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EMC COEUR-09 - Cardiovascular Research School Erasmus MC Rotterdam.

Programme in brief design 1. Cardiovascular Biology and Pharmacology

Molecular basis, pathophysiology and therapy of obstructive coronary artery disease, cardiac and coronary remodelling and heart failure

2. Vascular Medicine Hemostasis and Stroke The clinical complement to the previous theme. Cardiovascular genetics, blood pressure regulation and vascular medicine, thrombotic and bleeding disorders, acute and chronic cardiovascular disease

3. Image-guided Cardiovascular Medicine Fundamental and clinical research of novel diagnostic imaging modalities

4. Surgical- Interventional and Device Therapy of Cardiovascular Disease Clinical application and implementation of new diagnostic and therapeutic techniques. Local drug delivery cell therapy vascular interventions and other device therapy

5. Congenital Heart Disease Small but important theme focussing on major structural congenital cardiac abnormalities and their management

6. Neurovascular and Cardiovascular Clinical Epidemiology Risk modelling rational, predictive thinking and implementation of appropriate diagnostic and therapeutic measures across a wide range of clinical cardiovascular syndromes and procedures.

Key figures Department SP1 SP2 SP3 SP4 Sptot T1 T2 T3 Ttot IS FS OP Ptot anesthesiology 2,18 1,47 0 4,72 8,37 biostatistics 0,4 0 0 0 0,4 cardiac surgery 8,57 2,4 0 0,8 11,77 cardiology 26,82 0,9 0,45 1,3 29,47 epidemiology 0 0 0 0,5 0,5 gynaecology/obstetrics 0,3 0 0 0 0,3 hematology 0,48 0 1 2,8 4,28 internal medecine 7,94 0 4,15 4,66 16,75 neurology 3,35 4 1,4 1,38 10,13 pediatrics-cardiology 1 0 0 0 1 pediatrics-other 0 0 3 0 3 radiology 1,36 0 0 0 1,36 Total 52,4 8,77 10 16,16 87,33 26 0 0 26 459 79 17 581

Thesis Belle, Y.L.E. van (2010, november 25). Cryballoon pulmonary vein isolation for the treatment of atrial fibrillation and issues in

follow-up management. EUR. Prom./coprom.: Prof. Dr. L.J.L.M. Jordaens. Bongers, T.N. (2010, december 09). ADAMTS13 in arterial thrombosis. EUR (160 pag.). Prom./coprom.: Prof. Dr. F.W.G.

Leebeek.

Brugts, J.J. (2010, februari 17). Tailored-therapy of ACE-inhibitors in coronary artery disease. EUR. Prom./coprom.: Prof. Dr. M.L. Simoons & Prof. Dr. Ir. E. Boersma.

Buise, M.M. (2010, september 30). Gastric microcirculation and respiratory morbidity following esophagectomy. EUR.

Prom./coprom.: Prof. Dr. R.J. Stolker & prof.dr. A.A.J. van Zundert. Dehghan, A. (2010, maart 31). Novel risk factors for type II diabetes mellitus and coronary heart disease. EUR. Prom./coprom.:

Prof. Dr. J.C.M. Witteman & Prof. Dr. E.J.G. Sijbrands. Flu, W.J.P. (2010, juni 09). Symptomatic atherosclerosis - the tip of the iceberg. EUR. Prom./coprom.: Prof. Dr. D. Poldermans. Galema, T.W. (2010, juni 30). Improved imaging in cardiac patients: echocardiography and CT-coronary angiography. EUR.

Prom./coprom.: Prof. Dr. M.L. Simoons. Gameren, M. van (2010, november 10). Risk stratification and outcome assessment in cardiac surgery and transcatheter

interventions. EUR (281 pag.). Prom./coprom.: Prof. Dr. A.J.J.C. Bogers. Gestel, Y.R.B.M. van (2010, maart 24). Chronic obstructive pulmonary disease in patients with atherosclerosis. EUR.

Prom./coprom.: Prof. Dr. D. Poldermans. Giessen, A.G. van der (2010, juni 25). Coronary atherosclerosis and wall shear stress. EUR. Prom./coprom.: Prof. Dr. Ir. A.F.W.

van der Steen & Prof.Dr. P.J. de Feyter. Gonzalo Lopez, M.N. (2010, februari 03). Optical coherence tomography for the assessment of coronary atherosclerosis and

vessel response after stent implantation. EUR. Prom./coprom.: Prof.Dr. P.W.J.C. Serruys.

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Herpers, R.L.J.M. (2010, maart 31). Genetic regulation of vascular development. EUR. Prom./coprom.: Prof. Dr. D.J.G.M. Duncker & S Schulte-Merker.

Hoeks, S.E. (2010, februari 12). Perioperative cardiac care: from guidelines to clinical practice. EUR. Prom./coprom.: Prof. Dr.

D. Poldermans. Hoekstra, J. (2010, december 17). Etiology and clinical outcome of Budd-Chiari syndrome and portal vein thrombosis. EUR (179

pag.). Prom./coprom.: Prof. Dr. H.L.A. Janssen & Prof. Dr. F.W.G. Leebeek. Jansen, T.C. (2010, juni 18). Lactate monitoring in critically ill patients. EUR. Prom./coprom.: Prof. Dr. J. Bakker. Kuijk, J.P. van (2010, september 15). Polyvascular atherosclerotic disease. EUR. Prom./coprom.: Prof. Dr. D. Poldermans. Lipton, J.A. (2010, oktober 13). Improving quality of care in acute cardiology. EUR. Prom./coprom.: Prof. Dr. M.L. Simoons. Matte, G. (2010, november 25). Exploiting ultrasound harmonics. EUR. Prom./coprom.: Prof.dr.ir. N. de Jong & Prof. Dr. Ir.

A.F.W. van der Steen. Neer, P.L.M.J. van (2010, juli 01). Ultrasonic superharmonic imaging. EUR. Prom./coprom.: Prof. Dr. Ir. A.F.W. van der Steen &

Prof.dr.ir. N. de Jong. Patterson, M.S. (2010, juni 29). Magnetic navigation in percutaneous cardiac intervention. EUR. Prom./coprom.: Prof.Dr.

P.W.J.C. Serruys. Rutten, J.H.W. (2010, november 23). Natriuretic peptides, diagnostic and prognostic markers. EUR. Prom./coprom.: Prof. Dr.

A.H.J. Danser & A.H. van den Meiracker. Tanimoto, S. (2010, februari 03). Drug eluting stent implantation for high risk patients and novel technologies in percutaneous

coronary intervention. EUR. Prom./coprom.: Prof.Dr. P.W.J.C. Serruys & A.G. van der Giessen. Vidakovic, R. (2010, januari 13). Polyvascular athrosclerosis - diagnostic and prognostic burden. EUR. Prom./coprom.: Prof. Dr.

D. Poldermans. Vos, H.J. (2010, januari 20). Single microbubble imaging. EUR. Prom./coprom.: Prof. Dr. Ir. A.F.W. van der Steen & Prof.dr.ir. N.

de Jong. Weustink, A.C. (2010, december 15). CT coronary angiography in clinical practice. EUR (269 pag.). Prom./coprom.: Prof.Dr.

P.J. de Feyter, Prof. Dr. G.P. Krestin & Dr. N.R.A. Mollet. Winkel, T.A. (2010, september 29). How to reveal arrhythmias in vascular surgery patients. EUR. Prom./coprom.: Prof. Dr. D.

Poldermans. .

Artikel/Letter to the editor Akdim, F, Stroes, ESG, Sijbrands, E.J.G., Tribble, DL, Trip, M.D., Jukema, J.W., Flaim, JD, Su, J, Yu, R, Baker, BF, Wedel, MK

& Kastelein, J.J.P. (2010). Efficacy and Safety of Mipomersen, an Antisense Inhibitor of Apolipoprotein B, in Hypercholesterolemic Subjects Receiving Stable Statin Therapy. Journal of the American College of Cardiology, 55(15), 1611-1618.

Alberts, VP, Bos, M.J., Koudstaal, P.J., Hofman, A., Witteman, J.C.M., Stricker, B.H.C. & Breteler, M.M.B. (2010). Heart failure

and the risk of stroke: the Rotterdam Study. European Journal of Epidemiology, 25(11), 807-812. Allessie, MA, Groot, N.M.S. de, Houben, RPM, Schotten, U, Boersma, E., Smeets, JL & Crijns, HJ (2010). Electropathological

Substrate of Long-Standing Persistent Atrial Fibrillation in Patients With Structural Heart Disease. Circulation-arrhythmia and electrophysiology, 3(6), 606-615.

Altindag, T., Roos-Hesselink, J.W., Cuypers, J.A.A.E., Domburg, R.T. van, Jaegere, P.P.T. de, Meijboom, F.J. & Witsenburg, M.

(2010). Transcatheter device closure of atrial septal defects in patients aged 40 years and older. Cardiologie (Hoogland), 18(11), 537-542.

Antoni, ML, Bertini, M, Atary, JZ, Delgado, V, Brinke, EA ten, Boersma, E., Holman, E.R., Wall, E.E. van der, Schalij, M.J., Bax,

J.J. & Veire, NRL van de (2010). Predictive Value of Total Atrial Conduction Time Estimated With Tissue Doppler Imaging for the Development of New-Onset Atrial Fibrillation After Acute Myocardial Infarction. American Journal of Cardiology, 106(2), 198-203.

Antoni, ML, Mollema, SA, Delgado, V, Atary, JZ, Borleffs, CJW, Boersma, E., Holman, E.R., Wall, E.E. van der, Schalij, M.J. &

Bax, J.J. (2010). Prognostic importance of strain and strain rate after acute myocardial infarction. European Heart Journal, 31(13), 1640-1647.

Antoni, ML, Scherptong, RWC, Atary, JZ, Boersma, E., Holman, E.R., Wall, E.E. van der, Schalij, M.J. & Bax, J.J. (2010). Prognostic Value of Right Ventricular Function in Patients After Acute Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention. Circulation Cardiovascular Imaging, 3(3), 264-271.

Antoni, ML, Mollema, SA, Atary, JZ, Borleffs, CJW, Boersma, E., Veire, NRL van de, Holman, E.R., Wall, E.E. van der, Schalij,

M.J. & Bax, J.J. (2010). Time course of global left ventricular strain after acute myocardial infarction. European Heart Journal, 31(16), 2006-2013.

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Anttila, V, Stefansson, H, Kallela, M, Todt, U, Terwindt, G.M., Calafato, MS, Nyholt, DR, Dimas, AS, Freilinger, T, Muller-Myhsok, B, Artto, V, Inouye, M, Alakurtti, K, Kaunisto, MA, Hamalainen, E, Vries, B de, Stam, AH, Weller, CM, Heinze, A, Heinze-Kuhn, K, Goebel, I, Borck, G, Gobel, H, Steinberg, S, Wolf, C, Bjornsson, A, Gudmundsson, G, Kirchmann, M, Hauge, A, Werge, T, Schoenen, J., Eriksson, JG, Hagen, K, Stovner, L, Wichmann, E, Meitinger, T, Alexander, M, Moebus, S, Schreiber, S., Aulchenko, Y.S., Breteler, M.M.B., Uitterlinden, A.G., Hofman, A., Duijn, C.M. van, Tikka-Kleemola, P, Vepsalainen, ., Lucae, S, Tozzi, F, Muglia, P, Barrett, J, Kaprio, J, Farkkila, M, Peltonen, L., Stefansson, K, Zwart, JA, Ferrari, M.D., Olesen, J, Daly, M., Wessman, M, Maagdenberg, A.M.J.M., Dichgans, M, Kubisch, C, Dermitzakis, ET, Frants, R.R. & Palotie, A (2010). Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nature Genetics, 42(10), 869-873.

Anwar, A.M., Attia, WM, Nosir, Y.F.M., Soliman, O.I.I., Mosad, MA, Othman, M, Geleijnse, M.L., El-Amin, AM & Cate, F.J. ten

(2010). Validation of a New Score for the Assessment of Mitral Stenosis Using Real-Time Three-Dimensional Echocardiography. Journal of the American Society of Echocardiography, 23(1), 13-22.

Arts, C.H., Verhagen, H.J.M., Heyligers, J.M., Moll, F.L. & Poldermans, D. (2010). Treatment of acute aortic dissection type B.

Nederlands Tijdschrift voor Geneeskunde, 154(1), 460. Auger, D, Bommel, RJ van, Bertini, M, Delgado, V, Ng, ACT, Ewe, SH, Shanks, M, Marsan, NA, Mooyaart, EAQ, Witkowski, T,

Poldermans, D., Schalij, M.J. & Bax, J.J. (2010). Prevalence and characteristics of patients with clinical improvement but not significant left ventricular reverse remodeling after cardiac resynchronization therapy. American Heart Journal, 160(4), 737-743.

Baeten, S.A., Exel, N.J.A. van, Dirks, M., Koopmanschap, M.A., Dippel, D.W.J. & Niessen, L.W. (2010). Lifetime health effects

and medical costs of integrated stroke services - a non-randomized controlled cluster-trial based life table approach. Cost Effectiveness and Resource Allocation, 8(21), 1-10.

Bakker, J.F., Paulides, M.M., Christ, A, Kuster, N & Rhoon, G.C. van (2010). Assessment of induced SAR in children exposed to

electromagnetic plane waves between 10 MHz and 5.6 GHz. Physics in Medicine and Biology, 55(11), 3115-3130. Bakker, J.F., Paulides, M.M., Westra, A.H., Schippers, H. & Rhoon, G.C. van (2010). Design and test of a 434 MHz multi-

channel amplifier system for targeted hyperthermia applicators. International Journal of Hyperthermia, 26(2), 158-170. Banning, AP, Westaby, S, Morice, M.C., Kappetein, A.P., Mohr, FW, Berti, S, Glauber, M, Kellett, MA, Kramer, RS, Leadley, K,

Dawkins, KD & Serruys, P.W.J.C. (2010). Diabetic and Nondiabetic Patients With Left Main and/or 3-Vessel Coronary Artery Disease Comparison of Outcomes With Cardiac Surgery and Paclitaxel-Eluting Stents. Journal of the American College of Cardiology, 55(11), 1067-1075.

Bardy, GH, Smith, WM, Hood, MA, Crozier, IG, Melton, IC, Jordaens, L.J.L.M., Theuns, D.A.M.J., Park, RE, Wright, DJ,

Connelly, DT, Fynn, SP, Murgatroyd, FD, Sperzel, J, Neuzner, J, Spitzer, SG, Ardashev, AV, Oduro, A, Boersma, L., Maass, AH, Gelder, I.C. van, Wilde, AA, Dessel, PF van, Knops, RE, Barr, CS, Lupo, P, Cappato, R & Grace, AA (2010). An Entirely Subcutaneous Implantable Cardioverter-Defibrillator. New England Journal of Medicine, 363(1), 36-44.

Barlis, P., Regar, E.S., Serruys, P.W.J.C., Dimopoulos, K, Giessen, W.J. van der, Geuns, R.J.M. van, Ferrante, G, Wandel, S,

Windecker, S., Es, G.A. van, Eerdmans, P, Juni, P & Mario, C. di (2010). An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study. European Heart Journal, 31(2), 165-176.

Barry, M.C., Hendriks, J.M., Dijk, L.C. van, Pattynama, P.M.T., Poldermans, D., Hayes, DB, Urk, H. van & Sambeek, M.R.H.M.

van (2010). A comparative study of myocardial injury during conventional and endovascular aortic aneurysm repair: measurement of cardiac troponin T and plasma cytokine release. Irish Journal of Medical Science, 179(1), 35-42.

Bartorelli, A.L., Serruys, P.W.J.C., Miquel-Hebert, K, Yu, S, Pierson, W & Stone, G.W. (2010). An Everolimus-Eluting Stent

Versus a Paclitaxel-Eluting Stent in Small Vessel Coronary Artery Disease: A Pooled Analysis from the SPIRIT II and SPIRIT III Trials. Catheterization and Cardiovascular Interventions, 76(1), 60-66.

Bastos Goncalves, F.M., Metz, R., Hendriks, J.M., Rouwet, E.V., Muhs, BE, Poldermans, D. & Verhagen, H.J.M. (2010).

Decision-making in type-B dissection: current evidence and future perspectives. Journal of Cardiovascular Surgery, 51(5), 657-667.

Bastos Goncalves, F.M., Rouwet Ellen, V, Metz, R., Hendriks, J.M., Vrancken Peeters, M.P.F.M., Muhs, BE & Verhagen, H.J.M.

(2010). Device-specific outcomes after endovascular abdominal aortic aneurysm repair. Journal of Thoracic and Cardiovascular Surgery, 51(4), 515-531.

Batenburg, W.W. & Danser, A.H.J. (2010). De (pro)renine receptor: een nieuwe component van het renine-angiotensine systeem. Hart bulletin, 41, 149-152.

Bauer, T, Mollmann, H, Weidinger, F, Zeymer, U., Seabra-Gomes, R., Eberli, F, Serruys, P.W.J.C., Vahanian, A., Silber, S.,

Wijns, W., Hochadel, M, Nef, HM, Hamm, C.W., Marco, J. & Gitt, A.K. (2010). Use of platelet glycoprotein IIb/IIIa inhibitors in diabetics undergoing PCI for non-ST-segment elevation acute coronary syndromes: impact of clinical status and procedural characteristics. Clinical Research in Cardiology, 99(6), 375-383.

Bauernfeind, T., Caliskan, K., Kardos, A., Balk, A.H.M.M., Jordaens, L.J.L.M. & Szili-Torok, T. (2010). Double intra-atrial

connections in a patient late after orthotopic heart transplantation. Journal of Heart and Lung Transplantation, 29(6), 700-703. Bayard, YL, Omran, H, Neuzil, P, Thuesen, L., Pichler, M. von, Rowland, E, Ramondo, A, Ruzyllo, W., Budts, W, Montalescot,

G., Brugada, P, Serruys, P.W.J.C., Vahanian, A., Piechaud, J.F., Bartorelli, A, Marco, J., Probst, P., Kuck, KH, Ostermayer, SH, Buscheck, F, Fischer, E., Leetz, M & Sievert, H. (2010). PLAATO (Percutaneous Left Atrial Appendage Transcatheter

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Occlusion) for prevention of cardioembolic stroke in non-anticoagulation eligible atrial fibrillation patients: results from the European PLAATO study. EuroIntervention, 6(2), 220-226.

Beer, V.J. de, Graaff, H.J.D. de, Hoekstra, M., Duncker, D.J.G.M. & Merkus, D. (2010). Integrated control of pulmonary vascular

tone by endothelin and angiotensin II in exercising swine depends on gender. American Journal of Physiology-Heart and Circulatory Physiology, 298(6), H1976-H1985.

Bekkers, J.A., Klieverik, L.M.A., Bol Raap, G., Takkenberg, J.J.M. & Bogers, A.J.J.C. (2010). Aortic root reoperations after

pulmonary autograft implantation. Journal of Thoracic and Cardiovascular Surgery, S58-S63. Bender, S.B., Houwelingen, M.J. van, Merkus, D., Duncker, D.J.G.M. & Laughlin, MH (2010). Quantitative analysis of exercise-

induced enhancement of early- and late-systolic retrograde coronary blood flow. Journal of Applied Physiology, 108(3), 507-514. _ Berg, J.M. van den, Hof, A.W.J. van 't, Dill, T, Heestermans, T, Werkum, JW van, Mosterd, A., Houwelingen, G van, Koopmans,

PC, Stella, PR, Boersma, E. & Hamm, C. (2010). Effect of Early, Pre-Hospital Initiation of High Bolus Dose Tirofiban in Patients With ST-Segment Elevation Myocardial Infarction on Short- and Long-Term Clinical Outcome. Journal of the American College of Cardiology, 55(22), 2446-2455.

Bertrand, M.E., Ferrari, R., Remme, W.J., Simoons, M.L., Deckers, J.W. & Fox, K.M. (2010). Clinical synergy of perindopril and

calcium-channel blocker in the prevention of cardiac events and mortality in patients with coronary artery disease. Post hoc analysis of the EUROPA study. American Heart Journal, 159(5), 795-802.

Beusekom, H.M.M. van & Serruys, P.W.J.C. (2010). Drug-Eluting Stent Endothelium Presence or Dysfunction. JACC-

Cardiovascular interventions, 3(1), 76-77. Beusekom, H.M.M. van, Sorop, O, Heuvel, M. van den, Onuma, Y, Duncker, D.J.G.M., Danser, A.H.J. & Giessen, W.J. van der

(2010). Endothelial function rather than endothelial restoration is altered in paclitaxel- as compared to bare metal-, sirolimusand tacrolimus-eluting stents. EuroIntervention, 6(1), 117-125.

Bezemer, R, Klijn, E., Khalilzada, M, Lima, A. de, Heger, M, Bommel, J. van & Ince, C. (2010). Validation of near-infrared laser

speckle imaging for assessing microvascular (re)perfusion. Microvascular Research, 79(2), 139-143. Bikker, I.G., Leonhardt, S., Reis Miranda, D., Bakker, J. & Gommers, D. (2010). Bedside measurement of changes in lung

impedance to monitor alveolar ventilation in dependent and non-dependent parts by electrical impedance tomography during a positive end-expiratory pressure trial in mechanically ventilated intensive care unit patients. Critical Care, 14(3), R100.

Birim, O., Bogers, A.J.J.C. & Kappetein, A.P. (2010). Cost effectiveness of coronary revascularisation. EuroIntervention, 5(7),

763-767. Bito, V, Waard, M.C. de, Biesmans, L, Lenaerts, I, Ozdemir, S, Deel, E. van, Abdel-Mottaleb, Y, Driesen, R, Holemans, P,

Duncker, D.J.G.M. & Sipido, K.R. (2010). Early exercise training after myocardial infarction prevents contractile but not electrical remodelling or hypertrophy. Cardiovascular Research, 86(1), 72-81.

Blonk, M.I., Velde, N. van der, Bemt, P.M.L.A. van den, Schaik, R.H.N. van & Cammen, T.J.M. van der (2010). CYP2D6*4,

CYP3A5*3 and ABCB1 3435T polymorphisms and drug-related falls in elderly people. Pharmacy World & Science, 32(1), 26-29. Boer, R. de, Schaap, M.M., Lijn, F. van der, Vrooman, H.A., Groot, M. de, Vernooij, M.W., Ikram, M.A., Velsen, E.F.S. van, Lugt,

A. van der, Breteler, M.M.B. & Niessen, W.J. (2010). Statistical analysis of structural brain connectivity. Medical Image Computing and Computer-Assisted Intervention, 13(Pt 2), 101-108.

Boer, R.A. de, Martens, FM, Kuipers, I, Boomsma, F. & Visseren, F.L.J. (2010). The effects of the PPAR-gamma agonist

pioglitazone on plasma concentrations of circulating vasoactive factors in type II diabetes mellitus. Journal of Human Hypertension, 24, 74-76.

Boer, S.P.M. de, Westerhout, C.M., Simes, R.J., Granger, C.B., Zijlstra, F. & Boersma, E. (2010). Mortality and Morbidity

Reduction by Primary Percutaneous Coronary Intervention Is Independent of the Patient's Age. JACC-Cardiovascular interventions, 3(3), 324-331.

Bogaard, B van den, Draijer, R, Westerhof, B.E., Meiracker, A.H. van den, Montfrans, GA van & Born, BJH van den (2010).

Effects on Peripheral and Central Blood Pressure of Cocoa With Natural or High-Dose Theobromine A Randomized, Double-Blind Crossover Trial. Hypertension, 56(5), 839-U242.

Bogers, A.J.J.C., Head, S.J., Jong, P.L. de, Witsenburg, M. & Kappetein, A.P. (2010). Long term follow up after surgery in

congenitally corrected transposition of the great arteries with a right ventricle in the systemic circulation. Journal of cardiothoracic surgery, 5.

Bogers, A.J.J.C. (2010). Gestageerde chirurgische behandeling. Cordiaal, 4, 116-119. Bommel, J. van, Jonge, J. de, Buise, M.P., Specht, P.A.C., Genderen, M van & Gommers, D. (2010). The effects of intravenous

nitroglycerine and norepinephrine on gastric microvascular perfusion in an experimental model of gastric tube reconstruction. Surgery, 148(1), 71-77.

Bonati, LH, Jongen, LM, Haller, S, Flach, H.Z., Dobson, J., Nederkoorn, P.J., Macdonald, S, Gaines, P.A., Waaijer, A, Stierli, P,

Jager, HR, Lyrer, PA, Kappelle, L.J., Wetzel, SG, Lugt, A. van der, Mali, WP, Brown, M.M., Worp, H.B. van der & Engelter, ST (2010). New ischaemic brain lesions on MRI after stenting or endarterectomy for symptomatic carotid stenosis: a substudy of the International Carotid Stenting Study (ICSS). Lancet Neurology, 9(4), 353-362.

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Bongers, T.N., Emonts, M., Maat, M.P.M. de, Groot, R. de, Lisman, T., Hazelzet, J.A. & Leebeek, F.W.G. (2010). Reduced ADAMTS13 in children with severe meningococcal sepsis is associated with severity and outcome. Blood Coagulation & Fibrinolysis, 103, 1181-1187.

Bonta, PI, Pols, TWH, Tiel, CM van, Vos, M, Arkenbout, EK, Rohlena, J, Koch, K.T., Maat, M.P.M. de, Tanck, M.W.T., Winter,

RJ de, Pannekoek, H, Biessen, E.A.L., Bot, I & Vries, C.J.M. de (2010). Nuclear Receptor Nurr1 Is Expressed In and Is Associated With Human Restenosis and Inhibits Vascular Lesion Formation In Mice Involving Inhibition of Smooth Muscle Cell Proliferation and Inflammation. Circulation, 121(18), 2023-U135.

Boogers, MJ, Schuijf, JD, Kitslaar, PH, Werkhoven, JM van, Graaf, FR de, Boersma, E., Velzen, JE van, Dijkstra, J., Adame, IM,

Kroft, LJ, Roos, A. de, Schreur, JHM, Heijenbrok, M.W., Jukema, J.W., Reiber, J.H.C. & Bax, J.J. (2010). Automated Quantification of Stenosis Severity on 64-Slice CT A Comparison With Quantitative Coronary Angiography. JACC-cardiovascular imaging, 3(7), 699-709.

Boogers, MJ, Borleffs, CJW, Henneman, MM, Bommel, RJ van, Ramshorst, J van, Boersma, E., Dibbets-Schneider, P, Stokkel,

MP, Wall, E.E. van der, Schalij, M.J. & Bax, J.J. (2010). Cardiac Sympathetic Denervation Assessed With 123-Iodine Metaiodobenzylguanidine Imaging Predicts Ventricular Arrhythmias in Implantable Cardioverter-Defibrillator Patients. Journal of the American College of Cardiology, 55(24), 2769-2777.

Boomkens, H.R., Cammen, T.J.M. van der & Mattace Raso, F.U.S. (2010). Primary arachnoid cyst mimicking depressive

symptoms in an elderly woman. International Psychogeriatrics, 22(5), 832-833. Bosch, JA Ten, Rouwet, E.V., Peters, CTH, Jansen, L., Verhagen, H.J.M., Prins, MH & Teijink, JAW (2010). Contrast-enhanced

Ultrasound versus Computed Tomographic Angiography for Surveillance of Endovascular Abdominal Aortic Aneurysm Repair. Journal of Vascular and Interventional Radiology, 21(5), 638-643.

Bouman, HJ, Werkum, JW van, Rudez, G., Leebeek, F.W.G., Kruit, A., Hackeng, CM, Berg, JM van den, Maat, M.P.M. de &

Ruven, HJT (2010). The influence of variation in the P2Y12 receptor gene on in vitro platelet inhibition with the direct P2Y12 antagonist cangrelor. Thrombosis and Haemostasis, 103(2), 379-386.

Brown, JW, Elkins, R.C., Clarke, DR, Tweddell, JS, Huddleston, CB, Doty, JR, Fehrenbacher, JW & Takkenberg, J.J.M. (2010).

Performance of the CryoValve* SG human decellularized pulmonary valve in 342 patients relative to the conventional CryoValve at a mean follow-up of four years. Journal of Thoracic and Cardiovascular Surgery, 139(2), 339-348.

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