Efficacy of tart cherry juice in reducing muscle
Transcript of Efficacy of tart cherry juice in reducing muscle
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Efficacy of tart cherry juice in reducing
muscle pain during running :a randomized controlled trial
MARNIAR
C209118041
Kuehl et al.
Journal of the International Society of Sports Nutrition 2010, 7:17
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INTRODUCTION
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Long distance
runningacute muscle damage
acute inflammation
decreased forceproduction
can last up to
1 week
post-exercise
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One proposed mechanism :
extensive myofibril disruption triggers a
local inflammatory response
MUSCLE DAMAGE
NSAIDsadverseeffects >>
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Tart cherries :
a good source of phenolic
compounds withhighlevels of
antioxidant and antiinflammatory
activity
cherry consumption before and
during strenuous exercise mayhave a protectiveeffect to reduce
muscle damage andpain
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Some studies :
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Consumption of approximately 45 cherries per
day has been shown to reduce circulating
concentrations of inflammatory markers in
health
y men and wom
en (Connolly DA et.al., 2006 ;Jacob RA et.al., 2003)
it is possible that the anti-inflammatory and/or
the antioxidant effects of cherry juice may
mediate this secondary response and avoid theproliferation of myofibrillar disruption
(Connolly DA et.al., 2003)
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METHODS
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EXCLUSION
CRITERIA :
recent use of other
pain management
methods
ARANDOMIZED, PLACEBO-CONTROLLED,DOUBLE- BLINDTRIAL
ICLUSIONCRITERIA :
an ability and
willingness to abstain
from anti-inflammatory
or pain-relieving drugs
willingness to refrain
from seeking any othertreatment for symptoms
of muscle damageuntil
the completion of the
study
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RESULT
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runners in both groups reported more pain
upon completion of the race
participants who drank the tart cherry juice
twice daily for one week prior to and the
day of the race reported a significantlysmaller increase in pain after the race
In this study
tart cherry juice provideda protective benefit against
the acute muscle pain
caused by distance running
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pain associated with acute muscle injury is most
likely due to oxidative tissue damage whichleads
to an inflammatory response, causing furtherproduction of free radicals and augmenting
secondary muscle soreness
nutritional antioxidants have been proposed as a
means of mitigating muscle soreness and strength
loss caused by damaging exercise
tart cherries contain flavinoids and
anthocyanins, withhigh antioxidant
and anti-inflammatory properties
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Limitations of this study
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the subjective of assessment of pain by
participants
the possibility of cross contamination of the
intervention and placebo drinks, as participantsmay have potentially switched drinks to compare
flavor and effects
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CONCLUSIONS
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tart cherries havehighlevels of antioxidant and
anti-inflammatory compounds, and are promoted in
lay publications as beneficial for those witharthritis, muscle pain, and fibromyalgia
the present study suggests that the administration
of tart cherry juice foreight days reducedsymptoms ofexercise-induced muscle pain among
runners participating in a vigorous endurance
event
further research is needed to examine serum
biomarkers and the potentialexplanation for the
reduction in pain and inflammation associated with
tart che
rry consu
mption
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terima kasih
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VAS pain scale
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VAS pain scale