr. Nicholas LaucisCLINICAL RESEARCHER

James FallonSOFTWARE ENGINEER

Dr. Jim FallonMEDICAL ADVISOR

Joe MarchicaEXECUTIVE ADVISOR

Full-Time Thought-Leader Former Startup Founder Prior Exit or M&A

Dr. Molly MaloofMEDICAL ADVISOR

Dr. Adam RizviMEDICAL ADVISOR

Owais AhmadTECHNICAL ADVISOR

Pramod DabirTECHNICAL ADVISOR

Albert ChowEXECUTIVE ADVISOR

Scott KraftMARKETING & STRATEGY ADVISOR

Kostja MirkovicSALES & OPERATIONS

Part-Time

Biomarker I/O Pitch Deck 4

A turn-key personalized nutrition platform for online supplement companies

Meeting the Demand with Biomarker I/O

An evidence-based health & nutrition platform built for supplement companies

looking to give their customers a personalized shopping experience using

digital health

Biomarker I/O Pitch Deck 5

71% of AmericansTake supplements each year

$368 per CustomerU.S. Median Annual Spend on Supplements per Buyer

96% Confidence RatingU.S. Supplement Buyer Confidence In Safety, Quality & Efficacy of the Supplements They Buy

Source: "Online Vitamin & Supplement Sales Market Research | IBISWorld." Source: " ...." 22 Jun. 2016 Source: "New companies are competing to make the vitamin space…”- Digiday." 18 Apr. 2017Source: "Online Vitamin & Supplement Sales Market Research | IBISWorld." http://www.ibisworld.com/industry/online-vitamin-supplement-sales.html.

The Majority of Americans…

Who Buys Supplements?

Biomarker I/O Pitch Deck

A Highly Competitive Supplement Landscape

6

E-Commerce is the fastest growing sales channel in the U.S. Supplement Industry

Source: "Online Vitamin & Supplement Sales Market Research | IBISWorld." Source: " ...." 22 Jun. 2016 Source: "New companies are competing to make the vitamin space…”- Digiday." 18 Apr. 2017Source: "Online Vitamin & Supplement Sales Market Research | IBISWorld." http://www.ibisworld.com/industry/online-vitamin-supplement-sales.html.

$133 Billion $41.4 BillionGlobal Supplement Market US Supplement Market

$7 Billion 12% GrowthUS E-Commerce Sales US E-Commerce Sales

17%

17%

19%

20%

21%

22%

23%

28%

30%

42%

Joint Health

Digestive/Gastrointestinal Health

Skin, Hair & Nails

Healthy Aging

Heart Health

Bone Health

Immune Health

To Fill in Nutrient Gaps in My Diet

Energy

Overall Health/Wellness Benefits

Top Reasons For Supplement Use Among Supplement Users, 2016 N=1430

Biomarker I/O Pitch Deck

The Right Timing for Personalized Nutrition

7

Digital Health Adoption has sparked a convergence of data & nutrition

Source: "The 2016 HealthMine Digital Health Report." http://www.healthmine.com/sites/default/files/HealthMine Digital Health Tools Report May 2016.pdf

165,000 Health AppsDowloaded 1.7 billion times

46% Active Adopters3+ Digital Health tools

59% Use Apps DailyActive Digital Health Adopters

Personalized/Subscription Supplements

Lab Tests + Su

pp

lemen

ts/Foo

d

Supplement Information W

earables + Su

pp

lemen

ts

$15.5M – Series A

$15M

$2.82M $32M – Campbell’s

$52.6M – 3 Rounds

$6.6M

Biomarker I/O Pitch Deck

Supplement Industry Analysis

8

3 Factors Exist to Drive Success in the Industry – Biomarker I/O Automates Them

Source: "Online Vitamin & Supplement Sales Market Research | IBISWorld." http://www.ibisworld.com/industry/online-vitamin-supplement-sales.html.

Technical Knowledge After-Sales Service Control of Stock

Definition 1. Engagement1. How well a company knows their product.

1. Retention1. How you keep your customer coming back to buy your

product

1. Product Control 1. Control of supply chain, ingredients, raw material etc.

Current Solutions

1. Product Claims1. Clinical studies, Third-party/peer-reviewed journals,

Testimonials/endorsements2. Order Personalization

1. Online Quizzes, Dietitians, Lab/genetic services

1. Promotions/Discounts2. E-books/educational content3. Email marketing

1. Outsource vs. Purchase2. Warehouse, shipping, raw material, formulation & manufacturing

facilities

Risks

1. Product Claims Risk1. Costly, Time-Consuming & Risk Claims Violation

2. Order Personalization1. Unscientific, low ROI, not automated or scalable

1. Promotions/Discounts1. Lower Margin

2. E-Books/Educations Content1. Time consuming, costly & early copied by competitors

3. Email Marketing

1. High churn, little innovation

Notable Examples

1. Elysium 1. (Clinical Study $17M Funding)

2. truBrain 1. (Controlled Study)

3. Prevagen 1. (Aggressive Claims)

1. Weil’s Vitamins 2. Bulletproof Coffee3. Nootrobox

1. Amazon 1. 10% Market Share

2. Swanson3. bodybuilding.com

With Biomarker I/O

Automated Product Reports ✓ Use demographic health insights to differentiate product via published

Biomarker reports

Personalized Orders✓ Users can create custom regimens, A/B test different SKUs and order

through the platform

Biometric Driven Marketing✓ Drive campaigns for product promotions towards customers that have

responded best to similar products

Targeted Engagement✓ Engage in notifications, targeted content and group studies based on user

health data

Ingredient Forecasting✓ Use customer health insights to forecast critical ingredients driving product

efficacy✓ Remove low margin, low efficacy ingredients✓ Create new SKU’s based on existing customer data

Biomarker I/O Pitch Deck 9

Using Digital Phenotypes to Drive Personalization

Evidence-Based Nutrition

1000+

Parameters

Standardize

Data

Digital Phenotype (Baseline)

Use

r H

ealt

h

Heart Rate Calories

Sleep Mood

Digital Phenotype (Product A)

Use

r H

ealt

h

Digital Phenotype (Product B)

Use

r H

ealt

h

Activity Trackers

Nutrition Apps

Glucometers

Heart Rate Monitors

Gym Equipment

Blood Pressure Monitors

Sleep Trackers

Pulse Oximeters

400+ Integrations

Scales

Rx Compliance Apps

Spirometers

Thermometers

EMR’s

Labs

Microbiome

Custom Integrations

Biomarker I/O Pitch Deck 10

Customize Your Biomarker I/O Account For Your Business Needs

A Suite of Features to Increase User Engagement & Retention

1-Click Digital Health ConnectorConnect any cloud based application, device or database in seconds

Daily Journal Create custom journals with targeted push notifications to capture user behavior

Customized RegimensGive users the power to create personalized regimens with your product line.

Intake FormPersonalized intake forms designed to capture user preferences, goals and medical history.

Personalized StudiesIncrease customer engagement through evidence-based at home studies with your products.

E-Commerce MarketplaceConnect your Shopify or Amazon Store or sell directly through the Biomarker I/O platform

Custom KnowledgebaseConnect third party or custom databases containing dietary, medical and product information

Biomarker I/O Pitch Deck

• Contract Type

✓ 12-Month SaaS Agreement

✓ Avg. Setup fee ~ $7.3K

• Recurring Fees

✓ $2 / user / month

✓ $125 / admin / month

• Adoption Strategy

✓ Category Creation

✓ New clients acquired via word-of-mouth, pilots & partnerships

• Target Client

✓ Online e-commerce supplement companies with need for personalization

✓ Emphasis on sports nutrition, subscription e-commerce & cognitive health

11Source: "Online Vitamin & Supplement Sales Market Research | IBISWorld." http://www.ibisworld.com/industry/online-vitamin-supplement-sales.html. Source: Nutrition Business Journal, 2016

TAM$133B

SAM$41.4

SOM$7B 1,945 170M $368

# of Companies # of US Buyers Median Spend

Global Supplement Market US Supplement Market US Online Supplement Market US Online Supplement Companies

US Supplement Buyers US Supplement Buyer Annual Spend

Market

3 Live 9 Pipeline 1 Pilot 27,000 250Clients Supplement Companies Enterprise End-Users Admin Users

Beta Testing with Biomarker I/O (NDA)

Currently customizing Top 3 Global Supplement Manufacturer

Q4 Projected End-Users Q4 Projected Admin-Users

Customers

$101K $80K $6K 90% 45 daysInitial Sales ACV CAC Margin To Close New Client

Beta & Pilot Setup Fee’s Estimated annual contract value Estimated Customer Acquisition Cost

Software Margin Avg. Days to Close Client

Sales

Early Traction & SalesBusiness Model, Current Sales & Growth Strategy

Biomarker I/O Pitch Deck

Capital & Milestones

12

We’re raising a $1.5M seed

Capital $275k ($4.5M cap) Angel Round — Closed $1.5 million ($7M cap) Seed — Open

Focus Product/Market Fit: product refinement, lead gen Growth: build sales team, product refinement

Primary Objective (complete)✓ 403 digital health API’s✓ Surveyed over 1,500 supplement consumers✓ 6 Clients✓ $60k sales

Unplanned Progress (Complete)✓ 1 Enterprise Pilot✓ Reduced procurement timeline from 3-4

months to 4-5 weeks

Past Angel Round (closed) Present – 18 months

Objectives (Sales)➡ > 500K connected users➡ 50 Clients ➡ 4 hires

Objectives (Product)➡ HIPAA compliance across all tiers ➡ Predictive Product Matching➡ Release iOS/Android ➡ Release EMR/EHR 1-click integration tool➡ 6 hires

Biomarker I/O Pitch Deck 13

Biomarker I/O is an evidence-based health & nutrition platform built for supplement companies looking to give their customers a personalized shopping experience using digital health

Take Away

Customers Investors Pilot Partners HiresE-Commerce Supplement

Subscription Focus$1.5M Seed

Angels, Strategic, Early VCEnterpriseStrategic

Data ScientistB2B SaaS Salesman

Asks

Demand

✓ Supplement buyers demand personalized nutrition

Problem

✓ E-Commerce supplement companies have few ways to meet the demand

Trigger

✓ Digital Health adoption offers a way to non-invasively personalize supplement sales

Solution

✓ A turnkey Digital Health Platform for supplement companies to meet the demand

Contact: Garrett Ruhland, CEO

Email: garrett@biomarker.io

Phone: 714.345.8126

Office: 180 Sansome St. San Francisco CA, 94104

Website: www.biomarker.io

Beta: www.app.biomarker.io

Angellist: https://angel.co/biomarker

Contact Information