DYNASAN 118 - IOI Oleo GmbH€¦ · DYNASAN® 118 is a multifunctional excipient, used primarily as...
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IOI Oleo GmbH PHARMA DYNASAN ® 118 GLYCERYL TRISTEARATE THE LIPID FOR SOLID DOSAGE FORMS
Transcript of DYNASAN 118 - IOI Oleo GmbH€¦ · DYNASAN® 118 is a multifunctional excipient, used primarily as...
IOI Oleo GmbH
PHARMA
DYNASAN® 118GLYCERYL TRISTEARATE
THE LIPID FOR SOLID DOSAGE FORMS
DYNASAN® 118 is a multifunctional excipient, used primarily as a tablet aid with lubricating and retarding functions.
Versatile excipient for solid dosage forms
DYNASAN® 118 Glyceryl Tristearate
CharacteristicsDYNASAN® 118 is a monoacid triglyceride based on C18 fatty acid with a high melting point (approx. 73°C). It is available as a microfine powder and suitable for oral solid dosage matrices.
Properties and Applications modified / retard oral dosage forms with enhanced concentra-
tions (2–5%) through an increase of the hydrophobic character
no influence on drug release up to concentration of 1%
effective lubricant for tablet production in low concentrations (~ 0.5%)
enhances the tablet fracture stability due to an increased lubrici-ty factor as a consequence of particle morphology and particle surface
used for taste masking, applying hot melt coating technique
suitable for hot melt extrusion and hot melt granulation
utilisable for generating solid lipid nanoparticles (SLN)
DYNASAN® 118 production is fully EU GMP-certified.
IOI Oleo GmbHHamburg, Germany | +49 40 28 00 31-0 | [email protected] | www.ioioleo.de
