European Workshop on Quantitative Imaging for Molecular Radiotherapy: Metrology for Clinical Practice The workshop

The European Workshop on Quantitative Imaging for molecular radiotherapy will be held on 05-06 April 2017 at BEV in Vienna. The workshop will focus on calibration and validation of quantitative imaging for dosimetry in molecular radiotherapy as well as providing an introduction and overview of the EMPIR MRTDosimetry project devoted to providing state of the art dosimetry and protocols for clinical practice.

Emphasis is given to presentation and discussion of methods currently implemented at different centres and establishing an effective forum for discussion. The aim of the workshop is to agree on standard calibration methods that can be developed by the MRTDosimetry project as the basis of an international dosimetry protocol. It is important that the experience of the MRT community is represented as widely as possible.

Attending the workshop is free, but please register by email until 31 March 2017 to hannah.wiedner@bev.gv.at to help us plan. Please also let us know if you want to attend dinner on the evening of 5 April.

For more information about the project and workshop programme, please visit http://mrtdosimetry-empir.eu/.

Venue

5 – 6 April 2017

Bundesamt für Eich- und Vermessungswesen Schiffamtsgasse 1-3 1020 Wien Austria

Meeting room, 8th floor Phone: +43 1 21110 www.bev.gv.at

Program

Wednesday, 05 April

10:30 Welcome and opening of the workshop 20:00

10:40 Franz Josef Maringer, Bundesamt für Eich- und Vermessungswesen International metrology infrastructure and research

10:50 Vere Smyth and Andrew Robinson, National Physical Laboratory The MRTDosimetry project In

trod

uctio

n

11:10 James Scuffham, Royal Surrey County Hospital

Calibration of a QI system at Royal Surrey County Hospital - practicalities from a hospital physicist perspective

Dinner at „Griechenbeisl" Griechengasse 9/Fleischmarkt 11,

1010 Wien

Tel.: +43 1 5331977, office@griechenbeisl.at

Din

ner

11:30 Maria Kotzasarlidou, "Theagenio" Hospital of Thessaloniki Department's methods for 223Ra and 131I dosimetry

11:50 Katarina Sjörgreen Gleisner, Lunds Universitet Our clinical procedure for 177Lu dosimetry

12:10 Maria Kotzasarlidou, "Theagenio" Hospital of Thessaloniki Establishment of patient specific dosimetry in clinical routine

12:30 Thiago Lima, Kantonsspital Aarau Overview of the Swiss Nuclear Medicine Dosimetry Method

12:50 Stephan Witoszynskyj, Allgemeines Krankenhaus Wien Stumbling towards (accurate) quantitative imaging

13:10

Discussion on clinical practice and future developments A

: clin

ical

pra

ctic

e in

mol

ecul

ar ra

diot

hera

py

13:40

Lunch/coffee break

14:40 Keynote Brian Hutton, University College London Dealing with partial volume and motion effects in SPECT quantification

15:20 Keynote Eric Frey, Johns Hopkins How to achieve QI measurements of activity in arbitrary volumes in patients within an acceptable level of uncertainty

16:00 Gwennaëlle Marin, Université Libre de Bruxelles

Towards a quality assurance for dosimetry in fractionated MRT 16:20

Coffee break 16:40 Nick Bates, Royal Surrey County Hospital

On the dependence of gamma camera image uniformity on count-rate for 131I

17:00 Johan Gustafson, Lunds Universitet Segmentation of kidneys and tumors from 3D SPECT images

17:20 Wencke Lehnert, ABX-CRO Quantitative Imaging and Dosimetry in Clinical Trials from a CRO Perspective

17:40 Elisa Grassi, Arcispedale Santa Maria Nuova Azienda Ospedaliera Preliminary results of therapy response and toxicity analysis in a clinical PRRT trial

18:00

Discussion on QI methods and needs

B: m

etho

ds fo

r qua

ntita

tive

imag

ing

18:30 End of day 1

Thursday, 06 April

09:00

Keynote Irène Buvat, Service Hospitalier Frédéric Joliot Issues in quantitative imaging

09:40 Hugo Levillain, Université Libre de Bruxelles Quality assurance of activity administration in Selective Internal Radiation Therapy (SIRT)

10:00 Lidia Strigari, Istituti Fisioterapici Ospitalieri Image quantification and dosimetry at the National Cancer Institute Regina Elena, Rome

10:20 Johannes Tran-Gia, Universitätsklinikum Würzburg 3D Printing for the Calibration of SPECT/CT Systems

10:40 Domenico Finocchiaro, Arcispedale Santa Maria Nuova Azienda Ospedaliera A recovery coefficient method for partial volume correction of spect images in PRRT

11:00 Michael Lassmann, Universitätsklinikum Würzburg Accurate Dose Mapping after Endoradiotherapy with 177Lu-DOTATATE/-TOC by One-Single Measurement after 96 h

11:20 Coffee break

11:50 Domenico Finocchiaro, Arcispedale Santa Maria Nuova Azienda Ospedaliera Validation of a voxel-dosimetry and radiobiology tool for patient specific peptide receptor radionuclide therapy

12:10 Francesca Botta, Istituto Europeo di Oncologia Pre-treatment dosimetry with patient relative calibration for 90Y-microspheres radioembolization: the impact of 99mTcMAA-SPECT corrections

12:30 Discussion on methods on dose modelling quality assurance,

calibration and validation

13:00

Lunch/coffee break

14:00 Jonathan Gear, Institute of Cancer Research SPECT based Organ and Lesion Dosimetry for 90Y/111In PRRT

14:30 Carlo Chiesa, Istituto Nazionale Tumori Methodology and results of planar calibration with 131I and 177Lu in INT (Milan)

14:50 Michael Ljungberg, Lunds Universitet Problems associated with acquisiton, calibration and quantification

15:10 Kristof Baete, Universitaire ziekenhuizen Leuven Traceable Quantification for 68Ga based PET/CT

15:30 Gian Luca Poli, IAEA IAEA activities in the field of dosimetry for Radiopharmaceutical Therapy

15:50

Discussion and conclusions: future developments, needs, harmonisation of protocols and procedures and clinical implementation

C: d

osim

etry

, cal

ibat

ion

and

valid

atio

n

16:40 End of workshop

Invited speakers

Brian Hutton, University College London, UK Eric Frey, Johns Hopkins, USA Irène Buvat, CEA Service Hospitalier Frédéric Joliot, FR Carlo Chiesa, Istituto Nazionale Tumori, IT Gian Luca Poli, IAEA, UN Lidia Strigari, Istituti Fisioterapici Ospitalieri, IT Jonathan Gear, Institute of Cancer Research, UK James Scuffham, Royal Surrey County Hospital, UK

Public transport

To get to BEV, take U4 or U2 to Schottenring and take the exit “Herminengasse”. In case you take U4, in station Schottenring follow the signs to U2 first and take exit “Herminengasse”. After a short walk you will reach BEV.

Single trip tickets are € 2.20. There are several short-term tickets available (24 hour, 48 hour, 72 hour, 1 week, 8 days, etc). Check out www.wienerlinien.at for more information. The tickets are valid in Kernzone 100, which means you can take every train, tram, bus and underground within the bounds of Vienna. If you go outside Vienna, e.g. to the airport, you have to validate another € 2.20 ticket.

Public transport route planner

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If you arrive by plane…

The Vienna International Airport (VIE) in Schwechat is about 20 km south-east of Vienna. Transportation available at the airport:

• Train S7 to Landstraße/Wien Mitte, change to line U4 in direction Heiligenstadt and go to station “Schottenring”

• Bus Service Vienna Airport Lines (Travel time approx. 35 minutes) VIA to Wien Schwedenplatz (nearest BEV) VIA to UNO-City VIA to Wien Südtiroler Platz VIA to Wien Südbahnhof VIA to Wien Westbahnhof

• City Airport Train (CAT) • A Taxi stand is right in front of the Arrival Hall (approx. 40 €, approx. 30 min travel time) • Carsharing (approx. 30 - 40 min travel time, depending on the time of day)

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If you arrive by train…

If you arrive by train at Wien Hauptbahnhof you can take the subway U1 in direction Leopoldau to Karlsplatz and change to line U4 in direction Heiligenstadt. Go to station “Schottenring”. Hotels

Here are some hotel suggestions in the city centre that are very conveniently located for visiting BEV. Still, Vienna has a lot of hotels and booking.com should give you an overview if you want to book something else. For visiting BEV, direct access to subway lines U2 and U4 is useful.

Hotel de France, Schottenring 3, 01. Innere Stadt, 1010 Wien, 14 min on foot

Hotel Mercure Wien City, Hollandstraße 3, 02. Leopoldstadt, 1020 Wien, 6 min on foot

Meininger Hotel Downtown Sissi, Schiffamtsgasse 15, 02. Leopoldstadt, 1020 Wien, 3 min on foot

Meininger Hotel Downtown Franz, Rembrandtstraße 21, 02. Leopoldstadt, 1020 Wien, 6 min on foot

Tourist Information

Tourist-Info Vienna Albertinaplatz/Maysedergasse 1010 Vienna Daily from 9.00 am - 7.00 pm

Vienna Hotels & Info phone: +43-1-24 555 | fax: +43-1-24 555-666 Monday - Saturday, 9.00 am - 7.00 pm mail: info@vienna.info

Tourist Info Vienna Airport in the arrival hall Daily from 7.00 am - 10.00 pm

Tourist Info Vienna Main Station (Hauptbahnhof) Hauptbahnhof, ÖBB InfoPoint Daily from 9.00 am - 5.00 pm

Dinner

The dinner will be take place on 05 April at Restaurant „Griechenbeisl". We will meet there around 20:00.

Griechenbeisl, Griechengasse 9/Fleischmarkt 11, 1010 Wien. Tel.: +43 1 5331977, office@griechenbeisl.at.

Contact

Please don’t hesitate to contact me if you need any further information! I wish you a safe journey!

Email: hannah.wiedner@bev.gv.at Phone: +43 1 21110 6375 Mobile: +43 650 55 44 747

Email: franz-josef.maringer@bev.gv.at Phone: +43 1 21110 6372 Mobile: +43 676 8210 6372

Subway system of Vienna

BEV