Eight Applications of Liquid Biopsy (Part Two)
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Eight Applications of Liquid Biopsy (PartTwo)
Posted By biomart on September 17, 2015
The last post has given an introduction to liquid biopsy and its first four applications. This post is to analyze this rest four:
Cancer TreatmentCancer Treatment
Last year, some companies began to establish genetic map of cancer through mutated DNA fragments found in the blood. This“diagnosis and treatment” test can be used to determine which medication is suitable for the patients because cancer is causedby a specific mutation and they have a good response to certain drugs.
Moreover, since the amount of tumor DNA in the blood is in proportion to the DNA size and stage, this detection can also beapplied to determine the effect of surgery or drug treatment. For some disease like lung cancer that tissue biopsy is hard to tacklewith, liquid biopsy is particularly useful.
Cancer predictionCancer prediction
In the early future, a major application of liquid biopsy is to detect cancer before any symptoms appear. Studies have shown thatblood tests can detect tumor before seeing it. This screening test is still in the development stage and it may still need years ofstudy.
Organ TransplantationOrgan Transplantation
Kidney, heart or liver transplants may also be considered as genome transplantation. After the transplant, the cells containing the
NDA of other people appeared in the recipient’s body. Doctors believe that tracking those DNA by liquid biopsy can determinewhether they are excluded by the organs. Researchers at Stanford University collected the blood of 44 adults and 21 childrenheart transplant patients, and they found that they can track the signs of organ rejection. For those patients receiving bonemarrow transplants, liquid biopsy is also proved to be useful.
Type I diabetesType I diabetes
In type I diabetes, the body killed β cells that producing insulin because of immune response. This year, a group of US scientistshave collected the blood of 50 people who are suffering from disease risk, trying to find excess DNA of β cells.
Posted in Hotspot Tagged Cancer prediction, Cancer Treatment, creativebiomart, Type I diabetes
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