Esophageal CA

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    ESOPHAGEAL CANCER

    Esophageal cancer is a cancerous(malignant) tumor of the esophagus, the

    muscular tube that moves food from the

    mouth to the stomach.

    Esophageal cancer can be of two cell type:

    adenocarcinoma and squamous cell

    carcinoma.

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    PATHOPHYSIOLOGYRisk factor:

    Chronic ingestion of hot liquids or food , GERD, Nutritional deficiency,

    Barretts esophagus, Poor oral hygiene, Cigarette smoking

    Adenocarcinoma squamous cellcarcinoma

    Cancer cell arise from the surface area of esophagus

    Chronic esophageal irritation/ tumor

    Dysphagia

    Sensation mass in throat

    Painful swallowingSubsternal pain or fullness

    Regurgitation of undigestive food

    Obstruction of esophagus

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    STAGING/GRADING

    Staging of squamous cell carcinoma of theesophagus

    Stage 0: This is the same as Tis cancer, in

    which cancer is found in only the top lining ofthe esophagus (Tis, N0, M0, G1)

    Stage IA: This is the same as T1 cancer, in

    which the cancer is located in only the twoinside layers of the esophagus. (T1, N0, M0,

    G1)

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    Stage IB: Either of these two conditions:

    The cancer is located in only the two inside

    layers of the esophagus, but the tumor cells

    are less differentiated (T1, N0, M0, G2 or G3)

    The tumor is located in the lower part of the

    esophagus, and the cancer has spread to

    either of the two outer layers of the

    esophagus, but not to the lymph nodes orother parts of the body. (T2 or T3, N0, M0,

    G1)

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    Stage IIA: Either of these two conditions:

    The tumor is located in the upper or middle

    part of the esophagus, and the cancer is ineither of the two outer layers of theesophagus. (T2 or T3, N0, M0, G1),

    The tumor is located in the lower part of theesophagus, and the cancer is in either of thetwo outer layers of the esophagus. The tumorcells are less differentiated. (T2 or T3, N0,

    M0, G2 or G3)

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    Stage IIB: Either of these two conditions:

    The tumor is located in the upper or middlepart of the esophagus, and cancer is in either

    of the two outer layers of the esophagus. The

    tumor cells are less differentiated. (T2 or T3,N0, M0, G2 or G3),

    Cancer is in the inner layers of the

    esophagus and has spread to one or twolymph nodes near the tumor. (T1 or T2, N1,

    M0, any G)

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    Stage IIIA: Any of these three conditions:

    Cancer is in the inner layers of the

    esophagus and has spread to three to six

    lymph nodes near the tumor. (T1 or T2, N2,

    M0, any G)

    Cancer is in the outside layer of the

    esophagus, with involvement of one or two

    lymph nodes. (T3, N1, M0, any G)

    Cancer has spread beyond the esophagus to

    nearby tissue, but no spread to lymph nodes

    or other areas of the body (T4a, N0, M0, any

    G)

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    Stage IIIB: Cancer is in the outside layer of theesophagus and in three to six lymph nodes. (T3,N2, M0, any G)

    Stage IIIC:Any of these three conditions: Cancer has spread beyond the esophagus into

    nearby tissue. Cancer is also in six or lesslymph nodes. (T4a, N1 or N2, M0, any G)

    Cancer has spread beyond the esophagus intonearby tissue, but cannot be removed bysurgery. (T4b, any N, M0, any G)

    Cancer involves seven or more lymph nodes,but has not spread to distant parts of the body.(any T, N3, M0, any G)

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    Stage IV: Cancer has spread to another partof the body (any T, any N, M1, any G)

    Staging of adenocarcinoma of theesophagus

    Stage 0: This is the same as Tis cancer, in

    which cancer is found in only the top lining ofthe esophagus (Tis, N0, M0, G1)

    Stage IA: This is the same as T1 cancer, in

    which the cancer is located in either of thetwo inside layers of the esophagus only. (T1,

    N0, M0, G1 or G2)

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    Stage IB: Either of these two conditions:

    The cancer is located in either of the two

    inside layers of the esophagus only, and the

    tumor cells are poorly differentiated (T1, N0,

    M0, G3),

    The cancer has spread to an outer layer of

    the esophagus, but not to the lymph nodes or

    other parts of the body. (T2, N0, M0, G1 or

    G2)

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    Stage IIA: Cancer is in an outer layer of theesophagus, and the cells are poorly

    differentiated. (T2, N0, M0, G3)

    Stage IIB: Either of these two conditions:

    Cancer is in the outside layer of theesophagus, but not beyond. (T3, N0, M0, any

    G)

    Cancer is in an inner layer or the muscularis

    propria of the esophagus, and involves one

    or two lymph nodes. (T1 or T2, N1, M0, any

    G).

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    Stage IIIA: Any of these three conditions:

    Cancer is in the inner layers of the

    esophagus and has spread to three to sixlymph nodes near the tumor. (T1 or T2, N2,M0, any G), or

    Cancer is in the outside layer of theesophagus, with involvement of one or twolymph nodes. (T3, N1, M0, any G), or

    Cancer has spread beyond the esophagus tonearby tissue, but there is no spread tolymph nodes or other areas of the body (T4a,N0, M0, any G)

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    Stage IIIB: Cancer is in the outside layer of theesophagus and in three to six lymph nodes. (T3,N2, M0, any G)

    Stage IIIC:Any of these three conditions: Cancer has spread beyond the esophagus into

    nearby tissue. Cancer is also in six or lesslymph nodes. (T4a, N1 or N2, M0, any G)

    Cancer has spread beyond the esophagus intonearby tissue, but cannot be removed bysurgery. (T4b, any N, M0, any G)

    Cancer involves seven or more lymph nodes,but has not spread to distant parts of the body.(any T, N3, M0, any G)

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    Stage IV: Cancer has spread to another partof the body (any T, any N, M1, any G)

    Recurrent: Recurrent cancer is cancer thatcomes back after treatment. It may come

    back in the esophagus or in another part of

    the body.

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    CLINICAL MANIFESTATION

    Many of patients have an advanced ulceration

    lesion of the esophagus before symptoms is

    manifested.

    Symptoms include dysphagia, initially solidfoods and eventually with liquids, a sensation of

    a mass in the throat, painful swallowing,

    substernal pain of fullness, and, later,regurgitation of undigested food with foul breath

    with hiccups.

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    The patient first becomes aware of

    intermittent and increasing difficulty in

    swallowing.As the tumor grows and the obstruction is

    nearly complete, even liquids cannot pass

    into the stomach.Regurgitation of food and saliva occurs,

    hemorrhage may take place, and the

    progresses loss weight and strengthoccurs from inadequate nutrition.

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    Later symptoms include substernal pain,

    persistent hiccup, respiratory difficulty, and

    foul breath.

    The delay between the onset of early

    symptoms and the patient seeking medical

    advice is often 12 to 18 months.

    Any person having difficulty swallowing

    difficulties should be encouraged toconsult physician immediately.

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    MEDICAL MANAGEMENT

    Treatment may include surgery, radiation,chemotherapy, or combination of thesemodalities depending on the type ofcancer cell, the extent of the disease, and

    the patient cancer includes the following:

    preoperative combination chemotherapyand radiation therapy for 4 to 6 weeks;

    followed by no medical intervention for 4weeks;

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    lastly surgeon resections of the

    esophagus.Standard surgical management includes

    the total resection of the esophagus

    (esophagectomy) with removal of tumorplus a wide tumor margin of the

    esophagus and the lympnodes in the area.

    The surgical approach maybe through the

    thorax or the abdomen, depending on the

    location of the tumor.

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    When the tumor occur in the cervical or

    upper thoracic area, esophageal

    continuity maybe maintained by a free

    jejuna graft transfer, in which the tumor

    removed and the area is replaced with a

    portion of jujenum.A segment of a colon maybe used, or the

    stomach can be elevated into the chest

    and the proximal section of the esophagusanastomosed to the stomach.

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    NURSING MANAGEMENT

    Assessment

    Asses the patient for backwards movement

    of food through the esophagus and possibly

    mouth (regurgitation), chest pain unrelated toeating difficulty swallowing solids or liquids,

    heartburn, vomiting blood, weight loss

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    Diagnosis

    Imbalanced nutrition, less than bodyrequirements, related to difficulty swallowing

    Risk for aspiration related to difficultyswallowing or to tube feeding

    Acute pain related to difficulty swallowing,ingestion of an abrasive agent, tumor, orfrequent episodes of gastric reflux

    Deficient knowledge about the esophageal

    disorder, diagnostic studies, medicalmanagement, surgical intervention, andrehabilitation

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    Planning

    The major goals for the patient mayinclude attainment of adequate nutritional

    intake, avoidance of respiratory

    compromise from aspiration, relief of pain,and increased knowledge level

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    Nursing Interventions

    Encouraging adequate nutritional intake

    Decreasing risk of infection

    Relieving pain Providing patient Education

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    ESOPHAGEAL

    CANCER

    PREPARED BY:

    CHARLES JO FRITZ MACALDEDOMINIC ROY PANES

    LONA GRACE TRIBUNSAY

    CHRISTY PADERNILLA

    SUBMITTED TO:

    MRS. FAITH FRANCES L. LIBARIOS, R.N.