Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T....
Transcript of Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T....
![Page 1: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/1.jpg)
Embryology of the Neck & Neck Masses
Steven T. Wright, M.D.
Faculty Advisor: Shawn Newlands, M.D., Ph.D, M.B.A
The University of Texas Medical Branch
Department of Otolaryngology
Grand Rounds Presentation
June 8, 2005
![Page 2: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/2.jpg)
Neck Masses
A mass in the neck is a common clinical finding.
Benign Neoplasm
Malignant Neoplasm
Infectious
Congenital
![Page 3: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/3.jpg)
Neck Masses
An appreciation for the embryological development of the cervical structures must be made to competently understand and treat the disorders of the neck.
![Page 4: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/4.jpg)
End of first month
![Page 5: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/5.jpg)
4 weeks
![Page 6: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/6.jpg)
6 weeks
![Page 7: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/7.jpg)
8 weeks
![Page 8: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/8.jpg)
Embryology and Anatomy
Branchial System- 6 pairs of pharyngeal arches separated by endodermally lined pouches and ectodermally lined clefts.
Each arch consists of a nerve, artery, and cartilaginous structures.
The remaining neck musculature gains contributions from cervical somites.
![Page 9: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/9.jpg)
Branchial system
First Branchial arch
Maxillary and mandibular (Meckel’s) process regress to leave the malleus and incus.
Ossification around Meckel’s cartilage gives rise to the mandible, sphenomandibular ligament, and anterior malleolar ligaments.
Muscles- temporalis, masseter, pterygoids, mylohyoid, ant belly of digastric, tensor tympani, tensor veli palatini
![Page 10: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/10.jpg)
Branchial system
First Branchial Arch
Pouch
Eust tube, mid ear
Temporal bone
Cleft
EAC/TM
![Page 11: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/11.jpg)
Branchial system
Second Branchial Arch
Reichert’s cartilage contributes to the superstructure of the stapes, the upper body and lesser cornu of the hyoid, the styloid process and stylohyoid ligament.
Muscles- platysma, muscles of facial expression, posterior belly of digastric, stylohyoid, and stapedius
Nerve- 7th cranial nerve
Artery- stapedial artery
![Page 12: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/12.jpg)
Branchial system
Third Branchial Arch
Lower body of the hyoid and greater cornu.
Muscles- stylopharyngeus, superior and middle pharyngeal constrictors.
Nerve- 9th cranial nerve
Artery- common carotid and proximal portions of the internal and external carotid.
![Page 13: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/13.jpg)
Branchial system
Third Branchial Pouch
Inferior parathyroids
Thymus gland and thymic duct
![Page 14: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/14.jpg)
Branchial system
Fourth and Sixth Branchial arches fuse to form the laryngeal cartilages.
Fourth Arch
Muscles- cricothyroid, inferior pharyngeal constrictors
Nerve- Superior Laryngeal Nerve
Artery- Right Subclavian, Aortic arch
Fourth Pouch- superior parathyoid glands and parafollicular thyroid cells
![Page 15: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/15.jpg)
Branchial system
Sixth Branchial Arch
Muscles- remaining/intrinsic laryngeal musculature
Nerve- Recurrent Laryngeal Nerve
Artery- Pulmonary Artery and ductus arteriosus
![Page 16: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/16.jpg)
Branchial system
Epipericardial ridge- mesodermal elements of the sternocleidomastoid, trapezius, and lingual and infrahyoid musculature.
Nerve- hypoglossal and spinal accessory nerve
Cervical Sinus of His
![Page 17: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/17.jpg)
Thyroid Gland
Endoderm of the floor of mouth between the 1st and 2nd archs.
Descends as a bilobed diverticulum from the foramen cecum around the 4th week to rest by the 7-8th week.
![Page 18: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/18.jpg)
Oral Cavity
![Page 19: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/19.jpg)
Neck Masses
Midline Neck Masses Thyroid nodules Cervical Lymphadenopathy Thyroglossal Duct cyst Thymus gland anomalies Plunging ranula
Lateral Neck Masses Branchial cleft anomalies Laryngoceles Dermoid and Teratoid Cysts
![Page 20: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/20.jpg)
Midline Neck Masses
Thyroid nodules
Thyroglossal duct cyst
Cervical Thymic Cyst
Plunging ranula
![Page 21: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/21.jpg)
Thyroid Nodules
4% of population
1/20 will harbor Cancer
H&P combined with FNA is crucial for diagnosis
FNA Malignant
Suspicious
Benign
Indeterminate
![Page 22: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/22.jpg)
Fine-Needle Aspiration Biopsy Problems:
Sampling error
Small (<1 cm)
Large (>4 cm)
Hashimoto’s versus lymphoma
Follicular neoplasms
Fluid-only cysts
Somewhat dependent on skill of cytopathologist
![Page 23: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/23.jpg)
Flowchart
![Page 24: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/24.jpg)
Thyroglossal Duct Cyst
Most common congenital midline mass
Asymptomatic mass at or below the hyoid bone that elevates with tongue protrusion.
Ectopic thyroid tissue vs. thyroglossal duct cyst?
![Page 25: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/25.jpg)
Thyroglossal Duct Cyst
![Page 26: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/26.jpg)
Thyroglossal Duct Cyst
1-2% have Ectopic Thyroid glands so imaging is indicated to document presence of a normal or ectopic thyroid gland
Simple Excision leads to high recurrence rate
Sistrunk Procedure
Patients at high risk for recurrence- Modified Sistrunk Procedure
![Page 27: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/27.jpg)
TGDC Carcinoma
Uncommon, 1%
94% Thyroid- Papillary
6% Squamous Cell
TGDC Carcinoma or a Metastatic Cystic Thyroid Carcinoma in a Midline Lymph node?
![Page 28: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/28.jpg)
TGDC Carcinoma
Patel et al. “incidentally discovered, well-differentiated thyroid
CA in a low risk patient (<45yrs, <4cm, no local/regional invasion) can be adequately managed by Sistrunk.
In presence of a clinically/radiographically normal thyroid.
Other Convincing evidence: Lack of Lymph tissue Presence of Columnar or Squamous epithelium
Total thyroidectomy with or without neck dissection.
![Page 29: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/29.jpg)
Ectopic Thyroid
90% are lingual
1/3rd are hypothyroid- elevated TSH- goiter
Symptoms are of base of tongue obstruction, dysphagia
Surgical Excision
![Page 30: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/30.jpg)
Lateral Nonmalignant Thyroid Tissue
True Embyrologic rest of normal thyroid tissue as a result a migration error or is it a metastatic well differentiated thyroid carcinoma?
ANY suspicious findings should favor a metastatic deposit rather than LNTT.
Strict criteria must be followed for LNTT: must be small, with only a few thyroid follicles no atypical nuclear features of papillary carcinoma should be present only in the capsular region of
the node
![Page 31: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/31.jpg)
Cervical Thymic Cysts
Failure of involution of the cervical thymopharyngeal ducts.
Firm, mobile masses found in the lower aspects of the neck.
CXR, CT scan
Surgical Excision- Inferior limit of dissection is the brachiocephalic v.
![Page 32: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/32.jpg)
Plunging Ranula
Simple ranula- unilateral oral cavity cystic lesion.
Plunging ranula- pierce the mylohyoid to present as a paramedian or lateral neck mass.
Cyst aspirate- high protein, amylase levels
CT scan/MRI
Treatment is intraoral excision to include the sublingual gland of origin.
![Page 33: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/33.jpg)
Plunging Ranula
![Page 34: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/34.jpg)
Lateral Neck Masses
Branchial cleft anomalies
Laryngoceles
Dermoid and Teratoid Cysts
Sternocleidomastoid Pseudotumor of Infancy
![Page 35: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/35.jpg)
First Branchial Cleft Cysts
Type I
Ectodermal Duplication anomaly of the EAC with squamous epithelium only.
Parallel to the EAC
Pretragal, post auricular
Connection with TM or Malleus>Incus
Surgical Excision
![Page 36: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/36.jpg)
First Branchial Cleft Cysts
Type II
Squamous epithelium and other ectodermal components
Anterior neck, superior to hyoid bone.
Courses over the mandible and through the parotid in variable position to the Facial Nerve.
Terminates near the EAC bony-cartilaginous junction.
Surgical excision- superficial parotidectomy
![Page 37: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/37.jpg)
First Branchial Cleft Cysts
![Page 38: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/38.jpg)
Second Branchial Cleft Cysts
Most Common (90%) branchial anomaly
Painless, fluctuant mass in anterior triangle
Inferior-middle 2/3 junction of SCM, deep to platysma, lateral to IX, X, XII, between the internal and external carotid and terminate in the tonsillar fossa
Surgical treatment may include tonsillectomy
![Page 39: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/39.jpg)
Second Branchial Cleft Cysts
![Page 40: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/40.jpg)
Third Branchial Cleft Cysts
Rare (<2%)
Similar external presentation to 2nd BCC
Internal opening is at the pyriform sinus, then courses cephalad to the superior laryngeal nerve through the thyrohyoid membrane, medial to IX, lateral to X, XII, posterior to internal carotid
Surgical approach must visualize recurrent layngeal nerves- Thyoidectomy incision
![Page 41: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/41.jpg)
Third Branchial Cleft Cysts
![Page 42: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/42.jpg)
Fourth Branchial Cleft Cysts
Courses from pyriform sinus apex caudal to superior laryngeal nerve, to emerge near the cricothryoid joint, and descend superficial to the recurrent laryngeal nerve.
![Page 43: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/43.jpg)
Laryngoceles
Congenitally from an enlarged laryngeal saccule.
Classified as internal, external, or both
Internal
Confined to larynx, usually involves the false cord and aryepiglottic fold.
Hoarseness and respiratory distress vs. neck mass.
![Page 44: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/44.jpg)
Laryngoceles
External and Combined Laryngoceles
Soft, compressible, lateral neck mass that distends with increases in intralaryngeal pressures.
Through the thyrohyoid membrane at the entrance of the Superior Laryngeal Nerve.
CT scan
Asymptomatic vs Symptomatic laryngoceles.
![Page 45: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/45.jpg)
Laryngoceles
![Page 46: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/46.jpg)
Laryngoceles
1-3% of Laryngoceles will harbor an underlying laryngeal carcinoma
ALL adult patients should undergo direct laryngoscopy at the time of surgical intervention.
![Page 47: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/47.jpg)
Dermoid and Teratoid Cysts
Developmental anomalies composed of different germ cell layers.
Isolation of pluripotent stem cells or closure of germ cell layers within points of failed embryonic fusion lines.
Classified according to composition.
![Page 48: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/48.jpg)
Dermoid Cysts
Mesoderm and Ectoderm
Midline, paramedian, painless masses that usually do not elevate with tongue protrusion.
Commonly misdiagnosed as Thyroglossal Duct Cysts.
Treatment is simple surgical excision
![Page 49: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/49.jpg)
Teratoid Cysts and Teratomas
All three germ cell layers- Endoderm, mesoderm and ectoderm.
Larger midline masses, present earlier in life.
20% associated maternal polyhydramnios
Unlike adult teratomas, they rarely demonstrate malignant degeneration.
Surgical excision.
![Page 50: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/50.jpg)
Sternomastoid Tumor of Infancy (Psuedotumor)
Firm mass of the SCM, chin turned away and head tilted toward the mass.
Hematoma with subsequent fibrotic replacement.
Ultrasound
Physical therapy is very successful.
Myoplasty of the SCM only if refractory to PT.
![Page 51: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/51.jpg)
Sternomastoid Tumor of Infancy
![Page 52: Embryology of the Neck & Neck Masses · PDF fileEmbryology of the Neck & Neck Masses Steven T. Wright, ... Nerve- 7th cranial nerve ... Nerve- hypoglossal and spinal accessory](https://reader031.fdocuments.net/reader031/viewer/2022022003/5aa3d8447f8b9a46238edf57/html5/thumbnails/52.jpg)
Conclusions
Neck masses are very common
Approach with History and Physical exam will commonly lead to the correct diagnosis
An understanding of cervical embryology is crucial in treatment of these masses