1

Efficiency and Transparencyin Genetic Diagnostics

Mark Harris, PhD, MBAFounder/CEO, NextGxDx

January 27, 2016

Precision Medicine in the Clinical Workflow

PAYERS

LABSCLINICIANS

HOSPITALS

Search the genetic testing marketplace.

60,482genetic testing products

as of January 11, 2016

WE PULL DATA FROM

300 LABS

AND ACTIVELY PROCESS

3 MILLIONDATA POINTS PER MONTH

Market Growth (New Products): July 2014 - January 2016

4

Panels account for 10% of our total catalog

but they account for

24% of growthin the last 18 months.

search compare order

6

Variation in Clinical Workflow

DxEMR

LIMS

ReferenceLaboratory

scan

SpecimenProcessing

Sendout Lab

search compare order results

8

Adapting to Workflow

confidential

A selection of examples:

ü Add tube type to sample collection infoü Add indication and ethnicity fieldsü Add concurrent/sequential to ordering

processü Ability to display multiple prices in

marketplaceü “No charge” billing optionü Collect genetic counselor and sendout lab

user infoü Bypass compare step if use product searchü Ability to customize sorting of lab/test resultsü Ability to re-configure approval workflow

policies

DxEMR

LIMS

ReferenceLaboratory

scan

SpecimenProcessing

Sendout Lab

search compare order results payment

11

EnablingEfficiency and Transparency

in Genetic Diagnostics

Key LessonsHigh growth rate requires technology solution

Common terminology is a necessary precursor to transparency, efficiency, and effective integration into the clinical workflow.

Ordering behavior varies significantly and is highly manual

Genetic testing results typically unstructured

Coding, billing and reimbursement are the next horizon within genetics clinical workflow