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    Enhancing Information Pertaining to Client Characteristics

    to Facilitate Evidence-Based Practice

    Jennifer L. Callahan,1 Christopher J. Heath,1 Nicki L. Aubuchon-Endsley,2

    Frank L. Collins Jr.,1 and Gregory L. Herbert1

    1University of North Texas2Alpert Medical School of Brown University

    Objective: Evidence-based practice (EBP) includes utilization of empirically supported treatments,application of clinical expertise, and consideration of client characteristics. The following brief report

    aims to elucidate barriers in the study and dissemination of research regarding these client char-

    acteristics. Design: Authors examined empirical papers cited on psychologicaltreatments.org(N = 338) and categorized each according to efficacy evidence available pertaining to gender,

    race/ethnicity, and socioeconomic status (SES). Results: Gender was most commonly consid-ered (7% of studies), with less than 2% of studies analyzing efficacy in relation to race/ethnicity or

    SES. Conclusions: Available findings are summarized according to disorder. Researchers areencouraged to attend to client variables in efficacy studies and suggestions are offered for training

    students to include client variables in EBP. C 2013 Wiley Periodicals, Inc. J. Clin. Psychol. 00:125,

    2013.

    Keywords: evidence-based practice; client variables; psychological treatments; dissemination

    The evidence-based practice (EBP) movement dominates health care today and unites

    practitioners and clinical scientists in a range of health care disciplines. Psychologists have

    identified evidence-based psychological practice (EBPP) as the integration of the best available

    research with clinical expertise in the context of client characteristics, culture, and preferences

    (American Psychological Association [APA], 2005, p. 1). This approach sets a high bar forcompetent practice of professional psychology that serves to protect the public. The EBP

    movement is relatively recent, rooted in trends toward increasing accountability for medical

    outcomes in the United Kingdom (Wampold & Bhati, 2004).

    In the United States, EBP in psychotherapy first became salient during the 1990s with APAs

    Division 12 (Society of Clinical Psychology) Task Force on Promotion and Dissemination of

    Psychological Procedures (APA, 1993). The task force outlined the importance of identifying

    and utilizing Empirically Validated Psychological Treatments in addition to the effect of these

    treatments on clinician training and third-party payers. Though recent, the EBP movement is

    complicated and expansive. Thus, a comprehensive outline of its history is beyond the scope of the

    current article. However, the current article does address existing problems with dissemination

    of research on EBP (Addis, Wade & Hatgis, 2006; Gallo & Barlow, 2012; Kendall & Beidas,2007) specifically related to client variables within EBP.

    The facilitation of widespread application of EBP can be achieved only by careful management

    of evidence dissemination (McCabe, 2004), and many professional organizations are working

    towards this goal (McHugh & Barlow, 2010). Both the Substance Abuse and Mental Health

    Services Administration (SAMSHA) and Centers for Disease Control and Prevention (CDC)

    provide extensive information about their funded treatment projects. However, these sites are

    limited by not considering unfunded research.

    Further, the CDC website (http://www.cdc.gov/DiseasesConditions/) contains little infor-

    mation of use for mental health evidence dissemination, while the use of the Diagnostic and

    Please address correspondence to: Jennifer L. Callahan, Department of Psychology, University of NorthTexas, 1155 Union Circle #311280, Denton TX 76203-5017. E-mail: [email protected]

    *Posthumous.

    JOURNAL OF CLINICAL PSYCHOLOGY, Vol. 00(00), 125 (2013) C 2013 Wiley Periodicals, Inc.

    Published online in Wiley Online Library (wileyonlinelibrary.com/journal/jclp). DOI: 10.1002/jclp.21995

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    2 Journal of Clinical Psychology, XXX 2013

    Figure 1. The intersecting roles of research evidence, patient characteristics, and practitioner expertisein forming clinical decisions that characterize evidence-based practice within a given context (adaptedfrom Spring, B., Walker, B., Brownson, R., Mullen, E., Newhousc, R., et al. [July, 2008]. Defini-tion and competencies for evidence-based behavioral practice (EBBP). Retrieved from http://ebbp.org/documents/EBBP_Competcncies.pdf)

    Statistical Manual of Mental Disorders Fourth Edition (DSM-IV) diagnostic labels is limited on

    the SAMSHA website (http://www.nrepp.samhsa.gov/find.asp). The site allows for advanced

    search by client characteristics, which is commendable. APAs Division 12 has also organized

    evidence for dissemination on psychologicaltreatments.org. This website is organized by di-

    agnosis, citing hundreds of efficacy studies. It serves to identify the best available research

    evidence for common psychological disorders and explicitly reminds users that this evidence

    will necessarily be combined with clinician expertise and client values and characteristics in

    determining optimum approaches to treatment. However, accomplishing this integration ofeffective treatments, expertise, and client variables is challenging. Research consumers must de-

    cide what to read and whether findings should change their practice (Gross & Johnston, 2009;

    Stewart, Chambless, & Baron, 2012).

    Following these decisions, practitioners must use their clinical expertise to determine if ev-

    idence presented is relevant for particular individuals (Mazzucchelli & Sanders, 2010). As in

    Figure 1, EBP requires that clinical decisions incorporate the best available research evidence

    with client/population characteristics, state, needs, values, and preferences, and resources,

    including practitioner expertise.

    Therefore, to move toward EBP, we must also consider the relationship of client characteristics

    to treatment efficacy. In particular, prevalence rates for various mental health issues (e.g., Axis

    II disorders; Golomb, Fava, Abraham, & Rosenbaum, 1995) may be a function of gender.Psychopathology may also vary as a function of socioeconomic status (SES), ethnicity, and

    a range of other individual variables (Dohrenwend et al., 1992; Nguyen, Huang, Arganza, &

    Liao, 2007). A risk to successful delivery of EBP is to become focused on empirically supported

    treatments (ESTs) to an extent that important components of EBP are neglected. Although

    ESTs are important, they contribute only one component of EBP.

    The current article attempts to gather findings regarding individual differences and their

    effects on psychotherapy outcomes. Although knowing the answers to these questions would

    not address all components of EBP, it would move the discussion beyond a focus on treatment

    evidence towards comprehensive foreground questions that inform clinical practice with indi-

    viduals. This review examined accessible empirical studies cited on psychologicaltreatments.org

    to assist practitioners in responding to such foreground questions. Each study was consideredwith respect to gender, race/ethnicity, and SES, and those providing supporting evidence for

    treatment efficacy were summarized.

    Each study was examined to determine if there was: insufficient (not reported) informa-

    tion regarding client diversity; insufficient diversity (10% of reported N) but no corresponding efficacy

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    Facilitating EBP Via Information Disemmination 3

    analyses; inclusion of diversity in efficacy analyses with a finding of significant differences by

    group; or evidence that the treatment was equally effective (no significant group differences)

    for diverse clients. See Appendices for summary.

    Overall Patterns Observed in the Cited Studies

    Fully 93% (N= 315) of studies did not examine gender differences. Disorders that contained no

    cited gender difference studies included borderline personality disorder (BPD), generalized anx-

    iety disorder (GAD), obsessive-compulsive disorder (OCD), and specific phobia. Cited studies

    for BPD included only women. Citations for the remaining disorders described adequate gender

    representation to examine differences. The few studies examining differential treatment efficacy

    by gender report no significant differences (see Table A1). However, multicomponent cognitive-

    behavioral therapy for rheumatologic pain (Keefe et al., 1990a, 1990b) and reminiscence/life

    review therapy for depression (Fry, 1983) were more effective for women.

    Five studies addressed treatment efficacy as a function of race/ethnicity (1.5%; see Table A2).

    The Robinson-Wheelan et al. (2007) study results revealed that self-management/self-control

    therapy for depression was effective across groups. Similarly, efficacy of behavior ther-apy/behavior activation treatment of depression was found to be independent of race/ethnicity

    (Arean et al., 2005). With respect to schizophrenia, race/ethnicity did not significantly co-vary

    with treatment efficacy of cognitive adaptation training (Velligan et al., 2000; Velligan et al.,

    2002). Finally, Davidson and colleagues (2004) reported no differences in efficacy between Cau-

    casian and racial/ethnic minority clients for cognitive and behavioral therapy for social phobia.

    Few studies (N= 4; 1.2%), evaluated SES differences in treatment efficacy (see Table A3).

    No differences were found in family-focused therapy for bipolar disorder (Miklowitz, George,

    Richards, Simoneau, & Suddath, 2003), self-management / self-control therapy for depression

    (Robinson-Whelen, Hughes, Taylor, Hall, & Rehm, 2007), behavioral weight loss treatment

    for obesity and pediatric overweight (Israel, Silverman, & Solotar, 1986), or eye movement

    desensitization and reprocessing for posttraumatic stress disorder (PTSD; Wilson, Becker, &Tinker, 1995). Most studies were noted as containing insufficient information. Although many

    recent studies included information about education or employment status, this was not sufficient

    for characterizing SES.

    Disorder Specific Findings

    Tables A4 thru A16 provide details on all empirical studies cited on the Division 12 website,

    clustered into tables by disorder. Several listed disorders did not inform foreground questions.

    However, eight disorders included one or more treatment(s) that evaluated client characteristics,

    which are summarized below.

    Regarding bipolar disorder, differential prevalence rates have not been established based onrace, ethnicity, or gender although gender may play a role in the number, type, and onset of manic

    and major depressive episodes (American Psychiatric Association, 2000). Prevalence, however,

    does vary by age (6% of U.S. adults aged 1829 years, 5% aged 3044 years, 5% aged 4559 years,

    and 1% aged 60+ years; Kessler et al., 2005). Three studies from the website showed support

    of treatment efficacy independent of gender, including family-focused therapy (Miklowitz et al.,

    2003; Rea et al., 2003) and interpersonal and social rhythm therapy (Frank et al., 2005). Most

    studies (18 of 21 studies; 86%) failed to examine gender differences, examined one gender, or

    provided insufficient information in the methods to provide support. One study showed support

    independent of SES (family-focused therapy; Miklowitz et al., 2003) and no studies addressed

    race/ethnicity.

    Depression prevalence varies by gender (70% more likely in women), race (40% more likelyin White, non-Hispanic individuals than Black, non-Hispanic individuals), and age (9% of U.S.

    adults aged 1825 years, 7% aged 2649 years, and 5% aged 50+ years; Kessler et al., 2005).

    Several studies found support for treatment of Depression independent of gender, including

    behavior therapy/behavioral activation (Arean et al., 2005; Hopko, Lejuez, Lepage, Hokpo,

    & McNeil, 2003), cognitive behavioral analysis system of psychotherapy (Klein et al., 2004;

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    Manber et al., 2003), interpersonal therapy (Reynolds et al., 1999), problem-solving therapy

    (Reynolds et al., 1999), self-management/self-control therapy (Rokke, Tomhave, & Jocic, 2000),

    and behavioral couple therapy (Christensen, Atkins, Yi, Baucom, & George, 2006).

    As noted above, reminiscence/life review therapy found greater efficacy for women. Only two

    treatments, behavior therapy/behavior activation (Arean et al., 2005) and self-management/self-

    control therapy (Robinson-Whelen et al., 2007) examined race/ethnicity influences on treatmentefficacy. Both studies found treatment to be equally effective for Caucasian and ethnic minority

    clients. Self-management/self-control therapy (Robinson-Whelen et al., 2007) was also found to

    be equally effective regardless of SES.

    Eating disorder prevalence varies by demographic characteristics depending on the specific

    disorder. Prevalence of anorexia nervosa, bulimia nervosa, and binge eating disorder is two to

    three times greater in women and more likely in industrialized societies (Hudson, Hiripi, Pope, &

    Kessler, 2007). Although the incidence of anorexia nervosa does not appear to vary by age, those

    younger than 60 years of age are significantly more to develop bulimia nervosa and binge eating

    disorder compared with other age groups (Hudson et al., 2007). Studies supported behavioral

    weight loss for obesity and pediatric overweight as equally effective across gender (Tuomilehto

    et al., 2001; Wing, Blair, Marcus, Epstein, Harvey, 1994) and not differentially influenced byparental SES (Israel et al., 1986).

    EMG biofeedback was found to be equally effective for insomnia in women and men

    (Barrowsky, Moskowitz, & Zweig, 1990), despite a greater prevalence of the disorder in women.

    Psychoanalytic treatment for panic disorder was also equally effective for both women and men,

    though there is a greater incidence of diagnosis in women (Milrod et al., 2007). Eye movement

    desensitization and reprocessing therapy for PTSD was equally effective across gender and SES

    categories (Wilson et al., 1995). Cognitive adaptation training for schizophrenia was equally

    effective for men and women, independent of race/ethnicity (Velligan et al., 2000; Velligan

    et al., 2002), although it is manifested differently by gender. Treatment effects were independent

    of gender and race/ethnicity for cognitive and behavioral therapy for social phobia (Davidson

    et al., 2004) and independent of gender for cognitive therapy (Clark et al., 2003), even thoughSocial Phobia is more common in women.

    Discussion

    The goal of the current study was to assist practitioners as they aim to provide high quality

    EBP. However, as we carried out the study, we came to more fully appreciate the frequent lack

    of consideration of client characteristics by researchers studying treatment efficacy. Overall,

    evidence for treatment efficacy rarely addresses foreground questions of gender, race/ethnicity,

    or SES. This is unfortunate as client variables reflect a range of factors contributing to individ-

    ual uniqueness. Such variables may include the clients presenting problems (e.g., variations in

    etiology, symptoms, behavior, etc.), views of treatment (e.g., readiness to change, preferences,expectations, etc.), sociocultural and familial factors (e.g., religion, values, beliefs, etc.), environ-

    mental factors (e.g., employment, major life events, etc.), or other factors like age or development

    level (APA, 2006).

    While research indicates that client characteristics play an important role in treatment out-

    comes (see Clarkin & Levy, 2004; Zane, Sue, Young, Nunez, & Hall, 2004) and should be

    incorporated in EBP to treat individuals (Beutler, Forrester, Gallagher-Thompson, Thompson,

    & Tomlins, 2012), the tables provided in Appendices support that client variables are frequently

    overlooked in research. It is not possible to determine from these data whether practitioners also

    overlook these variables. In the absence of such information, it may be helpful for practitioners

    to keep in mind a few easily recalled findings from broad psychotherapy literature that are not

    evident from studies considered in this review.

    Client Variables in the Broad Literature

    Age and gender. Consideration of client characteristics reveals that, among adults, ageis not strongly related to treatment retention or outcome in the broad psychotherapy literature

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    (Dubrin & Zastowny, 1988; Sledge, Moras, Hartley, & Levine, 1990). Although, more recently it

    has been reported that younger individuals are more likely to have used mental health services and

    report greater likelihood of using such services in the future (Smith, Peck, & McGovern 2004).

    Similarly, research generally reveals no gender differences in therapy outcome in adults

    (Garfield, 1994; Petry, Tennen, & Affleck, 2000), with some exceptions pertaining to treat-

    ment for depression (Thase, Frank, Kornstein, & Yonkers, 2000) or substance abuse disorders(Blood & Cornwall, 1994; Rivers, Greenbaum, & Goldberg, 2001). Recent reports do indicate

    that gender may influence clients willingness to initiate treatment and evaluation of treatment

    options (Green, Polen, Dickinson, Lynch, & Bennett, 2002; Smith, Peck, & McGovern, 2004).

    Race and ethnicity. For racial and ethnic minority clients, research suggests that theworking alliance (connection between client and practitioner with respect to goals, tasks, and

    bond; Gelso & Hayes, 1998) may be especially important in fostering positive outcomes, and

    some approaches may foster more positive alliances (e.g., Duan & Wang, 2000; Ortega & Alegra,

    2002; Wong, Kim, & Zane, 2003). Other research suggests that the impact of therapist attitude

    on treatment outcomes might be related to SES, rather than ethnicity (Lerner, 1972).

    Demeanor. Beyond demographics, it is also important in EBP to consider client variableslike demeanor and preferences. Thornton et al. (2003) reported that behaviorally oriented,

    structured treatments worked better with clients who had a helpless demeanor, while a less

    structured, facilitative treatment milieu was found to be more efficacious for others.

    Preferences. Swift and Callahan (2009) conducted a meta-analytic review summarizingdata from 26 studies including 2,300 clients and found that those who received preferred treat-

    ment were half as likely to drop out and had a 58% chance of showing greater improvement.

    They also found that study design served as a moderator, causing partially randomized pref-

    erence trials to likely underestimate the effect of client treatment preferences. A subsequent

    meta-analysis (Swift, Callahan, & Vollmer, 2011) replicated this finding. Meta-regression of thisdata found that client preferences are important to all clients, regardless of age, gender, ethnicity,

    educational level, or marital status (Swift, Callahan, Ivanovic, & Kominiak, 2013).

    The current article illustrates the dearth of research related to the influence of client

    variables on treatment outcomes. The information presented is often characterized by false

    dichotomies (e.g., ethnicity treated as Caucasian/not Caucasian). Additionally, gender is

    presented as dichotomous despite evidence that this construct may not accurately reflect gender

    identity (Lorber, 1995). These dichotomies prevent a nuanced understanding of the literature

    and reflect difficulties in collecting representative samples. Increased understanding of these

    non-dichotomous constructs will allow for more clinically applicable findings in research. The

    efficacy of a psychological treatment with any given individual is even far more complicated.

    The requirement of clinical expertise in true EBP underscores the challenge in competentlybridging the nomothetic-idiographic divide when engaged in professional practice. Although

    consideration of clinical expertise variables in EBP is beyond the scope of this review (though

    we encourage this to complement the existing Division 12 website and the current study tables in

    appendices), we wish to conclude by offering a few suggestions on training of students in EBP.

    Promoting Client Variables During Training in EBP

    Training students to integrate client variables into EBP can be challenging because they often are

    highly desirous of learning ESTs and are prone to mistakenly conclude that using an EST is EBP.

    The lack of attention to client variables in the cited studies on the psychologicaltreatments.org

    website may inadvertently reinforce the mistaken perception by students that use of an EST is

    EBP. This lack of distinction between EST and EBP may not be unique to students.A number of studies and literature reviews substitute the term evidence-based practice with

    other terms (e.g., Chambless & Ollendick, 2001), thereby possibly adding to definitional confu-

    sion. Westen and colleagues (Westen, Novotnoy & Thompson-Brenner, 2004; Westen & Bradley,

    2005) highlight that although ESTs are often seen as the fundamental basis of EBP, they com-

    prise only one component of EBP. This ignores other aspects of psychotherapy practice and

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    research that contribute to EBP such as common factors (Wampold & Bhati, 2004) and client

    treatment preferences (Swift & Callahan, 2009). True adherence to EBP guidelines must account

    for these and other research/factors in treatment provision, which should also be incorporated

    into training (Spring, 2007).

    Aside from encouraging a range of practicum experiences that bring students into contact

    with a variety of clients from diverse backgrounds, characteristics, values, and preferences, wesuggest formal instruction in shared decision-making in clinical practice (Adams & Drake,

    2006). A collaborative interaction between therapist and client should be emphasized with both

    influencing treatment decisions (Beutler et al., 2012; Ford, Schofield, & Hope, 2003).

    Four components are inherent to successful application of the shared decision-making model:

    (a) two parties are involved, (b) both share information, (c) both discuss preferences for treat-

    ment, and (d) an agreement is reached as to implement treatment (Charles, Whelan, Gafni,

    Willan, & Farrell, 2003). The use of a shared decision-making model coupled with diverse

    practicum experiences may further trainee development in EBP. Practicum supervisors are

    strongly encouraged to routinely discuss client and trainee values, preferences, goals, plans,

    progress, etc., during supervision, especially when treatment decisions are considered. In con-

    trast, supervisors are discouraged from simply monitoring treatment adherence (an importantpart of effective EST supervision) as the sole indicator of EBP.

    Promoting Client Variables With Lifelong Learning in EBP

    EBP also requires lifelong learning via consumption of research (Spring, 2007). To facilitate this,

    we suggest that practitioners specifically attend to client characteristics information as research

    consumers. Lifelong learning could be promoted by encouraging future research regarding EPBs

    at the division, professional societies, and other levels. Additionally, dissemination of updates

    to research in EBPs should be encouraged at conferences in addition to associated clinical

    trainings. It is also vital to recognize that publication bias limits dissemination of psychotherapy

    research (Song et al., 2010), suggesting that greater emphasis on null or unpublished findingsmay be particularly helpful. In particular, research consumers and reviewers should encourage

    investigators to publish their broad range of findings.

    Finally, with respect to dissemination efforts, organizations should include pertinent client

    information (e.g., Division 12 could add a section to each disorders page) or create dynamic

    websites that allow for searching according to client characteristics or embed within sites the

    necessary programming code to open and simultaneously search other databases.

    In sum, the lack of research addressing the effect of client variables currently prevents reliably

    generalizable conclusions being drawn from papers reviewed. The dearth of investigation into

    these variables is therefore identified as a vital area for growth within the larger sphere of

    psychotherapy research.

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    Appendix

    Table A1Gender

    Bipolar disorder 3 0 16 1 1

    BDP 0 0 0 8 0

    Chronic pain 0 2 11 2 0

    Depression 8 1 35 10 1Eating disorders 2 0 30 58 7

    GAD 0 0 9 0 1

    Insomnia 1 0 16 1 0

    OCD 0 0 6 0 1

    Panic 1 0 5 0 0

    PTSD 1 0 2 12 0

    Schizophrenia 2 0 26 5 2

    Social phobia 2 0 18 1 2

    Specific phobia 0 0 19 6 3

    Notes. N= 338; Evidence for each group; Analyzed subgroups; Sufficient N, no analysis;

    Insufficient N, < 10%; Insufficient information reported.BPD= borderline personality disorder; GAD= generalized anxiety disorder; OCD= obsessive-compulsive

    disorder; PTSD = posttraumatic stress disorder.

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    Table A2Race/Ethnicity

    Bipolar disorder 0 0 6 4 11

    BDP 0 0 3 1 4

    Chronic pain 0 0 1 1 13

    Depression 2 0 19 13 21

    Eating disorders 0 0 30 16 51

    GAD 0 0 1 2 7

    Insomnia 0 0 3 2 13

    OCD 0 0 0 1 6

    Panic 0 0 2 1 3

    PTSD 0 0 9 2 4

    Schizophrenia 2 0 16 2 15

    Social phobia 1 0 3 2 17

    Specific phobia 0 0 2 1 25

    Notes. N= 338; Evidence for each group; Analyzed subgroups; Sufficient N, no analysis;

    Insufficient N, < 10%; Insufficient information reported.

    BPD= borderline personality disorder; GAD= generalized anxiety disorder; OCD= obsessive-compulsive

    disorder; PTSD = posttraumatic stress disorder.

    Table A3SES

    Bipolar disorder 1 0 5 0 15

    BDP 0 0 2 0 6

    Chronic pain 0 0 1 0 14

    Depression 1 0 3 2 49

    Eating disorders 1 0 9 0 87

    GAD 0 0 0 0 10

    Insomnia 0 0 0 0 18

    OCD 0 0 0 0 7

    Panic 0 0 0 0 6

    PTSD 1 0 6 0 8

    Schizophrenia 0 0 3 4 28

    Social phobia 0 0 2 0 21

    Specific phobia 0 0 2 0 26

    Notes. N = 338; Evidence for each group; Analyzed subgroups; Sufficient N, no analysis;

    Insufficient N, < 10%; Insufficient information reported.

    BPD= borderline personality disorder; GAD= generalized anxiety disorder; OCD= obsessive-compulsive

    disorder; PTSD = posttraumatic stress disorder.