Elimination of Mother-to-Child Transmission of HIV...
Transcript of Elimination of Mother-to-Child Transmission of HIV...
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Elimination of Mother-to-Child Transmission of HIV , Examples of Success from Thailand
20 July 2016Durban, South Africa
Dr. Sarawut Boonsuk
Chief of Maternal and Child Health,
Department of Health, Thailand
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Outlines
• Performance of the PMTCT program in Thailand
• Overview of PMTCT of HIV and syphilis program
o Roles and responsibilities of MOPH and others at national and sub national level
o How the program is resourced and monitored
• Main challenges and ways forward
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Health Service Delivery System in Thailand
Health centers9,892 #
Municipality Medical Centers
486 #
District hospitals780 # (714*)
Provincial/General hospitals 83 # (83*)
Private clinics6,421 #
Other Public Hospitals116 # (34*)
Private Hospitals
342 #
(164*)
Regional hospitals 33# (33*)
Other MoPHhospitals 57# (13*)
MOPH Facilities
Sub-district
District
Province
Source: 1. Thailand Health Profile: MOPH Calendar 20162. #Number of health service facilities3. * Number of facilities providing delivery services: source Bureau of Policy and
Strategy, MoPH: http://www.hrm.moph.go.th/healthmap/gmap.php#result
Other Gov’t Facilities
Private Facilities
(137 # (55*) hos)(953# (843*) hos)
Pharmacy
14,576 #
University Hospitals 21 #
(21*)
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Thai National PMTCT Policy Evolution
2000 2004 2005 2007 2010 2014
PMTCT infant AZT x 4 wks
AZT x 4 wksorAZT/3TC 6 wks
+NVP 2-4 wks
AZT x 4 wks orAZT/3TC/NVP 6 wks
PMTCTPregnant women Short course
AZT(34 wks)
AZT 28 wks+ NVP 1 dose
HAART for all pregnant women (14 wks) and continue for eligible women
HAART for all ASAP and continue HAART for all who are willing to take ART
AZT 28 wks+ NVP 1 dose and HAART for eligible women
VCT/PITC
Couples HIV testing and counselingVCT
Infant formula (12 mo) - Infant formula (18 mo)Infant feeding
DNA PCR (2 times)
- HIV antibody at 12-18 months
Early infant diagnosis DNA PCR based on risk
of MTCT
1993-2000 VCT and infant formula x 12 mo
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Goal for Elimination Mother-to-Child HIV Transmission, in Thailand by 2016
1. 50% reduction in number of new pediatric HIV infection
2. 50% reduction of AIDS mortality rate among HIV+
mothers and babies
50% reduction of AIDS mortality
in children
-Promote early infant diagnosis-Early access to Rx and care
-Improve quality of pediatric HIV treatment, promote ARV adherence and reduce complication
Reduction of new HIV infection among women
15-45 years for 2/3 of estimated number
Reduction of unmet family planning
need to zero
Reduce MTCT rate to < 2%
95% of HIV+mothersand family refer to treatment and care
Prong 1 target
Prong 2target
Prong 3target
Prong4target
sarawut boonsuk DOH,MOPH 2012
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HIV MTCT Rates (GARP report 2008-2015)
4.6
3.93.4
3.12.7 2.3 2.1
2.3 2 1.9
0
1
2
3
4
5
2008 2009 2010 2011 2012 2013 2014 2015
National adjusted MTCT rate
SPECTRUM v. 5.4
(2013-2015 used SPECTRUM data)
0.0
0.7 0.71.0 1.0
1.4 1.51.8
1.6
2.3
1.81.7
1.51.7
1.5 1.4 1.41.2 1.1
0.9 0.9 0.80.7 0.6 0.6 0.6
0
1
2
3
4
5
6Sentinel
PHIMS-ANC
PHIMS-No ANC
Sources: serosentinel surveillance, BoE PHIMS, Department of Health
HIV Prevalence in Pregnant Women by ANC Status
15
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The Thai government provides most of the budget for PMTCT of HIV (>90%)National spending for PMTCT in 2008 was 4.4 million USD, declining to 2.3 million USD in 2013
NASA 2014
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Conclusions: Success and Sustainability of EMTCT of HIV and Syphilis in Thailand
• National ownership and leadership
• Sustained political commitment
• A favorable legal and policy environment
• A well-developed national health system
• The consistent strengthening of its building blocks
• Enhancement of community systems
• The strengthening of community interface with health systems
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Acknowledgements• Department of Health
– Dr. Danai Teewanda
– Dr. Sarawut Boonsuk
– Ms. Chaweewan Tondputsa
• Department of Medical Science
– Dr. Busarawan Sriwantana
– Ms. Hansa Thaisri
• Department of Diseases Control
– Dr. Petchsri Sirinirund
– Dr. Sumet Ongwandee
– Dr. Nisit Kongkergkiat
• Thai red cross AIDS research center
– Dr. Praphan Phanuphak
• All hospitals submitted PMTCT reports and implemented PMTCT services
• Members of the
– National validation committee
– EMTCT working groups
• Global AIDS Program Thailand/Asia Regional office• Dr. Rangsima Lolekha• Ms. Benjamas Baipluthong• Dr. Chonticha Kittinunvorakoon• Dr. Michael Martin• Dr. Thierry Roels
• UNICEF Thailand and UNICEF EPRO• Dr. Beena Kuttparambil• Ms. Wing-Sie Cheng
• NGOs and human right working group• Dr. Suchada Taweesith• Ms. Sulaiporn Chonwilai
• UNAIDS Thailand• Ms. Tatiana Shommulan• Dr. Patchara Benjarattanaporn• Mr. Sompong Chareonsuk
• WHO Thailand and SEARO• Dr. Mukta Sharma• Dr. Razia Narayan Pendse
• NHSO, SSS, CSMB, and BPS• Dr. Suchada Chaiwut